EXPERIMENT ID PUBMED ID SPECIES EXPERIMENT DESCRIPTION SAMPLE SAMPLE SOURCE SAMPLE NAME IDENTIFICATIONS METHODS YEAR ISOLATION METHOD VESICLE TYPE 1 6307529 Ovis aries Fate of the transferrin receptor during maturation of sheep reticulocytes in vitro: selective externalization of the receptor. Reticulocytes ts Reticulocytes Protein Antibody based methods 1983 - Exosomes 2 3597417 Ovis aries Vesicle formation during reticulocyte maturation. Association of plasma membrane activities with released vesicles (exosomes). Reticulocytes ts Reticulocytes Protein|Lipids Enzyme assay|Antibody based methods 1987 Differential centrifugation Exosomes 3 10545503 Mus musculus Molecular characterization of dendritic cell-derived exosomes. Selective accumulation of the heat shock protein hsc73. Dendritic cells cl D1 Protein Mass spectrometry [MALDI TOF]|Western blotting 1999 Differential centrifugation|Sucrose density gradient Exosomes 4 11487543 Homo sapiens Intestinal epithelial cells secrete exosome-like vesicles. Epithelial cells cl HT29-19A|T84-DRB1*0401/CIITA (intestinal epithelial cells) Protein Mass spectrometry [MALDI TOF]|Western blotting 2001 Differential centrifugation|Sucrose density gradient Exosomes 5 11145662 Mus musculus Mast cell-dependent B and T lymphocyte activation is mediated by the secretion of immunologically active exosomes. Mast cells cl P815|MC9|Bone marrow-derived mast cells Protein Mass spectrometry [MALDI TOF]|ELISA 2001 Differential centrifugation Exosomes 6 11306949 Mus musculus Nonspecific B and T cell-stimulatory activity mediated by mast cells is associated with exosomes. Mast cells ts Bone marrow-derived mast cells Protein Western blotting 2001 - Exosomes 7 12626558 Mus musculus Mast cell-derived exosomes induce phenotypic and functional maturation of dendritic cells and elicit specific immune responses in vivo. Mast cells ts Bone marrow-derived mast cells Protein Western blotting 2003 Differential centrifugation Exosomes 8 12626558 Mus musculus Mast cell-derived exosomes induce phenotypic and functional maturation of dendritic cells and elicit specific immune responses in vivo. B cells ts B cells Protein Western blotting 2003 Differential centrifugation Exosomes 9 12626558 Mus musculus Mast cell-derived exosomes induce phenotypic and functional maturation of dendritic cells and elicit specific immune responses in vivo. Macrophage ts Macrophages Protein Western blotting 2003 Differential centrifugation Exosomes 10 11390481 Mus musculus Proteomic analysis of dendritic cell-derived exosomes: a secreted subcellular compartment distinct from apoptotic vesicles. Dendritic cells cl D1 Protein Mass spectrometry [MALDI TOF]|Mass spectrometry [QTOF]|Western blotting 2001 Differential centrifugation|Sucrose density gradient Exosomes 11 12519789 Homo sapiens Proteomic and biochemical analyses of human B cell-derived exosomes. Potential implications for their function and multivesicular body formation. B cells cl RN (HLA-DR15+) Protein|Lipids Mass spectrometry [MALDI TOF]|Mass spectrometry [QTOF]|Western blotting|Thin layer chromatography|High performance liquid chromatography 2003 Differential centrifugation|Sucrose density gradient Exosomes 12 15478216 Homo sapiens Proteomic analysis of melanoma-derived exosomes by two-dimensional polyacrylamide gel electrophoresis and mass spectrometry. Melanoma cells cl MeWo|SK-MEL-28 Protein Mass spectrometry [4700 Proteomics Analyzer]|Western blotting 2004 Filtration|Ultracentrifugation|Sucrose density gradient Exosomes 13 15326289 Homo sapiens Identification and proteomic profiling of exosomes in human urine. Urine ts Urine - Normal Protein Mass spectrometry [LCQ DECA XP]|Western blotting 2004 Ultracentrifugation Exosomes 14 16081791 Mus musculus Proteomic analysis of microglia-derived exosomes: metabolic role of the aminopeptidase CD13 in neuropeptide catabolism. Microglia cl N9 Protein Mass spectrometry [LCQ DECA XP]|Western blotting 2005 Differential centrifugation|Sucrose density gradient Exosomes 15 17486113 Mus musculus|Homo sapiens Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Mast cells cl|ts MC9|Bone marrow-derived mast cells|HMC-1 Protein|mRNA|miRNA Mass spectrometry [MALDI TOF]|Western blotting|Microarray|MicroRNA array [miRCURY LNA Array] 2007 Filtration|Ultracentrifugation|Sucrose density gradient Exosomes 16 9685355 Homo sapiens Selective enrichment of tetraspan proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B-lymphocytes. B cells cl RN (HLA-DR15+) Protein Western blotting|Immunoelectron microscopy 1998 Differential centrifugation|Sucrose density gradient Exosomes 17 11907077 Homo sapiens TCR activation of human T cells induces the production of exosomes bearing the TCR/CD3/zeta complex. T cells cl Jurkat|T cell blasts|E+ cells|MART-1+ T cell Protein Western blotting|Immunoelectron microscopy 2002 Filtration|Ultracentrifugation Exosomes 18 11907077 Homo sapiens TCR activation of human T cells induces the production of exosomes bearing the TCR/CD3/zeta complex. T cells cl Jurkat|T cell blasts Protein FACS 2002 Filtration|Ultracentrifugation Exosomes 19 16302729 Homo sapiens Purification, characterization and biological significance of tumor-derived exosomes. Breast cancer cells cl BT-474|MDA-MB-231 Protein Western blotting|FACS 2005 Differential centrifugation|Sucrose density gradient|Filtration|Immunobeads(HER2) Exosomes 20 17956143 Homo sapiens Proteomic analysis of microvesicles derived from human colorectal cancer cells. Colorectal cancer cells cl HT29 Protein Mass spectrometry [LTQ]|Western blotting 2007 Differential centrifugation|Sucrose density gradient|Diafiltration Exosomes 21 19837982 Homo sapiens Proteomic and bioinformatic analysis of immunoaffinity-purified exosomes derived from the human colon tumor cell line LIM1215. Colorectal cancer cells cl LIM1215 Protein Mass spectrometry [Orbitrap]|Western blotting 2009 Filtration|Ultracentrifugation|Sucrose density gradient Exosomes 22 15940614 Homo sapiens Human colorectal cancer cells induce T-cell death through release of proapoptotic microvesicles: role in immune escape. Colorectal cancer cells cl SW403|1869col|CRC28462 Protein Western blotting|Immunoelectron microscopy|FACS 2005 Differential centrifugation Exosomes 23 11231627 Mus musculus Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming. Breast cancer cells cl TS/A (H-2d)|P815 mastocytoma cells (H-2d) Protein Western blotting|Immunoelectron microscopy 2001 Differential centrifugation|Sucrose density gradient Exosomes 24 11231627 Homo sapiens Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming. Melanoma cells cl Fon|Mel-888 Protein Western blotting 2001 Differential centrifugation|Sucrose density gradient Exosomes 25 15111327 Homo sapiens Proteomic analysis of exosomes secreted by human mesothelioma cells. Mesothelioma cells cl PMR-MM7|PMR-MM8 Protein Mass spectrometry [MALDI TOF]|Western blotting 2004 Differential centrifugation Exosomes 26 19109410 Mus musculus Proteomic and immunologic analyses of brain tumor exosomes. Brain cancer cells cl SMA560vIII Protein Mass spectrometry [MALDI TOF/TOF]|Western blotting 2008 Differential centrifugation|Sucrose density gradient Exosomes 27 19109410 Homo sapiens Proteomic and immunologic analyses of brain tumor exosomes. Medulloblastoma cells cl D283MED Protein Western blotting 2008 Differential centrifugation|Sucrose density gradient Exosomes 28 19109410 Homo sapiens Proteomic and immunologic analyses of brain tumor exosomes. Glioma cells cl X43,T|D456MG|H2159MG|D54MG|D247MG Protein Western blotting 2008 Differential centrifugation|Sucrose density gradient Exosomes 29 19109410 Homo sapiens Proteomic and immunologic analyses of brain tumor exosomes. Serum ts Serum - Brain tumor Protein Western blotting 2008 Differential centrifugation|Sucrose density gradient Exosomes 30 16446100 Rattus norvegicus Exosomes are released by cultured cortical neurones. Cortical neurons ts Neurones Protein Mass spectrometry [QTOF]|Western blotting 2006 Differential centrifugation|Sucrose density gradient Exosomes 31 10572093 Homo sapiens Activated platelets release two types of membrane vesicles: microvesicles by surface shedding and exosomes derived from exocytosis of multivesicular bodies and alpha-granules. Platelets ts Platelets Protein Western blotting|FACS|Immunoelectron microscopy 1999 Differential centrifugation|Sucrose density gradient Exosomes 32 18452139 Homo sapiens Primary human keratinocytes externalize stratifin protein via exosomes. Keratinocytes ts Keratinocytes Protein Western blotting 2008 Differential centrifugation|Sucrose density gradient|Diafiltration Exosomes 33 21136642 Mus musculus Oligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons? Oligodendrocytes ts Oligodendrocytes|Oli-neu Protein Mass spectrometry [QTOF]|Western blotting|Immunoelectron microscopy 2007 Differential centrifugation|Sucrose density gradient Exosomes 34 19190083 Homo sapiens Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense. Tracheobronchial cells ts Tracheobronchial epithelial cells Protein|mRNA Mass spectrometry [QTOF]|Western blotting|Immunoelectron microscopy|FACS 2009 Differential centrifugation|Filtration|Sucrose density gradient Exosomes 35 19367702 Rattus norvegicus Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes. Hepatocytes ts Hepatocytes Protein Mass spectrometry [QTOF]|Western blotting 2008 Differential centrifugation|Filtration|Sucrose density gradient Exosomes 36 19367702 Mus musculus Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes. Hepatocytes cl MLP-29 Protein Western blotting 2008 Differential centrifugation|Filtration Exosomes 37 10878338 Homo sapiens Direct immunosuppressive effects of EBV-encoded latent membrane protein 1. B cells cl JY|B95-8 Protein Western blotting 2000 Differential centrifugation Exosomes 38 15210972 Oryctolagus cuniculus Cells release prions in association with exosomes. Epithelial cells cl RK13 (Rov epithelial cells) Protein Western blotting|Immunoelectron microscopy 2004 Differential centrifugation|Sucrose density gradient Exosomes 39 15210972 Mus musculus Cells release prions in association with exosomes. Mov neuroglial cell cl Mov neuroglial cell Protein Mass spectrometry [QSTAR]|Western blotting|Immunoelectron microscopy 2004 Differential centrifugation|Sucrose density gradient Exosomes 40 15908444 Homo sapiens Exosomal-like vesicles are present in human blood plasma. Plasma ts Plasma - Normal Protein Western blotting|FACS|Immunoelectron microscopy 2005 Differential centrifugation|Filtration|Sucrose density gradient Exosomes 41 15908444 Homo sapiens Exosomal-like vesicles are present in human blood plasma. Mast cells cl HMC-1 Protein Western blotting|FACS|Immunoelectron microscopy 2005 Differential centrifugation|Filtration|Sucrose density gradient Exosomes 42 15908444 Homo sapiens Exosomal-like vesicles are present in human blood plasma. Bone marrow cells cl PBMC Protein Western blotting 2005 Differential centrifugation|Filtration|Sucrose density gradient Exosomes 43 17076679 Homo sapiens Specific isolation of placenta-derived exosomes from the circulation of pregnant women and their immunoregulatory consequences. Plasma ts Plasma - Pregnant and not-pregnant women Protein Western blotting 2006 Size exclusion chromatography|Ultracentrifugation|Immunobeads (CD3, CD19, CD56, CD83, PLAP) Exosomes 44 19028452 Homo sapiens Proteomic profiling of human plasma exosomes identifies PPARgamma as an exosome-associated protein. Plasma ts Plasma Protein Mass spectrometry [LTQ]|Western blotting|Immunoelectron microscopy 2009 Filtration|Size exclusion chromatography|Sucrose density gradient Exosomes 45 18589210 Homo sapiens MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer. Serum ts Serum - Papillary adenocarcinoma of ovary Protein|miRNA Western blotting|MicroRNA array 2008 Ultracentrifugation|Immunobeads (EpCAM) Exosomes 46 17641064 Homo sapiens Exosomes with immune modulatory features are present in human breast milk. Breast milk ts Breast milk - colostrum Protein Mass spectrometry [QSTAR]|Western blotting|Immunoelectron microscopy|FACS 2007 Differential centrifugation|Filtration|Sucrose density gradient Exosomes 47 17641064 Homo sapiens Exosomes with immune modulatory features are present in human breast milk. B cells cl B cells Protein FACS 2007 Differential centrifugation|Filtration|Sucrose density gradient Exosomes 48 17641064 Homo sapiens Exosomes with immune modulatory features are present in human breast milk. Breast milk ts Breast milk - mature milk Protein Mass spectrometry [QSTAR]|Western blotting|Immunoelectron microscopy|FACS 2007 Differential centrifugation|Filtration|Sucrose density gradient Exosomes 49 14582906 Homo sapiens Exosomes with major histocompatibility complex class II and co-stimulatory molecules are present in human BAL fluid. Bronchoalveolar lavage fluid ts Bronchoalveolar lavage fluid Protein FACS|Immunoelectron microscopy 2003 Differential centrifugation|Immunobeads (EpCAM) Exosomes 50 14582906 Homo sapiens Exosomes with major histocompatibility complex class II and co-stimulatory molecules are present in human BAL fluid. Dendritic cells ts Monocyte-derived dendritic cells Protein FACS|Immunoelectron microscopy 2003 Differential centrifugation|Immunobeads (EpCAM) Exosomes 51 14975938 Homo sapiens Proteomic analysis of exosomes isolated from human malignant pleural effusions. Malignant pleural effusions ts Pleural Fluid - Breast cancer Protein Mass spectrometry [MALDI TOF]|Western blotting 2004 Differential centrifugation|Sucrose density gradient Exosomes 52 14975938 Homo sapiens Proteomic analysis of exosomes isolated from human malignant pleural effusions. Malignant pleural effusions ts Pleural Fluid - Lung cancer Protein Mass spectrometry [MALDI TOF]|Western blotting 2004 Differential centrifugation|Sucrose density gradient Exosomes 53 14975938 Homo sapiens Proteomic analysis of exosomes isolated from human malignant pleural effusions. Malignant pleural effusions ts Pleural Fluid - Mesothelioma Protein Mass spectrometry [MALDI TOF]|Western blotting 2004 Differential centrifugation|Sucrose density gradient Exosomes 54 14975938 Homo sapiens Proteomic analysis of exosomes isolated from human malignant pleural effusions. Malignant pleural effusions ts Pleural Fluid - Ovarian adenocarcioma Protein Western blotting 2004 Differential centrifugation|Sucrose density gradient Exosomes 55 12147373 Homo sapiens Malignant effusions and immunogenic tumour-derived exosomes. Malignant pleural effusions ts Malignant pleural effusions Protein Western blotting 2002 Differential centrifugation|Sucrose density gradient Exosomes 56 12147373 Homo sapiens Malignant effusions and immunogenic tumour-derived exosomes. Ascites ts Malignant ascites Protein Western blotting 2002 Differential centrifugation|Sucrose density gradient Exosomes 57 17700640 Homo sapiens CD24 is a marker of exosomes secreted into urine and amniotic fluid. Urine ts Urine - Normal Protein Western blotting|FACS 2007 Differential centrifugation|Sucrose density gradient Exosomes 58 17700640 Homo sapiens CD24 is a marker of exosomes secreted into urine and amniotic fluid. Amniotic fluid ts Amniotic fluid Protein Western blotting 2007 Differential centrifugation|Sucrose density gradient Exosomes 59 17700640 Mus musculus CD24 is a marker of exosomes secreted into urine and amniotic fluid. Amniotic fluid ts Amniotic fluid Protein Western blotting 2007 Differential centrifugation|Sucrose density gradient Exosomes 60 17700640 Mus musculus CD24 is a marker of exosomes secreted into urine and amniotic fluid. Urine ts Urine - Normal Protein Western blotting 2007 Differential centrifugation|Sucrose density gradient Exosomes 61 17133577 Mus musculus Association of citrullinated proteins with synovial exosomes. Synovial fluid ts Synovial fluid - osteoarthritis and reactive arthritis Protein Immunoelectron microscopy|Mass spectrometry [MALDI TOF]|Western blotting 2006 Differential centrifugation|Sucrose density gradient Exosomes 62 17133577 Mus musculus Association of citrullinated proteins with synovial exosomes. Synovial fluid ts Synovial fluid - rheumatoid arthritis Protein Immunoelectron microscopy|Mass spectrometry [MALDI TOF]|Western blotting 2006 Differential centrifugation|Sucrose density gradient Exosomes 63 19056867 Homo sapiens Large-scale proteomics and phosphoproteomics of urinary exosomes. Urine ts Urine - Normal Protein Mass spectrometry [LTQ]|Western blotting 2009 Differential centrifugation Exosomes 64 18520029 Homo sapiens Exosome-like vesicles with dipeptidyl peptidase IV in human saliva. Saliva ts Saliva Protein Western blotting|Immunoelectron microscopy|N-terminal animo acid sequencing 2008 Filtration|Diafiltration|Gel filtration Exosomes 65 19415654 Homo sapiens Proteomics of MUC1-containing lipid rafts from plasma membranes and exosomes of human breast carcinoma cells MCF-7. Breast cancer cells cl MCF-7 Protein Mass spectrometry [MALDI TOF]|Western blotting 2009 Differential centrifugation|Sucrose density gradient Exosomes 66 19199708 Homo sapiens Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT). Saliva ts Saliva Protein Mass spectrometry [LTQ]|Western blotting|Immunoelectron microscopy 2009 Differential centrifugation Exosomes 67 19619303 Homo sapiens Claudin-containing exosomes in the peripheral circulation of women with ovarian cancer. Ovarian cancer cells cl BG-1 Protein Western blotting|Immunoelectron microscopy 2009 Differential centrifugation|Sucrose density gradient Exosomes 68 19619303 Homo sapiens Claudin-containing exosomes in the peripheral circulation of women with ovarian cancer. Plasma ts Plasma - Ovarian cancer Protein Western blotting 2009 Differential centrifugation Exosomes 69 19812188 Rattus norvegicus Immature dendritic cell-derived exosomes rescue septic animals via milk fat globule epidermal growth factor VIII. Dendritic cells cl Bone marrow-derived immature dendritic cells Protein Western blotting 2009 Differential centrifugation|Sucrose density gradient Exosomes 70 19812188 Rattus norvegicus Immature dendritic cell-derived exosomes rescue septic animals via milk fat globule epidermal growth factor VIII. Dendritic cells cl Bone marrow-derived mature dendritic cells Protein Western blotting 2009 Differential centrifugation Exosomes 71 19801663 Homo sapiens Microenvironmental pH is a key factor for exosome traffic in tumor cells. Melanoma cells cl Mel1 Protein|Lipids Western blotting|Thin layer chromatography 2009 Differential centrifugation|Sucrose density gradient Exosomes 72 19801663 Homo sapiens Microenvironmental pH is a key factor for exosome traffic in tumor cells. Melanoma cells cl Me665/1 Protein|Lipids Western blotting|Thin layer chromatography 2009 Differential centrifugation Exosomes 73 18494037 Mus musculus Difference gel electrophoresis analysis of Ras-transformed fibroblast cell-derived exosomes. Embryonic fibroblasts cl NIH3T3 Protein Mass spectrometry [LCQ DECA]|Western blotting 2008 Differential centrifugation Exosomes 74 19381331 Homo sapiens High levels of exosomes expressing CD63 and caveolin-1 in plasma of melanoma patients. Melanoma cells cl Me501 Protein Western blotting|ELISA|FACS 2009 Differential centrifugation Exosomes 75 19381331 Homo sapiens High levels of exosomes expressing CD63 and caveolin-1 in plasma of melanoma patients. Plasma ts Plasma - melanoma Protein Western blotting|ELISA|FACS 2009 Differential centrifugation Exosomes 76 20224111 Homo sapiens Proteomics analysis of bladder cancer exosomes. Bladder cancer cells cl HT1376 Protein Mass spectrometry [MALDI TOF/TOF]|Western blotting|FACS 2010 Differential centrifugation|Sucrose density gradient Exosomes 77 20224111 Homo sapiens Proteomics analysis of bladder cancer exosomes. Urine ts Urine - Normal Protein FACS 2010 Differential centrifugation|Sucrose density gradient Exosomes 78 20224111 Homo sapiens Proteomics analysis of bladder cancer exosomes. Urine ts Urine - Prostate cancer Protein FACS 2010 Differential centrifugation|Sucrose density gradient Exosomes 79 20458337 Homo sapiens MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 1 B cells cl RN (HLA-DR15) Protein Mass spectrometry [FT-ICR]|Western blotting 2010 Differential centrifugation|Sucrose density gradient|Immunobeads (MHC Class II) Exosomes 80 20458337 Homo sapiens MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis -Sample 2 B cells cl RN (HLA-DR15) Protein Mass spectrometry [FT-ICR]|Western blotting 2010 Differential centrifugation|Sucrose density gradient|Immunobeads (MHC Class II) Exosomes 81 20458337 Homo sapiens MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 3 B cells cl RN (HLA-DR15) Protein Mass spectrometry [FT-ICR]|Western blotting 2010 Differential centrifugation|Sucrose density gradient|Immunobeads (MHC Class II) Exosomes 82 20949044 Homo sapiens Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line Stomach cancer cells cl AZ-521 Protein|miRNA Western blotting|RT-PCR|Human miRNA Microarray Kit 2010 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 83 20949044 Homo sapiens Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line Lung cancer cells cl SBC-3 Protein|miRNA Western blotting|RT-PCR|Human miRNA Microarray Kit 2010 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 84 20949044 Homo sapiens Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line Lung cancer cells cl DMS-53 miRNA Human miRNA Microarray Kit|RT-PCR 2010 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 85 20949044 Homo sapiens Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line Lung cancer cells cl NCI-H69 miRNA Human miRNA Microarray Kit|RT-PCR 2010 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 86 20949044 Homo sapiens Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line Colorectal cancer cells cl SW480 miRNA Human miRNA Microarray Kit|RT-PCR 2010 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 87 20949044 Homo sapiens Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line Colorectal cancer cells cl SW620 miRNA RT-PCR 2010 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 88 20949044 Homo sapiens Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line Stomach cancer cells cl AZ-P7a Protein|miRNA Immunoelectron microscopy|Western blotting|RT-PCR|Human miRNA Microarray Kit 2010 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 89 20424270 Rattus norvegicus Exosomes account for vesicle-mediated transcellular transport of activatable phospholipases and prostaglandins. Basophilic leukemia cells cl RBL-2H3 Protein|Lipids Western blotting|Gas chromatography|Thin layer chromatography|Mass spectrometry [Qstar XL]|FACS 2010 Differential centrifugation|Sucrose density gradient Exosomes 90 21828046 Rattus norvegicus The proteo-lipidic composition of exosomes changes during reticulocyte maturation. Reticulocytes ts Reticulocytes - D2 Rep 1 Protein|Lipids Mass spectrometry [QSTAR]|Mass spectrometry [Orbitrap]|Western blotting 2011 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 91 21252909 Homo sapiens Diacylglycerol kinase a regulates the formation and polarisation of mature multivesicular bodies involved in the secretion of Fas ligand-containing exosomes in T lymphocytes T cells cl J-HM1-2.2 Protein|Lipids Western blotting|FACS|Immunofluorescent microscopy 2011 Differential centrifugation|Ultracentrifugation Exosomes 92 20124479 Rattus norvegicus Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation. Pancreatic cancer cells cl AS Protein|mRNA RT-PCR|Western blotting|RatRef-12 Microarray|FACS|Mass spectrometry [MALDI TOF] 2010 Differential centrifugation|Sucrose density gradient Exosomes 93 20124479 Rattus norvegicus Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation. Pancreatic cancer cells cl AS-Tspan8 Protein|mRNA RT-PCR|Western blotting 2010 Differential centrifugation|Sucrose density gradient Exosomes 94 21828046 Rattus norvegicus The proteo-lipidic composition of exosomes changes during reticulocyte maturation. Reticulocytes ts Reticulocytes - D4 Rep 1 Protein|Lipids Mass spectrometry [QSTAR]|Mass spectrometry [Orbitrap]|Western blotting 2011 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 95 21828046 Rattus norvegicus The proteo-lipidic composition of exosomes changes during reticulocyte maturation. Reticulocytes ts Reticulocytes - D7 Rep 1 Protein|Lipids Mass spectrometry [QSTAR]|Mass spectrometry [Orbitrap]|Western blotting 2011 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 96 21828046 Rattus norvegicus The proteo-lipidic composition of exosomes changes during reticulocyte maturation. Reticulocytes ts Reticulocytes - D2 Rep 2 Protein|Lipids Mass spectrometry [QSTAR]|Mass spectrometry [Orbitrap]|Western blotting 2011 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 97 21828046 Rattus norvegicus The proteo-lipidic composition of exosomes changes during reticulocyte maturation. Reticulocytes ts Reticulocytes - D4 Rep 2 Protein|Lipids Mass spectrometry [QSTAR]|Mass spectrometry [Orbitrap]|Western blotting 2011 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 98 21828046 Rattus norvegicus The proteo-lipidic composition of exosomes changes during reticulocyte maturation. Reticulocytes ts Reticulocytes - D7 Rep 2 Protein|Lipids Mass spectrometry [QSTAR]|Mass spectrometry [Orbitrap]|Western blotting 2011 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 99 21828046 Rattus norvegicus The proteo-lipidic composition of exosomes changes during reticulocyte maturation. Reticulocytes ts Reticulocytes - D2 Rep 3 Protein|Lipids Mass spectrometry [QSTAR]|Mass spectrometry [Orbitrap]|Western blotting 2011 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 100 21828046 Rattus norvegicus The proteo-lipidic composition of exosomes changes during reticulocyte maturation. Reticulocytes ts Reticulocytes - D4 Rep 3 Protein|Lipids Mass spectrometry [QSTAR]|Mass spectrometry [Orbitrap]|Western blotting 2011 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 101 21828046 Rattus norvegicus The proteo-lipidic composition of exosomes changes during reticulocyte maturation. Reticulocytes ts Reticulocytes - D7 Rep 3 Protein|Lipids Mass spectrometry [QSTAR]|Mass spectrometry [Orbitrap]|Western blotting 2011 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 102 21082674 Homo sapiens Comprehensive analysis of low-abundance proteins in human urinary exosomes using peptide ligand library technology, peptide OFFGEL fractionation and nanoHPLC-chip-MS/MS. Urine ts Urine - Normal Protein Mass spectrometry|Western blotting|Immunoelectron microscopy 2010 Differential centrifugation|Ultracentrifugation Exosomes 103 21763319 Homo sapiens Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells. Pancreatic cancer cells cl Panc1 Protein Mass spectrometry [Orbitrap]|Western blotting 2011 Differential centrifugation|Filtration|Ultrafiltration|Ultracentrifugation Exosomes 104 21763319 Homo sapiens Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells. Pancreatic cancer cells cl BxPC3 Protein Western blotting 2011 Differential centrifugation|Filtration|Ultrafiltration|Ultracentrifugation Exosomes 105 21763319 Homo sapiens Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells. Pancreatic cancer cells cl Paca44 Protein Western blotting 2011 Differential centrifugation|Filtration|Ultrafiltration|Ultracentrifugation Exosomes 106 21763319 Homo sapiens Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells. Pancreatic cancer cells cl MiaPaca2 Protein Western blotting 2011 Differential centrifugation|Filtration|Ultrafiltration|Ultracentrifugation Exosomes 107 21763319 Homo sapiens Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells. Pancreatic cancer cells cl A818-4 Protein Western blotting 2011 Differential centrifugation|Filtration|Ultrafiltration|Ultracentrifugation Exosomes 108 21601258 Homo sapiens Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage. Ascites ts Malignant ascites - ovarian cancer Protein|miRNA Western blotting|Immunoelectron microscopy 2011 Differential centrifugation|Sucrose density gradient|Immunobeads (EpCAM, CD24) Exosomes 109 21601258 Homo sapiens Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage. Malignant pleural effusions ts Pleural effusions - breast cancer Protein|miRNA Western blotting 2011 Differential centrifugation|Sucrose density gradient|Immunobeads (EpCAM) Exosomes 110 21601258 Homo sapiens Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage. Ascites ts Ascites - liver cirrhosis Protein|miRNA Western blotting|Immunoelectron microscopy 2011 Differential centrifugation|Sucrose density gradient Exosomes 111 21601258 Homo sapiens Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage. Serum ts Serum - breast cancer Protein|miRNA Western blotting 2011 Differential centrifugation|Sucrose density gradient|Immunobeads (CD24) Exosomes 112 21601258 Homo sapiens Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage. Serum ts Serum - Normal Protein|miRNA Western blotting 2011 Differential centrifugation|Sucrose density gradient Exosomes 113 21557262 Homo sapiens Proteomic identification of exosomal LRG1: A potential urinary biomarker for detecting NSCLC. Urine ts Urine - Normal Protein Mass spectrometry|Western blotting 2011 Differential centrifugation|Ultracentrifugation Exosomes 114 21557262 Homo sapiens Proteomic identification of exosomal LRG1: A potential urinary biomarker for detecting NSCLC. Urine ts Urine - Lung cancer Protein Mass spectrometry|Western blotting 2011 Differential centrifugation|Ultracentrifugation Exosomes 115 21505438 Homo sapiens Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells. T cells cl J77 Protein|miRNA Mass spectrometry|Microarray 2011 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 116 21505438 Homo sapiens Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells. B cells cl Raji Protein|miRNA Mass spectrometry|Microarray 2011 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 117 21505438 Homo sapiens Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells. Dendritic cells ts Dendritic cells Protein|miRNA Mass spectrometry|Microarray 2011 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 118 21362503 Homo sapiens Protein profile of exosomes from trabecular meshwork cells. Tabecular meshwork cells ts Tabecular meshwork cells Protein Mass spectrometry [LTQ]|Western blotting 2011 Differential centrifugation|Sucrose density gradient Exosomes 119 21362503 Homo sapiens Protein profile of exosomes from trabecular meshwork cells. Urine ts Urine - Normal Protein Mass spectrometry [LTQ]|Western blotting 2011 Differential centrifugation|Sucrose density gradient Exosomes 120 21362503 Homo sapiens Protein profile of exosomes from trabecular meshwork cells. Aqueous humor ts Aqueous humor - Normal Protein Western blotting 2011 Differential centrifugation|Sucrose density gradient Exosomes 121 21276792 Homo sapiens Morphologic and proteomic characterization of exosomes released by cultured extravillous trophoblast cells. Trophoblast cells cl Sw71 Protein Mass spectrometry [Orbitrap]|Western blotting 2011 Differential centrifugation|Ultrafiltration|Ultracentrifugation|Density gradient centrifugation Exosomes 122 21235781 Homo sapiens Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages. Saliva ts Saliva - Normal Protein FACS|Immunoelectron microscopy|Western blotting 2011 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 123 21235781 Homo sapiens Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages. Plasma ts Plasma - Normal Protein FACS|Immunoelectron microscopy|Western blotting 2011 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 124 21235781 Homo sapiens Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages. Breast milk ts Breast milk - normal Protein FACS|Immunoelectron microscopy|Western blotting 2011 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 125 21059916 Homo sapiens Human tumor virus utilizes exosomes for intercellular communication. Nasopharyngeal carcinoma cells cl C666 Protein Western blotting 2010 Differential centrifugation Exosomes 126 0 Homo sapiens Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy? Mesenchymal stem cells cl huES9.E1 Protein Western blotting|Antibody array|Mass spectrometry 2011 HPLC Exosomes 127 21828046 Rattus norvegicus Proteolipidic Composition of Exosomes Changes during Reticulocyte Maturation Reticulocytes ts Reticulocytes Protein|Lipids Gas chromatography|High performance thin layer chromatography 2011 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 128 14965343 Homo sapiens Mast cell- and dendritic cell-derived exosomes display a specific lipid composition and an unusual membrane organization Dendritic cells ts Bone marrow - Dendritic cells Lipids High performance liquid chromatography|Gas chromatography 2004 Differential centrifugation|Ultracentrifugation Exosomes 129 14965343 Rattus norvegicus Mast cell- and dendritic cell-derived exosomes display a specific lipid composition and an unusual membrane organization Tumoral mast cells cl RBL-2H3 Lipids High performance liquid chromatography|Gas chromatography 2004 Differential centrifugation|Ultracentrifugation Exosomes 130 18309083 Mus musculus Ceramide triggers budding of exosome vesicles into multivesicular endosomes Oligodendrocytes cl Oli-neu cells Protein|Lipids Western blotting|Mass spectrometry[QTOF] 2008 Differential centrifugation|Sucrose density gradient Exosomes 131 19188015 Homo sapiens Systemic presence and tumor-growth promoting effect of ovarian carcinoma released exosomes Ascites ts Malignant ascites - Ovarian cancer Protein|Lipids Cytofluorographic analysis|Annexin V-FITC|Western blotting|FACS 2009 Differential centrifugation|Sucrose density gradient Exosomes 132 19188015 Homo sapiens Systemic presence and tumor-growth promoting effect of ovarian carcinoma released exosomes Ovarian cancer cells cl OVMz Protein|Lipids Cytofluorographic analysis|Annexin V-FITC|FACS 2009 Differential centrifugation|Sucrose density gradient Exosomes 133 19188015 Homo sapiens Systemic presence and tumor-growth promoting effect of ovarian carcinoma released exosomes Ovarian cancer cells cl SKOV3ip Protein|Lipids Cytofluorographic analysis|Annexin V-FITC|FACS 2009 Differential centrifugation|Sucrose density gradient Exosomes 134 15304316 Rattus norvegicus PLD2 is enriched on exosomes and its activity is correlated to the release of exosomes Basophilic leukemia cells cl RBL-2H3 Protein|Lipids Western blotting|FACS 2004 Differential centrifugation Exosomes 135 2777884 Cavia porcellus Asymmetric Distribution of Phospholipids in the Membrane of Vesicles Released During In Vitro Maturation of Guinea Pig Reticulocytes: Evidence Precluding a Role for Aminophospholipid Translocase Reticulocytes ts Reticulocytes - Normal Proteins|Lipids Immunoelectron microscopy|Thin layer chromatography|Western blotting 1989 Differential centrifugation|Ultracentrifugation Exosomes 136 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells cl PC3 - Rep 2 Protein Mass spectrometry [QTOF] 2012 Sucrose density gradient Exosomes 137 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells cl PC3 - Rep 3 Protein Mass spectrometry [QTOF] 2012 Sucrose density gradient Exosomes 138 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells cl DU145 - Rep 2 Protein Mass spectrometry [QTOF] 2012 Sucrose density gradient Exosomes 139 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells cl DU145 - Rep 3 Protein Mass spectrometry [QTOF] 2012 Sucrose density gradient Exosomes 140 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells cl VCaP - Rep 2 Protein Mass spectrometry [QTOF] 2012 Sucrose density gradient Exosomes 141 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells cl VCaP - Rep 3 Protein Mass spectrometry [QTOF] 2012 Sucrose density gradient Exosomes 142 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells cl LNCaP - Rep 2 Protein Mass spectrometry [QTOF] 2012 Sucrose density gradient Exosomes 143 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells cl LNCaP - Rep 3 Protein Mass spectrometry [QTOF] 2012 Sucrose density gradient Exosomes 144 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells cl C4-2 - Rep 2 Protein Mass spectrometry [QTOF] 2012 Sucrose density gradient Exosomes 145 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells cl C4-2 - Rep 3 Protein Mass spectrometry [QTOF] 2012 Sucrose density gradient Exosomes 146 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells cl RWPE - Rep 2 Protein Mass spectrometry [QTOF] 2012 Sucrose density gradient Exosomes 151 22075275 Homo sapiens Methodology for isolation, identification and characterization of microvesicles in peripheral blood Plasma ts Plasma - Normal Protein FACS 2011 Differential centrifugation|Filtration|Ultracentrifugation Microvesicles 152 22064971 Homo sapiens Oxidized low-density lipoprotein-dependent platelet-derived microvesicles trigger procoagulant effects and amplify oxidative stress Platelets ts Platelets Protein FACS|ELISA 2011 Differential centrifugation Microvesicles 153 22022598 Homo sapiens Syncytiotrophoblast microvesicles released from pre-eclampsia placentae exhibit increased tissue factor activity Placenta ts Placenta Protein FACS 2011 Differential centrifugation Microvesicles 154 21966536 Mus musculus Leukocyte- and platelet-derived microvesicle interactions following in vitro and in vivo activation of toll-like receptor 4 by lipopolysaccharide Plasma ts Plasma - Normal Protein FACS 2011 Differential centrifugation|Filtration Microvesicles 155 21939504 Homo sapiens Microvesicles secreted by macrophages shuttle invasion-potentiating microRNAs into breast cancer cells Macrophage ts Macrophages - Unactivated miRNA RT-PCR 2011 Differential centrifugation|Filtration|Ultracentrifugation Microvesicles 156 21939504 Homo sapiens Microvesicles secreted by macrophages shuttle invasion-potentiating microRNAs into breast cancer cells Macrophage ts Macrophages - IL-4 activated miRNA RT-PCR 2011 Differential centrifugation|Filtration|Ultracentrifugation Microvesicles 157 21630462 Homo sapiens Proteomic analysis of microvesicles derived from human colorectal cancer ascites Ascites ts Malignant ascites - Colorectal cancer patient 1 Protein Mass spectrometry [LTQ] 2011 Differential centrifugation|Sucrose density gradient|OptiPrep density gradient Microvesicles 158 21630462 Homo sapiens Proteomic analysis of microvesicles derived from human colorectal cancer ascites Ascites ts Malignant ascites - Colorectal cancer patient 2 Protein Mass spectrometry [LTQ] 2011 Differential centrifugation|Sucrose density gradient|OptiPrep density gradient Microvesicles 159 21630462 Homo sapiens Proteomic analysis of microvesicles derived from human colorectal cancer ascites Ascites ts Malignant ascites - Colorectal cancer patient 3 Protein Mass spectrometry [LTQ] 2011 Differential centrifugation|Sucrose density gradient|OptiPrep density gradient Microvesicles 160 21630462 Homo sapiens Proteomic analysis of microvesicles derived from human colorectal cancer ascites Ascites ts Malignant ascites - Colorectal cancer Protein Western blotting 2011 Differential centrifugation|Sucrose density gradient|OptiPrep density gradient Microvesicles 161 21901833 Drosophila melanogaster Proteomics analyses of microvesicles released by Drosophila Kc167 and S2 cells Hematocytes cl Kc167 Protein|PTM Ubiquitination Western blotting|Mass spectrometry [HCT ETD II iontrap] 2011 Differential centrifugation|Sucrose density gradient|Ultracentrifugation Microvesicles 162 21901833 Drosophila melanogaster Proteomics analyses of microvesicles released by Drosophila Kc167 and S2 cells Hematocytes cl S2 Protein|PTM Ubiquitination Western blotting|Mass spectrometry [HCT ETD II iontrap] 2011 Differential centrifugation|Sucrose density gradient|Ultracentrifugation Microvesicles 163 21901833 Drosophila melanogaster Proteomics analyses of microvesicles released by Drosophila Kc167 and S2 cells Hematocytes cl S2-tub-wg Protein Western blotting|Immunoelectron microscopy 2011 Differential centrifugation|Sucrose density gradient|Ultracentrifugation Microvesicles 164 21864488 Homo sapiens Marrow cell genetic phenotype change induced by human lung cancer cells Lung cancer cells ts Lung cancer cells - patient 1 mRNA RT-PCR 2011 Differential centrifugation|Ultracentrifugation Microvesicles 165 21864488 Homo sapiens Marrow cell genetic phenotype change induced by human lung cancer cells Lung cancer cells ts Lung cancer cells - patient 2 mRNA RT-PCR 2011 Differential centrifugation|Ultracentrifugation Microvesicles 166 21864488 Homo sapiens Marrow cell genetic phenotype change induced by human lung cancer cells Lung cancer cells ts Lung cancer cells - patient 3 mRNA RT-PCR 2011 Differential centrifugation|Ultracentrifugation Microvesicles 167 21859146 Homo sapiens Identification of a conserved glycan signature for microvesicles T cells cl Jurkat Protein Western blotting 2011 Differential centrifugation|Filtration|Ultracentrifugation Microvesicles 168 21859146 Homo sapiens Identification of a conserved glycan signature for microvesicles T cells cl SupT1 Protein Western blotting 2011 Differential centrifugation|Filtration|Ultracentrifugation Microvesicles 169 21859146 Homo sapiens Identification of a conserved glycan signature for microvesicles T cells cl H9 Protein Western blotting 2011 Differential centrifugation|Filtration|Ultracentrifugation Microvesicles 170 21859146 Homo sapiens Identification of a conserved glycan signature for microvesicles Colorectal cancer cells cl HCT-15 Protein Western blotting 2011 Differential centrifugation|Filtration|Ultracentrifugation Microvesicles 171 21859146 Homo sapiens Identification of a conserved glycan signature for microvesicles Colorectal cancer cells cl HT-29 Protein Western blotting 2011 Differential centrifugation|Filtration|Ultracentrifugation Microvesicles 172 21859146 Homo sapiens Identification of a conserved glycan signature for microvesicles Melanoma cells cl SkMel-5 Protein Western blotting 2011 Differential centrifugation|Filtration|Ultracentrifugation Microvesicles 173 21859146 Homo sapiens Identification of a conserved glycan signature for microvesicles Breast milk ts Breast milk - normal Protein Western blotting 2011 Differential centrifugation|Filtration|Ultracentrifugation Microvesicles 174 21842121 Mus musculus Oligodendroglioma cells shed microvesicles which contain TRAIL as well as molecular chaperones and induce cell death in astrocytes Oligodendrocytes cl G26/24 Protein Western blotting 2011 Differential centrifugation Microvesicles 175 19002258 Homo sapiens Detection of microRNA Expression in Human Peripheral Blood Microvesicles Plasma ts Plasma - Normal miRNA RT-PCR 2008 Differential centrifugation Microvesicles 176 21788507 Homo sapiens Hypoxia triggers a proangiogenic pathway involving cancer cell microvesicles and PAR-2-mediated heparin-binding EGF signaling in endothelial cells Glioblastoma cells cl U87-MG Protein Immunoelectron microscopy|Western blotting 2011 Differential centrifugation Microvesicles 177 19567368 Homo sapiens Proteomics characterization of cell membrane blebs in human retinal pigment epithelium cells Epithelial cells cl ARPE-19 (Retinal epithelial cells) Protein Western blotting|Mass spectrometry [LTQ-FT Ultra] 2009 Differential centrifugation Membrane blebs 178 20686450 Homo sapiens Comparison of three methods for isolation of urinary microvesicles to identify biomarkers of nephrotic syndrome Urine ts Urine - NM UF Protein Western blotting|Mass spectrometry [MALDI TOF] 2010 Differential centrifugation|Ultrafiltration Microvesicles 179 20686450 Homo sapiens Comparison of three methods for isolation of urinary microvesicles to identify biomarkers of nephrotic syndrome Urine ts Urine - UC Protein Western blotting|Mass spectrometry [MALDI TOF] 2010 Differential centrifugation|Ultracentrifugation Microvesicles 180 20686450 Homo sapiens Comparison of three methods for isolation of urinary microvesicles to identify biomarkers of nephrotic syndrome Urine ts Urine - SEC Protein Western blotting|Mass spectrometry [MALDI TOF] 2010 Differential centrifugation|Ultracentrifugation|Size exclusion chromatography|Filtration Microvesicles 181 20668554 Homo sapiens Microvesicles derived from adult human bone marrow and tissue specific mesenchymal stem cells shuttle selected pattern of miRNAs Mesenchymal stem cells ts Mesenchymal stem cells - Normal Protein|miRNA Western blotting|RT-PCR|Immunogold|Immunoelectron microscopy 2010 Differential centrifugation|Ultracentrifugation Microvesicles 182 20668554 Homo sapiens Microvesicles derived from adult human bone marrow and tissue specific mesenchymal stem cells shuttle selected pattern of miRNAs Liver stem cells ts Liver stem cells - Normal miRNA Western blotting|RT-PCR|Immunogold|Immunoelectron microscopy 2010 Differential centrifugation|Ultracentrifugation Microvesicles 183 21741384 Homo sapiens A filtration-based protocol to isolate human plasma membrane-derived vesicles and exosomes from blood plasma Plasma ts Plasma - Normal Protein FACS|ELISA 2011 Differential centrifugation|Filtration Microvesicles 184 21672581 Rattus norvegicus Oxygen-glucose deprivation increases the enzymatic activity and the microvesicle-mediated release of ectonucleotidases in the cells composing the blood-brain barrier Astrocytes ts Astrocytes - Normal Protein Immunoelectron microscopy 2011 Differential centrifugation Microvesicles 185 22116803 Equus caballus Cell-Secreted Vesicles in Equine Ovarian Follicular Fluid Contain miRNAs and Proteins: A Possible New Form of Cell Communication Within the Ovarian Follicle Follicular fluid ts Follicular fluid - Ovarian - Young mare Protein|miRNA Western blotting|RT-PCR|Mass spectrometry [LTQ] 2011 Differential centrifugation|ExoQuick Exosomes 186 22116803 Equus caballus Cell-Secreted Vesicles in Equine Ovarian Follicular Fluid Contain miRNAs and Proteins: A Possible New Form of Cell Communication Within the Ovarian Follicle Follicular fluid ts Follicular fluid - Ovarian Protein|miRNA RT-PCR|FACS 2011 Differential centrifugation|Ultracentrifugation Microvesicles 187 22116803 Equus caballus Cell-Secreted Vesicles in Equine Ovarian Follicular Fluid Contain miRNAs and Proteins: A Possible New Form of Cell Communication Within the Ovarian Follicle Serum ts Serum - Normal Protein FACS 2011 Differential centrifugation|ExoQuick Exosomes 189 21741384 Homo sapiens A filtration-based protocol to isolate human plasma membrane-derived vesicles and exosomes from blood plasma Plasma ts Plasma - Normal Protein FACS|ELISA 2011 Differential centrifugation|Filtration Exosomes 190 22116803 Equus caballus Cell-Secreted Vesicles in Equine Ovarian Follicular Fluid Contain miRNAs and Proteins: A Possible New Form of Cell Communication Within the Ovarian Follicle Follicular fluid ts Follicular fluid - Ovarian - Old mare miRNA RT-PCR 2011 Differential centrifugation|ExoQuick Exosomes 191 21635979 Mus musculus Proteomic characterization of thymocyte-derived microvesicles and apoptotic bodies in BALB/c mice Thymus ts Thymocytes - Normal Protein Western blotting|FACS|Mass spectrometry [QTOF] 2011 Differential centrifugation|Filtration Microvesicles 192 21635979 Mus musculus Proteomic characterization of thymocyte-derived microvesicles and apoptotic bodies in BALB/c mice Thymus ts Thymocytes - Normal Protein Western blotting|FACS|Mass spectrometry [QTOF] 2011 Differential centrifugation|Filtration Apoptotic bodies 193 21575145 Homo sapiens Microvesicle-mediated release of soluble LH/hCG receptor (LHCGR) from transfected cells and placenta explants Placenta ts Placenta - Normal Protein Western blotting 2011 Differential centrifugation|Ultracentrifugation Microvesicles 195 21668449 Mus musculus SV31 is a Zn2+-binding synaptic vesicle protein Pheochromocytoma cells ts PC12 cells Protein Western blotting 2011 Differential centrifugation|Sucrose density gradient Large dense core vesicles 196 21668449 Mus musculus SV31 is a Zn2+-binding synaptic vesicle protein Pheochromocytoma cells ts PC12 cells - Transfected Protein Western blotting 2011 Differential centrifugation|Sucrose density gradient Large dense core vesicles 197 21616097 Homo sapiens Release of podocalyxin into the extracellular space. Role of metalloproteinases Testicular cancer cells cl Tera-1 Protein Western blotting 2011 Differential centrifugation Microvesicles 198 21555566 Homo sapiens Multiple recognition assay reveals prostasomes as promising plasma biomarkers for prostate cancer Plasma ts Plasma - Prostate cancer Protein Proximity ligation assay 2011 Differential centrifugation|Ultracentrifugation|Gel chromatography Microvesicles 199 21609964 Homo sapiens Characterization of extracellular circulating microRNA Plasma ts Plasma - Normal Protein Western blotting 2011 Differential centrifugation|Filtration Exosomes 200 21606166 Homo sapiens Blast-derived microvesicles in sera from patients with acute myeloid leukemia suppress natural killer cell function via membrane-associated transforming growth factor-beta1 Serum ts Serum - Normal Protein Western blotting|FACS 2011 Size exclusion chromatography|Ultracentrifugation Microvesicles 201 21606166 Homo sapiens Blast-derived microvesicles in sera from patients with acute myeloid leukemia suppress natural killer cell function via membrane-associated transforming growth factor-beta2 Serum ts Serum - Acute myeloid leukemia Protein Western blotting|FACS 2011 Size exclusion chromatography|Ultracentrifugation Microvesicles 202 21601655 Homo sapiens Sizing and phenotyping of cellular vesicles using Nanoparticle Tracking Analysis Placenta ts Placenta - Normal Protein FACS|Immunoelectron microscopy 2011 Differential centrifugation|Ultracentrifugation Microvesicles 203 19011622 Homo sapiens Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers Glioblastoma cells ts Glioblastoma cells Protein|miRNA|mRNA RT-PCR|Antibody array|Microarray 2008 Differential centrifugation|Ultracentrifugation|Filtration Microvesicles 204 19011622 Homo sapiens Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers Serum ts Serum - Normal mRNA|miRNA RT-PCR 2008 Differential centrifugation|Ultracentrifugation|Filtration Microvesicles 205 19011622 Homo sapiens Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers Serum ts Serum - Glioblastoma mRNA|miRNA RT-PCR 2008 Differential centrifugation|Ultracentrifugation|Filtration Microvesicles 206 21435393 Rattus norvegicus Microvesicles released from rat adipocytes and harboring glycosylphosphatidylinositol-anchored proteins transfer RNA stimulating lipid synthesis Adipocytes ts Adipocytes - Large mRNA|miRNA RT-PCR 2011 Differential centrifugation|Immunobeads (Gce1/CD73) Microvesicles 207 21435393 Rattus norvegicus Microvesicles released from rat adipocytes and harboring glycosylphosphatidylinositol-anchored proteins transfer RNA stimulating lipid synthesis Adipocytes ts Stromal vascular cells - Differentiated adipocytes mRNA|miRNA RT-PCR 2011 Differential centrifugation|Sucrose density gradient|Size exclusion chromatography Microvesicles 208 21435393 Rattus norvegicus Microvesicles released from rat adipocytes and harboring glycosylphosphatidylinositol-anchored proteins transfer RNA stimulating lipid synthesis Serum ts Serum - Normal mRNA|miRNA RT-PCR 2011 Differential centrifugation|Sucrose density gradient|Immunobeads (Gce1/CD73) Microvesicles 209 21435393 Rattus norvegicus Microvesicles released from rat adipocytes and harboring glycosylphosphatidylinositol-anchored proteins transfer RNA stimulating lipid synthesis Adipocytes ts Adipocytes - Small mRNA|miRNA RT-PCR 2011 Differential centrifugation|Immunobeads (Gce1/CD73) Microvesicles 210 21368175 Homo sapiens Cancer cell-derived microvesicles induce transformation by transferring tissue transglutaminase and fibronectin to recipient cells Breast cancer cells cl MDA-MB-231 Protein Western blotting|Immunofluorescent microscopy|Scanning electron microscopy|Mass spectrometry [4000 Q Trap] 2011 Differential centrifugation|Filtration Microvesicles 211 21368175 Homo sapiens Cancer cell-derived microvesicles induce transformation by transferring tissue transglutaminase and fibronectin to recipient cells Glioma cells cl U87 Protein Western blotting|Mass spectrometry [4000 Q Trap] 2011 Differential centrifugation|Filtration Microvesicles 212 21372807 Rattus norvegicus Upregulation of lipid synthesis in small rat adipocytes by microvesicle-associated CD73 from large adipocytes Adipocytes ts Adipocytes - Large Protein Western blotting 2011 Differential centrifugation Microvesicles 213 21372807 Rattus norvegicus Upregulation of lipid synthesis in small rat adipocytes by microvesicle-associated CD73 from large adipocytes Adipocytes ts Adipocytes - Small Protein Western blotting 2011 Differential centrifugation Microvesicles 214 21364924 Homo sapiens Thermal- and oxidative stress causes enhanced release of NKG2D ligand-bearing immunosuppressive exosomes in leukemia/lymphoma T and B cells T cells cl Jurkat Protein Western blotting|Immunoelectron microscopy|FACS 2011 Differential centrifugation|Ultracentrifugation|Filtration|Sucrose density gradient|FACS Exosomes 215 21364924 Homo sapiens Thermal- and oxidative stress causes enhanced release of NKG2D ligand-bearing immunosuppressive exosomes in leukemia/lymphoma T and B cells B cells cl Raji Protein Western blotting|Immunoelectron microscopy|FACS 2011 Differential centrifugation|Ultracentrifugation|Filtration|Sucrose density gradient|FACS Exosomes 216 21293856 Homo sapiens Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC Breast cancer cells cl BT474 Protein Western blotting|Immunoelectron microscopy|FACS|Dot blot 2011 Differential centrifugation|Filtration|Ultrafiltration|Ultracentrifugation|Sucrose density gradient Exosomes 217 21293856 Homo sapiens Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC Serum ts Serum - Breast cancer Protein ELISA|Dot blot 2011 Differential centrifugation|Filtration|Ultrafiltration|Ultracentrifugation|Sucrose density gradient Exosomes 218 10694520 Homo sapiens Elevated levels of shed membrane microparticles with procoagulant potential in the peripheral circulating blood of patients with acute coronary syndromes Plasma ts Plasma - Stable angina Protein Immunoaffinity 2000 Immunoaffinity [Annexin-V] Microparticles 219 10694520 Homo sapiens Elevated levels of shed membrane microparticles with procoagulant potential in the peripheral circulating blood of patients with acute coronary syndromes Plasma ts Plasma - Acute coronary syndromes Protein Immunoaffinity 2000 Immunoaffinity [Annexin-V] Microparticles 220 10694520 Homo sapiens Elevated levels of shed membrane microparticles with procoagulant potential in the peripheral circulating blood of patients with acute coronary syndromes Plasma ts Plasma - Noncoronary heart disease Protein Immunoaffinity 2000 Immunoaffinity [Annexin-V] Microparticles 221 9918520 Homo sapiens Shed membrane microparticles with procoagulant potential in human atherosclerotic plaques: a role for apoptosis in plaque thrombogenicity Atherosclerotic plaques ts Atherosclerotic plaques Protein|Lipids Immunohistochemistry|Immunoaffinity 1999 Differential centrifugation|Immunoaffinity [Annexin-V] Apoptotic bodies 222 12514112 Homo sapiens Intravascular tissue factor initiates coagulation via circulating microvesicles and platelets Plasma ts Plasma - Normal Protein Immunoelectron microscopy|FACS|Western blotting 2003 Differential centrifugation|FACS Microvesicles 223 10393703 Homo sapiens In vitro generation of endothelial microparticles and possible prothrombotic activity in patients with lupus anticoagulant Endothelial cells cl HUVECS Protein FACS|Western blotting 1999 Differential centrifugation|Ultracentrifugation Microparticles 224 10393703 Homo sapiens In vitro generation of endothelial microparticles and possible prothrombotic activity in patients with lupus anticoagulant Plasma ts Plasma - Normal Protein Confocal microscopy|FACS 1999 Differential centrifugation Microparticles 225 10393703 Homo sapiens In vitro generation of endothelial microparticles and possible prothrombotic activity in patients with lupus anticoagulant Plasma ts Plasma - Lupus anticoagulant Protein FACS 1999 Differential centrifugation Microparticles 226 12514112 Homo sapiens Intravascular tissue factor initiates coagulation via circulating microvesicles and platelets Platelets ts Platelets Protein Western blotting 2003 Differential centrifugation Microvesicles 227 2942561 Homo sapiens Platelet surface glycoproteins. Studies on resting and activated platelets and platelet membrane microparticles in normal subjects, and observations in patients during adult respiratory distress syndrome and cardiac surgery Plasma ts Plasma - Normal Protein Antibody based methods 1986 Differential centrifugation Microparticles 228 2942561 Homo sapiens Platelet surface glycoproteins. Studies on resting and activated platelets and platelet membrane microparticles in normal subjects, and observations in patients during adult respiratory distress syndrome and cardiac surgery Serum ts Serum - Normal Protein Antibody based methods 1986 Differential centrifugation Microparticles 229 2942561 Homo sapiens Platelet surface glycoproteins. Studies on resting and activated platelets and platelet membrane microparticles in normal subjects, and observations in patients during adult respiratory distress syndrome and cardiac surgery Plasma ts Plasma - Adult respiratory distress syndrome Protein Antibody based methods 1986 Differential centrifugation Microparticles 230 2294986 Homo sapiens Direct detection of activated platelets and platelet-derived microparticles in humans Plasma ts Plasma - Cardiopulmonary bypass Protein FACS 1990 FACS Microparticles 231 2294986 Homo sapiens Direct detection of activated platelets and platelet-derived microparticles in humans Plasma ts Plasma - Standardized bleeding time Protein FACS 1990 FACS Microparticles 232 7697722 Homo sapiens Secretory phospholipase A2 generates the novel lipid mediator lysophosphatidic acid in membrane microvesicles shed from activated cells Red blood cells ts Erythrocyte Lipids Thin layer chromatography|Cytofluorographic analysis 1995 Differential centrifugation Microvesicles 233 7697722 Homo sapiens Secretory phospholipase A2 generates the novel lipid mediator lysophosphatidic acid in membrane microvesicles shed from activated cells Inflammatory fluid ts Inflammatory fluids - Arthritis Lipids Thin layer chromatography|Cytofluorographic analysis 1995 Differential centrifugation Microvesicles 234 10648405 Homo sapiens Cellular origin and procoagulant properties of microparticles in meningococcal sepsis Plasma ts Plasma - Meningococcal sepsis - Survived Protein FACS 2000 Differential centrifugation|FACS Microparticles 235 10648405 Homo sapiens Cellular origin and procoagulant properties of microparticles in meningococcal sepsis Plasma ts Plasma - Normal Protein FACS 2000 Differential centrifugation|FACS Microparticles 236 10648405 Homo sapiens Cellular origin and procoagulant properties of microparticles in meningococcal sepsis Plasma ts Plasma - Meningococcal sepsis - Nonsurvived Protein FACS 2000 Differential centrifugation|FACS Microparticles 237 21293856 Homo sapiens Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC Melanoma cells cl Mel624.38 Protein Dot blot 2011 Differential centrifugation|Filtration|Ultrafiltration|Ultracentrifugation|Sucrose density gradient Exosomes 238 21293856 Homo sapiens Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC Ascites ts Malignant ascites - Ovarian cancer Protein Dot blot 2011 Differential centrifugation|Filtration|Ultrafiltration|Ultracentrifugation|Sucrose density gradient Exosomes 240 10233897 Homo sapiens Elevated levels of circulating procoagulant microparticles in patients with paroxysmal nocturnal hemoglobinuria and aplastic anemia Platelets ts Platelets - Paroxysmal nocturnal hemoglobinuria patients Protein|Lipids FACS 1999 Differential centrifugation|FACS Microparticles 241 16192427 Homo sapiens Circulating endothelial microparticles are associated with vascular dysfunction in patients with end-stage renal failure Plasma ts Plasma - End-stage renal failure patients Protein FACS 2005 Differential centrifugation|FACS Microparticles 242 9151784 Homo sapiens Transcellular activation of platelets and endothelial cells by bioactive lipids in platelet microparticles Platelets ts Platelets Lipids Mass spectrometry|High performance liquid chromatography 1997 Differential centrifugation Microparticles 243 22149170 Homo sapiens The Protein Interaction Network of Extracellular Vesicles Derived from Human Colorectal Cancer Cells Colorectal cancer cells cl HT29 Protein Mass spectrometry [LTQ]|Microarray|Western blotting|Confocal microscopy 2011 Differential centrifugation|Ultrafiltration|Ultracentrifugation|Density gradient centrifugation Extracellular vesicles 244 22148876 Homo sapiens Proteomic analysis of microvesicles derived from human mesenchymal stem cells Mesenchymal stem cells ts Mesenchymal stem cells - Rep 1 Protein Western blotting|Mass spectrometry[QTOF] 2011 Differential centrifugation|Ultrafiltration|Ultracentrifugation|Density gradient centrifugation Microvesicles 245 9126269 Homo sapiens Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations T cells cl H9 - non infected Protein|mRNA Radioimmunoassay 1997 Differential centrifugation|Sucrose density gradient Microvesicles 246 18425114 Homo sapiens Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells Glioblastoma cells cl U373vIII Protein Western blotting 2008 Differential centrifugation|Ultracentrifugation Microvesicles 247 15741221 Homo sapiens Tissue-factor-bearing microvesicles arise from lipid rafts and fuse with activated platelets to initiate coagulation Plasma ts Plasma - Normal Protein Western blotting 2005 Differential centrifugation|Immunobeads (TF) Microvesicles 248 15741221 Homo sapiens Tissue-factor-bearing microvesicles arise from lipid rafts and fuse with activated platelets to initiate coagulation Monocytic leukemia cells cl THP-1 Protein Western blotting 2005 Differential centrifugation Microvesicles 249 15741221 Homo sapiens Tissue-factor-bearing microvesicles arise from lipid rafts and fuse with activated platelets to initiate coagulation Monocytes ts Monocytes Protein Western blotting 2005 Differential centrifugation Microvesicles 250 9396452 Homo sapiens Cell-derived microparticles generated in patients during cardiopulmonary bypass are highly procoagulant Plasma ts Plasma - Systemic blood - Cardiopulmonary bypass patients Protein|Lipids FACS|Annexin V-FITC 1997 Differential centrifugation Microparticles 251 9396452 Homo sapiens Cell-derived microparticles generated in patients during cardiopulmonary bypass are highly procoagulant Plasma ts Plasma - Pericardial blood - Cardiopulmonary bypass patients Protein|Lipids FACS|Annexin V-FITC 1997 Differential centrifugation Microparticles 252 9126269 Homo sapiens Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations T cells cl H9 - HIV infected Protein Radioimmunoassay|Northern blotting 1997 Differential centrifugation|Sucrose density gradient Microvesicles 253 9126269 Homo sapiens Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations Leukemia cells cl CEM-SS - HIV non infected Protein Radioimmunoassay 1997 Differential centrifugation|Sucrose density gradient Microvesicles 254 9126269 Homo sapiens Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations Leukemia cells cl CEM-SS - HIV infected Protein Radioimmunoassay 1997 Differential centrifugation|Sucrose density gradient Microvesicles 255 9126269 Homo sapiens Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations Burkitt's lymphoma cl DAUDI - HIV non infected Protein Radioimmunoassay 1997 Differential centrifugation|Sucrose density gradient Microvesicles 256 9126269 Homo sapiens Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations Burkitt's lymphoma cl DAUDI - HIV infected Protein Radioimmunoassay 1997 Differential centrifugation|Sucrose density gradient Microvesicles 257 9126269 Homo sapiens Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations Leukemia cells cl MOLT-3 - HIV non infected Protein Radioimmunoassay 1997 Differential centrifugation|Sucrose density gradient Microvesicles 258 9126269 Homo sapiens Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations Leukemia cells cl MOLT-3 - HIV infected Protein Radioimmunoassay 1997 Differential centrifugation|Sucrose density gradient Microvesicles 259 18425114 Homo sapiens Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells Glioma cells cl U373 Protein Western blotting 2008 Differential centrifugation|Ultracentrifugation Microvesicles 260 10888925 Homo sapiens Transfer of the chemokine receptor CCR5 between cells by membrane-derived microparticles: a mechanism for cellular human immunodeficiency virus 1 infection Mononuclear cells ts Mononuclear cells Protein Western blotting 2000 Differential centrifugation|Filtration Microparticles 261 12805058 Homo sapiens Sickle blood contains tissue factor-positive microparticles derived from endothelial cells and monocytes Plasma ts Plasma - Sickle cell patients - Crisis Protein|Lipids FACS|Annexin V-FITC 2003 Differential centrifugation|Ultracentrifugation|FACS Microparticles 262 12805058 Homo sapiens Sickle blood contains tissue factor-positive microparticles derived from endothelial cells and monocytes Plasma ts Plasma - Sickle cell patients - Steady state Protein|Lipids FACS|Annexin V-FITC 2003 Differential centrifugation|Ultracentrifugation|FACS Microparticles 263 12805058 Homo sapiens Sickle blood contains tissue factor-positive microparticles derived from endothelial cells and monocytes Plasma ts Plasma - Normal Protein FACS 2003 Differential centrifugation|Ultracentrifugation|FACS Microparticles 264 18425114 Homo sapiens Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells Epidermoid cancer cells cl A431 Protein Western blotting 2008 Differential centrifugation|Ultracentrifugation Microvesicles 265 18425114 Homo sapiens Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells Endothelial cells cl HUVECs Protein Western blotting 2008 Differential centrifugation|Ultracentrifugation Microvesicles 266 18425114 Mus musculus Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells Plasma ts Plasma - Tumour Protein Western blotting 2008 Differential centrifugation|Ultracentrifugation Microvesicles 267 12757771 Homo sapiens Endothelial cells release phenotypically and quantitatively distinct microparticles in activation and apoptosis Endothelial cells cl Brain microvascular endothelial cells - ACBRI 376 - Control|TNF alpha|GFD Protein FACS 2003 Differential centrifugation|FACS Microparticles 268 12757771 Homo sapiens Endothelial cells release phenotypically and quantitatively distinct microparticles in activation and apoptosis Endothelial cells cl Glomerular microvascular endothelial cells - ACBRI 128 - Control|TNF alpha|GFD Protein FACS 2003 Differential centrifugation|FACS Microparticles 269 12757771 Homo sapiens Endothelial cells release phenotypically and quantitatively distinct microparticles in activation and apoptosis Endothelial cells cl Coronary artery endothelial cells - ACBRI 377 - Control|TNF alpha|GFD Protein FACS 2003 Differential centrifugation|FACS Microparticles 270 10903724 Homo sapiens Follicular dendritic cells carry MHC class II-expressing microvesicles at their surface Dendritic cells ts Follicular dendritic cells Protein Immunoelectron microscopy 2000 - Microvesicles 271 10903724 Homo sapiens Follicular dendritic cells carry MHC class II-expressing microvesicles at their surface B cells cl RN Protein Immunoelectron microscopy 2000 Differential centrifugation Exosomes 272 8896411 Homo sapiens High shear stress can initiate both platelet aggregation and shedding of procoagulant containing microparticles Platelets ts Platelets Protein|Lipids FACS|Annexin V-FITC 1996 Differential centrifugation|FACS Microparticles 273 12021310 Homo sapiens Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles T cells cl Jurkat Protein Western blotting 2002 Differential centrifugation|Ultracentrifugation Microvesicles 274 12021310 Homo sapiens Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles Melanoma cells cl Me15392 Protein Imunoelectron microscopy|Western blotting|FACS 2002 Differential centrifugation|Ultracentrifugation Microvesicles 275 12021310 Homo sapiens Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles Melanoma cells cl 501mel Protein Imunoelectron microscopy|Western blotting|FACS 2002 Differential centrifugation|Ultracentrifugation Microvesicles 276 12021310 Homo sapiens Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles Melanoma cells cl Me30966 Protein Imunoelectron microscopy|Western blotting|FACS 2002 Differential centrifugation|Ultracentrifugation Microvesicles 277 22030351 Homo sapiens Expression of PTRF in PC-3 cells modulates cholesterol dynamics and the actin cytoskeleton impacting secretion pathways Prostate cancer cells cl PC-3 Protein Mass spectrometry [QTOF] 2011 Differential centrifugation Exosomes 278 10233897 Homo sapiens Elevated levels of circulating procoagulant microparticles in patients with paroxysmal nocturnal hemoglobinuria and aplastic anemia Platelets ts Platelets - Normal Protein|Lipids FACS 1999 Differential centrifugation|FACS Microparticles 279 16192427 Homo sapiens Circulating endothelial microparticles are associated with vascular dysfunction in patients with end-stage renal failure Plasma ts Plasma - Normal Protein FACS 2005 Differential centrifugation|FACS Microparticles 280 15499615 Homo sapiens Microvesicles derived from activated platelets induce metastasis and angiogenesis in lung cancer Lung cancer cells cl A549 Protein|mRNA RT-PCR|FACS 2005 Differential centrifugation|FACS Microvesicles 281 15499615 Homo sapiens Microvesicles derived from activated platelets induce metastasis and angiogenesis in lung cancer Lung cancer cells cl A549 mRNA RT-PCR 2005 Differential centrifugation|Ultracentrifugation Exosomes 282 19234131 Homo sapiens Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR Lung cancer cells cl A549 Protein Western blotting 2009 Differential centrifugation Microvesicles 283 19234131 Homo sapiens Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR Colorectal cancer cells cl DLD-1 Protein Western blotting 2009 Differential centrifugation Microvesicles 284 12796750 Homo sapiens High levels of circulating endothelial microparticles in patients with acute coronary syndromes Plasma ts Plasma - Stable angina Protein FACS 2003 Differential centrifugation|FACS Microparticles 285 12796750 Homo sapiens High levels of circulating endothelial microparticles in patients with acute coronary syndromes Plasma ts Plasma - Unstable angina Protein FACS 2003 Differential centrifugation|FACS Microparticles 286 12417540 Homo sapiens Elevated numbers of tissue-factor exposing microparticles correlate with components of the metabolic syndrome in uncomplicated type 2 diabetes mellitus Plasma ts Plasma - Type 2 diabetes Protein FACS 2002 Differential centrifugation|FACS Microparticles 287 12417540 Homo sapiens Elevated numbers of tissue-factor exposing microparticles correlate with components of the metabolic syndrome in uncomplicated type 2 diabetes mellitus Plasma ts Plasma - Normal Protein FACS 2002 Differential centrifugation|FACS Microparticles 288 12196479 Homo sapiens Type 1 and type 2 diabetic patients display different patterns of cellular microparticles Plasma ts Plasma - Healthy donors Protein|Lipids FACS|Annexin V-FITC 2002 Differential centrifugation|FACS Microparticles 289 12196479 Homo sapiens Type 1 and type 2 diabetic patients display different patterns of cellular microparticles Plasma ts Plasma - Type 1 diabetes Protein|Lipids FACS|Annexin V-FITC 2002 Differential centrifugation|FACS Microparticles 290 12196479 Homo sapiens Type 1 and type 2 diabetic patients display different patterns of cellular microparticles Plasma ts Plasma - Type 2 diabetes Protein|Lipids FACS|Annexin V-FITC 2002 Differential centrifugation|FACS Microparticles 291 15072974 Rattus norvegicus Endothelium-derived microparticles impair endothelial function in vitro Endothelial cells cl RMVECs Protein Western blotting 2004 Differential centrifugation|Ultracentrifugation|FACS Microparticles 292 10415024 Homo sapiens Activated human T cells release bioactive Fas ligand and APO2 ligand in microvesicles T cells cl Jurkat - PHA stimulated Protein Western blotting|FACS 1999 Differential centrifugation|Ultracentrifugation|FACS Microvesicles 293 10415024 Homo sapiens Activated human T cells release bioactive Fas ligand and APO2 ligand in microvesicles T cells ts T cell blasts Protein Western blotting|FACS 1999 Differential centrifugation|Ultracentrifugation|FACS Microvesicles 294 2071604 Homo sapiens Evidence that agonist-induced activation of calpain causes the shedding of procoagulant-containing microvesicles from the membrane of aggregating platelets Platelets ts Platelets Protein Western blotting 1991 Differential centrifugation|Filtration Microvesicles 295 10233897 Homo sapiens Elevated levels of circulating procoagulant microparticles in patients with paroxysmal nocturnal hemoglobinuria and aplastic anemia Platelets ts Platelets - Aplastic anemia patients Lipids FACS 1999 Differential centrifugation|FACS Microparticles 296 12796750 Homo sapiens High levels of circulating endothelial microparticles in patients with acute coronary syndromes Plasma ts Plasma - Normal Protein FACS 2003 Differential centrifugation|FACS Microparticles 297 12796750 Homo sapiens High levels of circulating endothelial microparticles in patients with acute coronary syndromes Plasma ts Plasma - Acute coronary syndrome Protein FACS 2003 Differential centrifugation|FACS Microparticles 298 12796750 Homo sapiens High levels of circulating endothelial microparticles in patients with acute coronary syndromes Plasma ts Plasma - Coronary artery disease Protein FACS 2003 Differential centrifugation|FACS Microparticles 299 12796750 Homo sapiens High levels of circulating endothelial microparticles in patients with acute coronary syndromes Plasma ts Plasma - Myocardial infarction Protein FACS 2003 Differential centrifugation|FACS Microparticles 300 19234131 Homo sapiens Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR Epidermoid cancer cells cl A431 Protein Western blotting 2009 Differential centrifugation Microvesicles 301 19234131 Homo sapiens Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR Endothelial cells cl HUVECs Protein Western blotting 2009 Differential centrifugation Microvesicles 302 1321158 Rattus norvegicus Membrane anchoring of the autoantigen GAD65 to microvesicles in pancreatic beta-cells by palmitoylation in the NH2-terminal domain. Pancreatic cells cl Pancreatic cells Protein Immunoelectron microscopy 1992 Differential centrifugation Microvesicles 303 19930720 Homo sapiens Colorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells Colorectal cancer cells cl SW480 Protein|mRNA Western blotting|RT-PCR|Microarray [Illumina] 2009 Differential centrifugation|Ultrafiltration|OptiPrep density gradient Microvesicles 304 17478559 Mus musculus Identification and characterization of microvesicles secreted by 3T3-L1 adipocytes: redox- and hormone-dependent induction of milk fat globule-epidermal growth 8-associated microvesicles Adipocytes cl 3T3-L1 Protein Immunoelectron microscopy|Western blotting|Mass spectrometry [LCQ-DECA XP] 2007 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Microvesicles 305 17478559 Rattus norvegicus Identification and characterization of microvesicles secreted by 3T3-L1 adipocytes: redox- and hormone-dependent induction of milk fat globule-epidermal growth 8-associated microvesicles Adipocytes ts Adipocytes Protein Western blotting 2007 Differential centrifugation Microvesicles 306 16342139 Homo sapiens Proteomic analysis of malignant lymphocyte membrane microparticles using double ionization coverage optimization T cells cl CEM T cell - PHA activation Protein Mass spectrometry [MALDI TOF/TOF]|Mass spectrometry [QTOF] 2006 Differential centrifugation Microparticles 307 16342139 Homo sapiens Proteomic analysis of malignant lymphocyte membrane microparticles using double ionization coverage optimization T cells cl CEM T cell - ActD activation Protein Mass spectrometry [MALDI TOF/TOF]|Mass spectrometry [QTOF] 2006 Differential centrifugation Microparticles 308 16342139 Homo sapiens Proteomic analysis of malignant lymphocyte membrane microparticles using double ionization coverage optimization B cells ts B cells - Chronic B cell lymphoid patient Protein Mass spectrometry [MALDI TOF/TOF]|Mass spectrometry [QTOF] 2006 Differential centrifugation Microparticles 309 17536014 Homo sapiens Endothelial progenitor cell derived microvesicles activate an angiogenic program in endothelial cells by a horizontal transfer of Mrna Endothelial cells ts Endothelial cells - Healthy donors Protein|mRNA FACS|RT-PCR|Microarray [Illumina] 2007 Differential centrifugation|Ultracentrifugation|FACS Microvesicles 310 22148876 Homo sapiens Proteomic analysis of microvesicles derived from human mesenchymal stem cells Mesenchymal stem cells ts Mesenchymal stem cells - Rep 2 Protein Western blotting|Mass spectrometry[QTOF] 2011 Differential centrifugation|Ultrafiltration|Ultracentrifugation|Density gradient centrifugation Microvesicles 311 22148876 Homo sapiens Proteomic analysis of microvesicles derived from human mesenchymal stem cells Mesenchymal stem cells ts Mesenchymal stem cells - Rep 3 Protein Western blotting|Mass spectrometry[QTOF] 2011 Differential centrifugation|Ultrafiltration|Ultracentrifugation|Density gradient centrifugation Microvesicles 312 15499615 Homo sapiens Microvesicles derived from activated platelets induce metastasis and angiogenesis in lung cancer Lung cancer cells cl CRL 2062 Protein FACS 2005 Differential centrifugation|FACS Microvesicles 313 15499615 Homo sapiens Microvesicles derived from activated platelets induce metastasis and angiogenesis in lung cancer Lung cancer cells cl CRL 2066 Protein FACS 2005 Differential centrifugation|FACS Microvesicles 314 15499615 Homo sapiens Microvesicles derived from activated platelets induce metastasis and angiogenesis in lung cancer Lung cancer cells cl HTB 177 Protein FACS 2005 Differential centrifugation|FACS Microvesicles 315 15499615 Homo sapiens Microvesicles derived from activated platelets induce metastasis and angiogenesis in lung cancer Lung cancer cells cl HTB 183 Protein FACS 2005 Differential centrifugation|FACS Microvesicles 316 18472965 Homo sapiens Cathepsin B mediates the pH-dependent proinvasive activity of tumor-shed microvesicles Ovarian cancer cells cl CABA I Protein Westen blotting|Zymography 2008 Differential centrifugation Microvesicles 317 19266099 Homo sapiens Transfer of microRNAs by embryonic stem cell microvesicles Embryonic stem cells ts Embryonic stem cells mRNA|miRNA|snRNA RT-PCR 2009 Differential centrifugation Microvesicles 318 19483673 Homo sapiens Y-box protein-1 is actively secreted through a non-classical pathway and acts as an extracellular mitogen Monocytes ts Monocytes Protein Western blotting 2009 Differential centrifugation|Filtration Microvesicles 319 20615901 Homo sapiens Export of microRNAs and microRNA-protective protein by mammalian cells Lung cancer cells cl HepG2 miRNA RT-PCR 2010 Differential centrifugation Microvesicles 320 20615901 Homo sapiens Export of microRNAs and microRNA-protective protein by mammalian cells Epithelial cells cl A549 miRNA RT-PCR 2010 Differential centrifugation Microvesicles 321 19951903 Homo sapiens MicroRNA-29a regulates intestinal membrane permeability in patients with irritable bowel syndrome Plasma ts Plasma - Normal miRNA Microarray [ArrayExpress]|RT-PCR 2010 Differential centrifugation|Filtration Microvesicles 322 19951903 Homo sapiens MicroRNA-29a regulates intestinal membrane permeability in patients with irritable bowel syndrome Plasma ts Plasma - Iritable bowel syndrome patients miRNA Microarray [ArrayExpress]|RT-PCR 2010 Differential centrifugation|Filtration Microvesicles 323 20304794 Homo sapiens Functional delivery of viral miRNAs via exosomes B cells ts B cells - Transformed with Epstein–Barr virus Protein Western blotting 2010 Differential centrifugation Exosomes 324 20079801 Mus musculus Microvesicle entry into marrow cells mediates tissue-specific changes in mRNA by direct delivery of mRNA and induction of transcription Lung cells ts Lung cells Protein|miRNA FACS|RT-PCR 2010 Differential centrifugation|FACS Microvesicles 325 19289371 Homo sapiens Exosomal microRNA: a diagnostic marker for lung cancer Plasma ts Plasma - Lung adenocarcinoma patients miRNA Microarray 2009 Size exclusion chromatography|Immunobeads (EpCAM) Exosomes 326 20428099 Homo sapiens Nucleic acids within urinary exosomes/microvesicles are potential biomarkers for renal disease Urine ts Urine - Normal mRNA RT-PCR 2010 Differential centrifugation|Ultracentrifugation Microvesicles 327 20428099 Homo sapiens Nucleic acids within urinary exosomes/microvesicles are potential biomarkers for renal disease Urine ts Urine - Normal mRNA RT-PCR 2010 Differential centrifugation|Ultracentrifugation Exosomes 328 20428099 Rattus norvegicus Nucleic acids within urinary exosomes/microvesicles are potential biomarkers for renal disease Urine ts Urine - Renal acidosis mRNA RT-PCR 2010 Differential centrifugation|Ultracentrifugation Microvesicles 329 20304794 Homo sapiens Functional delivery of viral miRNAs via exosomes B cells cl B95-8 miRNA RT-PCR 2010 Differential centrifugation Exosomes 330 20304794 Homo sapiens Functional delivery of viral miRNAs via exosomes B cells cl X50-7 miRNA RT-PCR 2010 Differential centrifugation Exosomes 331 19627513 Homo sapiens Exosomes from human saliva as a source of microRNA biomarkers Saliva ts Saliva - Normal Protein|miRNA Western blotting|RT-PCR 2010 Differential centrifugation|Ultracentrifugation Exosomes 332 19627513 Homo sapiens Exosomes from human saliva as a source of microRNA biomarkers Saliva ts Saliva - Sjogren’s syndrome patients miRNA Microarray 2010 Differential centrifugation|Ultracentrifugation Exosomes 333 20976003 Homo sapiens Selective release of microRNA species from normal and malignant mammary epithelial cells Breast cancer cells cl MCF-7 Protein|miRNA Slot blot|RT-PCR|Microarray 2010 Differential centrifugation|Filtration Exosomes 334 20976003 Homo sapiens Selective release of microRNA species from normal and malignant mammary epithelial cells Breast cancer cells cl MDA-MB-231 Protein|miRNA Slot blot|RT-PCR 2010 Differential centrifugation|Filtration Exosomes 335 20976003 Homo sapiens Selective release of microRNA species from normal and malignant mammary epithelial cells Breast cancer cells cl BT-20 Protein|miRNA Slot blot|RT-PCR 2010 Differential centrifugation|Filtration Exosomes 336 20976003 Homo sapiens Selective release of microRNA species from normal and malignant mammary epithelial cells Breast cancer cells cl MCF 10A Protein|miRNA Slot blot|RT-PCR 2010 Differential centrifugation|Filtration Exosomes 337 20976003 Homo sapiens Selective release of microRNA species from normal and malignant mammary epithelial cells Breast cancer cells cl SK-BR-3 miRNA RT-PCR 2010 Differential centrifugation|Filtration Exosomes 338 20621060 Rattus norvegicus Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation Adipocytes cl 3T3-L1 mRNA|miRNA RT-PCR 2010 Differential centrifugation|Ultracentrifugation Microvesicles 339 20621060 Rattus norvegicus Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation Serum ts Serum mRNA RT-PCR 2010 Differential centrifugation|Ultracentrifugation Microvesicles 340 20615901 Homo sapiens Export of microRNAs and microRNA-protective protein by mammalian cells Lung cancer cells cl HepG2 miRNA RT-PCR 2010 Differential centrifugation Exosomes 341 20615901 Homo sapiens Export of microRNAs and microRNA-protective protein by mammalian cells Epithelial cells cl A549 miRNA RT-PCR 2010 Differential centrifugation Exosomes 342 22965126 Mus musculus Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells. Neuronal cells cl GT1-7 - Unifected Rep 1 miRNA RT-PCR|Western blotting 2012 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 343 22965126 Mus musculus Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells. Neuronal cells cl GT1-7 - Unifected Rep 2 miRNA RT-PCR 2012 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 344 22965126 Mus musculus Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells. Neuronal cells cl GT1-7 - Prion infected Rep 1 miRNA RT-PCR|Western blotting 2012 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 345 22965126 Mus musculus Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells. Neuronal cells cl GT1-7 - Prion infected Rep 2 miRNA RT-PCR 2012 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 346 22965126 Mus musculus Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells. Neuronal cells cl GT1-7 - Prion infected and uninfected Protein|miRNA RNA deep sequencing 2012 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 347 22285593 Homo sapiens Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes. Colorectal cancer cells cl LIM1863 - Ultracentrifugation Protein Mass spectrometry [Orbitrap]|Western blotting 2012 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 348 22285593 Homo sapiens Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes. Colorectal cancer cells cl LIM1863 - EpCAM immunoaffinity Protein Mass spectrometry [Orbitrap]|Western blotting 2012 Differential centrifugation|Filtration|Immunoaffinity (EpCAM)|Ultracentrifugation Exosomes 349 22285593 Homo sapiens Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes. Colorectal cancer cells cl LIM1863 - OptiPrep density gradient Protein Mass spectrometry [Orbitrap]|Western blotting 2012 Differential centrifugation|Filtration|Ultracentrifugation|Density gradient centrifugation Exosomes 353 24115447 Homo sapiens Comparative proteomics evaluation of plasma exosome isolation techniques and assessment of the stability of exosomes in normal human blood plasma Plasma ts Plasma - Normal Protein Mass spectrometry [Orbitrap Velos]|Western blotting 2013 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 354 24115447 Homo sapiens Comparative proteomics evaluation of plasma exosome isolation techniques and assessment of the stability of exosomes in normal human blood plasma Plasma ts Plasma - Normal Protein Mass spectrometry [Orbitrap Velos]|Western blotting 2013 Differential centrifugation|Filtration|Ultracentrifugation|Density gradient centrifugation Exosomes 355 24115447 Homo sapiens Comparative proteomics evaluation of plasma exosome isolation techniques and assessment of the stability of exosomes in normal human blood plasma Plasma ts Plasma - Normal Protein Mass spectrometry [Orbitrap Velos]|Western blotting 2013 Differential centrifugation|Filtration|Ultracentrifugation|Immunoaffinity (EpCAM) Exosomes 357 24352158 Homo sapiens Characterization and deep sequencing analysis of exosomal miRNA in human urine Urine ts Urine - Normal miRNA RNA deep sequencing 2014 Differential centrifugation|Norgen Biotek Exosome kit Exosomes 365 11878797 Homo sapiens Phospholipid composition of cell-derived microparticles determined by one-dimensional high-performance thin-layer chromatography. Plasma ts Normal-Plasma Lipids Thin layer chromatography 2002 - Microparticles 366 12414662 Homo sapiens Extracellular membrane vesicles from tumor cells promote angiogenesis via sphingomyelin. Endothelial cells cl HMEC-1 Lipids Thin layer chromatography 2002 - Membrane vesicles 367 12746840 Homo sapiens Proteomic analysis of human prostasomes. Seminal fluid ts Normal donors-Seminal fluid Protein Mass spectrometry 2003 - Prostasomes 368 16103114 Neisseria meningitidis Biochemical and functional characterization of membrane blebs purified from Neisseria meningitidis serogroup B. Neisseria meningitidis ts Normal-Neisseria meningitidis Serogroup B Protein Mass spectrometry 2005 - Membrane vesicles 369 16212402 Homo sapiens The platelet microparticle proteome. Platelets ts Normal donors-Platelets Protein Mass spectrometry 2005 - Microparticles 370 16456881 Neisseria meningitidis Outer membrane vesicles from group B Neisseria meningitidis delta gna33 mutant: proteomic and immunological comparison with detergent-derived outer membrane vesicles. Neisseria meningitidis ts Δgna33-Neisseria meningitidis MC58 Protein Mass spectrometry 2006 - Membrane vesicles 371 16456881 Neisseria meningitidis Outer membrane vesicles from group B Neisseria meningitidis delta gna33 mutant: proteomic and immunological comparison with detergent-derived outer membrane vesicles. Neisseria meningitidis ts Δgna33-Neisseria meningitidis NZ98/254 Protein Mass spectrometry 2006 - Membrane vesicles 372 17096383 Mus musculus Analysis of the extracellular matrix vesicle proteome in mineralizing osteoblasts. Osteoblasts cl MC3T3-E1 Protein Mass spectrometry 2007 - Matrix vesicles 373 17787032 Escherichia coli Global proteomic profiling of native outer membrane vesicles derived from Escherichia coli. Escherichia coli ts Normal-Escherichia coli DH5α Protein Mass spectrometry 2007 - Membrane vesicles 374 18039940 Cryptococcus neoformans Extracellular vesicles produced by Cryptococcus neoformans contain protein components associated with virulence. Cryptococcus neoformans ts Normal-Cryptococcus neoformans Protein Mass spectrometry 2008 - Exosomes/Extracellular vesicles 375 18095356 Gallus gallus Proteome analysis of matrix vesicles isolated from femurs of chicken embryo. 17-day-old embryo leg bone ts Normal-17-day-old embryo leg bone Protein Mass spectrometry 2008 - Matrix vesicles 376 18346024 Homo sapiens The proteome of red cell membranes and vesicles during storage in blood bank conditions. Red blood cells cl Microvesicle, Storage day 21-Red blood cells Protein Mass spectrometry 2008 - Microvesicles/Nanovesicles 377 18346024 Homo sapiens The proteome of red cell membranes and vesicles during storage in blood bank conditions. Red blood cells cl Microvesicle, Storage day 3-Red blood cells Protein Mass spectrometry 2008 - Microvesicles/Nanovesicles 378 18346024 Homo sapiens The proteome of red cell membranes and vesicles during storage in blood bank conditions. Red blood cells cl Microvesicle, Storage day 42-Red blood cells Protein Mass spectrometry 2008 - Microvesicles/Nanovesicles 379 18346024 Homo sapiens The proteome of red cell membranes and vesicles during storage in blood bank conditions. Red blood cells cl Nanovesicle, Storage day 21-Red blood cells Protein Mass spectrometry 2008 - Microvesicles/Nanovesicles 380 18346024 Homo sapiens The proteome of red cell membranes and vesicles during storage in blood bank conditions. Red blood cells cl Nanovesicle, Storage day 3-Red blood cells Protein Mass spectrometry 2008 - Microvesicles/Nanovesicles 381 18346024 Homo sapiens The proteome of red cell membranes and vesicles during storage in blood bank conditions. Red blood cells cl Nanovesicle, Storage day 42-Red blood cells Protein Mass spectrometry 2008 - Microvesicles/Nanovesicles 382 18373357 Homo sapiens Isolation and identification of potential urinary microparticle biomarkers of bladder cancer. Urine ts Normal donors-Urine Protein Mass spectrometry 2008 - Microparticles 383 18373357 Homo sapiens Isolation and identification of potential urinary microparticle biomarkers of bladder cancer. Urine ts Patients of bladder cancer-Urine Protein Mass spectrometry 2008 - Microparticles 384 18482993 Homo sapiens Protein composition of human epididymosomes collected during surgical vasectomy reversal: a proteomic and genomic approach. Epididymal fluid ts Normal-Epididymal fluid Protein Mass spectrometry 2008 - Prostasomes 385 18563738 Homo sapiens Comparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles. Endothelial cells cl Endothelial cells (HUVEC) Protein Mass spectrometry 2008 - Microparticles 386 18563738 Homo sapiens Comparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles. Endothelial cells cl Treated by PAI-1-Endothelial cell (HUVEC) Protein Mass spectrometry 2008 - Microparticles 387 18563738 Homo sapiens Comparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles. Endothelial cells cl Treated by TNF-alpha-Endothelial cells (HUVEC) Protein Mass spectrometry 2008 - Microparticles 388 18570454 Homo sapiens Proteomic analysis of exosomes from human neural stem cells by flow field-flow fractionation and nanoflow liquid chromatography-tandem mass spectrometry. Neural stem cells cl Neural stem cells (HB1.F3) Protein Mass spectrometry 2008 - Exosomes/Membrane vesicles 389 18819103 Homo sapiens Structural heterogeneity and protein composition of exosome-like vesicles (prostasomes) in human semen. Seminal fluid ts Normal donors-Seminal fluid Protein Mass spectrometry 2009 - Exosomes/Prostasomes 390 19158352 Homo sapiens Characterization of PKD protein-positive exosome-like vesicles. Urine ts Patients of autosomal recessive polycystic kidney disease-Urine Protein Mass spectrometry 2009 - Exosomes/Membrane particles 391 19327352 Bos taurus Anchorage-independent growth of breast carcinoma cells is mediated by serum exosomes. Serum ts Normal-Fetal bovine serum Protein Mass spectrometry 2009 - Exosomes 392 19351151 Mus musculus Characterization of vesicles secreted from insulinoma NIT-1 cells. Pancreatic cells cl Pancreatic beta cell (NIT-1) Protein Mass spectrometry 2009 - Exosomes 393 19369228 Homo sapiens Proteomic analysis reveals presence of platelet microparticles in endothelial progenitor cell cultures. Endothelial cells ts Normal-Endothelial progenitor cells Protein Mass spectrometry 2009 - Microparticles 394 19389847 Homo sapiens Mesenchymal stem cell-derived microvesicles protect against acute tubular injury. Mesenchymal stem cells ts Normal-Mesenchymal stem cells mRNA Microarray 2009 - Microvesicles 395 19413345 Homo sapiens Proteomic analysis of malignant B-cell derived microparticles reveals CD148 as a potentially useful antigenic biomarker for mantle cell lymphoma diagnosis. B cells ts Patients of chronic lymphocytic leukemia-B cells Protein Mass spectrometry 2009 - Microparticles 396 19413345 Homo sapiens Proteomic analysis of malignant B-cell derived microparticles reveals CD148 as a potentially useful antigenic biomarker for mantle cell lymphoma diagnosis. B cells ts Patients of mantle cell lymphoma-B cells Protein Mass spectrometry 2009 - Microparticles 397 19413345 Homo sapiens Proteomic analysis of malignant B-cell derived microparticles reveals CD148 as a potentially useful antigenic biomarker for mantle cell lymphoma diagnosis. B cells ts Patients of small cell lymphoma-B cells Protein Mass spectrometry 2009 - Microparticles 398 19530224 Homo sapiens Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes. Keratinocytes ts Differentiated-Keratinocytes Protein Mass spectrometry 2009 - Exosomes 399 19530224 Homo sapiens Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes. Keratinocytes ts Undifferentiated-Keratinocytes Protein Mass spectrometry 2009 - Exosomes 400 19548894 Acinetobacter baumannii Proteome analysis of outer membrane vesicles from a clinical Acinetobacter baumannii isolate. Acinetobacter baumannii ts Normal-Acinetobacter baumannii DU202 Protein Mass spectrometry 2009 - Membrane vesicles 401 19548909 Homo sapiens Differential stimulation of monocytic cells results in distinct populations of microparticles. Monocytes cl Monocytes (THP-1) Protein Mass spectrometry 2009 - Microparticles 402 19548909 Homo sapiens Differential stimulation of monocytic cells results in distinct populations of microparticles. Monocytes cl Stimulated by IgG-Monocytes (THP-1) Protein Mass spectrometry 2009 - Microparticles 403 19548909 Homo sapiens Differential stimulation of monocytic cells results in distinct populations of microparticles. Monocytes cl Stimulated by LPS-Monocytes (THP-1) Protein Mass spectrometry 2009 - Microparticles 404 19548909 Homo sapiens Differential stimulation of monocytic cells results in distinct populations of microparticles. Monocytes cl Stimulated by P-selectin-Ig-Monocytes (THP-1) Protein Mass spectrometry 2009 - Microparticles 405 19650833 Homo sapiens Human liver stem cell-derived microvesicles accelerate hepatic regeneration in hepatectomized rats. Hepatocytes ts Normal-Hepatocytes mRNA Microarray 2010 - Microvesicles 406 19806257 Homo sapiens Proteomic and functional characterisation of platelet microparticle size classes. Platelets ts Normal donors-Platelets Protein Mass spectrometry 2009 - Microparticles 407 19834908 Staphylococcus aureus Gram-positive bacteria produce membrane vesicles: proteomics-based characterization of Staphylococcus aureus-derived membrane vesicles. Staphylococcus aureus ts Normal-Staphylococcus aureus ATCC14458 Protein Mass spectrometry 2009 - Membrane vesicles 408 20031610 Homo sapiens Proteomics, metabolomics, and immunomics on microparticles derived from human atherosclerotic plaques. Carotid atherosclerotic plaques ts Normal-Carotid atherosclerotic plaque Metabolites Proton Nucelar Magnetic Resonance Spectrometry 2009 - Microparticles 409 20031610 Homo sapiens Proteomics, metabolomics, and immunomics on microparticles derived from human atherosclerotic plaques. Carotid atherosclerotic plaques ts Patients of carotid atherosclerosis-Carotid atherosclerotic plaque Protein Mass spectrometry 2009 - Microparticles 410 20052414 Homo sapiens Nanostructural and transcriptomic analyses of human saliva derived exosomes. Saliva ts Normal-Saliva mRNA Microarray 2010 - Exosomes/Membrane vesicles 411 20124223 Homo sapiens Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes. Squamous carcinoma cells cl Squamous carcinoma cell (A431) Protein Mass spectrometry 2010 - Exosomes 412 20156641 Homo sapiens Proteomics of microparticles after deep venous thrombosis. Plasma ts Normal donors and patients of deep venous thrombosis-Plasma Protein Mass spectrometry 2010 - Membrane vesicles/Microparticles 413 20535238 Rattus norvegicus Candidate biomarkers in exosome-like vesicles purified from rat and mouse urine samples. Urine ts Rats of liver injury-Urine Protein Mass spectrometry 2010 - Exosomes 414 20559436 Saccharomyces cerevisiae Characterization of yeast extracellular vesicles: evidence for the participation of different pathways of cellular traffic in vesicle biogenesis. Saccharomyces cerevisiae ts Normal-Saccharomyces cerevisiae Protein Mass spectrometry 2010 - Extracellular vesicles 415 20687614 Myxococcus xanthus Profiling the outer membrane proteome during growth and development of the social bacterium Myxococcus xanthus by selective biotinylation and analyses of outer membrane vesicles. Myxococcus xanthus ts Developmental cell-Myxococcus xanthus DK1622 Protein Mass spectrometry 2010 - Membrane vesicles 416 20687614 Myxococcus xanthus Profiling the outer membrane proteome during growth and development of the social bacterium Myxococcus xanthus by selective biotinylation and analyses of outer membrane vesicles. Myxococcus xanthus ts Vegetative cell-Myxococcus xanthus DK1622 Protein Mass spectrometry 2010 - Membrane vesicles 417 20956325 Bacillus anthracis Bacillus anthracis produces membrane-derived vesicles containing biologically active toxins. Bacillus anthracis ts Normal-Bacillus anthracis Sterne strain 34F2 Lipids Gas chromatography 2010 - Extracellular vesicles 418 21049385 Homo sapiens The plasma microparticle proteome. Plasma ts Normal donors-Plasma Protein Mass spectrometry 2010 - Microparticles 419 21136642 Mus musculus Oligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons? Oligodendrocytes ts Normal-Oligodendrocytes Protein Mass spectrometry 2007 - Exosomes 420 21136987 Helicobacter pylori Proteomic and functional characterization of the outer membrane vesicles from the gastric pathogen Helicobacter pylori. Helicobacter pylori ts Normal-Helicobacter pylori J99 Protein Mass spectrometry 2009 - Membrane vesicles 421 21136987 Helicobacter pylori Proteomic and functional characterization of the outer membrane vesicles from the gastric pathogen Helicobacter pylori. Helicobacter pylori ts Normal-Helicobacter pylori NCTC 11637 Protein Mass spectrometry 2009 - Membrane vesicles 422 21138299 Francisella philomiragia Proteomic characterization and functional analysis of outer membrane vesicles of Francisella novicida suggests possible role in virulence and use as a vaccine. Francisella philomiragia ts Normal-Francisella philomiragia ATCC25015 Protein Mass spectrometry 2011 - Membrane vesicles 423 21138299 Francisella tularensis Proteomic characterization and functional analysis of outer membrane vesicles of Francisella novicida suggests possible role in virulence and use as a vaccine. Francisella tularensis ts Normal-Francisella tularensis subsp. Novicida ATCC15482 Protein Mass spectrometry 2011 - Membrane vesicles 424 21179422 Mus musculus Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA. Mast cells cl Mast cells (MC/9) mRNA Microarray 2010 - Exosomes/Nanovesicles 425 21179422 Mus musculus Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA. Mast cells cl Oxidatively stressed-Mast cells (MC/9) mRNA Microarray 2010 - Exosomes/Nanovesicles 426 21386968 Acinetobacter baumannii Acinetobacter baumannii secretes cytotoxic outer membrane protein A via outer membrane vesicles. Acinetobacter baumannii ts Normal-Acinetobacter baumannii ATCC 19606T Protein Mass spectrometry 2011 - Membrane vesicles 427 21408115 Edwardsiella tarda Outer membrane vesicles as a candidate vaccine against edwardsiellosis. Edwardsiella tarda ts Normal-Edwardsiella tarda ED45 Protein Mass spectrometry 2011 - Membrane vesicles 428 21515422 Homo sapiens Proteomic characterization of biogenesis and functions of matrix vesicles released from mineralizing human osteoblast-like cells. Osteosarcoma cells cl Normal-Osteosarcoma cell (Saos-2 ATCC HTB-85) Protein Mass spectrometry 2011 - Matrix vesicles 429 21595033 Homo sapiens Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy. Urine ts Normal donors-Urine Protein Mass spectrometry 2011 - Exosomes 430 21595033 Homo sapiens Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy. Urine ts Patients of basement membrane nephropathy-Urine Protein Mass spectrometry 2011 - Exosomes 431 21595033 Homo sapiens Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy. Urine ts Patients of early IgA nephropathy-Urine Protein Mass spectrometry 2011 - Exosomes 432 21751344 Pseudomonas aeruginosa Proteomic analysis of outer membrane vesicles derived from Pseudomonas aeruginosa. Pseudomonas aeruginosa ts Normal-Pseudomonas aeruginosa PAO1 Protein Mass spectrometry 2011 - Exosomes/Membrane vesicles 433 22014850 Rattus norvegicus Proteomics of microparticles after experimental pulmonary embolism. Plasma ts Normal rat-Plasma Protein Mass spectrometry 2012 - Microparticles 434 22014850 Rattus norvegicus Proteomics of microparticles after experimental pulmonary embolism. Plasma ts Rat of pulmonary embolism model-Plasma Protein Mass spectrometry 2012 - Microparticles 435 22031862 Mus musculus Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes. Dendritic cells ts Bone marrow-derived immature dendritic cells miRNA Microarray 2012 - Exosomes/Nanovesicles 436 22031862 Mus musculus Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes. Dendritic cells ts Bone marrow-derived mature dendritic cells miRNA Microarray 2012 - Exosomes/Nanovesicles 437 22106071 Homo sapiens Proteomic analysis of urine exosomes by multidimensional protein identification technology (MudPIT). Urine ts Normal donors-Urine Protein Mass spectrometry 2012 - Exosomes/Membrane vesicles 438 22114730 Staphylococcus aureus Staphylococcus aureus produces membrane-derived vesicles that induce host cell death. Staphylococcus aureus ts Normal-Staphylococcus aureus 06ST1048 Protein Mass spectrometry 2011 - Membrane vesicles/Nanovesicles 439 22129587 Bos taurus Bovine milk exosome proteome. Bovine milk ts Normal cow-Milk Protein Mass spectrometry 2012 - Exosomes/Membrane vesicles 440 22251860 Homo sapiens RNA expression patterns in serum microvesicles from patients with glioblastoma multiforme and controls. Serum ts Normal-Serum mRNA Microarray 2012 - Exosomes/Microvesicles 441 22251860 Homo sapiens RNA expression patterns in serum microvesicles from patients with glioblastoma multiforme and controls. Serum ts Patients of glioblastoma -Serum mRNA Microarray 2012 - Exosomes/Microvesicles 442 22288420 Paracoccidioides brasiliensis Vesicle and vesicle-free extracellular proteome of Paracoccidioides brasiliensis: comparative analysis with other pathogenic fungi. Paracoccidioides brasiliensis ts Normal-Paracoccidioides brasiliensis Pb18 Protein Mass spectrometry 2012 - Extracellular vesicles 443 22329422 Homo sapiens Quantitative proteome profiling of normal human circulating microparticles. Plasma ts Normal-Platelet-poor plasma Protein Mass spectrometry 2012 - Microparticles 444 22418980 Homo sapiens A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes. Urine ts Normal_high density-Urine Protein Mass spectrometry 2012 - Exosomes 445 22418980 Homo sapiens A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes. Urine ts Normal_low density-Urine Protein Mass spectrometry 2012 - Exosomes 446 22428779 Klebsiella pneumoniae Klebsiella pneumoniae secretes outer membrane vesicles that induce the innate immune response. Klebsiella pneumoniae ts Normal-Klebsiella pneumoniae ATCC 13883 Protein Mass spectrometry 2012 - Membrane vesicles 447 22444574 Homo sapiens Proteomic analysis of microvesicles in human saliva by gel electrophoresis with liquid chromatography-mass spectrometry. Saliva ts Normal donors-Saliva Protein Mass spectrometry 2012 - Exosomes/Microvesicles 448 22448133 Pseudomonas aeruginosa Vesiculation from Pseudomonas aeruginosa under SOS. Pseudomonas aeruginosa ts Normal-Pseudomonas aeruginosa PAO1 Protein Mass spectrometry 2012 - Membrane vesicles 449 22448133 Pseudomonas aeruginosa Vesiculation from Pseudomonas aeruginosa under SOS. Pseudomonas aeruginosa ts ΔlexAN-Pseudomonas aeruginosa PAO1 Protein Mass spectrometry 2012 - Membrane vesicles 450 22451062 Homo sapiens A hyphenated microLC-Q-TOF-MS platform for exosomal lipidomics investigations: application to RCC urinary exosomes. Urine ts Normal-Urine Lipids Mass spectrometry 2012 - Exosomes 451 22451062 Homo sapiens A hyphenated microLC-Q-TOF-MS platform for exosomal lipidomics investigations: application to RCC urinary exosomes. Urine ts Patients of renal cell carcinoma-Urine Lipids Mass spectrometry 2012 - Exosomes 452 22506041 Mus musculus Cardiomyocyte microvesicles contain DNA/RNA and convey biological messages to target cells. Cardiomyocytes cl Cardiomyocyte cells (HL-1) mRNA Microarray 2012 - Exosomes/Membrane vesicles/Microvesicles/Prostasomes 453 22635005 Homo sapiens Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. Melanoma cells cl B16-F10, SK-MEL-202, SK-MEL035, SK-MEL-265 Protein Mass spectrometry 2012 - Exosomes 454 22669077 Homo sapiens The proteome of erythrocyte-derived microparticles from plasma: new clues for erythrocyte aging and vesiculation. Plasma ts Normal-Blood Protein Mass spectrometry 2012 - Microparticles 455 22682234 Homo sapiens Microparticle conferred microRNA profiles - implications in the transfer and dominance of cancer traits. Leukemia cells cl Drug-resistant acute lymphoblastic leukemia cell (CCRF-CEM MDR variant VLB100) miRNA Microarray 2012 - Membrane vesicles/Microparticles 456 22682234 Homo sapiens Microparticle conferred microRNA profiles - implications in the transfer and dominance of cancer traits. Breast cancer cells cl Normal-Drug-resistant breast adenocarcinoma cells (MCF-7 MDR variant MCF-7/DX) miRNA Microarray 2012 - Membrane vesicles/Microparticles 457 22723089 Homo sapiens Exosomes as Biomarker Enriched Microvesicles: Characterization of Exosomal Proteins derived from a Panel of Prostate Cell Lines with distinct AR phenotypes. Prostate cancer cells cl PC3, DU145, VcaP, LNCaP, C4-2, RWPE-1 Lipids Mass spectrometry 2012 - Exosomes/Membrane vesicles/Microvesicles 458 22740476 Homo sapiens Restoration of full-length APC protein in SW480 colon cancer cells induces exosome-mediated secretion of DKK-4. Colorectal cancer cells cl SW480 Protein Mass spectrometry 2012 - Exosomes 459 22745761 Paracoccidioides brasiliensis Lipidomic Analysis of Extracellular Vesicles from the Pathogenic Phase of Paracoccidioides brasiliensis. Paracoccidioides brasiliensis ts Normal-Paracoccidioides brasiliensis Pb18 Lipids Mass spectrometry 2012 - Extracellular vesicles 460 22745761 Paracoccidioides brasiliensis Lipidomic Analysis of Extracellular Vesicles from the Pathogenic Phase of Paracoccidioides brasiliensis. Paracoccidioides brasiliensis ts Normal-Paracoccidioides brasiliensis Pb3 Lipids Mass spectrometry 2012 - Extracellular vesicles 461 22848702 Homo sapiens Medulloblastoma exosome proteomics yield functional roles for extracellular vesicles. Medulloblastoma cells cl Medulloblastoma cells (D283MED) Protein Mass spectrometry 2012 - Exosomes/Membrane vesicles/Extracellular vesicles 462 22849433 Homo sapiens Selective extracellular vesicle-mediated export of an overlapping set of microRNAs from multiple cell types. Embryonic kidney cells cl miR-146a-treated-Embryonic kidney cells (HEK293T) miRNA Next generation sequencing 2012 - Extracellular vesicles 463 22849433 Homo sapiens Selective extracellular vesicle-mediated export of an overlapping set of microRNAs from multiple cell types. Embryonic kidney cells cl Embryonic kidney cells (HEK293T) miRNA Next generation sequencing 2012 - Extracellular vesicles 464 22909304 Pseudomonas aeruginosa Identification of proteins associated with the Pseudomonas aeruginosa biofilm extracellular matrix. Pseudomonas aeruginosa ts Normal_biofilm-Pseudomonas aeruginosa PAO1 Protein Mass spectrometry 2012 - Membrane vesicles 465 22909304 Pseudomonas aeruginosa Identification of proteins associated with the Pseudomonas aeruginosa biofilm extracellular matrix. Pseudomonas aeruginosa ts Normal_planktonic culture-Pseudomonas aeruginosa PAO1 Protein Mass spectrometry 2012 - Membrane vesicles 466 22966805 Acinetobacter baumannii Extracellular proteome of a highly invasive multidrug-resistant clinical strain of Acinetobacter baumannii. Acinetobacter baumannii ts Normal-Acinetobacter baumannii AbH12O-A2 Protein Mass spectrometry 2012 - Membrane vesicles 467 23000592 Homo sapiens In-depth analysis of the secretome identifies three major independent secretory pathways in differentiating human myoblasts. Neonatal myoblast cells ts Patient of developmental heart defect_exosome-Neonatal myoblast cells Protein Mass spectrometry 2012 - Microvesicles/Nanovesicles 468 23000592 Homo sapiens In-depth analysis of the secretome identifies three major independent secretory pathways in differentiating human myoblasts. Neonatal myoblast cells ts Patient of developmental heart defect_microparticle-Neonatal myoblast cells Protein Mass spectrometry 2012 - Microvesicles/Nanovesicles 469 23029346 Echinostoma caproni Extracellular Vesicles from Parasitic Helminths Contain Specific Excretory/Secretory Proteins and Are Internalized in Intestinal Host Cells. Echinostoma caproni ts Normal-Echinostoma caproni from ICR mice Protein Mass spectrometry 2012 - Exosomes/Extracellular vesicles/Microvesicles 470 23029346 Fasciola hepatica Extracellular Vesicles from Parasitic Helminths Contain Specific Excretory/Secretory Proteins and Are Internalized in Intestinal Host Cells. Fasciola hepatica ts Normal-Fasciola hepatica from cow liver Protein Mass spectrometry 2012 - Exosomes/Extracellular vesicles/Microvesicles 471 23035643 Drosophila melanogaster Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes. Drosophila S2 cells ts Normal-Drosophila S2 tub-Wg Protein Mass spectrometry 2012 - Exosomes 472 23043909 Pseudomonas syringae Virulence factors are released in association with outer membrane vesicles of Pseudomonas syringae pv. tomato T1 during normal growth. Pseudomonas syringae ts Normal-Pseudomonas syringae pv tomato T1 Protein Mass spectrometry 2012 - Membrane vesicles 473 23056467 Homo sapiens Cause or Effect of Arteriogenesis: Compositional Alterations of Microparticles from CAD Patients Undergoing External Counterpulsation Therapy. Plasma ts Patients of external counterpulsation therapy-Blood Protein Mass spectrometry 2012 - Microparticles 474 23056502 Homo sapiens Identifying mRNA, MicroRNA and Protein Profiles of Melanoma Exosomes. Melanoma cells cl Epidermal melanocytes (HEMa-LP) miRNA Microarray 2012 - Exosomes 475 23056502 Homo sapiens Identifying mRNA, MicroRNA and Protein Profiles of Melanoma Exosomes. Melanoma cells cl Epidermal melanocytes (HEMa-LP) mRNA Microarray 2012 - Exosomes 476 23056502 Homo sapiens Identifying mRNA, MicroRNA and Protein Profiles of Melanoma Exosomes. Melanoma cells cl A375 miRNA Microarray 2012 - Exosomes 477 23056502 Homo sapiens Identifying mRNA, MicroRNA and Protein Profiles of Melanoma Exosomes. Melanoma cells cl A375 mRNA Microarray 2012 - Exosomes 478 23082778 Homo sapiens Comparative and Targeted Proteomic Analyses of Urinary Microparticles from Bladder Cancer and Hernia Patients. Urine ts Patients of bladder cancer-Urine Protein Mass spectrometry 2012 - Exosomes/Membrane vesicles 479 23082778 Homo sapiens Comparative and Targeted Proteomic Analyses of Urinary Microparticles from Bladder Cancer and Hernia Patients. Urine ts Patients of hernia-Urine Protein Mass spectrometry 2012 - Exosomes/Membrane vesicles 480 23161513 Homo sapiens Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS. Colorectal cancer cells cl DKO-1 Protein Mass spectrometry 2012 - Exosomes 481 23161513 Homo sapiens Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS. Colorectal cancer cells cl Dks-8 Protein Mass spectrometry 2012 - Exosomes 482 23161513 Homo sapiens Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS. Colorectal cancer cells cl DLD-1 Protein Mass spectrometry 2012 - Exosomes 483 23214914 Trypanosoma cruzi Proteomic analysis of Trypanosoma cruzi secretome: characterization of two populations of extracellular vesicles and soluble proteins. Epimastigotes ts Normal_larger vesicles-Epimastigotes Protein Mass spectrometry 2012 - Exosomes/Extracellular vesicles/Ectosomes 484 23214914 Trypanosoma cruzi Proteomic analysis of Trypanosoma cruzi secretome: characterization of two populations of extracellular vesicles and soluble proteins. Epimastigotes ts Normal_smaller vesicles-Epimastigotes Protein Mass spectrometry 2012 - Exosomes/Extracellular vesicles/Ectosomes 485 23214914 Trypanosoma cruzi Proteomic analysis of Trypanosoma cruzi secretome: characterization of two populations of extracellular vesicles and soluble proteins. Metacyclic trypomastigotes ts Normal_larger vesicles-Metacyclic trypomastigotes Protein Mass spectrometry 2012 - Exosomes/Extracellular vesicles/Ectosomes 486 23230278 Homo sapiens Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids. Colorectal cancer cells cl A33 affinity purified exosomes-Colorectal cancer cells (LIM1863) Protein Mass spectrometry 2012 - Exosomes/Extracellular vesicles/Microvesicles 487 23230278 Homo sapiens Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids. Colorectal cancer cells cl EpCAM affinity purified exosomes-Colorectal cancer cells (LIM1863) Protein Mass spectrometry 2012 - Exosomes/Extracellular vesicles/Microvesicles 488 23230278 Homo sapiens Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids. Colorectal cancer cells cl Shed vesicles-Colorectal cancer cells (LIM1863) Protein Mass spectrometry 2012 - Exosomes/Extracellular vesicles/Microvesicles 489 23260141 Mus musculus Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration. Fibroblasts ts Normal-Fibroblasts (L cells) Protein Mass spectrometry 2012 - Exosomes 490 23264574 Francisella novicida Production of Outer Membrane Vesicles and Outer Membrane Tubes by Francisella novicida. Francisella novicida ts Normal_early stationary phase-Francisella novicida ATCC 15482 Protein Mass spectrometry 2012 - Membrane vesicles 491 23264574 Francisella novicida Production of Outer Membrane Vesicles and Outer Membrane Tubes by Francisella novicida. Francisella novicida ts Normal_exponential phase-Francisella novicida ATCC 15482 Protein Mass spectrometry 2012 - Membrane vesicles 492 23333927 Homo sapiens Characterization and proteomic analysis of ovarian cancer-derived exosomes. Ovarian cancer cells cl IGROV1 Protein Mass spectrometry 2013 - Exosomes 493 23333927 Homo sapiens Characterization and proteomic analysis of ovarian cancer-derived exosomes. Ovarian cancer cells cl OVCAR-3 Protein Mass spectrometry 2013 - Exosomes 494 23344721 Homo sapiens miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles. Glioblastoma cells cl Primary glioblastoma multiforme cells (11/5) mRNA Microarray 2012 - Microvesicles 495 23344721 Homo sapiens miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles. Glioblastoma cells cl Primary glioblastoma multiforme cells (20/3) mRNA Microarray 2012 - Microvesicles 496 23344721 Homo sapiens miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles. Melanoma cells cl Primary malignant melanoma cells (0105) mRNA Microarray 2012 - Microvesicles 497 23344721 Homo sapiens miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles. Melanoma cells cl Primary malignant melanoma cells (0664) mRNA Microarray 2012 - Microvesicles 498 23376485 Homo sapiens Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. Urine ts Normal-Urine Protein Mass spectrometry 2013 - Exosomes/Membrane vesicles 499 23404715 Homo sapiens Distinct lipid compositions of two types of human prostasomes. Seminal fluid ts 100 nm-Seminal fluid Lipids Liquid chromatography 2013 - Prostasomes 500 23404715 Homo sapiens Distinct lipid compositions of two types of human prostasomes. Seminal fluid ts 50 nm-Seminal fluid Lipids Liquid chromatography 2013 - Prostasomes 501 23410224 Neisseria meningitidis Quantitative proteomics reveals distinct differences in the protein content of outer membrane vesicle vaccines. Neisseria meningitidis ts Normal-Neisseria meningitidis H44/76 (serogroup B) Protein Mass spectrometry 2013 - Membrane vesicles 502 23436686 Homo sapiens A comprehensive characterization of membrane vesicles released by autophagic human endothelial cells. Endothelial cells ts Serum-starved-Human umbilical vascular endothelial cells Protein Mass spectrometry 2013 - Membrane vesicles/Extracellular vesicles 503 23459212 Bos taurus Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis. Bovine milk ts Staphylococcus aureus-infected-Milk Protein Mass spectrometry 2013 - Exosomes 504 23465879 Homo sapiens Lipidomic analysis of human placental Syncytiotrophoblast microvesicles in adverse pregnancy outcomes. Placenta ts Normal-Placental basal plate/decidua Lipids Mass spectrometry 2013 - Microvesicles 505 23465879 Homo sapiens Lipidomic analysis of human placental Syncytiotrophoblast microvesicles in adverse pregnancy outcomes. Placenta ts Preeclampsia-Placental basal plate/decidua Lipids Mass spectrometry 2013 - Microvesicles 506 23465879 Homo sapiens Lipidomic analysis of human placental Syncytiotrophoblast microvesicles in adverse pregnancy outcomes. Placenta ts Recurrent miscarriage-Placental basal plate/decidua Lipids Mass spectrometry 2013 - Microvesicles 507 23511837 Homo sapiens Differential protein profiling of renal cell carcinoma urinary exosomes. Urine ts Normal-Urine Protein Mass spectrometry 2013 - Exosomes/Nanovesicles 508 23511837 Homo sapiens Differential protein profiling of renal cell carcinoma urinary exosomes. Urine ts Renal cell carcinoma patient-Urine Protein Mass spectrometry 2013 - Exosomes/Nanovesicles 509 23521563 Homo sapiens First identification of Ewing's sarcoma-derived extracellular vesicles and exploration of their biological and potential diagnostic implications. Ewing's sarcoma cells cl A673 mRNA Microarray 2013 - Exosomes/Extracellular vesicles 510 23521563 Homo sapiens First identification of Ewing's sarcoma-derived extracellular vesicles and exploration of their biological and potential diagnostic implications. Ewing's sarcoma cells cl SB-KMS-KS1 mRNA Microarray 2013 - Exosomes/Extracellular vesicles 511 23521563 Homo sapiens First identification of Ewing's sarcoma-derived extracellular vesicles and exploration of their biological and potential diagnostic implications. Ewing's sarcoma cells cl SK-N-MC mRNA Microarray 2013 - Exosomes/Extracellular vesicles 512 23533145 Homo sapiens In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Urine ts Low-grade prostate cancer patient-Expressed prostatic secretions in urine Protein Mass spectrometry 2013 - Exosomes/Microvesicles 513 23533145 Homo sapiens In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Urine ts Normal-Expressed prostatic secretions in urine Protein Mass spectrometry 2013 - Exosomes/Microvesicles 514 23539611 Homo sapiens microRNA signature is altered in both human epididymis and seminal microvesicles following vasectomy. Seminal fluid ts Normal-Seminal plasma miRNA Microarray 2013 - Microvesicles 515 23539611 Homo sapiens microRNA signature is altered in both human epididymis and seminal microvesicles following vasectomy. Seminal fluid ts Vasectomy-Seminal plasma miRNA Microarray 2013 - Microvesicles 516 23539611 Homo sapiens microRNA signature is altered in both human epididymis and seminal microvesicles following vasectomy. Seminal fluid ts Vasovasostomy-Seminal plasma miRNA Microarray 2013 - Microvesicles 517 23585443 Homo sapiens Proteome profiling of exosomes derived from human primary and metastatic colorectal cells reveal differential expression of key metastatic factors and signal transduction components. Colorectal cancer cells cl SW480 Protein Mass spectrometry 2013 - Exosomes/Membrane vesicles 518 23585443 Homo sapiens Proteome profiling of exosomes derived from human primary and metastatic colorectal cells reveal differential expression of key metastatic factors and signal transduction components. Colorectal cancer cells cl SW620 Protein Mass spectrometry 2013 - Exosomes/Membrane vesicles 519 23585444 Homo sapiens Identification and characterization of proteins isolated from microvesicles derived from human lung cancer pleural effusions. Malignant pleural effusions ts Non-small cell lung cancer patient-Lung cancer pleural effusion Protein Mass spectrometry 2013 - Exosomes/Microvesicles/Ectosomes/Microparticles 520 23601281 Homo sapiens Proteomic characterization of human platelet-derived microparticles. Platelets ts Platelets purifird from blood Protein Mass spectrometry 2013 - Microparticles 521 23645497 Canis lupus familiaris Oncogenic H-Ras reprograms Madin-Darby canine kidney (MDCK) cell-derived exosomal proteins following epithelial-mesenchymal transition. Kidney cells cl Normal-Madin-Darby canine kidney cell (MDCK) Protein Mass spectrometry 2013 - Exosomes/Extracellular vesicles 522 23645497 Canis lupus familiaris Oncogenic H-Ras reprograms Madin-Darby canine kidney (MDCK) cell-derived exosomal proteins following epithelial-mesenchymal transition. Kidney cells cl Ras-transformed MDCK cells (21D1) Protein Mass spectrometry 2013 - Exosomes/Extracellular vesicles 523 23658846 Mus musculus Immunomodulatory impact of leishmania-induced macrophage exosomes: a comparative proteomic and functional analysis. Macrophage cl Leishmania-infected-Macrophage (J774A.1) Protein Mass spectrometry 2013 - Exosomes 524 23658846 Mus musculus Immunomodulatory impact of leishmania-induced macrophage exosomes: a comparative proteomic and functional analysis. Macrophage cl LPS-treated-Macrophage (J774A.1) Protein Mass spectrometry 2013 - Exosomes 525 23658846 Mus musculus Immunomodulatory impact of leishmania-induced macrophage exosomes: a comparative proteomic and functional analysis. Macrophage cl Normal-Macrophage (J774A.1) Protein Mass spectrometry 2013 - Exosomes 526 23660474 Homo sapiens Heterogeneity in neutrophil microparticles reveals distinct proteome and functional properties. Neutrophils ts Stimulated in fluid phase-Neutrophil Protein Mass spectrometry 2013 - Microparticles 527 23660474 Homo sapiens Heterogeneity in neutrophil microparticles reveals distinct proteome and functional properties. Neutrophils ts Stimulated in immobile phase-Neutrophil Protein Mass spectrometry 2013 - Microparticles 528 23767874 Homo sapiens Biochemical and biological characterization of exosomes containing prominin-1/CD133. Melanoma cells cl Malignant melanoma (FEMX-I) Lipids Mass spectrometry 2013 - Exosomes/Microvesicles 529 23786572 Homo sapiens Phospholipidomics of Human Blood Microparticles. Plasma ts Normal-Blood Lipids Mass spectrometry 2013 - Microparticles 530 23803555 Bos taurus Epididymosomes Convey Different Repertoires of MicroRNAs Throughout the Bovine Epididymis. Epithelial cells ts Normal-Caput epithelial cells miRNA Microarray 2013 - Membrane vesicles 531 23803555 Bos taurus Epididymosomes Convey Different Repertoires of MicroRNAs Throughout the Bovine Epididymis. Caput luminal fluid ts Normal-Caput luminal fluid miRNA Microarray 2013 - Membrane vesicles 532 23803555 Bos taurus Epididymosomes Convey Different Repertoires of MicroRNAs Throughout the Bovine Epididymis. Epithelial cells ts Normal-Cauda epithelial cells miRNA Microarray 2013 - Membrane vesicles 533 23803555 Bos taurus Epididymosomes Convey Different Repertoires of MicroRNAs Throughout the Bovine Epididymis. Cauda luminal fluid ts Normal-Cauda luminal fluid miRNA Microarray 2013 - Membrane vesicles 534 23818640 Homo sapiens Modulation of B-cell exosome proteins by gamma herpesvirus infection. B cells cl EBV- and KSHV-infected B cells (JSC-1, BC1) Protein Mass spectrometry 2013 - Exosomes/Microvesicles/Oncosomes/Microparticles 535 23818640 Homo sapiens Modulation of B-cell exosome proteins by gamma herpesvirus infection. B cells cl EBV-infected B cells (#1, HLJ, IM9, CP) Protein Mass spectrometry 2013 - Exosomes/Microvesicles/Oncosomes/Microparticles 536 23818640 Homo sapiens Modulation of B-cell exosome proteins by gamma herpesvirus infection. B cells cl KSHV-infected B cell (JC, BC3, BCP1, BCBL1) Protein Mass spectrometry 2013 - Exosomes/Microvesicles/Oncosomes/Microparticles 537 23818640 Homo sapiens Modulation of B-cell exosome proteins by gamma herpesvirus infection. B cells ts Normal B cells (BJAB) Protein Mass spectrometry 2013 - Exosomes/Microvesicles/Oncosomes/Microparticles 538 23844026 Homo sapiens Characterization of human thymic exosomes. Thymus ts Normal-Thymus Protein Mass spectrometry 2013 - Exosomes 539 23853596 Trichomonas vaginalis Trichomonas vaginalis Exosomes Deliver Cargo to Host Cells and Mediate Host∶Parasite Interactions. Trichomonas vaginalis ts Normal-Trichomonas vaginalis B7RC2 Protein Mass spectrometry 2013 - Exosomes/Microvesicles 540 23886663 Homo sapiens LRRK2 Secretion in Exosomes is Regulated by 14-3-3. Urine ts Normal-Urine Protein Mass spectrometry 2013 - Exosomes/Microvesicles 541 23935504 Homo sapiens A Novel Role for Pro-Coagulant Microvesicles in the Early Host Defense against Streptococcus pyogenes. Peripheral blood mononucelar cells ts Normal-Peripheral blood mononucelar cells Protein Mass spectrometry 2013 - Microvesicles 542 23935504 Homo sapiens A Novel Role for Pro-Coagulant Microvesicles in the Early Host Defense against Streptococcus pyogenes. Peripheral blood mononucelar cells ts Procoagulant (M1 protein-treated)-Peripheral blood mononucelar cells Protein Mass spectrometry 2013 - Microvesicles 543 23977379 Listeria monocytogenes Transcription Factor σ(B) Plays an Important Role in the Production of Extracellular Membrane-Derived Vesicles in Listeria monocytogenes. Listeria monocytogenes ts Normal-Listeria monocytogenes 10403S (wild-type) Protein Mass spectrometry 2013 - Membrane vesicles 544 23977379 Listeria monocytogenes Transcription Factor σ(B) Plays an Important Role in the Production of Extracellular Membrane-Derived Vesicles in Listeria monocytogenes. Listeria monocytogenes ts Normal-Listeria monocytogenes 10403S (ΔsigB mutant) Protein Mass spectrometry 2013 - Membrane vesicles 545 23983189 Homo sapiens Characterization of Multiple Myeloma Vesicles by Label-Free Relative Quantitation. B cells cl MM.1S Protein Mass spectrometry 2013 - Exosomes/Extracellular vesicles/Microvesicles 546 23983189 Homo sapiens Characterization of Multiple Myeloma Vesicles by Label-Free Relative Quantitation. B cells cl U266 Protein Mass spectrometry 2013 - Exosomes/Extracellular vesicles/Microvesicles 547 24009880 Homo sapiens Characterization of mRNA and microRNA in human mast cell-derived exosomes and their transfer to other mast cells and blood CD34 progenitor cells. Mast cells cl HMC-1 miRNA Microarray 2012 - Exosomes/Extracellular vesicles 548 24009880 Homo sapiens Characterization of mRNA and microRNA in human mast cell-derived exosomes and their transfer to other mast cells and blood CD34 progenitor cells. Mast cells cl HMC1 mRNA Microarray 2012 - Exosomes/Extracellular vesicles 549 24009881 Homo sapiens Quantitative proteomics of extracellular vesicles derived from human primary and metastatic colorectal cancer cells. Colorectal cancer cells cl SW480 Protein Mass spectrometry 2012 - Exosomes/Extracellular vesicles/Microvesicles/Ectosomes 550 24009881 Homo sapiens Quantitative proteomics of extracellular vesicles derived from human primary and metastatic colorectal cancer cells. Colorectal cancer cells cl SW620 Protein Mass spectrometry 2012 - Exosomes/Extracellular vesicles/Microvesicles/Ectosomes 551 24009886 Homo sapiens Cellular stress conditions are reflected in the protein and RNA content of endothelial cell-derived exosomes. Endothelial cells cl Stressed (hypoxia, TNF-alpha-induced activation, high glucose and mannose concentrations)-Endothelial cells (HMEC-1) Protein Mass spectrometry 2012 - Exosomes/Extracellular vesicles 552 24009898 Mus musculus Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes. Cardiomyocytes cl Cardiomyocyte cells (HL-1) mRNA Microarray 2013 - Exosomes/Extracellular vesicles 553 24009898 Mus musculus Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes. Cardiomyocytes cl PDGFBβ-treated-Cardiomyocyte cells (HL-1) mRNA Microarray 2013 - Exosomes/Extracellular vesicles 554 24009898 Mus musculus Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes. Cardiomyocytes cl TGFβ-treated-Cardiomyocyte cells (HL-1) mRNA Microarray 2013 - Exosomes/Extracellular vesicles 555 24046871 Homo sapiens Molecular lipidomics of exosomes released by PC-3 prostate cancer cells. Prostate cancer cells cl PC3 Lipids Mass spectrometry 2013 - Exosomes/Microvesicles 556 24069378 Homo sapiens Proteome profiling of neuroblastoma-derived exosomes reveal the expression of proteins potentially involved in tumor progression. Neuroblastoma cells cl HTLA-230 Protein Mass spectrometry 2013 - Exosomes/Membrane vesicles 559 26098775 Citrus Limon L. Citrus limon-derived nanovesicles inhibit cancer cell proliferation and suppress CML xenograft growth by inducing TRAIL-mediated cell death Lemon juice ts Lemon juice Protein Mass spectrometry [TripleTOF System] 2015 Differential centrifugation|Ultracentrifugation Microvesicles 562 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells ts monocyte-derived dendritic cells (F3 10K) Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Ultracentrifugation|OptiPrep density gradient Microvesicles 563 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells ts monocyte-derived dendritic cells (F5 10K) Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Ultracentrifugation|OptiPrep density gradient Microvesicles 564 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells ts monocyte-derived dendritic cells (F3 100K) Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Ultracentrifugation|OptiPrep density gradient Exosomes 565 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells ts monocyte-derived dendritic cells (F5 100K) Protein Mass spectrometry [LTQ ORBITRAP] 2016 Differential centrifugation|Ultracentrifugation|OptiPrep density gradient Exosomes 566 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells ts monocyte-derived dendritic cells (Igg1 PD) Protein Mass spectrometry [LTQ FUSION] 2016 Differential centrifugation|Ultracentrifugation|Immunobeads (Igg1 PD) Extracellular vesicles 567 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells ts monocyte-derived dendritic cells (Igg1 FT) Protein Mass spectrometry [LTQ FUSION] 2016 Differential centrifugation|Ultracentrifugation|Immunobeads (Igg1 FT) Extracellular vesicles 568 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells ts monocyte-derived dendritic cells (CD9 PD) Protein Mass spectrometry [LTQ FUSION] 2016 Differential centrifugation|Ultracentrifugation|Immunobeads (CD9 PD) Extracellular vesicles 569 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells ts monocyte-derived dendritic cells (CD9 FT) Protein Mass spectrometry [LTQ FUSION] 2016 Differential centrifugation|Ultracentrifugation|Immunobeads (CD9 FT) Extracellular vesicles 570 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells ts monocyte-derived dendritic cells (CD63 PD) Protein Mass spectrometry [LTQ FUSION] 2016 Differential centrifugation|Ultracentrifugation|Immunobeads (CD63 PD) Extracellular vesicles 571 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells ts monocyte-derived dendritic cells (CD63 FT) Protein Mass spectrometry [LTQ FUSION] 2016 Differential centrifugation|Ultracentrifugation|Immunobeads (CD63 FT) Extracellular vesicles 572 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells ts monocyte-derived dendritic cells (CD81 PD) Protein Mass spectrometry [LTQ FUSION] 2016 Differential centrifugation|Ultracentrifugation|Immunobeads (CD81 PD) Extracellular vesicles 573 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells ts monocyte-derived dendritic cells (CD81 FT) Protein Mass spectrometry [LTQ FUSION] 2016 Differential centrifugation|Ultracentrifugation|Immunobeads (CD81 FT) Extracellular vesicles 574 27601599 Homo sapiens Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components Breast milk ts Breast milk - normal Protein Mass spectrometry 2016 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Extracellular vesicles 575 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Breast cancer cells cl BT549 Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 576 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Breast cancer cells cl HS 578T Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 577 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Breast cancer cells cl MCF7 Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 578 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Breast cancer cells cl MDA-MB-231 Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 579 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Breast cancer cells cl MDA-MB-468 Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 580 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Brain cancer cells cl T-47D Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 581 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Brain cancer cells cl SF268 Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 582 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Brain cancer cells cl SF295 Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 583 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Brain cancer cells cl SF539 Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 584 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Brain cancer cells cl SNB-19 Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 585 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Brain cancer cells cl SNB-75 Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 586 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Brain cancer cells cl U251 Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 587 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Colorectal cancer cells cl Colo205 Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 588 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Colorectal cancer cells cl HCC 2998 Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 589 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Colorectal cancer cells cl HCT-116 Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 590 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Colorectal cancer cells cl HCT-15 Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 591 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Colorectal cancer cells cl HT29 Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 592 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Colorectal cancer cells cl KM12 Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 593 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Colorectal cancer cells cl SW620 Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 594 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Kidney cancer cells cl 786-O Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 595 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Kidney cancer cells cl A498 Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 596 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Kidney cancer cells cl ACHN Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 597 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Kidney cancer cells cl CAKI Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 598 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Kidney cancer cells cl RXF 393 Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 599 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Kidney cancer cells cl SN12C Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 600 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Kidney cancer cells cl TK-10 Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 601 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Kidney cancer cells cl UO-31 Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 602 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Leukemia cells cl CCRF-CEM Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 603 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Leukemia cells cl HL-60 Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 604 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Leukemia cells cl K562 Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 605 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Leukemia cells cl MOLT-4 Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 606 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Leukemia cells cl RPMI-8226 Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 607 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Leukemia cells cl SR Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 608 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Lung cancer cells cl A549 Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 609 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Lung cancer cells cl EKVX Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 610 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Lung cancer cells cl HOP-62 Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 611 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Lung cancer cells cl HOP-92 Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 612 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Lung cancer cells cl NCI-H226 Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 613 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Lung cancer cells cl NCI-H23 Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 614 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Lung cancer cells cl NCI-H322M Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 615 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Lung cancer cells cl NCI-H460 Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 616 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Lung cancer cells cl NCI-H522 Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 617 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Melanoma cells cl LOX IMVI Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 618 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Melanoma cells cl M14 Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 619 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Melanoma cells cl MALME-3M Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 620 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Melanoma cells cl MDA-MB-435 Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 621 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Melanoma cells cl SK-MEL-2 Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 622 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Melanoma cells cl SK-MEL-28 Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 623 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Melanoma cells cl SK-MEL-5 Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 624 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Melanoma cells cl UACC-257 Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 625 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Melanoma cells cl UACC-62 Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 626 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Ovarian cancer cells cl IGROV1 Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 627 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Ovarian cancer cells cl OVCAR-3 Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 628 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Ovarian cancer cells cl OVCAR-4 Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 629 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Ovarian cancer cells cl OVCAR-5 Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 630 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Ovarian cancer cells cl OVCAR-8 Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 631 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Ovarian cancer cells cl SK-OV-3 Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 632 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Ovarian cancer cells cl NCI-ADR-RES Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 633 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Prostate cancer cells cl DU145 Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 634 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Prostate cancer cells cl PC-3 Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Polymer-based precipitation|Ultracentrifugation Extracellular vesicles 650 29188495 Homo sapiens Protein Biomarkers and Neuroproteomics Characterization of Microvesicles/Exosomes from Human Cerebrospinal Fluid Following Traumatic Brain Injury. Cerebrospinal fluid ts Cerebrospinal fluid - Normal Protein Mass spectrometry 2018 Differential centrifugation|Ultracentrifugation|Sonication|Filtration Extracellular vesicles 651 29188495 Homo sapiens Protein Biomarkers and Neuroproteomics Characterization of Microvesicles/Exosomes from Human Cerebrospinal Fluid Following Traumatic Brain Injury. Cerebrospinal fluid ts Cerebrospinal Fluid - Traumatic brain injury Protein Mass spectrometry|Western blotting 2018 Differential centrifugation|Ultracentrifugation|Sonication|Filtration Extracellular vesicles 652 28290293 Homo sapiens Comparative proteomic analysis of milk-derived exosomes in human and bovine colostrum and mature milk samples by iTRAQ-coupled LC-MS/MS. Breast milk ts Colostrum Protein Mass spectrometry 2017 Differential centrifugation|Ultracentrifugation|Filtration|Density gradient centrifugation Exosomes 653 28290293 Homo sapiens Comparative proteomic analysis of milk-derived exosomes in human and bovine colostrum and mature milk samples by iTRAQ-coupled LC-MS/MS. Breast milk ts Mature milk Protein Mass spectrometry 2017 Differential centrifugation|Ultracentrifugation|Filtration|Density gradient centrifugation Exosomes 654 28290293 Bos taurus Comparative proteomic analysis of milk-derived exosomes in human and bovine colostrum and mature milk samples by iTRAQ-coupled LC-MS/MS. Bovine milk ts Colostrum Protein Mass spectrometry 2017 Differential centrifugation|Ultracentrifugation|Filtration|Density gradient centrifugation Exosomes 655 28290293 Bos taurus Comparative proteomic analysis of milk-derived exosomes in human and bovine colostrum and mature milk samples by iTRAQ-coupled LC-MS/MS. Bovine milk ts Mature milk Protein Mass spectrometry 2017 Differential centrifugation|Ultracentrifugation|Filtration|Density gradient centrifugation Exosomes 656 28753793 Homo sapiens MicroRNAs in Serum Exosomes as Potential Biomarkers in Clear-cell Renal Cell Carcinoma. Serum ts Preoperative patient serum- collected 1 day before tumor resection miRNA RT-PCR|qPCR 2016 Total Exosome Isolation Kit|Differential centrifugation|Ultracentrifugation|Immunobeads (EpCAM) Exosomes 657 28753793 Homo sapiens MicroRNAs in Serum Exosomes as Potential Biomarkers in Clear-cell Renal Cell Carcinoma. Serum ts Postoperative patient serum- collected 7 days after tumor resection miRNA RT-PCR|qPCR 2016 Total Exosome Isolation Kit|Differential centrifugation|Ultracentrifugation|Immunobeads (EpCAM) Exosomes 658 28753793 Homo sapiens MicroRNAs in Serum Exosomes as Potential Biomarkers in Clear-cell Renal Cell Carcinoma. Serum ts Normal serum miRNA RT-PCR|qPCR 2016 Total Exosome Isolation Kit|Differential centrifugation|Ultracentrifugation|Immunobeads (EpCAM) Exosomes 659 29982104 Mus musculus NRP-1 targeted and cargo-loaded exosomes facilitate simultaneous imaging and therapy of glioma in vitro and in vivo. Macrophage cl Raw 264.7 Protein Western blotting 2018 Differential centrifugation|Ultracentrifugation|Ultrafiltration Exosomes 660 29964051 Homo sapiens Cell-free therapy based on adipose tissue stem cell-derived exosomes promotes wound healing via the PI3K/Akt signaling pathway Adipose tissue-derived stem cells cl Normal ADSC's Protein Western blotting|Flow cytometry 2018 Differential centrifugation|Ultracentrifugation Exosomes 661 29956871 Homo sapiens Expression analysis of extracellular microRNA in bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis Bronchoalveolar lavage fluid ts Sarcoidosis patients- CXR.I Protein Western blotting 2018 Differential centrifugation|Ultracentrifugation|Filtration Exosomes 662 29956871 Homo sapiens Expression analysis of extracellular microRNA in bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis Bronchoalveolar lavage fluid ts Sarcoidosis patients- CXR.I Protein Western blotting 2018 Differential centrifugation|Ultracentrifugation|Filtration Microvesicles 663 29956871 Homo sapiens Expression analysis of extracellular microRNA in bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis Bronchoalveolar lavage fluid ts Sarcoidosis patients- CXR.II Protein Western blotting 2018 Differential centrifugation|Ultracentrifugation|Filtration Exosomes 664 29956871 Homo sapiens Expression analysis of extracellular microRNA in bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis Bronchoalveolar lavage fluid ts Sarcoidosis patients- CXR.II Protein Western blotting 2018 Differential centrifugation|Ultracentrifugation|Filtration Microvesicles 665 29956871 Homo sapiens Expression analysis of extracellular microRNA in bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis Bronchoalveolar lavage fluid ts Sarcoidosis patients- CXR.I miRNA RT-PCR|qPCR 2018 Differential centrifugation|Ultracentrifugation|Filtration Exosomes 666 29956871 Homo sapiens Expression analysis of extracellular microRNA in bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis Bronchoalveolar lavage fluid ts Sarcoidosis patients- CXR.I miRNA RT-PCR|qPCR 2018 Differential centrifugation|Ultracentrifugation|Filtration Microvesicles 667 29956871 Homo sapiens Expression analysis of extracellular microRNA in bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis Bronchoalveolar lavage fluid ts Sarcoidosis patients- CXR.II miRNA RT-PCR|qPCR 2018 Differential centrifugation|Ultracentrifugation|Filtration Exosomes 668 29956871 Homo sapiens Expression analysis of extracellular microRNA in bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis Bronchoalveolar lavage fluid ts Sarcoidosis patients- CXR.II miRNA RT-PCR|qPCR 2018 Differential centrifugation|Ultracentrifugation|Filtration Microvesicles 669 29953960 Homo sapiens Exosomes derived from calcium oxalate-exposed macrophages enhance IL-8 production from renal cells, neutrophil migration and crystal invasion through extracellular matrix. Macrophage cl U937- Human monocytic cell line differentiated to macrophages (Control) Protein Western blotting 2018 Microfiltration|Differential centrifugation|Ultracentrifugation Exosomes 670 29953960 Homo sapiens Exosomes derived from calcium oxalate-exposed macrophages enhance IL-8 production from renal cells, neutrophil migration and crystal invasion through extracellular matrix. Macrophage cl U937- Human monocytic cell line differentiated to macrophages (COM treated) Protein Western blotting 2018 Microfiltration|Differential centrifugation|Ultracentrifugation Exosomes 671 29953960 Homo sapiens Exosomes derived from calcium oxalate-exposed macrophages enhance IL-8 production from renal cells, neutrophil migration and crystal invasion through extracellular matrix. Macrophage cl U937- Human monocytic cell line differentiated to macrophages (Control) Protein Mass spectrometry 2018 Microfiltration|Differential centrifugation|Ultracentrifugation Exosomes 672 29953960 Homo sapiens Exosomes derived from calcium oxalate-exposed macrophages enhance IL-8 production from renal cells, neutrophil migration and crystal invasion through extracellular matrix. Macrophage cl U937- Human monocytic cell line differentiated to macrophages (COM treated) Protein Mass spectrometry 2018 Microfiltration|Differential centrifugation|Ultracentrifugation Exosomes 673 29953960 Homo sapiens Exosomes derived from calcium oxalate-exposed macrophages enhance IL-8 production from renal cells, neutrophil migration and crystal invasion through extracellular matrix. Macrophage cl U937- Human monocytic cell line differentiated to macrophages (Control) Protein Mass spectrometry|Western blotting 2018 Microfiltration|Differential centrifugation|Ultracentrifugation Exosomes 674 29953960 Homo sapiens Exosomes derived from calcium oxalate-exposed macrophages enhance IL-8 production from renal cells, neutrophil migration and crystal invasion through extracellular matrix. Macrophage cl U937- Human monocytic cell line differentiated to macrophages (COM treated) Protein Mass spectrometry|Western blotting 2018 Microfiltration|Differential centrifugation|Ultracentrifugation Exosomes 675 29951053 Mus musculus Immunoregulatory Effects of Myeloid-Derived Suppressor Cell Exosomes in Mouse Model of Autoimmune Alopecia Areata. Myeloid-derived suppressor cells cl In-vitro- Alopecia areata affected C3H/HeJ mice BMC derived Protein FACS 2018 Ultracentrifugation|Density gradient centrifugation Exosomes 676 29951053 Mus musculus Immunoregulatory Effects of Myeloid-Derived Suppressor Cell Exosomes in Mouse Model of Autoimmune Alopecia Areata. Myeloid-derived suppressor cells cl Ex-vivo- Alopecia areata affected C3H/HeJ mice Protein FACS 2018 Ultracentrifugation|Density gradient centrifugation Exosomes 677 29951053 Mus musculus Immunoregulatory Effects of Myeloid-Derived Suppressor Cell Exosomes in Mouse Model of Autoimmune Alopecia Areata. Dendritic cells cl In-vitro- Alopecia areata affected C3H/HeJ mice BMC derived Protein FACS 2018 Ultracentrifugation|Density gradient centrifugation Exosomes 678 29951053 Mus musculus Immunoregulatory Effects of Myeloid-Derived Suppressor Cell Exosomes in Mouse Model of Autoimmune Alopecia Areata. Myeloid-derived suppressor cells cl In-vitro- Alopecia areata affected C3H/HeJ mice BMC derived Protein Mass spectrometry 2018 Ultracentrifugation|Density gradient centrifugation Exosomes 679 29951053 Mus musculus Immunoregulatory Effects of Myeloid-Derived Suppressor Cell Exosomes in Mouse Model of Autoimmune Alopecia Areata. Myeloid-derived suppressor cells cl Ex-vivo- Alopecia areata affected C3H/HeJ mice Protein Mass spectrometry 2018 Ultracentrifugation|Density gradient centrifugation Exosomes 680 29148239 Homo sapiens Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. Umblical cord mesenchymal stem cells cl Preterm newborns- replicate 1 Protein Mass spectrometry 2018 Differential centrifugation|Ultracentrifugation|Sonication|Filtration Microvesicles 681 29148239 Homo sapiens Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. Umblical cord mesenchymal stem cells cl Preterm newborns- replicate 2 Protein Mass spectrometry 2018 Differential centrifugation|Ultracentrifugation|Sonication|Filtration Microvesicles 682 29148239 Homo sapiens Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. Umblical cord mesenchymal stem cells cl Preterm newborns- replicate 3 Protein Mass spectrometry 2018 Differential centrifugation|Ultracentrifugation|Sonication|Filtration Microvesicles 683 29148239 Homo sapiens Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. Umblical cord mesenchymal stem cells cl Term infants- replicate 1 Protein Mass spectrometry 2018 Differential centrifugation|Ultracentrifugation|Sonication|Filtration Microvesicles 684 29148239 Homo sapiens Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. Umblical cord mesenchymal stem cells cl Term infants- replicate 2 Protein Mass spectrometry 2018 Differential centrifugation|Ultracentrifugation|Sonication|Filtration Microvesicles 685 29148239 Homo sapiens Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. Umblical cord mesenchymal stem cells cl Term infants- replicate 3 Protein Mass spectrometry 2018 Differential centrifugation|Ultracentrifugation|Sonication|Filtration Microvesicles 686 29148239 Homo sapiens Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. Umblical cord mesenchymal stem cells cl Preterm newborns Protein Western blotting 2018 Differential centrifugation|Ultracentrifugation|Sonication|Filtration Microvesicles 687 29148239 Homo sapiens Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. Umblical cord mesenchymal stem cells cl Term infants Protein Western blotting 2018 Differential centrifugation|Ultracentrifugation|Sonication|Filtration Microvesicles 688 28170197 Homo sapiens Enhanced Cardioprotection by Human Endometrium Mesenchymal Stem Cells Driven by Exosomal MicroRNA-21 Endometrium-derived mesenchymal stem cells cl EnMSC's miRNA Microarray|qRT-PCR 2017 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 689 28170197 Homo sapiens Enhanced Cardioprotection by Human Endometrium Mesenchymal Stem Cells Driven by Exosomal MicroRNA-21 Adipose-derived mesenchymal stem cells cl AdMSC'S miRNA Microarray|qRT-PCR 2017 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 690 28170197 Homo sapiens Enhanced Cardioprotection by Human Endometrium Mesenchymal Stem Cells Driven by Exosomal MicroRNA-21 Bone marrow mesenchymal stem cells cl BMMSC's miRNA Microarray|qRT-PCR 2017 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 691 28170197 Homo sapiens Enhanced Cardioprotection by Human Endometrium Mesenchymal Stem Cells Driven by Exosomal MicroRNA-21 Endometrium-derived mesenchymal stem cells cl EnMSC's Protein Western blotting 2017 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 692 28170197 Homo sapiens Enhanced Cardioprotection by Human Endometrium Mesenchymal Stem Cells Driven by Exosomal MicroRNA-21 Adipose-derived mesenchymal stem cells cl AdMSC'S Protein Western blotting 2017 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 693 28170197 Homo sapiens Enhanced Cardioprotection by Human Endometrium Mesenchymal Stem Cells Driven by Exosomal MicroRNA-21 Bone marrow mesenchymal stem cells cl BMMSC's Protein Western blotting 2017 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 694 28842968 Homo sapiens Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles. Colorectal cancer cells cl LIM1215- insulin induced Protein Western blotting 2017 Differential centrifugation|Ultracentrifugation Microvesicles 695 28842968 Homo sapiens Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles. Colorectal cancer cells cl LIM1215- non-induced Protein Western blotting 2017 Differential centrifugation|Ultracentrifugation Microvesicles 696 28842968 Homo sapiens Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles. Colorectal cancer cells cl LIM1215- insulin induced Protein Mass spectrometry 2017 Differential centrifugation|Ultracentrifugation Microvesicles 697 28842968 Homo sapiens Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles. Colorectal cancer cells cl LIM1215- non-induced Protein Mass spectrometry 2017 Differential centrifugation|Ultracentrifugation Microvesicles 698 28811610 Homo sapiens Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. T cells cl Jurkat cells - Drug treated Protein FACS 2017 Differential centrifugation|Filtration|Ultracentrifugation|Density gradient centrifugation Exosomes 699 28811610 Homo sapiens Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. T cells cl Jurkat cells - Untreated Protein FACS 2017 Differential centrifugation|Filtration|Ultracentrifugation|Density gradient centrifugation Exosomes 700 28811610 Homo sapiens Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. T cells cl Jurkat cells - Drug treated Protein FACS 2017 Differential centrifugation|Filtration|Ultracentrifugation|Density gradient centrifugation Microvesicles 701 28811610 Homo sapiens Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. T cells cl Jurkat cells - Untreated Protein FACS 2017 Differential centrifugation|Filtration|Ultracentrifugation|Density gradient centrifugation Microvesicles 702 28811610 Homo sapiens Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. T cells cl Jurkat cells - Drug treated Protein FACS 2017 Differential centrifugation|Filtration|Ultracentrifugation|Density gradient centrifugation Apoptotic bodies 703 28811610 Homo sapiens Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. T cells cl Jurkat cells - Untreated Protein FACS 2017 Differential centrifugation|Filtration|Ultracentrifugation|Density gradient centrifugation Apoptotic bodies 704 28811610 Homo sapiens Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. T cells cl Jurkat cells - Control Protein FACS 2017 Differential centrifugation|Filtration|Ultracentrifugation|Density gradient centrifugation Microvesicles/Apoptotic bodies 705 28811610 Homo sapiens Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. T cells cl Jurkat cells - Activated Protein FACS 2017 Differential centrifugation|Filtration|Ultracentrifugation|Density gradient centrifugation Microvesicles/Apoptotic bodies 706 28811610 Homo sapiens Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. T cells cl Jurkat cells - Apoptotic Protein FACS 2017 Differential centrifugation|Filtration|Ultracentrifugation|Density gradient centrifugation Microvesicles/Apoptotic bodies 707 28811610 Homo sapiens Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. T cells cl Jurkat cells - Control Protein Mass spectrometry 2017 Differential centrifugation|Filtration|Ultracentrifugation|Density gradient centrifugation Exosomes 708 28811610 Homo sapiens Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. T cells cl Jurkat cells - Control Protein Mass spectrometry 2017 Differential centrifugation|Filtration|Ultracentrifugation|Density gradient centrifugation Microvesicles 709 28811610 Homo sapiens Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. T cells cl Jurkat cells - Control Protein Mass spectrometry 2017 Differential centrifugation|Filtration|Ultracentrifugation|Density gradient centrifugation Apoptotic bodies 710 28811610 Homo sapiens Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. T cells cl Jurkat cells - Activated Protein Mass spectrometry 2017 Differential centrifugation|Filtration|Ultracentrifugation|Density gradient centrifugation Exosomes 711 28811610 Homo sapiens Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. T cells cl Jurkat cells - Activated Protein Mass spectrometry 2017 Differential centrifugation|Filtration|Ultracentrifugation|Density gradient centrifugation Microvesicles 712 28811610 Homo sapiens Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. T cells cl Jurkat cells - Activated Protein Mass spectrometry 2017 Differential centrifugation|Filtration|Ultracentrifugation|Density gradient centrifugation Apoptotic bodies 713 28811610 Homo sapiens Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. T cells cl Jurkat cells - Apoptotic Protein Mass spectrometry 2017 Differential centrifugation|Filtration|Ultracentrifugation|Density gradient centrifugation Exosomes 714 28811610 Homo sapiens Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. T cells cl Jurkat cells - Apoptotic Protein Mass spectrometry 2017 Differential centrifugation|Filtration|Ultracentrifugation|Density gradient centrifugation Microvesicles 715 28811610 Homo sapiens Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. T cells cl Jurkat cells - Apoptotic Protein Mass spectrometry 2017 Differential centrifugation|Filtration|Ultracentrifugation|Density gradient centrifugation Apoptotic bodies 716 26317203 Homo sapiens Progression of Osteosarcoma from a Non-Metastatic to a Metastatic Phenotype Is Causally Associated with Activation of an Autocrine and Paracrine uPA Axis. Osteosarcoma cells cl KHOS- bone osteosarcoma cells Protein Western blotting 2015 Differential centrifugation|Ultracentrifugation Exosomes 717 26148937 Homo sapiens Proteomics profiling of cholangiocarcinoma exosomes: A potential role of oncogenic protein transferring in cancer progression. Cholangiocytes cl H69 Protein Western blotting 2015 Differential centrifugation|Ultracentrifugation|Filtration Exosomes 718 26148937 Homo sapiens Proteomics profiling of cholangiocarcinoma exosomes: A potential role of oncogenic protein transferring in cancer progression. Cholangiocarcinoma cells cl KKU-100 Protein Western blotting 2015 Differential centrifugation|Ultracentrifugation|Filtration Exosomes 719 26148937 Homo sapiens Proteomics profiling of cholangiocarcinoma exosomes: A potential role of oncogenic protein transferring in cancer progression. Cholangiocarcinoma cells cl KKU-M213 Protein Western blotting 2015 Differential centrifugation|Ultracentrifugation|Filtration Exosomes 720 26148937 Homo sapiens Proteomics profiling of cholangiocarcinoma exosomes: A potential role of oncogenic protein transferring in cancer progression. Cholangiocytes cl H69 Protein Mass spectrometry 2015 Differential centrifugation|Ultracentrifugation|Filtration Exosomes 721 26148937 Homo sapiens Proteomics profiling of cholangiocarcinoma exosomes: A potential role of oncogenic protein transferring in cancer progression. Cholangiocarcinoma cells cl KKU-M213 Protein Mass spectrometry 2015 Differential centrifugation|Ultracentrifugation|Filtration Exosomes 722 25802036 Homo sapiens Glioblastoma-derived extracellular vesicles modify the phenotype of monocytic cells. Glioblastoma cells cl U87.MG/EGFRvIII Protein Mass spectrometry 2015 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 723 25802036 Homo sapiens Glioblastoma-derived extracellular vesicles modify the phenotype of monocytic cells. Glioblastoma cells cl GS184 Protein Mass spectrometry 2015 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 724 25471207 Homo sapiens Intraluminal proteome and peptidome of human urinary extracellular vesicles. Urine ts Normal crude urine Protein Western blotting 2015 Differential centrifugation|Hydrostatic filtration dialysis|Ultrafiltration Exosomes 725 25471207 Homo sapiens Intraluminal proteome and peptidome of human urinary extracellular vesicles. Urine ts Normal crude urine- Trypsinized Protein Mass spectrometry 2015 Differential centrifugation|Hydrostatic filtration dialysis|Ultrafiltration Exosomes 726 25471207 Homo sapiens Intraluminal proteome and peptidome of human urinary extracellular vesicles. Urine ts Normal crude urine- non-trypsinized Protein Mass spectrometry 2015 Differential centrifugation|Hydrostatic filtration dialysis|Ultrafiltration Exosomes 727 25359493 Homo sapiens Proteomic signatures of extracellular vesicles secreted by nonmineralizing and mineralizing human osteoblasts and stimulation of tumor cell growth. Osteoblasts cl MOB's- dexamethasone treated (day 5) Protein Western blotting 2015 Differential centrifugation|Ultracentrifugation Matrix vesicles 728 25359493 Homo sapiens Proteomic signatures of extracellular vesicles secreted by nonmineralizing and mineralizing human osteoblasts and stimulation of tumor cell growth. Osteoblasts cl MOB's- dexamethasone-treated (day 12) Protein Western blotting 2015 Differential centrifugation|Ultracentrifugation Matrix vesicles 729 25359493 Homo sapiens Proteomic signatures of extracellular vesicles secreted by nonmineralizing and mineralizing human osteoblasts and stimulation of tumor cell growth. Osteoblasts cl MOB's- dexamethasone-treated (day 19) Protein Western blotting 2015 Differential centrifugation|Ultracentrifugation Matrix vesicles 730 25359493 Homo sapiens Proteomic signatures of extracellular vesicles secreted by nonmineralizing and mineralizing human osteoblasts and stimulation of tumor cell growth. Osteoblasts cl NMOB's- non-dexamethasone-treated (day 5) Protein Western blotting 2015 Differential centrifugation|Ultracentrifugation Matrix vesicles 731 25359493 Homo sapiens Proteomic signatures of extracellular vesicles secreted by nonmineralizing and mineralizing human osteoblasts and stimulation of tumor cell growth. Osteoblasts cl NMOB's- non-dexamethasone-treated (day 12) Protein Western blotting 2015 Differential centrifugation|Ultracentrifugation Matrix vesicles 732 25359493 Homo sapiens Proteomic signatures of extracellular vesicles secreted by nonmineralizing and mineralizing human osteoblasts and stimulation of tumor cell growth. Osteoblasts cl NMOB's- non-dexamethasone-treated (day 19) Protein Western blotting 2015 Differential centrifugation|Ultracentrifugation Matrix vesicles 733 25359493 Homo sapiens Proteomic signatures of extracellular vesicles secreted by nonmineralizing and mineralizing human osteoblasts and stimulation of tumor cell growth. Osteoblasts cl MOB's- dexamethasone treated Protein Mass spectrometry 2015 Differential centrifugation|Ultracentrifugation Matrix vesicles 734 25359493 Homo sapiens Proteomic signatures of extracellular vesicles secreted by nonmineralizing and mineralizing human osteoblasts and stimulation of tumor cell growth. Osteoblasts cl NMOB's- non-dexamethasone-treated Protein Mass spectrometry 2015 Differential centrifugation|Ultracentrifugation Matrix vesicles 735 25285581 Mus musculus Ubiquitinated proteins in exosomes secreted by myeloid-derived suppressor cells. Myeloid-derived suppressor cells cl in-gel tryptic digestion Protein Mass spectrometry 2014 Differential centrifugation|Ultracentrifugation Exosomes 736 25285581 Mus musculus Ubiquitinated proteins in exosomes secreted by myeloid-derived suppressor cells. Myeloid-derived suppressor cells cl tryptic digestion in solution Protein Mass spectrometry 2014 Differential centrifugation|Ultracentrifugation Exosomes 737 25220352 Mus musculus Surface functionalization of exosomes using click chemistry. Breast cancer cells cl 4T1 Protein Mass spectrometry 2014 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 738 25157233 Homo sapiens Extravillous trophoblast cells-derived exosomes promote vascular smooth muscle cell migration. Placenta choriocarcinoma cells cl JEG-3 Protein Mass spectrometry 2014 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 739 25157233 Homo sapiens Extravillous trophoblast cells-derived exosomes promote vascular smooth muscle cell migration. Placenta cl HTR-8/Svneo Protein Mass spectrometry 2014 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 740 25157233 Homo sapiens Extravillous trophoblast cells-derived exosomes promote vascular smooth muscle cell migration. Placenta choriocarcinoma cells cl JEG-3 Protein Western blotting 2014 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 741 25157233 Homo sapiens Extravillous trophoblast cells-derived exosomes promote vascular smooth muscle cell migration. Placenta cl HTR-8/Svneo Protein Western blotting 2014 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 742 28524762 Rattus norvegicus Exosomes promote restoration after an experimental animal model of intracerebral hemorrhage Mesenchymal stem cells ts Allogenic adipose tissue Protein Western blotting|Immunofluorescence 2018 miRCURY Exosome Isolation Kit Exosomes 743 29988836 Homo sapiens Ultrafiltration and size exclusion chromatography combined with asymmetrical-flow field-flow fractionation for the isolation and characterisation of extracellular vesicles from urine Urine ts Urine - Fraction 7 Protein Western blotting 2018 Filtration|Size exclusion chromatography Extracellular vesicles 744 29988836 Homo sapiens Ultrafiltration and size exclusion chromatography combined with asymmetrical-flow field-flow fractionation for the isolation and characterisation of extracellular vesicles from urine Urine ts Urine - Fraction 8 Protein Western blotting 2018 Filtration|Size exclusion chromatography Extracellular vesicles 745 29988836 Homo sapiens Ultrafiltration and size exclusion chromatography combined with asymmetrical-flow field-flow fractionation for the isolation and characterisation of extracellular vesicles from urine Urine ts Urine - Fraction 9 Protein Western blotting 2018 Filtration|Size exclusion chromatography Extracellular vesicles 746 29988836 Homo sapiens Ultrafiltration and size exclusion chromatography combined with asymmetrical-flow field-flow fractionation for the isolation and characterisation of extracellular vesicles from urine Urine ts Urine - Fraction 10 Protein Western blotting 2018 Filtration|Size exclusion chromatography Extracellular vesicles 747 29988836 Homo sapiens Ultrafiltration and size exclusion chromatography combined with asymmetrical-flow field-flow fractionation for the isolation and characterisation of extracellular vesicles from urine Urine ts Urine - Fraction 11 Protein Western blotting 2018 Filtration|Size exclusion chromatography Extracellular vesicles 748 29988836 Homo sapiens Ultrafiltration and size exclusion chromatography combined with asymmetrical-flow field-flow fractionation for the isolation and characterisation of extracellular vesicles from urine Urine ts Urine - Fraction 12 Protein Western blotting 2018 Filtration|Size exclusion chromatography Extracellular vesicles 749 29988836 Homo sapiens Ultrafiltration and size exclusion chromatography combined with asymmetrical-flow field-flow fractionation for the isolation and characterisation of extracellular vesicles from urine Urine ts Urine - Fraction 13 Protein Western blotting 2018 Filtration|Size exclusion chromatography Extracellular vesicles 750 29988836 Homo sapiens Ultrafiltration and size exclusion chromatography combined with asymmetrical-flow field-flow fractionation for the isolation and characterisation of extracellular vesicles from urine Urine ts Urine - Fraction 14 Protein Western blotting 2018 Filtration|Size exclusion chromatography Extracellular vesicles 751 29988836 Homo sapiens Ultrafiltration and size exclusion chromatography combined with asymmetrical-flow field-flow fractionation for the isolation and characterisation of extracellular vesicles from urine Urine ts Urine - Fraction 8 and 9 pooled Protein Mass spectrometry 2018 Filtration|Size exclusion chromatography Extracellular vesicles 752 29963269 Homo sapiens Mining of potential microRNAs with clinical correlation - regulation of syndecan-1 expression by miR-122-5p altered mobility of breast cancer cells and possible correlation with liver injury Hepatoma cells cl Huh-7 Protein Western blotting 2018 Total Exosome Isolation Kit|Differential centrifugation Exosomes 753 29963269 Homo sapiens Mining of potential microRNAs with clinical correlation - regulation of syndecan-1 expression by miR-122-5p altered mobility of breast cancer cells and possible correlation with liver injury Hepatoma cells cl Huh-7 miRNA PCR 2018 Total Exosome Isolation Kit|Differential centrifugation Exosomes 754 29963269 Homo sapiens Mining of potential microRNAs with clinical correlation - regulation of syndecan-1 expression by miR-122-5p altered mobility of breast cancer cells and possible correlation with liver injury Hepatoma cells cl Hep3B Protein Western blotting 2018 Total Exosome Isolation Kit|Differential centrifugation Exosomes 755 29963269 Homo sapiens Mining of potential microRNAs with clinical correlation - regulation of syndecan-1 expression by miR-122-5p altered mobility of breast cancer cells and possible correlation with liver injury Hepatoma cells cl Hep3B miRNA PCR 2018 Total Exosome Isolation Kit|Differential centrifugation Exosomes 756 28357077 Mus musculus Circulating osteocyte-derived exosomes contain miRNAs which are enriched in exosomes from MLO-Y4 cells Plasma ts Plasma - WT C57BL/6 mouse miRNA Microarray 2017 Total Exosome Isolation Kit|Differential centrifugation Exosomes 757 28357077 Mus musculus Circulating osteocyte-derived exosomes contain miRNAs which are enriched in exosomes from MLO-Y4 cells Plasma ts Plasma - C57BL/6 DMP1 TR Tg mouse miRNA Microarray 2017 Total Exosome Isolation Kit|Differential centrifugation Exosomes 758 28357077 Mus musculus Circulating osteocyte-derived exosomes contain miRNAs which are enriched in exosomes from MLO-Y4 cells Osteocytes cl MLO-Y4 miRNA Microarray 2017 Total Exosome Isolation Kit|Differential centrifugation Exosomes 759 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes ts Head kidney leukocytes (HKLs) Protein Mass spectrometry|Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 760 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes ts Head kidney leukocytes (HKLs) - ODN 2006PS stimulated Protein Mass spectrometry|Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 761 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes ts Head kidney leukocytes (HKLs) - ODN 2006PS stimulated - Fraction 5 Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation|Density gradient centrifugation Exosomes 762 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes ts Head kidney leukocytes (HKLs) - ODN 2006PS stimulated - Fraction 6 Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation|Density gradient centrifugation Exosomes 763 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes ts Head kidney leukocytes (HKLs) - ODN 2006PS stimulated - Fraction 7 Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation|Density gradient centrifugation Exosomes 764 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes ts Head kidney leukocytes (HKLs) - Fish 1 Protein Mass spectrometry 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 765 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes ts Head kidney leukocytes (HKLs) - Fish 3 Protein Mass spectrometry 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 766 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes ts Head kidney leukocytes (HKLs) - Fish 2 Protein Mass spectrometry 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 767 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes ts Head kidney leukocytes (HKLs) - ODN 2006PS stimulated - Fish 1 Protein Mass spectrometry 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 768 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes ts Head kidney leukocytes (HKLs) - ODN 2006PS stimulated - Fish 3 Protein Mass spectrometry 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 769 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes ts Head kidney leukocytes (HKLs) - ODN 2006PS stimulated - Fish 2 Protein Mass spectrometry 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 770 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes ts Head kidney leukocytes (HKLs) - ODN 2006PS stimulated - Fish 4 Protein Mass spectrometry 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 771 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes ts Head kidney leukocytes (HKLs) - R848 treated Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 772 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes ts Head kidney leukocytes (HKLs) - poly(I:C) treated Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 773 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes ts Head kidney leukocytes (HKLs) Protein Western blotting 2018 Differential centrifugation Apoptotic bodies 774 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes ts Head kidney leukocytes (HKLs) - ODN 2006PS stimulated Protein Western blotting 2018 Differential centrifugation Apoptotic bodies 775 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes ts Head kidney leukocytes (HKLs) Protein Western blotting 2018 Differential centrifugation Microvesicles 776 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes ts Head kidney leukocytes (HKLs) - ODN 2006PS stimulated Protein Western blotting 2018 Differential centrifugation Microvesicles 777 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes ts Head kidney leukocytes (HKLs) - ODN 2137PS stimulated Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 778 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes ts Head kidney leukocytes (HKLs) - ODN 2216PO/PS stimulated Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 779 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes ts Head kidney leukocytes (HKLs) - ODN 2137PS stimulated Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 780 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes ts Head kidney leukocytes (HKLs) - ODN 2137PO stimulated Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 781 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes ts Head kidney leukocytes (HKLs) - S. salar genomic DNA stimulated Protein Mass spectrometry|Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 782 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes ts Head kidney leukocytes (HKLs) - ChQ treated with ODN 2006PS stimulation Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 783 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes ts Peripheral blood leukocytes (PBLs) Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 784 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes ts Peripheral blood leukocytes (PBLs) - ODN 2006PS stimulated Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 785 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Epithelial cells cl ASK - ODN 2006PS stimulated Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 786 29953723 Oncorhynchus tshawytscha Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Embryonic cells cl CHSE-214 - ODN 2006PS stimulated Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 787 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Embryonic kidney cells cl HEK293T Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 788 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Embryonic kidney cells cl HEK293T - Fraction 4 Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation|Density gradient centrifugation Exosomes 789 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Embryonic kidney cells cl HEK293T - Fraction 5 Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation|Density gradient centrifugation Exosomes 790 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Embryonic kidney cells cl HEK293T - S. salar genomic DNA stimulated Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 791 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Embryonic kidney cells cl HEK293T - E. coli genomic DNA stimulated Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 792 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Embryonic kidney cells cl HEK293T - condition medium collected after 5 min with S. salar genomic DNA stimulation Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 793 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Embryonic kidney cells cl HEK293T - condition medium collected after 45 min without S.salar genomic DNA stimulation Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 794 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Embryonic kidney cells cl HEK293T - condition medium collected after 45 min with S. salar genomic DNA stimulation Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 795 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Embryonic kidney cells cl HEK293T - condition medium collected after 60 min Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 796 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Embryonic kidney cells cl HEK293T - on ice with S. salar genomic DNA stimulation Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 797 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Embryonic kidney cells cl HEK293T - DNase I treated Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 798 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Embryonic kidney cells cl HEK293T - DNase I treated with S. salar genomic DNA stimulation Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 799 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Embryonic kidney cells cl HEK293T Protein Western blotting 2018 Differential centrifugation Microvesicles 800 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Embryonic kidney cells cl HEK293T - ODN 2137PS stimulated Protein Western blotting 2018 Differential centrifugation Microvesicles 801 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Embryonic kidney cells cl HEK293T - ODN 2137PS stimulated Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 802 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types T cells cl Jurkat cells Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 803 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types T cells cl Jurkat cells - ODN 2395PS stimulated Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 804 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types T cells cl Jurkat cells - S. salar genomic DNA stimulated Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 805 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types T cells cl Jurkat cells - PD184352 treated Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 806 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types T cells cl Jurkat cells - PD184352 treated with S. salar genomic DNA stimulation Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 807 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types T cells cl Jurkat cells - Heparin treated Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 808 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types T cells cl Jurkat cells - PD184352 and Heparin treated Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 809 29932869 Mus musculus Exosomes derived from high-glucose-stimulated Schwann cells promote development of diabetic peripheral neuropathy Schwann cells ts Schwann cells protein Western blotting 2018 Filtration|Differential centrifugation|Ultracentrifugation Exosomes 810 29932869 Mus musculus Exosomes derived from high-glucose-stimulated Schwann cells promote development of diabetic peripheral neuropathy Schwann cells ts Schwann cells - 30 mM glucose treated miRNA RT-PCR 2018 Filtration|Differential centrifugation|Ultracentrifugation Exosomes 811 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes ts Cardiomyocyte cells - exosomes incubated at 4°C Protein Western blotting 2013 Differential centrifugation|Filtration|ExoQuick|Ultracentrifugation Exosomes 812 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes ts Cardiomyocyte cells - exosomes incubated at 25°C Protein Western blotting 2013 Differential centrifugation|Filtration|ExoQuick|Ultracentrifugation Exosomes 813 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes ts Cardiomyocyte cells - exosomes incubated at 37°C Protein Western blotting 2013 Differential centrifugation|Filtration|ExoQuick|Ultracentrifugation Exosomes 814 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes ts Cardiomyocyte cells - exosomes incubated at 42°C Protein Western blotting 2013 Differential centrifugation|Filtration|ExoQuick|Ultracentrifugation Exosomes 815 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes ts Cardiomyocyte cells - control Protein Western blotting 2013 Differential centrifugation|Filtration|ExoQuick|Ultracentrifugation Exosomes 816 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes ts Cardiomyocyte cells - exosomes exposed to 21.7 mM ethanol Protein Western blotting 2013 Differential centrifugation|Filtration|ExoQuick|Ultracentrifugation Exosomes 817 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes ts Cardiomyocyte cells - exosomes exposed to 65.1 mM ethanol Protein Western blotting 2013 Differential centrifugation|Filtration|ExoQuick|Ultracentrifugation Exosomes 818 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes ts Cardiomyocyte cells - exosomes at pH 6.6 Protein Western blotting 2013 Differential centrifugation|Filtration|ExoQuick|Ultracentrifugation Exosomes 819 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes ts Cardiomyocyte cells - exosomes at pH 7.1 Protein Western blotting 2013 Differential centrifugation|Filtration|ExoQuick|Ultracentrifugation Exosomes 820 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes ts Cardiomyocyte cells - exosomes at pH 7.4 Protein Western blotting 2013 Differential centrifugation|Filtration|ExoQuick|Ultracentrifugation Exosomes 821 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes ts Cardiomyocyte cells - exosomes incubated at 25°C Protein Western blotting 2013 Filtration|Ultracentrifugation|Sucrose and deuterium oxide density cushion Exosomes 822 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes ts Cardiomyocyte cells - exosomes incubated at 37°C Protein Western blotting 2013 Filtration|Ultracentrifugation|Sucrose density gradient Exosomes 823 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes ts Cardiomyocyte cells - exosomes incubated at 42°C Protein Western blotting 2013 Filtration|Ultracentrifugation|Sucrose density gradient Exosomes 824 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes ts Cardiomyocyte cells - exosomes at pH 7.1 - Rep 1 Protein Western blotting 2013 Filtration|Ultracentrifugation|Sucrose density gradient Exosomes 825 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes ts Cardiomyocyte cells - exosomes at pH 7.1 - Rep 2 Protein Western blotting 2013 Filtration|Ultracentrifugation|Sucrose density gradient Exosomes 826 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes ts Cardiomyocyte cells - exosomes at pH 7.4 - Rep 1 Protein Western blotting 2013 Filtration|Ultracentrifugation|Sucrose density gradient Exosomes 827 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes ts Cardiomyocyte cells - exosomes at pH 7.4 - Rep 2 Protein Western blotting 2013 Filtration|Ultracentrifugation|Sucrose density gradient Exosomes 828 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes ts Cardiomyocyte cells - control Protein Western blotting 2013 Filtration|Ultracentrifugation|Sucrose density gradient Exosomes 829 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes ts Cardiomyocyte cells - exosomes exposed to 21.7 mM ethanol Protein Western blotting 2013 Filtration|Ultracentrifugation|Sucrose density gradient Exosomes 830 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes ts Cardiomyocyte cells - exosomes exposed to 65.1 mM ethanol Protein Western blotting 2013 Filtration|Ultracentrifugation|Sucrose density gradient Exosomes 831 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes ts Cardiomyocyte cells - exosomes exposed to 65.1 mM ethanol - Rep 1 Protein Mass spectrometry|Western blotting 2013 Differential centrifugation|Filtration|ExoQuick|Ultracentrifugation Exosomes 832 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes ts Cardiomyocyte cells - exosomes exposed to 65.1 mM ethanol - Rep 2 Protein Mass spectrometry|Western blotting 2013 Differential centrifugation|Filtration|ExoQuick|Ultracentrifugation Exosomes 833 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes ts Cardiomyocyte cells - exosomes exposed to 65.1 mM ethanol - Rep 3 Protein Mass spectrometry|Western blotting 2013 Differential centrifugation|Filtration|ExoQuick|Ultracentrifugation Exosomes 834 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes ts Cardiomyocyte cells - exosomes exposed to 65.1 mM ethanol - Rep 4 Protein Western blotting 2013 Differential centrifugation|Filtration|ExoQuick|Ultracentrifugation Exosomes 835 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes ts Cardiomyocyte cells - mild hypoxia - Rep 1 Protein Mass spectrometry|Western blotting 2013 Differential centrifugation|Filtration|ExoQuick|Ultracentrifugation Exosomes 836 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes ts Cardiomyocyte cells - mild hypoxia - Rep 2 Protein Mass spectrometry|Western blotting 2013 Differential centrifugation|Filtration|ExoQuick|Ultracentrifugation Exosomes 837 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes ts Cardiomyocyte cells - mild hypoxia - Rep 3 Protein Mass spectrometry|Western blotting 2013 Differential centrifugation|Filtration|ExoQuick|Ultracentrifugation Exosomes 838 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes ts Cardiomyocyte cells - mild hypoxia - Rep 4 Protein Western blotting 2013 Differential centrifugation|Filtration|ExoQuick|Ultracentrifugation Exosomes 839 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Prostate cancer cells cl LNCaP Protein Western blotting 2016 Differential centrifugation|Ultracentrifugation Extracellular vesicles 840 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Prostate cancer cells cl LNCaP - in CSS Protein Western blotting 2016 Differential centrifugation|Ultracentrifugation Extracellular vesicles 841 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Prostate cancer cells cl LNCaP - in CSS - Rep 1 Protein Mass spectrometry 2016 Differential centrifugation|Ultracentrifugation Extracellular vesicles 842 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Prostate cancer cells cl LNCaP - in CSS - Rep 2 Protein Mass spectrometry 2016 Differential centrifugation|Ultracentrifugation Extracellular vesicles 843 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Prostate cancer cells cl LNCaP - in CSS - Rep 3 Protein Mass spectrometry 2016 Differential centrifugation|Ultracentrifugation Extracellular vesicles 844 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Prostate cancer cells cl LNCaP - in CSS with DHT treatment Protein Western blotting 2016 Differential centrifugation|Ultracentrifugation Extracellular vesicles 845 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Prostate cancer cells cl LNCaP - in CSS with DHT treatment - Rep 1 Protein Mass spectrometry 2016 Differential centrifugation|Ultracentrifugation Extracellular vesicles 846 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Prostate cancer cells cl LNCaP - in CSS with DHT treatment - Rep 2 Protein Mass spectrometry 2016 Differential centrifugation|Ultracentrifugation Extracellular vesicles 847 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Prostate cancer cells cl LNCaP - in CSS with DHT treatment - Rep 3 Protein Mass spectrometry 2016 Differential centrifugation|Ultracentrifugation Extracellular vesicles 848 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Prostate cancer cells cl LNCaP - in CSS with DHT and MDV3100 treatment Protein Western blotting 2016 Differential centrifugation|Ultracentrifugation Extracellular vesicles 849 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Prostate cancer cells cl DUCaP Protein Western blotting 2016 Differential centrifugation|Ultracentrifugation Extracellular vesicles 850 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Prostate cancer cells cl DUCaP - in CSS Protein Western blotting 2016 Differential centrifugation|Ultracentrifugation Extracellular vesicles 851 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Prostate cancer cells cl DUCaP - in CSS - Rep 1 Protein Mass spectrometry 2016 Differential centrifugation|Ultracentrifugation Extracellular vesicles 852 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Prostate cancer cells cl DUCaP - in CSS - Rep 2 Protein Mass spectrometry 2016 Differential centrifugation|Ultracentrifugation Extracellular vesicles 853 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Prostate cancer cells cl DUCaP - in CSS - Rep 3 Protein Mass spectrometry 2016 Differential centrifugation|Ultracentrifugation Extracellular vesicles 854 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Prostate cancer cells cl DUCaP - in CSS with DHT treatment Protein Western blotting 2016 Differential centrifugation|Ultracentrifugation Extracellular vesicles 855 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Prostate cancer cells cl DUCaP - in CSS with DHT treatment - Rep 1 Protein Mass spectrometry 2016 Differential centrifugation|Ultracentrifugation Extracellular vesicles 856 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Prostate cancer cells cl DUCaP - in CSS with DHT treatment - Rep 2 Protein Mass spectrometry 2016 Differential centrifugation|Ultracentrifugation Extracellular vesicles 857 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Prostate cancer cells cl DUCaP - in CSS with DHT treatment - Rep 3 Protein Mass spectrometry 2016 Differential centrifugation|Ultracentrifugation Extracellular vesicles 858 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Plasma ts Plasma - prostrate cancer patients Protein Time-resolved fluorescence immunoassay 2016 Differential centrifugation|Ultracentrifugation Extracellular vesicles 859 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Plasma ts Plasma - benign prostate hyperplasia patients Protein Time-resolved fluorescence immunoassay 2016 Differential centrifugation|Ultracentrifugation Extracellular vesicles 860 25776846 Homo sapiens Human thymic epithelial primary cells produce exosomes carrying tissue-restricted antigens Epithelial cells ts Thymic tissue Protein FACS 2015 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 861 25776846 Homo sapiens Human thymic epithelial primary cells produce exosomes carrying tissue-restricted antigens Epithelial cells ts Thymic tissue - culture 1 Protein Mass spectrometry 2015 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 862 25776846 Homo sapiens Human thymic epithelial primary cells produce exosomes carrying tissue-restricted antigens Epithelial cells ts Thymic tissue - culture 2 Protein Mass spectrometry 2015 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 863 22046311 Mus musculus Exosomes from Plasmodium yoelii-infected reticulocytes protect mice from lethal infections Plasma ts Peripheral blood plasma - P. yoelii 17X infected Protein FACS|Mass spectrometry 2011 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 864 22046311 Mus musculus Exosomes from Plasmodium yoelii-infected reticulocytes protect mice from lethal infections Plasma ts Peripheral blood plasma - P. yoelii 17X infected Protein FACS 2011 Differential centrifugation|Filtration|Sucrose density gradient|Ultracentrifugation Exosomes 865 22046311 Mus musculus Exosomes from Plasmodium yoelii-infected reticulocytes protect mice from lethal infections Reticulocytes ts Peripheral blood plasma - P. yoelii 17X infected Protein FACS 2011 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 866 24614226 Ovis aries Extracellular vesicles in luminal fluid of the ovine uterus Uterine luminal fluid ts Uterine luminal fluid - pregnant - Rep 1 Protein Western blotting 2014 Differential centrifugation|Filtration|ExoQuick Extracellular vesicles 867 24614226 Ovis aries Extracellular vesicles in luminal fluid of the ovine uterus Uterine luminal fluid ts Uterine luminal fluid - pregnant - Rep 2 Protein Western blotting 2014 Differential centrifugation|Filtration|ExoQuick Extracellular vesicles 868 24614226 Ovis aries Extracellular vesicles in luminal fluid of the ovine uterus Uterine luminal fluid ts Uterine luminal fluid - pregnant - Rep 3 Protein Western blotting 2014 Differential centrifugation|Filtration|ExoQuick Extracellular vesicles 869 24614226 Ovis aries Extracellular vesicles in luminal fluid of the ovine uterus Uterine luminal fluid ts Uterine luminal fluid - pregnant - n=4 pooled Protein Mass spectrometry 2014 Differential centrifugation|Filtration|ExoQuick Extracellular vesicles 870 24614226 Ovis aries Extracellular vesicles in luminal fluid of the ovine uterus Uterine luminal fluid ts Uterine luminal fluid - cyclic - Rep 1 Protein Western blotting 2014 Differential centrifugation|Filtration|ExoQuick Extracellular vesicles 871 24614226 Ovis aries Extracellular vesicles in luminal fluid of the ovine uterus Uterine luminal fluid ts Uterine luminal fluid - cyclic - Rep 2 Protein Western blotting 2014 Differential centrifugation|Filtration|ExoQuick Extracellular vesicles 872 24614226 Ovis aries Extracellular vesicles in luminal fluid of the ovine uterus Uterine luminal fluid ts Uterine luminal fluid - cyclic - Rep 3 Protein Western blotting 2014 Differential centrifugation|Filtration|ExoQuick Extracellular vesicles 873 24614226 Ovis aries Extracellular vesicles in luminal fluid of the ovine uterus Uterine luminal fluid ts Uterine luminal fluid - cyclic - n=4 pooled Protein Mass spectrometry 2014 Differential centrifugation|Filtration|ExoQuick Extracellular vesicles 874 24614226 Ovis aries Extracellular vesicles in luminal fluid of the ovine uterus Uterine luminal fluid ts Uterine luminal fluid - pregnant miRNA RNA sequencing 2014 Differential centrifugation|Filtration|ExoQuick Extracellular vesicles 875 24614226 Ovis aries Extracellular vesicles in luminal fluid of the ovine uterus Uterine luminal fluid ts Uterine luminal fluid - cyclic miRNA RNA sequencing 2014 Differential centrifugation|Filtration|ExoQuick Extracellular vesicles 876 29955024 Homo sapiens Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells Embryonic kidney cells cl HEK293T - control siRNA transfected Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 877 29955024 Homo sapiens Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells Embryonic kidney cells cl HEK293T - SphK1 siRNA transfected Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 878 29955024 Homo sapiens Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells Embryonic kidney cells cl HEK293T - SphK2 siRNA transfected Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 879 29955024 Homo sapiens Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells Myeloid leukemia cells cl K562 - control siRNA transfected Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 880 29955024 Homo sapiens Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells Myeloid leukemia cells cl K562 - co-transfected with SphK2 siRNA and empty vector Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 881 29955024 Homo sapiens Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells Myeloid leukemia cells cl K562 - co-transfected with SphK2 siRNA and siRNA-resistant WT SphK2 Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 882 29955024 Homo sapiens Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells Myeloid leukemia cells cl K562 - co-transfected with SphK2 siRNA and mutant SphK2 (G248D) Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 883 29955024 Homo sapiens Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells Myeloid leukemia cells cl K562 Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 884 29955024 Homo sapiens Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells Myeloid leukemia cells cl K562 - DMS treated Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 885 29955024 Homo sapiens Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells Myeloid leukemia cells cl K562 - HACPT treated Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 886 25102470 Homo sapiens Examination of the specificity of tumor cell derived exosomes with tumor cells in vitro Breast cancer cells cl MCF-7 Protein Mass spectrometry|Western blotting 2014 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 887 25102470 Homo sapiens Examination of the specificity of tumor cell derived exosomes with tumor cells in vitro Prostate cancer cells cl PC3 Protein Mass spectrometry 2014 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 888 24946052 Homo sapiens Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment Lung cancer cells cl PC9 Protein Western blotting 2014 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Extracellular vesicles 889 24946052 Homo sapiens Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment Lung cancer cells cl PC9 - Rep 1 Protein Mass spectrometry 2014 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Extracellular vesicles 890 24946052 Homo sapiens Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment Lung cancer cells cl PC9 - Rep 2 Protein Mass spectrometry 2014 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Extracellular vesicles 891 24946052 Homo sapiens Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment Lung cancer cells cl PC9 - Rep 3 Protein Mass spectrometry 2014 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Extracellular vesicles 892 24946052 Homo sapiens Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment Lung cancer cells cl PC9 - gefitinib-resistant Protein Western blotting 2014 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Extracellular vesicles 893 24946052 Homo sapiens Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment Lung cancer cells cl PC9 - gefitinib-resistant - Rep 1 Protein Mass spectrometry 2014 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Extracellular vesicles 894 24946052 Homo sapiens Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment Lung cancer cells cl PC9 - gefitinib-resistant - Rep 2 Protein Mass spectrometry 2014 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Extracellular vesicles 895 24946052 Homo sapiens Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment Lung cancer cells cl PC9 - gefitinib-resistant - Rep 3 Protein Mass spectrometry 2014 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Extracellular vesicles 896 26100252 Homo sapiens Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts Chronic lymphocytic leukemia cells ts CLL cells - Fraction 6 Protein Western blotting 2015 Differential centrifugation|Filtration|Ultracentrifugation|Density gradient centrifugation Exosomes 897 26100252 Homo sapiens Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts Chronic lymphocytic leukemia cells ts CLL cells - Fraction 7 Protein Western blotting 2015 Differential centrifugation|Filtration|Ultracentrifugation|Density gradient centrifugation Exosomes 898 26100252 Homo sapiens Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts Chronic lymphocytic leukemia cells ts CLL cells miRNA RNA sequencing 2015 Differential centrifugation|Filtration|Ultracentrifugation|Density gradient centrifugation Exosomes 899 26100252 Homo sapiens Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts Chronic lymphocytic leukemia cells ts CLL cells - Rep 1 Protein Mass spectrometry 2015 Differential centrifugation|Filtration|Ultracentrifugation|Density gradient centrifugation Exosomes 900 26100252 Homo sapiens Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts Chronic lymphocytic leukemia cells ts CLL cells - Rep 2 Protein Mass spectrometry 2015 Differential centrifugation|Filtration|Ultracentrifugation|Density gradient centrifugation Exosomes 901 26100252 Homo sapiens Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts Chronic lymphocytic leukemia cells cl JVM-3 Protein Mass spectrometry 2015 Differential centrifugation|Filtration|Ultracentrifugation|Density gradient centrifugation Exosomes 902 26100252 Homo sapiens Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts Chronic lymphocytic leukemia cells cl MEC-1 Protein Mass spectrometry|FACS|Western blotting 2015 Differential centrifugation|Filtration|Ultracentrifugation|Density gradient centrifugation Exosomes 903 25053844 Homo sapiens Activity-associated miRNA are packaged in Map1b-enriched exosomes released from depolarized neurons Neuroblastoma cells cl SH-SY5Y Protein Mass spectrometry|Western blotting 2014 Differential centrifugation|Ultracentrifugation|Filtration Exosomes 904 25053844 Homo sapiens Activity-associated miRNA are packaged in Map1b-enriched exosomes released from depolarized neurons Neuroblastoma cells cl SH-SY5Y miRNA Microarray 2014 Differential centrifugation|Ultracentrifugation|Filtration Exosomes 905 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer Bladder cancer cells cl TCCSUP Protein Mass spectrometry|Western blotting 2017 Differential centrifugation|Ultracentrifugation Extracellular vesicles 906 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer Urothelial cells cl SVHUC Protein Mass spectrometry 2017 Differential centrifugation|Ultracentrifugation Extracellular vesicles 907 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer Transitional papilloma cells cl RT4 Protein Western blotting 2017 Differential centrifugation|Ultracentrifugation Extracellular vesicles 908 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer Transitional carcinoma cells cl UMUC3 Protein Western blotting 2017 Differential centrifugation|Ultracentrifugation Extracellular vesicles 909 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer Transitional carcinoma cells cl T24 Protein Western blotting 2017 Differential centrifugation|Ultracentrifugation Extracellular vesicles 910 28687758 Sus scrofa Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers Polarised retinal pigmented epithelial cells ts Polarised RPE cells - apical - Fraction 6 Protein Western blotting 2017 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 911 28687758 Sus scrofa Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers Polarised retinal pigmented epithelial cells ts Polarised RPE cells - apical - Fraction 7 Protein Western blotting 2017 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 912 28687758 Sus scrofa Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers Polarised retinal pigmented epithelial cells ts Polarised RPE cells - apical - Fraction 8 Protein Western blotting 2017 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 913 28687758 Sus scrofa Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers Polarised retinal pigmented epithelial cells ts Polarised RPE cells - basolateral - Fraction 6 Protein Western blotting 2017 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 914 28687758 Sus scrofa Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers Polarised retinal pigmented epithelial cells ts Polarised RPE cells - basolateral - Fraction 7 Protein Western blotting 2017 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 915 28687758 Sus scrofa Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers Polarised retinal pigmented epithelial cells ts Polarised RPE cells - basolateral - Fraction 8 Protein Western blotting 2017 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 916 28687758 Sus scrofa Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers Polarised retinal pigmented epithelial cells ts Polarised RPE cells - apical - Rep 1 Protein Mass spectrometry 2017 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 917 28687758 Sus scrofa Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers Polarised retinal pigmented epithelial cells ts Polarised RPE cells - apical - Rep 2 Protein Mass spectrometry 2017 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 918 28687758 Sus scrofa Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers Polarised retinal pigmented epithelial cells ts Polarised RPE cells - basolateral - Rep 1 Protein Mass spectrometry 2017 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 919 28687758 Sus scrofa Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers Polarised retinal pigmented epithelial cells ts Polarised RPE cells - basolateral - Rep 2 Protein Mass spectrometry 2017 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 920 28687758 Sus scrofa Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers Polarised retinal pigmented epithelial cells ts Polarised RPE cells - apical - Fraction 9 Protein Mass spectrometry 2017 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Extracellular vesicles 921 28687758 Sus scrofa Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers Polarised retinal pigmented epithelial cells ts Polarised RPE cells - basolateral - Fraction 9 Protein Mass spectrometry 2017 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Extracellular vesicles 922 25483805 Homo sapiens Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties Embryonic kidney cells cl HEK293T - P150 Protein Western blotting|Immunofluorescence 2014 Differential centrifugation|Ultracentrifugation Exosomes 923 25483805 Homo sapiens Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties Embryonic kidney cells cl HEK293T - P450 Protein Western blotting|Immunofluorescence 2014 Differential centrifugation|Ultracentrifugation Exosomes 924 25483805 Homo sapiens Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties Embryonic kidney cells cl HEK293T - P150 - Fraction 1.09 g/mL Protein Western blotting 2014 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 925 25483805 Homo sapiens Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties Embryonic kidney cells cl HEK293T - P150 - Fraction 1.12 g/mL Protein Mass spectrometry|Western blotting 2014 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 926 25483805 Homo sapiens Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties Embryonic kidney cells cl HEK293T - P450 - Fraction 1.09 g/mL Protein Western blotting 2014 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 927 25483805 Homo sapiens Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties Embryonic kidney cells cl HEK293T - P450 - Fraction 1.12 g/mL Protein Mass spectrometry|Western blotting 2014 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 928 25483805 Gallus gallus Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties Notochord cells cl Notochord cells - P150 Protein Western blotting 2014 Differential centrifugation|Ultracentrifugation Exosomes 929 25483805 Gallus gallus Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties Notochord cells cl Notochord cells - P450 Protein Western blotting 2014 Differential centrifugation|Ultracentrifugation Exosomes 930 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. Bladder cancer cells cl TCCSUP Protein Mass spectrometry|Western blotting 2017 Differential centrifugation|Ultracentrifugation Extracellular vesicles 931 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. Urothelial cells cl SVHUC Protein Mass spectrometry 2017 Differential centrifugation|Ultracentrifugation Extracellular vesicles 932 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. Bladder cancer cells cl RT4 Protein Western blotting 2017 Differential centrifugation|Ultracentrifugation Extracellular vesicles 933 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. Bladder cancer cells cl UMUC3 Protein Western blotting 2017 Differential centrifugation|Ultracentrifugation Extracellular vesicles 934 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. Bladder cancer cells cl T24 Protein Western blotting 2017 Differential centrifugation|Ultracentrifugation Extracellular vesicles 935 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. Urine ts Urine - healthy volenteer 1 Protein Western blotting 2017 Differential centrifugation|Ultracentrifugation Extracellular vesicles 936 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. Urine ts Urine - healthy volenteer 2 Protein Western blotting 2017 Differential centrifugation|Ultracentrifugation Extracellular vesicles 937 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. Urine ts Urine - healthy volenteer 3 Protein Western blotting 2017 Differential centrifugation|Ultracentrifugation Extracellular vesicles 938 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. Urine ts Urine - healthy volenteer 4 Protein Western blotting 2017 Differential centrifugation|Ultracentrifugation Extracellular vesicles 939 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. Urine ts Urine - healthy volenteer 5 Protein Western blotting 2017 Differential centrifugation|Ultracentrifugation Extracellular vesicles 940 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. Urine ts Urine - healthy volenteer 6 Protein Western blotting 2017 Differential centrifugation|Ultracentrifugation Extracellular vesicles 941 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. Urine ts Urine - bladder cancer patient 1 (Stage pT3a) Protein Western blotting 2017 Differential centrifugation|Ultracentrifugation Extracellular vesicles 942 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. Urine ts Urine - bladder cancer patient 2 (Stage pT3a) Protein Western blotting 2017 Differential centrifugation|Ultracentrifugation Extracellular vesicles 943 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. Urine ts Urine - bladder cancer patient 3 (Stage pT2b) Protein Western blotting 2017 Differential centrifugation|Ultracentrifugation Extracellular vesicles 944 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. Urine ts Urine - bladder cancer patient 4 (Stage pT2a) Protein Western blotting 2017 Differential centrifugation|Ultracentrifugation Extracellular vesicles 945 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. Urine ts Urine - bladder cancer patient 5 (Stage pT1) Protein Western blotting 2017 Differential centrifugation|Ultracentrifugation Extracellular vesicles 946 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. Urine ts Urine - bladder cancer patient 6 (Stage pT1) Protein Western blotting 2017 Differential centrifugation|Ultracentrifugation Extracellular vesicles 947 28819550 Mus musculus Effects of storage temperature on airway exosome integrity for diagnostic and functional analyses. Bronchoalveolar lavage fluid ts Bronchoalveolar lavage (BAL) fluid - Fresh Protein Mass spectrometry|Western blotting 2017 Differential centrifugation|Ultracentrifugation Exosomes 948 28819550 Mus musculus Effects of storage temperature on airway exosome integrity for diagnostic and functional analyses. Bronchoalveolar lavage fluid ts Bronchoalveolar lavage (BAL) fluid - 4C Protein Mass spectrometry|Western blotting 2017 Differential centrifugation|Ultracentrifugation Exosomes 949 28819550 Mus musculus Effects of storage temperature on airway exosome integrity for diagnostic and functional analyses. Bronchoalveolar lavage fluid ts Bronchoalveolar lavage (BAL) fluid - -80C Protein Mass spectrometry|Western blotting 2017 Differential centrifugation|Ultracentrifugation Exosomes 950 27601599 Homo sapiens Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. Breast milk ts Milk - derived EVs - D1 Protein Mass spectrometry 2016 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Extracellular vesicles 951 27601599 Homo sapiens Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. Breast milk ts Milk - derived EVs - D2 Protein Mass spectrometry 2016 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Extracellular vesicles 952 27601599 Homo sapiens Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. Breast milk ts Milk - derived EVs - D3 Protein Mass spectrometry 2016 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Extracellular vesicles 953 27601599 Homo sapiens Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. Breast milk ts Milk - derived EVs - D4 Protein Mass spectrometry|Western blotting 2016 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Extracellular vesicles 954 27601599 Homo sapiens Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. Breast milk ts Milk - derived EVs - D5 Protein Mass spectrometry|Western blotting 2016 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Extracellular vesicles 955 27601599 Homo sapiens Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. Breast milk ts Milk - derived EVs - D6 Protein Mass spectrometry|Western blotting 2016 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Extracellular vesicles 956 27601599 Homo sapiens Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. Breast milk ts Milk - derived EVs - D7 Protein Mass spectrometry|Western blotting 2016 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Extracellular vesicles 957 27601599 Homo sapiens Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. Breast milk ts Milk - derived EVs - pooled Protein Mass spectrometry 2016 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Extracellular vesicles 958 26196085 Homo sapiens Identification of prostate cancer biomarkers in urinary exosomes. Urine ts Urine - prostate cancer control Protein Mass spectrometry|Western blotting 2015 Differential centrifugation|Ultracentrifugation|Filtration Exosomes 959 26196085 Homo sapiens Identification of prostate cancer biomarkers in urinary exosomes. Urine ts Urine - prostate cancer patients Protein Mass spectrometry|Western blotting 2015 Differential centrifugation|Ultracentrifugation|Filtration Exosomes 960 26047123 Bos taurus Oral administration of bovine milk derived extracellular vesicles attenuates arthritis in two mouse models. Bovine milk ts Bovine milk Protein Mass spectrometry 2015 Differential centrifugation|Ultracentrifugation|Filtration Extracellular vesicles 961 26047123 Bos taurus Oral administration of bovine milk derived extracellular vesicles attenuates arthritis in two mouse models. Bovine milk ts Bovine milk miRNA RT-PCR 2015 Differential centrifugation|Ultracentrifugation|Filtration Extracellular vesicles 962 26047123 Bos taurus Oral administration of bovine milk derived extracellular vesicles attenuates arthritis in two mouse models. Bovine milk ts Bovine milk mRNA RT-PCR 2015 Differential centrifugation|Ultracentrifugation|Filtration Extracellular vesicles 963 25844599 Homo sapiens Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. Prostate cancer cells cl DU145 Tax-Sen Protein Mass spectrometry|Western blotting 2015 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 964 25844599 Homo sapiens Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. Prostate cancer cells cl DU145 Tax-Res Protein Mass spectrometry|Western blotting 2015 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 965 25844599 Homo sapiens Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. Serum ts castration resistant prostate cancer patient - R1 Protein Western blotting 2015 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 966 25844599 Homo sapiens Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. Serum ts castration resistant prostate cancer patient - R2 Protein Western blotting 2015 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 967 25844599 Homo sapiens Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. Serum ts castration resistant prostate cancer patient - R3 Protein Western blotting 2015 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 968 25844599 Homo sapiens Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. Serum ts castration resistant prostate cancer patient - S4 Protein Western blotting 2015 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 969 25844599 Homo sapiens Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. Serum ts castration resistant prostate cancer patient - S5 Protein Western blotting 2015 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 970 25844599 Homo sapiens Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. Serum ts castration resistant prostate cancer patient - S6 Protein Western blotting 2015 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 971 22808001 Homo sapiens Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment. Serum ts Serum -Tuberculosis patient 1 Protein Mass spectrometry 2012 Filtration|ExoQuick Exosomes 972 22808001 Homo sapiens Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment. Serum ts Serum -Tuberculosis patient 2 Protein Mass spectrometry 2012 Filtration|ExoQuick Exosomes 973 22808001 Homo sapiens Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment. Serum ts Serum -Tuberculosis patient 3 Protein Mass spectrometry 2012 Filtration|ExoQuick Exosomes 974 22808001 Homo sapiens Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment. Serum ts Serum -Tuberculosis patient 4 Protein Mass spectrometry 2012 Filtration|ExoQuick Exosomes 975 22808001 Homo sapiens Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment. Serum ts Serum -Tuberculosis patient 5 Protein Mass spectrometry 2012 Filtration|ExoQuick Exosomes 976 22808001 Homo sapiens Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment. Serum ts Serum -Tuberculosis patient 6 Protein Mass spectrometry 2012 Filtration|ExoQuick Exosomes 977 22808001 Homo sapiens Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment. Serum ts Serum -Tuberculosis patient 7 Protein Mass spectrometry 2012 Filtration|ExoQuick Exosomes 978 22808001 Homo sapiens Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment. Serum ts Serum -Tuberculosis patient 8 Protein Mass spectrometry 2012 Filtration|ExoQuick Exosomes 979 25471885 Drosophila melanogaster The ESCRT machinery regulates the secretion and long-range activity of Hedgehog. Drosophila wing imaginal Disc cl C18 Protein Mass spectrometry|Western blotting 2014 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Extracellular vesicles 980 25471885 Drosophila melanogaster The ESCRT machinery regulates the secretion and long-range activity of Hedgehog. Drosophila wing imaginal Disc cl C18 Protein Western blotting 2014 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Extracellular vesicles 981 25458527 Homo sapiens Benchtop isolation and characterization of functional exosomes by sequential filtration Breast cancer cells cl MDA231 Protein Mass spectrometry|Dot blot 2014 Sequential filtration Exosomes 982 25458527 Homo sapiens Benchtop isolation and characterization of functional exosomes by sequential filtration Breast cancer cells cl MDA231 Protein Mass spectrometry|Dot blot 2014 Differential centrifugation|Ultracentrifugation Exosomes 983 25367658 Candida albicans Proteomics unravels extracellular vesicles as carriers of classical cytoplasmic proteins in Candida albicans. Candida albicans cl Candida albicans - SC5314 Protein Mass spectrometry|Western blotting 2015 Differential centrifugation|Ultracentrifugation|Filtration Extracellular vesicles 984 25287304 Candida albicans Compositional and immunobiological analyses of extracellular vesicles released by Candida albicans. Candida albicans cl Candida albicans - Strain 11 Protein Mass spectrometry 2015 Differential centrifugation|Ultracentrifugation Extracellular vesicles 985 25287304 Candida albicans Compositional and immunobiological analyses of extracellular vesicles released by Candida albicans. Candida albicans cl Candida albicans - ATCC 90028 Protein Mass spectrometry 2015 Differential centrifugation|Ultracentrifugation Extracellular vesicles 986 25261472 Homo sapiens Complex N-linked glycans serve as a determinant for exosome/microvesicle cargo recruitment. Melanoma cells cl SK-MEL-5 Protein Mass spectrometry|Western blotting 2014 Differential centrifugation|Ultracentrifugation Exosomes/Microvesicles 987 25261472 Homo sapiens Complex N-linked glycans serve as a determinant for exosome/microvesicle cargo recruitment. Melanoma cells cl SK-MEL-5 - DMJ treated Protein Western blotting 2014 Differential centrifugation|Ultracentrifugation Exosomes/Microvesicles 988 25261472 Homo sapiens Complex N-linked glycans serve as a determinant for exosome/microvesicle cargo recruitment. Melanoma cells cl SK-MEL-5 -mutant EW1-2 (N1) Protein Western blotting 2014 Differential centrifugation|Ultracentrifugation Exosomes/Microvesicles 989 25261472 Homo sapiens Complex N-linked glycans serve as a determinant for exosome/microvesicle cargo recruitment. Melanoma cells cl SK-MEL-5 -mutant EW1-2 (N12) Protein Western blotting 2014 Differential centrifugation|Ultracentrifugation Exosomes/Microvesicles 990 25261472 Homo sapiens Complex N-linked glycans serve as a determinant for exosome/microvesicle cargo recruitment. Melanoma cells cl SK-MEL-5 -mutant EW1-2 (N123) Protein Western blotting 2014 Differential centrifugation|Ultracentrifugation Exosomes/Microvesicles 991 25138791 Homo sapiens The exocyst and regulatory GTPases in urinary exosomes. Urine ts Urine - normal volunteer Protein Mass spectrometry 2014 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Extracellular vesicles 992 24434149 Homo sapiens In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. Ovarian cancer cells cl OVCAR3 Protein Mass spectrometry|Western blotting 2014 Differential centrifugation|Ultracentrifugation Exosomes 993 24434149 Homo sapiens In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. Ovarian cancer cells cl OVCAR433 Protein Mass spectrometry|Western blotting 2014 Differential centrifugation|Ultracentrifugation Exosomes 994 24434149 Homo sapiens In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. Ovarian cancer cells cl OVCAR5 Protein Mass spectrometry|Western blotting 2014 Differential centrifugation|Ultracentrifugation Exosomes 995 24434149 Homo sapiens In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. Ovarian cancer cells cl SKOV3 Protein Mass spectrometry|Western blotting 2014 Differential centrifugation|Ultracentrifugation Exosomes 996 24392111 Mus musculus Proteomic analysis of C2C12 myoblast and myotube exosome-like vesicles: a new paradigm for myoblast-myotube cross talk? Murine myoblast cl C2C12 - MB Protein Mass spectrometry|Western blotting 2014 Differential centrifugation|Ultracentrifugation Extracellular vesicles 997 24392111 Mus musculus Proteomic analysis of C2C12 myoblast and myotube exosome-like vesicles: a new paradigm for myoblast-myotube cross talk? Murine myotubues cl C2C12 - MT Protein Mass spectrometry|Western blotting 2014 Differential centrifugation|Ultracentrifugation Extracellular vesicles 998 24355714 Homo sapiens Proteomic analysis and immune properties of exosomes released by macrophages infected with Mycobacterium avium. Leukemia cells cl THP-1 (macrophage-like) Protein Mass spectrometry|FACS|ELISA 2014 Differential centrifugation|Ultracentrifugation Exosomes 999 24355714 Homo sapiens Proteomic analysis and immune properties of exosomes released by macrophages infected with Mycobacterium avium. Leukemia cells cl THP-1 (macrophage-like) - infected with Mycobacterium avium sp. paratuberculosis Protein Mass spectrometry|FACS|ELISA 2014 Differential centrifugation|Ultracentrifugation Exosomes 1000 24079734 Mus musculus Immunostimulatory activity of murine keratinocyte-derived exosomes. Keratinocytes cl MPEK-BL6 Protein Mass spectrometry|Western blotting 2013 Differential centrifugation|Ultracentrifugation Exosomes 1001 24079734 Mus musculus Immunostimulatory activity of murine keratinocyte-derived exosomes. Keratinocytes cl MPEK-BL6 - treated with IFN-. Protein Mass spectrometry|Western blotting 2013 Differential centrifugation|Ultracentrifugation Exosomes 1002 24211404 Mus musculus Induction of pulmonary hypertensive changes by extracellular vesicles from monocrotaline-treated mice. Lung tissue ts Lung tissue Protein Mass spectrometry 2013 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1003 23785420 Bos taurus CD9-positive microvesicles mediate the transfer of molecules to Bovine Spermatozoa during epididymal maturation. Epididymal fluid ts Epididymal fluids Protein Mass spectrometry|Western blotting 2013 Differential centrifugation|Ultracentrifugation|Immunoaffinity [CD9] Microvesicles 1004 23463506 Homo sapiens The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes. T cells cl T lymphoblasts - exosomes pulldown with CD81 as a bait Protein Mass spectrometry|Western blotting 2013 Differential centrifugation|Ultracentrifugation Exosomes 1005 23463506 Homo sapiens The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes. T cells cl T lymphoblasts - exosomes pulldown with EWI-2 as a bait Protein Mass spectrometry|Western blotting 2013 Differential centrifugation|Ultracentrifugation Exosomes 1006 23463506 Mus musculus The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes. T cells cl T lymphoblasts - WT mice Protein Western blotting 2013 Differential centrifugation|Ultracentrifugation Exosomes 1007 23463506 Mus musculus The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes. T cells cl T lymphoblasts - CD81 KO mice Protein Mass spectrometry|Western blotting 2013 Differential centrifugation|Ultracentrifugation Exosomes 1008 23463506 Homo sapiens The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes. T cells cl T lymphoblasts Protein Mass spectrometry 2013 Differential centrifugation|Ultracentrifugation Exosomes 1009 23185418 Homo sapiens Improved flow cytometric assessment reveals distinct microvesicle (cell-derived microparticle) signatures in joint diseases. Synovial fluid ts synovial fluid - patient with osteoarthritis (OA) Protein Mass spectrometry|FACS 2012 Filtration|Ultracentrifugation Microvesicles 1010 23185418 Homo sapiens Improved flow cytometric assessment reveals distinct microvesicle (cell-derived microparticle) signatures in joint diseases. Synovial fluid ts synovial fluid - patient with rheumatoid arthritis (RA) Protein Mass spectrometry|FACS 2012 Filtration|Ultracentrifugation Microvesicles 1011 23185418 Homo sapiens Improved flow cytometric assessment reveals distinct microvesicle (cell-derived microparticle) signatures in joint diseases. Synovial fluid ts synovial fluid - patient with juvenile idiopathic arthritis (JIA) Protein Mass spectrometry|FACS 2012 Filtration|Ultracentrifugation Microvesicles 1012 22711894 Homo sapiens Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages. Macrophage cl Monocyte-derived macrophages - uninfected Protein Mass spectrometry 2012 Differential centrifugation|Filtration|Ultracentrifugation Microvesicles/Exosomes 1013 22711894 Homo sapiens Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages. Macrophage cl Monocyte-derived macrophages - HLA-DR pulldwon microvesicles Protein |Lipids Mass spectrometry 2012 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1014 22711894 Homo sapiens Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages. Macrophage cl Monocyte-derived macrophages - CHMP4/TSG101 pulldown exosomes Protein |Lipids Mass spectrometry 2012 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1015 22711894 Homo sapiens Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages. Macrophage cl Monocyte-derived macrophages - Myosin B pulldown exosomes Protein |Lipids Mass spectrometry 2012 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1016 22711894 Homo sapiens Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages. Macrophage cl Monocyte-derived macrophages - Rab 11 Protein |Lipids Mass spectrometry 2012 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1017 22711894 Homo sapiens Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages. Macrophage cl Monocyte-derived macrophages - Vinculin/Talin pulldown exosomes Protein |Lipids Mass spectrometry 2012 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1018 22399603 Homo sapiens Proteomic analysis of exosome-like vesicles derived from breast cancer cells. Breast cancer cells cl MDA-MB-231 Protein Mass spectrometry|Western blotting 2012 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1019 21734072 Mus musculus Insulinoma-released exosomes or microparticles are immunostimulatory and can activate autoreactive T cells spontaneously developed in nonobese diabetic mice. Insulinoma cells cl MIN6 Protein Mass spectrometry|Western blotting 2011 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1020 21734072 Mus musculus Insulinoma-released exosomes or microparticles are immunostimulatory and can activate autoreactive T cells spontaneously developed in nonobese diabetic mice. Insulinoma cells cl NIT-1 Protein Western blotting 2011 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1021 20332430 Homo sapiens Proteomic analysis of prostate cancer metastasis-derived prostasomes. Skeletal tissue ts Skeletal metastases - prostate cancer Protein Mass spectrometry 2010 Differential centrifugation|Ultracentrifugation Prostasomes 1022 19665478 Salmo salar CpG-induced secretion of MHCIIbeta and exosomes from salmon (Salmo salar) APCs. Head kidney leukocytes cl Head kidney leukocytes - CpG stimulated Protein Mass spectrometry 2010 Differential centrifugation|Ultracentrifugation Exosomes 1023 22327366 Homo sapiens Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs. Vascular endothelial cells cl HUVECS - mock - rep1 Protein Mass spectrometry 2012 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1024 22327366 Homo sapiens Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs. Vascular endothelial cells cl HUVECS - mock - rep2 Protein Mass spectrometry 2012 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1025 22327366 Homo sapiens Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs. Vascular endothelial cells cl HUVECS - KLF2-transduced -rep1 Protein |miRNA Mass spectrometry|RT-PCR 2012 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1026 22327366 Homo sapiens Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs. Vascular endothelial cells cl HUVECS - KLF2-transduced -rep2 Protein Mass spectrometry 2012 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1027 24211404 Homo sapiens Diabetic nephropathy induces changes in the proteome of human urinary exosomes as revealed by label-free comparative analysis. Urine ts Urine - Diabetic nephropathy (DN) patients Protein Mass spectrometry|Western blotting 2014 Ultracentrifugation|ExoQuick Exosomes 1028 26378940 Homo sapiens Redefining the Breast Cancer Exosome Proteome by Tandem Mass Tag Quantitative Proteomics and Multivariate Cluster Analysis. Breast cancer cells cl SKBR3B - 10 K pellet Protein Mass spectrometry|Western blotting 2015 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1029 26378940 Homo sapiens Redefining the Breast Cancer Exosome Proteome by Tandem Mass Tag Quantitative Proteomics and Multivariate Cluster Analysis. Breast cancer cells cl SKBR3B - 100 K pellet Protein Mass spectrometry|Western blotting 2015 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1030 26378940 Homo sapiens Redefining the Breast Cancer Exosome Proteome by Tandem Mass Tag Quantitative Proteomics and Multivariate Cluster Analysis. Breast cancer cells cl SKBR3B - Opti pellet Protein Mass spectrometry|Western blotting 2015 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Extracellular vesicles 1031 29887978 Homo sapiens Evaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing. Serum ts Serum - Volunteer (ExoRNeasy) Protein|miRNA Western blotting|Next generation sequencing 2018 exoEasy columns Extracellular vesicles 1032 29887978 Homo sapiens Evaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing. Serum ts Serum - Sepsis patient (ExoRNeasy) Protein|miRNA Western blotting|Next generation sequencing 2018 exoEasy columns Extracellular vesicles 1033 29887978 Homo sapiens Evaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing. Serum ts Serum - Volunteer (qEV) Protein|miRNA Western blotting|Next generation sequencing 2018 qEV size-exclusion column Extracellular vesicles 1034 29887978 Homo sapiens Evaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing. Serum ts Serum - Sepsis patient (qEV) Protein|miRNA Western blotting|Next generation sequencing 2018 qEV size-exclusion column Extracellular vesicles 1035 29887978 Homo sapiens Evaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing. Serum ts Serum - Volunteer (Exo-spin) Protein|miRNA Western blotting|Next generation sequencing 2018 Exo-spin Extracellular vesicles 1036 29887978 Homo sapiens Evaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing. Serum ts Serum - Sepsis patient (Exo-spin) Protein|miRNA Western blotting|Next generation sequencing 2018 Exo-spin Extracellular vesicles 1037 29887978 Homo sapiens Evaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing. Serum ts Serum - Volunteer (miRCURY) Protein|miRNA Western blotting|Next generation sequencing 2018 miRCURY Exosome Isolation Kit Extracellular vesicles 1038 29887978 Homo sapiens Evaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing. Serum ts Serum - Sepsis patient (miRCURY) Protein|miRNA Western blotting|Next generation sequencing 2018 miRCURY Exosome Isolation Kit Extracellular vesicles 1039 27770278 Homo sapiens Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease. Glioblastoma cells cl A172 Protein Mass spectrometry 2017 Differential centrifugation|Ultracentrifugation|Filtration|Density gradient centrifugation Extracellular vesicles 1040 27770278 Homo sapiens Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease. Glioblastoma cells cl LN229 Protein Mass spectrometry|Western blotting 2017 Differential centrifugation|Ultracentrifugation|Filtration|Density gradient centrifugation Extracellular vesicles 1041 27770278 Homo sapiens Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease. Glioblastoma cells cl U87MG Protein Mass spectrometry|Western blotting 2017 Differential centrifugation|Ultracentrifugation|Filtration|Density gradient centrifugation Extracellular vesicles 1042 27770278 Homo sapiens Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease. Glioblastoma cells cl U251 Protein Mass spectrometry 2017 Differential centrifugation|Ultracentrifugation|Filtration|Density gradient centrifugation Extracellular vesicles 1043 27770278 Homo sapiens Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease. Glioblastoma cells cl T98G Protein Mass spectrometry 2017 Differential centrifugation|Ultracentrifugation|Filtration|Density gradient centrifugation Extracellular vesicles 1044 27770278 Homo sapiens Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease. Glioblastoma cells cl CCF-STTG1 Protein Mass spectrometry 2017 Differential centrifugation|Ultracentrifugation|Filtration|Density gradient centrifugation Extracellular vesicles 1045 28725021 Bos taurus Bovine milk-derived exosomes from colostrum are enriched with proteins implicated in immune response and growth. Bovine milk ts Bovine milk - colostrum 12 h and 24 h Protein Mass spectrometry|Western blotting 2017 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 1046 28725021 Bos taurus Bovine milk-derived exosomes from colostrum are enriched with proteins implicated in immune response and growth. Bovine milk ts Bovine milk - colostrum 72 h Protein Mass spectrometry|Western blotting 2017 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 1047 28725021 Bos taurus Bovine milk-derived exosomes from colostrum are enriched with proteins implicated in immune response and growth. Bovine milk ts Bovine milk - colostrum 48 h Protein Mass spectrometry|Western blotting 2017 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 1048 28725021 Bos taurus Bovine milk-derived exosomes from colostrum are enriched with proteins implicated in immune response and growth. Bovine milk ts Bovine milk - mature milk Protein Mass spectrometry|Western blotting 2017 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 1049 28842968 Homo sapiens Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles. Colorectal cancer cells cl LIM1215 - NI Protein Mass spectrometry|Western blotting 2017 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1050 28842968 Homo sapiens Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles. Colorectal cancer cells cl lim1215 - II Protein Mass spectrometry|Western blotting 2017 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1051 29115712 Mus musculus Proteomic Profiling of Exosomes Secreted by Breast Cancer Cells with Varying Metastatic Potential. Breast cancer cells cl 67NR Protein Mass spectrometry|Western blotting 2017 Differential centrifugation|Ultracentrifugation Exosomes 1052 29115712 Mus musculus Proteomic Profiling of Exosomes Secreted by Breast Cancer Cells with Varying Metastatic Potential. Breast cancer cells cl 66cl4 Protein Mass spectrometry|Western blotting 2017 Differential centrifugation|Ultracentrifugation Exosomes 1053 29115712 Mus musculus Proteomic Profiling of Exosomes Secreted by Breast Cancer Cells with Varying Metastatic Potential. Breast cancer cells cl 4T1 Protein Mass spectrometry|Western blotting 2017 Differential centrifugation|Ultracentrifugation Exosomes 1054 29115712 Mus musculus Proteomic Profiling of Exosomes Secreted by Breast Cancer Cells with Varying Metastatic Potential. Breast cancer cells cl 4T1.2 Protein Mass spectrometry|Western blotting 2017 Differential centrifugation|Ultracentrifugation Exosomes 1055 30035390 Mus musculus Arrestin-domain Containing Protein 1 (Arrdc1) Regulates the Protein Cargo and Release of Extracellular Vesicles. Mouse embryonic fibroblasts cl MEFs - WT 10K Protein Mass spectrometry|Western blotting 2018 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1056 30035390 Mus musculus Arrestin-domain Containing Protein 1 (Arrdc1) Regulates the Protein Cargo and Release of Extracellular Vesicles. Mouse embryonic fibroblasts cl MEFs - WT exosomes Protein Mass spectrometry|Western blotting 2018 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1057 30035390 Mus musculus Arrestin-domain Containing Protein 1 (Arrdc1) Regulates the Protein Cargo and Release of Extracellular Vesicles. Mouse embryonic fibroblasts cl MEFs - Arrdc1 KO 10K Protein Mass spectrometry|Western blotting 2018 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1058 30035390 Mus musculus Arrestin-domain Containing Protein 1 (Arrdc1) Regulates the Protein Cargo and Release of Extracellular Vesicles. Mouse embryonic fibroblasts cl MEFs - Arrdc1 KO exosomes Protein Mass spectrometry|Western blotting 2018 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1059 30006486 Homo sapiens The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells. Astrocytoma cells cl U373 - EVs 1 Protein Mass spectrometry|Western blotting 2018 Filtration|Ultracentrifugation|Density gradient centrifugation Extracellular vesicles 1060 30006486 Homo sapiens The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells. Astrocytoma cells cl U373 - EVs 2 Protein Mass spectrometry 2018 Filtration|Ultracentrifugation|Density gradient centrifugation Extracellular vesicles 1061 30006486 Homo sapiens The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells. Astrocytoma cells cl U373 - EVs 3 Protein Mass spectrometry 2018 Filtration|Ultracentrifugation|Density gradient centrifugation Extracellular vesicles 1062 30006486 Homo sapiens The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells. Astrocytoma cells cl U373vIII - EVs 1 Protein Mass spectrometry|Western blotting 2018 Filtration|Ultracentrifugation|Density gradient centrifugation Extracellular vesicles 1063 30006486 Homo sapiens The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells. Astrocytoma cells cl U373vIII - EVs 2 Protein Mass spectrometry 2018 Filtration|Ultracentrifugation|Density gradient centrifugation Extracellular vesicles 1064 30006486 Homo sapiens The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells. Astrocytoma cells cl U373vIII - EVs 3 Protein Mass spectrometry 2018 Filtration|Ultracentrifugation|Density gradient centrifugation Extracellular vesicles 1065 29963299 Homo sapiens Enrichment of extracellular vesicles from human synovial fluid using size exclusion chromatography. Synovial fluid ts synovial fluid - EVs Proteinase K treated Protein Mass spectrometry|Western blotting 2018 Size exclusion chromatography Extracellular vesicles 1066 29963299 Homo sapiens Enrichment of extracellular vesicles from human synovial fluid using size exclusion chromatography. Synovial fluid ts synovial fluid - EVs untreated Protein Mass spectrometry|Western blotting 2018 Size exclusion chromatography Extracellular vesicles 1067 29937354 Homo sapiens Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors. Glioblastoma cells cl Untreated GBM157 - MVs Protein Mass spectrometry|Western blotting 2018 Differential centrifugation|Filtration Microvesicles 1068 29937354 Homo sapiens Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors. Glioblastoma cells cl Lethally irradiated GBM157 -MVs (apoMVs) Protein Mass spectrometry|Western blotting 2018 Differential centrifugation|Filtration Microvesicles 1069 29937354 Homo sapiens Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors. Glioblastoma cells cl Untreated GBM157 - Exo - Biorep1 Protein Mass spectrometry|Western blotting 2018 Differential centrifugation|Ultracentrifugation Exosomes 1070 29937354 Homo sapiens Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors. Glioblastoma cells cl Untreated GBM157 - Exo - Biorep2 Protein Mass spectrometry 2018 Differential centrifugation|Ultracentrifugation Exosomes 1071 29937354 Homo sapiens Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors. Glioblastoma cells cl Lethally irradiated GBM157 - apoExo - biorep1 Protein Mass spectrometry|Western blotting 2018 Differential centrifugation|Ultracentrifugation Exosomes 1072 29937354 Homo sapiens Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors. Glioblastoma cells cl Lethally irradiated GBM157 - apoExo - biorep2 Protein Mass spectrometry 2018 Differential centrifugation|Ultracentrifugation Exosomes 1073 25104112 Homo sapiens Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. Plasma ts Fresh plasma- healthy women Protein Western blotting 2014 Differential centrifugation|Ultracentrifugation|Filtration|Density gradient centrifugation Exosomes 1074 25104112 Homo sapiens Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. Plasma ts Stored plasma(freeze/thaw) plasma- healthy women Protein Western blotting 2014 Differential centrifugation|Ultracentrifugation|Filtration|Density gradient centrifugation Exosomes 1075 25104112 Homo sapiens Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. Plasma ts Fresh plasma- healthy women Protein Mass spectrometry 2014 Differential centrifugation|Ultracentrifugation|Filtration|Density gradient centrifugation Exosomes 1076 25104112 Homo sapiens Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. Plasma ts Stored plamsa(freeze/thaw) plasma- healthy women Protein Mass spectrometry 2014 Differential centrifugation|Ultracentrifugation|Filtration|Density gradient centrifugation Exosomes 1077 25104112 Homo sapiens Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. Plasma ts Fresh plasma- healthy women miRNA RT-PCR 2014 Differential centrifugation|Ultracentrifugation|Filtration|Density gradient centrifugation Exosomes 1078 25104112 Homo sapiens Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. Plasma ts Stored plasma(freeze/thaw) plasma- healthy women miRNA RT-PCR 2014 Differential centrifugation|Ultracentrifugation|Filtration|Density gradient centrifugation Exosomes 1079 25104112 Homo sapiens Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. Plasma ts Healthy pregnant women (week 6) Protein ELISA 2014 Differential centrifugation|Ultracentrifugation|Filtration|Density gradient centrifugation Exosomes 1080 25104112 Homo sapiens Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. Plasma ts Healthy pregnant women (week 7) Protein ELISA 2014 Differential centrifugation|Ultracentrifugation|Filtration|Density gradient centrifugation Exosomes 1081 25104112 Homo sapiens Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. Plasma ts Healthy pregnant women (week 8) Protein ELISA 2014 Differential centrifugation|Ultracentrifugation|Filtration|Density gradient centrifugation Exosomes 1082 25104112 Homo sapiens Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. Plasma ts Healthy pregnant women (week 9) Protein ELISA 2014 Differential centrifugation|Ultracentrifugation|Filtration|Density gradient centrifugation Exosomes 1083 25104112 Homo sapiens Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. Plasma ts Healthy pregnant women (week 10) Protein ELISA 2014 Differential centrifugation|Ultracentrifugation|Filtration|Density gradient centrifugation Exosomes 1084 25104112 Homo sapiens Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. Plasma ts Healthy pregnant women (week 11) Protein ELISA 2014 Differential centrifugation|Ultracentrifugation|Filtration|Density gradient centrifugation Exosomes 1085 25104112 Homo sapiens Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. Plasma ts Healthy pregnant women (week 12) Protein ELISA 2014 Differential centrifugation|Ultracentrifugation|Filtration|Density gradient centrifugation Exosomes 1086 25065644 Homo sapiens Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells. Duodenal cancer cells cl AZ-P7a (metastatic) Protein Mass spectrometry 2014 Differential centrifugation|Filtration|Ultrafiltration Exosomes 1087 25065644 Homo sapiens Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells. Duodenal cancer cells cl AZ521 (primary) Protein Mass spectrometry 2014 Differential centrifugation|Filtration|Ultrafiltration Exosomes 1088 25065644 Homo sapiens Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells. Duodenal cancer cells cl AZ-P7a (metastatic) Protein Western blotting 2014 Differential centrifugation|Filtration|Ultrafiltration Exosomes 1089 25065644 Homo sapiens Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells. Duodenal cancer cells cl AZ521 (primary) Protein Western blotting 2014 Differential centrifugation|Filtration|Ultrafiltration Exosomes 1090 25065644 Homo sapiens Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells. Duodenal cancer cells cl AZ-P7a, MG132 treated Protein Western blotting 2014 Differential centrifugation|Filtration|Ultrafiltration Exosomes 1091 25065644 Homo sapiens Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells. Duodenal cancer cells cl AZ-P7a, PYR-41 treated Protein Western blotting 2014 Differential centrifugation|Filtration|Ultrafiltration Exosomes 1092 25065644 Homo sapiens Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells. Duodenal cancer cells cl AZ-P7a, GW4869 treated Protein Western blotting 2014 Differential centrifugation|Filtration|Ultrafiltration Exosomes 1093 25065644 Homo sapiens Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells. Duodenal cancer cells cl AZ-P7a, MON treated Protein Western blotting 2014 Differential centrifugation|Filtration|Ultrafiltration Exosomes 1094 25065644 Homo sapiens Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells. Duodenal cancer cells cl AZ-P7a, BFA treated Protein Western blotting 2014 Differential centrifugation|Filtration|Ultrafiltration Exosomes 1095 24976626 Homo sapiens Exosomal transfer from human renal proximal tubule cells to distal tubule and collecting duct cells. Renal proximal tubule cells cl i16 Protein Mass spectrometry 2014 Differential centrifugation|Ultracentrifugation|Immunoaffinity Exosomes 1096 24976626 Homo sapiens Exosomal transfer from human renal proximal tubule cells to distal tubule and collecting duct cells. Renal proximal tubule cells cl i22 Protein Mass spectrometry 2014 Differential centrifugation|Ultracentrifugation|Immunoaffinity Exosomes 1097 24513287 Mus musculus Lipid synthesis is promoted by hypoxic adipocyte-derived exosomes in 3T3-L1 cells. adipocytes cl 3T3-L1- Normoxic conditions Protein Mass spectrometry 2014 Differential centrifugation|Ultracentrifugation|Filtration Exosomes 1098 24513287 Mus musculus Lipid synthesis is promoted by hypoxic adipocyte-derived exosomes in 3T3-L1 cells. adipocytes cl 3T3-L1- Hypoxic conditions Protein Mass spectrometry 2014 Differential centrifugation|Ultracentrifugation|Filtration Exosomes 1099 24513287 Mus musculus Lipid synthesis is promoted by hypoxic adipocyte-derived exosomes in 3T3-L1 cells. adipocytes cl 3T3-L1- Normoxic conditions Protein Western blotting 2014 Differential centrifugation|Ultracentrifugation|Filtration Exosomes 1100 24513287 Mus musculus Lipid synthesis is promoted by hypoxic adipocyte-derived exosomes in 3T3-L1 cells. adipocytes cl 3T3-L1- Hypoxic conditions Protein Western blotting 2014 Differential centrifugation|Ultracentrifugation|Filtration Exosomes 1101 24513287 Mus musculus Lipid synthesis is promoted by hypoxic adipocyte-derived exosomes in 3T3-L1 cells. Serum ts ob/ob mice (leptin defficient) Protein Western blotting 2014 Differential centrifugation|Ultracentrifugation|Filtration Exosomes 1102 24408433 Prochlorococcus marinus Bacterial vesicles in marine ecosystems. Prochlorococcus marinus cl Strain MED4 Lipids Mass spectrometry 2014 Ultrafiltration|Density gradient centrifugation|Ultracentrifugation Extracellular vesicles 1103 24408433 Prochlorococcus marinus Bacterial vesicles in marine ecosystems. Prochlorococcus marinus cl Strain MIT9313 Lipids Mass spectrometry 2014 Ultrafiltration|Density gradient centrifugation|Ultracentrifugation Extracellular vesicles 1104 24391718 Homo sapiens Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Prostate epithelial cells cl PNT2C2- replicate 1 Protein Mass spectrometry 2013 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 1105 24391718 Homo sapiens Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Prostate epithelial cells cl PNT2C2- replicate 2 Protein Mass spectrometry 2013 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 1106 24391718 Homo sapiens Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Prostate epithelial cells cl PNT2C2- replicate 3 Protein Mass spectrometry 2013 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 1107 24391718 Homo sapiens Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Prostate epithelial cells cl RWPE-1- replicate 1 Protein Mass spectrometry 2013 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 1108 24391718 Homo sapiens Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Prostate epithelial cells cl RWPE-1- replicate 2 Protein Mass spectrometry 2013 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 1109 24391718 Homo sapiens Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Prostate epithelial cells cl RWPE-1- replicate 3 Protein Mass spectrometry 2013 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 1110 24391718 Homo sapiens Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Prostate cancer cells cl PC346C- replicate 1 Protein Mass spectrometry 2013 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 1111 24391718 Homo sapiens Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Prostate cancer cells cl PC346C- replicate 2 Protein Mass spectrometry 2013 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 1112 24391718 Homo sapiens Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Prostate cancer cells cl PC346C- replicate 3 Protein Mass spectrometry 2013 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 1113 24391718 Homo sapiens Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Prostate cancer cells cl VCaP- replicate 1 Protein Mass spectrometry 2013 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 1114 24391718 Homo sapiens Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Prostate cancer cells cl VCaP- replicate 2 Protein Mass spectrometry 2013 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 1115 24391718 Homo sapiens Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Prostate cancer cells cl VCaP- replicate 3 Protein Mass spectrometry 2013 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 1116 24391718 Homo sapiens Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Prostate epithelial cells cl PNT2C2 Protein Western blotting 2013 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 1117 24391718 Homo sapiens Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Prostate epithelial cells cl RWPE-1 Protein Western blotting 2013 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 1118 24391718 Homo sapiens Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Prostate cancer cells cl PC346C Protein Western blotting 2013 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 1119 24391718 Homo sapiens Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Prostate cancer cells cl VCaP Protein Western blotting 2013 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 1120 24347249 Homo sapiens Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules. Prostate cancer cells cl LNCaP- Normoxic Protein Mass spectrometry 2015 Differential centrifugation|Ultracentrifugation|ExoQuick Exosomes 1121 24347249 Homo sapiens Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules. Prostate cancer cells cl LNCaP- Hypoxic Protein Mass spectrometry 2015 Differential centrifugation|Ultracentrifugation|ExoQuick Exosomes 1122 24347249 Homo sapiens Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules. Prostate cancer cells cl LNCaP- Normoxic Protein Western blotting 2015 Differential centrifugation|Ultracentrifugation|ExoQuick Exosomes 1123 24347249 Homo sapiens Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules. Prostate cancer cells cl LNCaP- Hypoxic Protein Western blotting 2015 Differential centrifugation|Ultracentrifugation|ExoQuick Exosomes 1124 24347249 Homo sapiens Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules. Prostate cancer cells cl LNCaP- Normoxic Protein Zymogram assay 2015 Differential centrifugation|Ultracentrifugation|ExoQuick Exosomes 1125 24347249 Homo sapiens Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules. Prostate cancer cells cl LNCaP- Hypoxic Protein Zymogram assay 2015 Differential centrifugation|Ultracentrifugation|ExoQuick Exosomes 1126 24295599 Mus musculus Exosomes from myeloid-derived suppressor cells carry biologically active proteins. Myeloid-derived suppressor cells cl Conventional MDSC's-BALB/c mice injected with 4T1 cells Protein Mass spectrometry 2014 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 1127 24295599 Mus musculus Exosomes from myeloid-derived suppressor cells carry biologically active proteins. Myeloid-derived suppressor cells cl Inflammatory MDSC's-BALB/c mice injected with 4T1 cells expressing IL-1. Protein Mass spectrometry 2014 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Exosomes 1128 23954818 Homo sapiens Qualitative changes in the proteome of extracellular vesicles accompanying cancer cell transition to mesenchymal state. Squamous carcinoma cells cl Normal A431 Protein Mass spectrometry 2013 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1129 23954818 Homo sapiens Qualitative changes in the proteome of extracellular vesicles accompanying cancer cell transition to mesenchymal state. Squamous carcinoma cells cl Mesenchymal A431 (SHE78-7/TGF. treated) Protein Mass spectrometry 2013 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1130 23954818 Homo sapiens Qualitative changes in the proteome of extracellular vesicles accompanying cancer cell transition to mesenchymal state. Squamous carcinoma cells cl Normal A431 Protein Western blotting 2013 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1131 23954818 Homo sapiens Qualitative changes in the proteome of extracellular vesicles accompanying cancer cell transition to mesenchymal state. Squamous carcinoma cells cl Mesenchymal A431 (SHE78-7/TGF. treated) Protein Western blotting 2013 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1132 23861904 Homo sapiens Exosomal signaling during hypoxia mediates microvascular endothelial cell migration and vasculogenesis. Placental mesenchymal stem cells cl pMSC's in 1% Oxygen Protein Western blotting 2013 Differential centrifugation|Ultracentrifugation|Ultrafiltration|Density gradient centrifugation Exosomes 1133 23861904 Homo sapiens Exosomal signaling during hypoxia mediates microvascular endothelial cell migration and vasculogenesis. Placental mesenchymal stem cells cl pMSC's in 3% Oxygen Protein Western blotting 2013 Differential centrifugation|Ultracentrifugation|Ultrafiltration|Density gradient centrifugation Exosomes 1134 23861904 Homo sapiens Exosomal signaling during hypoxia mediates microvascular endothelial cell migration and vasculogenesis. Placental mesenchymal stem cells cl pMSC's in 8% Oxygen Protein Western blotting 2013 Differential centrifugation|Ultracentrifugation|Ultrafiltration|Density gradient centrifugation Exosomes 1135 23861904 Homo sapiens Exosomal signaling during hypoxia mediates microvascular endothelial cell migration and vasculogenesis. Placental mesenchymal stem cells cl pMSC's in 1% Oxygen Protein Mass spectrometry 2013 Differential centrifugation|Ultracentrifugation|Ultrafiltration|Density gradient centrifugation Exosomes 1136 23861904 Homo sapiens Exosomal signaling during hypoxia mediates microvascular endothelial cell migration and vasculogenesis. Placental mesenchymal stem cells cl pMSC's in 3% Oxygen Protein Mass spectrometry 2013 Differential centrifugation|Ultracentrifugation|Ultrafiltration|Density gradient centrifugation Exosomes 1137 23861904 Homo sapiens Exosomal signaling during hypoxia mediates microvascular endothelial cell migration and vasculogenesis. Placental mesenchymal stem cells cl pMSC's in 8% Oxygen Protein Mass spectrometry 2013 Differential centrifugation|Ultracentrifugation|Ultrafiltration|Density gradient centrifugation Exosomes 1138 23707955 Homo sapiens Prostasomes from four different species are able to produce extracellular adenosine triphosphate (ATP). Seminal plasma ts normal male Protein Mass spectrometry 2013 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Prostasomes 1139 23707955 Bos taurus Prostasomes from four different species are able to produce extracellular adenosine triphosphate (ATP). Seminal plasma ts normal male Protein Mass spectrometry 2013 Differential centrifugation|Ultracentrifugation|Density gradient centrifugation Prostasomes 1140 23454749 Homo sapiens BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression. Bone marrow mesenchymal stromal cells cl Normal patient Protein Immunoelectron microscopy|Western blotting 2013 Differential centrifugation|Ultracentrifugation|Filtration|ExoQuick Exosomes 1141 23454749 Homo sapiens BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression. Bone marrow mesenchymal stromal cells cl Multiple myeloma patient Protein Immunoelectron microscopy|Western blotting 2013 Differential centrifugation|Ultracentrifugation|Filtration|ExoQuick Exosomes 1142 23454749 Homo sapiens BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression. Bone marrow mesenchymal stromal cells cl HS-5 Protein Western blotting 2013 Differential centrifugation|Ultracentrifugation|Filtration|ExoQuick Exosomes 1143 23454749 Homo sapiens BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression. Bone marrow mesenchymal stromal cells cl Normal patient Protein Western blotting 2013 Differential centrifugation|Ultracentrifugation|Filtration|ExoQuick Exosomes 1144 23454749 Homo sapiens BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression. Bone marrow mesenchymal stromal cells cl Multiple myeloma patient Protein Western blotting 2013 Differential centrifugation|Ultracentrifugation|Filtration|ExoQuick Exosomes 1145 23173708 Rattus norvegicus Wnt3a induces exosome secretion from primary cultured rat microglia. Primary microglial cells cl Wnt3a stimulated (8 hour)|100,000g fraction Protein Mass spectrometry 2012 Differential centrifugation|Ultracentrifugation Exosomes 1146 23173708 Rattus norvegicus Wnt3a induces exosome secretion from primary cultured rat microglia. Primary microglial cells cl Wnt3a stimulated (8 hour)|100,000g fraction Protein Western blotting 2012 Differential centrifugation|Ultracentrifugation Exosomes 1147 23173708 Rattus norvegicus Wnt3a induces exosome secretion from primary cultured rat microglia. Primary microglial cells cl Wnt3a stimulated (36 hour)|100,000g fraction Protein Western blotting 2012 Differential centrifugation|Ultracentrifugation Exosomes 1148 23173708 Rattus norvegicus Wnt3a induces exosome secretion from primary cultured rat microglia. Primary microglial cells cl Wnt3a stimulated (36 hour)|200,000g fraction Protein Western blotting 2012 Differential centrifugation|Ultracentrifugation Exosomes 1149 22807456 Homo sapiens Quantitative proteomic analysis of exosomes from HIV-1-infected lymphocytic cells. Lymphocytes cl H9 cells uninfected Protein Western blotting 2012 Differential centrifugation|Ultracentrifugation Exosomes 1150 22807456 Homo sapiens Quantitative proteomic analysis of exosomes from HIV-1-infected lymphocytic cells. Lymphocytes cl H9 cells HIV-1NL4.3 infected Protein Western blotting 2012 Differential centrifugation|Ultracentrifugation Exosomes 1151 22367951 Acinetobacter baumannii Acinetobacter baumannii outer membrane protein A modulates the biogenesis of outer membrane vesicles. Acinetobacter baumannii cl .AbOmpA mutant Protein Mass spectrometry 2012 Differential centrifugation|Ultrafiltration|Ultracentrifugation Outer membrane vesicles 1152 22057275 Homo sapiens Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease. Neuroblastoma cells cl M1C cells (inducibly expressing wild-type human tau Protein Western blotting 2012 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1153 22057275 Homo sapiens Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease. Neuroblastoma cells cl M1C cells (inducibly expressing wild-type human tau Protein Mass spectrometry 2012 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1154 22057275 Homo sapiens Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease. Cerebrospinal fluid cl Alzheimer's disease patients Protein Western blotting 2012 Differential centrifugation|Filtration|Ultracentrifugation|Density gradient centrifugation Exosomes 1155 21212511 Homo sapiens Proteomic analysis of two types of exosomes in human whole saliva. Saliva ts Exosome I Protein Western blotting 2011 Differential centrifugation|Filtration|Ultracentrifugation|Gel filtration Exosomes 1156 21212511 Homo sapiens Proteomic analysis of two types of exosomes in human whole saliva. Saliva ts Exosome II Protein Western blotting 2011 Differential centrifugation|Filtration|Ultracentrifugation|Gel filtration Exosomes 1157 20662102 Mus musculus Proteomic analysis identifies highly antigenic proteins in exosomes from M. tuberculosis-infected and culture filtrate protein-treated macrophages. Macrophage cl J774 infected with M.tubelrculosis H37Rv Protein Western blotting 2010 Differential centrifugation|Filtration|Ultracentrifugation|Density gradient centrifugation Exosomes 1158 20662102 Mus musculus Proteomic analysis identifies highly antigenic proteins in exosomes from M. tuberculosis-infected and culture filtrate protein-treated macrophages. Macrophage cl J774 (uninfected) Protein Western blotting 2010 Differential centrifugation|Filtration|Ultracentrifugation|Density gradient centrifugation Exosomes 1159 20409149 Homo sapiens Transdifferentiated circulating monocytes release exosomes containing 14-3-3 proteins with matrix metalloproteinase-1 stimulating effect for dermal fibroblasts. Keratinocytes cl KLC's Protein Western blotting 2010 Differential centrifugation|Filtration|Ultrafiltration|Ultracentrifugation|Sucrose density gradient Exosomes 1160 22641613 Homo sapiens Application of systems biology principles to protein biomarker discovery: urinary exosomal proteome in renal transplantation. Urine ts Renal allograft recipient with tubular injury Protein Mass spectrometry 2012 Differential centrifugation|Ultracentrifugation Exosomes 1161 22641613 Homo sapiens Application of systems biology principles to protein biomarker discovery: urinary exosomal proteome in renal transplantation. Urine ts Renal allograft recipient with cell-mediated rejection Protein Mass spectrometry 2012 Differential centrifugation|Ultracentrifugation Exosomes 1162 22641613 Homo sapiens Application of systems biology principles to protein biomarker discovery: urinary exosomal proteome in renal transplantation. Urine ts Renal allograft recipient with acute inflamatory response Protein Mass spectrometry 2012 Differential centrifugation|Ultracentrifugation Exosomes 1163 29904572 Bos taurus A subset of extracellular vesicles carries the bulk of microRNAs in commercial dairy cow's milk. Bovine milk ts Pellet, 12000 g Protein|miRNA Mass spectrometry|Western blotting 2017 Differential centrifugation|Density gradient centrifugation Extracellular vesicles 1164 29904572 Bos taurus A subset of extracellular vesicles carries the bulk of microRNAs in commercial dairy cow's milk. Bovine milk ts Pellet, 35000 g Protein|miRNA Mass spectrometry|Western blotting 2017 Differential centrifugation|Density gradient centrifugation Extracellular vesicles 1165 29904572 Bos taurus A subset of extracellular vesicles carries the bulk of microRNAs in commercial dairy cow's milk. Bovine milk ts Pellet, 70000 g Protein|miRNA Mass spectrometry|Western blotting 2017 Differential centrifugation|Density gradient centrifugation Extracellular vesicles 1166 29904572 Bos taurus A subset of extracellular vesicles carries the bulk of microRNAs in commercial dairy cow's milk. Bovine milk ts Pellet, 100000 g Protein|miRNA Mass spectrometry|Western blotting 2017 Differential centrifugation|Density gradient centrifugation Extracellular vesicles 1167 29907695 Mus musculus Cancer cells copy migratory behavior and exchange signaling networks via extracellular vesicles. Melanoma cells cl B16F1 (16.5 K) Protein|miRNA Mass spectrometry|RNA sequencing 2018 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1168 29907695 Mus musculus Cancer cells copy migratory behavior and exchange signaling networks via extracellular vesicles. Melanoma cells cl B16F10 (16.5 K) Protein|miRNA Mass spectrometry|RNA sequencing 2018 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1169 29907695 Mus musculus Cancer cells copy migratory behavior and exchange signaling networks via extracellular vesicles. Melanoma cells cl B16F1 (100 K) Protein|miRNA Mass spectrometry|RNA sequencing 2018 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1170 29907695 Mus musculus Cancer cells copy migratory behavior and exchange signaling networks via extracellular vesicles. Melanoma cells cl B16F10 (100 K) Protein|miRNA Mass spectrometry|RNA sequencing 2018 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1171 29881354 Rattus norvegicus Effects of Acute Aerobic Exercise on Rats Serum Extracellular Vesicles Diameter, Concentration and Small RNAs Content. Serum ts Non-exercised rats Protein|miRNA RNA sequencing 2018 ExoQuick Extracellular vesicles 1172 29881354 Rattus norvegicus Effects of Acute Aerobic Exercise on Rats Serum Extracellular Vesicles Diameter, Concentration and Small RNAs Content. Serum ts Low-exercised rats Protein|miRNA RNA sequencing 2018 ExoQuick Extracellular vesicles 1173 29881354 Rattus norvegicus Effects of Acute Aerobic Exercise on Rats Serum Extracellular Vesicles Diameter, Concentration and Small RNAs Content. Serum ts Moderate-exercised rats Protein|miRNA RNA sequencing 2018 ExoQuick Extracellular vesicles 1174 29881354 Rattus norvegicus Effects of Acute Aerobic Exercise on Rats Serum Extracellular Vesicles Diameter, Concentration and Small RNAs Content. Serum ts High-exercised rats Protein|miRNA RNA sequencing 2018 ExoQuick Extracellular vesicles 1175 29854963 Homo sapiens Genome-wide Profiling of Urinary Extracellular Vesicle microRNAs Associated With Diabetic Nephropathy in Type 1 Diabetes. Urine ts Normal patient miRNA RNA sequencing|qPCR 2017 qEV size-exclusion column Extracellular vesicles 1176 29854963 Homo sapiens Genome-wide Profiling of Urinary Extracellular Vesicle microRNAs Associated With Diabetic Nephropathy in Type 1 Diabetes. Urine ts Overt patient miRNA RNA sequencing|qPCR 2017 qEV size-exclusion column Extracellular vesicles 1177 29854963 Homo sapiens Genome-wide Profiling of Urinary Extracellular Vesicle microRNAs Associated With Diabetic Nephropathy in Type 1 Diabetes. Urine ts Persistent patient miRNA RNA sequencing|qPCR 2017 qEV size-exclusion column Extracellular vesicles 1178 29854963 Homo sapiens Genome-wide Profiling of Urinary Extracellular Vesicle microRNAs Associated With Diabetic Nephropathy in Type 1 Diabetes. Urine ts Intermittent patient miRNA RNA sequencing|qPCR 2017 qEV size-exclusion column Extracellular vesicles 1179 29854963 Homo sapiens Genome-wide Profiling of Urinary Extracellular Vesicle microRNAs Associated With Diabetic Nephropathy in Type 1 Diabetes. Urine ts Persistent MA patient miRNA RNA sequencing|qPCR 2017 qEV size-exclusion column Extracellular vesicles 1180 29854963 Homo sapiens Genome-wide Profiling of Urinary Extracellular Vesicle microRNAs Associated With Diabetic Nephropathy in Type 1 Diabetes. Urine ts Intermittent MA patient miRNA RNA sequencing|qPCR 2017 qEV size-exclusion column Extracellular vesicles 1181 28684402 Homo sapiens BRAFV600 inhibition alters the microRNA cargo in the vesicular secretome of malignant melanoma cells Melanoma cells cl MML-1 cells miRNA Next generation sequencing|qPCR 2017 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1182 28684402 Homo sapiens BRAFV600 inhibition alters the microRNA cargo in the vesicular secretome of malignant melanoma cells Melanoma cells cl MML-1 cells treated with Vemurafenib miRNA Next generation sequencing|qPCR 2017 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1183 28684402 Homo sapiens BRAFV600 inhibition alters the microRNA cargo in the vesicular secretome of malignant melanoma cells Melanoma cells cl A375 treated with Vemurafenib miRNA Next generation sequencing|qPCR 2017 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1184 28684402 Homo sapiens BRAFV600 inhibition alters the microRNA cargo in the vesicular secretome of malignant melanoma cells Melanoma cells cl MML-1 cells treated with dabrafenib miRNA Next generation sequencing|qPCR 2017 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1185 28042326 Homo sapiens Exosomes derived from miR-140-5p-overexpressing human synovial mesenchymal stem cells enhance cartilage tissue regeneration and prevent osteoarthritis of the knee in a rat model. Synovial mesenchymal stem cells ts SMSCs miRNA qPCR|Western blotting 2017 Differential centrifugation|Filtration|Sucrose density gradient Exosomes 1186 28326167 Homo sapiens Residual urinary extracellular vesicles in ultracentrifugation supernatants after hydrostatic filtration dialysis enrichment. Urine ts Pelelt, HFDa P40 Protein Mass spectrometry|Western blotting 2016 Hydrostatic filtration dialysis|Differential centrifugation|Ultracentrifugation Extracellular vesicles 1187 28326167 Homo sapiens Residual urinary extracellular vesicles in ultracentrifugation supernatants after hydrostatic filtration dialysis enrichment. Urine ts Pelelt, HFDa P200 Protein Mass spectrometry|Western blotting 2016 Hydrostatic filtration dialysis|Differential centrifugation|Ultracentrifugation Extracellular vesicles 1188 28326167 Homo sapiens Residual urinary extracellular vesicles in ultracentrifugation supernatants after hydrostatic filtration dialysis enrichment. Urine ts Pelelt, HFDa SN200 Protein Mass spectrometry|Western blotting 2016 Hydrostatic filtration dialysis|Differential centrifugation|Ultracentrifugation Extracellular vesicles 1189 28326167 Homo sapiens Residual urinary extracellular vesicles in ultracentrifugation supernatants after hydrostatic filtration dialysis enrichment. Urine ts Pelelt, HFDa Protein Mass spectrometry|Western blotting 2016 Hydrostatic filtration dialysis|Differential centrifugation|Ultracentrifugation Extracellular vesicles 1190 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer. Prostate cancer cells cl LNCaP Protein Mass spectrometry|Western blotting 2016 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1191 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer. Prostate cancer cells cl LNCaP, DHT treatment Protein Mass spectrometry|Western blotting 2016 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1192 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer. Prostate cancer cells cl LNCaP, EtOH Protein Mass spectrometry|Western blotting 2016 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1193 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer. Prostate cancer cells cl DUCaP Protein Mass spectrometry|Western blotting 2016 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1194 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer. Prostate cancer cells cl DUCaP, DHT treatment Protein Mass spectrometry|Western blotting 2016 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1195 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer. Prostate cancer cells cl DUCaP, EtOH Protein Mass spectrometry|Western blotting 2016 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1196 27883272 Homo sapiens Circulating adipocyte-derived exosomal MicroRNAs associated with decreased insulin resistance after gastric bypass. Plasma ts Two weeks before bariatric surgery miRNA|Metabolites Microarray 2017 ExoQuick Exosomes 1197 27883272 Homo sapiens Circulating adipocyte-derived exosomal MicroRNAs associated with decreased insulin resistance after gastric bypass. Plasma ts One year after bariatric surgery miRNA|Metabolites Microarray 2017 ExoQuick Exosomes 1198 27883272 Homo sapiens Circulating adipocyte-derived exosomal MicroRNAs associated with decreased insulin resistance after gastric bypass. Serum ts Two weeks before bariatric surgery miRNA|Metabolites Mass spectrometry 2017 ExoQuick Exosomes 1199 27883272 Homo sapiens Circulating adipocyte-derived exosomal MicroRNAs associated with decreased insulin resistance after gastric bypass. Serum ts One year after bariatric surgery miRNA|Metabolites Mass spectrometry 2017 ExoQuick Exosomes 1200 27780738 Homo sapiens Next-generation sequencing-based small RNA profiling of cerebrospinal fluid exosomes. Cerebrospinal fluid ts Healthy donor 1 miRNA Next generation sequencing 2017 Differential centrifugation|Ultracentrifugation Exosomes 1201 27780738 Homo sapiens Next-generation sequencing-based small RNA profiling of cerebrospinal fluid exosomes. Cerebrospinal fluid ts Healthy donor 2 miRNA Next generation sequencing 2017 Differential centrifugation|Ultracentrifugation Exosomes 1202 27780738 Homo sapiens Next-generation sequencing-based small RNA profiling of cerebrospinal fluid exosomes. Cerebrospinal fluid ts Cerebrospinal fluid miRNA Next generation sequencing 2017 Differential centrifugation|Ultracentrifugation Exosomes 1203 27780738 Homo sapiens Next-generation sequencing-based small RNA profiling of cerebrospinal fluid exosomes. Serum ts Healthy donor 1 miRNA Next generation sequencing 2017 Differential centrifugation|Ultracentrifugation Exosomes 1204 27780738 Homo sapiens Next-generation sequencing-based small RNA profiling of cerebrospinal fluid exosomes. Serum ts Healthy donor 2 miRNA Next generation sequencing 2017 Differential centrifugation|Ultracentrifugation Exosomes 1205 27780738 Homo sapiens Next-generation sequencing-based small RNA profiling of cerebrospinal fluid exosomes. Serum ts Serum miRNA Next generation sequencing 2017 Differential centrifugation|Ultracentrifugation Exosomes 1206 29127410 Homo sapiens Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. Bronchial epithelial cells cl BEAS-2B untreated Protein Western blotting 2017 Ultrafiltration|Size exclusion chromatography Extracellular vesicles 1207 29127410 Homo sapiens Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. Bronchial epithelial cells cl Ultrafiltration and size exclusion chromatography sample 1 Protein Mass spectrometry 2017 Ultrafiltration|Size exclusion chromatography Extracellular vesicles 1208 29127410 Homo sapiens Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. Bronchial epithelial cells cl Ultrafiltration and size exclusion chromatography sample 2 Protein Mass spectrometry 2017 Ultrafiltration|Size exclusion chromatography Extracellular vesicles 1209 29127410 Homo sapiens Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. Bronchial epithelial cells cl Ultrafiltration and size exclusion chromatography sample 3 Protein Mass spectrometry 2017 Ultrafiltration|Size exclusion chromatography Extracellular vesicles 1210 29127410 Homo sapiens Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. Bronchial epithelial cells cl Ultrafiltration and size exclusion chromatography sample 4 Protein Mass spectrometry 2017 Ultrafiltration|Size exclusion chromatography Extracellular vesicles 1211 29127410 Homo sapiens Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. Bronchial epithelial cells cl Ultrafiltration and size exclusion chromatography sample 5 Protein Mass spectrometry 2017 Ultrafiltration|Size exclusion chromatography Extracellular vesicles 1212 29127410 Homo sapiens Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. Bronchial epithelial cells cl Ultracentrifugation, sample 1 Protein Mass spectrometry 2017 Ultracentrifugation Extracellular vesicles 1213 29127410 Homo sapiens Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. Bronchial epithelial cells cl Ultracentrifugation, sample 2 Protein Mass spectrometry 2017 Ultracentrifugation Extracellular vesicles 1214 29127410 Homo sapiens Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. Bronchial epithelial cells cl Ultracentrifugation, sample 3 Protein Mass spectrometry 2017 Ultracentrifugation Extracellular vesicles 1215 27872147 Rattus norvegicus Primary Human and Rat .-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity. Islets ts Rat interleukin (IL)-1. (10 units/mL)- 4h Protein Western blotting 2017 Differential centrifugation|Ultracentrifugation Exosomes 1216 27872147 Rattus norvegicus Primary Human and Rat .-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity. Islets ts Rat interleukin (IL)-1. (10 units/mL)- 8h Protein Western blotting 2017 Differential centrifugation|Ultracentrifugation Exosomes 1217 27872147 Rattus norvegicus Primary Human and Rat .-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity. Islets ts Rat interleukin (IL)-1. (10 units/mL)- 24h Protein Western blotting 2017 Differential centrifugation|Ultracentrifugation Exosomes 1218 27872147 Homo sapiens Primary Human and Rat .-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity. Islets ts Human IL-1. (20 units/mL) Protein Western blotting|Mass spectrometry 2017 Differential centrifugation|Ultracentrifugation Exosomes 1219 27872147 Homo sapiens Primary Human and Rat .-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity. Islets ts HmanIFN-. (10 units/mL) Protein Western blotting 2017 Differential centrifugation|Ultracentrifugation Exosomes 1220 27872147 Rattus norvegicus Primary Human and Rat .-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity. Insulinoma cells cl INS-1E cells Protein Mass spectrometry 2017 Differential centrifugation|Ultracentrifugation Exosomes 1221 27872147 Rattus norvegicus Primary Human and Rat .-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity. Insulinoma cells ts Rat interleukin (IL)-1. (10 units/mL) Protein Mass spectrometry 2017 Differential centrifugation|Ultracentrifugation Exosomes 1222 26272980 Homo sapiens Proteomic Profiling of Detergent Resistant Membranes (Lipid Rafts) of Prostasomes Seminal plasma ts Seminal plasma Protein Mass spectrometry 2015 Ultracentrifugation|Density gradient centrifugation Prostasomes 1223 26154623 Homo sapiens Size-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals Plasma ts Donar 1 Protein Mass spectrometry 2015 Exo-spin Extracellular vesicles 1224 26154623 Homo sapiens Size-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals Plasma ts Donar 2 Protein Mass spectrometry 2015 Exo-spin Extracellular vesicles 1225 26154623 Homo sapiens Size-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals Plasma ts Donar 3 Protein Mass spectrometry 2015 Exo-spin Extracellular vesicles 1226 26154623 Homo sapiens Size-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals Plasma ts Donar 1 fr7+8 Protein Mass spectrometry 2015 Size exclusion chromatography Extracellular vesicles 1227 26154623 Homo sapiens Size-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals Plasma ts Donar 1 fr9+10 Protein Mass spectrometry 2015 Size exclusion chromatography Extracellular vesicles 1228 26154623 Homo sapiens Size-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals Plasma ts Donar fr11 Protein Mass spectrometry 2015 Size exclusion chromatography Extracellular vesicles 1229 26154623 Homo sapiens Size-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals Plasma ts Donar 3 fr8 Protein Mass spectrometry 2015 Size exclusion chromatography Extracellular vesicles 1230 25503107 Homo sapiens Tumor-derived microvesicles mediate human breast cancer invasion through differentially glycosylated EMMPRIN. Breast cancer cells cl MCF-7 Protein Mass spectrometry|Western blotting 2015 Ultracentrifugation|Filtration|Density gradient centrifugation Microvesicles 1231 25503107 Homo sapiens Tumor-derived microvesicles mediate human breast cancer invasion through differentially glycosylated EMMPRIN. Breast cancer cells cl SK-BR-3 Protein Mass spectrometry|Western blotting 2015 Ultracentrifugation|Filtration|Density gradient centrifugation Microvesicles 1232 25475747 Homo sapiens Identification of Biomarkers for PKD1 Using Urinary Exosomes Urine ts Healthy Protein Mass spectrometry|Western blotting 2014 Ultracentrifugation|Density gradient centrifugation Extracellular vesicles 1233 25469510 Homo sapiens GAIP interacting protein C-terminus regulates autophagy and exosome biogenesis of pancreatic cancer through metabolic pathways. Pancreatic cancer cells cl PANC-1 Protein Western blotting 2015 Differential centrifugation|Ultracentrifugation Exosomes 1234 25421927 Mus musculus Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity. Serum ts 14 days post infection miRNA|Protein RT.qpcr|HPLC-MS/MS 2014 Filtration|Ultracentrifugation Exosomes 1235 25421927 Heligmosomoides polygyrus Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity. Heligmosomoides polygyrus cl Supernatant, Secretion product replicate 1 miRNA|Protein RT.qpcr|HPLC-MS/MS 2014 Filtration|Ultracentrifugation Exosomes 1236 25421927 Heligmosomoides polygyrus Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity. Heligmosomoides polygyrus cl Supernatant, Secretion product replicate 2 miRNA|Protein RT.qpcr|HPLC-MS/MS 2014 Filtration|Ultracentrifugation Exosomes 1237 25421927 Heligmosomoides polygyrus Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity. Heligmosomoides polygyrus cl Supernatant, Secretion product replicate 3 miRNA|Protein RT.qpcr|HPLC-MS/MS 2014 Filtration|Ultracentrifugation Exosomes 1238 25329303 Homo sapiens Rapid isolation of extracellular vesicles from cell culture and biological fluids using a synthetic peptide with specific affinity for heat shock proteins. Urine ts Pre-digital rectal exam Protein Western blotting 2014 Ultracentrifugation Extracellular vesicles 1239 25329303 Homo sapiens Rapid isolation of extracellular vesicles from cell culture and biological fluids using a synthetic peptide with specific affinity for heat shock proteins. Urine ts Pre-digital rectal exam Protein Western blotting 2014 Vn96 peptide precipitation Extracellular vesicles 1240 25329303 Homo sapiens Rapid isolation of extracellular vesicles from cell culture and biological fluids using a synthetic peptide with specific affinity for heat shock proteins. Urine ts Post-digital rectal exam Protein Western blotting 2014 Ultracentrifugation Extracellular vesicles 1241 25329303 Homo sapiens Rapid isolation of extracellular vesicles from cell culture and biological fluids using a synthetic peptide with specific affinity for heat shock proteins. Urine ts Post-digital rectal exam Protein Western blotting 2014 Vn96 peptide precipitation Extracellular vesicles 1242 25261722 Homo sapiens Inflammatory cytokines, interleukin-1 beta and tumor necrosis factor-alpha, upregulated in glioblastoma multiforme, raise the levels of CRYAB in exosomes secreted by U373 glioma cells. Glioblastoma cells cl U373 cells treated with 10ng/ml of IL-1. Protein Mass spectrometry|Western blotting 2014 Differential centrifugation|Ultracentrifugation Exosomes 1243 25261722 Homo sapiens Inflammatory cytokines, interleukin-1 beta and tumor necrosis factor-alpha, upregulated in glioblastoma multiforme, raise the levels of CRYAB in exosomes secreted by U373 glioma cells. Glioblastoma cells cl U373 cells treated with 10ng/ml of TNF-. Protein Mass spectrometry|Western blotting 2014 Differential centrifugation|Ultracentrifugation Exosomes 1244 25167841 Homo sapiens Antibody-coupled monolithic silica microtips for highthroughput molecular profiling of circulating exosomes. Serum ts Normal controls Protein Mass spectrometry 2014 CD9 antibody to Mass Spectrometric Immunoassay monolith pipette tips Exosomes 1245 25167841 Homo sapiens Antibody-coupled monolithic silica microtips for highthroughput molecular profiling of circulating exosomes. Serum ts Interstitial pneumonia patients Protein Mass spectrometry 2014 CD9 antibody to Mass Spectrometric Immunoassay monolith pipette tips Exosomes 1246 25167841 Homo sapiens Antibody-coupled monolithic silica microtips for highthroughput molecular profiling of circulating exosomes. Serum ts Lung adenocarcinoma patients Protein Mass spectrometry 2014 CD9 antibody to Mass Spectrometric Immunoassay monolith pipette tips Exosomes 1247 25167841 Homo sapiens Antibody-coupled monolithic silica microtips for highthroughput molecular profiling of circulating exosomes. Serum ts Lung squamous cell carcinoma patients Protein Mass spectrometry 2014 CD9 antibody to Mass Spectrometric Immunoassay monolith pipette tips Exosomes 1248 24939845 Homo sapiens Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein. Leukemia cells cl CEM - uninfected Protein Mass spectrometry|Western blotting 2014 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1249 24939845 Homo sapiens Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein. Leukemia cells cl C81 - HTLV-1 infected Protein Mass spectrometry|Western blotting 2014 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1250 24939845 Homo sapiens Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein. Leukemia cells cl MT2 - HTLV-1 infected Protein Mass spectrometry|Western blotting 2014 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1251 24939845 Homo sapiens Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein. Leukemia cells cl ED-40515 -HTLV-1 infected Protein Mass spectrometry|Western blotting 2014 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1252 24939845 Homo sapiens Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein. T cells cl Jurkat T-cells Protein Western blotting 2014 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1253 24939845 Homo sapiens Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein. T cells cl Jurkat T-cells with pACH Protein Western blotting 2014 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1254 24468161 Homo sapiens Molecular characterization of exosome-like vesicles from breast cancer cells. Breast cancer cells cl MCF7 Protein|miRNA Mass spectrometry|Microarray|RT-PCR|Western blotting 2014 Differential centrifugation|Filtration|Ultracentrifugation|Density gradient centrifugation Extracellular vesicles 1255 24468161 Homo sapiens Molecular characterization of exosome-like vesicles from breast cancer cells. Breast cancer cells cl MDA-MB231 Protein|miRNA Mass spectrometry|Microarray|RT-PCR|Western blotting 2014 Differential centrifugation|Filtration|Ultracentrifugation|Density gradient centrifugation Extracellular vesicles 1256 24400796 Homo sapiens Exosomal proteins in the aqueous humor as novel biomarkers in patients with neovascular age-related macular degeneration. Retinal pigment epithelial cells cl ARPE-19 Protein Mass spectrometry|Western blotting 2014 ExoQuick Exosomes 1257 24400796 Homo sapiens Exosomal proteins in the aqueous humor as novel biomarkers in patients with neovascular age-related macular degeneration. Retinal pigment epithelial cells cl ARPE-19 400 µM paraquat Protein Mass spectrometry|Western blotting 2014 ExoQuick Exosomes 1258 24400796 Homo sapiens Exosomal proteins in the aqueous humor as novel biomarkers in patients with neovascular age-related macular degeneration. Aqueous humor ts Age-related macular degeneration patients Protein Mass spectrometry|Western blotting 2014 ExoQuick Exosomes 1259 24400796 Rattus norvegicus Exosomal proteins in the aqueous humor as novel biomarkers in patients with neovascular age-related macular degeneration. Retinal glial cells ts Mücells Protein Mass spectrometry 2014 ExoQuick Exosomes 1260 24371517 Homo sapiens Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients. Prostate cancer cells cl LNCaP Protein Mass spectrometry|Western blotting 2013 Differential centrifugation|Ultracentrifugation Exosomes 1261 24371517 Homo sapiens Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients. Prostate cancer cells cl PC3 Protein Mass spectrometry|Western blotting 2013 Differential centrifugation|Ultracentrifugation Exosomes 1262 24371517 Homo sapiens Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients. Urine ts Benign prostate hyperplasia Protein Western blotting 2013 Differential centrifugation|Ultracentrifugation Exosomes 1263 24371517 Homo sapiens Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients. Urine ts Prostate cancer Protein Western blotting 2013 Differential centrifugation|Ultracentrifugation Exosomes 1264 24371517 Homo sapiens Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients. Urine ts Metastatic prostate cancer Protein Western blotting 2013 Differential centrifugation|Ultracentrifugation Exosomes 1265 24310399 Homo sapiens Extracellular vesicles modulate the glioblastoma microenvironment via a tumor suppression signaling network directed by miR-1. Glioblastoma cells cl U87 cells - control Protein Mass spectrometry 2014 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1266 24310399 Homo sapiens Extracellular vesicles modulate the glioblastoma microenvironment via a tumor suppression signaling network directed by miR-1. Glioblastoma cells cl U87 cells + miRNA-1 Protein Mass spectrometry 2014 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1267 24218614 Homo sapiens Unexpected gain of function for the scaffolding protein plectin due to mislocalization in pancreatic cancer. Pancreatic cancer cells cl Bxpc 3 Cells Protein Western blotting 2013 Differential centrifugation|Ultracentrifugation Exosomes 1268 24218614 Homo sapiens Unexpected gain of function for the scaffolding protein plectin due to mislocalization in pancreatic cancer. Pancreatic cancer cells cl Panc-1 Protein Western blotting 2013 Differential centrifugation|Ultracentrifugation Exosomes 1269 24218614 Homo sapiens Unexpected gain of function for the scaffolding protein plectin due to mislocalization in pancreatic cancer. Pancreatic cancer cells cl L3.6pl- wild type cells Protein Mass spectrometry|Western blotting 2013 Differential centrifugation|Ultracentrifugation Exosomes 1270 24218614 Homo sapiens Unexpected gain of function for the scaffolding protein plectin due to mislocalization in pancreatic cancer. Pancreatic cancer cells cl L3.6pl- plectin knockdown Protein Mass spectrometry|Western blotting 2013 Differential centrifugation|Ultracentrifugation Exosomes 1271 24058411 Homo sapiens Osteoprotegerin in exosome-like vesicles from human cultured tubular cells and urine. Proximal tubular epithelial cells cl HK-2 Protein Mass spectrometry|Western blotting 2013 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1272 24058411 Homo sapiens Osteoprotegerin in exosome-like vesicles from human cultured tubular cells and urine. Urine ts Healthy volunteers Protein Western blotting 2013 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1273 24058411 Homo sapiens Osteoprotegerin in exosome-like vesicles from human cultured tubular cells and urine. Urine ts chronic kidney disease patients Protein Western blotting 2013 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1274 23807490 Homo sapiens Glioma microvesicles carry selectively packaged coding and non-coding RNAs which alter gene expression in recipient cells. Glioblastoma cells cl U251 cells Protein|miRNA Mass spectrometry|Microarray 2013 Differential centrifugation Microvesicles 1275 23489476 Sus scrofa Boar seminal plasma exosomes: effect on sperm function and protein identification by sequencing. Seminal plasma ts Boar semen exosomes Protein Mass spectrometry 2013 Differential centrifugation|Gel filtration|Ultracentrifugation Exosomes 1276 23344851 Rattus norvegicus Urinary exosomes and diabetic nephropathy: a proteomic approach. Urine ts Control Protein Mass spectrometry|Western blotting 2013 Ultracentrifugation Exosomes 1277 23344851 Rattus norvegicus Urinary exosomes and diabetic nephropathy: a proteomic approach. Urine ts Diabetic Protein Mass spectrometry|Western blotting 2013 Ultracentrifugation Exosomes 1278 22437826 Drosophila melanogaster Mechanism of evenness interrupted (Evi)-exosome release at synaptic boutons. Drosophila S2 cells cl S2 cells Protein Mass spectrometry 2012 Ultracentrifugation|Density gradient centrifugation Exosomes 1279 22345510 Rattus norvegicus Characterization of membrane-shed microvesicles from cytokine-stimulated .-cells using proteomics strategies. Insulinoma cells cl NHI 6F Tu28, cytokine-stimulated Replicate 1 Protein Mass spectrometry 2012 Differential centrifugation Microparticles 1280 22345510 Rattus norvegicus Characterization of membrane-shed microvesicles from cytokine-stimulated .-cells using proteomics strategies. Insulinoma cells cl NHI 6F Tu28, cytokine-stimulated Replicate 2 Protein Mass spectrometry 2012 Differential centrifugation Microparticles 1281 22345510 Rattus norvegicus Characterization of membrane-shed microvesicles from cytokine-stimulated .-cells using proteomics strategies. Insulinoma cells cl NHI 6F Tu28, cytokine-stimulated Replicate 3 Protein Mass spectrometry 2012 Differential centrifugation Microparticles 1282 22345510 Rattus norvegicus Characterization of membrane-shed microvesicles from cytokine-stimulated .-cells using proteomics strategies. Insulinoma cells cl NHI 6F Tu28, cytokine-stimulated Replicate 1 Protein Mass spectrometry 2012 Differential centrifugation|Ultracentrifugation Exosomes 1283 22345510 Rattus norvegicus Characterization of membrane-shed microvesicles from cytokine-stimulated .-cells using proteomics strategies. Insulinoma cells cl NHI 6F Tu28, cytokine-stimulated Replicate 2 Protein Mass spectrometry 2012 Differential centrifugation|Ultracentrifugation Exosomes 1284 22345510 Rattus norvegicus Characterization of membrane-shed microvesicles from cytokine-stimulated .-cells using proteomics strategies. Insulinoma cells cl NHI 6F Tu28, cytokine-stimulated Replicate 3 Protein Mass spectrometry 2012 Differential centrifugation|Ultracentrifugation Exosomes 1285 21871517 Burkholderia pseudomallei A naturally derived outer-membrane vesicle vaccine protects against lethal pulmonary Burkholderia pseudomallei infection. Burkholderia pseudomallei ts Burkholderia pseudomallei strain 1026b Protein Mass spectrometry 2011 Differential centrifugation|Filtration|Ultracentrifugation|Density gradient centrifugation Outer membrane vesicles 1286 20880880 Homo sapiens Proinflammatory exosomes in bronchoalveolar lavage fluid of patients with sarcoidosis. Bronchoalveolar lavage fluid ts BALF - Healthy Protein Western blotting 2010 Differential centrifugation|Filtration|Ultracentrifugation|Density gradient centrifugation Exosomes 1287 20880880 Homo sapiens Proinflammatory exosomes in bronchoalveolar lavage fluid of patients with sarcoidosis. Bronchoalveolar lavage fluid ts BALF - sarcoidosis Protein Mass spectrometry|Western blotting 2010 Differential centrifugation|Filtration|Ultracentrifugation|Density gradient centrifugation Exosomes 1288 20399774 Mus musculus C2C12 myoblasts release micro-vesicles containing mtDNA and proteins involved in signal transduction. Mouse myoblast cl C2C12 Protein Mass spectrometry 2010 Differential centrifugation|Filtration|Ultracentrifugation|Density gradient centrifugation Microvesicles 1289 19912576 Homo sapiens HIV Nef is secreted in exosomes and triggers apoptosis in bystander CD4+ T cells. Cervical cancer cells cl HeLa.CIITA cells with Nef-GFP Protein Western blotting 2010 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1290 19912576 Homo sapiens HIV Nef is secreted in exosomes and triggers apoptosis in bystander CD4+ T cells. Lymphoblasts cl Jurkat cells with Nef-GFP Protein Mass spectrometry|Western blotting 2010 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1291 19912576 Homo sapiens HIV Nef is secreted in exosomes and triggers apoptosis in bystander CD4+ T cells. Lymphoblasts cl SupT1 cells with Nef-GFP Protein Mass spectrometry|Western blotting 2010 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1300 0 Saccharomyces cerevisiae Extracellular vesicles secreted by Saccharomyces cerevisiae are involved in cell wall remodelling Saccharomyces cerevisiae cl Saccharomyces cerevisiae Protein Mass spectrometry 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1301 0 Saccharomyces cerevisiae Extracellular vesicles secreted by Saccharomyces cerevisiae are involved in cell wall remodelling Saccharomyces cerevisiae cl vps2 KO - Saccharomyces cerevisiae Protein Mass spectrometry 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1302 0 Saccharomyces cerevisiae Extracellular vesicles secreted by Saccharomyces cerevisiae are involved in cell wall remodelling Saccharomyces cerevisiae cl vps23 KO - Saccharomyces cerevisiae Protein Mass spectrometry 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1303 0 Saccharomyces cerevisiae Extracellular vesicles secreted by Saccharomyces cerevisiae are involved in cell wall remodelling Saccharomyces cerevisiae cl vps36 KO - Saccharomyces cerevisiae Protein Mass spectrometry 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1304 0 Saccharomyces cerevisiae Extracellular vesicles secreted by Saccharomyces cerevisiae are involved in cell wall remodelling Saccharomyces cerevisiae cl bro1 KO - Saccharomyces cerevisiae Protein Mass spectrometry 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1305 0 Saccharomyces cerevisiae Extracellular vesicles secreted by Saccharomyces cerevisiae are involved in cell wall remodelling Saccharomyces cerevisiae cl hse1 KO - Saccharomyces cerevisiae Protein Mass spectrometry 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1306 0 Saccharomyces cerevisiae Extracellular vesicles secreted by Saccharomyces cerevisiae are involved in cell wall remodelling Saccharomyces cerevisiae cl WT control for EV subtype - Saccharomyces cerevisiae Protein Mass spectrometry 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1307 0 Saccharomyces cerevisiae Extracellular vesicles secreted by Saccharomyces cerevisiae are involved in cell wall remodelling Saccharomyces cerevisiae cl chs3 KO - Saccharomyces cerevisiae Protein Mass spectrometry 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1308 0 Saccharomyces cerevisiae Extracellular vesicles secreted by Saccharomyces cerevisiae are involved in cell wall remodelling Saccharomyces cerevisiae cl fks1 KO - Saccharomyces cerevisiae Protein Mass spectrometry 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1309 0 Saccharomyces cerevisiae Extracellular vesicles secreted by Saccharomyces cerevisiae are involved in cell wall remodelling Saccharomyces cerevisiae cl 15K H2O2 - Saccharomyces cerevisiae Protein Mass spectrometry 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1310 0 Saccharomyces cerevisiae Extracellular vesicles secreted by Saccharomyces cerevisiae are involved in cell wall remodelling Saccharomyces cerevisiae cl 15K WT - Saccharomyces cerevisiae Protein Mass spectrometry 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1311 0 Saccharomyces cerevisiae Extracellular vesicles secreted by Saccharomyces cerevisiae are involved in cell wall remodelling Saccharomyces cerevisiae cl 15K YPD - Saccharomyces cerevisiae Protein Mass spectrometry 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1312 0 Saccharomyces cerevisiae Extracellular vesicles secreted by Saccharomyces cerevisiae are involved in cell wall remodelling Saccharomyces cerevisiae cl H202 - Saccharomyces cerevisiae Protein Mass spectrometry 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1313 0 Saccharomyces cerevisiae Extracellular vesicles secreted by Saccharomyces cerevisiae are involved in cell wall remodelling Saccharomyces cerevisiae cl YPD - Saccharomyces cerevisiae Protein Mass spectrometry 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1314 0 Saccharomyces cerevisiae Extracellular vesicles secreted by Saccharomyces cerevisiae are involved in cell wall remodelling Saccharomyces cerevisiae cl yca1 KO - Saccharomyces cerevisiae Protein Mass spectrometry 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1321 33431899 Mus musculus High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance Faeces ts Intestinal epithelial cells - C57BL/6 Lipid Mass spectrometry|HPLC 2021 Differential centrifugation|Ultracentrifugation|Sucrose density gradient centrifugation Exosomes 1322 33431899 Mus musculus High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance Faeces ts Intestinal epithelial cells - C57BL/6 Lipid Mass spectrometry|HPLC 2021 Differential centrifugation|Ultracentrifugation|Sucrose density gradient centrifugation Exosomes 1323 33431899 Mus musculus High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance Faeces ts Intestinal epithelial cells - C57BL/6 Protein|Lipid|miRNA Western blotting|Mass spectrometry|Immunofluorescence|miRNA array|HPLC 2021 Differential centrifugation|Ultracentrifugation|Sucrose density gradient centrifugation Exosomes 1324 33431899 Mus musculus High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance Faeces ts Intestinal epithelial cells - C57BL/6 Protein|Lipid|miRNA Western blotting|Mass spectrometry|Immunofluorescence|miRNA array|HPLC 2021 Differential centrifugation|Ultracentrifugation|Sucrose density gradient centrifugation Exosomes 1325 33431899 Homo sapiens High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance Faeces ts Healthy volunteers Protein|Lipid Western blotting|Mass spectrometry|Immunofluorescence|HPLC 2021 Differential centrifugation|Ultracentrifugation|Sucrose density gradient centrifugation Exosomes 1326 33431899 Homo sapiens High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance Faeces ts Type 2 diabetes patients Protein|Lipid Western blotting|Mass spectrometry|Immunofluorescence|HPLC 2021 Differential centrifugation|Ultracentrifugation|Sucrose density gradient centrifugation Exosomes 1327 33431899 Mus musculus High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance Plasma ts Plasma - C57BL/6 Lipid Mass spectrometry 2021 Differential centrifugation|Ultracentrifugation|Sucrose density gradient centrifugation Exosomes 1328 33431899 Mus musculus High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance Plasma ts Plasma - C57BL/6 Lipid Mass spectrometry 2021 Differential centrifugation|Ultracentrifugation|Sucrose density gradient centrifugation Exosomes 1329 33431899 Mus musculus High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance Faeces ts Intestinal epithelial cells - C57BL/6 Lipid HPLC 2021 Differential centrifugation|Ultracentrifugation|Sucrose density gradient centrifugation Exosomes 1330 33431899 Mus musculus High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance Faeces ts Intestinal epithelial cells - C57BL/6 Lipid HPLC 2021 Differential centrifugation|Ultracentrifugation|Sucrose density gradient centrifugation Exosomes 1331 33431899 Mus musculus High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance Colorectal cancer cells cl MC38 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation|Sucrose density gradient centrifugation Exosomes 1332 33431899 Mus musculus High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance Colorectal cancer cells cl MC38 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation|Sucrose density gradient centrifugation Exosomes 1333 33368224 Homo sapiens Colorectal cancer prompted adipose tissue browning and cancer cachexia through transferring exosomal miR-146b-5p Intestinal epithelial cells cl FHs 74 Int Protein|mRNA Western blotting|RT-PCT 2020 Differential centrifugation|Ultracentrifugation Exosomes 1334 33368224 Homo sapiens Colorectal cancer prompted adipose tissue browning and cancer cachexia through transferring exosomal miR-146b-5p Colorectal cancer cells cl HCT116 Protein|mRNA Western blotting|RT-PCT 2020 Differential centrifugation|Ultracentrifugation Exosomes 1335 33199621 Mus musculus Delivery of muscle-derived exosomal miRNAs induced by HIIT improves insulin sensitivity through down-regulation of hepatic FoxO1 in mice Plasma ts Plasma - C57BL/6 Protein|miRNA Western blotting|RT-PCT 2020 Differential centrifugation|Ultracentrifugation Exosomes 1336 33199621 Mus musculus Delivery of muscle-derived exosomal miRNAs induced by HIIT improves insulin sensitivity through down-regulation of hepatic FoxO1 in mice Plasma ts Plasma - C57BL/6 Protein|miRNA Western blotting|RT-PCT 2020 Differential centrifugation|Ultracentrifugation Exosomes 1337 33199621 Mus musculus Delivery of muscle-derived exosomal miRNAs induced by HIIT improves insulin sensitivity through down-regulation of hepatic FoxO1 in mice White adipose tissue ts Epididymal white adipose tissue - C57BL/6 miRNA RT-PCR 2020 Differential centrifugation|Ultracentrifugation Exosomes 1338 33199621 Mus musculus Delivery of muscle-derived exosomal miRNAs induced by HIIT improves insulin sensitivity through down-regulation of hepatic FoxO1 in mice White adipose tissue ts Epididymal white adipose tissue - C57BL/6 miRNA RT-PCR 2020 Differential centrifugation|Ultracentrifugation Exosomes 1339 33199621 Mus musculus Delivery of muscle-derived exosomal miRNAs induced by HIIT improves insulin sensitivity through down-regulation of hepatic FoxO1 in mice Liver ts Liver - C57BL/6 miRNA RT-PCR 2020 Differential centrifugation|Ultracentrifugation Exosomes 1340 33199621 Mus musculus Delivery of muscle-derived exosomal miRNAs induced by HIIT improves insulin sensitivity through down-regulation of hepatic FoxO1 in mice Liver ts Liver - C57BL/6 miRNA RT-PCR 2020 Differential centrifugation|Ultracentrifugation Exosomes 1341 33199621 Mus musculus Delivery of muscle-derived exosomal miRNAs induced by HIIT improves insulin sensitivity through down-regulation of hepatic FoxO1 in mice Muscle ts Gastrocnemius muscle - C57BL/6 miRNA RT-PCR 2020 Differential centrifugation|Ultracentrifugation Exosomes 1342 33199621 Mus musculus Delivery of muscle-derived exosomal miRNAs induced by HIIT improves insulin sensitivity through down-regulation of hepatic FoxO1 in mice Muscle ts Gastrocnemius muscle - C57BL/6 miRNA RT-PCR 2020 Differential centrifugation|Ultracentrifugation Exosomes 1343 33159193 Rattus norvegicus Treatment of infarcted heart tissue via the capture and local delivery of circulating exosomes through antibody-conjugated magnetic nanoparticles Serum ts Serum - Sprague Dawley rats Protein Western blotting 2020 Differential centrifugation|Ultracentrifugation Exosomes 1344 33009394 Homo sapiens Platelet-derived microparticles enhance megakaryocyte differentiation and platelet generation via miR-1915-3p Platelets ts Platelets derived from umbilical cord blood Protein|miRNA Flow cytometry|Western blotting|qPCR 2020 Ficoll-Hypaque density gradient centrifugation|Differential centrifugation|Filtration Platelet-derived microparticles 1345 33009394 Mus musculus Platelet-derived microparticles enhance megakaryocyte differentiation and platelet generation via miR-1915-3p Platelets ts Platelets derived from peripheral blood - C57BL/6 Protein Flow cytometry 2020 Differential centrifugation Platelet-derived microparticles 1346 33009394 Homo sapiens Platelet-derived microparticles enhance megakaryocyte differentiation and platelet generation via miR-1915-3p Platelets ts Platelets derived from umbilical cord blood - donor 1 miRNA miRNA array 2020 Ficoll-Hypaque density gradient centrifugation|Differential centrifugation|Filtration Platelet-derived microparticles 1347 33009394 Homo sapiens Platelet-derived microparticles enhance megakaryocyte differentiation and platelet generation via miR-1915-3p Platelets ts Platelets derived from umbilical cord blood - donor 2 miRNA miRNA array 2020 Ficoll-Hypaque density gradient centrifugation|Differential centrifugation|Filtration Platelet-derived microparticles 1348 33009394 Homo sapiens Platelet-derived microparticles enhance megakaryocyte differentiation and platelet generation via miR-1915-3p Platelets ts Platelets derived from umbilical cord blood - donor 3 miRNA miRNA array 2020 Ficoll-Hypaque density gradient centrifugation|Differential centrifugation|Filtration Platelet-derived microparticles 1349 33009394 Homo sapiens Platelet-derived microparticles enhance megakaryocyte differentiation and platelet generation via miR-1915-3p Platelets ts Platelets derived from umbilical cord blood - donor 4 miRNA miRNA array 2020 Ficoll-Hypaque density gradient centrifugation|Differential centrifugation|Filtration Platelet-derived microparticles 1350 33009394 Homo sapiens Platelet-derived microparticles enhance megakaryocyte differentiation and platelet generation via miR-1915-3p Platelets ts Platelets derived from umbilical cord blood - donor 5 miRNA miRNA array 2020 Ficoll-Hypaque density gradient centrifugation|Differential centrifugation|Filtration Platelet-derived microparticles 1351 32938681 Homo sapiens Annexin A1-dependent tethering promotes extracellular vesicle aggregation revealed with single-extracellular vesicle analysis Smooth muscle cells ts Carotid artery-derived primary smooth muscle cells Protein Mass spectrometry|Western blotting 2020 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1352 32938681 Homo sapiens Annexin A1-dependent tethering promotes extracellular vesicle aggregation revealed with single-extracellular vesicle analysis Smooth muscle cells ts Carotid artery-derived primary smooth muscle cells Protein Mass spectrometry 2020 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1353 32938681 Homo sapiens Annexin A1-dependent tethering promotes extracellular vesicle aggregation revealed with single-extracellular vesicle analysis Valvular interstitial cells ts Aortic valve-derived primary valvular interstial cells Protein Mass spectrometry|Western blotting 2020 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1354 32938681 Homo sapiens Annexin A1-dependent tethering promotes extracellular vesicle aggregation revealed with single-extracellular vesicle analysis Valvular interstitial cells ts Aortic valve-derived primary valvular interstial cells Protein Mass spectrometry 2020 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1355 32438511 Homo sapiens Exosomes Derived from the Human Primary Colorectal Cancer Cell Line SW480 Orchestrate Fibroblast-Led Cancer Invasion Colorectal cancer cells cl SW480 - Fraction 6 Protein Western blotting 2020 Differential centrifugation|Filtration|OptiPrep density gradient centrifugation|Ultracentrifugation Exosomes 1356 32438511 Homo sapiens Exosomes Derived from the Human Primary Colorectal Cancer Cell Line SW480 Orchestrate Fibroblast-Led Cancer Invasion Colorectal cancer cells cl SW480 - Fraction 7 Protein Western blotting 2020 Differential centrifugation|Filtration|OptiPrep density gradient centrifugation|Ultracentrifugation Exosomes 1357 32438511 Homo sapiens Exosomes Derived from the Human Primary Colorectal Cancer Cell Line SW480 Orchestrate Fibroblast-Led Cancer Invasion Colorectal cancer cells cl SW480 - Fraction 6 Protein Western blotting 2020 Differential centrifugation|Filtration|OptiPrep density gradient centrifugation|Ultracentrifugation Exosomes 1358 32438511 Homo sapiens Exosomes Derived from the Human Primary Colorectal Cancer Cell Line SW480 Orchestrate Fibroblast-Led Cancer Invasion Colorectal cancer cells cl SW480 - Fraction 7 Protein Western blotting 2020 Differential centrifugation|Filtration|OptiPrep density gradient centrifugation|Ultracentrifugation Exosomes 1359 32132711 Homo sapiens Decoy exosomes provide protection against bacterial toxins Lung cancer cells cl A549 Protein Western blotting|Flow cytometry 2020 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1360 32132711 Homo sapiens Decoy exosomes provide protection against bacterial toxins Lung cancer cells cl A549 Protein Western blotting|Flow cytometry 2020 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1361 32132711 Homo sapiens Decoy exosomes provide protection against bacterial toxins Lung cancer cells cl A549 - 4K Pellet Protein Western blotting 2020 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1362 32132711 Homo sapiens Decoy exosomes provide protection against bacterial toxins Lung cancer cells cl A549 - 10K pellet Protein Western blotting 2020 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1363 32132711 Homo sapiens Decoy exosomes provide protection against bacterial toxins Lung cancer cells cl A549 - 100K pellet Protein Western blotting 2020 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1364 32132711 Homo sapiens Decoy exosomes provide protection against bacterial toxins Lung cancer cells cl A549 Protein Western blotting 2020 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1365 32132711 Homo sapiens Decoy exosomes provide protection against bacterial toxins Lung cancer cells cl A549 Protein Western blotting 2020 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1366 32132711 Mus musculus Decoy exosomes provide protection against bacterial toxins Plasma ts Plasma - C57BL/6 Protein Western blotting 2020 Differential centrifugation|Ultracentrifugation Exosomes 1367 32132711 Mus musculus Decoy exosomes provide protection against bacterial toxins Plasma ts Plasma - C57BL/6 Protein Western blotting|Mass spectrometry 2020 Differential centrifugation|Ultracentrifugation Exosomes 1368 32132711 Mus musculus Decoy exosomes provide protection against bacterial toxins Plasma ts Plasma - C57BL/6 Protein Western blotting|Mass spectrometry 2020 Differential centrifugation|Ultracentrifugation Exosomes 1369 33144925 Homo sapiens Triple knockdown of CDC37, HSP90-alpha and HSP90-beta diminishes extracellular vesicles-driven malignancy events and macrophage M2 polarization in oral cancer Oral cancer cells cl Ca9-22 Protein Western blotting 2020 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Total Exosome Isolation Reagent Extracellular vesicles 1370 33144925 Homo sapiens Triple knockdown of CDC37, HSP90-alpha and HSP90-beta diminishes extracellular vesicles-driven malignancy events and macrophage M2 polarization in oral cancer Oral cancer cells cl HO-1-u-1 Protein Western blotting 2020 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Total Exosome Isolation Reagent Extracellular vesicles 1371 33144925 Homo sapiens Triple knockdown of CDC37, HSP90-alpha and HSP90-beta diminishes extracellular vesicles-driven malignancy events and macrophage M2 polarization in oral cancer Oral cancer cells cl SAS Protein Western blotting 2020 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Total Exosome Isolation Reagent Extracellular vesicles 1372 33144925 Homo sapiens Triple knockdown of CDC37, HSP90-alpha and HSP90-beta diminishes extracellular vesicles-driven malignancy events and macrophage M2 polarization in oral cancer Oral cancer cells cl HSC-2 Protein Western blotting 2020 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Total Exosome Isolation Reagent Extracellular vesicles 1373 33144925 Homo sapiens Triple knockdown of CDC37, HSP90-alpha and HSP90-beta diminishes extracellular vesicles-driven malignancy events and macrophage M2 polarization in oral cancer Oral cancer cells cl HSC-4 Protein Western blotting 2020 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Total Exosome Isolation Reagent Extracellular vesicles 1374 33144925 Homo sapiens Triple knockdown of CDC37, HSP90-alpha and HSP90-beta diminishes extracellular vesicles-driven malignancy events and macrophage M2 polarization in oral cancer Oral cancer cells cl HSC-3 Protein Western blotting 2020 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Total Exosome Isolation Reagent Extracellular vesicles 1375 33144925 Homo sapiens Triple knockdown of CDC37, HSP90-alpha and HSP90-beta diminishes extracellular vesicles-driven malignancy events and macrophage M2 polarization in oral cancer Oral cancer cells cl HSC-3-M3 Protein Western blotting 2020 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Total Exosome Isolation Reagent Extracellular vesicles 1376 33144925 Homo sapiens Triple knockdown of CDC37, HSP90-alpha and HSP90-beta diminishes extracellular vesicles-driven malignancy events and macrophage M2 polarization in oral cancer Oral cancer cells cl HSC-3-M3 Protein Western blotting 2020 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Total Exosome Isolation Reagent Extracellular vesicles 1377 33144925 Homo sapiens Triple knockdown of CDC37, HSP90-alpha and HSP90-beta diminishes extracellular vesicles-driven malignancy events and macrophage M2 polarization in oral cancer Oral cancer cells cl HSC-3-M3 Protein Western blotting 2020 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Total Exosome Isolation Reagent Extracellular vesicles 1378 33144925 Homo sapiens Triple knockdown of CDC37, HSP90-alpha and HSP90-beta diminishes extracellular vesicles-driven malignancy events and macrophage M2 polarization in oral cancer Oral epithelial cells cl RT-7 Protein Western blotting 2020 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Total Exosome Isolation Reagent Extracellular vesicles 1379 33135636 Mus musculus CD14 release induced by P2X7 receptor restricts inflammation and increases survival during sepsis Macrophage ts Bone marrow-derived macrophages - WT C57BL/6 Protein ELISA 2020 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1380 33135636 Mus musculus CD14 release induced by P2X7 receptor restricts inflammation and increases survival during sepsis Macrophage ts Bone marrow-derived macrophages - WT C57BL/6 Protein Western blotting 2020 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1381 33135636 Mus musculus CD14 release induced by P2X7 receptor restricts inflammation and increases survival during sepsis Macrophage ts Bone marrow-derived macrophages - WT C57BL/6 Protein ELISA 2020 Differential centrifugation|ExoQuick Kit Extracellular vesicles 1382 33135636 Mus musculus CD14 release induced by P2X7 receptor restricts inflammation and increases survival during sepsis Macrophage ts Bone marrow-derived macrophages - WT C57BL/6 Protein ELISA 2020 Differential centrifugation|ExoQuick Kit Extracellular vesicles 1383 33135636 Mus musculus CD14 release induced by P2X7 receptor restricts inflammation and increases survival during sepsis Macrophage ts Bone marrow-derived macrophages - WT C57BL/6 Protein ELISA 2020 Differential centrifugation|ExoQuick Kit Extracellular vesicles 1384 33135636 Mus musculus CD14 release induced by P2X7 receptor restricts inflammation and increases survival during sepsis Macrophage ts Bone marrow-derived macrophages - P2rx7-/- C57BL/6 Protein ELISA 2020 Differential centrifugation|ExoQuick Kit Extracellular vesicles 1385 33135636 Mus musculus CD14 release induced by P2X7 receptor restricts inflammation and increases survival during sepsis Macrophage ts Bone marrow-derived macrophages - P2rx7-/- C57BL/6 Protein ELISA 2020 Differential centrifugation|ExoQuick Kit Extracellular vesicles 1386 33135636 Mus musculus CD14 release induced by P2X7 receptor restricts inflammation and increases survival during sepsis Macrophage ts Bone marrow-derived macrophages - P2rx7-/- C57BL/6 Protein ELISA 2020 Differential centrifugation|ExoQuick Kit Extracellular vesicles 1387 33135636 Mus musculus CD14 release induced by P2X7 receptor restricts inflammation and increases survival during sepsis Macrophage ts Bone marrow-derived macrophages - WT C57BL/6 Protein Western blotting 2020 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1388 33135636 Mus musculus CD14 release induced by P2X7 receptor restricts inflammation and increases survival during sepsis Macrophage ts Bone marrow-derived macrophages - WT C57BL/6 Protein Western blotting 2020 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1389 33135636 Mus musculus CD14 release induced by P2X7 receptor restricts inflammation and increases survival during sepsis Macrophage ts Bone marrow-derived macrophages - Casp1/11-/- C57BL/6 Protein Western blotting 2020 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1390 33135636 Mus musculus CD14 release induced by P2X7 receptor restricts inflammation and increases survival during sepsis Macrophage ts Bone marrow-derived macrophages - Nlrp3-/- C57BL/6 Protein Western blotting 2020 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1391 32939236 Homo sapiens Salivary extracellular vesicles inhibit Zika virus but not SARS-CoV-2 infection Saliva ts Saliva - pooled Protein Western blotting 2020 Centrifugation|Filtration|Centrifugal ultrafiltration Extracellular vesicles 1392 32939236 Homo sapiens Salivary extracellular vesicles inhibit Zika virus but not SARS-CoV-2 infection Saliva ts Saliva - pooled (13.1 µg protein) Protein Western blotting 2020 Differential centrifugation|Tangential flow filtration|Size exclusion chromatography Extracellular vesicles 1393 32939236 Homo sapiens Salivary extracellular vesicles inhibit Zika virus but not SARS-CoV-2 infection Saliva ts Saliva - pooled (7.1 µg protein) Protein Western blotting 2020 Differential centrifugation|Tangential flow filtration|Size exclusion chromatography Extracellular vesicles 1394 32939236 Homo sapiens Salivary extracellular vesicles inhibit Zika virus but not SARS-CoV-2 infection Saliva ts Saliva - pooled (CD9, CD63, and CD81-positive EVs) Protein|Lipid Flow cytometry 2020 Differential centrifugation|Tangential flow filtration|Size exclusion chromatography Extracellular vesicles 1395 32939236 Homo sapiens Salivary extracellular vesicles inhibit Zika virus but not SARS-CoV-2 infection Saliva ts Saliva - pooled (CD9-positive EVs) Protein|Lipid Flow cytometry 2020 Differential centrifugation|Tangential flow filtration|Size exclusion chromatography Extracellular vesicles 1396 32939236 Homo sapiens Salivary extracellular vesicles inhibit Zika virus but not SARS-CoV-2 infection Saliva ts Saliva - pooled (CD63-positive EVs) Protein|Lipid Flow cytometry 2020 Differential centrifugation|Tangential flow filtration|Size exclusion chromatography Extracellular vesicles 1397 32939236 Homo sapiens Salivary extracellular vesicles inhibit Zika virus but not SARS-CoV-2 infection Saliva ts Saliva - pooled (CD81-positive EVs) Protein|Lipid Flow cytometry 2020 Differential centrifugation|Tangential flow filtration|Size exclusion chromatography Extracellular vesicles 1398 35165262 Homo sapiens DNAJB8 in small extracellular vesicles promotes Oxaliplatin resistance through TP53/MDR1 pathway in colon cancer Colon cancer cells cl SW480 Protein Western blotting 2022 Differential centrifugation|Tangential flow filtration|Ultracentrifugation Extracellular vesicles 1399 35165262 Homo sapiens DNAJB8 in small extracellular vesicles promotes Oxaliplatin resistance through TP53/MDR1 pathway in colon cancer Colon cancer cells cl SW480 - Oxaliplatin-resistant Protein Western blotting 2022 Differential centrifugation|Tangential flow filtration|Ultracentrifugation Extracellular vesicles 1400 35165262 Homo sapiens DNAJB8 in small extracellular vesicles promotes Oxaliplatin resistance through TP53/MDR1 pathway in colon cancer Colon cancer cells cl SW620 Protein Western blotting 2022 Differential centrifugation|Tangential flow filtration|Ultracentrifugation Extracellular vesicles 1401 35165262 Homo sapiens DNAJB8 in small extracellular vesicles promotes Oxaliplatin resistance through TP53/MDR1 pathway in colon cancer Colon cancer cells cl SW620 - Oxaliplatin-resistant Protein Western blotting 2022 Differential centrifugation|Tangential flow filtration|Ultracentrifugation Extracellular vesicles 1402 35165262 Homo sapiens DNAJB8 in small extracellular vesicles promotes Oxaliplatin resistance through TP53/MDR1 pathway in colon cancer Colon cancer cells cl COAD - Fraction 4 Protein Western blotting 2022 Differential centrifugation|Tangential flow filtration|Ultracentrifugation|OptiPrep density gradient centrifugation Extracellular vesicles 1403 35165262 Homo sapiens DNAJB8 in small extracellular vesicles promotes Oxaliplatin resistance through TP53/MDR1 pathway in colon cancer Colon cancer cells cl COAD - Fraction 5 Protein Western blotting 2022 Differential centrifugation|Tangential flow filtration|Ultracentrifugation|OptiPrep density gradient centrifugation Extracellular vesicles 1404 35165262 Homo sapiens DNAJB8 in small extracellular vesicles promotes Oxaliplatin resistance through TP53/MDR1 pathway in colon cancer Colon cancer cells cl COAD - Fraction 6 Protein Western blotting 2022 Differential centrifugation|Tangential flow filtration|Ultracentrifugation|OptiPrep density gradient centrifugation Extracellular vesicles 1405 35165262 Homo sapiens DNAJB8 in small extracellular vesicles promotes Oxaliplatin resistance through TP53/MDR1 pathway in colon cancer Colon cancer cells cl COAD - Fraction 7 Protein Western blotting 2022 Differential centrifugation|Tangential flow filtration|Ultracentrifugation|OptiPrep density gradient centrifugation Extracellular vesicles 1406 35165262 Homo sapiens DNAJB8 in small extracellular vesicles promotes Oxaliplatin resistance through TP53/MDR1 pathway in colon cancer Colon cancer cells cl COAD - Fraction 8 Protein Western blotting 2022 Differential centrifugation|Tangential flow filtration|Ultracentrifugation|OptiPrep density gradient centrifugation Extracellular vesicles 1407 35165262 Homo sapiens DNAJB8 in small extracellular vesicles promotes Oxaliplatin resistance through TP53/MDR1 pathway in colon cancer Colon cancer cells cl COAD - Fraction 9 Protein Western blotting 2022 Differential centrifugation|Tangential flow filtration|Ultracentrifugation|OptiPrep density gradient centrifugation Extracellular vesicles 1408 36706192 Homo sapiens Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles Embryonic kidney cells cl HEK293T Protein Western blotting|Mass spectrometry 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1409 36706192 Homo sapiens Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles Embryonic kidney cells cl HEK293T Protein Western blotting 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1410 36706192 Homo sapiens Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles Embryonic kidney cells cl HEK293T Protein Western blotting 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1411 36706192 Homo sapiens Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles Embryonic kidney cells cl HEK293T Protein Western blotting 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1412 36706192 Homo sapiens Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles Embryonic kidney cells cl HEK293T - Fraction 4 Protein Western blotting 2023 Differential centrifugation|Filtration|Ultracentrifugation|OptiPrep density gradient centrifugation Extracellular vesicles 1413 36706192 Homo sapiens Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles Embryonic kidney cells cl HEK293T - Fraction 5 Protein Western blotting|Mass spectrometry 2023 Differential centrifugation|Filtration|Ultracentrifugation|OptiPrep density gradient centrifugation Extracellular vesicles 1414 36706192 Homo sapiens Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles Embryonic kidney cells cl HEK293T - Fraction 6 Protein Western blotting 2023 Differential centrifugation|Filtration|Ultracentrifugation|OptiPrep density gradient centrifugation Extracellular vesicles 1415 36706192 Homo sapiens Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles Embryonic kidney cells cl HEK293T Protein Western blotting 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1416 36706192 Homo sapiens Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles Embryonic kidney cells cl HEK293T Protein Western blotting 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1417 36706192 Homo sapiens Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles Embryonic kidney cells cl HEK293T Protein Western blotting 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1418 36706192 Homo sapiens Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles Embryonic kidney cells cl HEK293T Protein Western blotting 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1419 36706192 Homo sapiens Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles Embryonic kidney cells cl HEK293T Protein Western blotting 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1420 36706192 Homo sapiens Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles Embryonic kidney cells cl HEK293T - Clone 1 Protein Western blotting 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1421 36706192 Homo sapiens Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles Embryonic kidney cells cl HEK293T - Clone 2 Protein Western blotting 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1422 36706192 Homo sapiens Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles Embryonic kidney cells cl HEK293T Protein Western blotting 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1423 36706192 Homo sapiens Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles Embryonic kidney cells cl HEK293T Protein Western blotting 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1424 36706192 Homo sapiens Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles Embryonic kidney cells cl HEK293T Protein Western blotting 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1425 36706192 Homo sapiens Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles Embryonic kidney cells cl HEK293T Protein Western blotting 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1426 36706192 Homo sapiens Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles Embryonic kidney cells cl HEK293T Protein Western blotting 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1427 36706192 Homo sapiens Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles Embryonic kidney cells cl HEK293T - Fraction 5 Protein Western blotting 2023 Differential centrifugation|Filtration|Ultracentrifugation|OptiPrep density gradient centrifugation Extracellular vesicles 1428 36706192 Homo sapiens Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles Embryonic kidney cells cl HEK293T - Fraction 6 Protein Western blotting 2023 Differential centrifugation|Filtration|Ultracentrifugation|OptiPrep density gradient centrifugation Extracellular vesicles 1429 36706192 Homo sapiens Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles Embryonic kidney cells cl HEK293T - Fraction 5 Protein Western blotting 2023 Differential centrifugation|Filtration|Ultracentrifugation|OptiPrep density gradient centrifugation Extracellular vesicles 1430 36706192 Homo sapiens Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles Embryonic kidney cells cl HEK293T - Fraction 6 Protein Western blotting 2023 Differential centrifugation|Filtration|Ultracentrifugation|OptiPrep density gradient centrifugation Extracellular vesicles 1431 36706192 Homo sapiens Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles Embryonic kidney cells cl HEK293T Protein Western blotting 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1432 29472616 Homo sapiens Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 Colorectal cancer cells cl HCT116 Protein Mass spectrometry|Western blotting 2018 Differential centrifugation|Ultracentrifugation Exosomes 1433 29472616 Homo sapiens Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 Colorectal cancer cells cl HCT116 Protein Mass spectrometry|Western blotting 2018 Differential centrifugation|Ultracentrifugation Exosomes 1434 29472616 Homo sapiens Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 Colorectal cancer cells cl HCT116 Protein Western blotting 2018 Differential centrifugation|Ultracentrifugation Exosomes 1435 29472616 Homo sapiens Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 Colorectal cancer cells cl HCT116 Protein|miRNA Western blotting|miR-chip array 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1436 29472616 Homo sapiens Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 Colorectal cancer cells cl HCT116 Protein|miRNA Western blotting|miR-chip array 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1437 29472616 Homo sapiens Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 Colorectal cancer cells cl HCT116 Protein|miRNA Western blotting|miR-chip array 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1438 29472616 Homo sapiens Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 Colorectal cancer cells cl HT29 Protein|miRNA Mass spectrometry|miR-chip array 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1439 29472616 Homo sapiens Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 Colorectal cancer cells cl HT29 Protein|miRNA Mass spectrometry|miR-chip array 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1440 29472616 Homo sapiens Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 Colorectal cancer cells cl HCT116 - Fraction 5 Protein|miRNA Western blotting|qPCR 2018 Differential centrifugation|Filtration|Ultracentrifugation|OptiPrep density gradient centrifugation Exosomes 1441 29472616 Homo sapiens Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 Colorectal cancer cells cl HCT116 - Fraction 6 Protein|miRNA Western blotting|qPCR 2018 Differential centrifugation|Filtration|Ultracentrifugation|OptiPrep density gradient centrifugation Exosomes 1442 29472616 Homo sapiens Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 Colorectal cancer cells cl HCT116 - Fraction 7 Protein|miRNA Western blotting|qPCR 2018 Differential centrifugation|Filtration|Ultracentrifugation|OptiPrep density gradient centrifugation Exosomes 1443 29472616 Homo sapiens Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 Colorectal cancer cells cl HCT116 - Fraction 8 miRNA qPCR 2018 Differential centrifugation|Filtration|Ultracentrifugation|OptiPrep density gradient centrifugation Exosomes 1444 29472616 Homo sapiens Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 Colorectal cancer cells cl HCT116 - Fraction 5 miRNA qPCR 2018 Differential centrifugation|Filtration|Ultracentrifugation|OptiPrep density gradient centrifugation Exosomes 1445 29472616 Homo sapiens Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 Colorectal cancer cells cl HCT116 - Fraction 6 miRNA qPCR 2018 Differential centrifugation|Filtration|Ultracentrifugation|OptiPrep density gradient centrifugation Exosomes 1446 29472616 Homo sapiens Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 Colorectal cancer cells cl HCT116 - Fraction 7 miRNA qPCR 2018 Differential centrifugation|Filtration|Ultracentrifugation|OptiPrep density gradient centrifugation Exosomes 1447 29472616 Homo sapiens Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 Colorectal cancer cells cl HCT116 - Fraction 8 miRNA qPCR 2018 Differential centrifugation|Filtration|Ultracentrifugation|OptiPrep density gradient centrifugation Exosomes 1448 29472616 Homo sapiens Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 Plasma ts Plasma miRNA qPCR 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1449 29472616 Homo sapiens Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 Plasma ts Plasma miRNA qPCR 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1450 31949130 Homo sapiens circRNA-002178 act as a ceRNA to promote PDL1/PD1 expression in lung adenocarcinoma Serum ts Healthy volunteers circRNA qRT-PCR 2020 Total Exosome Isolation Kit Exosomes 1451 31949130 Homo sapiens circRNA-002178 act as a ceRNA to promote PDL1/PD1 expression in lung adenocarcinoma Serum ts Lung adenocarcinoma patients circRNA qRT-PCR 2020 Total Exosome Isolation Kit Exosomes 1452 31949130 Homo sapiens circRNA-002178 act as a ceRNA to promote PDL1/PD1 expression in lung adenocarcinoma Lung epithelial cells cl BEAS-2B circRNA qRT-PCR 2020 Total Exosome Isolation Reagent Exosomes 1453 31949130 Homo sapiens circRNA-002178 act as a ceRNA to promote PDL1/PD1 expression in lung adenocarcinoma Lung cancer cells cl A549 circRNA qRT-PCR 2020 Total Exosome Isolation Reagent Exosomes 1454 31949130 Homo sapiens circRNA-002178 act as a ceRNA to promote PDL1/PD1 expression in lung adenocarcinoma Lung cancer cells cl PC9 circRNA qRT-PCR 2020 Total Exosome Isolation Reagent Exosomes 1455 31949130 Homo sapiens circRNA-002178 act as a ceRNA to promote PDL1/PD1 expression in lung adenocarcinoma Lung cancer cells cl 95D circRNA qRT-PCR 2020 Total Exosome Isolation Reagent Exosomes 1456 31969559 Homo sapiens Exosome-transmitted miR-567 reverses trastuzumab resistance by inhibiting ATG5 in breast cancer Breast cancer cells cl SKBR-3 Protein|miRNA Western blotting|qRT-PCR 2020 Differential centrifugation||Filtration|Ultracentrifugation Exosomes 1457 31969559 Homo sapiens Exosome-transmitted miR-567 reverses trastuzumab resistance by inhibiting ATG5 in breast cancer Breast cancer cells cl BT474 Protein|miRNA Western blotting|qRT-PCR 2020 Differential centrifugation||Filtration|Ultracentrifugation Exosomes 1458 31969559 Homo sapiens Exosome-transmitted miR-567 reverses trastuzumab resistance by inhibiting ATG5 in breast cancer Mammary epithelial cells cl MCF-10A miRNA qRT-PCR 2020 Differential centrifugation||Filtration|Ultracentrifugation Exosomes 1459 31969559 Homo sapiens Exosome-transmitted miR-567 reverses trastuzumab resistance by inhibiting ATG5 in breast cancer Breast cancer cells cl MCF-7 miRNA qRT-PCR 2020 Differential centrifugation||Filtration|Ultracentrifugation Exosomes 1460 31969559 Homo sapiens Exosome-transmitted miR-567 reverses trastuzumab resistance by inhibiting ATG5 in breast cancer Breast cancer cells cl MDA-MB-231 miRNA qRT-PCR 2020 Differential centrifugation||Filtration|Ultracentrifugation Exosomes 1461 31969559 Homo sapiens Exosome-transmitted miR-567 reverses trastuzumab resistance by inhibiting ATG5 in breast cancer Breast cancer cells cl MDA-MB-453 miRNA qRT-PCR 2020 Differential centrifugation||Filtration|Ultracentrifugation Exosomes 1462 31969559 Homo sapiens Exosome-transmitted miR-567 reverses trastuzumab resistance by inhibiting ATG5 in breast cancer Breast cancer cells cl SKBR-3 miRNA qRT-PCR 2020 Differential centrifugation||Filtration|Ultracentrifugation Exosomes 1463 31969559 Homo sapiens Exosome-transmitted miR-567 reverses trastuzumab resistance by inhibiting ATG5 in breast cancer Breast cancer cells cl BT474 miRNA qRT-PCR 2020 Differential centrifugation||Filtration|Ultracentrifugation Exosomes 1464 35054579 Gallus gallus Characterization of the Role of Extracellular Vesicles Released from Chicken Tracheal Cells in the Antiviral Responses against Avian Influenza Virus Trachea ts SPF chicken embryo trachea Protein Mass spectrometry 2021 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1465 35054579 Gallus gallus Characterization of the Role of Extracellular Vesicles Released from Chicken Tracheal Cells in the Antiviral Responses against Avian Influenza Virus Trachea ts SPF chicken embryo trachea Protein Mass spectrometry 2021 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1466 35054579 Gallus gallus Characterization of the Role of Extracellular Vesicles Released from Chicken Tracheal Cells in the Antiviral Responses against Avian Influenza Virus Trachea ts SPF chicken embryo trachea Protein Mass spectrometry 2021 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1467 32132543 Homo sapiens Therapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension Pulmonary artery endothelial cells cl HPAEC Protein Western blotting 2020 miRCURY Exosome Isolation Kit|Centrifugation|Sonication Exosomes 1468 32132543 Homo sapiens Therapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension Pulmonary artery endothelial cells cl HPAEC miRNA RT-PCR 2020 miRCURY Exosome Isolation Kit|Centrifugation|Sonication Exosomes 1469 32132543 Homo sapiens Therapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension Pulmonary artery endothelial cells cl HPAEC miRNA RT-PCR 2020 miRCURY Exosome Isolation Kit|Centrifugation|Sonication Exosomes 1470 32024826 Mus musculus Liver governs adipose remodelling via extracellular vesicles in response to lipid overload Hepatocytes ts Primary hepatocytes - C57BL/6 Protein Western blotting 2020 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1471 32024826 Mus musculus Liver governs adipose remodelling via extracellular vesicles in response to lipid overload Hepatocytes ts Primary hepatocytes - C57BL/6 Protein Western blotting 2020 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1472 32024826 Mus musculus Liver governs adipose remodelling via extracellular vesicles in response to lipid overload Hepatocytes ts Primary hepatocytes - C57BL/6 - Fraction 2 Protein Western blotting 2020 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Ultracentrifugation|Sucrose density gradient centrifugation Extracellular vesicles 1473 32024826 Mus musculus Liver governs adipose remodelling via extracellular vesicles in response to lipid overload Hepatocytes ts Primary hepatocytes - C57BL/6 - Fraction 3 Protein Western blotting 2020 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Ultracentrifugation|Sucrose density gradient centrifugation Extracellular vesicles 1474 32024826 Mus musculus Liver governs adipose remodelling via extracellular vesicles in response to lipid overload Hepatocytes ts Primary hepatocytes - C57BL/6 - Fraction 4 Protein Western blotting 2020 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Ultracentrifugation|Sucrose density gradient centrifugation Extracellular vesicles 1475 32024826 Mus musculus Liver governs adipose remodelling via extracellular vesicles in response to lipid overload Hepatocytes ts Primary hepatocytes - C57BL/6 - Fraction 5 Protein Western blotting 2020 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Ultracentrifugation|Sucrose density gradient centrifugation Extracellular vesicles 1476 32024826 Mus musculus Liver governs adipose remodelling via extracellular vesicles in response to lipid overload Serum ts Serum - C57BL/6 miRNA miRNA array 2020 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1477 32024826 Mus musculus Liver governs adipose remodelling via extracellular vesicles in response to lipid overload Serum ts Serum - C57BL/6 miRNA miRNA array 2020 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1478 32024826 Mus musculus Liver governs adipose remodelling via extracellular vesicles in response to lipid overload Serum ts Serum - C57BL/6 miRNA miRNA array 2020 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1479 32024826 Mus musculus Liver governs adipose remodelling via extracellular vesicles in response to lipid overload Serum ts Serum - C57BL/6 miRNA miRNA array 2020 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1480 32024826 Mus musculus Liver governs adipose remodelling via extracellular vesicles in response to lipid overload Hepatocytes ts Primary hepatocytes - WT C57BL/6 Protein|miRNA Western blotting|miRNA array 2020 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1481 32024826 Mus musculus Liver governs adipose remodelling via extracellular vesicles in response to lipid overload Hepatocytes ts Primary hepatocytes - Liver-specific Ggpps-/- C57BL/6 Protein|miRNA Western blotting|miRNA array 2020 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1482 32024826 Mus musculus Liver governs adipose remodelling via extracellular vesicles in response to lipid overload Hepatocytes ts Primary hepatocytes - WT C57BL/6 Protein|miRNA Western blotting|miRNA array 2020 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1483 32024826 Mus musculus Liver governs adipose remodelling via extracellular vesicles in response to lipid overload Hepatocytes ts Primary hepatocytes - Liver-specific Ggpps-/- C57BL/6 Protein|miRNA Western blotting|miRNA array 2020 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1484 32024826 Mus musculus Liver governs adipose remodelling via extracellular vesicles in response to lipid overload Hepatocytes ts Primary hepatocytes - C57BL/6 Protein Western blotting 2020 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1485 32024826 Mus musculus Liver governs adipose remodelling via extracellular vesicles in response to lipid overload Hepatocytes ts Primary hepatocytes - C57BL/7 Protein Western blotting 2020 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1486 32024826 Mus musculus Liver governs adipose remodelling via extracellular vesicles in response to lipid overload Hepatocytes ts Primary hepatocytes - C57BL/8 Protein Western blotting 2020 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1487 32024826 Mus musculus Liver governs adipose remodelling via extracellular vesicles in response to lipid overload Hepatocytes ts Primary hepatocytes - C57BL/9 Protein Western blotting 2020 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1488 32024826 Mus musculus Liver governs adipose remodelling via extracellular vesicles in response to lipid overload Plasma ts Plasma - C57BL/6 miRNA qPCR 2020 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1489 32024826 Mus musculus Liver governs adipose remodelling via extracellular vesicles in response to lipid overload Plasma ts Plasma - C57BL/6 miRNA qPCR 2020 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1490 32024826 Homo sapiens Liver governs adipose remodelling via extracellular vesicles in response to lipid overload Plasma ts Steatosis patients (male) with BMI 20-50 kg/m2 miRNA qPCR 2020 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1491 32024826 Homo sapiens Liver governs adipose remodelling via extracellular vesicles in response to lipid overload Plasma ts Non-alcoholic fatty liver disease patients with BMI <30 kg/m2 miRNA qPCR 2020 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1492 32024826 Homo sapiens Liver governs adipose remodelling via extracellular vesicles in response to lipid overload Plasma ts Non-alcoholic fatty liver disease patients with BMI >30 kg/m2 miRNA qPCR 2020 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1493 33991177 Homo sapiens Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells Gastric cancer cells cl MKN1 - 100K pellet Protein Western blotting|Mass spectrometry 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 1494 33991177 Homo sapiens Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells Gastric cancer cells cl MKN1 - 100K pellet Protein Western blotting|Mass spectrometry 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 1495 33991177 Homo sapiens Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells Gastric cancer cells cl MKN1 - 100K pellet Protein Western blotting|Mass spectrometry 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 1496 33991177 Homo sapiens Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells Gastric cancer cells cl MKN1 - 10K pellet Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Large extracellular vesicles 1497 33991177 Homo sapiens Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells Gastric cancer cells cl MKN1 - 10K pellet Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Large extracellular vesicles 1498 33991177 Homo sapiens Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells Gastric cancer cells cl MKN1 - 10K pellet Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Large extracellular vesicles 1499 33982667 Homo sapiens Exosomal circRNA 0001445 promotes glioma progression through miRNA-127-5p/SNX5 pathway Glioblastoma cells cl A172 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Exosomes 1500 33982667 Homo sapiens Exosomal circRNA 0001445 promotes glioma progression through miRNA-127-5p/SNX5 pathway Glioblastoma cells cl U373 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Exosomes 1501 33953168 Homo sapiens Mastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation Serum ts Healthy volunteers Protein|miRNA Western blotting|qRT-PCR 2021 ExoQuick Kit Extracellular vesicles 1502 33953168 Homo sapiens Mastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation Serum ts Systemic mastocytosis patients - Tryptase <110 ng/mL Protein|miRNA Western blotting|qRT-PCR 2021 ExoQuick Kit Extracellular vesicles 1503 33953168 Homo sapiens Mastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation Serum ts Systemic mastocytosis patients - Tryptase >110 ng/mL Protein|miRNA Western blotting|qRT-PCR 2021 ExoQuick Kit Extracellular vesicles 1504 33953168 Homo sapiens Mastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation Serum ts Healthy volunteers - Pooled Protein Western blotting 2021 Centrifugation|Filtration|Iodixanol density gradient centrifugation|Ultracentrifugation Extracellular vesicles 1505 33953168 Homo sapiens Mastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation Serum ts Systemic mastocytosis patients - Tryptase <110 ng/mL - Pooled Protein Western blotting 2021 Centrifugation|Filtration|Iodixanol density gradient centrifugation|Ultracentrifugation Extracellular vesicles 1506 33953168 Homo sapiens Mastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation Serum ts Systemic mastocytosis patients - Tryptase >110 ng/mL - Pooled Protein Western blotting 2021 Centrifugation|Filtration|Iodixanol density gradient centrifugation|Ultracentrifugation Extracellular vesicles 1507 33953168 Homo sapiens Mastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation Serum ts Systemic mastocytosis patients - Fraction 1 Protein Western blotting 2021 Centrifugation|Filtration|Iodixanol density gradient centrifugation|Ultracentrifugation Extracellular vesicles 1508 33953168 Homo sapiens Mastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation Serum ts Systemic mastocytosis patients - Fraction 2 Protein Western blotting 2021 Centrifugation|Filtration|Iodixanol density gradient centrifugation|Ultracentrifugation Extracellular vesicles 1509 33953168 Homo sapiens Mastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation Serum ts Systemic mastocytosis patients - Fraction 3 Protein Western blotting 2021 Centrifugation|Filtration|Iodixanol density gradient centrifugation|Ultracentrifugation Extracellular vesicles 1510 33953168 Homo sapiens Mastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation Serum ts Systemic mastocytosis patients - Fraction 4 Protein Western blotting 2021 Centrifugation|Filtration|Iodixanol density gradient centrifugation|Ultracentrifugation Extracellular vesicles 1511 33953168 Homo sapiens Mastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation Serum ts Systemic mastocytosis patients - Fraction 5 Protein Western blotting 2021 Centrifugation|Filtration|Iodixanol density gradient centrifugation|Ultracentrifugation Extracellular vesicles 1512 33953168 Homo sapiens Mastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation Serum ts Systemic mastocytosis patients - Fraction 6 Protein Western blotting 2021 Centrifugation|Filtration|Iodixanol density gradient centrifugation|Ultracentrifugation Extracellular vesicles 1513 33953168 Homo sapiens Mastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation Serum ts Systemic mastocytosis patients with osteoporosis/osteopenia miRNA qRT-PCR 2021 ExoQuick Kit Extracellular vesicles 1514 33953168 Homo sapiens Mastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation Serum ts Systemic mastocytosis patients without osteoporosis/osteopenia miRNA qRT-PCR 2021 ExoQuick Kit Extracellular vesicles 1515 33953168 Homo sapiens Mastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation Serum ts Systemic mastocytosis (male) patients with osteoporosis/osteopenia miRNA qRT-PCR 2021 ExoQuick Kit Extracellular vesicles 1516 33953168 Homo sapiens Mastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation Serum ts Systemic mastocytosis (female) patients with osteoporosis/osteopenia miRNA qRT-PCR 2021 ExoQuick Kit Extracellular vesicles 1517 33953168 Homo sapiens Mastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation Serum ts Systemic mastocytosis patients with osteoporosis/osteopenia - Indolent miRNA qRT-PCR 2021 ExoQuick Kit Extracellular vesicles 1518 33953168 Homo sapiens Mastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation Serum ts Systemic mastocytosis patients with osteoporosis/osteopenia - Smoldering miRNA qRT-PCR 2021 ExoQuick Kit Extracellular vesicles 1519 33953168 Homo sapiens Mastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation Mast cells cl HMC-1.1 miRNA qRT-PCR 2021 ExoQuick Kit Extracellular vesicles 1520 33953168 Homo sapiens Mastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation Mast cells cl HMC-1.2 miRNA qRT-PCR 2021 ExoQuick Kit Extracellular vesicles 1521 33953168 Homo sapiens Mastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation Embryonic kidney cells cl HEK293 miRNA qRT-PCR 2021 ExoQuick Kit Extracellular vesicles 1522 33911067 Homo sapiens Tumor-derived exosomal circPSMA1 facilitates the tumorigenesis, metastasis, and migration in triple-negative breast cancer (TNBC) through miR-637/Akt1/β-catenin (cyclin D1) axis Breast cancer cells cl MDA-MB-231 circRNAs RNA sequencing 2021 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1523 33911067 Homo sapiens Tumor-derived exosomal circPSMA1 facilitates the tumorigenesis, metastasis, and migration in triple-negative breast cancer (TNBC) through miR-637/Akt1/β-catenin (cyclin D1) axis Breast cancer cells cl MCF7 circRNAs RNA sequencing 2021 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1524 33911067 Homo sapiens Tumor-derived exosomal circPSMA1 facilitates the tumorigenesis, metastasis, and migration in triple-negative breast cancer (TNBC) through miR-637/Akt1/β-catenin (cyclin D1) axis Serum ts Non-TNBC patients circRNAs qRT-PCR 2021 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1525 33911067 Homo sapiens Tumor-derived exosomal circPSMA1 facilitates the tumorigenesis, metastasis, and migration in triple-negative breast cancer (TNBC) through miR-637/Akt1/β-catenin (cyclin D1) axis Serum ts TNBC patients circRNAs qRT-PCR 2021 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1526 33479185 Homo sapiens Human umbilical cord mesenchymal stem cell-derived exosomal miR-146a-5p reduces microglial-mediated neuroinflammation via suppression of the IRAK1/TRAF6 signaling pathway after ischemic stroke Mesenchymal stem cells cl hUMSCs Protein|miRNA Western blotting|Microarray 2021 Differential centrifugation|Ultracentrifugation Exosomes 1527 33752173 Homo sapiens Exosomal miR-222 from adriamycin-resistant MCF-7 breast cancer cells promote macrophages M2 polarization via PTEN/Akt to induce tumor progression Breast cancer cells cl MCF7 - Adriamycin-resistant miRNA RT-PCR 2021 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1528 33752173 Homo sapiens Exosomal miR-222 from adriamycin-resistant MCF-7 breast cancer cells promote macrophages M2 polarization via PTEN/Akt to induce tumor progression Breast cancer cells cl MCF7 - Adriamycin-sensitive miRNA RT-PCR 2021 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1529 33752173 Homo sapiens Exosomal miR-222 from adriamycin-resistant MCF-7 breast cancer cells promote macrophages M2 polarization via PTEN/Akt to induce tumor progression Breast cancer cells ts Breast cancer tissue from patients - chemoresistant miRNA RT-PCR 2021 Total Exosome Isolation Kit|Centrifugation Exosomes 1530 33752173 Homo sapiens Exosomal miR-222 from adriamycin-resistant MCF-7 breast cancer cells promote macrophages M2 polarization via PTEN/Akt to induce tumor progression Breast cancer cells ts Brease cancer tissue from - chemosensitive miRNA RT-PCR 2021 Total Exosome Isolation Kit|Centrifugation Exosomes 1531 33752173 Homo sapiens Exosomal miR-222 from adriamycin-resistant MCF-7 breast cancer cells promote macrophages M2 polarization via PTEN/Akt to induce tumor progression Plasma ts Breast cancer patients - chemoresistant miRNA RT-PCR 2021 Total Exosome Isolation Kit|Centrifugation Exosomes 1532 33752173 Homo sapiens Exosomal miR-222 from adriamycin-resistant MCF-7 breast cancer cells promote macrophages M2 polarization via PTEN/Akt to induce tumor progression Plasma ts Breast cancer patients - chemosensitive miRNA RT-PCR 2021 Total Exosome Isolation Kit|Centrifugation Exosomes 1533 33589572 Homo sapiens Exosomal long non-coding RNA LINC00662 promotes non-small cell lung cancer progression by miR-320d/E2F1 axis Plasma ts Non-small cell lung cancer Protein|lncRNA qRT-PCR|Western blotting 2021 Centrifugation|ExoQuick Kit Exosomes 1534 33589572 Homo sapiens Exosomal long non-coding RNA LINC00662 promotes non-small cell lung cancer progression by miR-320d/E2F1 axis Plasma ts Healthy Protein|lncRNA qRT-PCR|Western blotting 2021 Centrifugation|ExoQuick Kit Exosomes 1535 33589572 Homo sapiens Exosomal long non-coding RNA LINC00662 promotes non-small cell lung cancer progression by miR-320d/E2F1 axis Lung cancer cells cl HCC827 Protein Western blotting 2021 Centrifugation|ExoQuick Kit Exosomes 1536 33589572 Homo sapiens Exosomal long non-coding RNA LINC00662 promotes non-small cell lung cancer progression by miR-320d/E2F1 axis Lung cancer cells cl A549 Protein Western blotting 2021 Centrifugation|ExoQuick Kit Exosomes 1537 33523480 Homo sapiens Human fibroblast-derived extracellular vesicles promote hair growth in cultured human hair follicles Fibroblasts cl CCD-1135-SK Protein Western blotting|Flow cytometry 2021 Differential centrifugation|Filtration|Ultracentrifugation|OptiPrep density gradient centrifugation Exosomes 1538 33658392 Homo sapiens Integrative analysis of exosomal microRNA-149-5p in lung adenocarcinoma Lung cancer cells cl A549 Protein|miRNA Western blotting|RT-PCR 2021 Minute High-Efficiency Exosome Precipitation Reagent|Filtration Exosomes 1539 33658392 Homo sapiens Integrative analysis of exosomal microRNA-149-5p in lung adenocarcinoma Lung epithelial cells cl HBE miRNA RT-PCR 2021 Minute High-Efficiency Exosome Precipitation Reagent|Filtration Exosomes 1540 33658392 Homo sapiens Integrative analysis of exosomal microRNA-149-5p in lung adenocarcinoma Lung cancer cells cl A549 Protein|miRNA Western blotting|RT-PCR 2021 Minute High-Efficiency Exosome Precipitation Reagent|Filtration Exosomes 1541 33658392 Homo sapiens Integrative analysis of exosomal microRNA-149-5p in lung adenocarcinoma Lung cancer cells cl A549 Protein|miRNA Western blotting|RT-PCR 2021 Minute High-Efficiency Exosome Precipitation Reagent|Filtration Exosomes 1542 33767144 Homo sapiens Quantitative characterization of extracellular vesicle uptake and content delivery within mammalian cells Cervical cancer cells cl HeLa Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Exosomes 1543 33767144 Homo sapiens Quantitative characterization of extracellular vesicle uptake and content delivery within mammalian cells Cervical cancer cells cl HeLa - top fraction (0%) Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation|Sucrose density gradient centrifugation Exosomes 1544 33767144 Homo sapiens Quantitative characterization of extracellular vesicle uptake and content delivery within mammalian cells Cervical cancer cells cl HeLa - middle fraction (30%) Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation|Sucrose density gradient centrifugation Exosomes 1545 33767144 Homo sapiens Quantitative characterization of extracellular vesicle uptake and content delivery within mammalian cells Cervical cancer cells cl HeLa - bottom fraction (60%) Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation|Sucrose density gradient centrifugation Exosomes 1546 33767144 Homo sapiens Quantitative characterization of extracellular vesicle uptake and content delivery within mammalian cells Cervical cancer cells cl HeLa - middle fraction (30%) Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Exosomes 1547 33638284 Canis lupus familiaris Transglutaminase-2, RNA-binding proteins and mitochondrial proteins selectively traffic to MDCK cell-derived microvesicles following H-Ras-induced epithelial-mesenchymal transition Kidney cells cl MDCK - 10K pellet Protein Western blotting|Mass spectrometry 2021 Differential centrifugation Microvesicles 1548 33638284 Canis lupus familiaris Transglutaminase-2, RNA-binding proteins and mitochondrial proteins selectively traffic to MDCK cell-derived microvesicles following H-Ras-induced epithelial-mesenchymal transition Kidney cells cl MDCK - 100K pellet Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Exosomes 1549 33638284 Canis lupus familiaris Transglutaminase-2, RNA-binding proteins and mitochondrial proteins selectively traffic to MDCK cell-derived microvesicles following H-Ras-induced epithelial-mesenchymal transition Kidney cells cl MDCK (21D1) - 10K pellet Protein Western blotting|Mass spectrometry 2021 Differential centrifugation Microvesicles 1550 33638284 Canis lupus familiaris Transglutaminase-2, RNA-binding proteins and mitochondrial proteins selectively traffic to MDCK cell-derived microvesicles following H-Ras-induced epithelial-mesenchymal transition Kidney cells cl MDCK (21D1) - 100K pellet Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Exosomes 1551 32082513 Homo sapiens Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles Liver cancer cells cl Huh-7 - 10K pellet Protein Western blotting 2020 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1552 32082513 Homo sapiens Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles Liver cancer cells cl Huh-7 - 100K pellet Protein Western blotting 2020 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1553 32082513 Homo sapiens Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles Liver cancer cells cl Huh-7 - 10K pellet Protein Western blotting 2020 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1554 32082513 Homo sapiens Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles Liver cancer cells cl Huh-7 - 100K pellet Protein Western blotting 2020 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1555 32082513 Homo sapiens Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles Liver cancer cells cl Huh-7 - Fraction 6 Protein Western blotting 2020 Centrifugation|Centrifugal ultrafiltration|OptiPrep density gradient centrifugation|Ultracentrifugation Extracellular vesicles 1556 32082513 Homo sapiens Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles Liver cancer cells cl Huh-7 - Fraction 7 Protein Western blotting 2020 Centrifugation|Centrifugal ultrafiltration|OptiPrep density gradient centrifugation|Ultracentrifugation Extracellular vesicles 1557 32082513 Homo sapiens Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles Liver cancer cells cl Huh-7 - Fraction 8 Protein Western blotting 2020 Centrifugation|Centrifugal ultrafiltration|OptiPrep density gradient centrifugation|Ultracentrifugation Extracellular vesicles 1558 32082513 Homo sapiens Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles Liver cancer cells cl Huh-7 - Fraction 9 Protein Western blotting 2020 Centrifugation|Centrifugal ultrafiltration|OptiPrep density gradient centrifugation|Ultracentrifugation Extracellular vesicles 1559 32082513 Homo sapiens Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles Liver cancer cells cl Huh-7 - Fraction 6 Protein Western blotting 2020 Centrifugation|Centrifugal ultrafiltration|OptiPrep density gradient centrifugation|Ultracentrifugation Extracellular vesicles 1560 32082513 Homo sapiens Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles Liver cancer cells cl Huh-7 - Fraction 7 Protein Western blotting 2020 Centrifugation|Centrifugal ultrafiltration|OptiPrep density gradient centrifugation|Ultracentrifugation Extracellular vesicles 1561 32082513 Homo sapiens Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles Liver cancer cells cl Huh-7 - Fraction 8 Protein Western blotting 2020 Centrifugation|Centrifugal ultrafiltration|OptiPrep density gradient centrifugation|Ultracentrifugation Extracellular vesicles 1562 32082513 Homo sapiens Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles Liver cancer cells cl Huh-7 - Fraction 9 Protein Western blotting 2020 Centrifugation|Centrifugal ultrafiltration|OptiPrep density gradient centrifugation|Ultracentrifugation Extracellular vesicles 1563 32082513 Homo sapiens Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles Liver cancer cells cl Huh-7 Protein Western blotting 2020 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1564 32082513 Homo sapiens Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles Liver cancer cells cl Huh-7 Protein Western blotting 2020 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1565 32082513 Homo sapiens Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles Liver cancer cells cl Huh-7 Protein Western blotting 2020 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1566 33523942 Homo sapiens Exosomal delivery of NF-κB inhibitor delays LPS-induced preterm birth and modulates fetal immune cell profile in mouse models Embryonic kidney cells cl HEK293T Protein Western blotting 2021 Centrifugation|Filtration|Size exclusion chromatography Exosomes 1567 33523942 Homo sapiens Exosomal delivery of NF-κB inhibitor delays LPS-induced preterm birth and modulates fetal immune cell profile in mouse models Embryonic kidney cells cl HEK293T Protein Western blotting 2021 Centrifugation|Filtration|Size exclusion chromatography Exosomes 1568 33738083 Homo sapiens Bioorthogonally surface-edited extracellular vesicles based on metabolic glycoengineering for CD44-mediated targeting of inflammatory diseases Breast cancer cells cl MDA‐MB‐231 Protein Western blotting|Immunofluorescence|Flow cytomtery 2021 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1569 33738083 Homo sapiens Bioorthogonally surface-edited extracellular vesicles based on metabolic glycoengineering for CD44-mediated targeting of inflammatory diseases Breast cancer cells cl MDA‐MB‐231 Protein Western blotting|Immunofluorescence|Flow cytomtery 2021 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1570 33738083 Homo sapiens Bioorthogonally surface-edited extracellular vesicles based on metabolic glycoengineering for CD44-mediated targeting of inflammatory diseases Colorectal cancer cells cl HCT116 Protein Immunofluorescence|Flow cytomtery 2021 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1571 33738083 Homo sapiens Bioorthogonally surface-edited extracellular vesicles based on metabolic glycoengineering for CD44-mediated targeting of inflammatory diseases Colorectal cancer cells cl HCT116 Protein Immunofluorescence|Flow cytomtery 2021 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1572 33785738 Mus musculus Selective packaging of mitochondrial proteins into extracellular vesicles prevents the release of mitochondrial DAMPs Fibroblasts cl MEF Protein Western blotting|qPCR 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1573 33785738 Mus musculus Selective packaging of mitochondrial proteins into extracellular vesicles prevents the release of mitochondrial DAMPs Macrophage cl RAW264.7 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1574 33785738 Homo sapiens Selective packaging of mitochondrial proteins into extracellular vesicles prevents the release of mitochondrial DAMPs Osteosarcoma cells cl U2OS Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1575 33785738 Mus musculus Selective packaging of mitochondrial proteins into extracellular vesicles prevents the release of mitochondrial DAMPs Fibroblasts cl MEF-derived EVs treated with Trypsin Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1576 33785738 Mus musculus Selective packaging of mitochondrial proteins into extracellular vesicles prevents the release of mitochondrial DAMPs Fibroblasts cl MEF-derived EVs treated with Trypsin and Triton X-100 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1577 33785738 Mus musculus Selective packaging of mitochondrial proteins into extracellular vesicles prevents the release of mitochondrial DAMPs Fibroblasts cl MEF Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1578 33785738 Mus musculus Selective packaging of mitochondrial proteins into extracellular vesicles prevents the release of mitochondrial DAMPs Fibroblasts cl MEF Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1579 33785738 Mus musculus Selective packaging of mitochondrial proteins into extracellular vesicles prevents the release of mitochondrial DAMPs Fibroblasts cl MEF ProteinmRNA Western blotting|qPCR 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1580 33785738 Mus musculus Selective packaging of mitochondrial proteins into extracellular vesicles prevents the release of mitochondrial DAMPs Fibroblasts cl MEF Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1581 33785738 Homo sapiens Selective packaging of mitochondrial proteins into extracellular vesicles prevents the release of mitochondrial DAMPs Osteosarcoma cells cl U2OS Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1582 33785738 Homo sapiens Selective packaging of mitochondrial proteins into extracellular vesicles prevents the release of mitochondrial DAMPs Osteosarcoma cells cl U2OS Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1583 33686255 Homo sapiens Extracellular vesicle drug occupancy enables real-time monitoring of targeted cancer therapy. Lung cancer cells cl H3255 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1584 33692129 Macaca fascicularis Small extracellular vesicles containing miR-486-5p promote angiogenesis after myocardial infarction in mice and nonhuman primates Mesenchymal stem cells cl MSCs - Fraction 6 Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation|OptiPrep density gradient centrifugation Small extracellular vesicles 1585 33692129 Macaca fascicularis Small extracellular vesicles containing miR-486-5p promote angiogenesis after myocardial infarction in mice and nonhuman primates Mesenchymal stem cells cl MSCs - Fraction 7 Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation|OptiPrep density gradient centrifugation Small extracellular vesicles 1586 33692129 Macaca fascicularis Small extracellular vesicles containing miR-486-5p promote angiogenesis after myocardial infarction in mice and nonhuman primates Mesenchymal stem cells cl MSCs - Fraction 8 Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation|OptiPrep density gradient centrifugation Small extracellular vesicles 1587 33692129 Macaca fascicularis Small extracellular vesicles containing miR-486-5p promote angiogenesis after myocardial infarction in mice and nonhuman primates Mesenchymal stem cells cl MSCs - Fraction 9 Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation|OptiPrep density gradient centrifugation Small extracellular vesicles 1588 33692129 Macaca fascicularis Small extracellular vesicles containing miR-486-5p promote angiogenesis after myocardial infarction in mice and nonhuman primates Mesenchymal stem cells cl MSCs Protein|miRNA Immuno-EM|Western blotting|Microarray 2021 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 1589 33692129 Macaca fascicularis Small extracellular vesicles containing miR-486-5p promote angiogenesis after myocardial infarction in mice and nonhuman primates Mesenchymal stem cells cl MSCs miRNA Microarray 2021 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 1590 34282141 Homo sapiens Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9 Cervical cancer cells cl HeLa - 2K pellet Protein Western blotting 2021 Centrifugation Extracellular vesicles 1591 34282141 Homo sapiens Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9 Cervical cancer cells cl HeLa - 10K pellet Protein Western blotting 2021 Differential centrifugation Extracellular vesicles 1592 34282141 Homo sapiens Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9 Cervical cancer cells cl HeLa - 200K pellet Protein Western blotting|Immuno-EM 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1593 34282141 Homo sapiens Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9 Cervical cancer cells cl HeLa - CD63 pull-down fraction Protein Western blotting 2021 Centrifugal ultrafiltration|Immunoaffinity capture Extracellular vesicles 1594 34282141 Homo sapiens Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9 Cervical cancer cells cl HeLa - CD63 flow-through fraction Protein Western blotting 2021 Centrifugal ultrafiltration|Immunoaffinity capture Extracellular vesicles 1595 34282141 Homo sapiens Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9 Cervical cancer cells cl HeLa - CD9 pull-down fraction Protein Western blotting 2021 Centrifugal ultrafiltration|Immunoaffinity capture Extracellular vesicles 1596 34282141 Homo sapiens Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9 Cervical cancer cells cl HeLa - CD9 flow-through fraction Protein Western blotting 2021 Centrifugal ultrafiltration|Immunoaffinity capture Extracellular vesicles 1597 34282141 Homo sapiens Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9 Cervical cancer cells cl HeLa - IgG control flow-through fraction Protein Western blotting 2021 Centrifugal ultrafiltration|Immunoaffinity capture Extracellular vesicles 1598 34282141 Homo sapiens Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9 Cervical cancer cells cl HeLa - mixed conditioned media - IgG control flow-through fraction Protein Western blotting 2021 Centrifugal ultrafiltration|Immunoaffinity capture Extracellular vesicles 1599 34282141 Homo sapiens Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9 Cervical cancer cells cl HeLa - mixed conditioned media - CD63 pull-down fraction Protein Western blotting 2021 Centrifugal ultrafiltration|Immunoaffinity capture Extracellular vesicles 1600 34282141 Homo sapiens Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9 Cervical cancer cells cl HeLa - mixed conditioned media - CD63 flow-through fraction Protein Western blotting 2021 Centrifugal ultrafiltration|Immunoaffinity capture Extracellular vesicles 1601 34282141 Homo sapiens Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9 Cervical cancer cells cl HeLa - mixed conditioned media - CD9 pull-down fraction Protein Western blotting 2021 Centrifugal ultrafiltration|Immunoaffinity capture Extracellular vesicles 1602 34282141 Homo sapiens Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9 Cervical cancer cells cl HeLa - mixed conditioned media - CD9 flow-through fraction Protein Western blotting 2021 Centrifugal ultrafiltration|Immunoaffinity capture Extracellular vesicles 1603 34282141 Homo sapiens Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9 Cervical cancer cells cl HeLa - 10K pellet Protein Western blotting 2021 Differential centrifugation Extracellular vesicles 1604 34282141 Homo sapiens Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9 Cervical cancer cells cl HeLa - 200K pellet Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1605 34282141 Homo sapiens Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9 Cervical cancer cells cl HeLa - pellet Protein Western blotting 2021 Differential centrifugation Extracellular vesicles 1606 34282141 Homo sapiens Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9 Cervical cancer cells cl HeLa - 200K pellet Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1607 34282141 Homo sapiens Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9 Cervical cancer cells cl HeLa - CD63 pull-down fraction Protein Western blotting|Mass spectrometry 2021 Centrifugal ultrafiltration|Immunoaffinity capture Extracellular vesicles 1608 34282141 Homo sapiens Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9 Cervical cancer cells cl HeLa - CD63 flow-through fraction Protein Western blotting 2021 Centrifugal ultrafiltration|Immunoaffinity capture Extracellular vesicles 1609 34282141 Homo sapiens Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9 Cervical cancer cells cl HeLa - CD63 pull-down fraction Protein Western blotting 2021 Centrifugal ultrafiltration|Immunoaffinity capture Extracellular vesicles 1610 34282141 Homo sapiens Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9 Cervical cancer cells cl HeLa - CD63 flow-through fraction Protein Western blotting 2021 Centrifugal ultrafiltration|Immunoaffinity capture Extracellular vesicles 1611 34282141 Homo sapiens Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9 Cervical cancer cells cl HeLa - CD9 pull-down fraction Protein Western blotting|Mass spectrometry 2021 Centrifugal ultrafiltration|Immunoaffinity capture Extracellular vesicles 1612 34282141 Homo sapiens Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9 Cervical cancer cells cl HeLa - CD9 flow-through fraction Protein Western blotting 2021 Centrifugal ultrafiltration|Immunoaffinity capture Extracellular vesicles 1613 34282141 Homo sapiens Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9 Cervical cancer cells cl HeLa Protein Mass spectrometry 2021 Centrifugal ultrafiltration|Immunoaffinity capture Extracellular vesicles 1614 34282141 Homo sapiens Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9 Cervical cancer cells cl HeLa Protein Mass spectrometry 2021 Centrifugal ultrafiltration|Immunoaffinity capture Extracellular vesicles 1615 34282141 Homo sapiens Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9 Cervical cancer cells cl HeLa Protein Mass spectrometry 2021 Centrifugal ultrafiltration|Immunoaffinity capture Extracellular vesicles 1616 34282141 Homo sapiens Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9 Cervical cancer cells cl HeLa Protein Mass spectrometry 2021 Centrifugal ultrafiltration|Immunoaffinity capture Extracellular vesicles 1617 34282141 Homo sapiens Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9 Cervical cancer cells cl HeLa - 10K pellet Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1618 34282141 Homo sapiens Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9 Cervical cancer cells cl HeLa - 10K pellet Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1619 34282141 Homo sapiens Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9 Cervical cancer cells cl HeLa - 200K pellet Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1620 34282141 Homo sapiens Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9 Cervical cancer cells cl HeLa - 200K pellet Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1621 34282141 Homo sapiens Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9 Cervical cancer cells cl HeLa - 200K pellet Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1622 34796683 Homo sapiens High TSPAN8 expression in epithelial cancer cell-derived small extracellular vesicles promote confined diffusion and pronounced uptake Breast cancer cells cl T-47D Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1623 34796683 Homo sapiens High TSPAN8 expression in epithelial cancer cell-derived small extracellular vesicles promote confined diffusion and pronounced uptake Breast cancer cells cl T-47D Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1624 34012515 Homo sapiens CD9 inhibition reveals a functional connection of extracellular vesicle secretion with mitophagy in melanoma cells Melanoma cells cl SK‐MEL‐147 Protein LC-MS/MS|Western blotting 2021 Differential centrifugation|Centrifugal ultrafiltration|Size exclusion chromatography Extracellular vesicles 1625 34012515 Homo sapiens CD9 inhibition reveals a functional connection of extracellular vesicle secretion with mitophagy in melanoma cells Melanoma cells cl SK‐MEL‐147 Protein LC-MS/MS|Western blotting 2021 Differential centrifugation|Centrifugal ultrafiltration|Size exclusion chromatography Extracellular vesicles 1626 34012515 Homo sapiens CD9 inhibition reveals a functional connection of extracellular vesicle secretion with mitophagy in melanoma cells Melanoma cells cl SK‐MEL‐147 Protein LC-MS/MS|Western blotting 2021 Differential centrifugation|Centrifugal ultrafiltration|Size exclusion chromatography Extracellular vesicles 1627 34012515 Homo sapiens CD9 inhibition reveals a functional connection of extracellular vesicle secretion with mitophagy in melanoma cells Melanoma cells cl SK‐MEL‐147 Protein|Lipid LC-MS/MS|MALDI-MS|Western blotting 2021 Differential centrifugation|Centrifugal ultrafiltration|Size exclusion chromatography Extracellular vesicles 1628 34012515 Homo sapiens CD9 inhibition reveals a functional connection of extracellular vesicle secretion with mitophagy in melanoma cells Melanoma cells cl SK‐MEL‐147 Protein|Lipid LC-MS/MS|MALDI-MS|Western blotting 2021 Differential centrifugation|Centrifugal ultrafiltration|Size exclusion chromatography Extracellular vesicles 1629 29348617 Mus musculus Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures Primary cortical neurons ts C57BL/6 Protein|Lipid Western blotting|LC-MS 2018 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1630 29348617 Mus musculus Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures Primary cortical neurons ts C57BL/6 Protein|Lipid Western blotting|LC-MS 2018 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1631 29348617 Mus musculus Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures Neuroblastoma cells cl N2a Protein|Lipid Western blotting|LC-MS 2018 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1632 29348617 Mus musculus Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures Neuroblastoma cells cl N2a Protein|Lipid Western blotting|LC-MS 2018 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1633 29348617 Mus musculus Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures Neuroblastoma cells cl N2a - 10K pellet Protein Western blotting 2018 Differential centrifugation Extracellular vesicles 1634 29348617 Mus musculus Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures Neuroblastoma cells cl N2a - 100K pellet Protein Western blotting 2018 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1635 29348617 Mus musculus Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures Neuroblastoma cells cl N2a - 10K pellet Protein Western blotting 2018 Differential centrifugation Extracellular vesicles 1636 29348617 Mus musculus Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures Neuroblastoma cells cl N2a - 100K pellet Protein Western blotting 2018 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1637 29348617 Mus musculus Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures Neuroblastoma cells cl N2a Protein|Lipid Western blotting|LC-MS 2018 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1638 29348617 Mus musculus Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures Primary cortical neurons ts C57BL/6 Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1639 29348617 Mus musculus Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures Primary cortical neurons ts C57BL/6 Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1640 29348617 Mus musculus Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures Primary cortical neurons ts C57BL/6 - Fraction 4 Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation|OptiPrep density gradient centrifugation Extracellular vesicles 1641 29348617 Mus musculus Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures Primary cortical neurons ts C57BL/6 - Fraction 5 Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation|OptiPrep density gradient centrifugation Extracellular vesicles 1642 29348617 Mus musculus Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures Primary cortical neurons ts C57BL/6 - Fraction 6 Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation|OptiPrep density gradient centrifugation Extracellular vesicles 1643 29348617 Mus musculus Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures Primary cortical neurons ts C57BL/6 - Fraction 7 Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation|OptiPrep density gradient centrifugation Extracellular vesicles 1644 29348617 Mus musculus Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures Primary cortical neurons ts C57BL/6 - Fraction 8 Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation|OptiPrep density gradient centrifugation Extracellular vesicles 1645 29348617 Mus musculus Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures Forebrain neurons ts C57BL/6 Pik3c3flox/flox Protein|Lipid Western blotting|LC-MS 2018 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1646 29348617 Mus musculus Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures Forebrain neurons ts C57BL/6 Pik3c3flox/flox crossed with transgenic C57BL/6 CaMKIIα-Cre Protein|Lipid Western blotting|LC-MS 2018 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1647 29348617 Mus musculus Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures Neuroblastoma cells cl N2a Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1648 29348617 Mus musculus Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures Neuroblastoma cells cl N2a Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1649 29348617 Mus musculus Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures Neuroblastoma cells cl N2a Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1650 29348617 Mus musculus Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures Neuroblastoma cells cl N2a Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1651 29348617 Mus musculus Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures Neuroblastoma cells cl N2a Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1652 29348617 Mus musculus Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures Neuroblastoma cells cl N2a Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1653 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Glioblastoma cells cl U87 Protein|mRNA RT-qPCR|Flow cytometry 2021 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1654 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Glioblastoma cells cl U87 Protein|mRNA RT-qPCR|Flow cytometry 2021 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1655 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Glioblastoma cells cl U87 Protein|mRNA RT-qPCR|Flow cytometry 2021 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1656 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Glioblastoma cells cl U87 Protein|mRNA RT-qPCR|Flow cytometry 2021 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1657 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Foreskin fibroblasts cl BJ Protein|mRNA RT-qPCR|Western blotting|Mass spectrometry|Flow cytometry 2021 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1658 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Pancreatic cancer cells cl BxPC3 Protein|mRNA RT-qPCR|Western blotting|Mass spectrometry|Flow cytometry 2021 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1659 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Embryonic kidney cells cl HEK293T Protein|mRNA RT-qPCR|Western blotting|Mass spectrometry|Flow cytometry 2021 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1660 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Pancreatic duct epithelial cells cl HPDE Protein|mRNA RT-qPCR|Western blotting|Mass spectrometry|Flow cytometry 2021 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1661 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Pancreatic duct epithelial cells cl HPNE Protein|mRNA RT-qPCR|Western blotting|Mass spectrometry|Flow cytometry 2021 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1662 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker T lymphocytes cl Jurkat Protein|mRNA RT-qPCR|Western blotting|Mass spectrometry|Flow cytometry 2021 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1663 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Mammary cancer-associated fibroblasts cl mCAF Protein|mRNA RT-qPCR|Western blotting|Mass spectrometry|Flow cytometry 2021 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1664 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Breast cancer cells cl MCF7 Protein|mRNA RT-qPCR|Western blotting|Mass spectrometry|Flow cytometry 2021 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1665 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Normal mammary epithelial cells cl MCF10A Protein|mRNA RT-qPCR|Western blotting|Mass spectrometry|Flow cytometry 2021 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1666 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Breast cancer cells cl MDA-MB-231 Protein|mRNA RT-qPCR|Western blotting|Mass spectrometry|Flow cytometry 2021 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1667 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Pancreatic cancer cells cl PANC-1 Protein|mRNA RT-qPCR|Western blotting|Mass spectrometry|Flow cytometry 2021 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1668 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Pluripotent stem cells cl PSC Protein|mRNA RT-qPCR|Western blotting|Mass spectrometry|Flow cytometry 2021 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1669 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Lymphoma cells cl Raji Protein|mRNA RT-qPCR|Western blotting|Mass spectrometry|Flow cytometry 2021 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1670 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Monocytic leukemia cells cl THP-1 Protein|mRNA RT-qPCR|Western blotting|Mass spectrometry|Flow cytometry 2021 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1671 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Embryonic kidney cells cl HEK293T - Exo-rich fractions 7-10 pooled Protein Western blotting|Mass spectrometry 2021 Differential centrifugation|Filtration|Ultracentrifugation|Size exclusion chromatography Exosomes 1672 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Embryonic kidney cells cl HEK293T - Exo-rich fractions 1-6 pooled Protein Mass spectrometry 2021 Differential centrifugation|Filtration|Ultracentrifugation|OptiPrep density gradient centrifugation Exosomes 1673 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Embryonic kidney cells cl HEK293T - Fraction 1 Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation|OptiPrep density gradient centrifugation Exosomes 1674 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Embryonic kidney cells cl HEK293T - Fraction 2 Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation|OptiPrep density gradient centrifugation Exosomes 1675 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Embryonic kidney cells cl HEK293T - Fraction 3 Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation|OptiPrep density gradient centrifugation Exosomes 1676 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Embryonic kidney cells cl HEK293T - Fraction 4 Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation|OptiPrep density gradient centrifugation Exosomes 1677 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Embryonic kidney cells cl HEK293T - Fraction 5 Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation|OptiPrep density gradient centrifugation Exosomes 1678 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Breast cancer cells cl MDA-MB-231 - Exo-rich fractions 7-10 pooled Protein Western blotting|Mass spectrometry 2021 Differential centrifugation|Filtration|Ultracentrifugation|Size exclusion chromatography Exosomes 1679 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Breast cancer cells cl MDA-MB-231 - Exo-rich fractions 1-6 pooled Protein Mass spectrometry 2021 Differential centrifugation|Filtration|Ultracentrifugation|OptiPrep density gradient centrifugation Exosomes 1680 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Breast cancer cells cl MDA-MB-231 - Fraction 1 Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation|OptiPrep density gradient centrifugation Exosomes 1681 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Breast cancer cells cl MDA-MB-231 - Fraction 2 Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation|OptiPrep density gradient centrifugation Exosomes 1682 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Breast cancer cells cl MDA-MB-231 - Fraction 3 Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation|OptiPrep density gradient centrifugation Exosomes 1683 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Breast cancer cells cl MDA-MB-231 - Fraction 4 Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation|OptiPrep density gradient centrifugation Exosomes 1684 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Breast cancer cells cl MDA-MB-231 - Fraction 5 Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation|OptiPrep density gradient centrifugation Exosomes 1685 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Breast cancer cells cl MDA-MB-231 - Fraction 6 Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation|OptiPrep density gradient centrifugation Exosomes 1686 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Pancreatic cancer cells cl PANC-1 - Exo-rich fractions 7-10 pooled Protein Western blotting|Mass spectrometry 2021 Differential centrifugation|Filtration|Ultracentrifugation|Size exclusion chromatography Exosomes 1687 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Pancreatic cancer cells cl PANC-1 - Exo-rich fractions 1-6 pooled Protein Mass spectrometry 2021 Differential centrifugation|Filtration|Ultracentrifugation|OptiPrep density gradient centrifugation Exosomes 1688 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Pancreatic cancer cells cl PANC-1 - Fraction 1 Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation|OptiPrep density gradient centrifugation Exosomes 1689 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Pancreatic cancer cells cl PANC-1 - Fraction 2 Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation|OptiPrep density gradient centrifugation Exosomes 1690 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Pancreatic cancer cells cl PANC-1 - Fraction 3 Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation|OptiPrep density gradient centrifugation Exosomes 1691 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Pancreatic cancer cells cl PANC-1 - Fraction 4 Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation|OptiPrep density gradient centrifugation Exosomes 1692 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Pancreatic cancer cells cl PANC-1 - Fraction 5 Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation|OptiPrep density gradient centrifugation Exosomes 1693 34108659 Mus musculus Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Breast cancer cells cl 4T1 Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1694 34108659 Mus musculus Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Melanoma cells cl B16-F10 Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1695 34108659 Mus musculus Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Colorectal cancer cells cl MC-38 Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1696 34108659 Mus musculus Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Embryonic fibroblasts cl NIH-3T3 Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1697 34108659 Mus musculus Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Monocyte/macrophage-like cells cl RAW 264.7 Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1698 34108659 Mus musculus Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Serum ts C57BL/6J Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1699 34108659 Bos taurus Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Serum ts Fetal bovine Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1700 34108659 Equus caballus Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Serum ts Horse Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1701 34108659 Capra hircus Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Serum ts Goat Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1702 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Urine ts Bladder cancer patients Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1703 34108659 Homo sapiens Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Plasma ts Healthy Protein Western blotting|Flow cytometry 2021 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1704 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Induced pluripotent stem cell-derived neurons cl iNGN - Fraction 8 Protein SIMOA 2021 Differential centrifugation|Ultracentrifugation|Size exclusion chromatography Extracellular vesicles 1705 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Induced pluripotent stem cell-derived neurons cl iNGN - Fraction 9 Protein SIMOA 2021 Differential centrifugation|Ultracentrifugation|Size exclusion chromatography Extracellular vesicles 1706 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Induced pluripotent stem cell-derived neurons cl iNGN - Fraction 10 Protein SIMOA 2021 Differential centrifugation|Ultracentrifugation|Size exclusion chromatography Extracellular vesicles 1707 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Induced pluripotent stem cell-derived neurons cl iNGN - Fraction 11 Protein SIMOA 2021 Differential centrifugation|Ultracentrifugation|Size exclusion chromatography Extracellular vesicles 1708 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Induced pluripotent stem cell-derived neurons cl iNGN - Fraction 12 Protein SIMOA 2021 Differential centrifugation|Ultracentrifugation|Size exclusion chromatography Extracellular vesicles 1709 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Induced pluripotent stem cell-derived neurons cl iNGN - Fraction 13 Protein SIMOA 2021 Differential centrifugation|Ultracentrifugation|Size exclusion chromatography Extracellular vesicles 1710 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Induced pluripotent stem cell-derived neurons cl iNGN - Fraction 14 Protein SIMOA 2021 Differential centrifugation|Ultracentrifugation|Size exclusion chromatography Extracellular vesicles 1711 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Induced pluripotent stem cell-derived neurons cl iNGN - Fraction 15 Protein SIMOA 2021 Differential centrifugation|Ultracentrifugation|Size exclusion chromatography Extracellular vesicles 1712 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Cerebrospinal fluid ts Fraction 6 Protein SIMOA 2021 Centrifugal filtration|Size exclusion chromatography Extracellular vesicles 1713 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Cerebrospinal fluid ts Fraction 7 Protein SIMOA 2021 Centrifugal filtration|Size exclusion chromatography Extracellular vesicles 1714 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Cerebrospinal fluid ts Fraction 8 Protein SIMOA 2021 Centrifugal filtration|Size exclusion chromatography Extracellular vesicles 1715 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Cerebrospinal fluid ts Fraction 9 Protein SIMOA 2021 Centrifugal filtration|Size exclusion chromatography Extracellular vesicles 1716 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Cerebrospinal fluid ts Fraction 10 Protein SIMOA 2021 Centrifugal filtration|Size exclusion chromatography Extracellular vesicles 1717 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Cerebrospinal fluid ts Fraction 11 Protein SIMOA 2021 Centrifugal filtration|Size exclusion chromatography Extracellular vesicles 1718 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Cerebrospinal fluid ts Fraction 12 Protein SIMOA 2021 Centrifugal filtration|Size exclusion chromatography Extracellular vesicles 1719 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Cerebrospinal fluid ts Fraction 13 Protein SIMOA 2021 Centrifugal filtration|Size exclusion chromatography Extracellular vesicles 1720 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Cerebrospinal fluid ts Fraction 14 Protein SIMOA 2021 Centrifugal filtration|Size exclusion chromatography Extracellular vesicles 1721 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Cerebrospinal fluid ts Fraction 15 Protein SIMOA 2021 Centrifugal filtration|Size exclusion chromatography Extracellular vesicles 1722 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Cerebrospinal fluid ts Fraction 16 Protein SIMOA 2021 Centrifugal filtration|Size exclusion chromatography Extracellular vesicles 1723 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Cerebrospinal fluid ts Fraction 17 Protein SIMOA 2021 Centrifugal filtration|Size exclusion chromatography Extracellular vesicles 1724 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Plasma ts Fraction 6 Protein SIMOA 2021 Centrifugal filtration|Size exclusion chromatography Extracellular vesicles 1725 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Plasma ts Fraction 7 Protein SIMOA|ELISA 2021 Centrifugal filtration|Size exclusion chromatography Extracellular vesicles 1726 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Plasma ts Fraction 8 Protein SIMOA|ELISA 2021 Centrifugal filtration|Size exclusion chromatography Extracellular vesicles 1727 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Plasma ts Fraction 9 Protein SIMOA|ELISA 2021 Centrifugal filtration|Size exclusion chromatography Extracellular vesicles 1728 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Plasma ts Fraction 10 Protein SIMOA 2021 Centrifugal filtration|Size exclusion chromatography Extracellular vesicles 1729 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Plasma ts Fraction 11 Protein SIMOA 2021 Centrifugal filtration|Size exclusion chromatography Extracellular vesicles 1730 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Plasma ts Fraction 12 Protein SIMOA 2021 Centrifugal filtration|Size exclusion chromatography Extracellular vesicles 1731 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Plasma ts Fraction 13 Protein SIMOA 2021 Centrifugal filtration|Size exclusion chromatography Extracellular vesicles 1732 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Plasma ts Fraction 14 Protein SIMOA 2021 Centrifugal filtration|Size exclusion chromatography Extracellular vesicles 1733 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Plasma ts Fraction 15 Protein SIMOA 2021 Centrifugal filtration|Size exclusion chromatography Extracellular vesicles 1734 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Plasma ts Fraction 16 Protein SIMOA 2021 Centrifugal filtration|Size exclusion chromatography Extracellular vesicles 1735 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Plasma ts Fraction 17 Protein SIMOA 2021 Centrifugal filtration|Size exclusion chromatography Extracellular vesicles 1736 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Cerebrospinal fluid ts Fraction 1 Protein SIMOA 2021 Centrifugal filtration|OptiPrep density gradient centrifugation Extracellular vesicles 1737 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Cerebrospinal fluid ts Fraction 2 Protein SIMOA 2021 Centrifugal filtration|OptiPrep density gradient centrifugation Extracellular vesicles 1738 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Cerebrospinal fluid ts Fraction 3 Protein SIMOA 2021 Centrifugal filtration|OptiPrep density gradient centrifugation Extracellular vesicles 1739 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Cerebrospinal fluid ts Fraction 4 Protein SIMOA 2021 Centrifugal filtration|OptiPrep density gradient centrifugation Extracellular vesicles 1740 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Cerebrospinal fluid ts Fraction 5 Protein SIMOA 2021 Centrifugal filtration|OptiPrep density gradient centrifugation Extracellular vesicles 1741 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Cerebrospinal fluid ts Fraction 6 Protein SIMOA 2021 Centrifugal filtration|OptiPrep density gradient centrifugation Extracellular vesicles 1742 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Cerebrospinal fluid ts Fraction 7 Protein SIMOA 2021 Centrifugal filtration|OptiPrep density gradient centrifugation Extracellular vesicles 1743 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Cerebrospinal fluid ts Fraction 8 Protein SIMOA 2021 Centrifugal filtration|OptiPrep density gradient centrifugation Extracellular vesicles 1744 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Cerebrospinal fluid ts Fraction 9 Protein SIMOA 2021 Centrifugal filtration|OptiPrep density gradient centrifugation Extracellular vesicles 1745 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Cerebrospinal fluid ts Fraction 10 Protein SIMOA 2021 Centrifugal filtration|OptiPrep density gradient centrifugation Extracellular vesicles 1746 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Cerebrospinal fluid ts Fraction 11 Protein SIMOA 2021 Centrifugal filtration|OptiPrep density gradient centrifugation Extracellular vesicles 1747 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Plasma ts Fraction 1 Protein SIMOA 2021 Centrifugal filtration|OptiPrep density gradient centrifugation Extracellular vesicles 1748 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Plasma ts Fraction 2 Protein SIMOA 2021 Centrifugal filtration|OptiPrep density gradient centrifugation Extracellular vesicles 1749 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Plasma ts Fraction 3 Protein SIMOA 2021 Centrifugal filtration|OptiPrep density gradient centrifugation Extracellular vesicles 1750 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Plasma ts Fraction 4 Protein SIMOA 2021 Centrifugal filtration|OptiPrep density gradient centrifugation Extracellular vesicles 1751 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Plasma ts Fraction 5 Protein SIMOA 2021 Centrifugal filtration|OptiPrep density gradient centrifugation Extracellular vesicles 1752 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Plasma ts Fraction 6 Protein SIMOA 2021 Centrifugal filtration|OptiPrep density gradient centrifugation Extracellular vesicles 1753 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Plasma ts Fraction 7 Protein SIMOA 2021 Centrifugal filtration|OptiPrep density gradient centrifugation Extracellular vesicles 1754 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Plasma ts Fraction 8 Protein SIMOA 2021 Centrifugal filtration|OptiPrep density gradient centrifugation Extracellular vesicles 1755 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Plasma ts Fraction 9 Protein SIMOA 2021 Centrifugal filtration|OptiPrep density gradient centrifugation Extracellular vesicles 1756 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Plasma ts Fraction 10 Protein SIMOA 2021 Centrifugal filtration|OptiPrep density gradient centrifugation Extracellular vesicles 1757 34092791 Homo sapiens L1CAM is not associated with extracellular vesicles in human cerebrospinal fluid or plasma Plasma ts Fraction 11 Protein SIMOA 2021 Centrifugal filtration|OptiPrep density gradient centrifugation Extracellular vesicles 1758 35918900 Homo sapiens Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL) Breast cancer cells cl MDA-MB-231 Protein Mass spectometry|Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1759 35918900 Homo sapiens Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL) Breast cancer cells cl LM2 Protein Mass spectometry 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1760 35918900 Homo sapiens Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL) Breast cancer cells cl MDA-MB-231 Protein Mass spectometry 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1761 35918900 Homo sapiens Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL) Breast cancer cells cl LM2 Protein Mass spectometry 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1762 35933512 Mus musculus Neutrophils restrain sepsis associated coagulopathy via extracellular vesicles carrying superoxide dismutase 2 in a murine model of lipopolysaccharide induced sepsis Vasculature lavage fluid ts Circulating neutrophils from PhAMfloxed × Mrp8-Cre mice - Pellet 1 Protein Western blotting 2022 Differential centrifugation Extracellular vesicles 1763 35933512 Mus musculus Neutrophils restrain sepsis associated coagulopathy via extracellular vesicles carrying superoxide dismutase 2 in a murine model of lipopolysaccharide induced sepsis Vasculature lavage fluid ts Circulating neutrophils from PhAMfloxed × Mrp8-Cre mice - Pellet 2 Protein Western blotting 2022 Differential centrifugation Extracellular vesicles 1764 35933512 Mus musculus Neutrophils restrain sepsis associated coagulopathy via extracellular vesicles carrying superoxide dismutase 2 in a murine model of lipopolysaccharide induced sepsis Vasculature lavage fluid ts Circulating neutrophils from PhAMfloxed × Mrp8-Cre mice - Pellet 3 Protein Western blotting 2022 Differential centrifugation Extracellular vesicles 1765 35933512 Mus musculus Neutrophils restrain sepsis associated coagulopathy via extracellular vesicles carrying superoxide dismutase 2 in a murine model of lipopolysaccharide induced sepsis Vasculature lavage fluid ts Circulating neutrophils from PhAMfloxed × Mrp8-Cre mice - Pellet 4 Protein Western blotting 2022 Differential centrifugation Extracellular vesicles 1766 35933512 Mus musculus Neutrophils restrain sepsis associated coagulopathy via extracellular vesicles carrying superoxide dismutase 2 in a murine model of lipopolysaccharide induced sepsis Vasculature lavage fluid ts Circulating neutrophils from PhAMfloxed × Mrp8-Cre mice - Pellet 5 Protein Western blotting 2022 Differential centrifugation Extracellular vesicles 1767 35933512 Mus musculus Neutrophils restrain sepsis associated coagulopathy via extracellular vesicles carrying superoxide dismutase 2 in a murine model of lipopolysaccharide induced sepsis Vasculature lavage fluid ts Circulating neutrophils from PhAMfloxed × Mrp8-Cre mice - Pellet 1 Protein Western blotting 2022 Differential centrifugation Extracellular vesicles 1768 35933512 Mus musculus Neutrophils restrain sepsis associated coagulopathy via extracellular vesicles carrying superoxide dismutase 2 in a murine model of lipopolysaccharide induced sepsis Vasculature lavage fluid ts Circulating neutrophils from PhAMfloxed × Mrp8-Cre mice - Pellet 2 Protein Western blotting 2022 Differential centrifugation Extracellular vesicles 1769 35933512 Mus musculus Neutrophils restrain sepsis associated coagulopathy via extracellular vesicles carrying superoxide dismutase 2 in a murine model of lipopolysaccharide induced sepsis Vasculature lavage fluid ts Circulating neutrophils from PhAMfloxed × Mrp8-Cre mice - Pellet 3 Protein Western blotting 2022 Differential centrifugation Extracellular vesicles 1770 35933512 Mus musculus Neutrophils restrain sepsis associated coagulopathy via extracellular vesicles carrying superoxide dismutase 2 in a murine model of lipopolysaccharide induced sepsis Vasculature lavage fluid ts Circulating neutrophils from PhAMfloxed × Mrp8-Cre mice - Pellet 4 Protein Western blotting 2022 Differential centrifugation Extracellular vesicles 1771 35933512 Mus musculus Neutrophils restrain sepsis associated coagulopathy via extracellular vesicles carrying superoxide dismutase 2 in a murine model of lipopolysaccharide induced sepsis Vasculature lavage fluid ts Circulating neutrophils from PhAMfloxed × Mrp8-Cre mice - Pellet 5 Protein Western blotting 2022 Differential centrifugation Extracellular vesicles 1772 35933512 Mus musculus Neutrophils restrain sepsis associated coagulopathy via extracellular vesicles carrying superoxide dismutase 2 in a murine model of lipopolysaccharide induced sepsis Vasculature lavage fluid ts Circulating neutrophils from C57BL/6J mice - Pellet 1 Protein Western blotting 2022 Differential centrifugation Extracellular vesicles 1773 35933512 Mus musculus Neutrophils restrain sepsis associated coagulopathy via extracellular vesicles carrying superoxide dismutase 2 in a murine model of lipopolysaccharide induced sepsis Vasculature lavage fluid ts Circulating neutrophils from C57BL/6J mice - Pellet 2 Protein Western blotting 2022 Differential centrifugation Extracellular vesicles 1774 35933512 Mus musculus Neutrophils restrain sepsis associated coagulopathy via extracellular vesicles carrying superoxide dismutase 2 in a murine model of lipopolysaccharide induced sepsis Vasculature lavage fluid ts Circulating neutrophils from C57BL/6J mice - Pellet 3 Protein Western blotting 2022 Differential centrifugation Extracellular vesicles 1775 35933512 Mus musculus Neutrophils restrain sepsis associated coagulopathy via extracellular vesicles carrying superoxide dismutase 2 in a murine model of lipopolysaccharide induced sepsis Vasculature lavage fluid ts Circulating neutrophils from C57BL/6J mice - Pellet 4 Protein Western blotting 2022 Differential centrifugation Extracellular vesicles 1776 35933512 Mus musculus Neutrophils restrain sepsis associated coagulopathy via extracellular vesicles carrying superoxide dismutase 2 in a murine model of lipopolysaccharide induced sepsis Vasculature lavage fluid ts Circulating neutrophils from C57BL/6J mice - Pellet 5 Protein Western blotting 2022 Differential centrifugation Extracellular vesicles 1777 35933512 Mus musculus Neutrophils restrain sepsis associated coagulopathy via extracellular vesicles carrying superoxide dismutase 2 in a murine model of lipopolysaccharide induced sepsis Vasculature lavage fluid ts Circulating neutrophils from C57BL/6J mice - Pellet 1 Protein Western blotting 2022 Differential centrifugation Extracellular vesicles 1778 35933512 Mus musculus Neutrophils restrain sepsis associated coagulopathy via extracellular vesicles carrying superoxide dismutase 2 in a murine model of lipopolysaccharide induced sepsis Vasculature lavage fluid ts Circulating neutrophils from C57BL/6J mice - Pellet 2 Protein Western blotting 2022 Differential centrifugation Extracellular vesicles 1779 35933512 Mus musculus Neutrophils restrain sepsis associated coagulopathy via extracellular vesicles carrying superoxide dismutase 2 in a murine model of lipopolysaccharide induced sepsis Vasculature lavage fluid ts Circulating neutrophils from C57BL/6J mice - Pellet 3 Protein Western blotting 2022 Differential centrifugation Extracellular vesicles 1780 35932288 Homo sapiens Specific anti-glioma targeted-delivery strategy of engineered small extracellular vesicles dual-functionalised by Angiopep-2 and TAT peptides Embryonic kidney cells cl HEK293T Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 1781 35932288 Homo sapiens Specific anti-glioma targeted-delivery strategy of engineered small extracellular vesicles dual-functionalised by Angiopep-2 and TAT peptides Embryonic kidney cells cl HEK293T Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 1782 35932288 Homo sapiens Specific anti-glioma targeted-delivery strategy of engineered small extracellular vesicles dual-functionalised by Angiopep-2 and TAT peptides Embryonic kidney cells cl HEK293T Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 1783 35932288 Homo sapiens Specific anti-glioma targeted-delivery strategy of engineered small extracellular vesicles dual-functionalised by Angiopep-2 and TAT peptides Embryonic kidney cells cl HEK293T Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 1784 35927827 Mus musculus Neoantigen-based cancer vaccination using chimeric RNA-loaded dendritic cell-derived extracellular vesicles Dendritic cells cl DC2.4 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1785 35927827 Mus musculus Neoantigen-based cancer vaccination using chimeric RNA-loaded dendritic cell-derived extracellular vesicles Dendritic cells cl DC2.4 Protein Western blotting|Flow cytometry 2022 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1786 35927827 Mus musculus Neoantigen-based cancer vaccination using chimeric RNA-loaded dendritic cell-derived extracellular vesicles Dendritic cells cl DC2.4 Protein Western blotting|Flow cytometry 2022 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1787 36594832 Mus musculus Dynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia Primary cortical neurons ts CXN - C57Bl/6J mice embryos Protein|miRNA Western blotting|qPCR 2023 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1788 36594832 Mus musculus Dynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia Primary cortical neurons ts CXN - C57Bl/6J mice embryos miRNA qPCR 2023 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1789 36594832 Mus musculus Dynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia Neuroblastoma cells cl N2A miRNA qPCR 2023 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1790 36594832 Mus musculus Dynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia Neuroblastoma cells cl N2A miRNA qPCR 2023 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1791 36594832 Mus musculus Dynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia Neuroblastoma cells cl N2A miRNA qPCR 2023 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1792 36594832 Mus musculus Dynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia Neuroblastoma cells cl N2A Protein|miRNA Western blotting|qPCR 2023 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1793 36594832 Mus musculus Dynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia Neuroblastoma cells cl N2A miRNA qPCR 2023 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1794 36594832 Mus musculus Dynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia Neuroblastoma cells cl N2A Protein|miRNA Western blotting|qPCR 2023 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1795 36594832 Mus musculus Dynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia Neuroblastoma cells cl N2A miRNA qPCR 2023 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1796 36594832 Mus musculus Dynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia Neuroblastoma cells cl N2A Protein|miRNA Western blotting|qPCR 2023 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1797 36594832 Mus musculus Dynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia Neuroblastoma cells cl N2A miRNA qPCR 2023 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1798 36594832 Mus musculus Dynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia Neuroblastoma cells cl N2A Protein|miRNA Western blotting|qPCR 2023 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1799 36594832 Mus musculus Dynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia Neuroblastoma cells cl N2A - Fractions 1-4 miRNA qPCR 2023 Size exclusion chromatography Extracellular vesicles 1800 36594832 Mus musculus Dynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia Neuroblastoma cells cl N2A - Fractions 1-4 miRNA qPCR 2023 Size exclusion chromatography Extracellular vesicles 1801 36594832 Mus musculus Dynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia Neuroblastoma cells cl N2A - Fractions 1-4 miRNA qPCR 2023 Size exclusion chromatography Extracellular vesicles 1802 36594832 Mus musculus Dynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia Neuroblastoma cells cl N2A - Fractions 1-4 miRNA qPCR 2023 Size exclusion chromatography Extracellular vesicles 1803 35917363 Homo sapiens CD9 mediates the uptake of extracellular vesicles from cancer-associated fibroblasts that promote pancreatic cancer cell aggressiveness Fibroblasts ts CAF - Pancreatic ductal adenocarcinoma Protein Western blotting|Mass spectometry 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1804 35917363 Homo sapiens CD9 mediates the uptake of extracellular vesicles from cancer-associated fibroblasts that promote pancreatic cancer cell aggressiveness Fibroblasts ts CAF - Pancreatic ductal adenocarcinoma Protein Western blotting|Mass spectometry 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1805 36517516 Homo sapiens Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes Serum ts Breast cancer patients - African American Protein|miRNA Western blotting|qPCR|Small RNA sequencing 2022 ExoQuick Kit Exosomes 1806 36517516 Homo sapiens Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes Serum ts Breast cancer patients - African American Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Exosomes 1807 36517516 Homo sapiens Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes Breast cancer cells cl HCC1806 Protein|miRNA Western blotting|qPCR 2022 Differential centrifugation|Ultracentrifugation Exosomes 1808 36517516 Homo sapiens Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes Breast cancer cells cl MDA-MB-231 miRNA qPCR 2022 ExoQuick Kit Exosomes 1809 36517516 Homo sapiens Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes Breast cancer cells cl MDA-MB-231 miRNA qPCR 2022 Differential centrifugation|Ultracentrifugation Exosomes 1810 36517516 Homo sapiens Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes Breast cancer cells cl MDA-MB-231 miRNA qPCR 2022 ExoQuick Kit Exosomes 1811 36517516 Homo sapiens Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes Breast cancer cells cl MDA-MB-231 miRNA qPCR 2022 Differential centrifugation|Ultracentrifugation Exosomes 1812 36517516 Homo sapiens Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes Serum ts Breast cancer patients - Caucasian American miRNA qPCR|Small RNA sequencing 2022 ExoQuick Kit Exosomes 1813 36517516 Homo sapiens Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes Serum ts Breast cancer patients (ER-) - African American miRNA qPCR 2022 ExoQuick Kit Exosomes 1814 36517516 Homo sapiens Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes Serum ts Breast cancer patients (ER+) - African American miRNA qPCR 2022 ExoQuick Kit Exosomes 1815 36517516 Homo sapiens Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes Serum ts Healthy - African American miRNA qPCR 2022 ExoQuick Kit Exosomes 1816 36517516 Homo sapiens Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes Serum ts Healthy - Caucasian American miRNA qPCR 2022 ExoQuick Kit Exosomes 1817 36517516 Homo sapiens Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes Breast cancer cells cl SKBr3 miRNA qPCR 2022 Differential centrifugation|Ultracentrifugation Exosomes 1818 36517516 Homo sapiens Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes Breast cancer cells cl MDA-MB-468 miRNA qPCR 2022 Differential centrifugation|Ultracentrifugation Exosomes 1819 36517516 Homo sapiens Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes Breast cancer cells cl HCC1500 miRNA qPCR 2022 Differential centrifugation|Ultracentrifugation Exosomes 1820 36517516 Homo sapiens Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes Breast cancer cells cl HCC1569 miRNA qPCR 2022 Differential centrifugation|Ultracentrifugation Exosomes 1821 36517516 Homo sapiens Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes Breast cancer cells cl HCC70 miRNA qPCR 2022 Differential centrifugation|Ultracentrifugation Exosomes 1822 36517516 Homo sapiens Exosomal miR-1304-3p promotes breast cancer progression in African Americans by activating cancer-associated adipocytes Breast cancer cells cl MDAMB175 miRNA qPCR 2022 Differential centrifugation|Ultracentrifugation Exosomes 1823 36494333 Homo sapiens Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis Serum ts Lung adenocarcinoma pateints miRNA qRT-PCR 2022 Total Exosome Isolation Kit Exosomes 1824 36494333 Homo sapiens Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis Serum ts Healthy miRNA qRT-PCR 2022 Total Exosome Isolation Kit Exosomes 1825 36494333 Homo sapiens Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis Serum ts Primary lung adenocarcinoma pateints miRNA qRT-PCR 2022 Total Exosome Isolation Kit Exosomes 1826 36494333 Homo sapiens Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis Serum ts Metastatic lung adenocarcinoma pateints miRNA qRT-PCR 2022 Total Exosome Isolation Kit Exosomes 1827 36494333 Homo sapiens Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis Lung cancer cells cl A549 Protein|miRNA Western blotting|qRT-PCR 2022 Centrifugation|Filtration|ExoQuick Kit Exosomes 1828 36494333 Homo sapiens Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis Lung cancer cells cl H1299 Protein|miRNA Western blotting|qRT-PCR 2022 Centrifugation|Filtration|ExoQuick Kit Exosomes 1829 36494333 Homo sapiens Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis Lung cancer cells cl A549 miRNA qRT-PCR 2022 Centrifugation|Filtration|ExoQuick Kit Exosomes 1830 36494333 Homo sapiens Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis Lung cancer cells cl A549 miRNA qRT-PCR 2022 Centrifugation|Filtration|ExoQuick Kit Exosomes 1831 36494333 Homo sapiens Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis Lung cancer cells cl A549 miRNA qRT-PCR 2022 Centrifugation|Filtration|ExoQuick Kit Exosomes 1832 36494333 Homo sapiens Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis Lung cancer cells cl A549 miRNA qRT-PCR 2022 Centrifugation|Filtration|ExoQuick Kit Exosomes 1833 36494333 Homo sapiens Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis Lung cancer cells cl H1299 miRNA qRT-PCR 2022 Centrifugation|Filtration|ExoQuick Kit Exosomes 1834 36494333 Homo sapiens Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis Lung cancer cells cl H1299 miRNA qRT-PCR 2022 Centrifugation|Filtration|ExoQuick Kit Exosomes 1835 36494333 Homo sapiens Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis Lung cancer cells cl H1299 miRNA qRT-PCR 2022 Centrifugation|Filtration|ExoQuick Kit Exosomes 1836 36494333 Homo sapiens Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis Lung cancer cells cl H1299 miRNA qRT-PCR 2022 Centrifugation|Filtration|ExoQuick Kit Exosomes 1837 36408942 Homo sapiens Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells Mesenchymal stem cells cl UCMSC Protein Western blotting|Mass spectometry 2023 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1838 36408942 Rattus norvegicus Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells Bone marrow mesenchymal stem cells cl BMSC - Passage 6 Protein Western blotting|Mass spectometry 2023 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1839 36408942 Rattus norvegicus Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells Bone marrow mesenchymal stem cells cl BMSC - Passage 7 Protein Western blotting|Mass spectometry 2023 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1840 36408942 Rattus norvegicus Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells Bone marrow mesenchymal stem cells cl BMSC - Passage 8 Protein Western blotting|Mass spectometry 2023 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1841 36408942 Rattus norvegicus Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells Bone marrow mesenchymal stem cells cl BMSC - Passage 9 Protein Western blotting|Mass spectometry 2023 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1842 36408942 Homo sapiens Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells Mesenchymal stem cells cl UCMSC Protein Western blotting 2023 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 1843 36068649 Homo sapiens Extracellular vesicles from colorectal cancer cells promote metastasis via the NOD1 signalling pathway Normal colon fibroblasts cl CCD18Co Protein Western blotting|Mass spectometry 2022 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1844 36068649 Homo sapiens Extracellular vesicles from colorectal cancer cells promote metastasis via the NOD1 signalling pathway Colorectal cancer cells cl HT29 Protein Western blotting|Mass spectometry 2022 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1845 36068649 Homo sapiens Extracellular vesicles from colorectal cancer cells promote metastasis via the NOD1 signalling pathway Colorectal cancer cells cl HCT116 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1846 36068649 Mus musculus Extracellular vesicles from colorectal cancer cells promote metastasis via the NOD1 signalling pathway Colorectal cancer cells cl MC38 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1847 36068649 Homo sapiens Extracellular vesicles from colorectal cancer cells promote metastasis via the NOD1 signalling pathway Plasma ts CRC with liver metastasis - Pateint 1 Protein Western blotting 2022 Centrifugation|Filtration|Exo-spin midi|Centrifugal ultrafiltration Extracellular vesicles 1848 36068649 Homo sapiens Extracellular vesicles from colorectal cancer cells promote metastasis via the NOD1 signalling pathway Plasma ts CRC with liver metastasis - Pateint 2 Protein Western blotting 2022 Centrifugation|Filtration|Exo-spin midi|Centrifugal ultrafiltration Extracellular vesicles 1849 36068649 Homo sapiens Extracellular vesicles from colorectal cancer cells promote metastasis via the NOD1 signalling pathway Plasma ts CRC with liver metastasis - Pateint 3 Protein Western blotting 2022 Centrifugation|Filtration|Exo-spin midi|Centrifugal ultrafiltration Extracellular vesicles 1850 36068649 Homo sapiens Extracellular vesicles from colorectal cancer cells promote metastasis via the NOD1 signalling pathway Plasma ts CRC with liver metastasis - Pateint 4 Protein Western blotting 2022 Centrifugation|Filtration|Exo-spin midi|Centrifugal ultrafiltration Extracellular vesicles 1851 36068649 Homo sapiens Extracellular vesicles from colorectal cancer cells promote metastasis via the NOD1 signalling pathway Plasma ts CRC with liver metastasis - Pateint 5 Protein Western blotting 2022 Centrifugation|Filtration|Exo-spin midi|Centrifugal ultrafiltration Extracellular vesicles 1852 36068649 Homo sapiens Extracellular vesicles from colorectal cancer cells promote metastasis via the NOD1 signalling pathway Plasma ts CRC with liver metastasis - Pateint 6 Protein Western blotting 2022 Centrifugation|Filtration|Exo-spin midi|Centrifugal ultrafiltration Extracellular vesicles 1853 36068649 Homo sapiens Extracellular vesicles from colorectal cancer cells promote metastasis via the NOD1 signalling pathway Plasma ts CRC with liver metastasis - Pateint 7 Protein Western blotting 2022 Centrifugation|Filtration|Exo-spin midi|Centrifugal ultrafiltration Extracellular vesicles 1854 36068649 Homo sapiens Extracellular vesicles from colorectal cancer cells promote metastasis via the NOD1 signalling pathway Plasma ts Healthy - Donor 1 Protein Western blotting 2022 Centrifugation|Filtration|Exo-spin midi|Centrifugal ultrafiltration Extracellular vesicles 1855 36068649 Homo sapiens Extracellular vesicles from colorectal cancer cells promote metastasis via the NOD1 signalling pathway Plasma ts Healthy - Donor 2 Protein Western blotting 2022 Centrifugation|Filtration|Exo-spin midi|Centrifugal ultrafiltration Extracellular vesicles 1856 36068649 Homo sapiens Extracellular vesicles from colorectal cancer cells promote metastasis via the NOD1 signalling pathway Plasma ts Healthy - Donor 3 Protein Western blotting 2022 Centrifugation|Filtration|Exo-spin midi|Centrifugal ultrafiltration Extracellular vesicles 1857 36068649 Homo sapiens Extracellular vesicles from colorectal cancer cells promote metastasis via the NOD1 signalling pathway Plasma ts Healthy - Donor 4 Protein Western blotting 2022 Centrifugation|Filtration|Exo-spin midi|Centrifugal ultrafiltration Extracellular vesicles 1858 36068649 Homo sapiens Extracellular vesicles from colorectal cancer cells promote metastasis via the NOD1 signalling pathway Plasma ts Healthy - Donor 5 Protein Western blotting 2022 Centrifugation|Filtration|Exo-spin midi|Centrifugal ultrafiltration Extracellular vesicles 1859 36068649 Homo sapiens Extracellular vesicles from colorectal cancer cells promote metastasis via the NOD1 signalling pathway Plasma ts Healthy - Donor 6 Protein Western blotting 2022 Centrifugation|Filtration|Exo-spin midi|Centrifugal ultrafiltration Extracellular vesicles 1860 36068649 Homo sapiens Extracellular vesicles from colorectal cancer cells promote metastasis via the NOD1 signalling pathway Plasma ts Healthy - Donor 7 Protein Western blotting 2022 Centrifugation|Filtration|Exo-spin midi|Centrifugal ultrafiltration Extracellular vesicles 1861 35931686 Homo sapiens Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression Chondrocytes ts Osteoarthritic cartilage Protein Western blotting|Mass spectometry 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 1862 35931686 Homo sapiens Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression Chondrocytes ts Healthy cartilage Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 1863 35931686 Homo sapiens Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression Chondrocytes ts Healthy cartilage Protein Western blotting|Mass spectometry 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 1864 35931686 Homo sapiens Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression Chondrocytes cl T/C-28a2 Protein Western blotting|Mass spectometry 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 1865 35931686 Homo sapiens Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression Chondrocytes cl T/C-28a2 Protein Western blotting|Mass spectometry 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 1866 36063142 Mus musculus Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL Embryonic fibroblasts ts E12.5 from Ripk3+/+ mice Protein Western blotting|Mass spectometry 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1867 36063142 Mus musculus Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL Embryonic fibroblasts ts E12.5 from Ripk3+/+ mice Protein Western blotting|Mass spectometry 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1868 36063142 Mus musculus Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL Embryonic fibroblasts ts E12.5 from Ripk3-/- mice Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1869 36063142 Mus musculus Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL Embryonic fibroblasts ts E12.5 from Ripk3-/- mice Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1870 36063142 Mus musculus Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL Embryonic fibroblasts ts E12.5 from Ripk3+/+ mice Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation|Size exclusion chromatography Extracellular vesicles 1871 36063142 Mus musculus Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL Plasma ts Plasma from Ripk3-/- mice Protein Western blotting 2022 Differential centrifugation|ExoQuick Kit Extracellular vesicles 1872 36063142 Mus musculus Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL Plasma ts Plasma from Ripk3+/+ mice Protein Western blotting 2022 Differential centrifugation|ExoQuick Kit Extracellular vesicles 1873 36063142 Homo sapiens Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL Colorectal cancer cells cl HT-29 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1874 36063142 Homo sapiens Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL Colorectal cancer cells cl HT-29 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1875 36063142 Homo sapiens Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL Colorectal cancer cells cl HT-29 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1876 36063142 Homo sapiens Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL Colorectal cancer cells cl HT-29 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1877 36063142 Homo sapiens Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL Colorectal cancer cells cl HT-29 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1878 36063142 Homo sapiens Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL Embryonic kidney cells cl HEK293T Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1879 36063142 Homo sapiens Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL Plasma ts Plasma Protein Western blotting 2022 Differential centrifugation|ExoQuick Kit Extracellular vesicles 1880 36063142 Mus musculus Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL Embryonic fibroblasts ts E12.5 from Ripk3+/+ mice Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1881 36063142 Mus musculus Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL Embryonic fibroblasts ts E12.5 from Ripk3+/+ mice Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1882 36063142 Mus musculus Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL Embryonic fibroblasts ts E12.5 from Ripk3+/+ mice Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1883 36063142 Mus musculus Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL Embryonic fibroblasts ts E12.5 from Ripk3+/+ mice Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1884 36063142 Mus musculus Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL Embryonic fibroblasts ts MEFs from C57BL/6 mice Protein Western blotting|Mass spectometry 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1885 36063142 Mus musculus Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL Embryonic fibroblasts ts MEFs from C57BL/6 mice Protein Western blotting|Mass spectometry 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1886 36063142 Mus musculus Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL Embryonic fibroblasts ts MEFs from C57BL/6 mice Protein Western blotting|Mass spectometry 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1887 36063142 Mus musculus Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL Embryonic fibroblasts ts MEFs from C57BL/6 mice Protein Western blotting|Mass spectometry 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1888 36063142 Mus musculus Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL Embryonic fibroblasts ts MEFs from C57BL/6 mice Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1889 36063142 Mus musculus Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL Embryonic fibroblasts ts MEFs from C57BL/6 mice Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1890 36063142 Mus musculus Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL Embryonic fibroblasts ts MEFs from C57BL/6 mice Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1891 36063142 Mus musculus Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL Embryonic fibroblasts ts MEFs from C57BL/6 mice Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1892 36063142 Mus musculus Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL Embryonic fibroblasts ts MEFs from C57BL/6 mice Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1893 36063142 Mus musculus Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL Embryonic fibroblasts ts MEFs from C57BL/6 mice Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1894 36063142 Mus musculus Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL Embryonic fibroblasts ts MEFs from C57BL/6 mice Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1895 36063142 Mus musculus Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL Embryonic fibroblasts ts MEFs from C57BL/6 mice Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1896 36260670 Mus musculus Small extracellular vesicles from young adipose-derived stem cells prevent frailty, improve health span, and decrease epigenetic age in old mice Mesenchymal stem cells ts Adipose MSCs from young C57BL/6J mice Protein|miRNA Western blotting|Flow cytometry|Immuno-EM|miRNA array 2022 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 1897 36260670 Mus musculus Small extracellular vesicles from young adipose-derived stem cells prevent frailty, improve health span, and decrease epigenetic age in old mice Mesenchymal stem cells ts Adipose MSCs from old C57BL/6J mice miRNA miRNA array 2022 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 1898 36260670 Mus musculus Small extracellular vesicles from young adipose-derived stem cells prevent frailty, improve health span, and decrease epigenetic age in old mice Plasma ts Old C57BL/6J mice miRNA miRNA array 2022 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 1899 36266345 Homo sapiens Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression Fibroblasts cl MRC-5 Protein Western blotting|Mass spectometry 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1900 36266345 Homo sapiens Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression Fibroblasts cl MRC-5 Protein Western blotting|Mass spectometry 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1901 36266345 Homo sapiens Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression Fibroblasts cl BJ Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1902 36266345 Homo sapiens Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression Fibroblasts cl BJ Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1903 36266345 Homo sapiens Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression Fibroblasts cl MRC-5 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1904 36266345 Homo sapiens Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression Fibroblasts cl MRC-5 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1905 36266345 Homo sapiens Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression Fibroblasts cl MRC-5 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1906 36266345 Homo sapiens Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression Fibroblasts cl MRC-5 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1907 36266345 Homo sapiens Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression Fibroblasts cl MRC-5 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1908 36266345 Homo sapiens Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression Fibroblasts cl MRC-5 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1909 36266345 Homo sapiens Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression Fibroblasts cl MRC-5 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1910 36266345 Homo sapiens Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression Fibroblasts cl MRC-5 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1911 36266345 Homo sapiens Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression Fibroblasts cl MRC-5 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1912 36270983 Mus musculus NLRP6 is required for cancer-derived exosome-modified macrophage M2 polarization and promotes metastasis in small cell lung cancer Lung cancer cells ts Small cell lung cancer (SCLC) Protein Western blotting 2022 Centrifugation|Exosome Isolation Reagent Exosomes 1913 36270983 Mus musculus NLRP6 is required for cancer-derived exosome-modified macrophage M2 polarization and promotes metastasis in small cell lung cancer Lung epithelial cells ts Normal lung epithelium Protein Western blotting 2022 Centrifugation|Exosome Isolation Reagent Exosomes 1914 36303008 Homo sapiens A hydrogel-based mechanical metamaterial for the interferometric profiling of extracellular vesicles in patient samples Colorectal cancer cells cl HCT116 Protein Western blotting|MORPH|ELISA 2023 Filtration|Differential centrifugation|Ultracentrifugation Extracellular vesicles 1915 36303008 Homo sapiens A hydrogel-based mechanical metamaterial for the interferometric profiling of extracellular vesicles in patient samples Colorectal cancer cells cl DLD-1 Protein MORPH|ELISA 2023 Filtration|Differential centrifugation|Ultracentrifugation Extracellular vesicles 1916 36303008 Homo sapiens A hydrogel-based mechanical metamaterial for the interferometric profiling of extracellular vesicles in patient samples Gastric cancer cells cl MKN45 Protein MORPH|ELISA 2023 Filtration|Differential centrifugation|Ultracentrifugation Extracellular vesicles 1917 36303008 Homo sapiens A hydrogel-based mechanical metamaterial for the interferometric profiling of extracellular vesicles in patient samples Gastric cancer cells cl SNU484 Protein MORPH|ELISA 2023 Filtration|Differential centrifugation|Ultracentrifugation Extracellular vesicles 1918 36303008 Homo sapiens A hydrogel-based mechanical metamaterial for the interferometric profiling of extracellular vesicles in patient samples Epidermoid cancer cells cl A431 Protein MORPH|ELISA 2023 Filtration|Differential centrifugation|Ultracentrifugation Extracellular vesicles 1919 36303008 Homo sapiens A hydrogel-based mechanical metamaterial for the interferometric profiling of extracellular vesicles in patient samples Lung cancer cells cl H3255 Protein MORPH|ELISA 2023 Filtration|Differential centrifugation|Ultracentrifugation Extracellular vesicles 1920 36303008 Homo sapiens A hydrogel-based mechanical metamaterial for the interferometric profiling of extracellular vesicles in patient samples Glioma cells cl GLI36 Protein MORPH|ELISA 2023 Filtration|Differential centrifugation|Ultracentrifugation Extracellular vesicles 1921 36303008 Homo sapiens A hydrogel-based mechanical metamaterial for the interferometric profiling of extracellular vesicles in patient samples Lung cancer cells cl PC9 Protein MORPH|ELISA 2023 Filtration|Differential centrifugation|Ultracentrifugation Extracellular vesicles 1922 36253358 Mus musculus Bone marrow mesenchymal stem cell-derived exosomal miR-21a-5p alleviates renal fibrosis by attenuating glycolysis by targeting PFKM Mesenchymal stem cells cl Bone marrow-derived MSCs Protein|miRNA Western blotting|miRNA sequencing|qPCR 2022 Differential centrifugation|Ultracentrifugation Exosomes 1923 36214496 Mus musculus Contaminating transfection complexes can masquerade as small extracellular vesicles and impair their delivery of RNA Motor neuron-like cells cl NSC-34 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 1924 36214496 Mus musculus Contaminating transfection complexes can masquerade as small extracellular vesicles and impair their delivery of RNA Motor neuron-like cells cl NSC-34 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 1925 36214496 Homo sapiens Contaminating transfection complexes can masquerade as small extracellular vesicles and impair their delivery of RNA Embryonic kidney cells cl HEK293 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 1926 36214496 Homo sapiens Contaminating transfection complexes can masquerade as small extracellular vesicles and impair their delivery of RNA Embryonic kidney cells cl HEK293 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 1927 36214496 Homo sapiens Contaminating transfection complexes can masquerade as small extracellular vesicles and impair their delivery of RNA Embryonic kidney cells cl HEK293 - fraction 2 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 1928 36214496 Homo sapiens Contaminating transfection complexes can masquerade as small extracellular vesicles and impair their delivery of RNA Embryonic kidney cells cl HEK293 - fraction 3 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation|OptiPrep density gradient centrifugation Small extracellular vesicles 1929 36214496 Homo sapiens Contaminating transfection complexes can masquerade as small extracellular vesicles and impair their delivery of RNA Embryonic kidney cells cl HEK293 - fraction 4 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation|OptiPrep density gradient centrifugation Small extracellular vesicles 1930 36214496 Homo sapiens Contaminating transfection complexes can masquerade as small extracellular vesicles and impair their delivery of RNA Embryonic kidney cells cl HEK293 - fraction 5 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation|OptiPrep density gradient centrifugation Small extracellular vesicles 1931 36214496 Homo sapiens Contaminating transfection complexes can masquerade as small extracellular vesicles and impair their delivery of RNA Embryonic kidney cells cl HEK293 - fraction 1-2 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 1932 36214496 Homo sapiens Contaminating transfection complexes can masquerade as small extracellular vesicles and impair their delivery of RNA Embryonic kidney cells cl HEK293 - fraction 3-4 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 1933 36103526 Homo sapiens Exosome-mediated delivery of Cas9 ribonucleoprotein complexes for tissue-specific gene therapy of liver diseases Hepatic stellate cells cl LX-2 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Exosomes 1934 36103526 Homo sapiens Exosome-mediated delivery of Cas9 ribonucleoprotein complexes for tissue-specific gene therapy of liver diseases Hepatic stellate cells cl LX-2 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Exosomes 1935 36103526 Homo sapiens Exosome-mediated delivery of Cas9 ribonucleoprotein complexes for tissue-specific gene therapy of liver diseases Hepatic stellate cells cl LX-2 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Exosomes 1936 36103526 Homo sapiens Exosome-mediated delivery of Cas9 ribonucleoprotein complexes for tissue-specific gene therapy of liver diseases Hepatic stellate cells cl LX-2 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Exosomes 1937 36193887 Homo sapiens Machine learning-assisted elucidation of CD81-CD44 interactions in promoting cancer stemness and extracellular vesicle integrity Breast cancer cells cl MDA-MB-231 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1938 36193887 Homo sapiens Machine learning-assisted elucidation of CD81-CD44 interactions in promoting cancer stemness and extracellular vesicle integrity Breast cancer cells cl MDA-MB-231 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1939 36193887 Homo sapiens Machine learning-assisted elucidation of CD81-CD44 interactions in promoting cancer stemness and extracellular vesicle integrity Breast cancer cells cl MDA-MB-231 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1940 36604402 Homo sapiens Identification of faecal extracellular vesicles as novel biomarkers for the non-invasive diagnosis and prognosis of colorectal cancer Faeces ts CRC patient 1 Protein Western blotting|Immuno-EM 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1941 36604402 Homo sapiens Identification of faecal extracellular vesicles as novel biomarkers for the non-invasive diagnosis and prognosis of colorectal cancer Faeces ts CRC patient 2 Protein Western blotting 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1942 36604402 Homo sapiens Identification of faecal extracellular vesicles as novel biomarkers for the non-invasive diagnosis and prognosis of colorectal cancer Faeces ts CRC patient 3 Protein Western blotting 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1943 36604402 Homo sapiens Identification of faecal extracellular vesicles as novel biomarkers for the non-invasive diagnosis and prognosis of colorectal cancer Faeces ts CRC patient 4 Protein Western blotting 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1944 36604402 Homo sapiens Identification of faecal extracellular vesicles as novel biomarkers for the non-invasive diagnosis and prognosis of colorectal cancer Faeces ts Healthy donor 1 Protein Western blotting 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1945 36604402 Homo sapiens Identification of faecal extracellular vesicles as novel biomarkers for the non-invasive diagnosis and prognosis of colorectal cancer Faeces ts Healthy donor 2 Protein Western blotting 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1946 36604402 Homo sapiens Identification of faecal extracellular vesicles as novel biomarkers for the non-invasive diagnosis and prognosis of colorectal cancer Faeces ts Healthy donor 3 Protein Western blotting 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1947 36604402 Homo sapiens Identification of faecal extracellular vesicles as novel biomarkers for the non-invasive diagnosis and prognosis of colorectal cancer Faeces ts Healthy donor 4 Protein Western blotting 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1948 36604402 Homo sapiens Identification of faecal extracellular vesicles as novel biomarkers for the non-invasive diagnosis and prognosis of colorectal cancer Faeces ts Healthy donors Protein ELISA 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1949 36604402 Homo sapiens Identification of faecal extracellular vesicles as novel biomarkers for the non-invasive diagnosis and prognosis of colorectal cancer Faeces ts CRC patients Protein ELISA 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1950 36604402 Homo sapiens Identification of faecal extracellular vesicles as novel biomarkers for the non-invasive diagnosis and prognosis of colorectal cancer Faeces ts CRC patients - Stage I Protein ELISA 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1951 36604402 Homo sapiens Identification of faecal extracellular vesicles as novel biomarkers for the non-invasive diagnosis and prognosis of colorectal cancer Faeces ts CRC patients - Stage II Protein ELISA 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1952 36604402 Homo sapiens Identification of faecal extracellular vesicles as novel biomarkers for the non-invasive diagnosis and prognosis of colorectal cancer Faeces ts CRC patients - Stage III Protein ELISA 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1953 36604402 Homo sapiens Identification of faecal extracellular vesicles as novel biomarkers for the non-invasive diagnosis and prognosis of colorectal cancer Plasma ts Healthy donors Protein ELISA 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1954 36604402 Homo sapiens Identification of faecal extracellular vesicles as novel biomarkers for the non-invasive diagnosis and prognosis of colorectal cancer Plasma ts CRC patients Protein ELISA 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1955 36604402 Homo sapiens Identification of faecal extracellular vesicles as novel biomarkers for the non-invasive diagnosis and prognosis of colorectal cancer Faeces ts CRC patients - Pre-surgery Protein ELISA 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1956 36604402 Homo sapiens Identification of faecal extracellular vesicles as novel biomarkers for the non-invasive diagnosis and prognosis of colorectal cancer Faeces ts CRC patients - Post-surgery Protein ELISA 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 1957 36475545 Homo sapiens Weakly migratory metastatic breast cancer cells activate fibroblasts via microvesicle-Tg2 to facilitate dissemination and metastasis Breast cancer cells cl MDA-MB-231 - weakly migratory (MDA- ) Protein Western blotting|Mass spectometry 2022 Centrifugation|Filtration Microvesicles 1958 36475545 Homo sapiens Weakly migratory metastatic breast cancer cells activate fibroblasts via microvesicle-Tg2 to facilitate dissemination and metastasis Breast cancer cells cl MDA-MB-231 - highly migratory (MDA+) Protein Western blotting|Mass spectometry 2022 Centrifugation|Filtration Microvesicles 1959 36475545 Homo sapiens Weakly migratory metastatic breast cancer cells activate fibroblasts via microvesicle-Tg2 to facilitate dissemination and metastasis Breast cancer cells cl MDA-MB-231 - weakly migratory (MDA- ) Protein Western blotting|Mass spectometry 2022 Centrifugation|Filtration Microvesicles 1960 36475545 Homo sapiens Weakly migratory metastatic breast cancer cells activate fibroblasts via microvesicle-Tg2 to facilitate dissemination and metastasis Breast cancer cells cl MDA-MB-231 - weakly migratory (MDA- ) Protein Western blotting|Mass spectometry 2022 Centrifugation|Filtration Microvesicles 1961 36417505 Homo sapiens A solution to the biophysical fractionation of extracellular vesicles: Acoustic Nanoscale Separation via Wave-pillar Excitation Resonance (ANSWER) Plasma ts Plasma Protein Western blotting 2022 Acoustic nanoscale separation via wave-pillar excitation resonance (ANSWER) Exomeres 1962 36417505 Homo sapiens A solution to the biophysical fractionation of extracellular vesicles: Acoustic Nanoscale Separation via Wave-pillar Excitation Resonance (ANSWER) Plasma ts Plasma Protein Western blotting 2022 Acoustic nanoscale separation via wave-pillar excitation resonance (ANSWER) Exosomes 1963 35915084 Homo sapiens Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Breast cancer cells cl MDA-MB-231 Protein Western blotting|Mass spectometry|Immuno-EM|Flow cytometry|ELISA 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1964 35915084 Homo sapiens Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Breast cancer cells cl MCF10A Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1965 35915084 Homo sapiens Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Breast cancer cells cl MCF7 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1966 35915084 Mus musculus Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Breast cancer cells cl 4T07 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1967 35915084 Mus musculus Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Breast cancer cells cl 4T1 Protein Western blotting|Mass spectometry|Immuno-EM|Flow cytometry|ELISA 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1968 35915084 Homo sapiens Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Breast cancer cells cl MDA-MB-231 - Fraction 5 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation|Sucrose density gradient centrifugation Extracellular vesicles 1969 35915084 Homo sapiens Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Breast cancer cells cl MDA-MB-231 - Fraction 6 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation|Sucrose density gradient centrifugation Extracellular vesicles 1970 35915084 Homo sapiens Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Breast cancer cells cl MDA-MB-231 - Fraction 7 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation|Sucrose density gradient centrifugation Extracellular vesicles 1971 35915084 Homo sapiens Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Breast cancer cells cl MDA-MB-231 - Fraction 8 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation|Sucrose density gradient centrifugation Extracellular vesicles 1972 35915084 Homo sapiens Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Breast cancer cells cl MDA-MB-231 Protein ELISA 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1973 35915084 Mus musculus Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Breast cancer cells cl 4T1 Protein ELISA 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1974 35915084 Homo sapiens Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Plasma ts Healthy donor Protein Flow cytometry|ELISA|Western bloting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1975 35915084 Homo sapiens Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Plasma ts Breast cancer patients - pre-operation Protein Immuno-EM|Flow cytometry|ELISA 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1976 35915084 Homo sapiens Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Plasma ts Breast cancer patients - post operation Protein Immuno-EM|Flow cytometry|ELISA 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1977 35915084 Homo sapiens Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Plasma ts Breast cancer patients - relapse Protein Flow cytometry|ELISA 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1978 35915084 Homo sapiens Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Plasma ts Breast cancer patients Protein Flow cytometry|ELISA|Western bloting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1979 35915084 Homo sapiens Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Plasma ts Breast cancer patients - Luminal A Protein Flow cytometry|ELISA 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1980 35915084 Homo sapiens Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Plasma ts Breast cancer patients - Luminal B Protein Flow cytometry|ELISA 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1981 35915084 Homo sapiens Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Plasma ts Breast cancer patients - HER2+ Protein Flow cytometry|ELISA 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1982 35915084 Homo sapiens Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Plasma ts Breast cancer patients - TNBC Protein Flow cytometry|ELISA 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1983 35915084 Homo sapiens Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Plasma ts Breast cancer patients - no metastasis Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1984 35915084 Homo sapiens Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Plasma ts Breast cancer patients - distant metastasis Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1985 35915084 Homo sapiens Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Breast cancer cells cl MDA-MB-231 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1986 35915084 Homo sapiens Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Breast cancer cells cl MDA-MB-231 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1987 35915084 Homo sapiens Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Breast cancer cells cl MDA-MB-231 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1988 35915084 Homo sapiens Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Breast cancer cells cl MDA-MB-231 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1989 35915084 Homo sapiens Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Breast cancer cells cl MDA-MB-231 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1990 35915084 Homo sapiens Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Breast cancer cells cl MDA-MB-231 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1991 35915084 Homo sapiens Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Breast cancer cells cl MDA-MB-231 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1992 35915084 Homo sapiens Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Breast cancer cells cl MDA-MB-231 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1993 35915084 Homo sapiens Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Breast cancer cells cl MDA-MB-231 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1994 34188787 Mus musculus Arrdc4-dependent extracellular vesicle biogenesis is required for sperm maturation Epididymal epithelial cells ts CBA/CaH male mice Protein Western blotting|Mass spectometry 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1995 34188787 Mus musculus Arrdc4-dependent extracellular vesicle biogenesis is required for sperm maturation Epididymal epithelial cells ts CBA/CaH male mice Protein Western blotting|Mass spectometry 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 1996 34112803 Mus musculus Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution Breast cancer cells cl EO771 Protein Western blotting|Mass spectometry 2021 Differential centrifugation|Filtration|Ultracentrifugation|Size exclusion chromatography|Centrifugal ultrafiltration Exosomes 1997 34112803 Mus musculus Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution Breast cancer cells cl PyMT Protein Western blotting|Mass spectometry 2021 Differential centrifugation|Filtration|Ultracentrifugation|Size exclusion chromatography|Centrifugal ultrafiltration Exosomes 1998 34112803 Homo sapiens Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution Breast cancer cells cl MDA-MB-231 Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation|Size exclusion chromatography|Centrifugal ultrafiltration Exosomes 1999 34112803 Homo sapiens Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution Breast cancer cells cl MCF7 Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation|Size exclusion chromatography|Centrifugal ultrafiltration Exosomes 2000 34112803 Homo sapiens Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution Plasma ts Pooled plasma from healthy subjects and breast cancer patients Protein Western blotting 2021 Size exclusion chromatography|Centrifugal ultrafiltration Exosomes 2001 34112803 Homo sapiens Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution Plasma ts Pooled plasma from healthy subjects Protein ELISA 2021 Size exclusion chromatography|Centrifugal ultrafiltration Exosomes 2002 34112803 Homo sapiens Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution Plasma ts Pooled plasma from breast cancer patients Protein ELISA 2021 Size exclusion chromatography|Centrifugal ultrafiltration Exosomes 2003 34112803 Mus musculus Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution Breast cancer cells cl EO771 Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation|Size exclusion chromatography|Centrifugal ultrafiltration Exosomes 2004 34112803 Mus musculus Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution Breast cancer cells cl EO771 Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation|Size exclusion chromatography|Centrifugal ultrafiltration Exosomes 2005 34112803 Mus musculus Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution Breast cancer cells cl EO771 Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation|Size exclusion chromatography|Centrifugal ultrafiltration Exosomes 2006 34112803 Mus musculus Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution Breast cancer cells cl EO771 Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation|Size exclusion chromatography|Centrifugal ultrafiltration Exosomes 2007 35979935 Homo sapiens Serum-derived extracellular vesicles: Novel biomarkers reflecting the disease severity of COVID-19 patients Serum ts Healthy donors Protein|Lipid Flow cytometry 2022 Differential centrifugation Extracellular vesicles 2008 35979935 Homo sapiens Serum-derived extracellular vesicles: Novel biomarkers reflecting the disease severity of COVID-19 patients Serum ts Severe COVID-19 patients Protein|Lipid Flow cytometry 2022 Differential centrifugation Extracellular vesicles 2009 35979935 Homo sapiens Serum-derived extracellular vesicles: Novel biomarkers reflecting the disease severity of COVID-19 patients Serum ts Mild COVID-19 patients Protein|Lipid Flow cytometry 2022 Differential centrifugation Extracellular vesicles 2010 36417867 Homo sapiens Extracellular vesicles carrying HIV-1 Nef induce long-term hyperreactivity of myeloid cells Embryonic kidney cells cl HEK293T Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2011 36417867 Homo sapiens Extracellular vesicles carrying HIV-1 Nef induce long-term hyperreactivity of myeloid cells Embryonic kidney cells cl HEK293T Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2012 36433666 Homo sapiens Vascular smooth muscle cell senescence accelerates medin aggregation via small extracellular vesicle secretion and extracellular matrix reorganization Vascular smooth muscle cells ts Aorta-derived VSMCs Protein Western blotting 2023 Centrifugation Large extracellular vesicles 2013 36433666 Homo sapiens Vascular smooth muscle cell senescence accelerates medin aggregation via small extracellular vesicle secretion and extracellular matrix reorganization Vascular smooth muscle cells ts Aorta-derived VSMCs Protein Western blotting 2023 Differential centrifugation Medium extracellular vesicles 2014 36433666 Homo sapiens Vascular smooth muscle cell senescence accelerates medin aggregation via small extracellular vesicle secretion and extracellular matrix reorganization Vascular smooth muscle cells ts Aorta-derived VSMCs Protein Western blotting 2023 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2015 36433666 Homo sapiens Vascular smooth muscle cell senescence accelerates medin aggregation via small extracellular vesicle secretion and extracellular matrix reorganization Vascular smooth muscle cells ts Aorta-derived VSMCs Protein Western blotting 2023 Centrifugation Large extracellular vesicles 2016 36433666 Homo sapiens Vascular smooth muscle cell senescence accelerates medin aggregation via small extracellular vesicle secretion and extracellular matrix reorganization Vascular smooth muscle cells ts Aorta-derived VSMCs Protein Western blotting 2023 Differential centrifugation Medium extracellular vesicles 2017 36433666 Homo sapiens Vascular smooth muscle cell senescence accelerates medin aggregation via small extracellular vesicle secretion and extracellular matrix reorganization Vascular smooth muscle cells ts Aorta-derived VSMCs Protein Western blotting 2023 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2018 36433666 Homo sapiens Vascular smooth muscle cell senescence accelerates medin aggregation via small extracellular vesicle secretion and extracellular matrix reorganization Vascular smooth muscle cells ts Aorta-derived VSMCs - early passage Protein Western blotting 2023 Centrifugation Large extracellular vesicles 2019 36433666 Homo sapiens Vascular smooth muscle cell senescence accelerates medin aggregation via small extracellular vesicle secretion and extracellular matrix reorganization Vascular smooth muscle cells ts Aorta-derived VSMCs - early passage Protein Western blotting 2023 Differential centrifugation Medium extracellular vesicles 2020 36433666 Homo sapiens Vascular smooth muscle cell senescence accelerates medin aggregation via small extracellular vesicle secretion and extracellular matrix reorganization Vascular smooth muscle cells ts Aorta-derived VSMCs - early passage Protein Western blotting|Mass spectometry 2023 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2021 36433666 Homo sapiens Vascular smooth muscle cell senescence accelerates medin aggregation via small extracellular vesicle secretion and extracellular matrix reorganization Vascular smooth muscle cells ts Aorta-derived VSMCs - late passage Protein Western blotting 2023 Centrifugation Large extracellular vesicles 2022 36433666 Homo sapiens Vascular smooth muscle cell senescence accelerates medin aggregation via small extracellular vesicle secretion and extracellular matrix reorganization Vascular smooth muscle cells ts Aorta-derived VSMCs - late passage Protein Western blotting 2023 Differential centrifugation Medium extracellular vesicles 2023 36433666 Homo sapiens Vascular smooth muscle cell senescence accelerates medin aggregation via small extracellular vesicle secretion and extracellular matrix reorganization Vascular smooth muscle cells ts Aorta-derived VSMCs - late passage Protein Western blotting|Mass spectometry 2023 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2024 36433666 Homo sapiens Vascular smooth muscle cell senescence accelerates medin aggregation via small extracellular vesicle secretion and extracellular matrix reorganization Osteosarcoma cells cl U2OS Protein Western blotting 2023 Centrifugation Large extracellular vesicles 2025 36433666 Homo sapiens Vascular smooth muscle cell senescence accelerates medin aggregation via small extracellular vesicle secretion and extracellular matrix reorganization Osteosarcoma cells cl U2OS Protein Western blotting 2023 Differential centrifugation Medium extracellular vesicles 2026 36433666 Homo sapiens Vascular smooth muscle cell senescence accelerates medin aggregation via small extracellular vesicle secretion and extracellular matrix reorganization Osteosarcoma cells cl U2OS Protein Western blotting 2023 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2027 36455873 Homo sapiens Sevoflurane-induced POCD-associated exosomes delivered miR-584-5p regulates the growth of human microglia HMC3 cells through targeting BDNF Plasma ts Patients with post-operative cognitive dysfunction (POCD) Protein|miRNA Western blotting|Small RNA sequencing|RT-qPCR 2022 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 2028 36455873 Homo sapiens Sevoflurane-induced POCD-associated exosomes delivered miR-584-5p regulates the growth of human microglia HMC3 cells through targeting BDNF Plasma ts Patients without post-operative cognitive dysfunction (non-POCD) Protein|miRNA Western blotting|Small RNA sequencing|RT-qPCR 2022 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 2029 35986010 Homo sapiens Exosomal miR-155-5p derived from glioma stem-like cells promotes mesenchymal transition via targeting ACOT12 Glioblastoma cells cl U87 Protein|miRNA Western blotting|miRNA sequencing 2022 Centrifugation|Filtration|Ultracentrifugation Exosomes 2030 35986010 Homo sapiens Exosomal miR-155-5p derived from glioma stem-like cells promotes mesenchymal transition via targeting ACOT12 Glial cells cl HEB Protein|miRNA Western blotting|miRNA sequencing 2022 Centrifugation|Filtration|Ultracentrifugation Exosomes 2031 36123372 Homo sapiens Angiocrine extracellular vesicles impose mesenchymal reprogramming upon proneural glioma stem cells Umbilical vein endothelial cells cl HUVEC Protein Western blotting|Mass spectometry 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2032 36123372 Homo sapiens Angiocrine extracellular vesicles impose mesenchymal reprogramming upon proneural glioma stem cells Glioma stem cells cl Proneural-GSC157 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2033 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl LX-2 Protein Western blotting|Mass spectometry 2022 Differential centrifugation Large extracellular vesicles 2034 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl LX-2 Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2035 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl LX-2 Protein Western blotting|Mass spectometry 2022 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2036 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl LX-2 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2037 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl LX-2 Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2038 36192599 Mus musculus HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl moHSCs Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2039 36192599 Mus musculus HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl moHSCs Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2040 36192599 Mus musculus HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells ts Primary HSCs - C57BL/6 liver Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2041 36192599 Mus musculus HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells ts Primary HSCs - C57BL/6 liver Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2042 36192599 Mus musculus HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatocytes ts Primary hepatocytes - C57BL/6 liver Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2043 36192599 Mus musculus HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatocytes ts Primary hepatocytes - C57BL/6 liver Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2044 36192599 Mus musculus HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells ts Primary HSCs - C57BL/6 liver (control) Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2045 36192599 Mus musculus HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells ts Primary HSCs - C57BL/6 liver (induced hepatic fibrosis) Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2046 36192599 Mus musculus HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Fibroblasts ts HCC-associated fibroblasts - C57BL/6 liver (induced HCC) Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2047 36192599 Mus musculus HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Plasma ts Healthy donors Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2048 36192599 Mus musculus HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Plasma ts Liver cirrhosis patients Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2049 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl LX-2 Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2050 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl LX-3 Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2051 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl LX-3 Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2052 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl LX-3 Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2053 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl LX-3 Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2054 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl LX-4 Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2055 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl LX-2 - fraction 4 Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2056 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl LX-2 - fraction 5 Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2057 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl LX-2 - fraction 6 Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2058 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl LX-2 - fraction 4 Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2059 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl LX-2 - fraction 5 Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2060 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl LX-2 - fraction 6 Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2061 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl LX-2 Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2062 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl LX-2 Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2063 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl LX-2 Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2064 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl LX-2 Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2065 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl LX-2 Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2066 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl LX-2 Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2067 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl LX-2 Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2068 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl LX-2 Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2069 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl LX-2 Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2070 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl LX-2 Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2071 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl LX-2 Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2072 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl LX-2 Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2073 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl LX-2 Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2074 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl LX-2 Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2075 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl LX-2 Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2076 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl LX-2 Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2077 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl LX-2 Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2078 36192599 Mus musculus HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl moHSCs Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2079 36192599 Mus musculus HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl moHSCs Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2080 36192599 Mus musculus HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl moHSCs Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2081 36192599 Mus musculus HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl moHSCs Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2082 36192599 Mus musculus HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl moHSCs Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2083 36192599 Mus musculus HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl moHSCs Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2084 36192599 Mus musculus HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Macrophage ts Primary macrophages - C57BL/6 liver (induced hepatic fibrosis) Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2085 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl LX-2 Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2086 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl LX-2 Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2087 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl LX-2 Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2088 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl LX-2 Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2089 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl LX-2 Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2090 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl LX-2 Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2091 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl LX-2 Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2092 36192599 Mus musculus HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells ts Primary HSCs - C57BL/6 liver Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2093 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl LX-2 Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2094 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl LX-2 Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2095 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl LX-2 Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2096 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl LX-2 Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2097 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl LX-2 Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2098 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl LX-2 Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2099 36192599 Homo sapiens HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma Hepatic stellate cells cl LX-2 Protein Western blotting 2022 Differential centrifugation Large extracellular vesicles 2100 36482876 Homo sapiens Suppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels Lung cancer cells cl H1299-fraction 3 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation|Sucrose density gradient centrifugation Small extracellular vesicles 2101 36482876 Homo sapiens Suppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels Lung cancer cells cl H1299-fraction 4 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation|Sucrose density gradient centrifugation Small extracellular vesicles 2102 36482876 Homo sapiens Suppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels Lung cancer cells cl H1299-fraction 5 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation|Sucrose density gradient centrifugation Small extracellular vesicles 2103 36482876 Homo sapiens Suppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels Lung cancer cells cl H1299-fraction 6 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation|Sucrose density gradient centrifugation Small extracellular vesicles 2104 36482876 Homo sapiens Suppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels Lung cancer cells cl H1299 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2105 36482876 Homo sapiens Suppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels Lung cancer cells cl H1299 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2106 36482876 Homo sapiens Suppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels Lung cancer cells cl H1299 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2107 36482876 Homo sapiens Suppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels Lung cancer cells cl H1299 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2108 36482876 Homo sapiens Suppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels Lung cancer cells cl H1299 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2109 36482876 Homo sapiens Suppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels Lung cancer cells cl H1299 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2110 36482876 Mus musculus Suppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels Lung cancer cells cl LLC-1 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2111 36482876 Mus musculus Suppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels Lung cancer cells cl LLC-1 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2112 36482876 Homo sapiens Suppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels Lung cancer cells cl H1299 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2113 36482876 Homo sapiens Suppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels Lung cancer cells cl H1299 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2114 36482876 Homo sapiens Suppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels Lung cancer cells cl H1299 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2115 36482876 Homo sapiens Suppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels Lung cancer cells cl H1975-fraction 3 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation|Sucrose density gradient centrifugation Small extracellular vesicles 2116 36482876 Homo sapiens Suppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels Lung cancer cells cl H1975-fraction 4 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation|Sucrose density gradient centrifugation Small extracellular vesicles 2117 36482876 Homo sapiens Suppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels Lung cancer cells cl H1975-fraction 5 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation|Sucrose density gradient centrifugation Small extracellular vesicles 2118 36482876 Homo sapiens Suppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels Lung cancer cells cl H1975 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2119 36482876 Homo sapiens Suppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels Lung cancer cells cl H1975 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2120 36482876 Homo sapiens Suppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels Lung cancer cells cl H1975 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2121 36482876 Homo sapiens Suppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels Lung cancer cells cl H1975 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2122 36482876 Homo sapiens Suppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels Lung cancer cells cl H1975 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2123 36482876 Homo sapiens Suppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels Lung cancer cells cl H1975 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2124 36482876 Homo sapiens Suppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels Lung cancer cells cl H1975 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2125 36482876 Homo sapiens Suppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels Lung cancer cells cl H1975 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2126 36482876 Homo sapiens Suppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels Lung cancer cells cl H1975 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2127 36649440 Homo sapiens Brain endothelium-derived extracellular vesicles containing amyloid-beta induce mitochondrial alterations in neural progenitor cells Brain endothelial cells cl hCMEC/D3 Protein Western blotting 2022 ExoQuick Kit|Centrifugation Extracellular vesicles 2128 36515353 Homo sapiens Oral nicotinamide riboside raises NAD+ and lowers biomarkers of neurodegenerative pathology in plasma extracellular vesicles enriched for neuronal origin Plasma ts Patient-derived neuronal origin EVs (enriched) Protein Western blotting 2023 ExoQuick Kit|Centrifugation Extracellular vesicles 2129 36515353 Homo sapiens Oral nicotinamide riboside raises NAD+ and lowers biomarkers of neurodegenerative pathology in plasma extracellular vesicles enriched for neuronal origin Plasma ts Patient-derived neuronal origin EVs (total) Protein Western blotting 2023 ExoQuick Kit|Centrifugation Extracellular vesicles 2130 36515353 Homo sapiens Oral nicotinamide riboside raises NAD+ and lowers biomarkers of neurodegenerative pathology in plasma extracellular vesicles enriched for neuronal origin Plasma ts Patient-derived neuronal origin EVs (enriched) Metabolite|Protein Mass spectometry|Luciferase assay|ELISA 2023 ExoQuick Kit|Centrifugation Extracellular vesicles 2131 36515353 Homo sapiens Oral nicotinamide riboside raises NAD+ and lowers biomarkers of neurodegenerative pathology in plasma extracellular vesicles enriched for neuronal origin Plasma ts Patient-derived neuronal origin EVs (enriched) Metabolite|Protein Mass spectometry|Luciferase assay|ELISA 2023 ExoQuick Kit|Centrifugation Extracellular vesicles 2132 36515353 Homo sapiens Oral nicotinamide riboside raises NAD+ and lowers biomarkers of neurodegenerative pathology in plasma extracellular vesicles enriched for neuronal origin Plasma ts Patient-derived neuronal origin EVs (enriched) - responders Metabolite|Protein ELISA 2023 ExoQuick Kit|Centrifugation Extracellular vesicles 2133 36515353 Homo sapiens Oral nicotinamide riboside raises NAD+ and lowers biomarkers of neurodegenerative pathology in plasma extracellular vesicles enriched for neuronal origin Plasma ts Patient-derived neuronal origin EVs (enriched) - responders Metabolite|Protein ELISA 2023 ExoQuick Kit|Centrifugation Extracellular vesicles 2134 36658400 Mus musculus Humoral regulation of iron metabolism by extracellular vesicles drives antibacterial response Serum ts Uninfected Protein Western blotting|Immuno-EM 2023 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2135 36658400 Mus musculus Humoral regulation of iron metabolism by extracellular vesicles drives antibacterial response Serum ts S. typhimurium infected Protein Western blotting|Immuno-EM 2023 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2136 36658400 Mus musculus Humoral regulation of iron metabolism by extracellular vesicles drives antibacterial response Macrophage cl BMDM - S. typhimurium infected Protein Western blotting|Immuno-EM 2023 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2137 36658400 Mus musculus Humoral regulation of iron metabolism by extracellular vesicles drives antibacterial response Macrophage cl BMDM - Uninfected Protein Western blotting|Immuno-EM 2023 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2138 36658400 Mus musculus Humoral regulation of iron metabolism by extracellular vesicles drives antibacterial response Serum ts Serum Protein Western blotting 2023 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2139 36658400 Mus musculus Humoral regulation of iron metabolism by extracellular vesicles drives antibacterial response Macrophage cl BMDM Protein Western blotting 2023 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2140 36658400 Mus musculus Humoral regulation of iron metabolism by extracellular vesicles drives antibacterial response Serum ts Healthy Protein ELISA 2023 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2141 36658400 Mus musculus Humoral regulation of iron metabolism by extracellular vesicles drives antibacterial response Serum ts S. typhimurium infected Protein ELISA 2023 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2142 36658400 Mus musculus Humoral regulation of iron metabolism by extracellular vesicles drives antibacterial response Serum ts S. typhimurium infected Protein Western blotting 2023 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2143 36658400 Mus musculus Humoral regulation of iron metabolism by extracellular vesicles drives antibacterial response Macrophage cl BMDM - S. typhimurium infected Protein Western blotting 2023 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2144 36658400 Mus musculus Humoral regulation of iron metabolism by extracellular vesicles drives antibacterial response Macrophage cl BMDM - S. typhimurium infected Protein Western blotting 2023 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2145 36658400 Mus musculus Humoral regulation of iron metabolism by extracellular vesicles drives antibacterial response Macrophage cl BMDM - S. typhimurium infected Protein Western blotting 2023 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2146 36658400 Mus musculus Humoral regulation of iron metabolism by extracellular vesicles drives antibacterial response Macrophage cl BMDM - S. typhimurium infected Protein Western blotting 2023 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2147 35605283 Escherichia coli Phytochemical Engineered Bacterial Outer Membrane Vesicles for Photodynamic Effects Promoted Immunotherapy Escherichia coli cl E. coli strain MG1655 Protein Western blotting 2022 Centrifugation|Centrifugal ultrafiltration|Filtration|Ultracentrifugation Outer membrane vesicles 2148 35605283 Escherichia coli Phytochemical Engineered Bacterial Outer Membrane Vesicles for Photodynamic Effects Promoted Immunotherapy Escherichia coli cl E. coli strain MG1655 Lipid Western blotting 2022 Centrifugation|Centrifugal ultrafiltration|Filtration|Ultracentrifugation Outer membrane vesicles 2149 35605283 Spinacia oleracea Phytochemical Engineered Bacterial Outer Membrane Vesicles for Photodynamic Effects Promoted Immunotherapy Spinach ts S. oleracea Protein Western blotting 2022 Differential centrifugation|Sonication|Filtration Nanovesicles 2150 34901247 Haemophilus parasuis Proteome Analysis of Outer Membrane Vesicles From a Highly Virulent Strain of Haemophilus parasuis Haemophilus parasuis cl H. parasuis strain H45 Protein Mass spectrometry 2021 Centrifugation|Centrifugal ultrafiltration|Filtration|Ultracentrifugation Outer membrane vesicles 2151 36781972 Pseudomonas aeruginosa The mechanism of Pseudomonas aeruginosa outer membrane vesicle biogenesis determines their protein composition Pseudomonas aeruginosa cl P. aeruginosa strain PAO1 Protein Mass spectrometry 2023 Differential centrifugation|Ultracentrifugation|OptiPrep density gradient centrifugation Outer membrane vesicles 2152 36781972 Pseudomonas aeruginosa The mechanism of Pseudomonas aeruginosa outer membrane vesicle biogenesis determines their protein composition Pseudomonas aeruginosa cl P. aeruginosa strain PAO1 Protein Mass spectrometry 2023 Differential centrifugation|Ultracentrifugation|OptiPrep density gradient centrifugation Outer membrane vesicles 2153 36781972 Pseudomonas aeruginosa The mechanism of Pseudomonas aeruginosa outer membrane vesicle biogenesis determines their protein composition Pseudomonas aeruginosa cl P. aeruginosa strain PAO1 Protein Mass spectrometry 2023 Differential centrifugation|Ultracentrifugation|OptiPrep density gradient centrifugation Outer membrane vesicles 2154 30488570 Helicobacter pylori Helicobacter pylori Growth Stage Determines the Size, Protein Composition, and Preferential Cargo Packaging of Outer Membrane Vesicles Helicobacter pylori cl H. pylori strain 26695 - 16 h - Early log phase Protein Mass spectrometry 2019 Differential centrifugation|Ultracentrifugation|OptiPrep density gradient centrifugation Outer membrane vesicles 2155 30488570 Helicobacter pylori Helicobacter pylori Growth Stage Determines the Size, Protein Composition, and Preferential Cargo Packaging of Outer Membrane Vesicles Helicobacter pylori cl H. pylori strain 26695 - 48 h - Late log phase Protein Mass spectrometry 2019 Differential centrifugation|Ultracentrifugation|OptiPrep density gradient centrifugation Outer membrane vesicles 2156 30488570 Helicobacter pylori Helicobacter pylori Growth Stage Determines the Size, Protein Composition, and Preferential Cargo Packaging of Outer Membrane Vesicles Helicobacter pylori cl H. pylori strain 26695 - 72 h - Stationary phase Protein Mass spectrometry 2019 Differential centrifugation|Ultracentrifugation|OptiPrep density gradient centrifugation Outer membrane vesicles 2157 34140472 Amblyomma americanum Tick extracellular vesicles enable arthropod feeding and promote distinct outcomes of bacterial infection Amblyomma americanum cl AAE2 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2158 34140472 Ixodes scapularis Tick extracellular vesicles enable arthropod feeding and promote distinct outcomes of bacterial infection Ixodes scapularis cl ISE6 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2159 34140472 Dermacentor andersoni Tick extracellular vesicles enable arthropod feeding and promote distinct outcomes of bacterial infection Dermacentor andersoni cl DAE100 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2160 34140472 Ixodes scapularis Tick extracellular vesicles enable arthropod feeding and promote distinct outcomes of bacterial infection Salivary glands ts Salivary glands Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2161 34140472 Ixodes scapularis Tick extracellular vesicles enable arthropod feeding and promote distinct outcomes of bacterial infection Ixodes scapularis cl IDE12 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2162 34140472 Ixodes ricinus Tick extracellular vesicles enable arthropod feeding and promote distinct outcomes of bacterial infection Saliva ts Saliva Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2163 34140472 Homo sapiens Tick extracellular vesicles enable arthropod feeding and promote distinct outcomes of bacterial infection Leukemia cells cl HL-60 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2164 34140472 Ixodes scapularis Tick extracellular vesicles enable arthropod feeding and promote distinct outcomes of bacterial infection Ixodes scapularis cl ISE6 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2165 34140472 Ixodes scapularis Tick extracellular vesicles enable arthropod feeding and promote distinct outcomes of bacterial infection Salivary glands ts Salivary glands Protein Mass spectrometry 2021 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 2166 35674493 Aeromonas hydrophila Quantitative Proteomics Reveals That the Protein Components of Outer Membrane Vesicles (OMVs) in Aeromonas hydrophila Play Protective Roles in Antibiotic Resistance Aeromonas hydrophila cl A. hydrophila - Oxytetracycline-sensitive Protein Mass spectrometry 2022 Differential centrifugation|Ultracentrifugation Outer membrane vesicles 2167 35674493 Aeromonas hydrophila Quantitative Proteomics Reveals That the Protein Components of Outer Membrane Vesicles (OMVs) in Aeromonas hydrophila Play Protective Roles in Antibiotic Resistance Aeromonas hydrophila cl A. hydrophila - Oxytetracycline-resistant Protein Mass spectrometry 2022 Differential centrifugation|Ultracentrifugation Outer membrane vesicles 2168 29643357 Staphylococcus aureus Release of Staphylococcus aureus extracellular vesicles and their application as a vaccine platform Staphylococcus aureus cl S. aureus strain JE2 Protein Mass spectrometry 2018 Filtration|Tangential flow filtration|OptiPrep density gradient centrifugation|Ultracentrifugation|Centrifugal ultrafiltration Extracellular vesicles 2169 29643357 Staphylococcus aureus Release of Staphylococcus aureus extracellular vesicles and their application as a vaccine platform Staphylococcus aureus cl S. aureus strain JE2 Protein Mass spectrometry 2018 Filtration|Tangential flow filtration|OptiPrep density gradient centrifugation|Ultracentrifugation|Centrifugal ultrafiltration Extracellular vesicles 2170 29643357 Staphylococcus aureus Release of Staphylococcus aureus extracellular vesicles and their application as a vaccine platform Staphylococcus aureus cl S. aureus strain JE2 Protein Western blotting 2018 Filtration|Tangential flow filtration|OptiPrep density gradient centrifugation|Ultracentrifugation|Centrifugal ultrafiltration Extracellular vesicles 2171 29643357 Staphylococcus aureus Release of Staphylococcus aureus extracellular vesicles and their application as a vaccine platform Staphylococcus aureus cl S. aureus strain JE2 Protein Western blotting 2018 Filtration|Tangential flow filtration|OptiPrep density gradient centrifugation|Ultracentrifugation|Centrifugal ultrafiltration Extracellular vesicles 2172 30536591 Homo sapiens A Combination of Proteomic Approaches Identifies A Panel of Circulating Extracellular Vesicle Proteins Related to the Risk of Suffering Cardiovascular Disease in Obese Patients Plasma ts Obese Protein Mass spectrometry|Western blotting 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2173 30536591 Homo sapiens A Combination of Proteomic Approaches Identifies A Panel of Circulating Extracellular Vesicle Proteins Related to the Risk of Suffering Cardiovascular Disease in Obese Patients Plasma ts Lean (control) Protein Mass spectrometry|Western blotting 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2174 34276573 Escherichia coli Differential Packaging Into Outer Membrane Vesicles Upon Oxidative Stress Reveals a General Mechanism for Cargo Selectivity Escherichia coli cl E. coli strain ETEC H10407 Protein Mass spectrometry 2021 Differential centrifugation|Ultracentrifugation Outer membrane vesicles 2175 34276573 Escherichia coli Differential Packaging Into Outer Membrane Vesicles Upon Oxidative Stress Reveals a General Mechanism for Cargo Selectivity Escherichia coli cl E. coli strain ETEC H10407 Protein Mass spectrometry 2021 Differential centrifugation|Ultracentrifugation Outer membrane vesicles 2176 34276573 Escherichia coli Differential Packaging Into Outer Membrane Vesicles Upon Oxidative Stress Reveals a General Mechanism for Cargo Selectivity Escherichia coli cl E. coli strain BL21 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Outer membrane vesicles 2177 34276573 Escherichia coli Differential Packaging Into Outer Membrane Vesicles Upon Oxidative Stress Reveals a General Mechanism for Cargo Selectivity Escherichia coli cl E. coli strain BL21 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Outer membrane vesicles 2178 34276573 Escherichia coli Differential Packaging Into Outer Membrane Vesicles Upon Oxidative Stress Reveals a General Mechanism for Cargo Selectivity Escherichia coli cl E. coli strain BL21 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Outer membrane vesicles 2179 34276573 Escherichia coli Differential Packaging Into Outer Membrane Vesicles Upon Oxidative Stress Reveals a General Mechanism for Cargo Selectivity Escherichia coli cl E. coli strain BL21 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Outer membrane vesicles 2180 34276573 Escherichia coli Differential Packaging Into Outer Membrane Vesicles Upon Oxidative Stress Reveals a General Mechanism for Cargo Selectivity Escherichia coli cl E. coli strain BL21 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Outer membrane vesicles 2181 34276573 Escherichia coli Differential Packaging Into Outer Membrane Vesicles Upon Oxidative Stress Reveals a General Mechanism for Cargo Selectivity Escherichia coli cl E. coli strain BL21 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Outer membrane vesicles 2182 34276573 Escherichia coli Differential Packaging Into Outer Membrane Vesicles Upon Oxidative Stress Reveals a General Mechanism for Cargo Selectivity Escherichia coli cl E. coli strain BL21 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Outer membrane vesicles 2183 34276573 Escherichia coli Differential Packaging Into Outer Membrane Vesicles Upon Oxidative Stress Reveals a General Mechanism for Cargo Selectivity Escherichia coli cl E. coli strain BL21 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Outer membrane vesicles 2184 34276573 Escherichia coli Differential Packaging Into Outer Membrane Vesicles Upon Oxidative Stress Reveals a General Mechanism for Cargo Selectivity Escherichia coli cl E. coli strain BL21 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Outer membrane vesicles 2185 34276573 Escherichia coli Differential Packaging Into Outer Membrane Vesicles Upon Oxidative Stress Reveals a General Mechanism for Cargo Selectivity Escherichia coli cl E. coli strain BL21 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Outer membrane vesicles 2186 33792189 Mus musculus A novel role for milk fat globule-EGF factor 8 protein (MFGE8) in the mediation of mouse sperm-extracellular vesicle interactions Epididymal epithelial cells cl mECap18 - Fraction 9 Protein Western blotting 2021 Filtration|Tangential flow filtration|OptiPrep density gradient centrifugation|Ultracentrifugation|Centrifugal ultrafiltration Extracellular vesicles 2187 33792189 Mus musculus A novel role for milk fat globule-EGF factor 8 protein (MFGE8) in the mediation of mouse sperm-extracellular vesicle interactions Epididymal epithelial cells cl mECap18 - Fraction 10 Protein Western blotting 2021 Filtration|Tangential flow filtration|OptiPrep density gradient centrifugation|Ultracentrifugation|Centrifugal ultrafiltration Extracellular vesicles 2188 33792189 Mus musculus A novel role for milk fat globule-EGF factor 8 protein (MFGE8) in the mediation of mouse sperm-extracellular vesicle interactions Epididymal epithelial cells cl mECap18 - Fraction 9 Protein Western blotting 2021 Filtration|Tangential flow filtration|OptiPrep density gradient centrifugation|Ultracentrifugation|Centrifugal ultrafiltration Extracellular vesicles 2189 33792189 Mus musculus A novel role for milk fat globule-EGF factor 8 protein (MFGE8) in the mediation of mouse sperm-extracellular vesicle interactions Epididymal fluid ts Epididymal fluid Protein Western blotting 2021 Differential centrifugation|OptiPrep density gradient centrifugation|Ultracentrifugation Epididymosomes 2190 36592640 Escherichia coli Outer membrane vesicles from Escherichia coli are efficiently internalized by macrophage cells and alter their inflammatory response Escherichia coli E. coli - pateint sputum Protein Mass spectrometry 2023 Differential centrifugation|Ultracentrifugation Outer membrane vesicles 2191 36592640 Escherichia coli Outer membrane vesicles from Escherichia coli are efficiently internalized by macrophage cells and alter their inflammatory response Escherichia coli E. coli - pateint sputum Lipid ELISA 2023 Differential centrifugation|Ultracentrifugation Outer membrane vesicles 2192 35229476 Lactococcus lactis Extracellular vesicle formation in Lactococcus lactis is stimulated by prophage-encoded holin-lysin system Lactococcus lactis L. lactis strain FM-YL11 ssp. cremoris - Prophage inducing conditions Protein Mass spectrometry 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2193 29511463 Bos taurus Biocompatibility of highly purified bovine milk-derived extracellular vesicles Bovine milk ts Commercial milk - deffated Protein Western blotting 2018 Acidification|Differential centrifugation|Ultracentrifugation Extracellular vesicles 2194 29511463 Bos taurus Biocompatibility of highly purified bovine milk-derived extracellular vesicles Bovine milk ts Commercial milk - deffated Protein Western blotting 2018 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2195 29511463 Bos taurus Biocompatibility of highly purified bovine milk-derived extracellular vesicles Bovine milk ts Commercial milk - deffated Protein Mass spectrometry 2018 Acidification|Differential centrifugation|Ultracentrifugation Extracellular vesicles 2196 29511463 Bos taurus Biocompatibility of highly purified bovine milk-derived extracellular vesicles Bovine milk ts Commercial milk - deffated Protein Mass spectrometry 2018 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2197 33828139 Bos taurus Extracellular vesicles isolated from milk can improve gut barrier dysfunction induced by malnutrition Bovine milk ts Unpasteurized Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation|OptiPrep density gradient centrifugation Extracellular vesicles 2198 33732416 Homo sapiens Human milk extracellular vesicles target nodes in interconnected signalling pathways that enhance oral epithelial barrier function and dampen immune responses Breast milk ts Eluate 1 Protein Western blotting 2021 Differential centrifugation|OptiPrep density gradient centrifugation|Size exclusion chromatography Extracellular vesicles 2199 33732416 Homo sapiens Human milk extracellular vesicles target nodes in interconnected signalling pathways that enhance oral epithelial barrier function and dampen immune responses Breast milk ts Eluate 2 Protein Western blotting 2021 Differential centrifugation|OptiPrep density gradient centrifugation|Size exclusion chromatography Extracellular vesicles 2200 33732416 Homo sapiens Human milk extracellular vesicles target nodes in interconnected signalling pathways that enhance oral epithelial barrier function and dampen immune responses Breast milk ts Eluate 3 Protein Western blotting 2021 Differential centrifugation|OptiPrep density gradient centrifugation|Size exclusion chromatography Extracellular vesicles 2201 33732416 Homo sapiens Human milk extracellular vesicles target nodes in interconnected signalling pathways that enhance oral epithelial barrier function and dampen immune responses Breast milk ts Eluate 4 Protein Western blotting 2021 Differential centrifugation|OptiPrep density gradient centrifugation|Size exclusion chromatography Extracellular vesicles 2202 33732416 Homo sapiens Human milk extracellular vesicles target nodes in interconnected signalling pathways that enhance oral epithelial barrier function and dampen immune responses Breast milk ts Eluate 5 Protein Western blotting 2021 Differential centrifugation|OptiPrep density gradient centrifugation|Size exclusion chromatography Extracellular vesicles 2203 33732416 Homo sapiens Human milk extracellular vesicles target nodes in interconnected signalling pathways that enhance oral epithelial barrier function and dampen immune responses Breast milk ts Eluate 6 Protein Western blotting 2021 Differential centrifugation|OptiPrep density gradient centrifugation|Size exclusion chromatography Extracellular vesicles 2204 33732416 Homo sapiens Human milk extracellular vesicles target nodes in interconnected signalling pathways that enhance oral epithelial barrier function and dampen immune responses Breast milk ts Eluate 7 Protein Western blotting 2021 Differential centrifugation|OptiPrep density gradient centrifugation|Size exclusion chromatography Extracellular vesicles 2205 33732416 Homo sapiens Human milk extracellular vesicles target nodes in interconnected signalling pathways that enhance oral epithelial barrier function and dampen immune responses Breast milk ts Eluate 8 Protein Western blotting 2021 Differential centrifugation|OptiPrep density gradient centrifugation|Size exclusion chromatography Extracellular vesicles 2206 33732416 Homo sapiens Human milk extracellular vesicles target nodes in interconnected signalling pathways that enhance oral epithelial barrier function and dampen immune responses Breast milk ts Eluate 9 Protein Western blotting 2021 Differential centrifugation|OptiPrep density gradient centrifugation|Size exclusion chromatography Extracellular vesicles 2207 36013250 Escherichia coli Proteomic Profiling of Outer Membrane Vesicles Released by Escherichia coli LPS Mutants Defective in Heptose Biosynthesis Escherichia coli cl E. coli strain BW25113 Protein Mass spectrometry 2022 Differential centrifugation|Ultracentrifugation Outer membrane vesicles 2208 36013250 Escherichia coli Proteomic Profiling of Outer Membrane Vesicles Released by Escherichia coli LPS Mutants Defective in Heptose Biosynthesis Escherichia coli cl E. coli strain BW25113 Protein Mass spectrometry 2022 Differential centrifugation|Ultracentrifugation Outer membrane vesicles 2209 36013250 Escherichia coli Proteomic Profiling of Outer Membrane Vesicles Released by Escherichia coli LPS Mutants Defective in Heptose Biosynthesis Escherichia coli cl E. coli strain BW25113 Protein Mass spectrometry 2022 Differential centrifugation|Ultracentrifugation Outer membrane vesicles 2210 36013250 Escherichia coli Proteomic Profiling of Outer Membrane Vesicles Released by Escherichia coli LPS Mutants Defective in Heptose Biosynthesis Escherichia coli cl E. coli strain BW25113 Mass spectrometry 2022 Differential centrifugation|Ultracentrifugation Outer membrane vesicles 2211 37043568 Bos taurus Milk-derived extracellular vesicles protect intestinal barrier integrity in the gut-liver axis Bovine milk ts Colostrum Protein Western blotting 2023 Differential centrifugation|Ultracentrifugation|Centrifugal ultrafiltration Extracellular vesicles 2212 37043568 Homo sapiens Milk-derived extracellular vesicles protect intestinal barrier integrity in the gut-liver axis Breast milk ts Colostrum Protein Western blotting 2023 Differential centrifugation|Ultracentrifugation|Centrifugal ultrafiltration Extracellular vesicles 2213 37043568 Bos taurus Milk-derived extracellular vesicles protect intestinal barrier integrity in the gut-liver axis Bovine milk ts Colostrum miRNA RNA sequencing 2023 Differential centrifugation|Ultracentrifugation|Centrifugal ultrafiltration Extracellular vesicles 2214 37043568 Homo sapiens Milk-derived extracellular vesicles protect intestinal barrier integrity in the gut-liver axis Breast milk ts Colostrum miRNA RNA sequencing 2023 Differential centrifugation|Ultracentrifugation|Centrifugal ultrafiltration Extracellular vesicles 2215 35953855 Bos taurus Milk-derived small extracellular vesicles: nanomaterials to promote bone formation Bovine milk ts Milk Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2217 35753600 Mus musculus Outer membrane vesicles derived from heatstroke-associated intestinal microbiota promote multiple organ injury in mice Faeces ts Faeces - C57BL/6J Protein Western blotting 2022 Differential centrifugation|Iodixanol density gradient centrifugation Outer membrane vesicles 2218 35753600 Mus musculus Outer membrane vesicles derived from heatstroke-associated intestinal microbiota promote multiple organ injury in mice Faeces ts Faeces - C57BL/6J Protein Western blotting 2022 Differential centrifugation|Iodixanol density gradient centrifugation Outer membrane vesicles 2219 32854612 Escherichia coli Probiotic Escherichia coli Nissle 1917-derived outer membrane vesicles enhance immunomodulation and antimicrobial activity in RAW264.7 macrophages Escherichia coli cl E. coli strain Nissle 1917 Protein Mass spectrometry 2020 Centrifugation|Filtration|Centrifugal ultrafiltration|Ultracentrifugation|OptiPrep density gradient centrifugation Outer membrane vesicles 2220 31493501 Klebsiella pneumoniae Isolation, characterization and analysis of pro-inflammatory potential of Klebsiella pneumoniae outer membrane vesicles Klebsiella pneumoniae cl K. pneumoniae Protein Mass spectrometry 2019 Differential centrifugation|Ultracentrifugation Outer membrane vesicles 2221 34596356 Homo sapiens Stroma-derived extracellular vesicle mRNA signatures inform histological nature of prostate cancer Primary prostate stromal cells ts Tumor-associated Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2222 34596356 Homo sapiens Stroma-derived extracellular vesicle mRNA signatures inform histological nature of prostate cancer Primary prostate stromal cells ts Normal Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2223 34596356 Homo sapiens Stroma-derived extracellular vesicle mRNA signatures inform histological nature of prostate cancer Primary prostate stromal cells ts Tumor-associated Protein Fluorescence immunoassay 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2224 34596356 Homo sapiens Stroma-derived extracellular vesicle mRNA signatures inform histological nature of prostate cancer Primary prostate stromal cells ts Normal Protein Fluorescence immunoassay 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2225 34596356 Homo sapiens Stroma-derived extracellular vesicle mRNA signatures inform histological nature of prostate cancer Primary prostate stromal cells ts Tumor-associated mRNA RT-qPCR 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2226 34596356 Homo sapiens Stroma-derived extracellular vesicle mRNA signatures inform histological nature of prostate cancer Primary prostate stromal cells ts Normal mRNA RT-qPCR 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2227 32494663 Homo sapiens miR-26a regulates extracellular vesicle secretion from prostate cancer cells via targeting SHC4, PFDN4, and CHORDC1 Pancreatic cancer cells cl PC3M-luc-C6 Protein Western blotting 2020 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2228 32494663 Homo sapiens miR-26a regulates extracellular vesicle secretion from prostate cancer cells via targeting SHC4, PFDN4, and CHORDC1 Pancreatic cancer cells cl PC3 Protein Western blotting 2020 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2229 36648227 Mus musculus Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Macrophage cl RAW264.2 Protein Western blotting 2023 Differential centrifugation|Ultracentrifugation Exosomes 2230 36648227 Mus musculus Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Macrophage cl RAW264.2 - E. coli infected Protein Western blotting 2023 Differential centrifugation|Ultracentrifugation Exosomes 2231 36648227 Mus musculus Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Macrophage cl RAW264.2 - E. coli infected Protein Western blotting 2023 Differential centrifugation|Ultracentrifugation Exosomes 2232 36648227 Escherichia coli Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Escherichia coli cl E. coli strain DH5α - 9h culture Protein Western blotting 2023 Differential centrifugation|Ultracentrifugation Exosomes 2233 36648227 Escherichia coli Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Escherichia coli cl E. coli strain DH5α - 12h culture Protein Western blotting 2023 Differential centrifugation|Ultracentrifugation Exosomes 2234 36648227 Escherichia coli Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Escherichia coli cl E. coli strain DH5α - 18h culture Protein Western blotting 2023 Differential centrifugation|Ultracentrifugation Exosomes 2235 36648227 Escherichia coli Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Escherichia coli cl E. coli strain DH5α - 24h culture Protein Western blotting 2023 Differential centrifugation|Ultracentrifugation Exosomes 2236 36648227 Escherichia coli Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Escherichia coli cl E. coli strain BL21 (ClearColi) - 18h culture Protein Western blotting 2023 Differential centrifugation|Ultracentrifugation Exosomes 2237 36648227 Escherichia coli Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Escherichia coli cl E. coli strain BL21 (ClearColi) - 21h culture Protein Western blotting 2023 Differential centrifugation|Ultracentrifugation Exosomes 2238 36648227 Escherichia coli Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Escherichia coli cl E. coli strain BL21 (ClearColi) - 24h culture Protein Western blotting 2023 Differential centrifugation|Ultracentrifugation Exosomes 2239 36648227 Escherichia coli Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Escherichia coli cl E. coli strain BL21 (ClearColi) - 27h culture Protein Western blotting 2023 Differential centrifugation|Ultracentrifugation Exosomes 2240 36648227 Mus musculus Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Macrophage cl BMDM Protein Western blotting 2023 Differential centrifugation|Ultracentrifugation Exosomes 2241 36648227 Mus musculus Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Macrophage cl BMDM Protein Western blotting 2023 Differential centrifugation|Ultracentrifugation Exosomes 2242 36648227 Mus musculus Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Macrophage cl RAW264.2 Protein Mass spetrometry 2023 Differential centrifugation|Ultracentrifugation Exosomes 2243 36648227 Escherichia coli Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Escherichia coli cl E. coli strain K-12 BW25113 - Fraction 5 Protein Western blotting 2023 Differential centrifugation|Ultracentrifugation|OptiPrep density gradient centrifugation Exosomes 2244 36648227 Escherichia coli Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Escherichia coli cl E. coli strain K-12 BW25113 - Fraction 6 Protein Western blotting 2023 Differential centrifugation|Ultracentrifugation|OptiPrep density gradient centrifugation Exosomes 2245 36648227 Escherichia coli Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Escherichia coli cl E. coli strain K-12 BW25113 - Fraction 7 Protein Western blotting 2023 Differential centrifugation|Ultracentrifugation|OptiPrep density gradient centrifugation Exosomes 2246 36648227 Escherichia coli Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Escherichia coli cl E. coli strain K-12 BW25113 - Fraction 8 Protein Western blotting 2023 Differential centrifugation|Ultracentrifugation|OptiPrep density gradient centrifugation Exosomes 2247 36648227 Escherichia coli Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Escherichia coli cl E. coli strain K-12 BW25113 - Fraction 9 Protein Western blotting 2023 Differential centrifugation|Ultracentrifugation|OptiPrep density gradient centrifugation Exosomes 2248 36648227 Escherichia coli Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Escherichia coli cl E. coli strain K-12 BW25113 - Fraction 10 Protein Western blotting 2023 Differential centrifugation|Ultracentrifugation|OptiPrep density gradient centrifugation Exosomes 2249 36648227 Escherichia coli Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Escherichia coli cl E. coli strain K-12 BW25113 - Fraction 11 Protein Western blotting 2023 Differential centrifugation|Ultracentrifugation|OptiPrep density gradient centrifugation Exosomes 2250 36648227 Escherichia coli Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Escherichia coli cl E. coli strain K-12 BW25113 - Fraction 12 Protein Western blotting 2023 Differential centrifugation|Ultracentrifugation|OptiPrep density gradient centrifugation Exosomes 2251 36648227 Escherichia coli Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Escherichia coli cl E. coli strain K-12 BW25113 Protein Western blotting 2023 Differential centrifugation|Ultracentrifugation|OptiPrep density gradient centrifugation Exosomes 2252 36648227 Escherichia coli Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Escherichia coli cl E. coli strain K-12 BW25113 Protein Western blotting 2023 Differential centrifugation|Ultracentrifugation|OptiPrep density gradient centrifugation Exosomes 2253 36648227 Escherichia coli Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Escherichia coli cl E. coli strain K-12 BW25113 Protein Western blotting 2023 Differential centrifugation|Ultracentrifugation|OptiPrep density gradient centrifugation Exosomes 2254 36648227 Escherichia coli Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Escherichia coli cl E. coli strain K-12 BW25113 Protein Western blotting 2023 Differential centrifugation|Ultracentrifugation|OptiPrep density gradient centrifugation Exosomes 2255 36648227 Escherichia coli Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Escherichia coli cl E. coli strain K-12 BW25113 Protein Western blotting 2023 Differential centrifugation|Ultracentrifugation|OptiPrep density gradient centrifugation Exosomes 2256 36648227 Escherichia coli Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Escherichia coli cl E. coli strain K-12 BW25113 Protein Western blotting 2023 Differential centrifugation|Ultracentrifugation|OptiPrep density gradient centrifugation Exosomes 2257 36648227 Escherichia coli Escherichia coli-Derived Outer Membrane Vesicles Relay Inflammatory Responses to Macrophage-Derived Exosomes Escherichia coli cl E. coli strain K-12 BW25113 Protein Western blotting 2023 Differential centrifugation|Ultracentrifugation|OptiPrep density gradient centrifugation Exosomes 2258 37376799 Bos taurus Bovine milk-derived extracellular vesicles enhance doxorubicin sensitivity in triple negative breast cancer cells by targeting metabolism and STAT signalling Bovine milk ts Commercial milk Protein Western blotting 2023 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2259 35661560 Homo sapiens Exercise increases the release of NAMPT in extracellular vesicles and alters NAD+ activity in recipient cells Plasma ts Plamsa - Young and unfit Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2260 35661560 Homo sapiens Exercise increases the release of NAMPT in extracellular vesicles and alters NAD+ activity in recipient cells Plasma ts Plamsa - Young and unfit Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2261 35661560 Homo sapiens Exercise increases the release of NAMPT in extracellular vesicles and alters NAD+ activity in recipient cells Plasma ts Plamsa - Young and fit Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2262 35661560 Homo sapiens Exercise increases the release of NAMPT in extracellular vesicles and alters NAD+ activity in recipient cells Plasma ts Plamsa - Young and fit Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2263 35661560 Homo sapiens Exercise increases the release of NAMPT in extracellular vesicles and alters NAD+ activity in recipient cells Plasma ts Plamsa - Mature and unfit Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2264 35661560 Homo sapiens Exercise increases the release of NAMPT in extracellular vesicles and alters NAD+ activity in recipient cells Plasma ts Plamsa - Mature and unfit Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2265 35661560 Homo sapiens Exercise increases the release of NAMPT in extracellular vesicles and alters NAD+ activity in recipient cells Plasma ts Plamsa - Mature and fit Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2266 35661560 Homo sapiens Exercise increases the release of NAMPT in extracellular vesicles and alters NAD+ activity in recipient cells Plasma ts Plamsa - Mature and fit Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2267 36624553 Homo sapiens Combination of size-exclusion chromatography and ion exchange adsorption for improving the proteomic analysis of plasma-derived extracellular vesicles Plasma ts Plasma Protein Western blotting|Mass spectrometry 2023 Filtration|Size exclusion chromatography|Centrifugal ultrafiltration Extracellular vesicles 2268 36624553 Homo sapiens Combination of size-exclusion chromatography and ion exchange adsorption for improving the proteomic analysis of plasma-derived extracellular vesicles Plasma ts Plasma - Ion exchange adsorption 12.5 mg Protein Western blotting|Mass spectrometry 2023 Filtration|Size exclusion chromatography|Ion exchange adsorption|Centrifugation|Centrifugal ultrafiltration Small extracellular vesicles 2269 36624553 Homo sapiens Combination of size-exclusion chromatography and ion exchange adsorption for improving the proteomic analysis of plasma-derived extracellular vesicles Plasma ts Plasma - Ion exchange adsorption 25 mg Protein Western blotting|Mass spectrometry 2023 Filtration|Size exclusion chromatography|Ion exchange adsorption|Centrifugation|Centrifugal ultrafiltration Small extracellular vesicles 2270 36624553 Homo sapiens Combination of size-exclusion chromatography and ion exchange adsorption for improving the proteomic analysis of plasma-derived extracellular vesicles Plasma ts Plasma - Esophageal cancer Protein Mass spectrometry 2023 Filtration|Size exclusion chromatography|Centrifugal ultrafiltration Small extracellular vesicles 2271 36624553 Homo sapiens Combination of size-exclusion chromatography and ion exchange adsorption for improving the proteomic analysis of plasma-derived extracellular vesicles Plasma ts Plasma - Lung cancer Protein Mass spectrometry 2023 Filtration|Size exclusion chromatography|Centrifugal ultrafiltration Small extracellular vesicles 2272 36624553 Homo sapiens Combination of size-exclusion chromatography and ion exchange adsorption for improving the proteomic analysis of plasma-derived extracellular vesicles Plasma ts Plasma - Breast cancer Protein Mass spectrometry 2023 Filtration|Size exclusion chromatography|Centrifugal ultrafiltration Small extracellular vesicles 2273 36624553 Homo sapiens Combination of size-exclusion chromatography and ion exchange adsorption for improving the proteomic analysis of plasma-derived extracellular vesicles Plasma ts Plasma - Esophageal cancer - Ion exchange adsorption 25 mg Protein Mass spectrometry 2023 Filtration|Size exclusion chromatography|Ion exchange adsorption|Centrifugation|Centrifugal ultrafiltration Small extracellular vesicles 2274 36624553 Homo sapiens Combination of size-exclusion chromatography and ion exchange adsorption for improving the proteomic analysis of plasma-derived extracellular vesicles Plasma ts Plasma - Lung cancer - Ion exchange adsorption 25 mg Protein Mass spectrometry 2023 Filtration|Size exclusion chromatography|Ion exchange adsorption|Centrifugation|Centrifugal ultrafiltration Small extracellular vesicles 2275 36624553 Homo sapiens Combination of size-exclusion chromatography and ion exchange adsorption for improving the proteomic analysis of plasma-derived extracellular vesicles Plasma ts Plasma - Breast cancer - Ion exchange adsorption 25 mg Protein Mass spectrometry 2023 Filtration|Size exclusion chromatography|Ion exchange adsorption|Centrifugation|Centrifugal ultrafiltration Small extracellular vesicles 2276 29295981 Homo sapiens Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis Plasma ts Healthy controls Protein|miRNA Western blotting|Microarray|RT-qPCR 2018 Differential centrifugation|Polyethylene glycol-based precipitation|Centrifugation Exosomes 2277 29295981 Homo sapiens Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis Plasma ts Multiple sclerosis miRNA Microarray|RT-qPCR 2018 Differential centrifugation|Polyethylene glycol-based precipitation|Centrifugation Exosomes 2278 29295981 Homo sapiens Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis Plasma ts Relapsing-remitting multiple sclerosis miRNA RT-qPCR 2018 Differential centrifugation|Polyethylene glycol-based precipitation|Centrifugation Exosomes 2279 29295981 Homo sapiens Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis Plasma ts Secondary-progressive multiple sclerosis miRNA RT-qPCR 2018 Differential centrifugation|Polyethylene glycol-based precipitation|Centrifugation Exosomes 2280 29295981 Homo sapiens Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis Plasma ts Multiple sclerosis in remission phase miRNA RT-qPCR 2018 Differential centrifugation|Polyethylene glycol-based precipitation|Centrifugation Exosomes 2281 29295981 Homo sapiens Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis Plasma ts Multiple sclerosis in relapse phase miRNA RT-qPCR 2018 Differential centrifugation|Polyethylene glycol-based precipitation|Centrifugation Exosomes 2282 29295981 Homo sapiens Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis Plasma ts Male with multiple sclerosis miRNA RT-qPCR 2018 Differential centrifugation|Polyethylene glycol-based precipitation|Centrifugation Exosomes 2283 29295981 Homo sapiens Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis Plasma ts Female with multiple sclerosis miRNA RT-qPCR 2018 Differential centrifugation|Polyethylene glycol-based precipitation|Centrifugation Exosomes 2284 30863515 Homo sapiens Proteomic analysis reveals procoagulant properties of cigarette smoke-induced extracellular vesicles Lung epithelial cells cl BEAS-2B Protein|Lipid Flow cytometry|Mass spectrometry 2019 Centrifugal ultrafiltration|Size exclusion chromatography Extracellular vesicles 2285 30863515 Homo sapiens Proteomic analysis reveals procoagulant properties of cigarette smoke-induced extracellular vesicles Lung epithelial cells cl BEAS-2B Protein|Lipid Flow cytometry|Mass spectrometry 2019 Centrifugal ultrafiltration|Size exclusion chromatography Extracellular vesicles 2286 30891164 Homo sapiens Extracellular vesicles derived from natural killer cells use multiple cytotoxic proteins and killing mechanisms to target cancer cells Natural killer cells ts PBMC-derived NK cells - activated Protein ELISA 2019 Polyethylene glycol-based precipitation|Centrifugation|Dialysis Extracellular vesicles 2287 30891164 Homo sapiens Extracellular vesicles derived from natural killer cells use multiple cytotoxic proteins and killing mechanisms to target cancer cells Natural killer cells ts PBMC-derived NK cells - inactivated Protein ELISA 2019 Polyethylene glycol-based precipitation|Centrifugation|Dialysis Extracellular vesicles 2288 30891164 Homo sapiens Extracellular vesicles derived from natural killer cells use multiple cytotoxic proteins and killing mechanisms to target cancer cells Natural killer cells cl NK92 Protein ELISA 2019 Polyethylene glycol-based precipitation|Centrifugation|Dialysis Extracellular vesicles 2289 30891164 Homo sapiens Extracellular vesicles derived from natural killer cells use multiple cytotoxic proteins and killing mechanisms to target cancer cells Neuroblastoma cells cl CHLA255 Protein ELISA 2019 Polyethylene glycol-based precipitation|Centrifugation|Dialysis Extracellular vesicles 2290 30891164 Homo sapiens Extracellular vesicles derived from natural killer cells use multiple cytotoxic proteins and killing mechanisms to target cancer cells Acute lymphoblastic leukemia cells cl SupB15 Protein ELISA 2019 Polyethylene glycol-based precipitation|Centrifugation|Dialysis Extracellular vesicles 2291 30891164 Homo sapiens Extracellular vesicles derived from natural killer cells use multiple cytotoxic proteins and killing mechanisms to target cancer cells Glioma cells cl D54MG Protein ELISA 2019 Polyethylene glycol-based precipitation|Centrifugation|Dialysis Extracellular vesicles 2292 30891164 Homo sapiens Extracellular vesicles derived from natural killer cells use multiple cytotoxic proteins and killing mechanisms to target cancer cells Breast cancer cells cl MCF7 Protein ELISA 2019 Polyethylene glycol-based precipitation|Centrifugation|Dialysis Extracellular vesicles 2293 30891164 Homo sapiens Extracellular vesicles derived from natural killer cells use multiple cytotoxic proteins and killing mechanisms to target cancer cells Prostate cancer cells cl DU145 Protein ELISA 2019 Polyethylene glycol-based precipitation|Centrifugation|Dialysis Extracellular vesicles 2294 30891164 Homo sapiens Extracellular vesicles derived from natural killer cells use multiple cytotoxic proteins and killing mechanisms to target cancer cells Cervical cancer cells cl HeLa Protein ELISA 2019 Polyethylene glycol-based precipitation|Centrifugation|Dialysis Extracellular vesicles 2295 30891164 Homo sapiens Extracellular vesicles derived from natural killer cells use multiple cytotoxic proteins and killing mechanisms to target cancer cells Liver cancer cells cl HepG2 Protein ELISA 2019 Polyethylene glycol-based precipitation|Centrifugation|Dialysis Extracellular vesicles 2296 29339034 Homo sapiens Extracellular matrix proteins and carcinoembryonic antigen-related cell adhesion molecules characterize pancreatic duct fluid exosomes in patients with pancreatic cancer Pancreatic duct fluid ts From patients with Pancreatic ductal adenocarcinoma Protein Mass spectrometry 2018 Differential centrifugation|Ultracentrifugation Exosomes 2297 29339034 Homo sapiens Extracellular matrix proteins and carcinoembryonic antigen-related cell adhesion molecules characterize pancreatic duct fluid exosomes in patients with pancreatic cancer Pancreatic duct fluid ts From patients with IPMN with microinvasive cancer (IPMNca) Protein Mass spectrometry 2018 Differential centrifugation|Ultracentrifugation Exosomes 2298 29339034 Homo sapiens Extracellular matrix proteins and carcinoembryonic antigen-related cell adhesion molecules characterize pancreatic duct fluid exosomes in patients with pancreatic cancer Pancreatic duct fluid ts From patients with intraductal papillary mucinous neoplasm patients (IPMN) Protein Mass spectrometry 2018 Differential centrifugation|Ultracentrifugation Exosomes 2299 29339034 Homo sapiens Extracellular matrix proteins and carcinoembryonic antigen-related cell adhesion molecules characterize pancreatic duct fluid exosomes in patients with pancreatic cancer Pancreatic duct fluid ts From patients with benign pancreatic disease Protein Mass spectrometry 2018 Differential centrifugation|Ultracentrifugation Exosomes 2300 31489147 Homo sapiens Inflammation potentiates miR-939 expression and packaging into small extracellular vesicles Monocytes cl THP-1 Protein|miRNA Immuno-EM|Western blotting|qRT-PCR 2019 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2301 31489147 Homo sapiens Inflammation potentiates miR-939 expression and packaging into small extracellular vesicles Blood ts PBMC from CRPS patients Protein Western blotting 2019 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2302 31489147 Homo sapiens Inflammation potentiates miR-939 expression and packaging into small extracellular vesicles Monocytes cl THP-1 miRNA qRT-PCR 2019 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2303 31489147 Homo sapiens Inflammation potentiates miR-939 expression and packaging into small extracellular vesicles Monocytes cl THP-1 miRNA qRT-PCR 2019 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2304 31489147 Homo sapiens Inflammation potentiates miR-939 expression and packaging into small extracellular vesicles Monocytes cl THP-1 miRNA qRT-PCR 2019 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2305 31489147 Homo sapiens Inflammation potentiates miR-939 expression and packaging into small extracellular vesicles Monocytes cl THP-1 miRNA qRT-PCR 2019 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2306 31489147 Homo sapiens Inflammation potentiates miR-939 expression and packaging into small extracellular vesicles Monocytes cl THP-1 miRNA qRT-PCR 2019 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2307 31489147 Homo sapiens Inflammation potentiates miR-939 expression and packaging into small extracellular vesicles Monocytes ts PBMC-derived monocytes - Healthy control miRNA qRT-PCR 2019 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2308 31489147 Homo sapiens Inflammation potentiates miR-939 expression and packaging into small extracellular vesicles Monocytes ts PBMC-derived monocytes - CRPS patients miRNA qRT-PCR 2019 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2309 31489147 Homo sapiens Inflammation potentiates miR-939 expression and packaging into small extracellular vesicles Natural killer cells ts PBMC-derived NK cells - Healthy control miRNA qRT-PCR 2019 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2310 31489147 Homo sapiens Inflammation potentiates miR-939 expression and packaging into small extracellular vesicles Natural killer cells ts PBMC-derived NK cells - CRPS patients miRNA qRT-PCR 2019 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2311 31489147 Homo sapiens Inflammation potentiates miR-939 expression and packaging into small extracellular vesicles B cells ts PBMC-derived B cells - Healthy control miRNA qRT-PCR 2019 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2312 31489147 Homo sapiens Inflammation potentiates miR-939 expression and packaging into small extracellular vesicles B cells ts PBMC-derived B-cells - CRPS patients miRNA qRT-PCR 2019 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2313 31489147 Homo sapiens Inflammation potentiates miR-939 expression and packaging into small extracellular vesicles T cells ts PBMC-derived CD4+ T cells - Healthy control miRNA qRT-PCR 2019 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2314 31489147 Homo sapiens Inflammation potentiates miR-939 expression and packaging into small extracellular vesicles T cells ts PBMC-derived CD4+ T cells - CRPS patients miRNA qRT-PCR 2019 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2315 31489147 Homo sapiens Inflammation potentiates miR-939 expression and packaging into small extracellular vesicles T cells ts PBMC-derived CD8+ T cells - Healthy control miRNA qRT-PCR 2019 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2316 31489147 Homo sapiens Inflammation potentiates miR-939 expression and packaging into small extracellular vesicles T cells ts PBMC-derived CD8+ T cells - CRPS patients miRNA qRT-PCR 2019 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2317 31762962 Homo sapiens Small RNA-sequence analysis of plasma-derived extracellular vesicle miRNAs in smokers and patients with chronic obstructive pulmonary disease as circulating biomarkers Plasma ts Non-smokers Protein|small RNA Western blotting|Small RNA sequencing 2019 ExoQuick Kit Extracellular vesicles/Exosomes 2318 31762962 Homo sapiens Small RNA-sequence analysis of plasma-derived extracellular vesicle miRNAs in smokers and patients with chronic obstructive pulmonary disease as circulating biomarkers Plasma ts Smokers Protein|small RNA Western blotting|Small RNA sequencing 2019 ExoQuick Kit Extracellular vesicles/Exosomes 2319 31762962 Homo sapiens Small RNA-sequence analysis of plasma-derived extracellular vesicle miRNAs in smokers and patients with chronic obstructive pulmonary disease as circulating biomarkers Plasma ts COPD patients Protein|small RNA Western blotting|Small RNA sequencing 2019 ExoQuick Kit Extracellular vesicles/Exosomes 2320 31762962 Homo sapiens Small RNA-sequence analysis of plasma-derived extracellular vesicle miRNAs in smokers and patients with chronic obstructive pulmonary disease as circulating biomarkers Lung epithelial cells cl BEAS-2B miRNA qRT-PCR 2019 Cell culture media exosome purification and RNA isolation Kit Exosomes 2321 31762962 Homo sapiens Small RNA-sequence analysis of plasma-derived extracellular vesicle miRNAs in smokers and patients with chronic obstructive pulmonary disease as circulating biomarkers Lung epithelial cells cl BEAS-2B miRNA qRT-PCR 2019 Cell culture media exosome purification and RNA isolation Kit Exosomes 2322 31762962 Homo sapiens Small RNA-sequence analysis of plasma-derived extracellular vesicle miRNAs in smokers and patients with chronic obstructive pulmonary disease as circulating biomarkers Monocytes cl U937 miRNA qRT-PCR 2019 Cell culture media exosome purification and RNA isolation Kit Exosomes 2323 31762962 Homo sapiens Small RNA-sequence analysis of plasma-derived extracellular vesicle miRNAs in smokers and patients with chronic obstructive pulmonary disease as circulating biomarkers Monocytes cl U937 miRNA qRT-PCR 2019 Cell culture media exosome purification and RNA isolation Kit Exosomes 2324 31807237 Homo sapiens Tetraspanin CD82 interaction with cholesterol promotes extracellular vesicle-mediated release of ezrin to inhibit tumour cell movement Prostate cancer cells cl Dul145 Protein Western blotting 2019 Differential centrifugation|Ultracentrifugation Exosomes 2325 31807237 Homo sapiens Tetraspanin CD82 interaction with cholesterol promotes extracellular vesicle-mediated release of ezrin to inhibit tumour cell movement Prostate cancer cells cl Dul145 Protein Western blotting 2019 Differential centrifugation|Ultracentrifugation Exosomes 2326 31807237 Homo sapiens Tetraspanin CD82 interaction with cholesterol promotes extracellular vesicle-mediated release of ezrin to inhibit tumour cell movement Prostate cancer cells cl Dul145 Protein Western blotting 2019 Differential centrifugation|Ultracentrifugation Exosomes 2327 31807237 Homo sapiens Tetraspanin CD82 interaction with cholesterol promotes extracellular vesicle-mediated release of ezrin to inhibit tumour cell movement Prostate cancer cells cl LnCap Protein Western blotting 2019 Differential centrifugation|Ultracentrifugation Exosomes 2328 31807237 Homo sapiens Tetraspanin CD82 interaction with cholesterol promotes extracellular vesicle-mediated release of ezrin to inhibit tumour cell movement Prostate cancer cells cl LnCap Protein Western blotting 2019 Differential centrifugation|Ultracentrifugation Exosomes 2329 32487994 Homo sapiens Plasma-derived extracellular vesicles from Plasmodium vivax patients signal spleen fibroblasts via NF-kB facilitating parasite cytoadherence Plasma ts Healthy donors Protein Western blotting|Mass spectrometry|Flow cytometry 2020 Centrifugation|Size exclusion chromatography Extracellular vesicles 2330 32487994 Homo sapiens Plasma-derived extracellular vesicles from Plasmodium vivax patients signal spleen fibroblasts via NF-kB facilitating parasite cytoadherence Plasma ts Plasmodium vivax (Malaria) patients Protein Western blotting|Mass spectrometry|Flow cytometry 2020 Centrifugation|Size exclusion chromatography Extracellular vesicles 2331 36635419 Homo sapiens Intradermally delivered mRNA-encapsulating extracellular vesicles for collagen-replacement therapy Fibroblasts cl Normal human dermal fibroblasts Protein|mRNA RT-qPCR|Western blotting 2023 Centrifugal ultrafiltration|Immunoaffinity capture Extracellular vesicles 2332 36640325 Mus musculus Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis Adipocytes ts Visceral (gonadal) adipose tissue Protein|miRNA Western blotting|Small RNA sequencing|RT-qPCR 2023 Differential centrifugation|Ultracentrifugation Exosomes 2333 36640325 Mus musculus Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis Adipocytes ts Visceral (gonadal) adipose tissue Protein|miRNA Western blotting|Small RNA sequencing|RT-qPCR 2023 Differential centrifugation|Ultracentrifugation Exosomes 2334 36640325 Mus musculus Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis Adipocytes ts Visceral (gonadal) adipose tissue miRNA RT-qPCR 2023 Differential centrifugation|Ultracentrifugation Exosomes 2335 36640325 Mus musculus Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis Adipocytes ts Visceral (gonadal) adipose tissue miRNA RT-qPCR 2023 Differential centrifugation|Ultracentrifugation Exosomes 2336 36640325 Mus musculus Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis Adipocytes ts Visceral (gonadal) adipose tissue miRNA RT-qPCR 2023 Differential centrifugation|Ultracentrifugation Exosomes 2337 36640325 Mus musculus Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis Plasma ts Lean mice miRNA Small RNA sequencing 2023 ExoQuick Kit|Centrifugation Exosomes 2338 36640325 Mus musculus Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis Plasma ts Obese mice miRNA Small RNA sequencing 2023 ExoQuick Kit|Centrifugation Exosomes 2339 36640325 Mus musculus Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis Adipocytes ts Inguinal adipose tissue miRNA Small RNA sequencing|RT-qPCR 2023 Differential centrifugation|Ultracentrifugation Exosomes 2340 36640325 Mus musculus Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis Adipocytes ts Inguinal adipose tissue miRNA Small RNA sequencing 2023 Differential centrifugation|Ultracentrifugation Exosomes 2341 36640325 Mus musculus Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis Adipocytes ts Brown adipose tissue miRNA Small RNA sequencing|RT-qPCR 2023 Differential centrifugation|Ultracentrifugation Exosomes 2342 36640325 Mus musculus Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis Adipocytes ts Brown adipose tissue miRNA Small RNA sequencing 2023 Differential centrifugation|Ultracentrifugation Exosomes 2343 36640325 Mus musculus Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis Adipocytes ts Inguinal adipose tissue miRNA RT-qPCR 2023 Differential centrifugation|Ultracentrifugation Exosomes 2344 36640325 Mus musculus Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis Adipocytes ts Brown adipose tissue miRNA RT-qPCR 2023 Differential centrifugation|Ultracentrifugation Exosomes 2345 36640325 Mus musculus Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis Adipocytes ts Inguinal adipose tissue miRNA RT-qPCR 2023 Differential centrifugation|Ultracentrifugation Exosomes 2346 36640325 Mus musculus Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis Adipocytes ts Brown adipose tissue miRNA RT-qPCR 2023 Differential centrifugation|Ultracentrifugation Exosomes 2347 36640325 Mus musculus Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis Adipocytes ts Visceral (Gonadal) adipose tissue miRNA RT-qPCR 2023 Differential centrifugation|Ultracentrifugation Exosomes 2348 36640325 Mus musculus Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis Adipocytes ts Visceral (Gonadal) adipose tissue miRNA RT-qPCR 2023 Differential centrifugation|Ultracentrifugation Exosomes 2349 36640325 Mus musculus Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis Adipocytes ts Mature adipocytes derived from visceral (gonadal) adipose tissue miRNA RT-qPCR 2023 Differential centrifugation|Ultracentrifugation Exosomes 2350 36640325 Mus musculus Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis Stromal vascular fraction ts Stromal vascular fraction derived from visceral (gonadal) adipose tissue miRNA RT-qPCR 2023 Differential centrifugation|Ultracentrifugation Exosomes 2351 36640325 Mus musculus Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis Adipocytes ts Mature adipocytes derived from visceral (gonadal) adipose tissue miRNA RT-qPCR 2023 Differential centrifugation|Ultracentrifugation Exosomes 2352 36640325 Mus musculus Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis Stromal vascular fraction ts Stromal vascular fraction derived from visceral (gonadal) adipose tissue miRNA RT-qPCR 2023 Differential centrifugation|Ultracentrifugation Exosomes 2353 36640325 Mus musculus Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis Adipocytes ts Mature adipocytes derived from visceral (gonadal) adipose tissue miRNA RT-qPCR 2023 Differential centrifugation|Ultracentrifugation Exosomes 2354 36640325 Mus musculus Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis Stromal vascular fraction ts Stromal vascular fraction derived from visceral (gonadal) adipose tissue miRNA RT-qPCR 2023 Differential centrifugation|Ultracentrifugation Exosomes 2355 36708245 Homo sapiens Faeces-derived extracellular vesicles participate in the onset of barrier dysfunction leading to liver diseases Faeces ts Control - non-NAFLD/non-NASH donor Protein|Lipid Pierce Chromogenic Endotoxin Quant Kit|Western blotting 2023 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2356 36708245 Homo sapiens Faeces-derived extracellular vesicles participate in the onset of barrier dysfunction leading to liver diseases Faeces ts NAFLD patients Protein|Lipid Pierce Chromogenic Endotoxin Quant Kit|Western blotting 2023 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2357 36708245 Homo sapiens Faeces-derived extracellular vesicles participate in the onset of barrier dysfunction leading to liver diseases Faeces ts NASH patients Protein|Lipid Pierce Chromogenic Endotoxin Quant Kit|Western blotting 2023 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2358 36708245 Homo sapiens Faeces-derived extracellular vesicles participate in the onset of barrier dysfunction leading to liver diseases Blood ts Control - non-NAFLD/non-NASH donor Protein|Lipid Pierce Chromogenic Endotoxin Quant Kit|Western blotting 2023 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2359 36708245 Homo sapiens Faeces-derived extracellular vesicles participate in the onset of barrier dysfunction leading to liver diseases Blood ts NAFLD patients Protein|Lipid Pierce Chromogenic Endotoxin Quant Kit|Western blotting 2023 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2360 36708245 Homo sapiens Faeces-derived extracellular vesicles participate in the onset of barrier dysfunction leading to liver diseases Blood ts NASH patients Protein|Lipid Pierce Chromogenic Endotoxin Quant Kit|Western blotting 2023 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2361 36717543 Rattus norvegicus Schwann cell-derived exosomes containing MFG-E8 modify macrophage/microglial polarization for attenuating inflammation via the SOCS3/STAT3 pathway after spinal cord injury Schwann cells ts Sciatic nerve-derived schwann cells Protein Western blotting|Mass spectrometry 2023 Differential centrifugation|Ultracentrifugation Exosomes 2362 36748335 Homo sapiens Hypoxia promotes EV secretion by impairing lysosomal homeostasis in HNSCC through negative regulation of ATP6V1A by HIF-1α Oral cancer cells cl HN6 Protein Western blotting 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 2363 36748335 Homo sapiens Hypoxia promotes EV secretion by impairing lysosomal homeostasis in HNSCC through negative regulation of ATP6V1A by HIF-1α Oral cancer cells cl HN6 Protein Western blotting 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 2364 36748335 Homo sapiens Hypoxia promotes EV secretion by impairing lysosomal homeostasis in HNSCC through negative regulation of ATP6V1A by HIF-1α Oral cancer cells cl CAL27 Protein Western blotting 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 2365 36748335 Homo sapiens Hypoxia promotes EV secretion by impairing lysosomal homeostasis in HNSCC through negative regulation of ATP6V1A by HIF-1α Oral cancer cells cl CAL27 Protein Western blotting 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 2366 36759608 Mus musculus Adipocyte-derived extracellular vesicles increase insulin secretion through transport of insulinotropic protein cargo Adipocytes ts C57BL/6 J eWAT-derived adipocytes - Lean Protein|miRNA Mass spectrometry|RT-PCR 2023 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2367 36759608 Mus musculus Adipocyte-derived extracellular vesicles increase insulin secretion through transport of insulinotropic protein cargo Adipocytes ts C57BL/6 J eWAT-derived adipocytes - Lean Protein Mass spectrometry|Western blotting 2023 Centrifugal ultrafiltration|Size exclusion chromatography Extracellular vesicles 2368 36759608 Mus musculus Adipocyte-derived extracellular vesicles increase insulin secretion through transport of insulinotropic protein cargo Adipocytes ts C57BL/6 J eWAT-derived adipocytes - Diet-induced obesity Protein|miRNA Mass spectrometry|RT-PCR 2023 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2369 36759608 Mus musculus Adipocyte-derived extracellular vesicles increase insulin secretion through transport of insulinotropic protein cargo Adipocytes ts C57BL/6 J eWAT-derived adipocytes - Diet-induced obesity Protein Mass spectrometry|Western blotting 2023 Centrifugal ultrafiltration|Size exclusion chromatography Extracellular vesicles 2370 36759608 Homo sapiens Adipocyte-derived extracellular vesicles increase insulin secretion through transport of insulinotropic protein cargo Adipocytes ts Liposuction patient-derived adipocytes Protein Mass spectrometry 2023 Differential centrifugation|Ultracentrifugation|Size exclusion chromatography Extracellular vesicles 2371 36759608 Homo sapiens Adipocyte-derived extracellular vesicles increase insulin secretion through transport of insulinotropic protein cargo Stromal vascular fraction ts Liposuction patient-derived SVF Protein Mass spectrometry 2023 Differential centrifugation|Ultracentrifugation|Size exclusion chromatography Extracellular vesicles 2372 35087866 Rattus norvegicus Exercise-Induced Extracellular Vesicles Delay the Progression of Prostate Cancer Plasma ts Plasma - Sedentary RNA RNA sequencing 2022 Size exclusion chromatography|Filtration Extracellular vesicles 2373 35087866 Rattus norvegicus Exercise-Induced Extracellular Vesicles Delay the Progression of Prostate Cancer Plasma ts Plasma - Pre-run RNA RNA sequencing 2022 Size exclusion chromatography|Filtration Extracellular vesicles 2374 35087866 Rattus norvegicus Exercise-Induced Extracellular Vesicles Delay the Progression of Prostate Cancer Plasma ts Plasma - Post-run RNA RNA sequencing 2022 Size exclusion chromatography|Filtration Extracellular vesicles 2375 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma ts Plasma Protein Mass spectrometry 2021 exoEasy Maxi Kit Extracellular vesicles 2376 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma ts Plasma Protein Mass spectrometry 2021 Size exclusion chromatography Extracellular vesicles 2377 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma ts Plasma Protein Mass spectrometry 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2378 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma ts SEC Fraction 14 Protein Mass spectrometry 2021 Size exclusion chromatography Extracellular vesicles 2379 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma ts SEC Fraction 15 Protein Mass spectrometry 2021 Size exclusion chromatography Extracellular vesicles 2380 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma ts SEC Fraction 16 Protein Mass spectrometry 2021 Size exclusion chromatography Extracellular vesicles 2381 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma ts SEC Fraction 17 Protein Mass spectrometry 2021 Size exclusion chromatography Extracellular vesicles 2382 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma ts SEC Fraction 18 Protein Mass spectrometry 2021 Size exclusion chromatography Extracellular vesicles 2383 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma ts SEC Fraction 19 Protein Mass spectrometry 2021 Size exclusion chromatography Extracellular vesicles 2384 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma ts SEC Fraction 20 Protein Mass spectrometry 2021 Size exclusion chromatography Extracellular vesicles 2385 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma ts SEC Fraction 21 Protein Mass spectrometry 2021 Size exclusion chromatography Extracellular vesicles 2386 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma ts SEC Column 1 Fraction 14-15 Protein Mass spectrometry 2021 Size exclusion chromatography Extracellular vesicles 2387 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma ts SEC Fraction Column 1 16-17 Protein Mass spectrometry 2021 Size exclusion chromatography Extracellular vesicles 2388 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma ts SEC Fraction Column 1 18-19 Protein Mass spectrometry 2021 Size exclusion chromatography Extracellular vesicles 2389 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma ts SEC Column 1 Fraction 20-21 Protein Mass spectrometry 2021 Size exclusion chromatography Extracellular vesicles 2390 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma ts SEC Column 2 Fraction 14-15 Protein Mass spectrometry 2021 Size exclusion chromatography Extracellular vesicles 2391 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma ts SEC Fraction Column 2 16-17 Protein Mass spectrometry 2021 Size exclusion chromatography Extracellular vesicles 2392 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma ts SEC Fraction Column 2 18-19 Protein Mass spectrometry 2021 Size exclusion chromatography Extracellular vesicles 2393 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma ts SEC Column 2 Fraction 20-21 Protein Mass spectrometry 2021 Size exclusion chromatography Extracellular vesicles 2394 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma ts SEC Column 3 Fraction 14-15 Protein Mass spectrometry 2021 Size exclusion chromatography Extracellular vesicles 2395 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma ts SEC Fraction Column 3 16-17 Protein Mass spectrometry 2021 Size exclusion chromatography Extracellular vesicles 2396 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma ts SEC Fraction Column 3 18-19 Protein Mass spectrometry 2021 Size exclusion chromatography Extracellular vesicles 2397 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma ts SEC Column 3 Fraction 20-21 Protein Mass spectrometry 2021 Size exclusion chromatography Extracellular vesicles 2398 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma ts SEC Fraction 14-21 Protein Mass spectrometry 2021 Size exclusion chromatography Extracellular vesicles 2399 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma ts Plasma Protein Mass spectrometry 2021 Size exclusion chromatography Extracellular vesicles 2400 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma ts Plasma Protein Mass spectrometry 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2401 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma ts Platelet-rich plasma Protein Mass spectrometry 2021 Size exclusion chromatography Extracellular vesicles 2402 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma ts Platelet-rich plasma Protein Mass spectrometry 2021 Size exclusion chromatography Extracellular vesicles 2403 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma ts Platelet-rich plasma Protein Mass spectrometry 2021 Size exclusion chromatography Extracellular vesicles 2404 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma ts Platelet-rich plasma Protein Mass spectrometry 2021 Size exclusion chromatography Extracellular vesicles 2405 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma ts Platelet-rich plasma Protein Mass spectrometry 2021 Size exclusion chromatography Extracellular vesicles 2406 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma ts Platelet-rich plasma Protein Mass spectrometry 2021 Size exclusion chromatography Extracellular vesicles 2407 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Myoblasts cl Human skeletal myoblasts (HSMM) or Myotubes Protein Mass spectrometry 2021 Filtration|Size exclusion chromatography Extracellular vesicles 2408 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Adipocytes cl Differentiated adipocytes Protein Mass spectrometry 2021 Filtration|Size exclusion chromatography Extracellular vesicles 2409 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Platelets ts Platelets Protein Mass spectrometry 2021 Filtration|Size exclusion chromatography Extracellular vesicles 2410 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Hepatocytes cl Huh7 Protein Mass spectrometry 2021 Filtration|Size exclusion chromatography Extracellular vesicles 2411 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Leukocytes ts Leukocytes from blood Protein Mass spectrometry 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2412 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma ts Plasma Protein Mass spectrometry 2021 Size exclusion chromatography Extracellular vesicles 2413 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma ts Plasma Protein Mass spectrometry 2021 Size exclusion chromatography Extracellular vesicles 2414 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma ts Plasma Protein Mass spectrometry 2021 Size exclusion chromatography Extracellular vesicles 2415 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma ts Plasma Protein Mass spectrometry 2021 Size exclusion chromatography Extracellular vesicles 2416 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma ts SEC Column 1 Fraction 14-21 Protein Mass spectrometry 2021 Size exclusion chromatography Extracellular vesicles 2417 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma ts SEC Column 2 Fraction 14-21 Protein Mass spectrometry 2021 Size exclusion chromatography Extracellular vesicles 2418 34355211 Homo sapiens A size-exclusion-based approach for purifying extracellular vesicles from human plasma Plasma ts SEC Column 3 Fraction 14-21 Protein Mass spectrometry 2021 Size exclusion chromatography Extracellular vesicles 2419 35939247 Homo sapiens Metastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems Breast cancer cells cl MDA-MB-231T Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Exosomes 2420 35939247 Homo sapiens Metastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems Breast cancer cells cl MDA-MB-231T Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Exosomes 2421 35939247 Homo sapiens Metastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems Breast cancer cells cl MDA-MB-435 Protein Western blotting|Mass spectrometry 2022 Differential centrifugation|Ultracentrifugation Exosomes 2422 35939247 Homo sapiens Metastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems Breast cancer cells cl MDA-MB-435 Protein Western blotting|Mass spectrometry 2022 Differential centrifugation|Ultracentrifugation Exosomes 2423 35939247 Homo sapiens Metastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems Breast cancer cells cl T47D Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Exosomes 2424 35939247 Homo sapiens Metastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems Breast cancer cells cl MCF-7 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Exosomes 2425 35939247 Homo sapiens Metastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems Breast cancer cells cl MDA-MB-453 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Exosomes 2426 35939247 Homo sapiens Metastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems Breast cancer cells cl MDA-MB-436 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Exosomes 2427 35939247 Homo sapiens Metastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems Breast cancer cells cl MDA-MB-468 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Exosomes 2428 35939247 Homo sapiens Metastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems Breast cancer cells cl BT-474 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Exosomes 2429 35939247 Homo sapiens Metastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems Breast cancer cells cl BT549 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Exosomes 2430 35939247 Homo sapiens Metastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems Breast cancer cells cl JIMT1-BR Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Exosomes 2431 29320704 Homo sapiens Extracellular Vesicles Provide a Means for Tissue Crosstalk during Exercise Plasma ts Plasma - 20K pellet Protein Mass spectrometry 2018 Centrifugation Extracellular vesicles 2432 29320704 Homo sapiens Extracellular Vesicles Provide a Means for Tissue Crosstalk during Exercise Plasma ts Plasma - 100K pellet Protein Mass spectrometry 2018 Ultracentrifugation Extracellular vesicles 2433 29320704 Homo sapiens Extracellular Vesicles Provide a Means for Tissue Crosstalk during Exercise Plasma ts Plasma Protein Mass spectrometry 2018 Centrifugation Extracellular vesicles 2434 29320704 Homo sapiens Extracellular Vesicles Provide a Means for Tissue Crosstalk during Exercise Plasma ts Plasma Protein Mass spectrometry 2018 Centrifugation Extracellular vesicles 2435 29320704 Homo sapiens Extracellular Vesicles Provide a Means for Tissue Crosstalk during Exercise Plasma ts Plasma Protein Mass spectrometry 2018 Centrifugation Extracellular vesicles 2436 29320704 Homo sapiens Extracellular Vesicles Provide a Means for Tissue Crosstalk during Exercise Plasma ts Plasma Protein Mass spectrometry 2018 Centrifugation Extracellular vesicles 2437 29335551 Homo sapiens Tumor-derived exosomal miR-1247-3p induces cancer-associated fibroblast activation to foster lung metastasis of liver cancer Liver cancer cells cl CSQT-2 Protein|miRNA Western blotting|Microarray|qRT-PCR 2018 Filtration|Differential centrifugation|Ultracentrifugation Exosomes 2438 29335551 Homo sapiens Tumor-derived exosomal miR-1247-3p induces cancer-associated fibroblast activation to foster lung metastasis of liver cancer Liver cancer cells cl HCC-LM3 Protein|miRNA Western blotting|Microarray|qRT-PCR 2018 Filtration|Differential centrifugation|Ultracentrifugation Exosomes 2439 29335551 Homo sapiens Tumor-derived exosomal miR-1247-3p induces cancer-associated fibroblast activation to foster lung metastasis of liver cancer Liver cancer cells cl HepG2 Protein|miRNA Western blotting|Microarray|qRT-PCR 2018 Filtration|Differential centrifugation|Ultracentrifugation Exosomes 2440 29335551 Homo sapiens Tumor-derived exosomal miR-1247-3p induces cancer-associated fibroblast activation to foster lung metastasis of liver cancer Liver cancer cells cl MHCC-97L Protein|miRNA Western blotting|Microarray|qRT-PCR 2018 Filtration|Differential centrifugation|Ultracentrifugation Exosomes 2441 36591510 Homo sapiens Detection of circulating KRAS mutant DNA in extracellular vesicles using droplet digital PCR in patients with colon cancer Plasma ts Colon cancer patients with KRAS mutation Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2442 34489604 Mus musculus Hepatocyte-derived exosomes from early onset obese mice promote insulin sensitivity through miR-3075 Hepatocytes ts Primary hepatocytes - C57BL/6 Protein|miRNA Western blotting|Small RNA sequencing 2021 Centrifugation|Filtration|Ultracentrifugation Exosomes 2443 34489604 Mus musculus Hepatocyte-derived exosomes from early onset obese mice promote insulin sensitivity through miR-3075 Hepatocytes ts Primary hepatocytes - C57BL/6 Protein|miRNA Western blotting|Small RNA sequencing 2021 Centrifugation|Filtration|Ultracentrifugation Exosomes 2444 34489604 Mus musculus Hepatocyte-derived exosomes from early onset obese mice promote insulin sensitivity through miR-3075 Hepatocytes ts Primary hepatocytes - C57BL/6 Protein|miRNA Western blotting|Small RNA sequencing 2021 Centrifugation|Filtration|Ultracentrifugation Exosomes 2445 34489604 Mus musculus Hepatocyte-derived exosomes from early onset obese mice promote insulin sensitivity through miR-3075 Hepatocytes ts Primary hepatocytes - hepatocyte-specific Cas9 transgenic C57BL/6 Protein|miRNA Western blotting|qRT-PCR 2021 Centrifugation|Filtration|Ultracentrifugation Exosomes 2446 34489604 Mus musculus Hepatocyte-derived exosomes from early onset obese mice promote insulin sensitivity through miR-3075 Hepatocytes ts Primary hepatocytes - hepatocyte-specific Cas9 transgenic C57BL/6 Protein|miRNA Western blotting|qRT-PCR 2021 Centrifugation|Filtration|Ultracentrifugation Exosomes 2447 34489604 Mus musculus Hepatocyte-derived exosomes from early onset obese mice promote insulin sensitivity through miR-3075 Hepatocytes ts Primary hepatocytes - hepatocyte-specific Cas9 transgenic C57BL/6 miRNA qRT-PCR 2021 Centrifugation|Filtration|Ultracentrifugation Exosomes 2448 34465793 Homo sapiens Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer Breast cancer cells cl MCF7 - 100K pellet miRNA miRNA array|qPCR 2021 Centrifugation|Ultracentrifugation Extracellular vesicles 2449 34465793 Homo sapiens Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer Breast cancer cells cl MCF7BoM2 - 100K pellet Protein|miRNA Western blotting|Immuno-EM|miRNA array|qPCR 2021 Centrifugation|Ultracentrifugation Extracellular vesicles 2450 34465793 Homo sapiens Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer Breast cancer cells cl MCF7 - 2K pellet miRNA qPCR 2021 Centrifugation Apoptotic bodies 2451 34465793 Homo sapiens Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer Breast cancer cells cl MCF7 - 10K pellet miRNA qPCR 2021 Centrifugation|Ultracentrifugation Microvesicles 2452 34465793 Homo sapiens Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer Breast cancer cells cl MCF7BoM2 - 2K pellet Protein|miRNA Western blotting|qPCR 2021 Centrifugation Apoptotic bodies 2453 34465793 Homo sapiens Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer Breast cancer cells cl MCF7BoM2 - 10K pellet Protein|miRNA Western blotting|qPCR 2021 Centrifugation|Ultracentrifugation Microvesicles 2454 34465793 Homo sapiens Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer Breast cancer cells cl T47D - 2K pellet miRNA qPCR 2021 Centrifugation Apoptotic bodies 2455 34465793 Homo sapiens Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer Breast cancer cells cl T47D - 10K pellet miRNA qPCR 2021 Centrifugation|Ultracentrifugation Microvesicles 2456 34465793 Homo sapiens Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer Breast cancer cells cl T47D - 100K pellet miRNA qPCR 2021 Centrifugation|Filtration|Ultracentrifugation Exosomes 2457 34465793 Homo sapiens Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer Breast cancer cells cl T47DBoM - 2K pellet miRNA qPCR 2021 Centrifugation Apoptotic bodies 2458 34465793 Homo sapiens Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer Breast cancer cells cl T47DBoM - 10K pellet miRNA qPCR 2021 Centrifugation|Ultracentrifugation Microvesicles 2459 34465793 Homo sapiens Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer Breast cancer cells cl T47DBoM - 100K pellet miRNA qPCR 2021 Centrifugation|Filtration|Ultracentrifugation Exosomes 2460 34465793 Homo sapiens Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer Serum ts Serum - ER-positive breast cancer patients miRNA qPCR 2021 Centrifugation|Filtration|Ultracentrifugation Exosomes 2461 34465793 Homo sapiens Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer Serum ts Serum - Her2-positive breast cancer patients miRNA qPCR 2021 Centrifugation|Filtration|Ultracentrifugation Exosomes 2462 34465793 Homo sapiens Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer Serum ts Serum - recurrence-free (10 year) TNBC patients miRNA qPCR 2021 Centrifugation|Filtration|Ultracentrifugation Exosomes 2463 34465793 Homo sapiens Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer Serum ts Serum - ER-negative breast cancer patients with visceral metastasis miRNA qPCR 2021 Centrifugation|Filtration|Ultracentrifugation Exosomes 2464 34465793 Homo sapiens Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer Serum ts Serum - ER-negative breast cancer patients with bone metastasis miRNA qPCR 2021 Centrifugation|Filtration|Ultracentrifugation Exosomes 2465 34465793 Homo sapiens Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer Serum ts Serum - ER-positive breast cancer patients with visceral metastasis miRNA qPCR 2021 Centrifugation|Filtration|Ultracentrifugation Exosomes 2466 34465793 Homo sapiens Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer Serum ts Serum - ER-positive breast cancer patients with bone metastasis miRNA qPCR 2021 Centrifugation|Filtration|Ultracentrifugation Exosomes 2467 34465793 Homo sapiens Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer Breast cancer cells cl MDA-MB-231 - 100K pellet miRNA qPCR 2021 Centrifugation|Filtration|Ultracentrifugation Exosomes 2468 34465793 Homo sapiens Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer Breast cancer cells cl MDA-MB-231BoM-1833 - 100K pellet miRNA qPCR 2021 Centrifugation|Filtration|Ultracentrifugation Exosomes 2469 34465793 Homo sapiens Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer Breast cancer cells ts Serum - nude mice bearing MCF7BoM2 miRNA qPCR 2021 Centrifugation|Filtration|Ultracentrifugation Exosomes 2470 34465793 Homo sapiens Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer Breast cancer cells ts Serum - nude mice bearing MCF7BoM2 miRNA qPCR 2021 Centrifugation|Filtration|Ultracentrifugation Exosomes 2471 34465793 Homo sapiens Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer Breast cancer cells cl|ts Primary tumour culture - nude mice bearing T47D miRNA qPCR 2021 Centrifugation|Filtration|Ultracentrifugation Exosomes 2472 34465793 Homo sapiens Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer Breast cancer cells cl|ts Liver metastatic lesion culture - nude mice bearing T47D miRNA qPCR 2021 Centrifugation|Filtration|Ultracentrifugation Exosomes 2473 34465793 Homo sapiens Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer Breast cancer cells cl|ts Kidney metastatic lesion culture - nude mice bearing T47D miRNA qPCR 2021 Centrifugation|Filtration|Ultracentrifugation Exosomes 2474 34465793 Homo sapiens Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer Breast cancer cells cl|ts Lung metastatic lesion culture - nude mice bearing T47D miRNA qPCR 2021 Centrifugation|Filtration|Ultracentrifugation Exosomes 2475 34465793 Homo sapiens Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer Breast cancer cells cl|ts Bone metastatic lesion culture - nude mice bearing T47D miRNA qPCR 2021 Centrifugation|Filtration|Ultracentrifugation Exosomes 2476 34401050 Homo sapiens TPI1-reduced extracellular vesicles mediated by Rab20 downregulation promotes aerobic glycolysis to drive hepatocarcinogenesis Liver cancer cells cl MHCC97L Protein Western blotting|Immuno-EM|Mass spectrometry 2021 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 2477 34401050 Homo sapiens TPI1-reduced extracellular vesicles mediated by Rab20 downregulation promotes aerobic glycolysis to drive hepatocarcinogenesis Liver cancer cells cl MHCC97L Protein Western blotting|Immuno-EM|Mass spectrometry 2021 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 2478 34401050 Homo sapiens TPI1-reduced extracellular vesicles mediated by Rab20 downregulation promotes aerobic glycolysis to drive hepatocarcinogenesis Hepatocytes cl MIHA Protein Western blotting|Immuno-EM 2021 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 2479 34401050 Homo sapiens TPI1-reduced extracellular vesicles mediated by Rab20 downregulation promotes aerobic glycolysis to drive hepatocarcinogenesis Hepatocytes cl MIHA Protein Western blotting|Immuno-EM 2021 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 2480 34401050 Homo sapiens TPI1-reduced extracellular vesicles mediated by Rab20 downregulation promotes aerobic glycolysis to drive hepatocarcinogenesis Hepatocytes cl MIHA Protein Western blotting|Immuno-EM 2021 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 2481 34401050 Homo sapiens TPI1-reduced extracellular vesicles mediated by Rab20 downregulation promotes aerobic glycolysis to drive hepatocarcinogenesis Liver cancer cells cl PLC/PRF/5 Protein Western blotting|Immuno-EM 2021 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 2482 34401050 Homo sapiens TPI1-reduced extracellular vesicles mediated by Rab20 downregulation promotes aerobic glycolysis to drive hepatocarcinogenesis Liver cancer cells cl PLC/PRF/5 - clone 1 Protein Western blotting|Immuno-EM 2021 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 2483 34401050 Homo sapiens TPI1-reduced extracellular vesicles mediated by Rab20 downregulation promotes aerobic glycolysis to drive hepatocarcinogenesis Liver cancer cells cl PLC/PRF/5 - clone 2 Protein Western blotting|Immuno-EM 2021 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 2484 34401050 Homo sapiens TPI1-reduced extracellular vesicles mediated by Rab20 downregulation promotes aerobic glycolysis to drive hepatocarcinogenesis Liver cancer cells cl MHCC97L Protein Western blotting|Immuno-EM 2021 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 2485 34401050 Homo sapiens TPI1-reduced extracellular vesicles mediated by Rab20 downregulation promotes aerobic glycolysis to drive hepatocarcinogenesis Liver cancer cells cl MHCC97L Protein Western blotting|Immuno-EM 2021 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 2486 34388111 Homo sapiens miRNA-221-3p derived from M2-polarized tumor-associated macrophage exosomes aggravates the growth and metastasis of osteosarcoma through SOCS3/JAK2/STAT3 axis Monocytic leukemia cells cl THP1 Protein|miRNA Western blotting|qRT-PCR 2021 Differential centrifugation|Ultracentrifugation Exosomes 2487 34388111 Homo sapiens miRNA-221-3p derived from M2-polarized tumor-associated macrophage exosomes aggravates the growth and metastasis of osteosarcoma through SOCS3/JAK2/STAT3 axis Monocytic leukemia cells cl THP1 Protein|miRNA Western blotting|qRT-PCR 2021 Differential centrifugation|Ultracentrifugation Exosomes 2488 34388111 Homo sapiens miRNA-221-3p derived from M2-polarized tumor-associated macrophage exosomes aggravates the growth and metastasis of osteosarcoma through SOCS3/JAK2/STAT3 axis Monocytic leukemia cells cl THP1 Protein|miRNA Western blotting|qRT-PCR 2021 Differential centrifugation|Ultracentrifugation Exosomes 2489 34388111 Homo sapiens miRNA-221-3p derived from M2-polarized tumor-associated macrophage exosomes aggravates the growth and metastasis of osteosarcoma through SOCS3/JAK2/STAT3 axis Monocytic leukemia cells cl THP1 Protein|miRNA Western blotting|qRT-PCR 2021 Differential centrifugation|Ultracentrifugation Exosomes 2490 34388111 Homo sapiens miRNA-221-3p derived from M2-polarized tumor-associated macrophage exosomes aggravates the growth and metastasis of osteosarcoma through SOCS3/JAK2/STAT3 axis Monocytic leukemia cells cl THP1 Protein|miRNA Western blotting|qRT-PCR 2021 Differential centrifugation|Ultracentrifugation Exosomes 2491 34370714 Homo sapiens MiR-195-5p and miR-205-5p in extracellular vesicles isolated from diabetic foot ulcer wound fluid decrease angiogenesis by inhibiting VEGFA expression Wound fluid ts Drainage fluid - post-operative (thyroidectomy) non-diabetic patients Protein|miRNA Western blotting|Microarray|qRT-PCR 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2492 34370714 Homo sapiens MiR-195-5p and miR-205-5p in extracellular vesicles isolated from diabetic foot ulcer wound fluid decrease angiogenesis by inhibiting VEGFA expression Wound fluid ts Wound fluid - ulcer sites of diabetic foot patients Protein|miRNA Western blotting|Microarray|qRT-PCR 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2493 34370714 Homo sapiens MiR-195-5p and miR-205-5p in extracellular vesicles isolated from diabetic foot ulcer wound fluid decrease angiogenesis by inhibiting VEGFA expression Serum ts Serum - non-diabetic patients miRNA qRT-PCR 2021 Polyethylene glycol-based precipitation|Centrifugation Extracellular vesicles 2494 34370714 Homo sapiens MiR-195-5p and miR-205-5p in extracellular vesicles isolated from diabetic foot ulcer wound fluid decrease angiogenesis by inhibiting VEGFA expression Serum ts Serum - diabetes mellitus patients with diabetic foot ulcers mRNA qRT-PCR 2021 Polyethylene glycol-based precipitation|Centrifugation Extracellular vesicles 2495 34370714 Homo sapiens MiR-195-5p and miR-205-5p in extracellular vesicles isolated from diabetic foot ulcer wound fluid decrease angiogenesis by inhibiting VEGFA expression Serum ts Serum - diabetes mellitus patients without diabetic foot ulcers mRNA qRT-PCR 2021 Polyethylene glycol-based precipitation|Centrifugation Extracellular vesicles 2496 34368811 Homo sapiens Isolation and characterization of extracellular vesicles in saliva of children with asthma Saliva ts Cell-free saliva - children (4 -14 year old) with asthma Protein Western blotting|ExoView immunocapture 2021 ExoQuick Kit|Centrifugation Extracellular vesicles 2497 34329193 Homo sapiens CircRNA circFOXK2 facilitates oncogenesis in breast cancer via IGF2BP3/miR-370 axis Breast cancer cells cl BT-549 Protein|miRNA|circRNA Western blotting|qRT-PCR 2021 Total Exosome Isolation Reagent Exosomes 2498 34329193 Homo sapiens CircRNA circFOXK2 facilitates oncogenesis in breast cancer via IGF2BP3/miR-370 axis Breast cancer cells cl BT-549-H (high metastatic potential) Protein|miRNA|circRNA Western blotting|qRT-PCR 2021 Total Exosome Isolation Reagent Exosomes 2499 34329193 Homo sapiens CircRNA circFOXK2 facilitates oncogenesis in breast cancer via IGF2BP3/miR-370 axis Breast cancer cells cl BT-549 miRNA qRT-PCR 2021 Total Exosome Isolation Reagent Exosomes 2500 34329193 Homo sapiens CircRNA circFOXK2 facilitates oncogenesis in breast cancer via IGF2BP3/miR-370 axis Breast cancer cells cl BT-549 miRNA qRT-PCR 2021 Total Exosome Isolation Reagent Exosomes 2501 34329193 Homo sapiens CircRNA circFOXK2 facilitates oncogenesis in breast cancer via IGF2BP3/miR-370 axis Breast cancer cells cl BT-549 miRNA qRT-PCR 2021 Total Exosome Isolation Reagent Exosomes 2502 34322205 Homo sapiens Molecular evaluation of five different isolation methods for extracellular vesicles reveals different clinical applicability and subcellular origin Monocytic leukemia cells cl MM6 - ExoQuick Ultra Protein Flow cytometry|Mass spectometry 2021 ExoQuick Kit Extracellular vesicles 2503 34322205 Homo sapiens Molecular evaluation of five different isolation methods for extracellular vesicles reveals different clinical applicability and subcellular origin Monocytic leukemia cells cl MM6 - exoEasy Protein Flow cytometry|Mass spectometry 2021 exoEasy Maxi Kit Extracellular vesicles 2504 34322205 Homo sapiens Molecular evaluation of five different isolation methods for extracellular vesicles reveals different clinical applicability and subcellular origin Monocytic leukemia cells cl MM6 - iZON 35 nm column Protein Flow cytometry|Mass spectometry 2021 Size exclusion chromatography|Centrifugal ultrafiltration Extracellular vesicles 2505 34322205 Homo sapiens Molecular evaluation of five different isolation methods for extracellular vesicles reveals different clinical applicability and subcellular origin Monocytic leukemia cells cl MM6 - iZON 70 nm column Protein Flow cytometry|Mass spectometry 2021 Size exclusion chromatography|Centrifugal ultrafiltration Extracellular vesicles 2506 34322205 Homo sapiens Molecular evaluation of five different isolation methods for extracellular vesicles reveals different clinical applicability and subcellular origin Monocytic leukemia cells cl MM6 - OptiPrep Protein Flow cytometry|Mass spectometry 2021 OptiPrep density gradient centrifugation|Ultracentrifugation Extracellular vesicles 2507 34322206 Homo sapiens Molecular evaluation of five different isolation methods for extracellular vesicles reveals different clinical applicability and subcellular origin Monocytic leukemia cells cl MM6 - MagCapture Protein Flow cytometry|Mass spectometry 2021 MagCapture Exosome Isolation Kit PS Extracellular vesicles 2508 34322205 Homo sapiens Molecular evaluation of five different isolation methods for extracellular vesicles reveals different clinical applicability and subcellular origin Monocytic leukemia cells cl MM6 - iZON 35 nm column flow-through fraction Protein Flow cytometry|Mass spectometry 2021 Size exclusion chromatography|Centrifugal ultrafiltration Extracellular vesicles 2509 34322205 Homo sapiens Molecular evaluation of five different isolation methods for extracellular vesicles reveals different clinical applicability and subcellular origin Monocytic leukemia cells cl MM6 - iZON 70 nm column flow-through fraction Protein Flow cytometry|Mass spectometry 2021 Size exclusion chromatography|Centrifugal ultrafiltration Extracellular vesicles 2510 34322205 Homo sapiens Molecular evaluation of five different isolation methods for extracellular vesicles reveals different clinical applicability and subcellular origin Monocytic leukemia cells cl MM6 - OptiPrep high density fraction Protein Flow cytometry 2021 OptiPrep density gradient centrifugation|Ultracentrifugation Extracellular vesicles 2511 34322205 Homo sapiens Molecular evaluation of five different isolation methods for extracellular vesicles reveals different clinical applicability and subcellular origin Monocytic leukemia cells cl MM6 - OptiPrep low density fraction Protein Flow cytometry 2021 OptiPrep density gradient centrifugation|Ultracentrifugation Extracellular vesicles 2512 34322205 Homo sapiens Molecular evaluation of five different isolation methods for extracellular vesicles reveals different clinical applicability and subcellular origin Plasma ts Plasma - ExoQuick Ultra Protein Flow cytometry|Mass spectometry 2021 ExoQuick Kit Extracellular vesicles 2513 34322205 Homo sapiens Molecular evaluation of five different isolation methods for extracellular vesicles reveals different clinical applicability and subcellular origin Plasma ts Plasma - exoEasy Protein Flow cytometry|Mass spectometry 2021 exoEasy Maxi Kit Extracellular vesicles 2514 34322205 Homo sapiens Molecular evaluation of five different isolation methods for extracellular vesicles reveals different clinical applicability and subcellular origin Plasma ts Plasma - iZON 35 nm column Protein Flow cytometry|Mass spectometry 2021 Size exclusion chromatography Extracellular vesicles 2515 34322205 Homo sapiens Molecular evaluation of five different isolation methods for extracellular vesicles reveals different clinical applicability and subcellular origin Plasma ts Plasma - iZON 70 nm column Protein Mass spectometry 2021 Size exclusion chromatography Extracellular vesicles 2516 34322205 Homo sapiens Molecular evaluation of five different isolation methods for extracellular vesicles reveals different clinical applicability and subcellular origin Plasma ts Plasma - OptiPrep Protein Flow cytometry|Mass spectometry 2021 OptiPrep density gradient centrifugation|Ultracentrifugation Extracellular vesicles 2517 34322205 Homo sapiens Molecular evaluation of five different isolation methods for extracellular vesicles reveals different clinical applicability and subcellular origin Plasma ts Plasma - iZON 35 nm column flow-through fraction Protein Flow cytometry|Mass spectometry 2021 Size exclusion chromatography Extracellular vesicles 2518 34322205 Homo sapiens Molecular evaluation of five different isolation methods for extracellular vesicles reveals different clinical applicability and subcellular origin Plasma ts Plasma - iZON 70 nm column flow-through fraction Protein Flow cytometry|Mass spectometry 2021 Size exclusion chromatography Extracellular vesicles 2519 34322205 Homo sapiens Molecular evaluation of five different isolation methods for extracellular vesicles reveals different clinical applicability and subcellular origin Plasma ts Plasma - OptiPrep high density fraction Protein Flow cytometry 2021 OptiPrep density gradient centrifugation|Ultracentrifugation Extracellular vesicles 2520 34322205 Homo sapiens Molecular evaluation of five different isolation methods for extracellular vesicles reveals different clinical applicability and subcellular origin Plasma ts Plasma - OptiPrep low density fraction Protein Flow cytometry 2021 OptiPrep density gradient centrifugation|Ultracentrifugation Extracellular vesicles 2521 34315885 Mus musculus Extracellular vesicles and exosomes generated from cystic renal epithelial cells promote cyst growth in autosomal dominant polycystic kidney disease Kidney epithelial cells cl PN24 - postnatal homozygous Pkd1-null Protein|miRNA Western blotting|Immuno-EM|qRT-PCR 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2522 34315885 Mus musculus Extracellular vesicles and exosomes generated from cystic renal epithelial cells promote cyst growth in autosomal dominant polycystic kidney disease Kidney epithelial cells cl PH2 - postnatal heterozygous Pkd1 Protein|miRNA Western blotting|qRT-PCR 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2523 34315885 Homo sapiens Extracellular vesicles and exosomes generated from cystic renal epithelial cells promote cyst growth in autosomal dominant polycystic kidney disease Urine ts Urine - healthy volunteers Protein Western blotting 2021 Centrifugation|Ultracentrifugation Exosomes 2524 34315885 Homo sapiens Extracellular vesicles and exosomes generated from cystic renal epithelial cells promote cyst growth in autosomal dominant polycystic kidney disease Urine ts Urine - autosomal dominant polycystic kidney disease patients Protein Western blotting 2021 Centrifugation|Ultracentrifugation Exosomes 2525 34315885 Mus musculus Extracellular vesicles and exosomes generated from cystic renal epithelial cells promote cyst growth in autosomal dominant polycystic kidney disease Embryonic kidney cells cl MEK - Pkd1 WT Protein|miRNA Western blotting|qRT-PCR 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2526 34315885 Mus musculus Extracellular vesicles and exosomes generated from cystic renal epithelial cells promote cyst growth in autosomal dominant polycystic kidney disease Embryonic kidney cells cl MEK - Pkd1-null Protein|miRNA Western blotting|qRT-PCR 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2527 34315885 Mus musculus Extracellular vesicles and exosomes generated from cystic renal epithelial cells promote cyst growth in autosomal dominant polycystic kidney disease Kidney epithelial cells cl PN24 - postnatal homozygous Pkd1-null Protein|miRNA Western blotting|qRT-PCR 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2528 34315885 Mus musculus Extracellular vesicles and exosomes generated from cystic renal epithelial cells promote cyst growth in autosomal dominant polycystic kidney disease Kidney epithelial cells cl PN24 - postnatal homozygous Pkd1-null Protein|miRNA Western blotting|qRT-PCR 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2529 34293122 Homo sapiens Platelet EVs contain an active proteasome involved in protein processing for antigen presentation via MHC-I molecules Platelets ts Platelets (thrombin-activated) - healthy volunteers Protein|Lipid Western blotting|Immuno-EM|Flow cytometry 2021 Centrifugation Extracellular vesicles 2530 34293122 Homo sapiens Platelet EVs contain an active proteasome involved in protein processing for antigen presentation via MHC-I molecules Platelets ts Platelets (thrombin-activated) - healthy volunteers Protein Flow cytometry 2021 Centrifugation Extracellular vesicles 2531 34293122 Homo sapiens Platelet EVs contain an active proteasome involved in protein processing for antigen presentation via MHC-I molecules Platelets ts Platelets (thrombin-activated) - healthy volunteers Protein Flow cytometry 2021 Centrifugation Extracellular vesicles 2532 34293122 Homo sapiens Platelet EVs contain an active proteasome involved in protein processing for antigen presentation via MHC-I molecules Platelets ts Platelets (thrombin-activated) - healthy volunteers Protein Flow cytometry 2021 Centrifugation Extracellular vesicles 2533 34293122 Homo sapiens Platelet EVs contain an active proteasome involved in protein processing for antigen presentation via MHC-I molecules Platelets ts Platelets (thrombin-activated) - healthy volunteers Protein Flow cytometry 2021 Centrifugation Extracellular vesicles 2534 34293122 Homo sapiens Platelet EVs contain an active proteasome involved in protein processing for antigen presentation via MHC-I molecules Platelets ts Platelets (thrombin-activated) - healthy volunteers Protein Flow cytometry 2021 Centrifugation Extracellular vesicles 2535 34293122 Homo sapiens Platelet EVs contain an active proteasome involved in protein processing for antigen presentation via MHC-I molecules Platelets ts Platelets (ADP-activated) - healthy volunteers Protein Flow cytometry 2021 Centrifugation Extracellular vesicles 2536 34293122 Homo sapiens Platelet EVs contain an active proteasome involved in protein processing for antigen presentation via MHC-I molecules Platelets ts Platelets (CRP-XL-activated) - healthy volunteers Protein Flow cytometry 2021 Centrifugation Extracellular vesicles 2537 34293122 Homo sapiens Platelet EVs contain an active proteasome involved in protein processing for antigen presentation via MHC-I molecules Platelets ts Platelets (HA-IgG-activated) - healthy volunteers Protein Flow cytometry 2021 Centrifugation Extracellular vesicles 2538 34293122 Mus musculus Platelet EVs contain an active proteasome involved in protein processing for antigen presentation via MHC-I molecules Platelets ts Platelets collected using 20% acid citrate dextrose Protein|Lipid Flow cytometry 2021 Centrifugation Extracellular vesicles 2539 34293122 Mus musculus Platelet EVs contain an active proteasome involved in protein processing for antigen presentation via MHC-I molecules Platelets ts Platelets collected using 20% acid citrate dextrose Protein Flow cytometry 2021 Centrifugation Extracellular vesicles 2540 34293122 Mus musculus Platelet EVs contain an active proteasome involved in protein processing for antigen presentation via MHC-I molecules Platelets ts Platelets collected using citrated tubes Protein|Lipid Flow cytometry 2021 Centrifugation Extracellular vesicles 2541 34293122 Mus musculus Platelet EVs contain an active proteasome involved in protein processing for antigen presentation via MHC-I molecules Platelets ts Platelets collected using 20% acid citrate dextrose Protein|Lipid Flow cytometry 2021 Centrifugation Extracellular vesicles 2542 34293122 Mus musculus Platelet EVs contain an active proteasome involved in protein processing for antigen presentation via MHC-I molecules Platelets ts Platelets collected using 20% acid citrate dextrose Protein|Lipid Flow cytometry 2021 Centrifugation Extracellular vesicles 2543 31819794 Homo sapiens Extracellular vesicles containing oncogenic mutant β-catenin activate Wnt signalling pathway in the recipient cells Colorectal cancer cells cl LIM1215 Protein Mass spectrometry|Western blotting 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2544 31819794 Homo sapiens Extracellular vesicles containing oncogenic mutant β-catenin activate Wnt signalling pathway in the recipient cells Colorectal cancer cells cl LIM1215 Protein Western blotting 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2545 31819794 Homo sapiens Extracellular vesicles containing oncogenic mutant β-catenin activate Wnt signalling pathway in the recipient cells Colorectal cancer cells cl LIM1215 - 10K pellet Protein Western blotting 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2546 31819794 Homo sapiens Extracellular vesicles containing oncogenic mutant β-catenin activate Wnt signalling pathway in the recipient cells Colorectal cancer cells cl LIM1215 - fraction 4 Protein Western blotting 2019 Differential centrifugation|OptiPrep density gradient centrifugation|Ultracentrifugation Extracellular vesicles 2547 31819794 Homo sapiens Extracellular vesicles containing oncogenic mutant β-catenin activate Wnt signalling pathway in the recipient cells Colorectal cancer cells cl LIM1215 - fraction 5 Protein Western blotting 2019 Differential centrifugation|OptiPrep density gradient centrifugation|Ultracentrifugation Extracellular vesicles 2548 31819794 Homo sapiens Extracellular vesicles containing oncogenic mutant β-catenin activate Wnt signalling pathway in the recipient cells Colorectal cancer cells cl LIM1215 - fraction 6 Protein Western blotting 2019 Differential centrifugation|OptiPrep density gradient centrifugation|Ultracentrifugation Extracellular vesicles 2549 31819794 Homo sapiens Extracellular vesicles containing oncogenic mutant β-catenin activate Wnt signalling pathway in the recipient cells Colorectal cancer cells cl LIM1215 - fraction 7 Protein Western blotting 2019 Differential centrifugation|OptiPrep density gradient centrifugation|Ultracentrifugation Extracellular vesicles 2550 31819794 Homo sapiens Extracellular vesicles containing oncogenic mutant β-catenin activate Wnt signalling pathway in the recipient cells Colorectal cancer cells cl LIM1215 - fraction 8 Protein Western blotting 2019 Differential centrifugation|OptiPrep density gradient centrifugation|Ultracentrifugation Extracellular vesicles 2551 31819794 Homo sapiens Extracellular vesicles containing oncogenic mutant β-catenin activate Wnt signalling pathway in the recipient cells Colorectal cancer cells cl LIM1215 - fraction 9 Protein Western blotting 2019 Differential centrifugation|OptiPrep density gradient centrifugation|Ultracentrifugation Extracellular vesicles 2552 31819794 Homo sapiens Extracellular vesicles containing oncogenic mutant β-catenin activate Wnt signalling pathway in the recipient cells Colorectal cancer cells cl LIM1215 - fraction 10 Protein Western blotting 2019 Differential centrifugation|OptiPrep density gradient centrifugation|Ultracentrifugation Extracellular vesicles 2553 31819794 Homo sapiens Extracellular vesicles containing oncogenic mutant β-catenin activate Wnt signalling pathway in the recipient cells Colorectal cancer cells cl HCT116 Protein Western blotting 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2554 31819794 Homo sapiens Extracellular vesicles containing oncogenic mutant β-catenin activate Wnt signalling pathway in the recipient cells Colorectal cancer cells cl LIM1889 Protein Western blotting 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2555 31819794 Homo sapiens Extracellular vesicles containing oncogenic mutant β-catenin activate Wnt signalling pathway in the recipient cells Colorectal cancer cells cl LIM2551 Protein Western blotting 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2556 31819794 Homo sapiens Extracellular vesicles containing oncogenic mutant β-catenin activate Wnt signalling pathway in the recipient cells Colorectal cancer cells cl CACO2 Protein Western blotting 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2557 31819794 Homo sapiens Extracellular vesicles containing oncogenic mutant β-catenin activate Wnt signalling pathway in the recipient cells Colorectal cancer cells cl COLO205 Protein Western blotting 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2558 31819794 Homo sapiens Extracellular vesicles containing oncogenic mutant β-catenin activate Wnt signalling pathway in the recipient cells Colorectal cancer cells cl LIM2405 Protein Western blotting 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2559 31819794 Homo sapiens Extracellular vesicles containing oncogenic mutant β-catenin activate Wnt signalling pathway in the recipient cells Colorectal cancer cells cl LIM2537 Protein Western blotting 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2560 31819794 Homo sapiens Extracellular vesicles containing oncogenic mutant β-catenin activate Wnt signalling pathway in the recipient cells Colorectal cancer cells cl LIM1863 Protein Western blotting 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2561 31819794 Homo sapiens Extracellular vesicles containing oncogenic mutant β-catenin activate Wnt signalling pathway in the recipient cells Colorectal cancer cells cl SW480 Protein Western blotting 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2562 31819794 Homo sapiens Extracellular vesicles containing oncogenic mutant β-catenin activate Wnt signalling pathway in the recipient cells Colorectal cancer cells cl SW620 Protein Western blotting 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2563 31819794 Homo sapiens Extracellular vesicles containing oncogenic mutant β-catenin activate Wnt signalling pathway in the recipient cells Colorectal cancer cells cl HCA7 Protein Western blotting 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2564 31819794 Homo sapiens Extracellular vesicles containing oncogenic mutant β-catenin activate Wnt signalling pathway in the recipient cells Colorectal cancer cells cl LOVO Protein Western blotting 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2565 31819794 Homo sapiens Extracellular vesicles containing oncogenic mutant β-catenin activate Wnt signalling pathway in the recipient cells Colorectal cancer cells cl RKO Protein Western blotting 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2566 31819794 Homo sapiens Extracellular vesicles containing oncogenic mutant β-catenin activate Wnt signalling pathway in the recipient cells Colorectal cancer cells cl SW1463 Protein Western blotting 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2567 33805332 Bos taurus Temporal Quantitative Proteomics Analysis of Neuroblastoma Cells Treated with Bovine Milk-Derived Extracellular Vesicles Highlights the Anti-Proliferative Properties of Milk-Derived Extracellular Vesicles Bovine milk ts Commercial milk Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation|Filtration Extracellular vesicles 2568 35260554 Homo sapiens Tumor-derived extracellular vesicles shuttle c-Myc to promote gastric cancer growth and metastasis via the KCNQ1OT1/miR-556-3p/CLIC1 axis Gastric cancer cells cl SNU-1 Protein|mRNA Western blotting|RT-qPCR 2022 Centrifugation|ExoQuick Kit Extracellular vesicles 2569 35260554 Homo sapiens Tumor-derived extracellular vesicles shuttle c-Myc to promote gastric cancer growth and metastasis via the KCNQ1OT1/miR-556-3p/CLIC1 axis Gastric cancer cells cl SNU-1 Protein Western blotting 2022 Centrifugation|ExoQuick Kit Extracellular vesicles 2570 35260554 Homo sapiens Tumor-derived extracellular vesicles shuttle c-Myc to promote gastric cancer growth and metastasis via the KCNQ1OT1/miR-556-3p/CLIC1 axis Gastric cancer cells cl SNU-1 Protein Western blotting 2022 Centrifugation|ExoQuick Kit Extracellular vesicles 2571 35689797 Homo sapiens Proteomic alterations in extracellular vesicles induced by oncogenic PIK3CA mutations Mammary epithelial cells cl MCF10A Protein Mass spectrometry 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2572 35689797 Homo sapiens Proteomic alterations in extracellular vesicles induced by oncogenic PIK3CA mutations Mammary epithelial cells cl MCF10A Protein Mass spectrometry 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2573 35689797 Homo sapiens Proteomic alterations in extracellular vesicles induced by oncogenic PIK3CA mutations Mammary epithelial cells cl MCF10A Protein Mass spectrometry 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2574 35136055 Homo sapiens Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells Lung cancer cells cl NCI-H226 Protein|miRNA Western blotting|miRNA array 2022 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2575 35136055 Homo sapiens Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells Lung cancer cells cl NCI-H226 Protein|miRNA Western blotting|miRNA array 2022 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2576 35136055 Homo sapiens Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells Lung cancer cells cl BZR Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2577 35136055 Homo sapiens Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells Lung cancer cells cl BZR Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2578 35136055 Homo sapiens Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells Lung cancer cells cl A549 miRNA RT-qPCR 2022 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2579 35136055 Homo sapiens Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells Lung cancer cells cl A549 Protein|miRNA Western blotting|RT-qPCR 2022 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2580 35136055 Homo sapiens Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells Lung cancer cells cl NCI-H1703 Protein|miRNA Western blotting|RT-qPCR 2022 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2581 35136055 Homo sapiens Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells Lung cancer cells cl NCI-H1703 Protein|miRNA Western blotting|RT-qPCR 2022 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2582 35136055 Homo sapiens Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells Lung cancer cells cl NCI-H1703 Protein|miRNA Western blotting|RT-qPCR 2022 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2583 35136055 Homo sapiens Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells Lung epithelial cells cl BEAS-2B Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2584 35136055 Homo sapiens Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells Lung epithelial cells cl BEAS-2B Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2585 35136055 Homo sapiens Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells Lung epithelial cells cl BEAS-2B Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2586 35136055 Homo sapiens Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells Lung cancer cells cl Calu-3 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2587 35136055 Homo sapiens Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells Lung cancer cells cl Calu-3 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2588 35136055 Homo sapiens Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells Lung cancer cells cl NCI-H1703 miRNA RT- qPCR 2022 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2589 35136055 Homo sapiens Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells Lung cancer cells cl NCI-H358 miRNA RT- qPCR 2022 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2590 35136055 Homo sapiens Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells Lung cancer cells cl A549 miRNA RT- qPCR 2022 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2591 35136055 Homo sapiens Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells Lung cancer cells cl NCI-H226 miRNA RT- qPCR 2022 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2592 35136055 Homo sapiens Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells Lung cancer cells cl NCI-H1299 miRNA RT- qPCR 2022 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2593 35136055 Homo sapiens Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells Lung epithelial cells cl BEAS-2B miRNA RT- qPCR 2022 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2594 35136055 Homo sapiens Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells Lung cancer cells cl BZR miRNA RT- qPCR 2022 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2595 35136055 Homo sapiens Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells Lung cancer cells cl BZR miRNA RT- qPCR 2022 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2596 35136055 Homo sapiens Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells Lung epithelial cells cl BEAS-2B miRNA RT- qPCR 2022 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2597 35136055 Homo sapiens Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells Lung epithelial cells cl BEAS-2B miRNA RT- qPCR 2022 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2598 35136055 Homo sapiens Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells Lung cancer cells cl NCI-H1299 miRNA RT- qPCR 2022 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2599 35136055 Homo sapiens Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells Lung cancer cells cl NCI-H1299 miRNA RT- qPCR 2022 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2600 35136055 Mus musculus Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells Lung cancer cells cl LLC miRNA RT- qPCR 2022 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2601 35351860 Homo sapiens Bone marrow mesenchymal stem cell-derived exosomal microRNA-381-3p alleviates vascular calcification in chronic kidney disease by targeting NFAT5 Bone marrow mesenchymal stem cells cl BMSC Protein|miRNA Western blotting|RT-qPCR 2022 Differential centrifugation|Ultracentrifugation Exosomes 2602 35351860 Homo sapiens Bone marrow mesenchymal stem cell-derived exosomal microRNA-381-3p alleviates vascular calcification in chronic kidney disease by targeting NFAT5 Bone marrow mesenchymal stem cells cl BMSC miRNA RT-qPCR 2022 Differential centrifugation|Ultracentrifugation Exosomes 2603 35654787 Homo sapiens CircSCAF8 promotes growth and metastasis of prostate cancer through the circSCAF8-miR-140-3p/miR-335-LIF pathway Urine ts Prostate cancer patients circRNA RT-qPCR 2022 Differential centrifugation|Ultracentrifugation|ExoQuick Kit Extracellular vesicles 2604 35654787 Homo sapiens CircSCAF8 promotes growth and metastasis of prostate cancer through the circSCAF8-miR-140-3p/miR-335-LIF pathway Urine ts Benign prostatic hyperplasia patients circRNA RT-qPCR 2022 Differential centrifugation|Ultracentrifugation|ExoQuick Kit Extracellular vesicles 2605 36581340 Homo sapiens Rab27b, a Regulator of Exosome Secretion, Is Associated With Peritoneal Metastases in Gastric Cancer Gastric cancer cells cl 58As9 Protein Western blotting 2023 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 2606 36581340 Homo sapiens Rab27b, a Regulator of Exosome Secretion, Is Associated With Peritoneal Metastases in Gastric Cancer Gastric cancer cells cl 58As9 Protein Western blotting 2023 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 2607 36581340 Homo sapiens Rab27b, a Regulator of Exosome Secretion, Is Associated With Peritoneal Metastases in Gastric Cancer Gastric cancer cells cl 58As9 Protein Western blotting 2023 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 2608 32383290 Ovis aries Quantitative Proteomic Analysis of Seminal Plasma, Sperm Membrane Proteins, and Seminal Extracellular Vesicles Suggests Vesicular Mechanisms Aid in the Removal and Addition of Proteins to the Ram Sperm Membrane Seminal plasma ts Fraction B1 isolated from 10/20% iodixanol interface Protein Mass spectrometry 2020 Differential centrifugation|OptiPrep density gradient centrifugation|Ultracentrifugation Extracellular vesicles 2609 32383290 Ovis aries Quantitative Proteomic Analysis of Seminal Plasma, Sperm Membrane Proteins, and Seminal Extracellular Vesicles Suggests Vesicular Mechanisms Aid in the Removal and Addition of Proteins to the Ram Sperm Membrane Seminal plasma ts Fraction B2 isolated from 20/40% iodixanol interface Protein Mass spectrometry 2020 Differential centrifugation|OptiPrep density gradient centrifugation|Ultracentrifugation Extracellular vesicles 2610 30788085 Homo sapiens Extracellular vesicles derived from cancer-associated fibroblasts induce the migration and invasion of oral squamous cell carcinoma Oral mucosa ts Cancer-associated fibroblasts (CAFs) - oral squamous cell carcinoma Protein Western blotting|Immuno-EM|Mass spectrometry 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2611 30788085 Homo sapiens Extracellular vesicles derived from cancer-associated fibroblasts induce the migration and invasion of oral squamous cell carcinoma Oral mucosa ts Normal fibroblasts (NOFs) - healthy oral mucosa Protein Western blotting|Immuno-EM|Mass spectrometry 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2612 35443745 Homo sapiens Exosomal miR-146a-5p and miR-155-5p promote CXCL12/CXCR7-induced metastasis of colorectal cancer by crosstalk with cancer-associated fibroblasts Colorectal cancer cells cl HCT116 Protein|miRNA Western blotting|RNA sequencing|RT-qPCR 2022 Ultracentrifugation|ExoQuick Kit Exosomes 2613 35443745 Homo sapiens Exosomal miR-146a-5p and miR-155-5p promote CXCL12/CXCR7-induced metastasis of colorectal cancer by crosstalk with cancer-associated fibroblasts Colorectal cancer cells cl HCT116 Protein|miRNA Western blotting|RNA sequencing|RT-qPCR 2022 Ultracentrifugation|ExoQuick Kit Exosomes 2614 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - apical Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2615 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - apical Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2616 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - apical Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2617 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - apical Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2618 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - basolateral Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2619 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - basolateral Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2620 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - basolateral Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2621 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - basolateral Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2622 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - apical Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2623 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - apical Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2624 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - basolateral Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2625 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - basolateral Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2626 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - apical Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2627 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - apical Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2628 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - basolateral Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2629 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - basolateral Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2630 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - apical Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2631 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - apical Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2632 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - apical Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2633 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - apical Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2634 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - basolateral Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2635 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - basolateral Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2636 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - basolateral Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2637 35649370 Homo sapiens Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - basolateral Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2638 35649370 Homo sapiens Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Cervical cancer cells cl HeLa Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2639 35649370 Homo sapiens Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Cervical cancer cells cl HeLa Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2640 35649370 Homo sapiens Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Cervical cancer cells cl HeLa Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2641 35649370 Homo sapiens Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Cervical cancer cells cl HeLa Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2642 35649370 Homo sapiens Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Mammary epithelial cells cl MCF10A Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2643 35649370 Homo sapiens Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Mammary epithelial cells cl MCF10A Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2644 35649370 Homo sapiens Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Mammary epithelial cells cl MCF10A Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2645 35649370 Homo sapiens Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Mammary epithelial cells cl MCF10A Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2646 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - apical Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2647 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - apical Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2648 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - apical Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2649 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - apical Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2650 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - basolateral Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2651 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - basolateral Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2652 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - basolateral Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2653 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - basolateral Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2654 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - apical Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2655 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - apical Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2656 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - apical Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2657 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - basolateral Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2658 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - basolateral Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2659 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - basolateral Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2660 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - apical Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2661 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - basolateral Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2662 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - apical Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2663 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - apical Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2664 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - basolateral Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2665 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - basolateral Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2666 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - apical Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2667 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - apical Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2668 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - basolateral Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2669 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - basolateral Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2670 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - apical Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2671 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - apical Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2672 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - apical Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2673 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - basolateral Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2674 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - basolateral Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2675 35649370 Canis lupus familiaris Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells Kidney epithelial cells cl MDCK II - basolateral Protein Western blotting 2022 Differential centrifugation|Filtration|Immunoaffinity capture|Ultracentrifugation Exosomes 2676 35656858 Homo sapiens A multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells Pancreatic duct epithelial cells cl hTERT-HPNE Protein|Lipid|Metabolite Western blotting|Mass spectrometry 2022 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 2677 35656858 Homo sapiens A multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells Pancreatic duct epithelial cells cl HPDE-H6c7 Protein|Lipid|Metabolite Western blotting|Mass spectrometry 2022 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 2678 35656858 Homo sapiens A multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells Pancreatic cancer cells cl PANC-1 Protein|Lipid|Metabolite Western blotting|Mass spectrometry 2022 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 2679 35656858 Homo sapiens A multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells Pancreatic cancer cells cl MiaPaCa-2 Protein|Lipid|Metabolite Western blotting|Mass spectrometry 2022 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 2680 35656858 Homo sapiens A multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells Pancreatic cancer cells cl Capan-1 Protein|Lipid|Metabolite Western blotting|Mass spectrometry 2022 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 2681 35656858 Homo sapiens A multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells Pancreatic cancer cells cl SW-1990 Protein|Lipid|Metabolite Western blotting|Mass spectrometry 2022 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 2682 35656858 Homo sapiens A multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells Pancreatic cancer cells cl PPCL-68 (PDX) Protein|Lipid|Metabolite Western blotting|Mass spectrometry 2022 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 2683 35656858 Homo sapiens A multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells Pancreatic cancer cells cl PPCL-46 (PDX) Protein|Lipid|Metabolite Western blotting|Mass spectrometry 2022 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 2684 35656858 Homo sapiens A multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells Pancreatic duct epithelial cells cl hTERT-HPNE Protein Mass spectrometry 2022 EVtrap Extracellular vesicles 2685 35656858 Homo sapiens A multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells Pancreatic duct epithelial cells cl HPDE-H6c7 Protein Mass spectrometry 2022 EVtrap Extracellular vesicles 2686 35656858 Homo sapiens A multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells Pancreatic cancer cells cl PANC-1 Protein Mass spectrometry 2022 EVtrap Extracellular vesicles 2687 35656858 Homo sapiens A multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells Pancreatic cancer cells cl MiaPaCa-2 Protein Mass spectrometry 2022 EVtrap Extracellular vesicles 2688 35656858 Homo sapiens A multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells Pancreatic cancer cells cl Capan-1 Protein Mass spectrometry 2022 EVtrap Extracellular vesicles 2689 35656858 Homo sapiens A multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells Pancreatic cancer cells cl SW-1990 Protein Mass spectrometry 2022 EVtrap Extracellular vesicles 2690 35656858 Homo sapiens A multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells Pancreatic cancer cells cl PPCL-68 (PDX) Protein Mass spectrometry 2022 EVtrap Extracellular vesicles 2691 35656858 Homo sapiens A multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells Pancreatic cancer cells cl PPCL-46 (PDX) Protein Mass spectrometry 2022 EVtrap Extracellular vesicles 2692 35210436 Homo sapiens M1 macrophage-derived exosomes and their key molecule lncRNA HOTTIP suppress head and neck squamous cell carcinoma progression by upregulating the TLR5/NF-κB pathway Macrophage cl M0 macrophage (THP-1) Protein|mRNA Western blotting|RT-qPCR 2022 Total Exosome Isolation Reagent Exosomes 2693 35210436 Homo sapiens M1 macrophage-derived exosomes and their key molecule lncRNA HOTTIP suppress head and neck squamous cell carcinoma progression by upregulating the TLR5/NF-κB pathway Macrophage cl M1 macrophage (THP-1) Protein|mRNA Western blotting|RT-qPCR 2022 Total Exosome Isolation Reagent Exosomes 2694 35210436 Homo sapiens M1 macrophage-derived exosomes and their key molecule lncRNA HOTTIP suppress head and neck squamous cell carcinoma progression by upregulating the TLR5/NF-κB pathway Macrophage cl M2 macrophage (THP-1) Protein|mRNA Western blotting|RT-qPCR 2022 Total Exosome Isolation Reagent Exosomes 2695 35210436 Homo sapiens M1 macrophage-derived exosomes and their key molecule lncRNA HOTTIP suppress head and neck squamous cell carcinoma progression by upregulating the TLR5/NF-κB pathway Macrophage cl M1 macrophage (THP-1) mRNA RT-qPCR 2022 Total Exosome Isolation Reagent Exosomes 2696 35210436 Homo sapiens M1 macrophage-derived exosomes and their key molecule lncRNA HOTTIP suppress head and neck squamous cell carcinoma progression by upregulating the TLR5/NF-κB pathway Macrophage cl M1 macrophage (THP-1) mRNA RT-qPCR 2022 Total Exosome Isolation Reagent Exosomes 2697 35210436 Homo sapiens M1 macrophage-derived exosomes and their key molecule lncRNA HOTTIP suppress head and neck squamous cell carcinoma progression by upregulating the TLR5/NF-κB pathway Macrophage cl M1 macrophage (THP-1) mRNA RT-qPCR 2022 Total Exosome Isolation Reagent Exosomes 2698 35210436 Homo sapiens M1 macrophage-derived exosomes and their key molecule lncRNA HOTTIP suppress head and neck squamous cell carcinoma progression by upregulating the TLR5/NF-κB pathway Macrophage cl M1 macrophage (THP-1) mRNA RT-qPCR 2022 Total Exosome Isolation Reagent Exosomes 2699 35333565 Homo sapiens LAMP2A regulates the loading of proteins into exosomes Retinal pigment epithelial cells cl ARPE-19 Protein Western blotting|Mass spectrometry 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2700 35333565 Homo sapiens LAMP2A regulates the loading of proteins into exosomes Retinal pigment epithelial cells cl ARPE-19 Protein Western blotting|Mass spectrometry 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2701 35333565 Homo sapiens LAMP2A regulates the loading of proteins into exosomes Retinal pigment epithelial cells cl ARPE-19 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2702 35333565 Homo sapiens LAMP2A regulates the loading of proteins into exosomes Retinal pigment epithelial cells cl ARPE-19 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2703 35333565 Homo sapiens LAMP2A regulates the loading of proteins into exosomes Retinal pigment epithelial cells cl ARPE-19 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2704 35333565 Homo sapiens LAMP2A regulates the loading of proteins into exosomes Retinal pigment epithelial cells cl ARPE-19 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2705 35333565 Homo sapiens LAMP2A regulates the loading of proteins into exosomes Retinal pigment epithelial cells cl ARPE-19 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2706 35333565 Homo sapiens LAMP2A regulates the loading of proteins into exosomes Retinal pigment epithelial cells cl ARPE-19 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2707 35333565 Homo sapiens LAMP2A regulates the loading of proteins into exosomes Retinal pigment epithelial cells cl ARPE-19 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2708 35333565 Homo sapiens LAMP2A regulates the loading of proteins into exosomes Retinal pigment epithelial cells cl ARPE-19 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2709 35333565 Homo sapiens LAMP2A regulates the loading of proteins into exosomes Retinal pigment epithelial cells cl ARPE-19 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2710 35333565 Homo sapiens LAMP2A regulates the loading of proteins into exosomes Retinal pigment epithelial cells cl ARPE-19 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2711 35333565 Homo sapiens LAMP2A regulates the loading of proteins into exosomes Kidney cancer cells cl 769-P Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2712 35333565 Homo sapiens LAMP2A regulates the loading of proteins into exosomes Kidney cancer cells cl 769-P Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2713 35333565 Homo sapiens LAMP2A regulates the loading of proteins into exosomes Retinal pigment epithelial cells cl ARPE-19 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2714 35333565 Homo sapiens LAMP2A regulates the loading of proteins into exosomes Retinal pigment epithelial cells cl ARPE-19 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2715 35333565 Homo sapiens LAMP2A regulates the loading of proteins into exosomes Retinal pigment epithelial cells cl ARPE-19 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2716 35333565 Homo sapiens LAMP2A regulates the loading of proteins into exosomes Retinal pigment epithelial cells cl ARPE-19 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2717 35333565 Homo sapiens LAMP2A regulates the loading of proteins into exosomes Retinal pigment epithelial cells cl ARPE-19 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2718 35333565 Homo sapiens LAMP2A regulates the loading of proteins into exosomes Retinal pigment epithelial cells cl ARPE-19 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2719 35333565 Homo sapiens LAMP2A regulates the loading of proteins into exosomes Retinal pigment epithelial cells cl ARPE-19 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2720 35333565 Homo sapiens LAMP2A regulates the loading of proteins into exosomes Retinal pigment epithelial cells cl ARPE-19 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2721 35333565 Homo sapiens LAMP2A regulates the loading of proteins into exosomes Retinal pigment epithelial cells cl ARPE-19 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2722 35333565 Homo sapiens LAMP2A regulates the loading of proteins into exosomes Retinal pigment epithelial cells cl ARPE-19 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2723 35333565 Homo sapiens LAMP2A regulates the loading of proteins into exosomes Retinal pigment epithelial cells cl ARPE-19 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2724 35333565 Homo sapiens LAMP2A regulates the loading of proteins into exosomes Retinal pigment epithelial cells cl ARPE-19 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2725 35333565 Homo sapiens LAMP2A regulates the loading of proteins into exosomes Retinal pigment epithelial cells cl ARPE-19 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2726 35333565 Homo sapiens LAMP2A regulates the loading of proteins into exosomes Retinal pigment epithelial cells cl ARPE-19 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2727 35333565 Homo sapiens LAMP2A regulates the loading of proteins into exosomes Retinal pigment epithelial cells cl ARPE-19 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2728 35333565 Homo sapiens LAMP2A regulates the loading of proteins into exosomes Retinal pigment epithelial cells cl ARPE-19 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2729 35333565 Homo sapiens LAMP2A regulates the loading of proteins into exosomes Retinal pigment epithelial cells cl ARPE-19 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2730 35333565 Homo sapiens LAMP2A regulates the loading of proteins into exosomes Retinal pigment epithelial cells cl ARPE-19 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2731 35333565 Homo sapiens LAMP2A regulates the loading of proteins into exosomes Retinal pigment epithelial cells cl ARPE-19 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2732 35333565 Homo sapiens LAMP2A regulates the loading of proteins into exosomes Retinal pigment epithelial cells cl ARPE-19 Protein Western blotting 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2733 35545056 Mus musculus MDS cells impair osteolineage differentiation of MSCs via extracellular vesicles to suppress normal hematopoiesis Bone marrow cells ts C57BL/6J - control miRNA miRNA array 2022 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 2734 35545056 Mus musculus MDS cells impair osteolineage differentiation of MSCs via extracellular vesicles to suppress normal hematopoiesis Bone marrow cells ts C57BL/6J - MDS/AML (Abcg2 model) miRNA miRNA array 2022 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 2735 35545056 Mus musculus MDS cells impair osteolineage differentiation of MSCs via extracellular vesicles to suppress normal hematopoiesis Bone marrow cells ts C57BL/6J - WT miRNA miRNA array 2022 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 2736 35545056 Mus musculus MDS cells impair osteolineage differentiation of MSCs via extracellular vesicles to suppress normal hematopoiesis Bone marrow cells ts C57BL/6J - MDS/AML (NHD13Tg model) miRNA miRNA array 2022 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 2737 35545056 Homo sapiens MDS cells impair osteolineage differentiation of MSCs via extracellular vesicles to suppress normal hematopoiesis Serum ts Healthy miRNA miRNA array 2022 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 2738 35545056 Homo sapiens MDS cells impair osteolineage differentiation of MSCs via extracellular vesicles to suppress normal hematopoiesis Serum ts MDS patients miRNA miRNA array 2022 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 2739 35513391 Homo sapiens Small extracellular vesicle-mediated miR-320e transmission promotes osteogenesis in OPLL by targeting TAK1 Posterior longitudinal ligament ts Ossicifation of posterior longitudinal ligament cells Protein|miRNA Western blotting|RNA sequencing|qRT-PCR 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2740 35513391 Homo sapiens Small extracellular vesicle-mediated miR-320e transmission promotes osteogenesis in OPLL by targeting TAK1 Posterior longitudinal ligament ts Posterior longitudinal ligament cells miRNA RNA sequencing|qRT-PCR 2022 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2741 35173168 Mus musculus Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression Serum ts BALB/c bearing 4T07 primary tumour Protein|mRNA Western blotting|RNA sequencing|qRT-PCR 2022 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 2742 35173168 Mus musculus Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression Breast cancer cells cl|ts BALB/c bearing 4T07 primary tumour miRNA qRT-PCR 2022 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 2743 35173168 Mus musculus Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression Breast cancer cells cl|ts BALB/c bearing Lin28B overexpressed 4T07 primary tumour miRNA qRT-PCR 2022 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 2744 35173168 Mus musculus Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression Serum ts BALB/c bearing Lin28B overexpressed 4T07 primary tumour miRNA qRT-PCR 2022 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 2745 35173168 Mus musculus Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression Serum ts PyMT control mice miRNA qRT-PCR 2022 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 2746 35173168 Mus musculus Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression Serum ts PyMT Lin28B knockin mice miRNA qRT-PCR 2022 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 2747 35173168 Mus musculus Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression Serum ts MMTV-Neu control mice miRNA qRT-PCR 2022 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 2748 35173168 Mus musculus Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression Serum ts MMTV-Neu Lin28B knockin mice miRNA qRT-PCR 2022 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 2749 35173168 Homo sapiens Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression Serum ts Healthy miRNA qRT-PCR 2022 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 2750 35173168 Homo sapiens Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression Serum ts Breast cancer patients miRNA qRT-PCR 2022 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 2751 35173168 Homo sapiens Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression Serum ts TNBC breast cancer patients miRNA qRT-PCR 2022 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 2752 35173168 Homo sapiens Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression Serum ts Luminal breast cancer patients miRNA qRT-PCR 2022 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 2753 35173168 Homo sapiens Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression Serum ts HER2-positive breast cancer patients miRNA qRT-PCR 2022 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 2754 33432243 Homo sapiens Exosome detection via the ultrafast-isolation system: EXODUS Urine ts 10 -kPa Protein Western blotting 2021 Filtration|Exosome detection via ultrafast-isolation system (EXODUS) Exosomes 2755 33432243 Homo sapiens Exosome detection via the ultrafast-isolation system: EXODUS Urine ts 20 -kPa Protein Western blotting 2021 Filtration|Exosome detection via ultrafast-isolation system (EXODUS) Exosomes 2756 33432243 Homo sapiens Exosome detection via the ultrafast-isolation system: EXODUS Urine ts 30 -kPa Protein Western blotting 2021 Filtration|Exosome detection via ultrafast-isolation system (EXODUS) Exosomes 2757 33432243 Homo sapiens Exosome detection via the ultrafast-isolation system: EXODUS Urine ts 40 -kPa Protein Western blotting 2021 Filtration|Exosome detection via ultrafast-isolation system (EXODUS) Exosomes 2758 33432243 Homo sapiens Exosome detection via the ultrafast-isolation system: EXODUS Urine ts 50 -kPa Protein Western blotting 2021 Filtration|Exosome detection via ultrafast-isolation system (EXODUS) Exosomes 2759 33432243 Homo sapiens Exosome detection via the ultrafast-isolation system: EXODUS Urine ts Urine Protein Western blotting 2021 Tangential flow filtration Exosomes 2760 33432243 Homo sapiens Exosome detection via the ultrafast-isolation system: EXODUS Urine ts 10 sec conversion time Protein Western blotting 2021 Filtration|Exosome detection via ultrafast-isolation system (EXODUS) Exosomes 2761 33432243 Homo sapiens Exosome detection via the ultrafast-isolation system: EXODUS Urine ts 20 sec conversion time Protein Western blotting 2021 Filtration|Exosome detection via ultrafast-isolation system (EXODUS) Exosomes 2762 33432243 Homo sapiens Exosome detection via the ultrafast-isolation system: EXODUS Urine ts 30 sec conversion time Protein Western blotting 2021 Filtration|Exosome detection via ultrafast-isolation system (EXODUS) Exosomes 2763 33432243 Homo sapiens Exosome detection via the ultrafast-isolation system: EXODUS Urine ts 40 sec conversion time Protein Western blotting 2021 Filtration|Exosome detection via ultrafast-isolation system (EXODUS) Exosomes 2764 33432243 Homo sapiens Exosome detection via the ultrafast-isolation system: EXODUS Urine ts 50 sec conversion time Protein Western blotting 2021 Filtration|Exosome detection via ultrafast-isolation system (EXODUS) Exosomes 2765 33432243 Homo sapiens Exosome detection via the ultrafast-isolation system: EXODUS Urine ts Urine Protein Western blotting 2021 Tangential flow filtration Exosomes 2766 33432243 Homo sapiens Exosome detection via the ultrafast-isolation system: EXODUS Urine ts Urine Protein Western blotting 2021 Filtration|Exosome detection via ultrafast-isolation system (EXODUS) Exosomes 2767 33432243 Homo sapiens Exosome detection via the ultrafast-isolation system: EXODUS Urine ts Urine Protein Western blotting 2021 Filtration|Ultracentrifugation Exosomes 2768 33432243 Homo sapiens Exosome detection via the ultrafast-isolation system: EXODUS Urine ts Urine Protein Western blotting 2021 Filtration|Polyethylene glycol-based precipitation Exosomes 2769 33432243 Homo sapiens Exosome detection via the ultrafast-isolation system: EXODUS Urine ts Urine Protein Western blotting 2021 Filtration|Membrane affinity purification Exosomes 2770 33432243 Homo sapiens Exosome detection via the ultrafast-isolation system: EXODUS Urine ts Urine Protein Western blotting 2021 Filtration|Size exclusion chromatography Exosomes 2771 33432243 Homo sapiens Exosome detection via the ultrafast-isolation system: EXODUS Urine ts Urine Protein Western blotting 2021 Filtration|Phosphatidylserine affinity purification Exosomes 2772 33432243 Homo sapiens Exosome detection via the ultrafast-isolation system: EXODUS Saliva ts Saliva Protein Western blotting 2021 Filtration|Exosome detection via ultrafast-isolation system (EXODUS) Exosomes 2773 33432243 Homo sapiens Exosome detection via the ultrafast-isolation system: EXODUS Saliva ts Saliva Protein Western blotting 2021 Filtration|Ultracentrifugation Exosomes 2774 33432243 Homo sapiens Exosome detection via the ultrafast-isolation system: EXODUS Saliva ts Saliva Protein Western blotting 2021 Filtration|Polyethylene glycol-based precipitation Exosomes 2775 33432243 Homo sapiens Exosome detection via the ultrafast-isolation system: EXODUS Urine ts Fresh Protein Western blotting 2021 Filtration|Exosome detection via ultrafast-isolation system (EXODUS) Exosomes 2776 33432243 Homo sapiens Exosome detection via the ultrafast-isolation system: EXODUS Urine ts Stored at 4°C for 2 days Protein Western blotting 2021 Filtration|Exosome detection via ultrafast-isolation system (EXODUS) Exosomes 2777 33432243 Homo sapiens Exosome detection via the ultrafast-isolation system: EXODUS Urine ts Stored at -80°C Protein Western blotting 2021 Filtration|Exosome detection via ultrafast-isolation system (EXODUS) Exosomes 2778 35304471 Homo sapiens Aged bone matrix-derived extracellular vesicles as a messenger for calcification paradox Bone ts Young (27-31 year-old females) Protein Flow cytometry 2022 Differential centrifugation|Filtration|Ultracentrifugation|Centrifugal ultrafiltration|OptiPrep density gradient centrifugation Extracellular vesicles 2779 35304471 Homo sapiens Aged bone matrix-derived extracellular vesicles as a messenger for calcification paradox Bone ts Aged (67-73 year-old females) Protein Flow cytometry 2022 Differential centrifugation|Filtration|Ultracentrifugation|Centrifugal ultrafiltration|OptiPrep density gradient centrifugation Extracellular vesicles 2780 35304471 Mus musculus Aged bone matrix-derived extracellular vesicles as a messenger for calcification paradox Bone ts Osteocytes - C57BL/6J marrow-depleted femurs and tibias Protein Flow cytometry 2022 Differential centrifugation|Filtration|Ultracentrifugation|Centrifugal ultrafiltration|OptiPrep density gradient centrifugation Extracellular vesicles 2781 35304471 Mus musculus Aged bone matrix-derived extracellular vesicles as a messenger for calcification paradox Bone ts Osteoblasts - C57BL/6J marrow-depleted femurs and tibias Protein Flow cytometry 2022 Differential centrifugation|Filtration|Ultracentrifugation|Centrifugal ultrafiltration|OptiPrep density gradient centrifugation Extracellular vesicles 2782 35304471 Mus musculus Aged bone matrix-derived extracellular vesicles as a messenger for calcification paradox Hypertrophic chondrocytes cl ATDC5 - 21-day induction with chondrogenic medium Protein Flow cytometry 2022 Differential centrifugation|Filtration|Ultracentrifugation|Centrifugal ultrafiltration|OptiPrep density gradient centrifugation Extracellular vesicles 2783 35304471 Mus musculus Aged bone matrix-derived extracellular vesicles as a messenger for calcification paradox Bone ts Young (2 month-old) C57BL/6J femurs and tibias miRNA miRNA array 2022 ExoQuick Kit Extracellular vesicles 2784 35304471 Mus musculus Aged bone matrix-derived extracellular vesicles as a messenger for calcification paradox Bone ts Aged (18 month-old) C57BL/6J femurs and tibias miRNA miRNA array 2022 ExoQuick Kit Extracellular vesicles 2785 35304471 Mus musculus Aged bone matrix-derived extracellular vesicles as a messenger for calcification paradox Bone ts 2 month-old C57BL/6J femurs and tibias miRNA qRT-PCR 2022 Differential centrifugation|Filtration|Ultracentrifugation|Centrifugal ultrafiltration|OptiPrep density gradient centrifugation Extracellular vesicles 2786 35304471 Mus musculus Aged bone matrix-derived extracellular vesicles as a messenger for calcification paradox Bone ts 12 month-old C57BL/6J femurs and tibias miRNA qRT-PCR 2022 Differential centrifugation|Filtration|Ultracentrifugation|Centrifugal ultrafiltration|OptiPrep density gradient centrifugation Extracellular vesicles 2787 35304471 Mus musculus Aged bone matrix-derived extracellular vesicles as a messenger for calcification paradox Bone ts 18 month-old C57BL/6J femurs and tibias miRNA qRT-PCR 2022 Differential centrifugation|Filtration|Ultracentrifugation|Centrifugal ultrafiltration|OptiPrep density gradient centrifugation Extracellular vesicles 2788 35304471 Homo sapiens Aged bone matrix-derived extracellular vesicles as a messenger for calcification paradox Serum ts Young (27-31 year-old females) miRNA qRT-PCR 2022 Differential centrifugation|Filtration|Ultracentrifugation|Centrifugal ultrafiltration|OptiPrep density gradient centrifugation Extracellular vesicles 2789 35304471 Homo sapiens Aged bone matrix-derived extracellular vesicles as a messenger for calcification paradox Serum ts Aged (67-73 year-old females) miRNA qRT-PCR 2022 Differential centrifugation|Filtration|Ultracentrifugation|Centrifugal ultrafiltration|OptiPrep density gradient centrifugation Extracellular vesicles 2790 35304471 Mus musculus Aged bone matrix-derived extracellular vesicles as a messenger for calcification paradox Liver ts 2 month-old C57BL/6J miRNA qRT-PCR 2022 Differential centrifugation|Filtration|Ultracentrifugation|Centrifugal ultrafiltration|OptiPrep density gradient centrifugation Extracellular vesicles 2791 35304471 Mus musculus Aged bone matrix-derived extracellular vesicles as a messenger for calcification paradox Liver ts 18 month-old C57BL/6J miRNA qRT-PCR 2022 Differential centrifugation|Filtration|Ultracentrifugation|Centrifugal ultrafiltration|OptiPrep density gradient centrifugation Extracellular vesicles 2792 35304471 Mus musculus Aged bone matrix-derived extracellular vesicles as a messenger for calcification paradox Serum ts 2 month-old C57BL/6J miRNA qRT-PCR 2022 Differential centrifugation|Filtration|Ultracentrifugation|Centrifugal ultrafiltration|OptiPrep density gradient centrifugation Extracellular vesicles 2793 35304471 Mus musculus Aged bone matrix-derived extracellular vesicles as a messenger for calcification paradox Serum ts 18 month-old C57BL/6J miRNA qRT-PCR 2022 Differential centrifugation|Filtration|Ultracentrifugation|Centrifugal ultrafiltration|OptiPrep density gradient centrifugation Extracellular vesicles 2794 37309723 Mus musculus Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells Colon cancer cells cl C26 Protein Western blotting|Mass spectrometry 2023 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2795 37309723 Mus musculus Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells T-cell lymphoma cells cl EL4 Protein Western blotting|Mass spectrometry 2023 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2796 34168137 Bos taurus Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Bovine milk ts Raw milk - Fraction 5 Protein Western blotting 2021 Differential centrifugation|OptiPrep density gradient centrifugation|Ultracentrifugation Extracellular vesicles 2797 34168137 Bos taurus Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Bovine milk ts Raw milk - Fraction 6 Protein Western blotting 2021 Differential centrifugation|OptiPrep density gradient centrifugation|Ultracentrifugation Extracellular vesicles 2798 34168137 Bos taurus Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Bovine milk ts Raw milk - Fraction 7 Protein Western blotting 2021 Differential centrifugation|OptiPrep density gradient centrifugation|Ultracentrifugation Extracellular vesicles 2799 34168137 Bos taurus Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Bovine milk ts Raw milk - Fraction 8 Protein Western blotting 2021 Differential centrifugation|OptiPrep density gradient centrifugation|Ultracentrifugation Extracellular vesicles 2800 34168137 Bos taurus Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Bovine milk ts Raw milk - Fraction 9 Protein Western blotting 2021 Differential centrifugation|OptiPrep density gradient centrifugation|Ultracentrifugation Extracellular vesicles 2801 34168137 Bos taurus Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Bovine milk ts Commercial milk - Fraction 5 Protein Western blotting 2021 Differential centrifugation|OptiPrep density gradient centrifugation|Ultracentrifugation Extracellular vesicles 2802 34168137 Bos taurus Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Bovine milk ts Commercial milk - Fraction 6 Protein Western blotting 2021 Differential centrifugation|OptiPrep density gradient centrifugation|Ultracentrifugation Extracellular vesicles 2803 34168137 Bos taurus Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Bovine milk ts Commercial milk - Fraction 7 Protein Western blotting 2021 Differential centrifugation|OptiPrep density gradient centrifugation|Ultracentrifugation Extracellular vesicles 2804 34168137 Bos taurus Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Bovine milk ts Commercial milk - Fraction 8 Protein Western blotting 2021 Differential centrifugation|OptiPrep density gradient centrifugation|Ultracentrifugation Extracellular vesicles 2805 34168137 Bos taurus Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Bovine milk ts Commercial milk - Fraction 9 Protein Western blotting 2021 Differential centrifugation|OptiPrep density gradient centrifugation|Ultracentrifugation Extracellular vesicles 2806 34168137 Bos taurus Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Bovine milk ts Raw milk - Fractions 6-8 pooled Protein Western blotting 2021 Differential centrifugation|OptiPrep density gradient centrifugation|Ultracentrifugation Extracellular vesicles 2807 34168137 Bos taurus Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Bovine milk ts Commercial milk - Fractions 6-8 pooled Protein Western blotting 2021 Differential centrifugation|OptiPrep density gradient centrifugation|Ultracentrifugation Extracellular vesicles 2808 34168137 Homo sapiens Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Colorectal cancer cells cl LIM1215 - Fraction 6 Protein Western blotting 2021 Differential centrifugation|OptiPrep density gradient centrifugation|Ultracentrifugation Extracellular vesicles 2809 34168137 Homo sapiens Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Colorectal cancer cells cl LIM1215 - Fraction 7 Protein Western blotting 2021 Differential centrifugation|OptiPrep density gradient centrifugation|Ultracentrifugation Extracellular vesicles 2810 34168137 Homo sapiens Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Colorectal cancer cells cl LIM1215 - Fraction 8 Protein Western blotting 2021 Differential centrifugation|OptiPrep density gradient centrifugation|Ultracentrifugation Extracellular vesicles 2811 34168137 Homo sapiens Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Colorectal cancer cells cl LIM1215 - Fraction 9 Protein Western blotting 2021 Differential centrifugation|OptiPrep density gradient centrifugation|Ultracentrifugation Extracellular vesicles 2812 34168137 Homo sapiens Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Colorectal cancer cells cl LIM1215 - Fraction 10 Protein Western blotting 2021 Differential centrifugation|OptiPrep density gradient centrifugation|Ultracentrifugation Extracellular vesicles 2813 34168137 Homo sapiens Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Colorectal cancer cells cl LIM1215 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2814 34168137 Homo sapiens Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Colorectal cancer cells cl LIM1215 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2815 34168137 Bos taurus Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Bovine milk ts Raw milk Protein|mRNA|miRNA|tRNA Western blotting|Mass spectrometry|Small RNA sequencing 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2816 34168137 Bos taurus Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Bovine milk ts Raw milk Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2817 34168137 Bos taurus Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Bovine milk ts Raw milk Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2818 34168137 Bos taurus Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Bovine milk ts Raw milk Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2819 34168137 Bos taurus Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Bovine milk ts Raw milk Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2820 34168137 Homo sapiens Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Colorectal cancer cells cl LIM1215 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2821 34168137 Homo sapiens Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Colorectal cancer cells cl LIM1215 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2822 34168137 Bos taurus Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Bovine milk ts Commercial milk Protein|mRNA|miRNA|tRNA Mass spectrometry|Small RNA sequencing 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2823 34168137 Bos taurus Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Bovine milk ts Commercial milk Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2824 34168137 Bos taurus Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Bovine milk ts Commercial milk-derived EVs - Fraction 4 Protein Western blotting 2021 Differential centrifugation|OptiPrep density gradient centrifugation|Ultracentrifugation Extracellular vesicles 2825 34168137 Bos taurus Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Bovine milk ts Commercial milk-derived EVs - Fraction 5 Protein Western blotting 2021 Differential centrifugation|OptiPrep density gradient centrifugation|Ultracentrifugation Extracellular vesicles 2826 34168137 Bos taurus Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Bovine milk ts Commercial milk-derived EVs - Fraction 6 Protein Western blotting 2021 Differential centrifugation|OptiPrep density gradient centrifugation|Ultracentrifugation Extracellular vesicles 2827 34168137 Bos taurus Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Bovine milk ts Commercial milk-derived EVs - Fraction 7 Protein Western blotting 2021 Differential centrifugation|OptiPrep density gradient centrifugation|Ultracentrifugation Extracellular vesicles 2828 34168137 Bos taurus Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Bovine milk ts Commercial milk-derived EVs - Fraction 8 Protein Western blotting 2021 Differential centrifugation|OptiPrep density gradient centrifugation|Ultracentrifugation Extracellular vesicles 2829 35058437 Homo sapiens Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2 Plasma ts Sero-negative control Protein Microflow vesiclometry 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2830 35058437 Homo sapiens Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2 Plasma ts COVID-19 patients - Acute phase Protein Microflow vesiclometry 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2831 35058437 Homo sapiens Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2 Plasma ts COVID-19 patients - Convalescent phase Protein Microflow vesiclometry 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2832 35058437 Homo sapiens Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2 Plasma ts COVID-19 inpatients - Convalescent phase Protein Microflow vesiclometry 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2833 35058437 Homo sapiens Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2 Plasma ts COVID-19 outpatients - Convalescent phase Protein Microflow vesiclometry 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2834 35058437 Homo sapiens Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2 Lung cancer cells cl A549 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2835 35058437 Homo sapiens Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2 Lung cancer cells cl A549 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2836 35058437 Homo sapiens Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2 Embryonic kidney cells cl HEK293 Protein Western blotting|Immuno-EM 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2837 35058437 Homo sapiens Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2 Embryonic kidney cells cl HEK293 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2838 35058437 Homo sapiens Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2 Embryonic kidney cells cl HEK293 Protein Western blotting|Immuno-EM|ELISA|Mass spectrometry 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2839 35058437 Homo sapiens Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2 Embryonic kidney cells cl HEK293 Protein Western blotting|Mass spectrometry 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2840 35058437 Homo sapiens Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2 Cervical cancer cells cl HeLa Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2841 35058437 Homo sapiens Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2 Cervical cancer cells cl HeLa Protein Western blotting|ELISA 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2842 35058437 Homo sapiens Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2 Embryonic kidney cells cl HEK293 - Fraction 1 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation|OptiPrep density gradient centrifugation Extracellular vesicles 2843 35058437 Homo sapiens Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2 Embryonic kidney cells cl HEK293 - Fraction 2 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation|OptiPrep density gradient centrifugation Extracellular vesicles 2844 35058437 Homo sapiens Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2 Embryonic kidney cells cl HEK293 - Fraction 3 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation|OptiPrep density gradient centrifugation Extracellular vesicles 2845 35058437 Homo sapiens Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2 Embryonic kidney cells cl HEK293 - Fraction 4 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation|OptiPrep density gradient centrifugation Extracellular vesicles 2846 35058437 Homo sapiens Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2 Embryonic kidney cells cl HEK293 - Fraction 5 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation|OptiPrep density gradient centrifugation Extracellular vesicles 2847 35058437 Homo sapiens Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2 Embryonic kidney cells cl HEK293 - Fraction 6 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation|OptiPrep density gradient centrifugation Extracellular vesicles 2848 35058437 Homo sapiens Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2 Plasma ts NWL-001 - Lung cancer patient Protein Western blotting|Mass spectrometry 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2849 35058437 Homo sapiens Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2 Plasma ts NWL-004 - Lung cancer patient Protein Mass spectrometry 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2850 35058437 Homo sapiens Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2 Plasma ts CSB-012 - COVID-19 patient - convalescent phase Protein Western blotting|Mass spectrometry 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2851 35058437 Homo sapiens Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2 Plasma ts CSB-024 - COVID-19 patient - convalescent phase Protein Mass spectrometry 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2852 33579909 Homo sapiens Sulfisoxazole does not inhibit the secretion of small extracellular vesicles Breast cancer cells cl MDA-MB-231 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2853 33579909 Homo sapiens Sulfisoxazole does not inhibit the secretion of small extracellular vesicles Breast cancer cells cl MDA-MB-231 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2854 33579909 Homo sapiens Sulfisoxazole does not inhibit the secretion of small extracellular vesicles Breast cancer cells cl MDA-MB-231 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2855 33579909 Homo sapiens Sulfisoxazole does not inhibit the secretion of small extracellular vesicles Breast cancer cells cl MDA-MB-231 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2856 33579909 Homo sapiens Sulfisoxazole does not inhibit the secretion of small extracellular vesicles Breast cancer cells cl MDA-MB-231 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2857 33579909 Mus musculus Sulfisoxazole does not inhibit the secretion of small extracellular vesicles Breast cancer cells cl 4T1 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2858 33579909 Mus musculus Sulfisoxazole does not inhibit the secretion of small extracellular vesicles Breast cancer cells cl 4T1 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2859 33579909 Mus musculus Sulfisoxazole does not inhibit the secretion of small extracellular vesicles Breast cancer cells cl 4T1 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2860 33579909 Mus musculus Sulfisoxazole does not inhibit the secretion of small extracellular vesicles Breast cancer cells cl 4T1 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2861 33579909 Mus musculus Sulfisoxazole does not inhibit the secretion of small extracellular vesicles Breast cancer cells cl 4T1 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 2862 30918259 Homo sapiens Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Mammary epithelial cells cl MCF10A Protein Western blotting 2019 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2863 30918259 Homo sapiens Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Breast cancer cells cl MCF7 Protein Western blotting 2019 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2864 30918259 Homo sapiens Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Breast cancer cells cl MDA-MB-231 Protein Western blotting 2019 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2865 30918259 Homo sapiens Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Melanoma cells cl SK-MEL-28 Protein Western blotting 2019 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2866 30918259 Homo sapiens Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Embryonic kidney cells cl HEK293T Protein Western blotting 2019 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2867 30918259 Homo sapiens Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Breast cancer cells cl MDA-MB-231 Protein Western blotting|Mass spectrometry 2019 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2868 30918259 Homo sapiens Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Breast cancer cells cl MDA-MB-231 Protein Western blotting 2019 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2869 30918259 Homo sapiens Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Breast cancer cells cl MDA-MB-231 Protein Western blotting 2019 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2870 30918259 Homo sapiens Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Breast cancer cells cl MDA-MB-231 Protein Western blotting|Mass spectrometry 2019 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2871 30918259 Homo sapiens Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Breast cancer cells cl MDA-MB-231 miRNA miRNA array 2019 Differential centrifugation|Filtration|ExoQuick Kit Small extracellular vesicles 2872 30918259 Homo sapiens Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Breast cancer cells cl MDA-MB-231 miRNA miRNA array 2019 Differential centrifugation|Filtration|ExoQuick Kit Small extracellular vesicles 2873 30918259 Homo sapiens Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Breast cancer cells cl MCF7 Protein Western blotting 2019 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2874 30918259 Homo sapiens Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Breast cancer cells cl MCF7 Protein Western blotting 2019 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2875 30918259 Homo sapiens Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Breast cancer cells cl MCF7 Protein Western blotting 2019 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2876 30918259 Homo sapiens Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Breast cancer cells cl MCF7 Protein Western blotting 2019 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2877 30918259 Homo sapiens Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Melanoma cells cl SK-MEL-28 Protein Western blotting 2019 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2878 30918259 Homo sapiens Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Melanoma cells cl SK-MEL-28 Protein Western blotting 2019 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2879 30918259 Homo sapiens Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Melanoma cells cl SK-MEL-28 Protein Western blotting 2019 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2880 30918259 Homo sapiens Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Melanoma cells cl SK-MEL-28 Protein Western blotting 2019 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2881 30918259 Homo sapiens Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Serum cl|ts BALB/c implanted with MDA-MB-231-luci (+) Protein Western blotting 2019 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2882 30918259 Homo sapiens Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Serum cl|ts BALB/c implanted with MDA-MB-231-luci (+) Protein Western blotting 2019 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2883 30918259 Homo sapiens Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Serum cl|ts BALB/c implanted with MDA-MB-231-luci (+) Protein Western blotting 2019 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2884 30918259 Homo sapiens Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Serum cl|ts BALB/c implanted with MDA-MB-231-luci (+) Protein Western blotting 2019 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2885 30918259 Homo sapiens Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Breast cancer cells cl|ts BALB/c implanted with MDA-MB-231-luci (+) Protein Western blotting 2019 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2886 30918259 Homo sapiens Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Breast cancer cells cl MDA-MB-231-luci (+) Protein Western blotting 2019 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2887 30918259 Mus musculus Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Breast cancer cells cl 4T1-luci (+) Protein Western blotting 2019 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2888 30918259 Homo sapiens Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Breast cancer cells cl|ts BALB/c implanted with MDA-MB-231-WT Protein Western blotting 2019 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2889 30918259 Homo sapiens Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Breast cancer cells cl|ts BALB/c implanted with MDA-MB-231-ETA KD Protein Western blotting 2019 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 2890 28928431 Mus musculus Tumor induces muscle wasting in mice through releasing extracellular Hsp70 and Hsp90 Lung cancer cells cl LLC Protein Western blotting 2017 Centrifugal ultrafiltration|ExoQuick Kit Extracellular vesicles 2891 28928431 Mus musculus Tumor induces muscle wasting in mice through releasing extracellular Hsp70 and Hsp90 Lung cancer cells cl LLC - immunoprecipitation IgG control supernatant Protein Western blotting 2017 Centrifugal ultrafiltration|ExoQuick Kit Extracellular vesicles 2892 28928431 Mus musculus Tumor induces muscle wasting in mice through releasing extracellular Hsp70 and Hsp90 Lung cancer cells cl LLC - immunoprecipitation of CD9 precipitated pellet Protein Western blotting 2017 Centrifugal ultrafiltration|ExoQuick Kit Extracellular vesicles 2893 33732415 Homo sapiens Extracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl-2/caspase-3 pathway Esophageal cancer cells cl YES2 Protein Western blotting 2021 Filtration|Centrifugal ultrafiltration|ExoQuick Kit|Differential centrifugation|Ultracentrifugation Extracellular vesicles 2894 33732415 Homo sapiens Extracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl-2/caspase-3 pathway Esophageal cancer cells cl KYSE30 Protein Western blotting 2021 Filtration|Centrifugal ultrafiltration|ExoQuick Kit|Differential centrifugation|Ultracentrifugation Extracellular vesicles 2895 33732415 Homo sapiens Extracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl-2/caspase-3 pathway Esophageal cancer cells cl KYSE150 Protein Western blotting 2021 Filtration|Centrifugal ultrafiltration|ExoQuick Kit|Differential centrifugation|Ultracentrifugation Extracellular vesicles 2896 33732415 Homo sapiens Extracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl-2/caspase-3 pathway Esophageal cancer cells cl KYSE180 Protein Western blotting 2021 Filtration|Centrifugal ultrafiltration|ExoQuick Kit|Differential centrifugation|Ultracentrifugation Extracellular vesicles 2897 33732415 Homo sapiens Extracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl-2/caspase-3 pathway Esophageal cancer cells cl KYSE70 Protein Western blotting 2021 Filtration|Centrifugal ultrafiltration|ExoQuick Kit|Differential centrifugation|Ultracentrifugation Extracellular vesicles 2898 33732415 Homo sapiens Extracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl-2/caspase-3 pathway Esophageal cancer cells cl KYSE140 Protein Western blotting 2021 Filtration|Centrifugal ultrafiltration|ExoQuick Kit|Differential centrifugation|Ultracentrifugation Extracellular vesicles 2899 33732415 Homo sapiens Extracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl-2/caspase-3 pathway Esophageal cancer cells cl COLO680N Protein Western blotting 2021 Filtration|Centrifugal ultrafiltration|ExoQuick Kit|Differential centrifugation|Ultracentrifugation Extracellular vesicles 2900 33732415 Homo sapiens Extracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl-2/caspase-3 pathway Gastric cancer cells cl AGS Protein Western blotting 2021 Filtration|Centrifugal ultrafiltration|ExoQuick Kit|Differential centrifugation|Ultracentrifugation Extracellular vesicles 2901 33732415 Homo sapiens Extracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl-2/caspase-3 pathway Pancreatic cancer cells cl AsPC1 Protein Western blotting 2021 Filtration|Centrifugal ultrafiltration|ExoQuick Kit|Differential centrifugation|Ultracentrifugation Extracellular vesicles 2902 33732415 Homo sapiens Extracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl-2/caspase-3 pathway Pancreatic cancer cells cl BxPC3 Protein Western blotting 2021 Filtration|Centrifugal ultrafiltration|ExoQuick Kit|Differential centrifugation|Ultracentrifugation Extracellular vesicles 2903 33732415 Mus musculus Extracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl-2/caspase-3 pathway Lung cancer cells cl LLC Protein Western blotting 2021 Filtration|Centrifugal ultrafiltration|ExoQuick Kit|Differential centrifugation|Ultracentrifugation Extracellular vesicles 2904 33732415 Homo sapiens Extracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl-2/caspase-3 pathway Esophageal cancer cells cl KYSE150 Protein Western blotting 2021 Filtration|Centrifugal ultrafiltration|ExoQuick Kit|Differential centrifugation|Ultracentrifugation Extracellular vesicles 2905 33732415 Homo sapiens Extracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl-2/caspase-3 pathway Esophageal cancer cells cl KYSE150 Protein Western blotting 2021 Filtration|Centrifugal ultrafiltration|ExoQuick Kit|Differential centrifugation|Ultracentrifugation Extracellular vesicles 2906 33732415 Homo sapiens Extracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl-2/caspase-3 pathway Esophageal cancer cells cl YES2 Protein Western blotting 2021 Filtration|Centrifugal ultrafiltration|ExoQuick Kit|Differential centrifugation|Ultracentrifugation Extracellular vesicles 2907 33732415 Homo sapiens Extracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl-2/caspase-3 pathway Esophageal cancer cells cl YES2 Protein Western blotting 2021 Filtration|Centrifugal ultrafiltration|ExoQuick Kit|Differential centrifugation|Ultracentrifugation Extracellular vesicles 2908 33732415 Mus musculus Extracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl-2/caspase-3 pathway Lung cancer cells cl LLC Protein Western blotting 2021 Filtration|Centrifugal ultrafiltration|ExoQuick Kit|Differential centrifugation|Ultracentrifugation Extracellular vesicles 2909 33732415 Mus musculus Extracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl-2/caspase-3 pathway Lung cancer cells cl LLC Protein Western blotting 2021 Filtration|Centrifugal ultrafiltration|ExoQuick Kit|Differential centrifugation|Ultracentrifugation Extracellular vesicles 2910 26061593 Homo sapiens Pathogenesis of pancreatic cancer exosome-induced lipolysis in adipose tissue Pancreatic cancer cells cl 6741-1 (MCPAN014) Protein Western blotting 2017 Differential centrifugation|Ultracentrifugation Exosomes 2911 26061593 Homo sapiens Pathogenesis of pancreatic cancer exosome-induced lipolysis in adipose tissue Pancreatic cancer cells cl PANC-1 Protein Western blotting 2017 Differential centrifugation|Ultracentrifugation Exosomes 2912 26061593 Homo sapiens Pathogenesis of pancreatic cancer exosome-induced lipolysis in adipose tissue Plasma ts Non-pancreatic cancer control Protein Western blotting 2017 Differential centrifugation|Ultracentrifugation Exosomes 2913 26061593 Homo sapiens Pathogenesis of pancreatic cancer exosome-induced lipolysis in adipose tissue Plasma ts Pancreatic cancer patients Protein Western blotting 2017 Differential centrifugation|Ultracentrifugation Exosomes 2914 26061593 Homo sapiens Pathogenesis of pancreatic cancer exosome-induced lipolysis in adipose tissue Pancreatic cancer cells cl PANC-1 - Adrenomedullin immunoprecipitation Protein Western blotting 2017 Differential centrifugation|Ultracentrifugation Exosomes 2915 26061593 Homo sapiens Pathogenesis of pancreatic cancer exosome-induced lipolysis in adipose tissue Pancreatic cancer cells cl PANC-1 - Adrenomedullin immunoprecipitation Protein Western blotting 2017 Differential centrifugation|Ultracentrifugation Exosomes 2916 26061593 Homo sapiens Pathogenesis of pancreatic cancer exosome-induced lipolysis in adipose tissue Pancreatic cancer cells cl 6741-1 (MCPAN014) - Adrenomedullin immunoprecipitation Protein Western blotting 2017 Differential centrifugation|Ultracentrifugation Exosomes 2917 26061593 Homo sapiens Pathogenesis of pancreatic cancer exosome-induced lipolysis in adipose tissue Pancreatic cancer cells cl 6741-1 (MCPAN014) - Adrenomedullin immunoprecipitation Protein Western blotting 2017 Differential centrifugation|Ultracentrifugation Exosomes 2918 33661579 Homo sapiens Pannexin-1 channel regulates nuclear content packaging into apoptotic bodies and their size T lymphoblast cl Jurkat T cells Protein Western blotting|Mass spectrometry 2021 Differential centrifugation Apoptotic bodies 2919 33661579 Homo sapiens Pannexin-1 channel regulates nuclear content packaging into apoptotic bodies and their size T lymphoblast cl Jurkat T cells Protein Western blotting|Mass spectrometry 2021 Differential centrifugation Apoptotic bodies 2920 33661579 Homo sapiens Pannexin-1 channel regulates nuclear content packaging into apoptotic bodies and their size T lymphoblast cl Jurkat T cells Protein Western blotting|Mass spectrometry 2021 Differential centrifugation Apoptotic bodies 2921 33661579 Homo sapiens Pannexin-1 channel regulates nuclear content packaging into apoptotic bodies and their size T lymphoblast cl Jurkat T cells Protein Western blotting 2021 Differential centrifugation Apoptotic bodies 2922 33661579 Homo sapiens Pannexin-1 channel regulates nuclear content packaging into apoptotic bodies and their size T lymphoblast cl Jurkat T cells Protein Western blotting 2021 Differential centrifugation Apoptotic bodies 2923 35106941 Homo sapiens K-29 linked ubiquitination of Arrdc4 regulates its function in extracellular vesicle biogenesis Human embryonic kidney cells cl HEK293T Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2924 35106941 Homo sapiens K-29 linked ubiquitination of Arrdc4 regulates its function in extracellular vesicle biogenesis Human embryonic kidney cells cl HEK293T Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2925 35106941 Homo sapiens K-29 linked ubiquitination of Arrdc4 regulates its function in extracellular vesicle biogenesis Human embryonic kidney cells cl HEK293T Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2926 35106941 Homo sapiens K-29 linked ubiquitination of Arrdc4 regulates its function in extracellular vesicle biogenesis Human embryonic kidney cells cl HEK293T Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2927 35106941 Homo sapiens K-29 linked ubiquitination of Arrdc4 regulates its function in extracellular vesicle biogenesis Human embryonic kidney cells cl HEK293T Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2928 35106941 Homo sapiens K-29 linked ubiquitination of Arrdc4 regulates its function in extracellular vesicle biogenesis Human embryonic kidney cells cl HEK293T Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2929 35106941 Homo sapiens K-29 linked ubiquitination of Arrdc4 regulates its function in extracellular vesicle biogenesis Human embryonic kidney cells cl HEK293T Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2930 35106941 Homo sapiens K-29 linked ubiquitination of Arrdc4 regulates its function in extracellular vesicle biogenesis Human embryonic kidney cells cl HEK293T Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2931 35106941 Homo sapiens K-29 linked ubiquitination of Arrdc4 regulates its function in extracellular vesicle biogenesis Human embryonic kidney cells cl HEK293T Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2932 35106941 Homo sapiens K-29 linked ubiquitination of Arrdc4 regulates its function in extracellular vesicle biogenesis Human embryonic kidney cells cl HEK293T Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2933 35106941 Homo sapiens K-29 linked ubiquitination of Arrdc4 regulates its function in extracellular vesicle biogenesis Human embryonic kidney cells cl HEK293T Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2934 35106941 Homo sapiens K-29 linked ubiquitination of Arrdc4 regulates its function in extracellular vesicle biogenesis Human embryonic kidney cells cl HEK293T Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2935 35106941 Homo sapiens K-29 linked ubiquitination of Arrdc4 regulates its function in extracellular vesicle biogenesis Human embryonic kidney cells cl HEK293T Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2936 35106941 Homo sapiens K-29 linked ubiquitination of Arrdc4 regulates its function in extracellular vesicle biogenesis Human embryonic kidney cells cl HEK293T Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2937 35106941 Homo sapiens K-29 linked ubiquitination of Arrdc4 regulates its function in extracellular vesicle biogenesis Human embryonic kidney cells cl HEK293T Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2938 35106941 Homo sapiens K-29 linked ubiquitination of Arrdc4 regulates its function in extracellular vesicle biogenesis Human embryonic kidney cells cl HEK293T Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2939 35106941 Homo sapiens K-29 linked ubiquitination of Arrdc4 regulates its function in extracellular vesicle biogenesis Human embryonic kidney cells cl HEK293T Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2940 35106941 Homo sapiens K-29 linked ubiquitination of Arrdc4 regulates its function in extracellular vesicle biogenesis Human embryonic kidney cells cl HEK293T Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2941 35106941 Cricetulus griseus K-29 linked ubiquitination of Arrdc4 regulates its function in extracellular vesicle biogenesis Ovarian epithelial cells cl CHO Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2942 35106941 Cricetulus griseus K-29 linked ubiquitination of Arrdc4 regulates its function in extracellular vesicle biogenesis Ovarian epithelial cells cl CHO Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2943 35106941 Cricetulus griseus K-29 linked ubiquitination of Arrdc4 regulates its function in extracellular vesicle biogenesis Ovarian epithelial cells cl CHO Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2944 35106941 Cricetulus griseus K-29 linked ubiquitination of Arrdc4 regulates its function in extracellular vesicle biogenesis Ovarian epithelial cells cl CHO Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2945 35106941 Cricetulus griseus K-29 linked ubiquitination of Arrdc4 regulates its function in extracellular vesicle biogenesis Ovarian epithelial cells cl CHO Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2946 35106941 Cricetulus griseus K-29 linked ubiquitination of Arrdc4 regulates its function in extracellular vesicle biogenesis Ovarian epithelial cells cl CHO Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2947 35106941 Cricetulus griseus K-29 linked ubiquitination of Arrdc4 regulates its function in extracellular vesicle biogenesis Ovarian epithelial cells cl CHO Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2948 31101910 Homo sapiens Analysis of extracellular vesicles generated from monocytes under conditions of lytic cell death Monocytes cl THP-1 - Control - 2k pellet Protein Western blotting 2019 Differential centrifugation Extracellular vesicles 2949 31101910 Homo sapiens Analysis of extracellular vesicles generated from monocytes under conditions of lytic cell death Monocytes cl THP-1 - Control - 2k pellet Protein Western blotting 2019 Differential centrifugation Extracellular vesicles 2950 31101910 Homo sapiens Analysis of extracellular vesicles generated from monocytes under conditions of lytic cell death Monocytes cl THP-1 - Primary necrosis - 2k pellet Protein Western blotting 2019 Differential centrifugation Extracellular vesicles 2951 31101910 Homo sapiens Analysis of extracellular vesicles generated from monocytes under conditions of lytic cell death Monocytes cl THP-1 - Secondary necrosis - 2k pellet Protein Western blotting 2019 Differential centrifugation Extracellular vesicles 2952 31101910 Homo sapiens Analysis of extracellular vesicles generated from monocytes under conditions of lytic cell death Monocytes cl THP-1 - Pyroptosis - 2k pellet Protein Western blotting 2019 Differential centrifugation Extracellular vesicles 2953 31101910 Homo sapiens Analysis of extracellular vesicles generated from monocytes under conditions of lytic cell death Monocytes cl THP-1 - Apoptosis - 2k pellet Protein Western blotting 2019 Differential centrifugation Extracellular vesicles 2954 31101910 Homo sapiens Analysis of extracellular vesicles generated from monocytes under conditions of lytic cell death Monocytes cl THP-1 - control - 16k pellet Protein Western blotting 2019 Differential centrifugation Extracellular vesicles 2955 31101910 Homo sapiens Analysis of extracellular vesicles generated from monocytes under conditions of lytic cell death Monocytes cl THP-1 - control - 16k pellet Protein Western blotting 2019 Differential centrifugation Extracellular vesicles 2956 31101910 Homo sapiens Analysis of extracellular vesicles generated from monocytes under conditions of lytic cell death Monocytes cl THP-1 - Primary necrosis - 16k pellet Protein Western blotting 2019 Differential centrifugation Extracellular vesicles 2957 31101910 Homo sapiens Analysis of extracellular vesicles generated from monocytes under conditions of lytic cell death Monocytes cl THP-1 - Secondary necrosis - 16k pellet Protein Western blotting 2019 Differential centrifugation Extracellular vesicles 2958 31101910 Homo sapiens Analysis of extracellular vesicles generated from monocytes under conditions of lytic cell death Monocytes cl THP-1 - Pyroptosis - 16k pellet Protein Western blotting 2019 Differential centrifugation Extracellular vesicles 2959 31101910 Homo sapiens Analysis of extracellular vesicles generated from monocytes under conditions of lytic cell death Monocytes cl THP-1 - Apoptosis - 16k pellet Protein Western blotting 2019 Differential centrifugation Extracellular vesicles 2960 31101910 Homo sapiens Analysis of extracellular vesicles generated from monocytes under conditions of lytic cell death Monocytes cl THP-1 - control - 100k pellet Protein Western blotting 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2961 31101910 Homo sapiens Analysis of extracellular vesicles generated from monocytes under conditions of lytic cell death Monocytes cl THP-1 - control - 100k pellet Protein Western blotting 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2962 31101910 Homo sapiens Analysis of extracellular vesicles generated from monocytes under conditions of lytic cell death Monocytes cl THP-1 - Primary necrosis - 100k pellet Protein Western blotting 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2963 31101910 Homo sapiens Analysis of extracellular vesicles generated from monocytes under conditions of lytic cell death Monocytes cl THP-1 - Secondary necrosis - 100k pellet Protein Western blotting 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2964 31101910 Homo sapiens Analysis of extracellular vesicles generated from monocytes under conditions of lytic cell death Monocytes cl THP-1 - Pyroptosis - 100k pellet Protein Western blotting 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2965 31101910 Homo sapiens Analysis of extracellular vesicles generated from monocytes under conditions of lytic cell death Monocytes cl THP-1 - Apoptosis - 100k pellet Protein Western blotting 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 2966 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Melanoma cells cl A375 Protein Western blotting|Reverse phase protein array 2018 Differential centrifugation|Ultracentrifugation Exosomes 2967 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Melanoma cells cl UACC-903 Protein Western blotting|Reverse phase protein array 2018 Differential centrifugation|Ultracentrifugation Exosomes 2968 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Melanoma cells cl WM9 Protein Western blotting|Reverse phase protein array|Immuno-EM|ELISA 2018 Differential centrifugation|Ultracentrifugation Exosomes 2969 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Melanoma cells cl WM164 Protein Western blotting|Reverse phase protein array|ELISA 2018 Differential centrifugation|Ultracentrifugation Exosomes 2970 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Melanoma cells cl WM1552C Protein Reverse phase protein array 2018 Differential centrifugation|Ultracentrifugation Exosomes 2971 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Melanoma cells cl WM35 Protein Reverse phase protein array 2018 Differential centrifugation|Ultracentrifugation Exosomes 2972 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Melanoma cells cl WM793 Protein Reverse phase protein array 2018 Differential centrifugation|Ultracentrifugation Exosomes 2973 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Melanoma cells cl WM902B Protein Reverse phase protein array 2018 Differential centrifugation|Ultracentrifugation Exosomes 2974 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Melanoma cells cl WM9 - Fraction 6 Protein Western blotting 2018 Differential centrifugation|Iodixanol density gradient centrifugation|Ultracentrifugation Exosomes 2975 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Melanoma cells cl WM9 - Fraction 7 Protein Western blotting 2018 Differential centrifugation|Iodixanol density gradient centrifugation|Ultracentrifugation Exosomes 2976 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Melanoma cells cl WM9 - Fraction 8 Protein Western blotting 2018 Differential centrifugation|Iodixanol density gradient centrifugation|Ultracentrifugation Exosomes 2977 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Melanoma cells cl WM9 - Fraction 9 Protein Western blotting 2018 Differential centrifugation|Iodixanol density gradient centrifugation|Ultracentrifugation Exosomes 2978 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Melanoma cells cl WM9 - Fraction 10 Protein Western blotting 2018 Differential centrifugation|Iodixanol density gradient centrifugation|Ultracentrifugation Exosomes 2979 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Melanoma cells cl WM9 - 16.5k pellet Protein Western blotting|ELISA 2018 Differential centrifugation Microvesicles 2980 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Melanoma cells cl WM164 - 16.5k pellet Protein Western blotting|ELISA 2018 Differential centrifugation Microvesicles 2981 30089911 Mus musculus Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Melanoma cells cl B16-F10 Protein Western blotting 2018 Differential centrifugation|Ultracentrifugation Exosomes 2982 30089911 Mus musculus Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Melanoma cells cl B16-F10 - 16.5k pellet Protein Western blotting 2018 Differential centrifugation Microvesicles 2983 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Melanoma cells cl WM9 Protein Western blotting|ELISA 2018 Differential centrifugation|Ultracentrifugation Exosomes 2984 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Melanoma cells cl WM164 Protein Western blotting|ELISA 2018 Differential centrifugation|Ultracentrifugation Exosomes 2985 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Melanoma cells cl WM9 Protein Western blotting 2018 Differential centrifugation|Ultracentrifugation Exosomes 2986 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Melanoma cells cl WM9 Protein Western blotting 2018 Differential centrifugation|Ultracentrifugation Exosomes 2987 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Melanoma cells cl WM9 Protein Western blotting 2018 Differential centrifugation|Ultracentrifugation Exosomes 2988 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Melanoma cells cl WM9 Protein Western blotting 2018 Differential centrifugation|Ultracentrifugation Exosomes 2989 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Melanoma cells cl WM9 Protein Western blotting 2018 Differential centrifugation|Ultracentrifugation Exosomes 2990 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Melanoma cells cl WM9 Protein Western blotting 2018 Differential centrifugation|Ultracentrifugation Exosomes 2991 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Plasma ts Healthy donors Protein Western blotting|ELISA 2018 Differential centrifugation|Ultracentrifugation Exosomes 2992 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Plasma ts Melanoma stage IV patients Protein Western blotting|ELISA 2018 Differential centrifugation|Ultracentrifugation Exosomes 2993 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Plasma ts Healthy donors - 16.5k pellet Protein ELISA 2018 Differential centrifugation|Ultracentrifugation Microvesicles 2994 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Plasma ts Melanoma stage IV patients - 16.5k pellet Protein Western blotting|ELISA 2018 Differential centrifugation Microvesicles 2995 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Plasma ts Melanoma stage IV patients - Fraction 7 Protein Western blotting 2018 Differential centrifugation|Ultracentrifugation Exosomes 2996 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Plasma ts Melanoma stage IV patients - Fraction 8 Protein Western blotting 2018 Differential centrifugation|Ultracentrifugation Exosomes 2997 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Plasma ts Melanoma stage IV patients - Fraction 9 Protein Western blotting 2018 Differential centrifugation|Ultracentrifugation Exosomes 2998 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Plasma ts Melanoma stage IV patients - Fraction 10 Protein Western blotting 2018 Differential centrifugation|Ultracentrifugation Exosomes 2999 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Plasma cl|ts Athymic nude mice implanted with WM9 Protein ELISA 2018 Differential centrifugation|Ultracentrifugation Exosomes 3000 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Melanoma cells cl MEL624 Protein Western blotting 2018 Differential centrifugation|Ultracentrifugation Exosomes 3001 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Melanoma cells cl MEL624 Protein Reverse phase protein array|Western blotting|ELISA 2018 Differential centrifugation|Ultracentrifugation Exosomes 3002 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Lung cancer cells cl H1299 Protein Western blotting 2018 Differential centrifugation|Ultracentrifugation Exosomes 3003 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Lung cancer cells cl H1299 - 16.5k pellet Protein Western blotting 2018 Differential centrifugation Microvesicles 3004 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Lung cancer cells cl H358 Protein Western blotting 2018 Differential centrifugation|Ultracentrifugation Exosomes 3005 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Lung cancer cells cl H358 - 16.5k pellet Protein Western blotting 2018 Differential centrifugation Microvesicles 3006 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Lung cancer cells cl H1264 Protein Western blotting 2018 Differential centrifugation|Ultracentrifugation Exosomes 3007 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Lung cancer cells cl H1264 - 16.5k pellet Protein Western blotting 2018 Differential centrifugation Microvesicles 3008 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Breast cancer cells cl MDA-MB-231 Protein Western blotting 2018 Differential centrifugation|Ultracentrifugation Exosomes 3009 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Breast cancer cells cl MDA-MB-231 - 16.5k pellet Protein Western blotting 2018 Differential centrifugation Microvesicles 3010 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Breast cancer cells cl MDA-MB-231 Protein Western blotting 2018 Differential centrifugation|Ultracentrifugation Exosomes 3011 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Lung cancer cells cl H1299 Protein Western blotting 2018 Differential centrifugation|Ultracentrifugation Exosomes 3012 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Lung cancer cells cl H358 Protein Western blotting 2018 Differential centrifugation|Ultracentrifugation Exosomes 3013 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Lung cancer cells cl H1264 Protein Western blotting 2018 Differential centrifugation|Ultracentrifugation Exosomes 3014 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Plasma ts Melanoma patient - Pembrolizumab responders Protein ELISA 2018 Differential centrifugation|Ultracentrifugation Exosomes 3015 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Plasma ts Melanoma patient - Pembrolizumab non-responders Protein ELISA 2018 Differential centrifugation|Ultracentrifugation Exosomes 3016 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Plasma ts Melanoma patients - Pembrolizumab responders - 16.5k pellet Protein ELISA 2018 Differential centrifugation Microvesicles 3017 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Plasma ts Melanoma patients - Pembrolizumab non-responders - 16.5k pellet Protein ELISA 2018 Differential centrifugation Microvesicles 3018 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Plasma ts Melanoma patient Protein ELISA 2018 Differential centrifugation|Ultracentrifugation Exosomes 3019 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Plasma ts Melanoma patients Protein ELISA 2018 Differential centrifugation|Ultracentrifugation Exosomes 3020 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Plasma ts Melanoma patients Protein ELISA 2018 Differential centrifugation|Ultracentrifugation Exosomes 3021 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Plasma ts Melanoma patients Protein ELISA 2018 Differential centrifugation|Ultracentrifugation Exosomes 3022 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Plasma ts Melanoma patients Protein ELISA 2018 Differential centrifugation|Ultracentrifugation Exosomes 3023 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Plasma ts Melanoma patients - 16.5k pellet Protein ELISA 2018 Differential centrifugation Microvesicles 3024 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Plasma ts Melanoma patients - 16.5k pellet Protein ELISA 2018 Differential centrifugation Microvesicles 3025 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Plasma ts Melanoma patients - 16.5k pellet Protein ELISA 2018 Differential centrifugation Microvesicles 3026 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Plasma ts Melanoma patients - 16.5k pellet Protein ELISA 2018 Differential centrifugation Microvesicles 3027 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Plasma ts Melanoma patients - 16.5k pellet Protein ELISA 2018 Differential centrifugation Microvesicles 3028 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Plasma ts Melanoma patients - Pembrolizumab responders Protein ELISA 2018 Differential centrifugation|Ultracentrifugation Exosomes 3029 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Plasma ts Melanoma patients - Pembrolizumab responders Protein ELISA 2018 Differential centrifugation|Ultracentrifugation Exosomes 3030 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Plasma ts Melanoma patients - Pembrolizumab responders Protein ELISA 2018 Differential centrifugation|Ultracentrifugation Exosomes 3031 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Plasma ts Melanoma patients - Pembrolizumab responders Protein ELISA 2018 Differential centrifugation|Ultracentrifugation Exosomes 3032 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Plasma ts Melanoma patients - Pembrolizumab non-responders Protein ELISA 2018 Differential centrifugation|Ultracentrifugation Exosomes 3033 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Plasma ts Melanoma patients - Pembrolizumab non-responders Protein ELISA 2018 Differential centrifugation|Ultracentrifugation Exosomes 3034 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Plasma ts Melanoma patients - Pembrolizumab non-responders Protein ELISA 2018 Differential centrifugation|Ultracentrifugation Exosomes 3035 30089911 Homo sapiens Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Plasma ts Melanoma patients - Pembrolizumab non-responders Protein ELISA 2018 Differential centrifugation|Ultracentrifugation Exosomes 3036 33893753 Homo sapiens Label-free quantitative proteomic analysis of extracellular vesicles released from fibroblasts derived from patients with spinal muscular atrophy Fibroblasts cl GM03813 - SMA type 2 Protein Mass spectrometry 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 3037 33893753 Homo sapiens Label-free quantitative proteomic analysis of extracellular vesicles released from fibroblasts derived from patients with spinal muscular atrophy Fibroblasts cl GM03814 - Normal Protein Mass spectrometry 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 3038 33893753 Homo sapiens Label-free quantitative proteomic analysis of extracellular vesicles released from fibroblasts derived from patients with spinal muscular atrophy Fibroblasts cl GM03813 - SMA type 2 Protein Western blotting 2021 Centrifugation|Polyethylene glycol-based precipitation Extracellular vesicles 3039 33893753 Homo sapiens Label-free quantitative proteomic analysis of extracellular vesicles released from fibroblasts derived from patients with spinal muscular atrophy Fibroblasts cl GM03814 - Normal Protein Western blotting 2021 Centrifugation|Polyethylene glycol-based precipitation Extracellular vesicles 3040 33893753 Homo sapiens Label-free quantitative proteomic analysis of extracellular vesicles released from fibroblasts derived from patients with spinal muscular atrophy Fibroblasts cl AG08498 - Normal Protein Western blotting 2021 Centrifugation|Polyethylene glycol-based precipitation Extracellular vesicles 3041 33893753 Homo sapiens Label-free quantitative proteomic analysis of extracellular vesicles released from fibroblasts derived from patients with spinal muscular atrophy Fibroblasts cl AG07095 - Normal Protein Western blotting 2021 Centrifugation|Polyethylene glycol-based precipitation Extracellular vesicles 3042 33893753 Homo sapiens Label-free quantitative proteomic analysis of extracellular vesicles released from fibroblasts derived from patients with spinal muscular atrophy Fibroblasts cl GM05565 - Normal Protein Western blotting 2021 Centrifugation|Polyethylene glycol-based precipitation Extracellular vesicles 3043 33893753 Homo sapiens Label-free quantitative proteomic analysis of extracellular vesicles released from fibroblasts derived from patients with spinal muscular atrophy Fibroblasts cl GM00232 - SMA type 1 Protein Western blotting 2021 Centrifugation|Polyethylene glycol-based precipitation Extracellular vesicles 3044 33893753 Homo sapiens Label-free quantitative proteomic analysis of extracellular vesicles released from fibroblasts derived from patients with spinal muscular atrophy Fibroblasts cl GM22592 - SMA type 2 Protein Western blotting 2021 Centrifugation|Polyethylene glycol-based precipitation Extracellular vesicles 3045 34294888 Homo sapiens Exosomal miR-101-3p and miR-423-5p inhibit medulloblastoma tumorigenesis through targeting FOXP4 and EZH2 Plasma ts Medulloblastoma patients Protein|miRNA Western blotting|RNA sequencing|RT-qPCR 2022 Differential centrifugation|Ultracentrifugation Exosomes 3046 34294888 Homo sapiens Exosomal miR-101-3p and miR-423-5p inhibit medulloblastoma tumorigenesis through targeting FOXP4 and EZH2 Plasma ts Healthy controls Protein|miRNA Western blotting|RNA sequencing|RT-qPCR 2022 Differential centrifugation|Ultracentrifugation Exosomes 3047 34294888 Homo sapiens Exosomal miR-101-3p and miR-423-5p inhibit medulloblastoma tumorigenesis through targeting FOXP4 and EZH2 Monocytes cl THP-1 miRNA RT-qPCR 2022 Differential centrifugation|Ultracentrifugation Exosomes 3048 34294888 Homo sapiens Exosomal miR-101-3p and miR-423-5p inhibit medulloblastoma tumorigenesis through targeting FOXP4 and EZH2 Glial cells cl HMO6 miRNA RT-qPCR 2022 Differential centrifugation|Ultracentrifugation Exosomes 3049 34294888 Homo sapiens Exosomal miR-101-3p and miR-423-5p inhibit medulloblastoma tumorigenesis through targeting FOXP4 and EZH2 Monocytes ts Peripheral blood-derived CD14+ monocytes - Healthy controls miRNA RT-qPCR 2022 Differential centrifugation|Ultracentrifugation Exosomes 3050 34294888 Homo sapiens Exosomal miR-101-3p and miR-423-5p inhibit medulloblastoma tumorigenesis through targeting FOXP4 and EZH2 Monocytes ts Peripheral bloode-derived CD14+ monocytes - Medulloblastoma patients miRNA RT-qPCR 2022 Differential centrifugation|Ultracentrifugation Exosomes 3051 34294888 Homo sapiens Exosomal miR-101-3p and miR-423-5p inhibit medulloblastoma tumorigenesis through targeting FOXP4 and EZH2 Plasma ts Medulloblastoma (WNT subtype) patients miRNA RT-qPCR 2022 Differential centrifugation|Ultracentrifugation Exosomes 3052 34294888 Homo sapiens Exosomal miR-101-3p and miR-423-5p inhibit medulloblastoma tumorigenesis through targeting FOXP4 and EZH2 Plasma ts Medulloblastoma (SHH subtype) patients miRNA RT-qPCR 2022 Differential centrifugation|Ultracentrifugation Exosomes 3053 34294888 Homo sapiens Exosomal miR-101-3p and miR-423-5p inhibit medulloblastoma tumorigenesis through targeting FOXP4 and EZH2 Plasma ts Medulloblastoma (Group 3 subtype) patients miRNA RT-qPCR 2022 Differential centrifugation|Ultracentrifugation Exosomes 3054 34294888 Homo sapiens Exosomal miR-101-3p and miR-423-5p inhibit medulloblastoma tumorigenesis through targeting FOXP4 and EZH2 Plasma ts Medulloblastoma (Group 4) patients miRNA RT-qPCR 2022 Differential centrifugation|Ultracentrifugation Exosomes 3055 33827783 Mus musculus Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Pancreatic duct epithelial cells cl Primary pancreatic duct epithelial cells Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Exosomes 3056 33827783 Mus musculus Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Pancreatic cancer cells cl Panc02 Protein Western blotting|Immuno-EM 2022 Differential centrifugation|Ultracentrifugation Exosomes 3057 33827783 Mus musculus Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Pancreatic cancer cells cl KPC Protein Western blotting|Immuno-EM 2022 Differential centrifugation|Ultracentrifugation Exosomes 3058 33827783 Mus musculus Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Pancreatic cancer cells cl Panc02 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Exosomes 3059 33827783 Mus musculus Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Pancreatic cancer cells cl KPC Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Exosomes 3060 33827783 Homo sapiens Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Pancreatic duct epithelial cells ts Normal pancreatic tissue Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Exosomes 3061 33827783 Homo sapiens Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Pancreatic cancer cells ts Pancreatic ductal adenocarcinoma tissue with liver metastasis Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Exosomes 3062 33827783 Homo sapiens Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Pancreatic cancer cells ts Pancreatic ductal adenocarcinoma tissue without liver metastasis Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Exosomes 3063 33827783 Homo sapiens Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Serum ts Normal pancreatic tissue Protein Western blotting 2022 Total Exosome isolation Kit Exosomes 3064 33827783 Homo sapiens Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Serum ts Pancreatic ductal adenocarcinoma tissue with liver metastasis Protein Western blotting 2022 Total Exosome isolation Kit Exosomes 3065 33827783 Homo sapiens Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Serum ts Pancreatic ductal adenocarcinoma tissue without liver metastasis Protein Western blotting 2022 Total Exosome isolation Kit Exosomes 3066 33827783 Homo sapiens Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Pancreatic duct epithelial cells ts Normal pancreatic tissue Protein Western blotting|Immuno-EM 2022 Total Exosome isolation Kit Exosomes 3067 33827783 Homo sapiens Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Pancreatic cancer cells ts Pancreatic ductal adenocarcinoma tissue Protein Western blotting|Immuno-EM 2022 Total Exosome isolation Kit Exosomes 3068 33827783 Homo sapiens Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Serum ts Healthy controls Protein Western blotting|Immuno-EM 2022 Total Exosome isolation Kit Exosomes 3069 33827783 Homo sapiens Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Serum ts Pancreatic ductal adenocarcinoma patients Protein Western blotting|Immuno-EM 2022 Total Exosome isolation Kit Exosomes 3070 33827783 Homo sapiens Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Pancreatic cancer cells cl Panc02 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Exosomes 3071 33827783 Homo sapiens Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Pancreatic cancer cells cl Panc02 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Exosomes 3072 33827783 Homo sapiens Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Pancreatic cancer cells cl KPC Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Exosomes 3073 33827783 Homo sapiens Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Pancreatic cancer cells cl KPC Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Exosomes 3074 33827783 Homo sapiens Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Pancreatic cancer cells cl Panc02 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Exosomes 3075 33827783 Homo sapiens Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Pancreatic cancer cells cl Panc02 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Exosomes 3076 33827783 Homo sapiens Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Pancreatic cancer cells cl KPC Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Exosomes 3077 33827783 Homo sapiens Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Pancreatic cancer cells cl KPC Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Exosomes 3078 33827783 Homo sapiens Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Pancreatic cancer cells cl Panc02 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Exosomes 3079 33827783 Homo sapiens Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Pancreatic cancer cells cl Panc02 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Exosomes 3080 33827783 Homo sapiens Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Pancreatic cancer cells cl KPC Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Exosomes 3081 33827783 Homo sapiens Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Pancreatic cancer cells cl KPC Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Exosomes 3082 33827783 Mus musculus Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Pancreatic duct epithelial cells cl Primary pancreatic duct epithelial cells Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Exosomes 3083 33827783 Mus musculus Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment Pancreatic duct epithelial cells cl Primary pancreatic duct epithelial cells Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation Exosomes 3084 35665306 Mus musculus Regulation of aged skeletal muscle regeneration by circulating extracellular vesicles Serum ts Young - C57BL/6 Protein In-cell Western immunofluorescence 2021 Size exclusion chromatography|Ultracentrifugation Extracellular vesicles 3085 35665306 Mus musculus Regulation of aged skeletal muscle regeneration by circulating extracellular vesicles Serum ts Aged (21-24 month old) - C57BL/6 Protein In-cell Western immunofluorescence 2021 Size exclusion chromatography|Ultracentrifugation Extracellular vesicles 3086 36631249 Homo sapiens S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Plasma ts Healthy donors Protein Western blotting 2023 Differential centrifugation|Ultracentrifugation Extracellular vesicles 3087 36631249 Homo sapiens S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Plasma ts Hepatocellular carcinoma patients Protein Western blotting|Immuno-EM 2023 Differential centrifugation|Ultracentrifugation Extracellular vesicles 3088 36631249 Homo sapiens S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Liver cancer cells cl PLC Protein Western blotting 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3089 36631249 Homo sapiens S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Liver cancer cells cl PLC Protein Western blotting 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3090 36631249 Homo sapiens S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Liver cancer cells cl 97L Protein Western blotting 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3091 36631249 Homo sapiens S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Liver cancer cells cl 97L Protein Western blotting 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3092 36631249 Homo sapiens S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Liver cancer cells cl MIHA Protein Western blotting 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3093 36631249 Homo sapiens S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Liver cancer cells cl MIHA Protein Western blotting 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3094 36631249 Homo sapiens S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Liver cancer cells cl 97H Protein Western blotting 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3095 36631249 Homo sapiens S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Liver cancer cells cl 97H Protein Western blotting 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3096 36631249 Homo sapiens S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Liver cancer cells cl 97H Protein Immuno-EM 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3097 36631249 Homo sapiens S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Liver cancer cells cl 97L Protein Immuno-EM 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3098 36631249 Homo sapiens S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Liver cancer cells cl 97H Protein Western blotting 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3099 36631249 Homo sapiens S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Liver cancer cells cl 97H Protein Western blotting 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3100 36631249 Homo sapiens S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Liver cancer cells cl 97H Protein Western blotting 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3101 36631249 Homo sapiens S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Liver cancer cells cl 97H Protein Western blotting 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3102 36631249 Homo sapiens S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Liver cancer cells cl PLC Protein Western blotting 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3103 36631249 Homo sapiens S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Liver cancer cells cl PLC Protein Western blotting 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3104 36631249 Homo sapiens S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Liver cancer cells cl PLC Protein Western blotting 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3105 36631249 Homo sapiens S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos Liver cancer cells cl PLC Protein Western blotting 2023 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3106 30967557 Mus musculus KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a Hippocampal neuronal cells cl HT22 Protein Western blotting 2019 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 3107 30967557 Mus musculus KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a Hippocampal neuronal cells cl HT22 Protein Western blotting 2019 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 3108 30967557 Mus musculus KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a Hippocampal neuronal cells cl HT22 - 10k pellet Protein Western blotting 2019 Differential centrifugation Extracellular vesicles 3109 30967557 Mus musculus KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a Hippocampal neuronal cells cl HT22 - 10k pellet Protein Western blotting 2019 Differential centrifugation Extracellular vesicles 3110 30967557 Mus musculus KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a Hippocampal neuronal cells cl HT22 - 2k pellet Protein Western blotting 2019 Differential centrifugation Extracellular vesicles 3111 30967557 Mus musculus KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a Hippocampal neuronal cells cl HT22 - 2k pellet Protein Western blotting 2019 Differential centrifugation Extracellular vesicles 3112 30967557 Mus musculus KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a Hippocampal neuronal cells cl HT22 Protein Western blotting 2019 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 3113 30967557 Mus musculus KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a Hippocampal neuronal cells cl HT22 Protein Western blotting 2019 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 3114 30967557 Mus musculus KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a Podocytes cl MPC-5 Protein Western blotting 2019 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 3115 30967557 Mus musculus KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a Podocytes cl MPC-5 Protein Western blotting 2019 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 3116 30967557 Mus musculus KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a Brain ts WT mice - Fraction c Protein Western blotting 2019 Differential centrifugation|Filtration|Sucrose density gradient centrifugation|Ultracentrifugation Exosomes 3117 30967557 Mus musculus KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a Brain ts WT mice - Fraction d Protein Western blotting 2019 Differential centrifugation|Filtration|Sucrose density gradient centrifugation|Ultracentrifugation Exosomes 3118 30967557 Mus musculus KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a Brain ts WT mice - Fraction e Protein Western blotting 2019 Differential centrifugation|Filtration|Sucrose density gradient centrifugation|Ultracentrifugation Exosomes 3119 30967557 Mus musculus KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a Kidney cells ts WT mice - Fraction c Protein Western blotting 2019 Differential centrifugation|Filtration|Sucrose density gradient centrifugation|Ultracentrifugation Exosomes 3120 30967557 Mus musculus KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a Kidney cells ts WT mice - Fraction d Protein Western blotting 2019 Differential centrifugation|Filtration|Sucrose density gradient centrifugation|Ultracentrifugation Exosomes 3121 30967557 Mus musculus KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a Kidney cells ts WT mice - Fraction e Protein Western blotting 2019 Differential centrifugation|Filtration|Sucrose density gradient centrifugation|Ultracentrifugation Exosomes 3122 30967557 Mus musculus KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a Brain ts KO mice - Fraction c Protein Western blotting 2019 Differential centrifugation|Filtration|Sucrose density gradient centrifugation|Ultracentrifugation Exosomes 3123 30967557 Mus musculus KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a Brain ts KO mice - Fraction d Protein Western blotting 2019 Differential centrifugation|Filtration|Sucrose density gradient centrifugation|Ultracentrifugation Exosomes 3124 30967557 Mus musculus KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a Kidney cells ts KO mice - Fraction c Protein Western blotting 2019 Differential centrifugation|Filtration|Sucrose density gradient centrifugation|Ultracentrifugation Exosomes 3125 30967557 Mus musculus KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a Kidney cells ts KO mice - Fraction d Protein Western blotting 2019 Differential centrifugation|Filtration|Sucrose density gradient centrifugation|Ultracentrifugation Exosomes 3126 30967557 Mus musculus KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a Kidney cells ts KO mice - Fraction e Protein Western blotting 2019 Differential centrifugation|Filtration|Sucrose density gradient centrifugation|Ultracentrifugation Exosomes 3127 30967557 Mus musculus KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a Hippocampal neuronal cells cl HT22 Protein Western blotting 2019 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 3128 30967557 Mus musculus KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a Hippocampal neuronal cells cl HT22 Protein Western blotting 2019 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 3129 34500436 Homo sapiens MiR-185-5p targets RAB35 gene to regulate tumor cell-derived exosomes-mediated proliferation, migration and invasion of non-small cell lung cancer cells Lung cancer cells cl A549 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Exosomes 3130 34500436 Homo sapiens MiR-185-5p targets RAB35 gene to regulate tumor cell-derived exosomes-mediated proliferation, migration and invasion of non-small cell lung cancer cells Lung cancer cells cl A549 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Exosomes 3131 34500436 Homo sapiens MiR-185-5p targets RAB35 gene to regulate tumor cell-derived exosomes-mediated proliferation, migration and invasion of non-small cell lung cancer cells Lung cancer cells cl A549 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Exosomes 3132 34500436 Homo sapiens MiR-185-5p targets RAB35 gene to regulate tumor cell-derived exosomes-mediated proliferation, migration and invasion of non-small cell lung cancer cells Lung cancer cells cl A549 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Exosomes 3133 34500436 Homo sapiens MiR-185-5p targets RAB35 gene to regulate tumor cell-derived exosomes-mediated proliferation, migration and invasion of non-small cell lung cancer cells Lung cancer cells cl A549 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Exosomes 3134 34500436 Homo sapiens MiR-185-5p targets RAB35 gene to regulate tumor cell-derived exosomes-mediated proliferation, migration and invasion of non-small cell lung cancer cells Lung cancer cells cl H2170 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Exosomes 3135 34500436 Homo sapiens MiR-185-5p targets RAB35 gene to regulate tumor cell-derived exosomes-mediated proliferation, migration and invasion of non-small cell lung cancer cells Lung cancer cells cl H2170 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Exosomes 3136 34500436 Homo sapiens MiR-185-5p targets RAB35 gene to regulate tumor cell-derived exosomes-mediated proliferation, migration and invasion of non-small cell lung cancer cells Lung cancer cells cl H2170 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Exosomes 3137 34500436 Homo sapiens MiR-185-5p targets RAB35 gene to regulate tumor cell-derived exosomes-mediated proliferation, migration and invasion of non-small cell lung cancer cells Lung cancer cells cl H2170 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Exosomes 3138 34500436 Homo sapiens MiR-185-5p targets RAB35 gene to regulate tumor cell-derived exosomes-mediated proliferation, migration and invasion of non-small cell lung cancer cells Lung cancer cells cl H2170 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Exosomes 3139 34497265 Homo sapiens Tumor-derived exosomal miR-3157-3p promotes angiogenesis, vascular permeability and metastasis by targeting TIMP/KLF2 in non-small cell lung cancer Plasma ts Non-small cell lung carcinoma patients Protein|miRNA Western blotting|Microarray 2021 ExoQuick Kit Exosomes 3140 34497265 Homo sapiens Tumor-derived exosomal miR-3157-3p promotes angiogenesis, vascular permeability and metastasis by targeting TIMP/KLF2 in non-small cell lung cancer Plasma ts Healthy controls Protein|miRNA Western blotting|Microarray 2021 ExoQuick Kit Exosomes 3141 34497265 Homo sapiens Tumor-derived exosomal miR-3157-3p promotes angiogenesis, vascular permeability and metastasis by targeting TIMP/KLF2 in non-small cell lung cancer Lung cancer cells ts Non-small cell lung carcinoma tumour explant miRNA qRT-PCR 2021 Differential centrifugation|Ultracentrifugation Exosomes 3142 34497265 Homo sapiens Tumor-derived exosomal miR-3157-3p promotes angiogenesis, vascular permeability and metastasis by targeting TIMP/KLF2 in non-small cell lung cancer Lung epithelial cells ts Healthy lung tissue explant miRNA qRT-PCR 2021 Differential centrifugation|Ultracentrifugation Exosomes 3143 34497265 Homo sapiens Tumor-derived exosomal miR-3157-3p promotes angiogenesis, vascular permeability and metastasis by targeting TIMP/KLF2 in non-small cell lung cancer Plasma ts Healthy controls miRNA qRT-PCR 2021 ExoQuick Kit Exosomes 3144 34497265 Homo sapiens Tumor-derived exosomal miR-3157-3p promotes angiogenesis, vascular permeability and metastasis by targeting TIMP/KLF2 in non-small cell lung cancer Plasma ts Non-small cell lung carcinoma patients with metastasis miRNA qRT-PCR 2021 ExoQuick Kit Exosomes 3145 34497265 Homo sapiens Tumor-derived exosomal miR-3157-3p promotes angiogenesis, vascular permeability and metastasis by targeting TIMP/KLF2 in non-small cell lung cancer Plasma ts Non-small cell lung carcinoma patients without metastasis miRNA qRT-PCR 2021 ExoQuick Kit Exosomes 3146 34497265 Homo sapiens Tumor-derived exosomal miR-3157-3p promotes angiogenesis, vascular permeability and metastasis by targeting TIMP/KLF2 in non-small cell lung cancer Lung cancer cells cl A549 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Exosomes 3147 34497265 Homo sapiens Tumor-derived exosomal miR-3157-3p promotes angiogenesis, vascular permeability and metastasis by targeting TIMP/KLF2 in non-small cell lung cancer Lung cancer cells cl H1299 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Exosomes 3148 29438363 Homo sapiens CD9-positive exosomes from cancer-associated fibroblasts stimulate the migration ability of scirrhous-type gastric cancer cells Fibroblasts cl CaF64 Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 3149 29438363 Homo sapiens CD9-positive exosomes from cancer-associated fibroblasts stimulate the migration ability of scirrhous-type gastric cancer cells Fibroblasts cl CaF65 Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 3150 29438363 Homo sapiens CD9-positive exosomes from cancer-associated fibroblasts stimulate the migration ability of scirrhous-type gastric cancer cells Fibroblasts cl NF65 Protein Western blotting 2018 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 3151 34887361 Mus musculus Endothelial cell-derived exosomal circHIPK3 promotes the proliferation of vascular smooth muscle cells induced by high glucose via the miR-106a-5p/Foxo1/Vcam1 pathway Endothelial cells cl Mouse aortic endothelial cells (MAEC) Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 3152 34887361 Mus musculus Endothelial cell-derived exosomal circHIPK3 promotes the proliferation of vascular smooth muscle cells induced by high glucose via the miR-106a-5p/Foxo1/Vcam1 pathway Endothelial cells cl Mouse aortic endothelial cells (MAEC) Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 3153 34789738 Homo sapiens P2X7 promotes metastatic spreading and triggers release of miRNA-containing exosomes and microvesicles from melanoma cells Melanoma cells cl SK-MEL-28 - 18k pellet Protein|miRNA Western blotting|Small RNA sequencing|RT-PCR 2021 Differential centrifugation Microvesicles 3154 34789738 Homo sapiens P2X7 promotes metastatic spreading and triggers release of miRNA-containing exosomes and microvesicles from melanoma cells Melanoma cells cl SK-MEL-28 - 100k pellet Protein|miRNA Western blotting|Small RNA sequencing|RT-PCR 2021 Differential centrifugation|Ultracentrifugation Exosomes 3155 34789738 Homo sapiens P2X7 promotes metastatic spreading and triggers release of miRNA-containing exosomes and microvesicles from melanoma cells Melanoma cells cl Ma-Mel-19 - 18k pellet Protein|miRNA Western blotting|Small RNA sequencing|RT-PCR 2021 Differential centrifugation Microvesicles 3156 34789738 Homo sapiens P2X7 promotes metastatic spreading and triggers release of miRNA-containing exosomes and microvesicles from melanoma cells Melanoma cells cl Ma-Mel-19 - 100k pellet Protein|miRNA Western blotting|Small RNA sequencing|RT-PCR 2021 Differential centrifugation|Ultracentrifugation Exosomes 3157 34789738 Homo sapiens P2X7 promotes metastatic spreading and triggers release of miRNA-containing exosomes and microvesicles from melanoma cells Melanoma cells cl SK-MEL-28 - 18k pellet miRNA Small RNA sequencing|RT-PCR 2021 Differential centrifugation Microvesicles 3158 34789738 Homo sapiens P2X7 promotes metastatic spreading and triggers release of miRNA-containing exosomes and microvesicles from melanoma cells Melanoma cells cl SK-MEL-28 - 100k pellet miRNA Small RNA sequencing|RT-PCR 2021 Differential centrifugation|Ultracentrifugation Exosomes 3159 34789738 Homo sapiens P2X7 promotes metastatic spreading and triggers release of miRNA-containing exosomes and microvesicles from melanoma cells Melanoma cells cl Ma-Mel-19 - 18k pellet miRNA Small RNA sequencing|RT-PCR 2021 Differential centrifugation Microvesicles 3160 34789738 Homo sapiens P2X7 promotes metastatic spreading and triggers release of miRNA-containing exosomes and microvesicles from melanoma cells Melanoma cells cl Ma-Mel-19 - 100k pellet miRNA Small RNA sequencing|RT-PCR 2021 Differential centrifugation|Ultracentrifugation Exosomes 3161 34789738 Homo sapiens P2X7 promotes metastatic spreading and triggers release of miRNA-containing exosomes and microvesicles from melanoma cells Melanoma cells cl SK-MEL-28 - 18k pellet miRNA RT-PCR 2021 Differential centrifugation Microvesicles 3162 34789738 Homo sapiens P2X7 promotes metastatic spreading and triggers release of miRNA-containing exosomes and microvesicles from melanoma cells Melanoma cells cl SK-MEL-28 - 100k pellet miRNA RT-PCR 2021 Differential centrifugation|Ultracentrifugation Exosomes 3163 34789738 Homo sapiens P2X7 promotes metastatic spreading and triggers release of miRNA-containing exosomes and microvesicles from melanoma cells Melanoma cells cl Ma-Mel-19 - 18k pellet miRNA RT-PCR 2021 Differential centrifugation Microvesicles 3164 34789738 Homo sapiens P2X7 promotes metastatic spreading and triggers release of miRNA-containing exosomes and microvesicles from melanoma cells Melanoma cells cl Ma-Mel-19 - 100k pellet miRNA RT-PCR 2021 Differential centrifugation|Ultracentrifugation Exosomes 3165 34772807 Clonorchis sinensis Csi-let-7a-5p delivered by extracellular vesicles from a liver fluke activates M1-like macrophages and exacerbates biliary injuries Clonorchis sinensis ts C. sinensis-derived EVs miRNA High throughput sequencing|RT-qPCR 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 3166 34743199 Homo sapiens CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles Lymphoma cells cl SUDHL6 (GCB) - 48 h Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3167 34743199 Homo sapiens CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles Lymphoma cells cl SUDHL4 (GCB) - 48 h Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3168 34743199 Homo sapiens CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles Lymphoma cells cl OCI-LY3 (ABC) - 48 h Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3169 34743199 Homo sapiens CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles Lymphoma cells cl OCI-LY10 (ABC) - 48 h Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3170 34743199 Homo sapiens CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles Lymphoma cells cl U2932 (ABC) - 48 h Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3171 34743199 Homo sapiens CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles Lymphoma cells cl SUDHL6 (GCB) - 72 h Protein Western blotting|ELISA 2021 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3172 34743199 Homo sapiens CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles Lymphoma cells cl SUDHL4 (GCB) - 72 h Protein Western blotting|ELISA 2021 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3173 34743199 Homo sapiens CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles Lymphoma cells cl OCI-LY3 (ABC) - 72 h Protein Western blotting|ELISA 2021 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3174 34743199 Homo sapiens CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles Lymphoma cells cl OCI-LY10 (ABC) - 72 h Protein Western blotting|ELISA 2021 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3175 34743199 Homo sapiens CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles Lymphoma cells cl U2932 (ABC) - 72 h Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3176 34743199 Homo sapiens CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles Lymphoma cells cl SUDHL4 (GCB) Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3177 34743199 Homo sapiens CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles Lymphoma cells cl SUDHL4 (GCB) Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3178 34743199 Homo sapiens CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles Lymphoma cells cl SUDHL4 (GCB) Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3179 34743199 Homo sapiens CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles Lymphoma cells cl OCI-LY3 (ABC) Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3180 34743199 Homo sapiens CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles Lymphoma cells cl OCI-LY3 (ABC) Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3181 34743199 Homo sapiens CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles Lymphoma cells cl OCI-LY3 (ABC) Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3182 34743199 Homo sapiens CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles Lymphoma cells cl SUDHL6 (GCB) Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3183 34743199 Homo sapiens CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles Lymphoma cells cl SUDHL6 (GCB) Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3184 34743199 Homo sapiens CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles Lymphoma cells cl SUDHL6 (GCB) Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3185 34743199 Homo sapiens CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles Lymphoma cells cl SUDHL6 (GCB)-derived IgG2a control EVs Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3186 34743199 Homo sapiens CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles Lymphoma cells cl SUDHL6 (GCB)-derived CD20-positive EVs Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3187 34743199 Homo sapiens CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles Lymphoma cells cl SUDHL6 (GCB)-derived IgG2a control EVs Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3188 34743199 Homo sapiens CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles Lymphoma cells cl SUDHL6 (GCB)-derived CD20-positive EVs Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3189 34743199 Homo sapiens CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles Lymphoma cells cl SUDHL4 (GCB) Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3190 34743199 Homo sapiens CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles Lymphoma cells cl SUDHL4 (GCB) Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3191 34743199 Homo sapiens CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles Lymphoma cells cl SUDHL4 (GCB) Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3192 34743199 Homo sapiens CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles Lymphoma cells cl SUDHL4 (GCB) Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3193 34743199 Homo sapiens CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles Lymphoma cells cl OCI-LY10 (ABC) Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3194 34743199 Homo sapiens CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles Lymphoma cells cl OCI-LY10 (ABC) Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3195 34743199 Homo sapiens CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles Lymphoma cells cl OCI-LY10 (ABC) Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3196 34743199 Homo sapiens CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles Lymphoma cells cl OCI-LY10 (ABC) Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3197 34690112 Homo sapiens Exosome long non-coding RNA SOX2-OT contributes to ovarian cancer malignant progression by miR-181b-5p/SCD1 signaling Plasma ts Healthy donors Protein|lncRNA Western blotting|lncRNA profiling|qPCR 2021 ExoQuick Kit Exosomes 3198 34690112 Homo sapiens Exosome long non-coding RNA SOX2-OT contributes to ovarian cancer malignant progression by miR-181b-5p/SCD1 signaling Plasma ts Ovarian cancer patients Protein|lncRNA Western blotting|lncRNA profiling|qPCR 2021 ExoQuick Kit Exosomes 3199 34690112 Homo sapiens Exosome long non-coding RNA SOX2-OT contributes to ovarian cancer malignant progression by miR-181b-5p/SCD1 signaling Ovarian cancer cells cl TOV-21G Protein Western blotting 2021 ExoQuick Kit Exosomes 3200 34690112 Homo sapiens Exosome long non-coding RNA SOX2-OT contributes to ovarian cancer malignant progression by miR-181b-5p/SCD1 signaling Ovarian cancer cells cl SKOV-3 Protein Western blotting 2021 ExoQuick Kit Exosomes 3201 36754903 Mus musculus An extracellular vesicular mutant KRAS-associated protein complex promotes lung inflammation and tumor growth Lung epithelial cells cl TC1 Protein Western blotting|Mass spectrometry 2023 Differential centrifugation|Ultracentrifugation|Sucrose density gradient centrifugation Extracellular vesicles 3202 34596354 Homo sapiens Extracellular vesicles from adipose tissue-derived stem cells alleviate osteoporosis through osteoprotegerin and miR-21-5p Mesenchymal stem cells ts Adipose tissue-derived stem cells Protein|miRNA Flow cytometry|Small RNA sequencing|ddPCR 2021 Tangential flow filtration Extracellular vesicles 3203 34596354 Homo sapiens Extracellular vesicles from adipose tissue-derived stem cells alleviate osteoporosis through osteoprotegerin and miR-21-5p Mesenchymal stem cells ts Adipose tissue-derived stem cells Protein Western blotting 2021 Tangential flow filtration Extracellular vesicles 3204 34596354 Homo sapiens Extracellular vesicles from adipose tissue-derived stem cells alleviate osteoporosis through osteoprotegerin and miR-21-5p Mesenchymal stem cells ts Adipose tissue-derived stem cells Protein Western blotting 2021 Tangential flow filtration Extracellular vesicles 3205 34957415 Mus musculus Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism Melanoma cells cl B16-F1 Protein Western blotting|Mass spectrometry 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 3206 34957415 Mus musculus Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism Melanoma cells cl B16-F10 Protein Western blotting|Mass spectrometry|Flow cytometry 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 3207 34957415 Mus musculus Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism Melanoma cells cl B16-F1R2 Protein Western blotting|Mass spectrometry|Flow cytometry 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 3208 34957415 Mus musculus Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism Melanoma cells cl B16-F10 - Fraction 6 Protein Western blotting 2021 Differential centrifugation|OptiPrep density gradient centrifugation|Ultracentrifugation Small extracellular vesicles 3209 34957415 Mus musculus Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism Melanoma cells cl B16-F1R2 - Fraction 5 Protein Western blotting 2021 Differential centrifugation|OptiPrep density gradient centrifugation|Ultracentrifugation Small extracellular vesicles 3210 34957415 Mus musculus Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism Melanoma cells cl B16-F1R2 - Fraction 6 Protein Western blotting 2021 Differential centrifugation|OptiPrep density gradient centrifugation|Ultracentrifugation Small extracellular vesicles 3211 34957415 Homo sapiens Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism Melanoma cells cl SK-MEL-147 Protein Western blotting|Flow cytometry 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 3212 34957415 Homo sapiens Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism Melanoma cells cl SK-MEL-147 - Fraction 6 Protein Western blotting 2021 Differential centrifugation|OptiPrep density gradient centrifugation|Ultracentrifugation Small extracellular vesicles 3213 34957415 Homo sapiens Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism Melanoma cells cl SK-MEL-147 - Fraction 7 Protein Western blotting 2021 Differential centrifugation|OptiPrep density gradient centrifugation|Ultracentrifugation Small extracellular vesicles 3214 34957415 Homo sapiens Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism Melanocytes cl Melano3 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 3215 34957415 Homo sapiens Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism Melanocytes cl Melano4 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 3216 34957415 Homo sapiens Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism Melanoma cells cl WM164 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 3217 34957415 Homo sapiens Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism Melanoma cells cl SK-MEL-28 Protein Western blotting|Flow cytometry 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 3218 34957415 Homo sapiens Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism Melanoma cells cl SK-MEL-103 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 3219 34957415 Homo sapiens Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism Melanoma cells cl SK-MEL-147 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 3220 34957415 Homo sapiens Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism Melanoma cells cl SK-MEL-147 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 3221 34957415 Mus musculus Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism Melanoma cells cl B16-F1R2 Protein Western blotting|Mass spectrometry 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 3222 34957415 Mus musculus Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism Melanoma cells cl B16-F1R2 Protein Western blotting|Mass spectrometry 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 3223 32111843 Homo sapiens A CRISPR-Cas9-based reporter system for single-cell detection of extracellular vesicle-mediated functional transfer of RNA Breast cancer cells cl MDA-MB-231 Protein Western blotting 2020 Differential centrifugation|Tangential flow filtration|Filtration|Size exclusion chromatography Extracellular vesicles 3224 34596365 Homo sapiens Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer Lung cancer cells cl A549 miRNA RT-qPCR 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 3225 34596365 Homo sapiens Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer Lung cancer cells cl A549 miRNA RT-qPCR 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 3226 34596365 Homo sapiens Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer Lung cancer cells cl 2106T miRNA RT-qPCR 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 3227 34596365 Homo sapiens Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer Lung cancer cells cl 2106T miRNA RT-qPCR 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 3228 34596365 Homo sapiens Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer Lung cancer cells cl H1650 miRNA RT-qPCR 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 3229 34596365 Homo sapiens Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer Lung cancer cells cl H1650 miRNA RT-qPCR 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 3230 34596365 Homo sapiens Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer Lung cancer cells cl A549 miRNA RT-qPCR 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 3231 34596365 Homo sapiens Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer Lung cancer cells cl A549 miRNA RT-qPCR 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 3232 34596365 Homo sapiens Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer Lung cancer cells cl 2106T miRNA RT-qPCR 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 3233 34596365 Homo sapiens Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer Lung cancer cells cl 2106T miRNA RT-qPCR 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 3234 34596365 Homo sapiens Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer Lung cancer cells cl A549 miRNA RT-qPCR 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 3235 34596365 Homo sapiens Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer Lung cancer cells cl A549 miRNA RT-qPCR 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 3236 34596365 Homo sapiens Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer Lung cancer cells cl A549 miRNA RT-qPCR 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 3237 34596365 Homo sapiens CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles Lung cancer cells cl A549 miRNA RT-qPCR 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 3238 34596365 Homo sapiens Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer Lung cancer cells cl A549 miRNA RT-qPCR 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 3239 34596365 Homo sapiens Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer Lung cancer cells cl A549 miRNA RT-qPCR 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 3240 34596365 Homo sapiens Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer Lung cancer cells cl 2106T miRNA RT-qPCR 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 3241 34596365 Homo sapiens Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer Lung cancer cells cl 2106T miRNA RT-qPCR 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 3242 34596365 Homo sapiens Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer Lung cancer cells cl 2106T miRNA RT-qPCR 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 3243 34596365 Homo sapiens Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer Lung cancer cells cl 2106T miRNA RT-qPCR 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 3244 34596365 Homo sapiens Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer Lung cancer cells cl 2106T miRNA RT-qPCR 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 3245 34596365 Homo sapiens Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer Lung cancer cells cl 2106T miRNA RT-qPCR 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 3246 34596365 Homo sapiens Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer Lung epithelial cells cl A549-derived EVs miRNA RT-qPCR 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 3247 34596365 Homo sapiens Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer Lung epithelial cells cl A549-derived EVs miRNA RT-qPCR 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 3248 34596365 Homo sapiens Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer Lung cancer cells cl 2106T-derived EVs miRNA RT-qPCR 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 3249 34596365 Homo sapiens Small extracellular vesicle-derived miR-574-5p regulates PGE2-biosynthesis via TLR7/8 in lung cancer Lung cancer cells cl 2106T-derived EVs miRNA RT-qPCR 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 3250 34545097 Homo sapiens Exosome-mediated stable epigenetic repression of HIV-1 Embryonic kidney cells cl HEK293T Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation|Filtration Exosomes 3251 34545097 Homo sapiens Exosome-mediated stable epigenetic repression of HIV-1 Embryonic kidney cells cl HEK293T Protein|mRNA Western blotting|RT-qPCR 2021 Differential centrifugation|Ultracentrifugation|Filtration Exosomes 3252 34545097 Homo sapiens Exosome-mediated stable epigenetic repression of HIV-1 Embryonic kidney cells cl HEK293T Protein|mRNA Western blotting|RT-qPCR 2021 Differential centrifugation|Ultracentrifugation|Filtration Exosomes 3253 34580290 Mus musculus Bardet-Biedl syndrome proteins modulate the release of bioactive extracellular vesicles Kidney medullary cells cl Kidney medullary cells - ciliated Protein|miRNA Western blotting|Mass spectrometry|small RNA sequencing 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 3254 34580290 Mus musculus Bardet-Biedl syndrome proteins modulate the release of bioactive extracellular vesicles Kidney medullary cells cl Kidney medullary cells - ciliated Protein|miRNA Western blotting|Mass spectrometry|small RNA sequencing 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 3255 34580290 Mus musculus Bardet-Biedl syndrome proteins modulate the release of bioactive extracellular vesicles Kidney medullary cells cl Kidney medullary cells - ciliated Protein|miRNA Western blotting|Mass spectrometry|small RNA sequencing 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 3256 34580290 Mus musculus Bardet-Biedl syndrome proteins modulate the release of bioactive extracellular vesicles Kidney medullary cells cl Kidney medullary cells - less ciliated Protein Mass spectrometry 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 3257 34580290 Mus musculus Bardet-Biedl syndrome proteins modulate the release of bioactive extracellular vesicles Kidney medullary cells cl Kidney medullary cells - less ciliated Protein Mass spectrometry 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 3258 34580290 Mus musculus Bardet-Biedl syndrome proteins modulate the release of bioactive extracellular vesicles Kidney medullary cells cl Kidney medullary cells - less ciliated Protein Mass spectrometry 2021 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 3259 34580290 Mus musculus Bardet-Biedl syndrome proteins modulate the release of bioactive extracellular vesicles Kidney medullary cells cl Kidney medullary cells - ciliated - 10k pellet Protein Mass spectrometry 2021 Differential centrifugation Large extracellular vesicles 3260 34654817 Rattus norvegicus Damaged brain accelerates bone healing by releasing small extracellular vesicles that target osteoprogenitors Plasma ts Sham - Sprague-Dawley rat Protein|miRNA Western blotting|miRNA sequencing|qRT-PCR|Mass spectrometry 2021 ExoQuick Kit Small extracellular vesicles 3261 34654817 Rattus norvegicus Damaged brain accelerates bone healing by releasing small extracellular vesicles that target osteoprogenitors Plasma ts Post-traumatic brain injury surgery (24 h) - Sprague-Dawley rat Protein|miRNA Western blotting|miRNA sequencing|qRT-PCR|Mass spectrometry 2021 ExoQuick Kit Small extracellular vesicles 3262 34654817 Rattus norvegicus Damaged brain accelerates bone healing by releasing small extracellular vesicles that target osteoprogenitors Plasma ts Post-traumatic brain injury surgery (72 h) - Sprague-Dawley rat miRNA miRNA sequencing 2021 ExoQuick Kit Small extracellular vesicles 3263 34654817 Rattus norvegicus Damaged brain accelerates bone healing by releasing small extracellular vesicles that target osteoprogenitors Plasma ts Post-traumatic brain injury surgery (24 h) - Sprague-Dawley rat Protein Western blotting 2021 ExoQuick Kit Small extracellular vesicles 3264 34654817 Mus musculus Damaged brain accelerates bone healing by releasing small extracellular vesicles that target osteoprogenitors Microglia cl BV2 miRNA qRT-PCR 2021 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 3265 34654817 Mus musculus Damaged brain accelerates bone healing by releasing small extracellular vesicles that target osteoprogenitors Microglia cl BV2 miRNA qRT-PCR 2021 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 3266 34654817 Rattus norvegicus Damaged brain accelerates bone healing by releasing small extracellular vesicles that target osteoprogenitors Hippocampal neuronal cells ts Primary hippocampal neurons - Sprague-Dawley rat Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 3267 34654817 Rattus norvegicus Damaged brain accelerates bone healing by releasing small extracellular vesicles that target osteoprogenitors Hippocampal neuronal cells ts Primary hippocampal neurons - Sprague-Dawley rat Protein Western blotting 2021 Differential centrifugation|Filtration|Ultracentrifugation Small extracellular vesicles 3268 34654817 Rattus norvegicus Damaged brain accelerates bone healing by releasing small extracellular vesicles that target osteoprogenitors Plasma ts Liver injury - Sprague-Dawley rat Protein Western blotting 2021 ExoQuick Kit Small extracellular vesicles 3269 34593794 Mus musculus A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis Melanoma cells cl B16-F10 Protein Western blotting 2021 Differential centrifugation|Total Exosome Isolation Reagent Exosomes 3270 34593794 Mus musculus A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis Melanoma cells cl|ts C57BL/6 bearing B16-F10 tumour Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Exosomes 3271 34593794 Mus musculus A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis Melanoma cells cl B16-F10 Protein Western blotting 2021 Differential centrifugation|Total Exosome Isolation Reagent Exosomes 3272 34593794 Mus musculus A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis Melanoma cells cl B16-F10 Protein Western blotting 2021 Differential centrifugation|Total Exosome Isolation Reagent Exosomes 3273 34593794 Mus musculus A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis Melanoma cells cl B16-F10 Protein Western blotting 2021 Differential centrifugation|Total Exosome Isolation Reagent Exosomes 3274 34593794 Mus musculus A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis Melanoma cells cl B16-F10 Protein Western blotting 2021 Differential centrifugation|Total Exosome Isolation Reagent Exosomes 3275 34593794 Mus musculus A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis Melanoma cells cl|ts C57BL/6 bearing B16-F10 tumour Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Exosomes 3276 34593794 Mus musculus A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis Melanoma cells cl|ts C57BL/6 bearing B16-F10 tumour Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Exosomes 3277 34593794 Mus musculus A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis Melanoma cells cl|ts C57BL/6 bearing B16-F10 tumour Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Exosomes 3278 34593794 Mus musculus A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis Melanoma cells cl|ts C57BL/6 bearing B16-F10 tumour Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Exosomes 3279 34593794 Mus musculus A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis Melanoma cells cl B16-F10 Protein Western blotting 2021 Differential centrifugation|Total Exosome Isolation Reagent Exosomes 3280 34593794 Mus musculus A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis Melanoma cells cl B16-F10 Protein Western blotting 2021 Differential centrifugation|Total Exosome Isolation Reagent Exosomes 3281 34593794 Mus musculus A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis Melanoma cells cl B16-F10 Protein Western blotting 2021 Differential centrifugation|Total Exosome Isolation Reagent Exosomes 3282 34593794 Mus musculus A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis Melanoma cells cl B16-F10 Protein Western blotting 2021 Differential centrifugation|Total Exosome Isolation Reagent Exosomes 3283 34593794 Mus musculus A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis Melanoma cells cl B16-F10 Protein Western blotting 2021 Differential centrifugation|Total Exosome Isolation Reagent Exosomes 3284 34593794 Mus musculus A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis Melanoma cells cl B16-F10 Protein Western blotting 2021 Differential centrifugation|Total Exosome Isolation Reagent Exosomes 3285 34593794 Mus musculus A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis Melanoma cells cl B16-F10 Protein Western blotting 2021 Differential centrifugation|Total Exosome Isolation Reagent Exosomes 3286 34593794 Mus musculus A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis Melanoma cells cl B16-F10 Protein Western blotting 2021 Differential centrifugation|Total Exosome Isolation Reagent Exosomes 3287 32848136 Homo sapiens ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells Breast cancer cells cl MDA-MB-231 Protein Western blotting|Mass spectrometry 2020 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 3288 32848136 Homo sapiens ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells Breast cancer cells cl MDA-MB-231 Protein Western blotting|Mass spectrometry 2020 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 3289 32848136 Homo sapiens ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells Breast cancer cells cl MDA-MB-231 - Fraction 1 Protein Western blotting 2020 Differential centrifugation|OptiPrep density gradient centrifugation|Ultracentrifugation Small extracellular vesicles 3290 32848136 Homo sapiens ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells Breast cancer cells cl MDA-MB-231 - Fraction 5 Protein Western blotting 2020 Differential centrifugation|OptiPrep density gradient centrifugation|Ultracentrifugation Small extracellular vesicles 3291 32848136 Homo sapiens ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells Breast cancer cells cl MDA-MB-231 - Fraction 6 Protein Western blotting 2020 Differential centrifugation|OptiPrep density gradient centrifugation|Ultracentrifugation Small extracellular vesicles 3292 32848136 Homo sapiens ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells Breast cancer cells cl MDA-MB-231 - Fraction 7 Protein Western blotting 2020 Differential centrifugation|OptiPrep density gradient centrifugation|Ultracentrifugation Small extracellular vesicles 3293 32848136 Homo sapiens ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells Breast cancer cells cl MDA-MB-231 - Fraction 8 Protein Western blotting 2020 Differential centrifugation|OptiPrep density gradient centrifugation|Ultracentrifugation Small extracellular vesicles 3294 32848136 Homo sapiens ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells Breast cancer cells cl MDA-MB-231 - Fraction 9 Protein Western blotting 2020 Differential centrifugation|OptiPrep density gradient centrifugation|Ultracentrifugation Small extracellular vesicles 3295 32848136 Homo sapiens ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells Breast cancer cells cl MDA-MB-231 - Fraction 1 Protein Western blotting 2020 Differential centrifugation|OptiPrep density gradient centrifugation|Ultracentrifugation Small extracellular vesicles 3296 32848136 Homo sapiens ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells Breast cancer cells cl MDA-MB-231 - Fraction 3 Protein Western blotting 2020 Differential centrifugation|OptiPrep density gradient centrifugation|Ultracentrifugation Small extracellular vesicles 3297 32848136 Homo sapiens ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells Breast cancer cells cl MDA-MB-231 - Fraction 4 Protein Western blotting 2020 Differential centrifugation|OptiPrep density gradient centrifugation|Ultracentrifugation Small extracellular vesicles 3298 32848136 Homo sapiens ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells Breast cancer cells cl MDA-MB-231 - Fraction 5 Protein Western blotting 2020 Differential centrifugation|OptiPrep density gradient centrifugation|Ultracentrifugation Small extracellular vesicles 3299 32848136 Homo sapiens ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells Breast cancer cells cl MDA-MB-231 - Fraction 6 Protein Western blotting 2020 Differential centrifugation|OptiPrep density gradient centrifugation|Ultracentrifugation Small extracellular vesicles 3300 32848136 Homo sapiens ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells Breast cancer cells cl MDA-MB-231 - Fraction 7 Protein Western blotting 2020 Differential centrifugation|OptiPrep density gradient centrifugation|Ultracentrifugation Small extracellular vesicles 3301 32848136 Homo sapiens ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells Breast cancer cells cl MDA-MB-231 - Fraction 8 Protein Western blotting 2020 Differential centrifugation|OptiPrep density gradient centrifugation|Ultracentrifugation Small extracellular vesicles 3302 32848136 Homo sapiens ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells Breast cancer cells cl MDA-MB-231 - Fraction 9 Protein Western blotting 2020 Differential centrifugation|OptiPrep density gradient centrifugation|Ultracentrifugation Small extracellular vesicles 3303 32848136 Homo sapiens ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells Breast cancer cells cl MDA-MB-231 Protein Western blotting 2020 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 3304 32848136 Homo sapiens ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells Breast cancer cells cl MDA-MB-231 Protein Western blotting 2020 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 3305 32848136 Homo sapiens ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells Breast cancer cells cl MCF7 Protein Western blotting 2020 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 3306 32848136 Homo sapiens ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells Breast cancer cells cl MCF7 Protein Western blotting 2020 Differential centrifugation|Ultracentrifugation Small extracellular vesicles 3307 32139701 Homo sapiens Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation Plasma ts Healthy volunteers Protein Western blotting|ELISA 2020 Differential centrifugation|Ultracentrifugation Extracellular vesicles 3308 32139701 Homo sapiens Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation Plasma ts Non-metastatic colorectal cancer patients Protein Western blotting|ELISA 2020 Differential centrifugation|Ultracentrifugation Extracellular vesicles 3309 32139701 Homo sapiens Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation Plasma ts Metastatic colorectal cancer patients Protein Western blotting 2020 Differential centrifugation|Ultracentrifugation Extracellular vesicles 3310 32139701 Homo sapiens Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation Plasma ts Colorectal cancer patients with lung metastasis Protein ELISA 2020 Differential centrifugation|Ultracentrifugation Extracellular vesicles 3311 32139701 Homo sapiens Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation Plasma ts Colorectal cancer patients with liver metastasis Protein ELISA 2020 Differential centrifugation|Ultracentrifugation Extracellular vesicles 3312 32139701 Homo sapiens Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation Colorectal cancer cells cl SW620 Protein Western blotting 2020 Differential centrifugation|Ultracentrifugation Extracellular vesicles 3313 32139701 Homo sapiens Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation Colorectal cancer cells cl SW620 Protein Western blotting 2020 Differential centrifugation|Ultracentrifugation Extracellular vesicles 3314 32139701 Homo sapiens Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation Colorectal cancer cells cl SW620 Protein Western blotting 2020 Differential centrifugation|Ultracentrifugation Extracellular vesicles 3315 32139701 Homo sapiens Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation Colorectal cancer cells cl SW620 Protein Western blotting 2020 Differential centrifugation|Ultracentrifugation Extracellular vesicles 3316 32139701 Homo sapiens Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation Colorectal cancer cells cl SW620 Protein Western blotting 2020 Differential centrifugation|Ultracentrifugation Extracellular vesicles 3317 32139701 Homo sapiens Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation Colorectal cancer cells cl SW620 Protein Western blotting 2020 Differential centrifugation|Ultracentrifugation Extracellular vesicles 3318 32139701 Homo sapiens Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation Colorectal cancer cells cl SW620 Protein Western blotting 2020 Differential centrifugation|Ultracentrifugation Extracellular vesicles 3319 32139701 Homo sapiens Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation Colorectal cancer cells cl SW620 Protein Western blotting 2020 Differential centrifugation|Ultracentrifugation Extracellular vesicles 3320 32139701 Homo sapiens Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation Colorectal cancer cells cl SW620 Protein Western blotting 2020 Differential centrifugation|Ultracentrifugation Extracellular vesicles 3321 32139701 Homo sapiens Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation Colorectal cancer cells cl SW620 Protein Western blotting 2020 Differential centrifugation|Ultracentrifugation Extracellular vesicles 3322 32139701 Homo sapiens Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation Colorectal cancer cells cl SW620 Protein Western blotting 2020 Differential centrifugation|Ultracentrifugation Extracellular vesicles 3323 32139701 Homo sapiens Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation Colorectal cancer cells cl Caco2 Protein Western blotting 2020 Differential centrifugation|Ultracentrifugation Extracellular vesicles 3324 32139701 Homo sapiens Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation Colorectal cancer cells cl SW620 Protein Western blotting 2020 Differential centrifugation|Ultracentrifugation Extracellular vesicles 3325 32139701 Homo sapiens Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation Colorectal cancer cells cl HCT8 Protein Western blotting 2020 Differential centrifugation|Ultracentrifugation Extracellular vesicles 3326 32139701 Homo sapiens Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation Colorectal cancer cells cl LoVo Protein Western blotting 2020 Differential centrifugation|Ultracentrifugation Extracellular vesicles 3327 32139701 Homo sapiens Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation Colorectal cancer cells cl HCT116 Protein Western blotting 2020 Differential centrifugation|Ultracentrifugation Extracellular vesicles 3328 32139701 Homo sapiens Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation Colorectal cancer cells cl SW480 Protein Western blotting 2020 Differential centrifugation|Ultracentrifugation Extracellular vesicles 3329 32139701 Homo sapiens Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation Colorectal cancer cells cl LS174T Protein Western blotting 2020 Differential centrifugation|Ultracentrifugation Extracellular vesicles 3330 32139701 Homo sapiens Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation Colorectal cancer cells cl HT29 Protein Western blotting 2020 Differential centrifugation|Ultracentrifugation Extracellular vesicles 3331 32139701 Homo sapiens Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation Colon epithelial cells cl NCM-460 Protein Western blotting 2020 Differential centrifugation|Ultracentrifugation Extracellular vesicles 3332 34887515 Homo sapiens Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Lung cancer cells cl Calu-3 Protein Western blotting 2021 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Ultracentrifugation Small extracellular vesicles 3333 34887515 Homo sapiens Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Lung cancer cells cl Calu-3 Protein Western blotting 2021 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Ultracentrifugation Exomeres 3334 34887515 Homo sapiens Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Lung cancer cells cl Calu-3 Protein Western blotting 2021 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Ultracentrifugation Supermeres 3335 34887515 Homo sapiens Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Colorectal cancer cells cl LIM1215 Protein Western blotting 2021 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Ultracentrifugation Small extracellular vesicles 3336 34887515 Homo sapiens Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Colorectal cancer cells cl LIM1215 Protein Western blotting 2021 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Ultracentrifugation Exomeres 3337 34887515 Homo sapiens Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Colorectal cancer cells cl LIM1215 Protein Western blotting 2021 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Ultracentrifugation Supermeres 3338 34887515 Homo sapiens Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Colorectal cancer cells cl DiFi Protein|miRNA Western blotting|Mass spectrometry|RNA sequencing 2021 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Ultracentrifugation|OptiPrep density gradient centrifugation Small extracellular vesicles 3339 34887515 Homo sapiens Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Colorectal cancer cells cl DiFi Protein|miRNA Western blotting|Mass spectrometry|ELISA|RNA sequencing 2021 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Ultracentrifugation Exomeres 3340 34887515 Homo sapiens Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Colorectal cancer cells cl DiFi Protein|miRNA Western blotting|Mass spectrometry|ELISA|RNA sequencing 2021 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Ultracentrifugation Supermeres 3341 34887515 Homo sapiens Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Plasma ts Colorectal cancer patients Protein Western blotting|ELISA 2021 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Ultracentrifugation Small extracellular vesicles 3342 34887515 Homo sapiens Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Plasma ts Colorectal cancer patients Protein Western blotting|ELISA 2021 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Ultracentrifugation Exomeres 3343 34887515 Homo sapiens Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Plasma ts Colorectal cancer patients Protein Western blotting|ELISA 2021 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Ultracentrifugation Supermeres 3344 34887515 Homo sapiens Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Pancreatic cancer cells cl PANC-1 Protein Western blotting 2021 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Ultracentrifugation Small extracellular vesicles 3345 34887515 Homo sapiens Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Pancreatic cancer cells cl PANC-1 Protein Western blotting|ELISA 2021 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Ultracentrifugation Exomeres 3346 34887515 Homo sapiens Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Pancreatic cancer cells cl PANC-1 Protein Western blotting|Mass spectrometry|ELISA 2021 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Ultracentrifugation Supermeres 3347 34887515 Homo sapiens Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Colorectal cancer cells cl DiFi Protein Western blotting|Mass spectrometry 2021 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Ultracentrifugation|OptiPrep density gradient centrifugation Non-vesicular nanoparticles 3348 34887515 Homo sapiens Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Breast cancer cells cl MDA-MB-231 Protein Western blotting|Mass spectrometry|ELISA 2021 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Ultracentrifugation Small extracellular vesicles 3349 34887515 Homo sapiens Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Breast cancer cells cl MDA-MB-231 Protein Western blotting|Mass spectrometry|ELISA 2021 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Ultracentrifugation Exomeres 3350 34887515 Homo sapiens Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Breast cancer cells cl MDA-MB-231 Protein Western blotting|Mass spectrometry|ELISA 2021 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Ultracentrifugation Supermeres 3351 34887515 Homo sapiens Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Colorectal cancer cells cl HCA-7 SC Protein Western blotting 2021 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Ultracentrifugation Small extracellular vesicles 3352 34887515 Homo sapiens Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Colorectal cancer cells cl HCA-7 SC Protein Western blotting 2021 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Ultracentrifugation Exomeres 3353 34887515 Homo sapiens Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Colorectal cancer cells cl HCA-7 SC Protein Western blotting 2021 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Ultracentrifugation Supermeres 3354 34887515 Homo sapiens Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Retinal endothelial cells cl HREC Protein Western blotting 2021 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Ultracentrifugation Small extracellular vesicles 3355 34887515 Homo sapiens Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Retinal endothelial cells cl HREC Protein Western blotting 2021 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Ultracentrifugation Exomeres 3356 34887515 Homo sapiens Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Retinal endothelial cells cl HREC Protein Western blotting 2021 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Ultracentrifugation Supermeres 3357 34887515 Homo sapiens Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Plasma cl Control individuals Protein Western blotting 2021 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Ultracentrifugation Small extracellular vesicles 3358 34887515 Homo sapiens Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Plasma ts Control individuals Protein ELISA 2021 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Ultracentrifugation Supermeres 3359 34887515 Homo sapiens Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Breast cancer cells cl LM2-4175 Protein Western blotting 2021 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Ultracentrifugation Small extracellular vesicles 3360 34887515 Homo sapiens Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Breast cancer cells cl LM2-4175 Protein Western blotting 2021 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Ultracentrifugation Exomeres 3361 34887515 Homo sapiens Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Breast cancer cells cl LM2-4175 Protein Western blotting 2021 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Ultracentrifugation Supermeres 3362 34887515 Homo sapiens Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Colorectal cancer cells cl HCA-7 CC Protein Western blotting 2021 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Ultracentrifugation Small extracellular vesicles 3363 34887515 Homo sapiens Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Colorectal cancer cells cl HCA-7 CC Protein Western blotting 2021 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Ultracentrifugation Exomeres 3364 34887515 Homo sapiens Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Colorectal cancer cells cl HCA-7 CC Protein Western blotting 2021 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Ultracentrifugation Supermeres 3365 34887515 Homo sapiens Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Colon cancer cells cl LS174T Protein Western blotting 2021 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Ultracentrifugation Small extracellular vesicles 3366 34887515 Homo sapiens Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Colon cancer cells cl LS174T Protein Western blotting 2021 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Ultracentrifugation Exomeres 3367 34887515 Homo sapiens Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Colon cancer cells cl LS174T Protein Western blotting 2021 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Ultracentrifugation Supermeres 3368 34887515 Homo sapiens Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Colon cancer cells cl DiFi-derived EGFR/CD81-positive sEVs - dim (FAVS) Protein Western blotting 2021 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Ultracentrifugation Exosomes 3369 34887515 Homo sapiens Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Colon cancer cells cl DiFi-derived EGFR/CD81-positive sEVs - bright (FAVS) Protein Western blotting 2021 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Ultracentrifugation Exosomes 3370 34887515 Homo sapiens Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Colon cancer cells cl DKO-1 Protein Western blotting 2021 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Ultracentrifugation Small extracellular vesicles 3371 34887515 Homo sapiens Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Glioblastoma cells cl Gli36vIII Protein Western blotting 2021 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Ultracentrifugation Small extracellular vesicles 3372 33510128 Mus musculus Extracellular vesicles-released parathyroid hormone-related protein from Lewis lung carcinoma induces lipolysis and adipose tissue browning in cancer cachexia Lung cancer cells cl LLC Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 3373 33510128 Mus musculus Extracellular vesicles-released parathyroid hormone-related protein from Lewis lung carcinoma induces lipolysis and adipose tissue browning in cancer cachexia Colon cancer cells cl C26 Protein Western blotting 2021 Differential centrifugation|Ultracentrifugation Extracellular vesicles 3374 34931471 Mus musculus Extracellular vesicles derived from tumour cells as a trigger of energy crisis in the skeletal muscle Plasma cl|ts BALB/C - subcutaneously implanted with C26 cells miRNA Small RNA sequencing|ddPCR 2022 Differential centrifugation|Ultracentrifugation Microvesicles 3375 34931471 Mus musculus Extracellular vesicles derived from tumour cells as a trigger of energy crisis in the skeletal muscle Colon cancer cells cl C26 miRNA Small RNA sequencing 2022 Differential centrifugation|Ultracentrifugation Microvesicles 3376 34931471 Mus musculus Extracellular vesicles derived from tumour cells as a trigger of energy crisis in the skeletal muscle Plasma ts BALB/C - control miRNA ddPCR 2022 Differential centrifugation|Ultracentrifugation Microvesicles 3377 36581870 Mus musculus Exosomal IL-8 derived from Lung Cancer and Colon Cancer cells induced adipocyte atrophy via NF-κB signaling pathway Lung cancer cells cl LLC Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation|Qiagen Exosome Purification Kit Extracellular vesicles 3378 36581870 Mus musculus Exosomal IL-8 derived from Lung Cancer and Colon Cancer cells induced adipocyte atrophy via NF-κB signaling pathway Colon cancer cells cl C26 Protein Western blotting 2022 Differential centrifugation|Ultracentrifugation|Qiagen Exosome Purification Kit Extracellular vesicles 3379 31848325 Rattus norvegicus Insulin-like growth factor-1 enchances neuroprotective effects of neural stem cell exosomes after spinal cord injury via an miR-219a-2-3p/YY1 mechanism Neural stem cells ts Cerebral cortex-derived NSCs Protein|miRNA Western blotting|RNA sequencing|qRT-PCR 2019 Differential centrifugation|Ultracentrifugation Exosomes 3380 31848325 Rattus norvegicus Insulin-like growth factor-1 enchances neuroprotective effects of neural stem cell exosomes after spinal cord injury via an miR-219a-2-3p/YY1 mechanism Neural stem cells ts Cerebral cortex-derived NSCs Protein|miRNA Western blotting|RNA sequencing|qRT-PCR 2019 Differential centrifugation|Ultracentrifugation Exosomes 3381 31732668 Homo sapiens Label-free visualization and characterization of extracellular vesicles in breast cancer Breast cancer cells cl MDA-MB-231 Metabolite Multiphoton microscopy 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 3382 31732668 Homo sapiens Label-free visualization and characterization of extracellular vesicles in breast cancer Breast cancer cells cl MCF-7 Metabolite Multiphoton microscopy 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 3383 31732668 Homo sapiens Label-free visualization and characterization of extracellular vesicles in breast cancer Mammary epithelial cells cl MCF10A Metabolite Multiphoton microscopy 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 3384 31732668 Rattus norvegicus Label-free visualization and characterization of extracellular vesicles in breast cancer Mammary epithelial cells ts Healthy mammary tissue - Wistar Furth rat Metabolite Multiphoton microscopy 2019 - Extracellular vesicles 3385 31732668 Rattus norvegicus Label-free visualization and characterization of extracellular vesicles in breast cancer Breast cancer cells ts NMU-induced mammary tumour - Wistar Furth rat Metabolite Multiphoton microscopy 2019 - Extracellular vesicles 3386 31732668 Homo sapiens Label-free visualization and characterization of extracellular vesicles in breast cancer Mammary epithelial cells ts Healthy donor-derived mammary tissue Metabolite Multiphoton microscopy 2019 - Extracellular vesicles 3387 31732668 Homo sapiens Label-free visualization and characterization of extracellular vesicles in breast cancer Breast cancer cells ts Breast cancer patient-derived invasive ductal carcinoma tissue Metabolite Multiphoton microscopy 2019 - Extracellular vesicles 3388 31732668 Homo sapiens Label-free visualization and characterization of extracellular vesicles in breast cancer Breast cancer cells ts Breast cancer patients - stage 1 Metabolite Multiphoton microscopy 2019 - Extracellular vesicles 3389 31732668 Homo sapiens Label-free visualization and characterization of extracellular vesicles in breast cancer Breast cancer cells ts Breast cancer patients - stage 2 Metabolite Multiphoton microscopy 2019 - Extracellular vesicles 3390 31732668 Homo sapiens Label-free visualization and characterization of extracellular vesicles in breast cancer Breast cancer cells ts Breast cancer patients - stage 3 Metabolite Multiphoton microscopy 2019 - Extracellular vesicles 3391 31827089 Lactobacillus crispatus Extracellular vesicles from symbiotic vaginal lactobacilli inhibit HIV-1 infection of human tissues Lactobacillus crispatus cl L. crispatus - BC3 Metabolite H-NMR spectroscopy 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 3392 31827089 Lactobacillus crispatus Extracellular vesicles from symbiotic vaginal lactobacilli inhibit HIV-1 infection of human tissues Lactobacillus crispatus cl L. crispatus - BC5 Protein|Metabolite H-NMR spectroscopy|Mass spectrometry 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 3393 31827089 Lactobacillus gasseri Extracellular vesicles from symbiotic vaginal lactobacilli inhibit HIV-1 infection of human tissues Lactobacillus gasseri cl L. gasseri - BC12 Protein|Metabolite H-NMR spectroscopy|Mass spectrometry 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 3394 31827089 Lactobacillus gasseri Extracellular vesicles from symbiotic vaginal lactobacilli inhibit HIV-1 infection of human tissues Lactobacillus gasseri cl L. gasseri - BC13 Metabolite H-NMR spectroscopy 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 3395 31792209 Homo sapiens Eliminating blood oncogenic exosomes into the small intestine with aptamer-functionalized nanoparticles Lung cancer cells cl A549 Protein Flow cytometry 2019 Differential centrifugation|Ultracentrifugation Exosomes 3396 31792209 Homo sapiens Eliminating blood oncogenic exosomes into the small intestine with aptamer-functionalized nanoparticles Fibroblasts cl human embryonic lung fibroblast (HELF) Protein Flow cytometry 2019 Differential centrifugation|Ultracentrifugation Exosomes 3397 31054213 Homo sapiens Phosphoproteome Profiling of Isogenic Cancer Cell-Derived Exosome Reveals HSP90 as a Potential Marker for Human Cholangiocarcinoma Cholangiocarcinoma cells cl KKU-M213 Protein Western blotting|Mass spectrometry 2019 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Ultracentrifugation|Sucrose density gradient centrifugation Exosomes 3398 31054213 Homo sapiens Phosphoproteome Profiling of Isogenic Cancer Cell-Derived Exosome Reveals HSP90 as a Potential Marker for Human Cholangiocarcinoma Cholangiocarcinoma cells cl KKU-M213D5 Protein Western blotting|Mass spectrometry 2019 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Ultracentrifugation|Sucrose density gradient centrifugation Exosomes 3399 31054213 Homo sapiens Phosphoproteome Profiling of Isogenic Cancer Cell-Derived Exosome Reveals HSP90 as a Potential Marker for Human Cholangiocarcinoma Cholangiocarcinoma cells cl KKU-M213 - in-gel digestion Protein Mass spectrometry 2019 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Ultracentrifugation|Sucrose density gradient centrifugation Exosomes 3400 31054213 Homo sapiens Phosphoproteome Profiling of Isogenic Cancer Cell-Derived Exosome Reveals HSP90 as a Potential Marker for Human Cholangiocarcinoma Cholangiocarcinoma cells cl KKU-M213D5 - in-gel digestion Protein Mass spectrometry 2019 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Ultracentrifugation|Sucrose density gradient centrifugation Exosomes 3401 31054213 Homo sapiens Phosphoproteome Profiling of Isogenic Cancer Cell-Derived Exosome Reveals HSP90 as a Potential Marker for Human Cholangiocarcinoma Cholangiocarcinoma cells cl KKU-M213 - in-solution digestion Protein Mass spectrometry 2019 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Ultracentrifugation|Sucrose density gradient centrifugation Exosomes 3402 31054213 Homo sapiens Phosphoproteome Profiling of Isogenic Cancer Cell-Derived Exosome Reveals HSP90 as a Potential Marker for Human Cholangiocarcinoma Cholangiocarcinoma cells cl KKU-M213D5 - in-solution digestion Protein Mass spectrometry 2019 Differential centrifugation|Filtration|Centrifugal ultrafiltration|Ultracentrifugation|Sucrose density gradient centrifugation Exosomes 3403 31712780 Homo sapiens Non-reversible tissue fixation retains extracellular vesicles for in situ imaging Embryonic kidney cells cl HEK293 Protein Western blotting 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 3404 31712780 Bos taurus Non-reversible tissue fixation retains extracellular vesicles for in situ imaging Vitreous ts Bovine vitreous humor Protein Mass spectrometry 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 3405 31666321 Drosophila melanogaster Glia-derived exosomal miR-274 targets Sprouty in trachea and synaptic boutons to modulate growth and response to hypoxia Embryonic cells cl S2 Protein|miRNA RT-PCR|Western blotting 2019 Differential centrifugation|ExoQuick Kit Exosomes 3406 31666321 Drosophila melanogaster Glia-derived exosomal miR-274 targets Sprouty in trachea and synaptic boutons to modulate growth and response to hypoxia Hemolymph ts Circulating hemolymph Protein|miRNA RT-PCR|Western blotting 2019 Differential centrifugation|ExoQuick Kit Exosomes 3407 31666321 Drosophila melanogaster Glia-derived exosomal miR-274 targets Sprouty in trachea and synaptic boutons to modulate growth and response to hypoxia Hemolymph ts Circulating hemolymph Protein Western blotting 2019 Differential centrifugation|ExoQuick Kit Exosomes 3408 31666321 Drosophila melanogaster Glia-derived exosomal miR-274 targets Sprouty in trachea and synaptic boutons to modulate growth and response to hypoxia Hemolymph ts Circulating hemolymph miRNA RT-PCR 2019 Differential centrifugation|ExoQuick Kit Exosomes 3409 31666321 Drosophila melanogaster Glia-derived exosomal miR-274 targets Sprouty in trachea and synaptic boutons to modulate growth and response to hypoxia Hemolymph ts Circulating hemolymph miRNA RT-PCR 2019 Differential centrifugation|ExoQuick Kit Exosomes 3410 31666321 Drosophila melanogaster Glia-derived exosomal miR-274 targets Sprouty in trachea and synaptic boutons to modulate growth and response to hypoxia Hemolymph ts Circulating hemolymph miRNA RT-PCR 2019 Differential centrifugation|ExoQuick Kit Exosomes 3411 31666321 Drosophila melanogaster Glia-derived exosomal miR-274 targets Sprouty in trachea and synaptic boutons to modulate growth and response to hypoxia Hemolymph ts Circulating hemolymph miRNA RT-PCR 2019 Differential centrifugation|ExoQuick Kit Exosomes 3412 31666321 Drosophila melanogaster Glia-derived exosomal miR-274 targets Sprouty in trachea and synaptic boutons to modulate growth and response to hypoxia Hemolymph ts Circulating hemolymph miRNA RT-PCR 2019 Differential centrifugation|ExoQuick Kit Exosomes 3413 31666321 Drosophila melanogaster Glia-derived exosomal miR-274 targets Sprouty in trachea and synaptic boutons to modulate growth and response to hypoxia Hemolymph ts Circulating hemolymph miRNA RT-PCR 2019 Differential centrifugation|ExoQuick Kit Exosomes 3414 31666321 Drosophila melanogaster Glia-derived exosomal miR-274 targets Sprouty in trachea and synaptic boutons to modulate growth and response to hypoxia Hemolymph ts Circulating hemolymph miRNA RT-PCR 2019 Differential centrifugation|ExoQuick Kit Exosomes 3415 33391636 Homo sapiens Extracellular vesicles containing ACE2 efficiently prevent infection by SARS-CoV-2 Spike protein-containing virus Colorectal cancer cells cl Caco-2 Protein Western blotting 2020 Differential centrifugation|Size exclusion chromatography|Centrifugal ultrafiltration Extracellular vesicles 3416 33391636 Homo sapiens Extracellular vesicles containing ACE2 efficiently prevent infection by SARS-CoV-2 Spike protein-containing virus Lung cancer cells cl Calu-3 Protein Western blotting 2020 Differential centrifugation|Size exclusion chromatography|Centrifugal ultrafiltration Extracellular vesicles 3417 33391636 Homo sapiens Extracellular vesicles containing ACE2 efficiently prevent infection by SARS-CoV-2 Spike protein-containing virus Embryonic kidney cells cl 293FT Protein Western blotting 2020 Differential centrifugation|Size exclusion chromatography|Centrifugal ultrafiltration Extracellular vesicles 3418 33391636 Homo sapiens Extracellular vesicles containing ACE2 efficiently prevent infection by SARS-CoV-2 Spike protein-containing virus Embryonic kidney cells cl 293FT Protein Western blotting|ELISA 2020 Differential centrifugation|Size exclusion chromatography|Centrifugal ultrafiltration Extracellular vesicles 3419 33391636 Homo sapiens Extracellular vesicles containing ACE2 efficiently prevent infection by SARS-CoV-2 Spike protein-containing virus Embryonic kidney cells cl 293FT Protein Western blotting|ELISA 2020 Differential centrifugation|Size exclusion chromatography|Centrifugal ultrafiltration Extracellular vesicles 3420 32341770 Homo sapiens DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Pancreatic cancer cells cl MIA PaCa-2 - Elution 4-6 Protein Western blotting 2020 Centrifugal ultrafiltration|Size exclusion chromatography Extracellular vesicles 3421 32341770 Homo sapiens DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Pancreatic cancer cells cl MIA PaCa-2 - Elution 7-9 Protein Western blotting 2020 Centrifugal ultrafiltration|Size exclusion chromatography Extracellular vesicles 3422 32341770 Homo sapiens DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Pancreatic cancer cells cl MIA PaCa-2 - Elution 10-12 Protein Western blotting 2020 Centrifugal ultrafiltration|Size exclusion chromatography Extracellular vesicles 3423 32341770 Homo sapiens DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Pancreatic cancer cells cl MIA PaCa-2 - Elution 13-15 Protein Western blotting 2020 Centrifugal ultrafiltration|Size exclusion chromatography Extracellular vesicles 3424 32341770 Homo sapiens DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Pancreatic cancer cells cl MIA PaCa-2 - Elution 16-18 Protein Western blotting 2020 Centrifugal ultrafiltration|Size exclusion chromatography Extracellular vesicles 3425 32341770 Homo sapiens DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Pancreatic cancer cells cl MIA PaCa-2 - Elution 19-21 Protein Western blotting 2020 Centrifugal ultrafiltration|Size exclusion chromatography Extracellular vesicles 3426 32341770 Homo sapiens DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Pancreatic cancer cells cl MIA PaCa-2 Protein Western blotting 2020 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3427 32341770 Homo sapiens DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Pancreatic cancer cells cl MIA PaCa-2 Protein Western blotting 2020 Differential centrifugation|ExoQuick Kit Extracellular vesicles 3428 32341770 Homo sapiens DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Pancreatic cancer cells cl MIA PaCa-2 Protein Western blotting 2020 Differential centrifugation|ExoQuick Kit Extracellular vesicles 3429 32341770 Homo sapiens DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Pancreatic cancer cells cl MIA PaCa-2 Protein Western blotting 2020 Differential centrifugation|ExoQuick Kit Extracellular vesicles 3430 32341770 Homo sapiens DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Pancreatic cancer cells cl MIA PaCa-2 Protein Western blotting 2020 Differential centrifugation|ExoQuick Kit Extracellular vesicles 3431 32341770 Homo sapiens DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Pancreatic cancer cells cl MIA PaCa-2 Protein Western blotting 2020 Differential centrifugation|ExoQuick Kit Extracellular vesicles 3432 32341770 Homo sapiens DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Pancreatic cancer cells cl MIA PaCa-2 Protein Western blotting 2020 Centrifugal ultrafiltration|Size exclusion chromatography Extracellular vesicles 3433 32341770 Homo sapiens DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Pancreatic cancer cells cl MIA PaCa-2 Protein Western blotting 2020 Centrifugal ultrafiltration|Size exclusion chromatography Extracellular vesicles 3434 32341770 Homo sapiens DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Pancreatic cancer cells cl MIA PaCa-2 Protein Western blotting 2020 Centrifugal ultrafiltration|Size exclusion chromatography Extracellular vesicles 3435 32341770 Homo sapiens DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Pancreatic cancer cells cl AsPC-1 Protein Western blotting 2020 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3436 32341770 Homo sapiens DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Pancreatic cancer cells cl AsPC-1 Protein Western blotting 2020 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3437 32341770 Homo sapiens DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Pancreatic cancer cells cl AsPC-1 Protein Western blotting 2020 Differential centrifugation|Filtration|Ultracentrifugation Microvesicles 3438 32341770 Homo sapiens DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Pancreatic cancer cells cl AsPC-1 Protein Western blotting 2020 Differential centrifugation|Filtration|Ultracentrifugation Microvesicles 3439 32341770 Homo sapiens DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Pancreatic cancer cells cl AsPC-1 Protein Western blotting 2020 Differential centrifugation|ExoQuick Kit Extracellular vesicles 3440 32341770 Homo sapiens DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Pancreatic cancer cells cl AsPC-1 Protein Western blotting 2020 Differential centrifugation|ExoQuick Kit Extracellular vesicles 3441 32341770 Homo sapiens DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Pancreatic cancer cells cl MIA PaCa-2 Protein Western blotting 2020 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3442 32341770 Homo sapiens DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Pancreatic cancer cells cl MIA PaCa-2 Protein Western blotting 2020 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3443 32341770 Homo sapiens DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Pancreatic cancer cells cl MIA PaCa-2 Protein Western blotting 2020 Differential centrifugation|ExoQuick Kit Extracellular vesicles 3444 32341770 Homo sapiens DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Pancreatic cancer cells cl MIA PaCa-2 Protein Western blotting 2020 Differential centrifugation|ExoQuick Kit Extracellular vesicles 3445 32341770 Homo sapiens DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Pancreatic cancer cells cl AsPC-1 Protein Western blotting 2020 Differential centrifugation|ExoQuick Kit Extracellular vesicles 3446 32341770 Homo sapiens DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Pancreatic cancer cells cl AsPC-1 Protein Western blotting 2020 Differential centrifugation|ExoQuick Kit Extracellular vesicles 3447 32341770 Mus musculus DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Plasma ts WT mice Protein Western blotting 2020 Differential centrifugation|ExoQuick Kit Extracellular vesicles 3448 32341770 Mus musculus DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Plasma ts Kras-active and Dusp2-null (KDC) mice Protein Western blotting 2020 Differential centrifugation|ExoQuick Kit Extracellular vesicles 3449 32341770 Homo sapiens DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Pancreatic cancer cells cl PANC-1 Protein Western blotting 2020 Differential centrifugation|ExoQuick Kit Extracellular vesicles 3450 32341770 Homo sapiens DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Pancreatic cancer cells cl PANC-1 Protein Western blotting 2020 Differential centrifugation|ExoQuick Kit Extracellular vesicles 3451 32341770 Homo sapiens DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Pancreatic cancer cells cl PANC-1 - KD Protein Western blotting 2020 Differential centrifugation|ExoQuick Kit Extracellular vesicles 3452 32341770 Homo sapiens DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Pancreatic cancer cells cl PANC-1 - KD Protein Western blotting 2020 Differential centrifugation|ExoQuick Kit Extracellular vesicles 3453 32341770 Homo sapiens DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination Pancreatic cancer cells cl PANC-1 - KD Protein Western blotting 2020 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3454 31451800 Homo sapiens Augmenting canonical Wnt signalling in therapeutically inert cells converts them into therapeutically potent exosome factories Cardiosphere-derived cells cl Primary CDCs miRNA qPCR 2019 Filtration|Centrifugal ultrafiltration Extracellular vesicles 3455 31451800 Homo sapiens Augmenting canonical Wnt signalling in therapeutically inert cells converts them into therapeutically potent exosome factories Cardiosphere-derived cells cl Immortalised CDCs miRNA qPCR 2019 Filtration|Centrifugal ultrafiltration Extracellular vesicles 3456 31451800 Homo sapiens Augmenting canonical Wnt signalling in therapeutically inert cells converts them into therapeutically potent exosome factories Fibroblasts cl Normal human dermal fibroblasts (NHDFs) miRNA qPCR 2019 Filtration|Centrifugal ultrafiltration Extracellular vesicles 3457 31451800 Homo sapiens Augmenting canonical Wnt signalling in therapeutically inert cells converts them into therapeutically potent exosome factories Fibroblasts cl Normal human dermal fibroblasts (NHDFs) miRNA qPCR 2019 Filtration|Centrifugal ultrafiltration Extracellular vesicles 3458 31451800 Homo sapiens Augmenting canonical Wnt signalling in therapeutically inert cells converts them into therapeutically potent exosome factories Primary cardiosphere-derived cells cl Low-potency CDCs miRNA qPCR 2019 Filtration|Centrifugal ultrafiltration Extracellular vesicles 3459 31451800 Homo sapiens Augmenting canonical Wnt signalling in therapeutically inert cells converts them into therapeutically potent exosome factories Primary cardiosphere-derived cells cl High-potency CDCs miRNA qPCR 2019 Filtration|Centrifugal ultrafiltration Extracellular vesicles 3460 31451800 Homo sapiens Augmenting canonical Wnt signalling in therapeutically inert cells converts them into therapeutically potent exosome factories Dermal fibroblast cells cl Normal human dermal fibroblasts (NHDFs) miRNA qPCR 2019 Filtration|Centrifugal ultrafiltration Extracellular vesicles 3461 31451800 Homo sapiens Augmenting canonical Wnt signalling in therapeutically inert cells converts them into therapeutically potent exosome factories Cardiosphere-derived cells cl Low-potency lots CDCs miRNA qPCR 2019 Filtration|Centrifugal ultrafiltration Extracellular vesicles 3462 31451800 Homo sapiens Augmenting canonical Wnt signalling in therapeutically inert cells converts them into therapeutically potent exosome factories Cardiosphere-derived cells cl Low-potency CDCs miRNA qPCR 2019 Filtration|Centrifugal ultrafiltration Extracellular vesicles 3463 31451800 Homo sapiens Augmenting canonical Wnt signalling in therapeutically inert cells converts them into therapeutically potent exosome factories Cardiosphere-derived cells cl Immortalised CDCs miRNA qPCR 2019 Filtration|Centrifugal ultrafiltration Extracellular vesicles 3464 31451800 Homo sapiens Augmenting canonical Wnt signalling in therapeutically inert cells converts them into therapeutically potent exosome factories Cardiosphere-derived cells cl Low-potency lots CDCs miRNA qPCR 2019 Filtration|Centrifugal ultrafiltration Extracellular vesicles 3465 31451800 Homo sapiens Augmenting canonical Wnt signalling in therapeutically inert cells converts them into therapeutically potent exosome factories Cardiosphere-derived cells cl Low-potency CDCs miRNA qPCR 2019 Filtration|Centrifugal ultrafiltration Extracellular vesicles 3466 31451800 Homo sapiens Augmenting canonical Wnt signalling in therapeutically inert cells converts them into therapeutically potent exosome factories Cardiosphere-derived cells cl Immortalised CDCs miRNA qPCR 2019 Filtration|Centrifugal ultrafiltration Extracellular vesicles 3467 31451800 Homo sapiens Augmenting canonical Wnt signalling in therapeutically inert cells converts them into therapeutically potent exosome factories Cardiosphere-derived cells cl Immortalised CDCs miRNA qPCR 2019 Filtration|Centrifugal ultrafiltration Extracellular vesicles 3468 35393416 Homo sapiens CHMP2A regulates tumor sensitivity to natural killer cell-mediated cytotoxicity Oral cancer cells cl Cal27 Protein Flow cytometry|Western blotting 2022 Differential centrifugation|ExoQuick Kit Extracellular vesicles 3469 35393416 Homo sapiens CHMP2A regulates tumor sensitivity to natural killer cell-mediated cytotoxicity Oral cancer cells cl Cal27 Protein Flow cytometry|Western blotting 2022 Differential centrifugation|ExoQuick Kit Extracellular vesicles 3470 31278254 Homo sapiens Small extracellular vesicles containing arginase-1 suppress T-cell responses and promote tumor growth in ovarian carcinoma Ovarian cancer cells cl CaOV-3 Protein Western blotting 2019 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3471 31278254 Homo sapiens Small extracellular vesicles containing arginase-1 suppress T-cell responses and promote tumor growth in ovarian carcinoma Ovarian cancer cells cl SK-OV-3 Protein Western blotting 2019 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3472 31278254 Homo sapiens Small extracellular vesicles containing arginase-1 suppress T-cell responses and promote tumor growth in ovarian carcinoma Ovarian cancer cells cl OvCa-14 Protein Western blotting 2019 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3473 31278254 Homo sapiens Small extracellular vesicles containing arginase-1 suppress T-cell responses and promote tumor growth in ovarian carcinoma Ovarian cancer cells cl OVP-10 Protein Western blotting 2019 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3474 31278254 Homo sapiens Small extracellular vesicles containing arginase-1 suppress T-cell responses and promote tumor growth in ovarian carcinoma Ovarian cancer cells cl MDAH2774 Protein Western blotting 2019 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3475 31278254 Homo sapiens Small extracellular vesicles containing arginase-1 suppress T-cell responses and promote tumor growth in ovarian carcinoma Cystic fluid ts Ovarian cancer patients Protein Western blotting 2019 Differential centrifugation|Size exclusion chromatography|Centrifugal ultrafiltration Extracellular vesicles 3476 31278254 Homo sapiens Small extracellular vesicles containing arginase-1 suppress T-cell responses and promote tumor growth in ovarian carcinoma Ascitic fluid ts Ovarian cancer patients Protein Western blotting|Immuno-EM 2019 Differential centrifugation|Size exclusion chromatography|Centrifugal ultrafiltration Extracellular vesicles 3477 31278254 Homo sapiens Small extracellular vesicles containing arginase-1 suppress T-cell responses and promote tumor growth in ovarian carcinoma Ovarian cancer cells cl A2780 Protein Western blotting 2019 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3478 31278254 Homo sapiens Small extracellular vesicles containing arginase-1 suppress T-cell responses and promote tumor growth in ovarian carcinoma Ascitic fluid ts Ovarian cancer patients - Patient 1 Protein Western blotting|Flow cytometry 2019 Differential centrifugation|Size exclusion chromatography|Centrifugal ultrafiltration Extracellular vesicles 3479 31278254 Homo sapiens Small extracellular vesicles containing arginase-1 suppress T-cell responses and promote tumor growth in ovarian carcinoma Ascitic fluid ts Ovarian cancer patients - Patient 2 Protein Western blotting|Flow cytometry 2019 Differential centrifugation|Size exclusion chromatography|Centrifugal ultrafiltration Extracellular vesicles 3480 31278254 Homo sapiens Small extracellular vesicles containing arginase-1 suppress T-cell responses and promote tumor growth in ovarian carcinoma Ascitic fluid ts Ovarian cancer patients - Patient 3 Protein Western blotting|Flow cytometry 2019 Differential centrifugation|Size exclusion chromatography|Centrifugal ultrafiltration Extracellular vesicles 3481 31278254 Homo sapiens Small extracellular vesicles containing arginase-1 suppress T-cell responses and promote tumor growth in ovarian carcinoma Ascitic fluid ts Ovarian cancer patients - Patient 4 Protein Western blotting|Flow cytometry 2019 Differential centrifugation|Size exclusion chromatography|Centrifugal ultrafiltration Extracellular vesicles 3482 31278254 Homo sapiens Small extracellular vesicles containing arginase-1 suppress T-cell responses and promote tumor growth in ovarian carcinoma Ascitic fluid ts Ovarian cancer patients - Patient 5 Protein Western blotting|Flow cytometry 2019 Differential centrifugation|Size exclusion chromatography|Centrifugal ultrafiltration Extracellular vesicles 3483 31278254 Homo sapiens Small extracellular vesicles containing arginase-1 suppress T-cell responses and promote tumor growth in ovarian carcinoma Ascitic fluid ts Ovarian cancer patients - Patient 6 Protein Western blotting|Flow cytometry 2019 Differential centrifugation|Size exclusion chromatography|Centrifugal ultrafiltration Extracellular vesicles 3484 31278254 Homo sapiens Small extracellular vesicles containing arginase-1 suppress T-cell responses and promote tumor growth in ovarian carcinoma Ascitic fluid ts Ovarian cancer patients - Patient 7 Protein Western blotting 2019 Differential centrifugation|Size exclusion chromatography|Centrifugal ultrafiltration Extracellular vesicles 3485 31278254 Homo sapiens Small extracellular vesicles containing arginase-1 suppress T-cell responses and promote tumor growth in ovarian carcinoma Ascitic fluid ts Ovarian cancer patients - Patient 8 Protein Western blotting 2019 Differential centrifugation|Size exclusion chromatography|Centrifugal ultrafiltration Extracellular vesicles 3486 31278254 Homo sapiens Small extracellular vesicles containing arginase-1 suppress T-cell responses and promote tumor growth in ovarian carcinoma Ascitic fluid ts Ovarian cancer patients - Patient 9 Protein Western blotting 2019 Differential centrifugation|Size exclusion chromatography|Centrifugal ultrafiltration Extracellular vesicles 3487 31278254 Homo sapiens Small extracellular vesicles containing arginase-1 suppress T-cell responses and promote tumor growth in ovarian carcinoma Ascitic fluid ts Ovarian cancer patients - Patient 10 Protein Western blotting 2019 Differential centrifugation|Size exclusion chromatography|Centrifugal ultrafiltration Extracellular vesicles 3488 31278254 Homo sapiens Small extracellular vesicles containing arginase-1 suppress T-cell responses and promote tumor growth in ovarian carcinoma Ascitic fluid ts Ovarian cancer patients - Patient 11 Protein Western blotting 2019 Differential centrifugation|Size exclusion chromatography|Centrifugal ultrafiltration Extracellular vesicles 3489 31278254 Homo sapiens Small extracellular vesicles containing arginase-1 suppress T-cell responses and promote tumor growth in ovarian carcinoma Ascitic fluid ts Ovarian cancer patients Protein Western blotting 2019 Immunoaffinity capture|Centrifugation Extracellular vesicles 3490 31278254 Mus musculus Small extracellular vesicles containing arginase-1 suppress T-cell responses and promote tumor growth in ovarian carcinoma Ovarian epithelial cells cl ID8 Protein Western blotting 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 3491 31278254 Mus musculus Small extracellular vesicles containing arginase-1 suppress T-cell responses and promote tumor growth in ovarian carcinoma Ascitic fluid cl|ts C57BL/6 inoculated with ID8-pLVX Protein Western blotting 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 3492 31278254 Mus musculus Small extracellular vesicles containing arginase-1 suppress T-cell responses and promote tumor growth in ovarian carcinoma Ascitic fluid cl|ts C57BL/6 inoculated with ID8-pLVX Protein Western blotting 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 3493 31278254 Mus musculus Small extracellular vesicles containing arginase-1 suppress T-cell responses and promote tumor growth in ovarian carcinoma Ascitic fluid cl|ts C57BL/6 inoculated with ID8-Arg1 Protein Western blotting 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 3494 31278254 Mus musculus Small extracellular vesicles containing arginase-1 suppress T-cell responses and promote tumor growth in ovarian carcinoma Ascitic fluid cl|ts C57BL/6 inoculated with ID8-Arg1 Protein Western blotting 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 3495 31160588 Homo sapiens Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2 Platelets cl Peripheral blood of healthy donors Protein Western blotting|Flow cytometry 2019 Differential centrifugation Extracellular vesicles 3496 31160588 Homo sapiens Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2 Platelets cl Peripheral blood of healthy donors Protein Flow cytometry 2019 Differential centrifugation Extracellular vesicles 3497 31160588 Homo sapiens Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2 Platelets cl Peripheral blood of healthy donors Protein Flow cytometry 2019 Differential centrifugation Extracellular vesicles 3498 31160588 Homo sapiens Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2 Platelets cl Peripheral blood of healthy donors Protein Western blotting|Flow cytometry 2019 Differential centrifugation Extracellular vesicles 3499 31160588 Homo sapiens Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2 Platelets cl Peripheral blood of healthy donors Protein Flow cytometry 2019 Differential centrifugation Extracellular vesicles 3500 31160588 Homo sapiens Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2 Platelets cl Peripheral blood of healthy donors Protein Flow cytometry 2019 Differential centrifugation Extracellular vesicles 3501 31160588 Homo sapiens Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2 Platelets cl Peripheral blood of healthy donors Protein Flow cytometry 2019 Differential centrifugation Extracellular vesicles 3502 31160588 Homo sapiens Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2 Platelets cl Peripheral blood of healthy donors Protein Flow cytometry 2019 Differential centrifugation Extracellular vesicles 3503 31160588 Homo sapiens Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2 Platelets cl Peripheral blood of healthy donors Protein Flow cytometry 2019 Differential centrifugation Extracellular vesicles 3504 31160588 Homo sapiens Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2 Platelets cl Peripheral blood of healthy donors Protein Western blotting 2019 Differential centrifugation Extracellular vesicles 3505 31160588 Homo sapiens Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2 Platelets cl Peripheral blood of healthy donors Protein Western blotting 2019 Differential centrifugation Extracellular vesicles 3506 31110292 Mus musculus The softness of tumour-cell-derived microparticles regulates their drug-delivery efficiency Liver cancer cells cl H22 - 2D culture Protein Western blotting|Mass spectrometry 2019 Differential centrifugation Microparticles 3507 31110292 Mus musculus The softness of tumour-cell-derived microparticles regulates their drug-delivery efficiency Liver cancer cells cl H22 - 3D culture Protein Western blotting|Mass spectrometry 2019 Differential centrifugation Microparticles 3508 31110292 Mus musculus The softness of tumour-cell-derived microparticles regulates their drug-delivery efficiency Liver cancer cells cl H22 - 2D culture Protein Western blotting 2019 Differential centrifugation Microparticles 3509 31110292 Mus musculus The softness of tumour-cell-derived microparticles regulates their drug-delivery efficiency Liver cancer cells cl H22 - 2D culture Protein Western blotting 2019 Differential centrifugation Microparticles 3510 31068461 Mus musculus Extracellular vesicle fibrinogen induces encephalitogenic CD8+ T cells in a mouse model of multiple sclerosis Plasma ts Whole blood - C57BL/6 Protein Western blotting|Immuno-EM 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 3511 31068461 Homo sapiens Extracellular vesicle fibrinogen induces encephalitogenic CD8+ T cells in a mouse model of multiple sclerosis Plasma ts Healthy donors Protein Western blotting|Mass spectrometry 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 3512 31068461 Homo sapiens Extracellular vesicle fibrinogen induces encephalitogenic CD8+ T cells in a mouse model of multiple sclerosis Plasma ts Relapsing-remitting multiple sclerosis patients Protein Western blotting|Mass spectrometry 2019 Differential centrifugation|Ultracentrifugation Extracellular vesicles 3513 30948809 Homo sapiens Low-cost thermophoretic profiling of extracellular-vesicle surface proteins for the early detection and classification of cancers Liver cancer cells cl HepG2 Protein Thermophoretic aptasensor (TAS) 2019 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3514 30948809 Homo sapiens Low-cost thermophoretic profiling of extracellular-vesicle surface proteins for the early detection and classification of cancers Breast cancer cells cl MDA-MB-231 Protein Thermophoretic aptasensor (TAS) 2019 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3515 30948809 Homo sapiens Low-cost thermophoretic profiling of extracellular-vesicle surface proteins for the early detection and classification of cancers Plasma ts Healthy control Protein Thermophoretic aptasensor (TAS) 2019 Filtration|Ultracentrifugation Extracellular vesicles 3516 30948809 Homo sapiens Low-cost thermophoretic profiling of extracellular-vesicle surface proteins for the early detection and classification of cancers Plasma ts Lymphoma patients Protein Thermophoretic aptasensor (TAS) 2019 Filtration|Ultracentrifugation Extracellular vesicles 3517 30948809 Homo sapiens Low-cost thermophoretic profiling of extracellular-vesicle surface proteins for the early detection and classification of cancers Plasma ts Breast cancer patients Protein Thermophoretic aptasensor (TAS) 2019 Filtration|Ultracentrifugation Extracellular vesicles 3518 30948809 Homo sapiens Low-cost thermophoretic profiling of extracellular-vesicle surface proteins for the early detection and classification of cancers Plasma ts Liver cancer patients Protein Thermophoretic aptasensor (TAS) 2019 Filtration|Ultracentrifugation Extracellular vesicles 3519 30948809 Homo sapiens Low-cost thermophoretic profiling of extracellular-vesicle surface proteins for the early detection and classification of cancers Plasma ts Lung cancer patients Protein Thermophoretic aptasensor (TAS) 2019 Filtration|Ultracentrifugation Extracellular vesicles 3520 30948809 Homo sapiens Low-cost thermophoretic profiling of extracellular-vesicle surface proteins for the early detection and classification of cancers Plasma ts Ovarian cancer patients Protein Thermophoretic aptasensor (TAS) 2019 Filtration|Ultracentrifugation Extracellular vesicles 3521 30948809 Homo sapiens Low-cost thermophoretic profiling of extracellular-vesicle surface proteins for the early detection and classification of cancers Plasma ts Prostate cancer patients Protein Thermophoretic aptasensor (TAS) 2019 Filtration|Ultracentrifugation Extracellular vesicles 3522 30948809 Homo sapiens Low-cost thermophoretic profiling of extracellular-vesicle surface proteins for the early detection and classification of cancers Plasma ts Cancer patients - Stage I Protein Thermophoretic aptasensor (TAS) 2019 Filtration|Ultracentrifugation Extracellular vesicles 3523 30948809 Homo sapiens Low-cost thermophoretic profiling of extracellular-vesicle surface proteins for the early detection and classification of cancers Plasma ts Cancer patients - Stage II Protein Thermophoretic aptasensor (TAS) 2019 Filtration|Ultracentrifugation Extracellular vesicles 3524 30948809 Homo sapiens Low-cost thermophoretic profiling of extracellular-vesicle surface proteins for the early detection and classification of cancers Plasma ts Cancer patients - Stage III Protein Thermophoretic aptasensor (TAS) 2019 Filtration|Ultracentrifugation Extracellular vesicles 3525 30948809 Homo sapiens Low-cost thermophoretic profiling of extracellular-vesicle surface proteins for the early detection and classification of cancers Plasma ts Cancer patients - Stage IV Protein Thermophoretic aptasensor (TAS) 2019 Filtration|Ultracentrifugation Extracellular vesicles 3526 30948809 Homo sapiens Low-cost thermophoretic profiling of extracellular-vesicle surface proteins for the early detection and classification of cancers Plasma ts Prostate cancer patients - without treatment Protein Thermophoretic aptasensor (TAS) 2019 Filtration|Ultracentrifugation Extracellular vesicles 3527 30948809 Homo sapiens Low-cost thermophoretic profiling of extracellular-vesicle surface proteins for the early detection and classification of cancers Plasma ts Benign disease Protein Thermophoretic aptasensor (TAS) 2019 Filtration|Ultracentrifugation Extracellular vesicles 3528 30948809 Homo sapiens Low-cost thermophoretic profiling of extracellular-vesicle surface proteins for the early detection and classification of cancers Plasma ts Prostate cancer patients - no recurrence Protein Thermophoretic aptasensor (TAS) 2019 Filtration|Ultracentrifugation Extracellular vesicles 3529 30948809 Homo sapiens Low-cost thermophoretic profiling of extracellular-vesicle surface proteins for the early detection and classification of cancers Plasma ts Prostate cancer patients - recurrence Protein Thermophoretic aptasensor (TAS) 2019 Filtration|Ultracentrifugation Extracellular vesicles 3530 30936474 Homo sapiens Extracellular vesicle-packaged HIF-1α-stabilizing lncRNA from tumour-associated macrophages regulates aerobic glycolysis of breast cancer cells Macrophage cl Monocyte-derived macrophages lncRNA Microarray|qRT-PCR 2019 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3531 30936474 Homo sapiens Extracellular vesicle-packaged HIF-1α-stabilizing lncRNA from tumour-associated macrophages regulates aerobic glycolysis of breast cancer cells Macrophage cl Polarised tumour-associated macrophages Protein|lncRNA Western blotting|Microarray|qRT-PCR 2019 Differential centrifugation|Filtration|Ultracentrifugation Extracellular vesicles 3532 30936474 Homo sapiens Extracellular vesicle-packaged HIF-1α-stabilizing lncRNA from tumour-associated macrophages regulates aerobic glycolysis of breast cancer cells Macrophage cl Polarised tumour-associated macrophages Protein Western blotting 2019 Differential centrifugation|Filtration|Ultracentrifugation|OptiPrep density gradient centrifugation Extracellular vesicles 3533 0 Homo sapiens Small RNA Sequencing of Circulating Small Extracellular Vesicle MicroRNAs in Patients with Amyotrophic Lateral Sclerosis Serum fl Serum miRNA RNA sequencing 0 ExoEasy Exosomes