EXPERIMENT ID PUBMED ID SPECIES EXPERIMENT DESCRIPTION SAMPLE SAMPLE SOURCE SAMPLE NAME IDENTIFICATIONS METHODS YEAR ISOLATION METHOD VESICLE TYPE 1 6307529 Ovis aries Fate of the transferrin receptor during maturation of sheep reticulocytes in vitro: selective externalization of the receptor. Reticulocytes ts Reticulocytes Protein Antibody based methods 1983 - Exosomes 2 3597417 Ovis aries Vesicle formation during reticulocyte maturation. Association of plasma membrane activities with released vesicles (exosomes). Reticulocytes ts Reticulocytes Protein|Lipids Enzyme assay|Antibody based methods 1987 Differential centrifugation Exosomes 3 10545503 Mus musculus Molecular characterization of dendritic cell-derived exosomes. Selective accumulation of the heat shock protein hsc73. Dendritic cells cl D1 Protein Mass spectrometry [MALDI TOF]|Western blotting 1999 Differential centrifugation|Sucrose density gradient Exosomes 4 11487543 Homo sapiens Intestinal epithelial cells secrete exosome-like vesicles. Epithelial cells cl HT29-19A|T84-DRB1*0401/CIITA (intestinal epithelial cells) Protein Mass spectrometry [MALDI TOF]|Western blotting 2001 Differential centrifugation|Sucrose density gradient Exosomes 5 11145662 Mus musculus Mast cell-dependent B and T lymphocyte activation is mediated by the secretion of immunologically active exosomes. Mast cells cl P815|MC9|Bone marrow-derived mast cells Protein Mass spectrometry [MALDI TOF]|ELISA 2001 Differential centrifugation Exosomes 6 11306949 Mus musculus Nonspecific B and T cell-stimulatory activity mediated by mast cells is associated with exosomes. Mast cells ts Bone marrow-derived mast cells Protein Western blotting 2001 - Exosomes 7 12626558 Mus musculus Mast cell-derived exosomes induce phenotypic and functional maturation of dendritic cells and elicit specific immune responses in vivo. Mast cells ts Bone marrow-derived mast cells Protein Western blotting 2003 Differential centrifugation Exosomes 8 12626558 Mus musculus Mast cell-derived exosomes induce phenotypic and functional maturation of dendritic cells and elicit specific immune responses in vivo. B cells ts B cells Protein Western blotting 2003 Differential centrifugation Exosomes 9 12626558 Mus musculus Mast cell-derived exosomes induce phenotypic and functional maturation of dendritic cells and elicit specific immune responses in vivo. Macrophages ts Macrophages Protein Western blotting 2003 Differential centrifugation Exosomes 10 11390481 Mus musculus Proteomic analysis of dendritic cell-derived exosomes: a secreted subcellular compartment distinct from apoptotic vesicles. Dendritic cells cl D1 Protein Mass spectrometry [MALDI TOF]|Mass spectrometry [QTOF]|Western blotting 2001 Differential centrifugation|Sucrose density gradient Exosomes 11 12519789 Homo sapiens Proteomic and biochemical analyses of human B cell-derived exosomes. Potential implications for their function and multivesicular body formation. B cells cl RN (HLA-DR15+) Protein|Lipids Mass spectrometry [MALDI TOF]|Mass spectrometry [QTOF]|Western blotting|Thin layer chromatography|High performance liquid chromatography 2003 Differential centrifugation|Sucrose density gradient Exosomes 12 15478216 Homo sapiens Proteomic analysis of melanoma-derived exosomes by two-dimensional polyacrylamide gel electrophoresis and mass spectrometry. Melanoma cells cl MeWo|SK-MEL-28 Protein Mass spectrometry [4700 Proteomics Analyzer]|Western blotting 2004 Filtration|Ultracentrifugation|Sucrose density gradient Exosomes 13 15326289 Homo sapiens Identification and proteomic profiling of exosomes in human urine. Urine ts Urine - Normal Protein Mass spectrometry [LCQ DECA XP]|Western blotting 2004 Ultracentrifugation Exosomes 14 16081791 Mus musculus Proteomic analysis of microglia-derived exosomes: metabolic role of the aminopeptidase CD13 in neuropeptide catabolism. Microglia cl N9 Protein Mass spectrometry [LCQ DECA XP]|Western blotting 2005 Differential centrifugation|Sucrose density gradient Exosomes 15 17486113 Mus musculus|Homo sapiens Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Mast cells cl|ts MC9|Bone marrow-derived mast cells|HMC-1 Protein|mRNA|miRNA Mass spectrometry [MALDI TOF]|Western blotting|Microarray|MicroRNA array [miRCURY LNA Array] 2007 Filtration|Ultracentrifugation|Sucrose density gradient Exosomes 16 9685355 Homo sapiens Selective enrichment of tetraspan proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B-lymphocytes. B cells cl RN (HLA-DR15+) Protein Western blotting|Immunoelectron microscopy 1998 Differential centrifugation|Sucrose density gradient Exosomes 17 11907077 Homo sapiens TCR activation of human T cells induces the production of exosomes bearing the TCR/CD3/zeta complex. T cells cl Jurkat|T cell blasts|E+ cells|MART-1+ T cell Protein Western blotting|Immunoelectron microscopy 2002 Filtration|Ultracentrifugation Exosomes 18 11907077 Homo sapiens TCR activation of human T cells induces the production of exosomes bearing the TCR/CD3/zeta complex. T cells cl Jurkat|T cell blasts Protein FACS 2002 Filtration|Ultracentrifugation Exosomes 19 16302729 Homo sapiens Purification, characterization and biological significance of tumor-derived exosomes. Breast cancer cells cl BT-474|MDA-MB-231 Protein Western blotting|FACS 2005 Differential centrifugation|Sucrose density gradient|Filtration|Immunobeads(HER2) Exosomes 20 17956143 Homo sapiens Proteomic analysis of microvesicles derived from human colorectal cancer cells. Colorectal cancer cells cl HT29 Protein Mass spectrometry [LTQ]|Western blotting 2007 Differential centrifugation|Sucrose density gradient|Diafiltration Exosomes 21 19837982 Homo sapiens Proteomic and bioinformatic analysis of immunoaffinity-purified exosomes derived from the human colon tumor cell line LIM1215. Colorectal cancer cells cl LIM1215 Protein Mass spectrometry [Orbitrap]|Western blotting 2009 Filtration|Ultracentrifugation|Sucrose density gradient Exosomes 22 15940614 Homo sapiens Human colorectal cancer cells induce T-cell death through release of proapoptotic microvesicles: role in immune escape. Colorectal cancer cells cl SW403|1869col|CRC28462 Protein Western blotting|Immunoelectron microscopy|FACS 2005 Differential centrifugation Exosomes 23 11231627 Mus musculus Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming. Mammary adenocarcinoma cl TS/A (H-2d)|P815 mastocytoma cells (H-2d) Protein Western blotting|Immunoelectron microscopy 2001 Differential centrifugation|Sucrose density gradient Exosomes 24 11231627 Homo sapiens Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming. Melanoma cells cl Fon|Mel-888 Protein Western blotting 2001 Differential centrifugation|Sucrose density gradient Exosomes 25 15111327 Homo sapiens Proteomic analysis of exosomes secreted by human mesothelioma cells. Mesothelioma cells cl PMR-MM7|PMR-MM8 Protein Mass spectrometry [MALDI TOF]|Western blotting 2004 Differential centrifugation Exosomes 26 19109410 Mus musculus Proteomic and immunologic analyses of brain tumor exosomes. Brain tumor cl SMA560vIII Protein Mass spectrometry [MALDI TOF/TOF]|Western blotting 2008 Differential centrifugation|Sucrose density gradient Exosomes 27 19109410 Homo sapiens Proteomic and immunologic analyses of brain tumor exosomes. Medulloblastoma cells cl D283MED Protein Western blotting 2008 Differential centrifugation|Sucrose density gradient Exosomes 28 19109410 Homo sapiens Proteomic and immunologic analyses of brain tumor exosomes. Glioma cells cl X43,T|D456MG|H2159MG|D54MG|D247MG Protein Western blotting 2008 Differential centrifugation|Sucrose density gradient Exosomes 29 19109410 Homo sapiens Proteomic and immunologic analyses of brain tumor exosomes. Serum ts Serum - Brain tumor Protein Western blotting 2008 Differential centrifugation|Sucrose density gradient Exosomes 30 16446100 Rattus norvegicus Exosomes are released by cultured cortical neurones. Cortical neurones ts Neurones Protein Mass spectrometry [QTOF]|Western blotting 2006 Differential centrifugation|Sucrose density gradient Exosomes 31 10572093 Homo sapiens Activated platelets release two types of membrane vesicles: microvesicles by surface shedding and exosomes derived from exocytosis of multivesicular bodies and alpha-granules. Platelets ts Platelets Protein Western blotting|FACS|Immunoelectron microscopy 1999 Differential centrifugation|Sucrose density gradient Exosomes 32 18452139 Homo sapiens Primary human keratinocytes externalize stratifin protein via exosomes. Keratinocytes ts Keratinocytes Protein Western blotting 2008 Differential centrifugation|Sucrose density gradient|Diafiltration Exosomes 33 21136642 Mus musculus Oligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons? Oligodendrocytes ts Oligodendrocytes|Oli-neu Protein Mass spectrometry [QTOF]|Western blotting|Immunoelectron microscopy 2007 Differential centrifugation|Sucrose density gradient Exosomes 34 19190083 Homo sapiens Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense. Tracheobronchial cells ts Tracheobronchial epithelial cells Protein|mRNA Mass spectrometry [QTOF]|Western blotting|Immunoelectron microscopy|FACS 2009 Differential centrifugation|Filtration|Sucrose density gradient Exosomes 35 19367702 Rattus norvegicus Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes. Hepatocytes ts Hepatocytes Protein Mass spectrometry [QTOF]|Western blotting 2008 Differential centrifugation|Filtration|Sucrose density gradient Exosomes 36 19367702 Mus musculus Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes. Hepatocytes cl MLP-29 Protein Western blotting 2008 Differential centrifugation|Filtration Exosomes 37 10878338 Homo sapiens Direct immunosuppressive effects of EBV-encoded latent membrane protein 1. B cells cl JY|B95-8 Protein Western blotting 2000 Differential centrifugation Exosomes 38 15210972 Oryctolagus cuniculus Cells release prions in association with exosomes. Epithelial cells cl RK13 (Rov epithelial cells) Protein Western blotting|Immunoelectron microscopy 2004 Differential centrifugation|Sucrose density gradient Exosomes 39 15210972 Mus musculus Cells release prions in association with exosomes. Mov neuroglial cell cl Mov neuroglial cell Protein Mass spectrometry [QSTAR]|Western blotting|Immunoelectron microscopy 2004 Differential centrifugation|Sucrose density gradient Exosomes 40 15908444 Homo sapiens Exosomal-like vesicles are present in human blood plasma. Plasma ts Plasma - Normal Protein Western blotting|FACS|Immunoelectron microscopy 2005 Differential centrifugation|Filtration|Sucrose density gradient Exosomes 41 15908444 Homo sapiens Exosomal-like vesicles are present in human blood plasma. Mast cells cl HMC-1 Protein Western blotting|FACS|Immunoelectron microscopy 2005 Differential centrifugation|Filtration|Sucrose density gradient Exosomes 42 15908444 Homo sapiens Exosomal-like vesicles are present in human blood plasma. Bone marrow cells cl PBMC Protein Western blotting 2005 Differential centrifugation|Filtration|Sucrose density gradient Exosomes 43 17076679 Homo sapiens Specific isolation of placenta-derived exosomes from the circulation of pregnant women and their immunoregulatory consequences. Plasma ts Plasma - Pregnant and not-pregnant women Protein Western blotting 2006 Size exclusion chromatography|Ultracentrifugation|Immunobeads (CD3, CD19, CD56, CD83, PLAP) Exosomes 44 19028452 Homo sapiens Proteomic profiling of human plasma exosomes identifies PPARgamma as an exosome-associated protein. Plasma ts Plasma Protein Mass spectrometry [LTQ]|Western blotting|Immunoelectron microscopy 2009 Filtration|Size exclusion chromatography|Sucrose density gradient Exosomes 45 18589210 Homo sapiens MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer. Serum ts Serum - Papillary adenocarcinoma of ovary Protein|miRNA Western blotting|MicroRNA array 2008 Ultracentrifugation|Immunobeads (EpCAM) Exosomes 46 17641064 Homo sapiens Exosomes with immune modulatory features are present in human breast milk. Breast milk ts Breast milk - colostrum Protein Mass spectrometry [QSTAR]|Western blotting|Immunoelectron microscopy|FACS 2007 Differential centrifugation|Filtration|Sucrose density gradient Exosomes 47 17641064 Homo sapiens Exosomes with immune modulatory features are present in human breast milk. B cells cl B cells Protein FACS 2007 Differential centrifugation|Filtration|Sucrose density gradient Exosomes 48 17641064 Homo sapiens Exosomes with immune modulatory features are present in human breast milk. Breast milk ts Breast milk - mature milk Protein Mass spectrometry [QSTAR]|Western blotting|Immunoelectron microscopy|FACS 2007 Differential centrifugation|Filtration|Sucrose density gradient Exosomes 49 14582906 Homo sapiens Exosomes with major histocompatibility complex class II and co-stimulatory molecules are present in human BAL fluid. Bronchoalveolar lavage fluid ts Bronchoalveolar lavage fluid Protein FACS|Immunoelectron microscopy 2003 Differential centrifugation|Immunobeads (EpCAM) Exosomes 50 14582906 Homo sapiens Exosomes with major histocompatibility complex class II and co-stimulatory molecules are present in human BAL fluid. Dendritic cells ts Monocyte-derived dendritic cells Protein FACS|Immunoelectron microscopy 2003 Differential centrifugation|Immunobeads (EpCAM) Exosomes 51 14975938 Homo sapiens Proteomic analysis of exosomes isolated from human malignant pleural effusions. Malignant pleural effusions ts Pleural Fluid - Breast cancer Protein Mass spectrometry [MALDI TOF]|Western blotting 2004 Differential centrifugation|Sucrose density gradient Exosomes 52 14975938 Homo sapiens Proteomic analysis of exosomes isolated from human malignant pleural effusions. Malignant pleural effusions ts Pleural Fluid - Lung cancer Protein Mass spectrometry [MALDI TOF]|Western blotting 2004 Differential centrifugation|Sucrose density gradient Exosomes 53 14975938 Homo sapiens Proteomic analysis of exosomes isolated from human malignant pleural effusions. Malignant pleural effusions ts Pleural Fluid - Mesothelioma Protein Mass spectrometry [MALDI TOF]|Western blotting 2004 Differential centrifugation|Sucrose density gradient Exosomes 54 14975938 Homo sapiens Proteomic analysis of exosomes isolated from human malignant pleural effusions. Malignant pleural effusions ts Pleural Fluid - Ovarian adenocarcioma Protein Western blotting 2004 Differential centrifugation|Sucrose density gradient Exosomes 55 12147373 Homo sapiens Malignant effusions and immunogenic tumour-derived exosomes. Malignant pleural effusions ts Malignant pleural effusions Protein Western blotting 2002 Differential centrifugation|Sucrose density gradient Exosomes 56 12147373 Homo sapiens Malignant effusions and immunogenic tumour-derived exosomes. Ascites ts Malignant ascites Protein Western blotting 2002 Differential centrifugation|Sucrose density gradient Exosomes 57 17700640 Homo sapiens CD24 is a marker of exosomes secreted into urine and amniotic fluid. Urine ts Urine - Normal Protein Western blotting|FACS 2007 Differential centrifugation|Sucrose density gradient Exosomes 58 17700640 Homo sapiens CD24 is a marker of exosomes secreted into urine and amniotic fluid. Amniotic fluid ts Amniotic fluid Protein Western blotting 2007 Differential centrifugation|Sucrose density gradient Exosomes 59 17700640 Mus musculus CD24 is a marker of exosomes secreted into urine and amniotic fluid. Amniotic fluid ts Amniotic fluid Protein Western blotting 2007 Differential centrifugation|Sucrose density gradient Exosomes 60 17700640 Mus musculus CD24 is a marker of exosomes secreted into urine and amniotic fluid. Urine ts Urine - Normal Protein Western blotting 2007 Differential centrifugation|Sucrose density gradient Exosomes 61 17133577 Mus musculus Association of citrullinated proteins with synovial exosomes. Synovial fluid ts Synovial fluid - osteoarthritis and reactive arthritis Protein Immunoelectron microscopy|Mass spectrometry [MALDI TOF]|Western blotting 2006 Differential centrifugation|Sucrose density gradient Exosomes 62 17133577 Mus musculus Association of citrullinated proteins with synovial exosomes. Synovial fluid ts Synovial fluid - rheumatoid arthritis Protein Immunoelectron microscopy|Mass spectrometry [MALDI TOF]|Western blotting 2006 Differential centrifugation|Sucrose density gradient Exosomes 63 19056867 Homo sapiens Large-scale proteomics and phosphoproteomics of urinary exosomes. Urine ts Urine - Normal Protein Mass spectrometry [LTQ]|Western blotting 2009 Differential centrifugation Exosomes 64 18520029 Homo sapiens Exosome-like vesicles with dipeptidyl peptidase IV in human saliva. Saliva ts Saliva Protein Western blotting|Immunoelectron microscopy|N-terminal animo acid sequencing 2008 Filtration|Diafiltration|Gel filtration Exosomes 65 19415654 Homo sapiens Proteomics of MUC1-containing lipid rafts from plasma membranes and exosomes of human breast carcinoma cells MCF-7. Breast cancer cells cl MCF-7 Protein Mass spectrometry [MALDI TOF]|Western blotting 2009 Differential centrifugation|Sucrose density gradient Exosomes 66 19199708 Homo sapiens Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT). Saliva ts Saliva Protein Mass spectrometry [LTQ]|Western blotting|Immunoelectron microscopy 2009 Differential centrifugation Exosomes 67 19619303 Homo sapiens Claudin-containing exosomes in the peripheral circulation of women with ovarian cancer. Ovarian cancer cells cl BG-1 Protein Western blotting|Immunoelectron microscopy 2009 Differential centrifugation|Sucrose density gradient Exosomes 68 19619303 Homo sapiens Claudin-containing exosomes in the peripheral circulation of women with ovarian cancer. Plasma ts Plasma - Ovarian cancer Protein Western blotting 2009 Differential centrifugation Exosomes 69 19812188 Rattus norvegicus Immature dendritic cell-derived exosomes rescue septic animals via milk fat globule epidermal growth factor VIII. Dendritic cells cl Bone marrow-derived immature dendritic cells Protein Western blotting 2009 Differential centrifugation|Sucrose density gradient Exosomes 70 19812188 Rattus norvegicus Immature dendritic cell-derived exosomes rescue septic animals via milk fat globule epidermal growth factor VIII. Dendritic cells cl Bone marrow-derived mature dendritic cells Protein Western blotting 2009 Differential centrifugation Exosomes 71 19801663 Homo sapiens Microenvironmental pH is a key factor for exosome traffic in tumor cells. Melanoma cells cl Mel1 Protein|Lipids Western blotting|Thin layer chromatography 2009 Differential centrifugation|Sucrose density gradient Exosomes 72 19801663 Homo sapiens Microenvironmental pH is a key factor for exosome traffic in tumor cells. Melanoma cells cl Me665/1 Protein|Lipids Western blotting|Thin layer chromatography 2009 Differential centrifugation Exosomes 73 18494037 Mus musculus Difference gel electrophoresis analysis of Ras-transformed fibroblast cell-derived exosomes. Embryonic fibroblast cells cl NIH3T3 Protein Mass spectrometry [LCQ DECA]|Western blotting 2008 Differential centrifugation Exosomes 74 19381331 Homo sapiens High levels of exosomes expressing CD63 and caveolin-1 in plasma of melanoma patients. Melanoma cells cl Me501 Protein Western blotting|ELISA|FACS 2009 Differential centrifugation Exosomes 75 19381331 Homo sapiens High levels of exosomes expressing CD63 and caveolin-1 in plasma of melanoma patients. Plasma ts Plasma - melanoma Protein Western blotting|ELISA|FACS 2009 Differential centrifugation Exosomes 76 20224111 Homo sapiens Proteomics analysis of bladder cancer exosomes. Bladder cancer cells cl HT1376 Protein Mass spectrometry [MALDI TOF/TOF]|Western blotting|FACS 2010 Differential centrifugation|Sucrose density gradient Exosomes 77 20224111 Homo sapiens Proteomics analysis of bladder cancer exosomes. Urine ts Urine - Normal Protein FACS 2010 Differential centrifugation|Sucrose density gradient Exosomes 78 20224111 Homo sapiens Proteomics analysis of bladder cancer exosomes. Urine ts Urine - Prostate cancer Protein FACS 2010 Differential centrifugation|Sucrose density gradient Exosomes 79 20458337 Homo sapiens MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 1 B cells cl RN (HLA-DR15) Protein Mass spectrometry [FT-ICR]|Western blotting 2010 Differential centrifugation|Sucrose density gradient|Immunobeads (MHC Class II) Exosomes 80 20458337 Homo sapiens MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis -Sample 2 B cells cl RN (HLA-DR15) Protein Mass spectrometry [FT-ICR]|Western blotting 2010 Differential centrifugation|Sucrose density gradient|Immunobeads (MHC Class II) Exosomes 81 20458337 Homo sapiens MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 3 B cells cl RN (HLA-DR15) Protein Mass spectrometry [FT-ICR]|Western blotting 2010 Differential centrifugation|Sucrose density gradient|Immunobeads (MHC Class II) Exosomes 82 20949044 Homo sapiens Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line Stomach cancer cells cl AZ-521 Protein|miRNA Western blotting|RT-PCR|Human miRNA Microarray Kit 2010 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 83 20949044 Homo sapiens Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line Lung cancer cells cl SBC-3 Protein|miRNA Western blotting|RT-PCR|Human miRNA Microarray Kit 2010 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 84 20949044 Homo sapiens Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line Lung cancer cells cl DMS-53 miRNA Human miRNA Microarray Kit|RT-PCR 2010 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 85 20949044 Homo sapiens Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line Lung cancer cells cl NCI-H69 miRNA Human miRNA Microarray Kit|RT-PCR 2010 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 86 20949044 Homo sapiens Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line Colorectal cancer cells cl SW480 miRNA Human miRNA Microarray Kit|RT-PCR 2010 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 87 20949044 Homo sapiens Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line Colorectal cancer cells cl SW620 miRNA RT-PCR 2010 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 88 20949044 Homo sapiens Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line Stomach cancer cells cl AZ-P7a Protein|miRNA Immunoelectron microscopy|Western blotting|RT-PCR|Human miRNA Microarray Kit 2010 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 89 20424270 Rattus norvegicus Exosomes account for vesicle-mediated transcellular transport of activatable phospholipases and prostaglandins. Basophilic leukemia cells cl RBL-2H3 Protein|Lipids Western blotting|Gas chromatography|Thin layer chromatography|Mass spectrometry [Qstar XL]|FACS 2010 Differential centrifugation|Sucrose density gradient Exosomes 90 21828046 Rattus norvegicus The proteo-lipidic composition of exosomes changes during reticulocyte maturation. Reticulocytes ts Reticulocytes - D2 Rep 1 Protein|Lipids Mass spectrometry [QSTAR]|Mass spectrometry [Orbitrap]|Western blotting 2011 Differential centrifugation|Ultracentrifugation|Sucrose density gradient Exosomes 91 21252909 Homo sapiens Diacylglycerol kinase a regulates the formation and polarisation of mature multivesicular bodies involved in the secretion of Fas ligand-containing exosomes in T lymphocytes T cells cl J-HM1-2.2 Protein|Lipids Western blotting|FACS|Immunofluorescent microscopy 2011 Differential centrifugation|Ultracentrifugation Exosomes 92 20124479 Rattus norvegicus Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation. Pancreatic adenocarcinoma cells cl AS Protein|mRNA RT-PCR|Western blotting|RatRef-12 Microarray|FACS|Mass spectrometry [MALDI TOF] 2010 Differential centrifugation|Sucrose density gradient Exosomes 93 20124479 Rattus norvegicus Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation. Pancreatic adenocarcinoma cells cl AS-Tspan8 Protein|mRNA RT-PCR|Western blotting 2010 Differential centrifugation|Sucrose density gradient Exosomes 94 21828046 Rattus norvegicus The proteo-lipidic composition of exosomes changes during reticulocyte maturation. Reticulocytes ts Reticulocytes - D4 Rep 1 Protein|Lipids Mass spectrometry [QSTAR]|Mass spectrometry [Orbitrap]|Western blotting 2011 Differential centrifugation|Ultracentrifugation|Sucrose density gradient Exosomes 95 21828046 Rattus norvegicus The proteo-lipidic composition of exosomes changes during reticulocyte maturation. Reticulocytes ts Reticulocytes - D7 Rep 1 Protein|Lipids Mass spectrometry [QSTAR]|Mass spectrometry [Orbitrap]|Western blotting 2011 Differential centrifugation|Ultracentrifugation|Sucrose density gradient Exosomes 96 21828046 Rattus norvegicus The proteo-lipidic composition of exosomes changes during reticulocyte maturation. Reticulocytes ts Reticulocytes - D2 Rep 2 Protein|Lipids Mass spectrometry [QSTAR]|Mass spectrometry [Orbitrap]|Western blotting 2011 Differential centrifugation|Ultracentrifugation|Sucrose density gradient Exosomes 97 21828046 Rattus norvegicus The proteo-lipidic composition of exosomes changes during reticulocyte maturation. Reticulocytes ts Reticulocytes - D4 Rep 2 Protein|Lipids Mass spectrometry [QSTAR]|Mass spectrometry [Orbitrap]|Western blotting 2011 Differential centrifugation|Ultracentrifugation|Sucrose density gradient Exosomes 98 21828046 Rattus norvegicus The proteo-lipidic composition of exosomes changes during reticulocyte maturation. Reticulocytes ts Reticulocytes - D7 Rep 2 Protein|Lipids Mass spectrometry [QSTAR]|Mass spectrometry [Orbitrap]|Western blotting 2011 Differential centrifugation|Ultracentrifugation|Sucrose density gradient Exosomes 99 21828046 Rattus norvegicus The proteo-lipidic composition of exosomes changes during reticulocyte maturation. Reticulocytes ts Reticulocytes - D2 Rep 3 Protein|Lipids Mass spectrometry [QSTAR]|Mass spectrometry [Orbitrap]|Western blotting 2011 Differential centrifugation|Ultracentrifugation|Sucrose density gradient Exosomes 100 21828046 Rattus norvegicus The proteo-lipidic composition of exosomes changes during reticulocyte maturation. Reticulocytes ts Reticulocytes - D4 Rep 3 Protein|Lipids Mass spectrometry [QSTAR]|Mass spectrometry [Orbitrap]|Western blotting 2011 Differential centrifugation|Ultracentrifugation|Sucrose density gradient Exosomes 101 21828046 Rattus norvegicus The proteo-lipidic composition of exosomes changes during reticulocyte maturation. Reticulocytes ts Reticulocytes - D7 Rep 3 Protein|Lipids Mass spectrometry [QSTAR]|Mass spectrometry [Orbitrap]|Western blotting 2011 Differential centrifugation|Ultracentrifugation|Sucrose density gradient Exosomes 102 21082674 Homo sapiens Comprehensive analysis of low-abundance proteins in human urinary exosomes using peptide ligand library technology, peptide OFFGEL fractionation and nanoHPLC-chip-MS/MS. Urine ts Urine - Normal Protein Mass spectrometry|Western blotting|Immunoelectron microscopy 2010 Differential centrifugation|Ultracentrifugation Exosomes 103 21763319 Homo sapiens Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells. Pancreatic adenocarcinoma cells cl Panc1 Protein Mass spectrometry [Orbitrap]|Western blotting 2011 Differential centrifugation|Filtration|Ultrafiltration|Ultracentrifugation Exosomes 104 21763319 Homo sapiens Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells. Pancreatic adenocarcinoma cells cl BxPC3 Protein Western blotting 2011 Differential centrifugation|Filtration|Ultrafiltration|Ultracentrifugation Exosomes 105 21763319 Homo sapiens Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells. Pancreatic adenocarcinoma cells cl Paca44 Protein Western blotting 2011 Differential centrifugation|Filtration|Ultrafiltration|Ultracentrifugation Exosomes 106 21763319 Homo sapiens Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells. Pancreatic adenocarcinoma cells cl MiaPaca2 Protein Western blotting 2011 Differential centrifugation|Filtration|Ultrafiltration|Ultracentrifugation Exosomes 107 21763319 Homo sapiens Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells. Pancreatic adenocarcinoma cells cl A818-4 Protein Western blotting 2011 Differential centrifugation|Filtration|Ultrafiltration|Ultracentrifugation Exosomes 108 21601258 Homo sapiens Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage. Ascites ts Malignant ascites - ovarian cancer Protein|miRNA Western blotting|Immunoelectron microscopy 2011 Differential centrifugation|Sucrose density gradient|Immunobeads (EpCAM, CD24) Exosomes 109 21601258 Homo sapiens Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage. Malignant pleural effusions ts Pleural effusions - breast cancer Protein|miRNA Western blotting 2011 Differential centrifugation|Sucrose density gradient|Immunobeads (EpCAM) Exosomes 110 21601258 Homo sapiens Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage. Ascites ts Ascites - liver cirrhosis Protein|miRNA Western blotting|Immunoelectron microscopy 2011 Differential centrifugation|Sucrose density gradient Exosomes 111 21601258 Homo sapiens Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage. Serum ts Serum - breast cancer Protein|miRNA Western blotting 2011 Differential centrifugation|Sucrose density gradient|Immunobeads (CD24) Exosomes 112 21601258 Homo sapiens Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage. Serum ts Serum - Normal Protein|miRNA Western blotting 2011 Differential centrifugation|Sucrose density gradient Exosomes 113 21557262 Homo sapiens Proteomic identification of exosomal LRG1: A potential urinary biomarker for detecting NSCLC. Urine ts Urine - Normal Protein Mass spectrometry|Western blotting 2011 Differential centrifugation|Ultracentrifugation Exosomes 114 21557262 Homo sapiens Proteomic identification of exosomal LRG1: A potential urinary biomarker for detecting NSCLC. Urine ts Urine - Lung cancer Protein Mass spectrometry|Western blotting 2011 Differential centrifugation|Ultracentrifugation Exosomes 115 21505438 Homo sapiens Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells. T cells cl J77 Protein|miRNA Mass spectrometry|Microarray 2011 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 116 21505438 Homo sapiens Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells. B cells cl Raji Protein|miRNA Mass spectrometry|Microarray 2011 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 117 21505438 Homo sapiens Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells. Dendritic cells ts Dendritic cells Protein|miRNA Mass spectrometry|Microarray 2011 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 118 21362503 Homo sapiens Protein profile of exosomes from trabecular meshwork cells. Tabecular meshwork cells ts Tabecular meshwork cells Protein Mass spectrometry [LTQ]|Western blotting 2011 Differential centrifugation|Sucrose density gradient Exosomes 119 21362503 Homo sapiens Protein profile of exosomes from trabecular meshwork cells. Urine ts Urine - Normal Protein Mass spectrometry [LTQ]|Western blotting 2011 Differential centrifugation|Sucrose density gradient Exosomes 120 21362503 Homo sapiens Protein profile of exosomes from trabecular meshwork cells. Aqueous humor ts Aqueous humor - Normal Protein Western blotting 2011 Differential centrifugation|Sucrose density gradient Exosomes 121 21276792 Homo sapiens Morphologic and proteomic characterization of exosomes released by cultured extravillous trophoblast cells. Trophoblast cells cl Sw71 Protein Mass spectrometry [Orbitrap]|Western blotting 2011 Differential centrifugation|Ultrafiltration|Ultracentrifugation|Sucrose density gradient Exosomes 122 21235781 Homo sapiens Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages. Saliva ts Saliva - Normal Protein FACS|Immunoelectron microscopy|Western blotting 2011 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 123 21235781 Homo sapiens Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages. Plasma ts Plasma - Normal Protein FACS|Immunoelectron microscopy|Western blotting 2011 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 124 21235781 Homo sapiens Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages. Breast milk ts Breast milk - normal Protein FACS|Immunoelectron microscopy|Western blotting 2011 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 125 21059916 Homo sapiens Human tumor virus utilizes exosomes for intercellular communication. Nasopharyngeal carcinoma cells cl C666 Protein Western blotting 2010 Differential centrifugation Exosomes 126 0 Homo sapiens Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy? Mesenchymal stem cells cl huES9.E1 Protein Western blotting|Antibody array|Mass spectrometry 2011 HPLC Exosomes 127 21828046 Rattus norvegicus Proteolipidic Composition of Exosomes Changes during Reticulocyte Maturation Reticulocytes ts Reticulocytes Protein|Lipids Gas-liquid chromatography|High performance thin layer chromatography 2011 Differential centrifugation|Ultracentrifugation|Sucrose density gradient Exosomes 128 14965343 Homo sapiens Mast cell- and dendritic cell-derived exosomes display a specific lipid composition and an unusual membrane organization Dendritic cells ts Bone marrow - Dendritic cells Lipids High performance liquid chromatography|Gas chromatography 2004 Differential centrifugation|Ultracentrifugation Exosomes 129 14965343 Rattus norvegicus Mast cell- and dendritic cell-derived exosomes display a specific lipid composition and an unusual membrane organization Tumoral mast cells cl RBL-2H3 Lipids High performance liquid chromatography|Gas chromatography 2004 Differential centrifugation|Ultracentrifugation Exosomes 130 18309083 Mus musculus Ceramide triggers budding of exosome vesicles into multivesicular endosomes Oligodendrocytes cl Oli-neu cells Protein|Lipids Western blotting|Mass spectrometry[QTOF] 2008 Differential centrifugation|Sucrose density gradient Exosomes 131 19188015 Homo sapiens Systemic presence and tumor-growth promoting effect of ovarian carcinoma released exosomes Ascites ts Malignant ascites - Ovarian cancer Protein|Lipids Cytofluorographic analysis|Annexin V-FITC|Western blotting|FACS 2009 Differential centrifugation|Sucrose density gradient Exosomes 132 19188015 Homo sapiens Systemic presence and tumor-growth promoting effect of ovarian carcinoma released exosomes Ovarian cancer cells cl OVMz Protein|Lipids Cytofluorographic analysis|Annexin V-FITC|FACS 2009 Differential centrifugation|Sucrose density gradient Exosomes 133 19188015 Homo sapiens Systemic presence and tumor-growth promoting effect of ovarian carcinoma released exosomes Ovarian cancer cells cl SKOV3ip Protein|Lipids Cytofluorographic analysis|Annexin V-FITC|FACS 2009 Differential centrifugation|Sucrose density gradient Exosomes 134 15304316 Rattus norvegicus PLD2 is enriched on exosomes and its activity is correlated to the release of exosomes Basophilic leukemia cells cl RBL-2H3 Protein|Lipids Western blotting|FACS 2004 Differential centrifugation Exosomes 135 2777884 Cavia porcellus Asymmetric Distribution of Phospholipids in the Membrane of Vesicles Released During In Vitro Maturation of Guinea Pig Reticulocytes: Evidence Precluding a Role for "Aminophospholipid Translocase Reticulocytes ts Reticulocytes - Normal Proteins|Lipids Immunoelectron microscopy|Thin layer chromatography|Western blotting 1989 Differential centrifugation|Ultracentrifugation Exosomes 136 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells cl PC3 - Rep 2 Protein Mass spectrometry [QTOF] 2012 Sucrose density gradient Exosomes 137 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells cl PC3 - Rep 3 Protein Mass spectrometry [QTOF] 2012 Sucrose density gradient Exosomes 138 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells cl DU145 - Rep 2 Protein Mass spectrometry [QTOF] 2012 Sucrose density gradient Exosomes 139 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells cl DU145 - Rep 3 Protein Mass spectrometry [QTOF] 2012 Sucrose density gradient Exosomes 140 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells cl VCaP - Rep 2 Protein Mass spectrometry [QTOF] 2012 Sucrose density gradient Exosomes 141 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells cl VCaP - Rep 3 Protein Mass spectrometry [QTOF] 2012 Sucrose density gradient Exosomes 142 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells cl LNCaP - Rep 2 Protein Mass spectrometry [QTOF] 2012 Sucrose density gradient Exosomes 143 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells cl LNCaP - Rep 3 Protein Mass spectrometry [QTOF] 2012 Sucrose density gradient Exosomes 144 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells cl C4-2 - Rep 2 Protein Mass spectrometry [QTOF] 2012 Sucrose density gradient Exosomes 145 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells cl C4-2 - Rep 3 Protein Mass spectrometry [QTOF] 2012 Sucrose density gradient Exosomes 146 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells cl RWPE - Rep 2 Protein Mass spectrometry [QTOF] 2012 Sucrose density gradient Exosomes 151 22075275 Homo sapiens Methodology for isolation, identification and characterization of microvesicles in peripheral blood Plasma ts Plasma - Normal Protein FACS 2011 Differential centrifugation|Filtration|Ultracentrifugation Microvesicles 152 22064971 Homo sapiens Oxidized low-density lipoprotein-dependent platelet-derived microvesicles trigger procoagulant effects and amplify oxidative stress Platelets ts Platelets Protein FACS|ELISA 2011 Differential centrifugation Microvesicles 153 22022598 Homo sapiens Syncytiotrophoblast microvesicles released from pre-eclampsia placentae exhibit increased tissue factor activity Placenta ts Placenta Protein FACS 2011 Differential centrifugation Microvesicles 154 21966536 Mus musculus Leukocyte- and platelet-derived microvesicle interactions following in vitro and in vivo activation of toll-like receptor 4 by lipopolysaccharide Plasma ts Plasma - Normal Protein FACS 2011 Differential centrifugation|Filtration Microvesicles 155 21939504 Homo sapiens Microvesicles secreted by macrophages shuttle invasion-potentiating microRNAs into breast cancer cells Macrophages ts Macrophages - Unactivated miRNA RT-PCR 2011 Differential centrifugation|Filtration|Ultracentrifugation Microvesicles 156 21939504 Homo sapiens Microvesicles secreted by macrophages shuttle invasion-potentiating microRNAs into breast cancer cells Macrophages ts Macrophages - IL-4 activated miRNA RT-PCR 2011 Differential centrifugation|Filtration|Ultracentrifugation Microvesicles 157 21630462 Homo sapiens Proteomic analysis of microvesicles derived from human colorectal cancer ascites Ascites ts Malignant ascites - Colorectal cancer patient 1 Protein Mass spectrometry [LTQ] 2011 Differential centrifugation|Sucrose density gradient|OptiPrep density gradient Microvesicles 158 21630462 Homo sapiens Proteomic analysis of microvesicles derived from human colorectal cancer ascites Ascites ts Malignant ascites - Colorectal cancer patient 2 Protein Mass spectrometry [LTQ] 2011 Differential centrifugation|Sucrose density gradient|OptiPrep density gradient Microvesicles 159 21630462 Homo sapiens Proteomic analysis of microvesicles derived from human colorectal cancer ascites Ascites ts Malignant ascites - Colorectal cancer patient 3 Protein Mass spectrometry [LTQ] 2011 Differential centrifugation|Sucrose density gradient|OptiPrep density gradient Microvesicles 160 21630462 Homo sapiens Proteomic analysis of microvesicles derived from human colorectal cancer ascites Ascites ts Malignant ascites - Colorectal cancer Protein Western blotting 2011 Differential centrifugation|Sucrose density gradient|OptiPrep density gradient Microvesicles 161 21901833 Drosophila melanogaster Proteomics analyses of microvesicles released by Drosophila Kc167 and S2 cells Hematocytes cl Kc167 Protein|PTM Ubiquitination Western blotting|Mass spectrometry [HCT ETD II iontrap] 2011 Differential centrifugation|Sucrose density gradient|Ultracentrifugation Microvesicles 162 21901833 Drosophila melanogaster Proteomics analyses of microvesicles released by Drosophila Kc167 and S2 cells Hematocytes cl S2 Protein|PTM Ubiquitination Western blotting|Mass spectrometry [HCT ETD II iontrap] 2011 Differential centrifugation|Sucrose density gradient|Ultracentrifugation Microvesicles 163 21901833 Drosophila melanogaster Proteomics analyses of microvesicles released by Drosophila Kc167 and S2 cells Hematocytes cl S2-tub-wg Protein Western blotting|Immunoelectron microscopy 2011 Differential centrifugation|Sucrose density gradient|Ultracentrifugation Microvesicles 164 21864488 Homo sapiens Marrow cell genetic phenotype change induced by human lung cancer cells Lung cancer cells ts Lung cancer cells - patient 1 mRNA RT-PCR 2011 Differential centrifugation|Ultracentrifugation Microvesicles 165 21864488 Homo sapiens Marrow cell genetic phenotype change induced by human lung cancer cells Lung cancer cells ts Lung cancer cells - patient 2 mRNA RT-PCR 2011 Differential centrifugation|Ultracentrifugation Microvesicles 166 21864488 Homo sapiens Marrow cell genetic phenotype change induced by human lung cancer cells Lung cancer cells ts Lung cancer cells - patient 3 mRNA RT-PCR 2011 Differential centrifugation|Ultracentrifugation Microvesicles 167 21859146 Homo sapiens Identification of a conserved glycan signature for microvesicles T cells cl Jurkat Protein Western blotting 2011 Differential centrifugation|Filtration|Ultracentrifugation Microvesicles 168 21859146 Homo sapiens Identification of a conserved glycan signature for microvesicles T cells cl SupT1 Protein Western blotting 2011 Differential centrifugation|Filtration|Ultracentrifugation Microvesicles 169 21859146 Homo sapiens Identification of a conserved glycan signature for microvesicles T cells cl H9 Protein Western blotting 2011 Differential centrifugation|Filtration|Ultracentrifugation Microvesicles 170 21859146 Homo sapiens Identification of a conserved glycan signature for microvesicles Colorectal cancer cells cl HCT-15 Protein Western blotting 2011 Differential centrifugation|Filtration|Ultracentrifugation Microvesicles 171 21859146 Homo sapiens Identification of a conserved glycan signature for microvesicles Colorectal cancer cells cl HT-29 Protein Western blotting 2011 Differential centrifugation|Filtration|Ultracentrifugation Microvesicles 172 21859146 Homo sapiens Identification of a conserved glycan signature for microvesicles Melanoma cells cl SkMel-5 Protein Western blotting 2011 Differential centrifugation|Filtration|Ultracentrifugation Microvesicles 173 21859146 Homo sapiens Identification of a conserved glycan signature for microvesicles Breast milk ts Breast milk - normal Protein Western blotting 2011 Differential centrifugation|Filtration|Ultracentrifugation Microvesicles 174 21842121 Mus musculus Oligodendroglioma cells shed microvesicles which contain TRAIL as well as molecular chaperones and induce cell death in astrocytes Oligodendrocytes cl G26/24 Protein Western blotting 2011 Differential centrifugation Microvesicles 175 19002258 Homo sapiens Detection of microRNA Expression in Human Peripheral Blood Microvesicles Plasma ts Plasma - Normal miRNA RT-PCR 2008 Differential centrifugation Microvesicles 176 21788507 Homo sapiens Hypoxia triggers a proangiogenic pathway involving cancer cell microvesicles and PAR-2-mediated heparin-binding EGF signaling in endothelial cells Glioblastoma cells cl U87-MG Protein Immunoelectron microscopy|Western blotting 2011 Differential centrifugation Microvesicles 177 19567368 Homo sapiens Proteomics characterization of cell membrane blebs in human retinal pigment epithelium cells Epithelial cells cl ARPE-19 (Retinal epithelial cells) Protein Western blotting|Mass spectrometry [LTQ-FT Ultra] 2009 Differential centrifugation Membrane blebs 178 20686450 Homo sapiens Comparison of three methods for isolation of urinary microvesicles to identify biomarkers of nephrotic syndrome Urine ts Urine - NM UF Protein Western blotting|Mass spectrometry [MALDI TOF] 2010 Differential centrifugation|Ultrafiltration Microvesicles 179 20686450 Homo sapiens Comparison of three methods for isolation of urinary microvesicles to identify biomarkers of nephrotic syndrome Urine ts Urine - UC Protein Western blotting|Mass spectrometry [MALDI TOF] 2010 Differential centrifugation|Ultracentrifugation Microvesicles 180 20686450 Homo sapiens Comparison of three methods for isolation of urinary microvesicles to identify biomarkers of nephrotic syndrome Urine ts Urine - SEC Protein Western blotting|Mass spectrometry [MALDI TOF] 2010 Differential centrifugation|Ultracentrifugation|Size exclusion chromatography|Filtration Microvesicles 181 20668554 Homo sapiens Microvesicles derived from adult human bone marrow and tissue specific mesenchymal stem cells shuttle selected pattern of miRNAs Mesenchymal stem cells ts Mesenchymal stem cells - Normal Protein|miRNA Western blotting|RT-PCR|Immunogold|Immunoelectron microscopy 2010 Differential centrifugation|Ultracentrifugation Microvesicles 182 20668554 Homo sapiens Microvesicles derived from adult human bone marrow and tissue specific mesenchymal stem cells shuttle selected pattern of miRNAs Liver stem cells ts Liver stem cells - Normal miRNA Western blotting|RT-PCR|Immunogold|Immunoelectron microscopy 2010 Differential centrifugation|Ultracentrifugation Microvesicles 183 21741384 Homo sapiens A filtration-based protocol to isolate human plasma membrane-derived vesicles and exosomes from blood plasma Plasma ts Plasma - Normal Protein FACS|ELISA 2011 Differential centrifugation|Filtration Microvesicles 184 21672581 Rattus norvegicus Oxygen-glucose deprivation increases the enzymatic activity and the microvesicle-mediated release of ectonucleotidases in the cells composing the blood-brain barrier Astrocytes ts Astrocytes - Normal Protein Immunoelectron microscopy 2011 Differential centrifugation Microvesicles 185 22116803 Equus caballus Cell-Secreted Vesicles in Equine Ovarian Follicular Fluid Contain miRNAs and Proteins: A Possible New Form of Cell Communication Within the Ovarian Follicle Follicular fluid ts Follicular fluid - Ovarian - Young mare Protein|miRNA Western blotting|RT-PCR|Mass spectrometry [LTQ] 2011 Differential centrifugation|Exoquick Exosomes 186 22116803 Equus caballus Cell-Secreted Vesicles in Equine Ovarian Follicular Fluid Contain miRNAs and Proteins: A Possible New Form of Cell Communication Within the Ovarian Follicle Follicular fluid ts Follicular fluid - Ovarian Protein|miRNA RT-PCR|FACS 2011 Differential centrifugation|Ultracentrifugation Microvesicles 187 22116803 Equus caballus Cell-Secreted Vesicles in Equine Ovarian Follicular Fluid Contain miRNAs and Proteins: A Possible New Form of Cell Communication Within the Ovarian Follicle Serum ts Serum - Normal Protein FACS 2011 Differential centrifugation|Exoquick Exosomes 189 21741384 Homo sapiens A filtration-based protocol to isolate human plasma membrane-derived vesicles and exosomes from blood plasma Plasma ts Plasma - Normal Protein FACS|ELISA 2011 Differential centrifugation|Filtration Exosomes 190 22116803 Equus caballus Cell-Secreted Vesicles in Equine Ovarian Follicular Fluid Contain miRNAs and Proteins: A Possible New Form of Cell Communication Within the Ovarian Follicle Follicular fluid ts Follicular fluid - Ovarian - Old mare miRNA RT-PCR 2011 Differential centrifugation|Exoquick Exosomes 191 21635979 Mus musculus Proteomic characterization of thymocyte-derived microvesicles and apoptotic bodies in BALB/c mice Thymus ts Thymocytes - Normal Protein Western blotting|FACS|Mass spectrometry [QTOF] 2011 Differential centrifugation|Filtration Microvesicles 192 21635979 Mus musculus Proteomic characterization of thymocyte-derived microvesicles and apoptotic bodies in BALB/c mice Thymus ts Thymocytes - Normal Protein Western blotting|FACS|Mass spectrometry [QTOF] 2011 Differential centrifugation|Filtration Apoptotic bodies 193 21575145 Homo sapiens Microvesicle-mediated release of soluble LH/hCG receptor (LHCGR) from transfected cells and placenta explants Placenta ts Placenta - Normal Protein Western blotting 2011 Differential centrifugation|Ultracentrifugation Microvesicles 195 21668449 Mus musculus SV31 is a Zn2+-binding synaptic vesicle protein PC12 cells ts PC12 cells Protein Western blotting 2011 Differential centrifugation|Sucrose density gradient Large dense core vesicles 196 21668449 Mus musculus SV31 is a Zn2+-binding synaptic vesicle protein PC12 cells ts PC12 cells - Transfected Protein Western blotting 2011 Differential centrifugation|Sucrose density gradient Large dense core vesicles 197 21616097 Homo sapiens Release of podocalyxin into the extracellular space. Role of metalloproteinases Testicular cancer cells cl Tera-1 Protein Western blotting 2011 Differential centrifugation Microvesicles 198 21555566 Homo sapiens Multiple recognition assay reveals prostasomes as promising plasma biomarkers for prostate cancer Plasma ts Plasma - Prostate cancer Protein Proximity ligation assay 2011 Differential centrifugation|Ultracentrifugation|Gel chromatography Microvesicles 199 21609964 Homo sapiens Characterization of extracellular circulating microRNA Plasma ts Plasma - Normal Protein Western blotting 2011 Differential centrifugation|Filtration Exosomes 200 21606166 Homo sapiens Blast-derived microvesicles in sera from patients with acute myeloid leukemia suppress natural killer cell function via membrane-associated transforming growth factor-beta1 Serum ts Serum - Normal Protein Western blotting|FACS 2011 Size exclusion chromatography|Ultracentrifugation Microvesicles 201 21606166 Homo sapiens Blast-derived microvesicles in sera from patients with acute myeloid leukemia suppress natural killer cell function via membrane-associated transforming growth factor-beta2 Serum ts Serum - Acute myeloid leukemia Protein Western blotting|FACS 2011 Size exclusion chromatography|Ultracentrifugation Microvesicles 202 21601655 Homo sapiens Sizing and phenotyping of cellular vesicles using Nanoparticle Tracking Analysis Placenta ts Placenta - Normal Protein FACS|Immunoelectron microscopy 2011 Differential centrifugation|Ultracentrifugation Microvesicles 203 19011622 Homo sapiens Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers Glioblastoma cells ts Glioblastoma cells Protein|miRNA|mRNA RT-PCR|Antibody array|Microarray 2008 Differential centrifugation|Ultracentrifugation|Filtration Microvesicles 204 19011622 Homo sapiens Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers Serum ts Serum - Normal mRNA|miRNA RT-PCR 2008 Differential centrifugation|Ultracentrifugation|Filtration Microvesicles 205 19011622 Homo sapiens Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers Serum ts Serum - Glioblastoma mRNA|miRNA RT-PCR 2008 Differential centrifugation|Ultracentrifugation|Filtration Microvesicles 206 21435393 Rattus norvegicus Microvesicles released from rat adipocytes and harboring glycosylphosphatidylinositol-anchored proteins transfer RNA stimulating lipid synthesis Adipocytes ts Adipocytes - Large mRNA|miRNA RT-PCR 2011 Differential centrifugation|Immunobeads (Gce1/CD73) Microvesicles 207 21435393 Rattus norvegicus Microvesicles released from rat adipocytes and harboring glycosylphosphatidylinositol-anchored proteins transfer RNA stimulating lipid synthesis Adipocytes ts Stromal vascular cells - Differentiated adipocytes mRNA|miRNA RT-PCR 2011 Differential centrifugation|Sucrose density gradient|Size exclusion chromatography Microvesicles 208 21435393 Rattus norvegicus Microvesicles released from rat adipocytes and harboring glycosylphosphatidylinositol-anchored proteins transfer RNA stimulating lipid synthesis Serum ts Serum - Normal mRNA|miRNA RT-PCR 2011 Differential centrifugation|Sucrose density gradient|Immunobeads (Gce1/CD73) Microvesicles 209 21435393 Rattus norvegicus Microvesicles released from rat adipocytes and harboring glycosylphosphatidylinositol-anchored proteins transfer RNA stimulating lipid synthesis Adipocytes ts Adipocytes - Small mRNA|miRNA RT-PCR 2011 Differential centrifugation|Immunobeads (Gce1/CD73) Microvesicles 210 21368175 Homo sapiens Cancer cell-derived microvesicles induce transformation by transferring tissue transglutaminase and fibronectin to recipient cells Breast cancer cells cl MDA-MB-231 Protein Western blotting|Immunofluorescent microscopy|Scanning electron microscopy|Mass spectrometry [4000 Q Trap] 2011 Differential centrifugation|Filtration Microvesicles 211 21368175 Homo sapiens Cancer cell-derived microvesicles induce transformation by transferring tissue transglutaminase and fibronectin to recipient cells Glioma cells cl U87 Protein Western blotting|Mass spectrometry [4000 Q Trap] 2011 Differential centrifugation|Filtration Microvesicles 212 21372807 Rattus norvegicus Upregulation of lipid synthesis in small rat adipocytes by microvesicle-associated CD73 from large adipocytes Adipocytes ts Adipocytes - Large Protein Western blotting 2011 Differential centrifugation Microvesicles 213 21372807 Rattus norvegicus Upregulation of lipid synthesis in small rat adipocytes by microvesicle-associated CD73 from large adipocytes Adipocytes ts Adipocytes - Small Protein Western blotting 2011 Differential centrifugation Microvesicles 214 21364924 Homo sapiens Thermal- and oxidative stress causes enhanced release of NKG2D ligand-bearing immunosuppressive exosomes in leukemia/lymphoma T and B cells T cells cl Jurkat Protein Western blotting|Immunoelectron microscopy|FACS 2011 Differential centrifugation|Ultracentrifugation|Filtration|Sucrose density gradient|FACS Exosomes 215 21364924 Homo sapiens Thermal- and oxidative stress causes enhanced release of NKG2D ligand-bearing immunosuppressive exosomes in leukemia/lymphoma T and B cells B cells cl Raji Protein Western blotting|Immunoelectron microscopy|FACS 2011 Differential centrifugation|Ultracentrifugation|Filtration|Sucrose density gradient|FACS Exosomes 216 21293856 Homo sapiens Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC Breast cancer cells cl BT474 Protein Western blotting|Immunoelectron microscopy|FACS|Dot blot 2011 Differential centrifugation|Filtration|Ultrafiltration|Ultracentrifugation|Sucrose density gradient Exosomes 217 21293856 Homo sapiens Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC Serum ts Serum - Breast cancer Protein ELISA|Dot blot 2011 Differential centrifugation|Filtration|Ultrafiltration|Ultracentrifugation|Sucrose density gradient Exosomes 218 10694520 Homo sapiens Elevated levels of shed membrane microparticles with procoagulant potential in the peripheral circulating blood of patients with acute coronary syndromes Plasma ts Plasma - Stable angina Protein Immunoaffinity 2000 Immunoaffinity [Annexin-V] Microparticles 219 10694520 Homo sapiens Elevated levels of shed membrane microparticles with procoagulant potential in the peripheral circulating blood of patients with acute coronary syndromes Plasma ts Plasma - Acute coronary syndromes Protein Immunoaffinity 2000 Immunoaffinity [Annexin-V] Microparticles 220 10694520 Homo sapiens Elevated levels of shed membrane microparticles with procoagulant potential in the peripheral circulating blood of patients with acute coronary syndromes Plasma ts Plasma - Noncoronary heart disease Protein Immunoaffinity 2000 Immunoaffinity [Annexin-V] Microparticles 221 9918520 Homo sapiens Shed membrane microparticles with procoagulant potential in human atherosclerotic plaques: a role for apoptosis in plaque thrombogenicity Atherosclerotic plaques ts Atherosclerotic plaques Protein|Lipids Immunohistochemistry|Immunoaffinity 1999 Differential centrifugation|Immunoaffinity [Annexin-V] Apoptotic bodies 222 12514112 Homo sapiens Intravascular tissue factor initiates coagulation via circulating microvesicles and platelets Plasma ts Plasma - Normal Protein Immunoelectron microscopy|FACS|Western blotting 2003 Differential centrifugation|FACS Microvesicles 223 10393703 Homo sapiens In vitro generation of endothelial microparticles and possible prothrombotic activity in patients with lupus anticoagulant Endothelial cells cl HUVECS Protein FACS|Confocal microscopy|Western blotting 1999 Differential centrifugation|Ultracentrifugation Microparticles 224 10393703 Homo sapiens In vitro generation of endothelial microparticles and possible prothrombotic activity in patients with lupus anticoagulant Plasma ts Plasma - Normal Protein Confocal microscopy|FACS 1999 Differential centrifugation Microparticles 225 10393703 Homo sapiens In vitro generation of endothelial microparticles and possible prothrombotic activity in patients with lupus anticoagulant Plasma ts Plasma - Lupus anticoagulant Protein FACS 1999 Differential centrifugation Microparticles 226 12514112 Homo sapiens Intravascular tissue factor initiates coagulation via circulating microvesicles and platelets Platelets ts Platelets Protein Western blotting 2003 Differential centrifugation Microvesicles 227 2942561 Homo sapiens Platelet surface glycoproteins. Studies on resting and activated platelets and platelet membrane microparticles in normal subjects, and observations in patients during adult respiratory distress syndrome and cardiac surgery Plasma ts Plasma - Normal Protein Antibody based methods 1986 Differential centrifugation Microparticles 228 2942561 Homo sapiens Platelet surface glycoproteins. Studies on resting and activated platelets and platelet membrane microparticles in normal subjects, and observations in patients during adult respiratory distress syndrome and cardiac surgery Serum ts Serum - Normal Protein Antibody based methods 1986 Differential centrifugation Microparticles 229 2942561 Homo sapiens Platelet surface glycoproteins. Studies on resting and activated platelets and platelet membrane microparticles in normal subjects, and observations in patients during adult respiratory distress syndrome and cardiac surgery Plasma ts Plasma - Adult respiratory distress syndrome Protein Antibody based methods 1986 Differential centrifugation Microparticles 230 2294986 Homo sapiens Direct detection of activated platelets and platelet-derived microparticles in humans Plasma ts Plasma - Cardiopulmonary bypass Protein FACS 1990 FACS Microparticles 231 2294986 Homo sapiens Direct detection of activated platelets and platelet-derived microparticles in humans Plasma ts Plasma - Standardized bleeding time Protein FACS 1990 FACS Microparticles 232 7697722 Homo sapiens Secretory phospholipase A2 generates the novel lipid mediator lysophosphatidic acid in membrane microvesicles shed from activated cells Red blood cells ts Erythrocyte Lipids Thin layer chromatography|Cytofluorographic analysis 1995 Differential centrifugation Microvesicles 233 7697722 Homo sapiens Secretory phospholipase A2 generates the novel lipid mediator lysophosphatidic acid in membrane microvesicles shed from activated cells Inflammatory fluids ts Inflammatory fluids - Arthritis Lipids Thin layer chromatography|Cytofluorographic analysis 1995 Differential centrifugation Microvesicles 234 10648405 Homo sapiens Cellular origin and procoagulant properties of microparticles in meningococcal sepsis Plasma ts Plasma - Meningococcal sepsis - Survived Protein FACS 2000 Differential centrifugation|FACS Microparticles 235 10648405 Homo sapiens Cellular origin and procoagulant properties of microparticles in meningococcal sepsis Plasma ts Plasma - Normal Protein FACS 2000 Differential centrifugation|FACS Microparticles 236 10648405 Homo sapiens Cellular origin and procoagulant properties of microparticles in meningococcal sepsis Plasma ts Plasma - Meningococcal sepsis - Nonsurvived Protein FACS 2000 Differential centrifugation|FACS Microparticles 237 21293856 Homo sapiens Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC Melanoma cells cl Mel624.38 Protein Dot blot 2011 Differential centrifugation|Filtration|Ultrafiltration|Ultracentrifugation|Sucrose density gradient Exosomes 238 21293856 Homo sapiens Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC Ascites ts Malignant ascites - Ovarian cancer Protein Dot blot 2011 Differential centrifugation|Filtration|Ultrafiltration|Ultracentrifugation|Sucrose density gradient Exosomes 240 10233897 Homo sapiens Elevated levels of circulating procoagulant microparticles in patients with paroxysmal nocturnal hemoglobinuria and aplastic anemia Platelets ts Platelets - Paroxysmal nocturnal hemoglobinuria patients Protein|Lipids FACS 1999 Differential centrifugation|FACS Microparticles 241 16192427 Homo sapiens Circulating endothelial microparticles are associated with vascular dysfunction in patients with end-stage renal failure Plasma ts Plasma - End-stage renal failure patients Protein FACS 2005 Differential centrifugation|FACS Microparticles 242 9151784 Homo sapiens Transcellular activation of platelets and endothelial cells by bioactive lipids in platelet microparticles Platelets ts Platelets Lipids Mass spectrometry|High performance liquid chromatography 1997 Differential centrifugation Microparticles 243 22149170 Homo sapiens The Protein Interaction Network of Extracellular Vesicles Derived from Human Colorectal Cancer Cells Colorectal cancer cells cl HT29 Protein Mass spectrometry [LTQ]|Microarray|Western blotting|Confocal microscopy 2011 Differential centrifugation|Ultrafiltration|Ultracentrifugation|Sucrose density gradient 244 22148876 Homo sapiens Proteomic analysis of microvesicles derived from human mesenchymal stem cells Mesenchymal stem cells ts Mesenchymal stem cells - Rep 1 Protein Western blotting|Mass spectrometry[QTOF] 2011 Differential centrifugation|Ultrafiltration|Ultracentrifugation|Sucrose density gradient|Optiprep density gradient Microvesicles 245 9126269 Homo sapiens Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations T cells cl H9 - non infected Protein|mRNA Radioimmunoassay 1997 Differential centrifugation|Sucrose density gradient Microvesicles 246 18425114 Homo sapiens Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells Glioblastoma cells cl U373vIII Protein Western blotting 2008 Differential centrifugation|Ultracentrifugation Microvesicles 247 15741221 Homo sapiens Tissue-factor-bearing microvesicles arise from lipid rafts and fuse with activated platelets to initiate coagulation Plasma ts Plasma - Normal Protein Western blotting 2005 Differential centrifugation|Immunobeads (TF) Microvesicles 248 15741221 Homo sapiens Tissue-factor-bearing microvesicles arise from lipid rafts and fuse with activated platelets to initiate coagulation Monocytic leukemia cells cl THP-1 Protein Western blotting 2005 Differential centrifugation Microvesicles 249 15741221 Homo sapiens Tissue-factor-bearing microvesicles arise from lipid rafts and fuse with activated platelets to initiate coagulation Monocytes ts Monocytes Protein Western blotting 2005 Differential centrifugation Microvesicles 250 9396452 Homo sapiens Cell-derived microparticles generated in patients during cardiopulmonary bypass are highly procoagulant Plasma ts Plasma - Systemic blood - Cardiopulmonary bypass patients Protein|Lipids FACS|Annexin V-FITC 1997 Differential centrifugation Microparticles 251 9396452 Homo sapiens Cell-derived microparticles generated in patients during cardiopulmonary bypass are highly procoagulant Plasma ts Plasma - Pericardial blood - Cardiopulmonary bypass patients Protein|Lipids FACS|Annexin V-FITC 1997 Differential centrifugation Microparticles 252 9126269 Homo sapiens Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations T cells cl H9 - HIV infected Protein Radioimmunoassay|Northern blotting 1997 Differential centrifugation|Sucrose density gradient Microvesicles 253 9126269 Homo sapiens Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations T4-lymphoblastoid cells cl CEM-SS - HIV non infected Protein Radioimmunoassay 1997 Differential centrifugation|Sucrose density gradient Microvesicles 254 9126269 Homo sapiens Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations T4-lymphoblastoid cells cl CEM-SS - HIV infected Protein Radioimmunoassay 1997 Differential centrifugation|Sucrose density gradient Microvesicles 255 9126269 Homo sapiens Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations Burkitt's lymphoma cl DAUDI - HIV non infected Protein Radioimmunoassay 1997 Differential centrifugation|Sucrose density gradient Microvesicles 256 9126269 Homo sapiens Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations Burkitt's lymphoma cl DAUDI - HIV infected Protein Radioimmunoassay 1997 Differential centrifugation|Sucrose density gradient Microvesicles 257 9126269 Homo sapiens Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations T lymphoblastic leukemia cl MOLT-3 - HIV non infected Protein Radioimmunoassay 1997 Differential centrifugation|Sucrose density gradient Microvesicles 258 9126269 Homo sapiens Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations T lymphoblastic leukemia cl MOLT-3 - HIV infected Protein Radioimmunoassay 1997 Differential centrifugation|Sucrose density gradient Microvesicles 259 18425114 Homo sapiens Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells Glioma cells cl U373 Protein Western blotting 2008 Differential centrifugation|Ultracentrifugation Microvesicles 260 10888925 Homo sapiens Transfer of the chemokine receptor CCR5 between cells by membrane-derived microparticles: a mechanism for cellular human immunodeficiency virus 1 infection Mononuclear cells ts Mononuclear cells Protein Western blotting 2000 Differential centrifugation|Filtration Microparticles 261 12805058 Homo sapiens Sickle blood contains tissue factor-positive microparticles derived from endothelial cells and monocytes Plasma ts Plasma - Sickle cell patients - Crisis Protein|Lipids FACS|Annexin V-FITC 2003 Differential centrifugation|Ultracentrifugation|FACS Microparticles 262 12805058 Homo sapiens Sickle blood contains tissue factor-positive microparticles derived from endothelial cells and monocytes Plasma ts Plasma - Sickle cell patients - Steady state Protein|Lipids FACS|Annexin V-FITC 2003 Differential centrifugation|Ultracentrifugation|FACS Microparticles 263 12805058 Homo sapiens Sickle blood contains tissue factor-positive microparticles derived from endothelial cells and monocytes Plasma ts Plasma - Normal Protein FACS 2003 Differential centrifugation|Ultracentrifugation|FACS Microparticles 264 18425114 Homo sapiens Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells Epidermoid carcinoma cells cl A431 Protein Western blotting 2008 Differential centrifugation|Ultracentrifugation Microvesicles 265 18425114 Homo sapiens Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells Endothelial cells cl HUVECs Protein Western blotting 2008 Differential centrifugation|Ultracentrifugation Microvesicles 266 18425114 Mus musculus Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells Plasma ts Plasma - Tumour Protein Western blotting 2008 Differential centrifugation|Ultracentrifugation Microvesicles 267 12757771 Homo sapiens Endothelial cells release phenotypically and quantitatively distinct microparticles in activation and apoptosis Endothelial cells cl Brain microvascular endothelial cells - ACBRI 376 - Control|TNF alpha|GFD Protein FACS 2003 Differential centrifugation|FACS Microparticles 268 12757771 Homo sapiens Endothelial cells release phenotypically and quantitatively distinct microparticles in activation and apoptosis Endothelial cells cl Glomerular microvascular endothelial cells - ACBRI 128 - Control|TNF alpha|GFD Protein FACS 2003 Differential centrifugation|FACS Microparticles 269 12757771 Homo sapiens Endothelial cells release phenotypically and quantitatively distinct microparticles in activation and apoptosis Endothelial cells cl Coronary artery endothelial cells - ACBRI 377 - Control|TNF alpha|GFD Protein FACS 2003 Differential centrifugation|FACS Microparticles 270 10903724 Homo sapiens Follicular dendritic cells carry MHC class II-expressing microvesicles at their surface Dendritic cells ts Follicular dendritic cells Protein Immunoelectron microscopy 2000 - Microvesicles 271 10903724 Homo sapiens Follicular dendritic cells carry MHC class II-expressing microvesicles at their surface B cells cl RN Protein Immunoelectron microscopy 2000 Differential centrifugation Exosomes 272 8896411 Homo sapiens High shear stress can initiate both platelet aggregation and shedding of procoagulant containing microparticles Platelets ts Platelets Protein|Lipids FACS|Annexin V-FITC 1996 Differential centrifugation|FACS Microparticles 273 12021310 Homo sapiens Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles T cells cl Jurkat Protein Western blotting 2002 Differential centrifugation|Ultracentrifugation Microvesicles 274 12021310 Homo sapiens Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles Melanoma cells cl Me15392 Protein Imunoelectron microscopy|Western blotting|FACS 2002 Differential centrifugation|Ultracentrifugation Microvesicles 275 12021310 Homo sapiens Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles Melanoma cells cl 501mel Protein Imunoelectron microscopy|Western blotting|FACS 2002 Differential centrifugation|Ultracentrifugation Microvesicles 276 12021310 Homo sapiens Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles Melanoma cells cl Me30966 Protein Imunoelectron microscopy|Western blotting|FACS 2002 Differential centrifugation|Ultracentrifugation Microvesicles 277 22030351 Homo sapiens Expression of PTRF in PC-3 cells modulates cholesterol dynamics and the actin cytoskeleton impacting secretion pathways Prostate cancer cells cl PC-3 Protein Mass spectrometry [QTOF] 2011 Differential centrifugation Exosomes 278 10233897 Homo sapiens Elevated levels of circulating procoagulant microparticles in patients with paroxysmal nocturnal hemoglobinuria and aplastic anemia Platelets ts Platelets - Normal Protein|Lipids FACS 1999 Differential centrifugation|FACS Microparticles 279 16192427 Homo sapiens Circulating endothelial microparticles are associated with vascular dysfunction in patients with end-stage renal failure Plasma ts Plasma - Normal Protein FACS 2005 Differential centrifugation|FACS Microparticles 280 15499615 Homo sapiens Microvesicles derived from activated platelets induce metastasis and angiogenesis in lung cancer Lung cancer cells cl A549 Protein|mRNA RT-PCR|FACS 2005 Differential centrifugation|FACS Microvesicles 281 15499615 Homo sapiens Microvesicles derived from activated platelets induce metastasis and angiogenesis in lung cancer Lung cancer cells cl A549 mRNA RT-PCR 2005 Differential centrifugation|Ultracentrifugation Exosomes 282 19234131 Homo sapiens Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR Lung cancer cells cl A549 Protein Western blotting 2009 Differential centrifugation Microvesicles 283 19234131 Homo sapiens Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR Colorectal cancer cells cl DLD-1 Protein Western blotting 2009 Differential centrifugation Microvesicles 284 12796750 Homo sapiens High levels of circulating endothelial microparticles in patients with acute coronary syndromes Plasma ts Plasma - Stable angina Protein FACS 2003 Differential centrifugation|FACS Microparticles 285 12796750 Homo sapiens High levels of circulating endothelial microparticles in patients with acute coronary syndromes Plasma ts Plasma - Unstable angina Protein FACS 2003 Differential centrifugation|FACS Microparticles 286 12417540 Homo sapiens Elevated numbers of tissue-factor exposing microparticles correlate with components of the metabolic syndrome in uncomplicated type 2 diabetes mellitus Plasma ts Plasma - Type 2 diabetes Protein FACS 2002 Differential centrifugation|FACS Microparticles 287 12417540 Homo sapiens Elevated numbers of tissue-factor exposing microparticles correlate with components of the metabolic syndrome in uncomplicated type 2 diabetes mellitus Plasma ts Plasma - Normal Protein FACS 2002 Differential centrifugation|FACS Microparticles 288 12196479 Homo sapiens Type 1 and type 2 diabetic patients display different patterns of cellular microparticles Plasma ts Plasma - Healthy donors Protein|Lipids FACS|Annexin V-FITC 2002 Differential centrifugation|FACS Microparticles 289 12196479 Homo sapiens Type 1 and type 2 diabetic patients display different patterns of cellular microparticles Plasma ts Plasma - Type 1 diabetes Protein|Lipids FACS|Annexin V-FITC 2002 Differential centrifugation|FACS Microparticles 290 12196479 Homo sapiens Type 1 and type 2 diabetic patients display different patterns of cellular microparticles Plasma ts Plasma - Type 2 diabetes Protein|Lipids FACS|Annexin V-FITC 2002 Differential centrifugation|FACS Microparticles 291 15072974 Rattus norvegicus Endothelium-derived microparticles impair endothelial function in vitro Endothelial cells cl RMVECs Protein Western blotting 2004 Differential centrifugation|Ultracentrifugation|FACS Microparticles 292 10415024 Homo sapiens Activated human T cells release bioactive Fas ligand and APO2 ligand in microvesicles T cells cl Jurkat - PHA stimulated Protein Western blotting|FACS 1999 Differential centrifugation|Ultracentrifugation|FACS Microvesicles 293 10415024 Homo sapiens Activated human T cells release bioactive Fas ligand and APO2 ligand in microvesicles T cells ts T cell blasts Protein Western blotting|FACS 1999 Differential centrifugation|Ultracentrifugation|FACS Microvesicles 294 2071604 Homo sapiens Evidence that agonist-induced activation of calpain causes the shedding of procoagulant-containing microvesicles from the membrane of aggregating platelets Platelets ts Platelets Protein Western blotting 1991 Differential centrifugation|Filtration Microvesicles 295 10233897 Homo sapiens Elevated levels of circulating procoagulant microparticles in patients with paroxysmal nocturnal hemoglobinuria and aplastic anemia Platelets ts Platelets - Aplastic anemia patients Lipids FACS 1999 Differential centrifugation|FACS Microparticles 296 12796750 Homo sapiens High levels of circulating endothelial microparticles in patients with acute coronary syndromes Plasma ts Plasma - Normal Protein FACS 2003 Differential centrifugation|FACS Microparticles 297 12796750 Homo sapiens High levels of circulating endothelial microparticles in patients with acute coronary syndromes Plasma ts Plasma - Acute coronary syndrome Protein FACS 2003 Differential centrifugation|FACS Microparticles 298 12796750 Homo sapiens High levels of circulating endothelial microparticles in patients with acute coronary syndromes Plasma ts Plasma - Coronary artery disease Protein FACS 2003 Differential centrifugation|FACS Microparticles 299 12796750 Homo sapiens High levels of circulating endothelial microparticles in patients with acute coronary syndromes Plasma ts Plasma - Myocardial infarction Protein FACS 2003 Differential centrifugation|FACS Microparticles 300 19234131 Homo sapiens Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR Epidermoid carcinoma cells cl A431 Protein Western blotting 2009 Differential centrifugation Microvesicles 301 19234131 Homo sapiens Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR Endothelial cells cl HUVECs Protein Western blotting 2009 Differential centrifugation Microvesicles 302 1321158 Rattus norvegicus Membrane anchoring of the autoantigen GAD65 to microvesicles in pancreatic beta-cells by palmitoylation in the NH2-terminal domain. Pancreatic cells cl Pancreatic cells Protein Immunoelectron microscopy 1992 Differential centrifugation Microvesicles 303 19930720 Homo sapiens Colorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells Colorectal cancer cells cl SW480 Protein|mRNA Western blotting|RT-PCR|Microarray [Illumina] 2009 Differential centrifugation|Ultrafiltration|Optiprep density gradient Microvesicles 304 17478559 Mus musculus Identification and characterization of microvesicles secreted by 3T3-L1 adipocytes: redox- and hormone-dependent induction of milk fat globule-epidermal growth 8-associated microvesicles Adipocytes cl 3T3-L1 Protein Immunoelectron microscopy|Western blotting|Mass spectrometry [LCQ-DECA XP] 2007 Differential centrifugation|Ultracentrifugation|Sucrose density gradient Microvesicles 305 17478559 Rattus norvegicus Identification and characterization of microvesicles secreted by 3T3-L1 adipocytes: redox- and hormone-dependent induction of milk fat globule-epidermal growth 8-associated microvesicles Adipocytes ts Adipocytes Protein Western blotting 2007 Differential centrifugation Microvesicles 306 16342139 Homo sapiens Proteomic analysis of malignant lymphocyte membrane microparticles using double ionization coverage optimization T cells cl CEM T cell - PHA activation Protein Mass spectrometry [MALDI TOF/TOF]|Mass spectrometry [QTOF] 2006 Differential centrifugation Microparticles 307 16342139 Homo sapiens Proteomic analysis of malignant lymphocyte membrane microparticles using double ionization coverage optimization T cells cl CEM T cell - ActD activation Protein Mass spectrometry [MALDI TOF/TOF]|Mass spectrometry [QTOF] 2006 Differential centrifugation Microparticles 308 16342139 Homo sapiens Proteomic analysis of malignant lymphocyte membrane microparticles using double ionization coverage optimization B cells ts B cells - Chronic B cell lymphoid patient Protein Mass spectrometry [MALDI TOF/TOF]|Mass spectrometry [QTOF] 2006 Differential centrifugation Microparticles 309 17536014 Homo sapiens Endothelial progenitor cell derived microvesicles activate an angiogenic program in endothelial cells by a horizontal transfer of Mrna Endothelial cells ts Endothelial cells - Healthy donors Protein|mRNA FACS|RT-PCR|Microarray [Illumina] 2007 Differential centrifugation|Ultracentrifugation|FACS Microvesicles 310 22148876 Homo sapiens Proteomic analysis of microvesicles derived from human mesenchymal stem cells Mesenchymal stem cells ts Mesenchymal stem cells - Rep 2 Protein Western blotting|Mass spectrometry[QTOF] 2011 Differential centrifugation|Ultrafiltration|Ultracentrifugation|Sucrose density gradient|Optiprep density gradient Microvesicles 311 22148876 Homo sapiens Proteomic analysis of microvesicles derived from human mesenchymal stem cells Mesenchymal stem cells ts Mesenchymal stem cells - Rep 3 Protein Western blotting|Mass spectrometry[QTOF] 2011 Differential centrifugation|Ultrafiltration|Ultracentrifugation|Sucrose density gradient|Optiprep density gradient Microvesicles 312 15499615 Homo sapiens Microvesicles derived from activated platelets induce metastasis and angiogenesis in lung cancer Lung cancer cells cl CRL 2062 Protein FACS 2005 Differential centrifugation|FACS Microvesicles 313 15499615 Homo sapiens Microvesicles derived from activated platelets induce metastasis and angiogenesis in lung cancer Lung cancer cells cl CRL 2066 Protein FACS 2005 Differential centrifugation|FACS Microvesicles 314 15499615 Homo sapiens Microvesicles derived from activated platelets induce metastasis and angiogenesis in lung cancer Lung cancer cells cl HTB 177 Protein FACS 2005 Differential centrifugation|FACS Microvesicles 315 15499615 Homo sapiens Microvesicles derived from activated platelets induce metastasis and angiogenesis in lung cancer Lung cancer cells cl HTB 183 Protein FACS 2005 Differential centrifugation|FACS Microvesicles 316 18472965 Homo sapiens Cathepsin B mediates the pH-dependent proinvasive activity of tumor-shed microvesicles Ovarian cancer cells cl CABA I Protein Westen blotting|Zymography 2008 Differential centrifugation Microvesicles 317 19266099 Homo sapiens Transfer of microRNAs by embryonic stem cell microvesicles Embryonic stem cells ts Embryonic stem cells mRNA|miRNA|snRNA RT-PCR 2009 Differential centrifugation Microvesicles 318 19483673 Homo sapiens Y-box protein-1 is actively secreted through a non-classical pathway and acts as an extracellular mitogen Monocytes ts Monocytes Protein Western blotting 2009 Differential centrifugation|Filtration Microvesicles 319 20615901 Homo sapiens Export of microRNAs and microRNA-protective protein by mammalian cells Lung cancer cells cl HepG2 miRNA RT-PCR 2010 Differential centrifugation Microvesicles 320 20615901 Homo sapiens Export of microRNAs and microRNA-protective protein by mammalian cells Epithelial cells cl A549 miRNA RT-PCR 2010 Differential centrifugation Microvesicles 321 19951903 Homo sapiens MicroRNA-29a regulates intestinal membrane permeability in patients with irritable bowel syndrome Plasma ts Plasma - Normal miRNA Microarray [ArrayExpress]|RT-PCR 2010 Differential centrifugation|Filtration Microvesicles 322 19951903 Homo sapiens MicroRNA-29a regulates intestinal membrane permeability in patients with irritable bowel syndrome Plasma ts Plasma - Iritable bowel syndrome patients miRNA Microarray [ArrayExpress]|RT-PCR 2010 Differential centrifugation|Filtration Microvesicles 323 20304794 Homo sapiens Functional delivery of viral miRNAs via exosomes B cells ts B cells - Transformed with Epstein–Barr virus Protein Western blotting 2010 Differential centrifugation Exosomes 324 20079801 Mus musculus Microvesicle entry into marrow cells mediates tissue-specific changes in mRNA by direct delivery of mRNA and induction of transcription Lung cells ts Lung cells Protein|miRNA FACS|RT-PCR 2010 Differential centrifugation|FACS Microvesicles 325 19289371 Homo sapiens Exosomal microRNA: a diagnostic marker for lung cancer Plasma ts Plasma - Lung adenocarcinoma patients miRNA Microarray 2009 Size exclusion chromatography|Immunobeads (EpCAM) Exosomes 326 20428099 Homo sapiens Nucleic acids within urinary exosomes/microvesicles are potential biomarkers for renal disease Urine ts Urine - Normal mRNA RT-PCR 2010 Differential centrifugation|Ultracentrifugation Microvesicles 327 20428099 Homo sapiens Nucleic acids within urinary exosomes/microvesicles are potential biomarkers for renal disease Urine ts Urine - Normal mRNA RT-PCR 2010 Differential centrifugation|Ultracentrifugation Exosomes 328 20428099 Rattus norvegicus Nucleic acids within urinary exosomes/microvesicles are potential biomarkers for renal disease Urine ts Urine - Renal acidosis mRNA RT-PCR 2010 Differential centrifugation|Ultracentrifugation Microvesicles 329 20304794 Homo sapiens Functional delivery of viral miRNAs via exosomes B cells cl B95-8 miRNA RT-PCR 2010 Differential centrifugation Exosomes 330 20304794 Homo sapiens Functional delivery of viral miRNAs via exosomes B cells cl X50-7 miRNA RT-PCR 2010 Differential centrifugation Exosomes 331 19627513 Homo sapiens Exosomes from human saliva as a source of microRNA biomarkers Saliva ts Saliva - Normal Protein|miRNA Western blotting|RT-PCR 2010 Differential centrifugation|Ultracentrifugation Exosomes 332 19627513 Homo sapiens Exosomes from human saliva as a source of microRNA biomarkers Saliva ts Saliva - Sjogren’s syndrome patients miRNA Microarray 2010 Differential centrifugation|Ultracentrifugation Exosomes 333 20976003 Homo sapiens Selective release of microRNA species from normal and malignant mammary epithelial cells Breast cancer cells cl MCF-7 Protein|miRNA Slot blot|RT-PCR|Microarray 2010 Differential centrifugation|Filtration Exosomes 334 20976003 Homo sapiens Selective release of microRNA species from normal and malignant mammary epithelial cells Breast cancer cells cl MDA-MB-231 Protein|miRNA Slot blot|RT-PCR 2010 Differential centrifugation|Filtration Exosomes 335 20976003 Homo sapiens Selective release of microRNA species from normal and malignant mammary epithelial cells Breast cancer cells cl BT-20 Protein|miRNA Slot blot|RT-PCR 2010 Differential centrifugation|Filtration Exosomes 336 20976003 Homo sapiens Selective release of microRNA species from normal and malignant mammary epithelial cells Breast cancer cells cl MCF 10A Protein|miRNA Slot blot|RT-PCR 2010 Differential centrifugation|Filtration Exosomes 337 20976003 Homo sapiens Selective release of microRNA species from normal and malignant mammary epithelial cells Breast cancer cells cl SK-BR-3 miRNA RT-PCR 2010 Differential centrifugation|Filtration Exosomes 338 20621060 Rattus norvegicus Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation Adipocytes cl 3T3-L1 mRNA|miRNA RT-PCR 2010 Differential centrifugation|Ultracentrifugation Microvesicles 339 20621060 Rattus norvegicus Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation Serum ts Serum mRNA RT-PCR 2010 Differential centrifugation|Ultracentrifugation Microvesicles 340 20615901 Homo sapiens Export of microRNAs and microRNA-protective protein by mammalian cells Lung cancer cells cl HepG2 miRNA RT-PCR 2010 Differential centrifugation Exosomes 341 20615901 Homo sapiens Export of microRNAs and microRNA-protective protein by mammalian cells Epithelial cells cl A549 miRNA RT-PCR 2010 Differential centrifugation Exosomes 342 22965126 Mus musculus Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells. Neuronal cells cl GT1-7 - Unifected Rep 1 miRNA RT-PCR|Western blotting 2012 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 343 22965126 Mus musculus Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells. Neuronal cells cl GT1-7 - Unifected Rep 2 miRNA RT-PCR 2012 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 344 22965126 Mus musculus Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells. Neuronal cells cl GT1-7 - Prion infected Rep 1 miRNA RT-PCR|Western blotting 2012 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 345 22965126 Mus musculus Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells. Neuronal cells cl GT1-7 - Prion infected Rep 2 miRNA RT-PCR 2012 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 346 22965126 Mus musculus Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells. Neuronal cells cl GT1-7 - Prion infected and uninfected Protein|miRNA RNA deep sequencing 2012 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 347 22285593 Homo sapiens Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes. Colorectal cancer cells cl LIM1863 - Ultracentrifugation Protein Mass spectrometry [Orbitrap]|Western blotting 2012 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 348 22285593 Homo sapiens Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes. Colorectal cancer cells cl LIM1863 - EpCAM immunoaffinity Protein Mass spectrometry [Orbitrap]|Western blotting 2012 Differential centrifugation|Filtration|Immunobeads (EpCAM)|Ultracentrifugation Exosomes 349 22285593 Homo sapiens Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes. Colorectal cancer cells cl LIM1863 - OptiPrep density gradient Protein Mass spectrometry [Orbitrap]|Western blotting 2012 Differential centrifugation|Filtration|Ultracentrifugation|Optiprep density gradient Exosomes 353 24115447 Homo sapiens Comparative proteomics evaluation of plasma exosome isolation techniques and assessment of the stability of exosomes in normal human blood plasma Plasma ts Plasma - Normal Protein Mass spectrometry [Orbitrap Velos]|Western blotting 2013 Differential centrifugation|Filtration|Ultracentrifugation Exosomes 354 24115447 Homo sapiens Comparative proteomics evaluation of plasma exosome isolation techniques and assessment of the stability of exosomes in normal human blood plasma Plasma ts Plasma - Normal Protein Mass spectrometry [Orbitrap Velos]|Western blotting 2013 Differential centrifugation|Filtration|Ultracentrifugation|Optiprep density gradient Exosomes 355 24115447 Homo sapiens Comparative proteomics evaluation of plasma exosome isolation techniques and assessment of the stability of exosomes in normal human blood plasma Plasma ts Plasma - Normal Protein Mass spectrometry [Orbitrap Velos]|Western blotting 2013 Differential centrifugation|Filtration|Ultracentrifugation|Immunobeads (EpCAM) Exosomes 357 24352158 Homo sapiens Characterization and deep sequencing analysis of exosomal miRNA in human urine Urine ts Urine - Normal miRNA RNA deep sequencing 0 Differential centrifugation|Norgen Biotek Exosome kit Exosomes 365 11878797 Homo sapiens Phospholipid composition of cell-derived microparticles determined by one-dimensional high-performance thin-layer chromatography. Plasma ts Normal-Plasma Lipids Thin layer chromatography 2002 - Microparticles 366 12414662 Homo sapiens Extracellular membrane vesicles from tumor cells promote angiogenesis via sphingomyelin. Endothelial cells cl HMEC-1 Lipids Thin layer chromatography 2002 - Membrane vesicles 367 12746840 Homo sapiens Proteomic analysis of human prostasomes. Seminal fluid ts Normal donors-Seminal fluid Protein Mass spectrometry 2003 - Prostasomes 368 16103114 Neisseria meningitidis Biochemical and functional characterization of membrane blebs purified from Neisseria meningitidis serogroup B. Neisseria meningitidis - Normal-Neisseria meningitidis Serogroup B Protein Mass spectrometry 2005 - Membrane vesicles 369 16212402 Homo sapiens The platelet microparticle proteome. Platelets ts Normal donors-Platelets Protein Mass spectrometry 2005 - Microparticles 370 16456881 Neisseria meningitidis Outer membrane vesicles from group B Neisseria meningitidis delta gna33 mutant: proteomic and immunological comparison with detergent-derived outer membrane vesicles. Neisseria meningitidis - Δgna33-Neisseria meningitidis MC58 Protein Mass spectrometry 2006 - Membrane vesicles 371 16456881 Neisseria meningitidis Outer membrane vesicles from group B Neisseria meningitidis delta gna33 mutant: proteomic and immunological comparison with detergent-derived outer membrane vesicles. Neisseria meningitidis - Δgna33-Neisseria meningitidis NZ98/254 Protein Mass spectrometry 2006 - Membrane vesicles 372 17096383 Mus musculus Analysis of the extracellular matrix vesicle proteome in mineralizing osteoblasts. Osteoblasts cl MC3T3-E1 Protein Mass spectrometry 2007 - Matrix vesicles 373 17787032 Escherichia coli Global proteomic profiling of native outer membrane vesicles derived from Escherichia coli. Escherichia coli - Normal-Escherichia coli DH5α Protein Mass spectrometry 2007 - Membrane vesicles 374 18039940 Cryptococcus neoformans Extracellular vesicles produced by Cryptococcus neoformans contain protein components associated with virulence. Cryptococcus neoformans - Normal-Cryptococcus neoformans Protein Mass spectrometry 2008 - Exosomes/Extracellular vesicles 375 18095356 Gallus gallus Proteome analysis of matrix vesicles isolated from femurs of chicken embryo. 17-day-old embryo leg bone - Normal-17-day-old embryo leg bone Protein Mass spectrometry 2008 - Matrix vesicles 376 18346024 Homo sapiens The proteome of red cell membranes and vesicles during storage in blood bank conditions. Red blood cells cl Microvesicle, Storage day 21-Red blood cells Protein Mass spectrometry 2008 - Microvesicles/Nanovesicles 377 18346024 Homo sapiens The proteome of red cell membranes and vesicles during storage in blood bank conditions. Red blood cells cl Microvesicle, Storage day 3-Red blood cells Protein Mass spectrometry 2008 - Microvesicles/Nanovesicles 378 18346024 Homo sapiens The proteome of red cell membranes and vesicles during storage in blood bank conditions. Red blood cells cl Microvesicle, Storage day 42-Red blood cells Protein Mass spectrometry 2008 - Microvesicles/Nanovesicles 379 18346024 Homo sapiens The proteome of red cell membranes and vesicles during storage in blood bank conditions. Red blood cells cl Nanovesicle, Storage day 21-Red blood cells Protein Mass spectrometry 2008 - Microvesicles/Nanovesicles 380 18346024 Homo sapiens The proteome of red cell membranes and vesicles during storage in blood bank conditions. Red blood cells cl Nanovesicle, Storage day 3-Red blood cells Protein Mass spectrometry 2008 - Microvesicles/Nanovesicles 381 18346024 Homo sapiens The proteome of red cell membranes and vesicles during storage in blood bank conditions. Red blood cells cl Nanovesicle, Storage day 42-Red blood cells Protein Mass spectrometry 2008 - Microvesicles/Nanovesicles 382 18373357 Homo sapiens Isolation and identification of potential urinary microparticle biomarkers of bladder cancer. Urine ts Normal donors-Urine Protein Mass spectrometry 2008 - Microparticles 383 18373357 Homo sapiens Isolation and identification of potential urinary microparticle biomarkers of bladder cancer. Urine ts Patients of bladder cancer-Urine Protein Mass spectrometry 2008 - Microparticles 384 18482993 Homo sapiens Protein composition of human epididymosomes collected during surgical vasectomy reversal: a proteomic and genomic approach. Epididymal fluid ts Normal-Epididymal fluid Protein Mass spectrometry 2008 - Prostasomes 385 18563738 Homo sapiens Comparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles. Endothelial cells cl Endothelial cells (HUVEC) Protein Mass spectrometry 2008 - Microparticles 386 18563738 Homo sapiens Comparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles. Endothelial cells cl Treated by PAI-1-Endothelial cell (HUVEC) Protein Mass spectrometry 2008 - Microparticles 387 18563738 Homo sapiens Comparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles. Endothelial cells cl Treated by TNF-alpha-Endothelial cells (HUVEC) Protein Mass spectrometry 2008 - Microparticles 388 18570454 Homo sapiens Proteomic analysis of exosomes from human neural stem cells by flow field-flow fractionation and nanoflow liquid chromatography-tandem mass spectrometry. Neural stem cells cl Neural stem cells (HB1.F3) Protein Mass spectrometry 2008 - Exosomes/Membrane vesicles 389 18819103 Homo sapiens Structural heterogeneity and protein composition of exosome-like vesicles (prostasomes) in human semen. Seminal fluid ts Normal donors-Seminal fluid Protein Mass spectrometry 2009 - Exosomes/Prostasomes 390 19158352 Homo sapiens Characterization of PKD protein-positive exosome-like vesicles. Urine ts Patients of autosomal recessive polycystic kidney disease-Urine Protein Mass spectrometry 2009 - Exosomes/Membrane particles 391 19327352 Bos taurus Anchorage-independent growth of breast carcinoma cells is mediated by serum exosomes. Serum ts Normal-Fetal bovine serum Protein Mass spectrometry 2009 - Exosomes 392 19351151 Mus musculus Characterization of vesicles secreted from insulinoma NIT-1 cells. Pancreatic cells - Pancreatic beta cell (NIT-1) Protein Mass spectrometry 2009 - Exosomes 393 19369228 Homo sapiens Proteomic analysis reveals presence of platelet microparticles in endothelial progenitor cell cultures. Endothelial cells - Normal-Endothelial progenitor cells Protein Mass spectrometry 2009 - Microparticles 394 19389847 Homo sapiens Mesenchymal stem cell-derived microvesicles protect against acute tubular injury. Mesenchymal stem cells - Normal-Mesenchymal stem cells mRNA Microarray 2009 - Microvesicles 395 19413345 Homo sapiens Proteomic analysis of malignant B-cell derived microparticles reveals CD148 as a potentially useful antigenic biomarker for mantle cell lymphoma diagnosis. B cells - Patients of chronic lymphocytic leukemia-B cells Protein Mass spectrometry 2009 - Microparticles 396 19413345 Homo sapiens Proteomic analysis of malignant B-cell derived microparticles reveals CD148 as a potentially useful antigenic biomarker for mantle cell lymphoma diagnosis. B cells - Patients of mantle cell lymphoma-B cells Protein Mass spectrometry 2009 - Microparticles 397 19413345 Homo sapiens Proteomic analysis of malignant B-cell derived microparticles reveals CD148 as a potentially useful antigenic biomarker for mantle cell lymphoma diagnosis. B cells - Patients of small cell lymphoma-B cells Protein Mass spectrometry 2009 - Microparticles 398 19530224 Homo sapiens Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes. Keratinocytes - Differentiated-Keratinocytes Protein Mass spectrometry 2009 - Exosomes 399 19530224 Homo sapiens Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes. Keratinocytes - Undifferentiated-Keratinocytes Protein Mass spectrometry 2009 - Exosomes 400 19548894 Acinetobacter baumannii Proteome analysis of outer membrane vesicles from a clinical Acinetobacter baumannii isolate. Acinetobacter baumannii - Normal-Acinetobacter baumannii DU202 Protein Mass spectrometry 2009 - Membrane vesicles 401 19548909 Homo sapiens Differential stimulation of monocytic cells results in distinct populations of microparticles. Monocytes - Monocytes (THP-1) Protein Mass spectrometry 2009 - Microparticles 402 19548909 Homo sapiens Differential stimulation of monocytic cells results in distinct populations of microparticles. Monocytes - Stimulated by IgG-Monocytes (THP-1) Protein Mass spectrometry 2009 - Microparticles 403 19548909 Homo sapiens Differential stimulation of monocytic cells results in distinct populations of microparticles. Monocytes - Stimulated by LPS-Monocytes (THP-1) Protein Mass spectrometry 2009 - Microparticles 404 19548909 Homo sapiens Differential stimulation of monocytic cells results in distinct populations of microparticles. Monocytes - Stimulated by P-selectin-Ig-Monocytes (THP-1) Protein Mass spectrometry 2009 - Microparticles 405 19650833 Homo sapiens Human liver stem cell-derived microvesicles accelerate hepatic regeneration in hepatectomized rats. Hepatocytes - Normal-Hepatocytes mRNA Microarray 2010 - Microvesicles 406 19806257 Homo sapiens Proteomic and functional characterisation of platelet microparticle size classes. Platelets - Normal donors-Platelets Protein Mass spectrometry 2009 - Microparticles 407 19834908 Staphylococcus aureus Gram-positive bacteria produce membrane vesicles: proteomics-based characterization of Staphylococcus aureus-derived membrane vesicles. Staphylococcus aureus - Normal-Staphylococcus aureus ATCC14458 Protein Mass spectrometry 2009 - Membrane vesicles 408 20031610 Homo sapiens Proteomics, metabolomics, and immunomics on microparticles derived from human atherosclerotic plaques. Carotid atherosclerotic plaques - Normal-Carotid atherosclerotic plaque metabolite Proton Nucelar Magnetic Resonance Spectrometry 2009 - Microparticles 409 20031610 Homo sapiens Proteomics, metabolomics, and immunomics on microparticles derived from human atherosclerotic plaques. Carotid atherosclerotic plaques - Patients of carotid atherosclerosis-Carotid atherosclerotic plaque Protein Mass spectrometry 2009 - Microparticles 410 20052414 Homo sapiens Nanostructural and transcriptomic analyses of human saliva derived exosomes. Saliva - Normal-Saliva mRNA Microarray 2010 - Exosomes/Membrane vesicles 411 20124223 Homo sapiens Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes. Squamous carcinoma cells - Squamous carcinoma cell (A431) Protein Mass spectrometry 2010 - Exosomes 412 20156641 Homo sapiens Proteomics of microparticles after deep venous thrombosis. Plasma - Normal donors and patients of deep venous thrombosis-Plasma Protein Mass spectrometry 2010 - Membrane vesicles/Microparticles 413 20535238 Rattus norvegicus Candidate biomarkers in exosome-like vesicles purified from rat and mouse urine samples. Urine ts Rats of liver injury-Urine Protein Mass spectrometry 2010 - Exosomes 414 20559436 Saccharomyces cerevisiae Characterization of yeast extracellular vesicles: evidence for the participation of different pathways of cellular traffic in vesicle biogenesis. Saccharomyces cerevisiae - Normal-Saccharomyces cerevisiae Protein Mass spectrometry 2010 - Extracellular vesicles 415 20687614 Myxococcus xanthus Profiling the outer membrane proteome during growth and development of the social bacterium Myxococcus xanthus by selective biotinylation and analyses of outer membrane vesicles. Myxococcus xanthus - Developmental cell-Myxococcus xanthus DK1622 Protein Mass spectrometry 2010 - Membrane vesicles 416 20687614 Myxococcus xanthus Profiling the outer membrane proteome during growth and development of the social bacterium Myxococcus xanthus by selective biotinylation and analyses of outer membrane vesicles. Myxococcus xanthus - Vegetative cell-Myxococcus xanthus DK1622 Protein Mass spectrometry 2010 - Membrane vesicles 417 20956325 Bacillus anthracis Bacillus anthracis produces membrane-derived vesicles containing biologically active toxins. Bacillus anthracis - Normal-Bacillus anthracis Sterne strain 34F2 Lipids Gas chromatography 2010 - Extracellular vesicles 418 21049385 Homo sapiens The plasma microparticle proteome. Plasma - Normal donors-Plasma Protein Mass spectrometry 2010 - Microparticles 419 21136642 Mus musculus Oligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons? Oligodendrocytes - Normal-Oligodendrocytes Protein Mass spectrometry 2007 - Exosomes 420 21136987 Helicobacter pylori Proteomic and functional characterization of the outer membrane vesicles from the gastric pathogen Helicobacter pylori. Helicobacter pylori - Normal-Helicobacter pylori J99 Protein Mass spectrometry 2009 - Membrane vesicles 421 21136987 Helicobacter pylori Proteomic and functional characterization of the outer membrane vesicles from the gastric pathogen Helicobacter pylori. Helicobacter pylori - Normal-Helicobacter pylori NCTC 11637 Protein Mass spectrometry 2009 - Membrane vesicles 422 21138299 Francisella philomiragia Proteomic characterization and functional analysis of outer membrane vesicles of Francisella novicida suggests possible role in virulence and use as a vaccine. Francisella philomiragia - Normal-Francisella philomiragia ATCC25015 Protein Mass spectrometry 2011 - Membrane vesicles 423 21138299 Francisella tularensis Proteomic characterization and functional analysis of outer membrane vesicles of Francisella novicida suggests possible role in virulence and use as a vaccine. Francisella tularensis - Normal-Francisella tularensis subsp. Novicida ATCC15482 Protein Mass spectrometry 2011 - Membrane vesicles 424 21179422 Mus musculus Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA. Mast cells - Mast cells (MC/9) mRNA Microarray 2010 - Exosomes/Nanovesicles 425 21179422 Mus musculus Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA. Mast cells - Oxidatively stressed-Mast cells (MC/9) mRNA Microarray 2010 - Exosomes/Nanovesicles 426 21386968 Acinetobacter baumannii Acinetobacter baumannii secretes cytotoxic outer membrane protein A via outer membrane vesicles. Acinetobacter baumannii - Normal-Acinetobacter baumannii ATCC 19606T Protein Mass spectrometry 2011 - Membrane vesicles 427 21408115 Edwardsiella tarda Outer membrane vesicles as a candidate vaccine against edwardsiellosis. Edwardsiella tarda - Normal-Edwardsiella tarda ED45 Protein Mass spectrometry 2011 - Membrane vesicles 428 21515422 Homo sapiens Proteomic characterization of biogenesis and functions of matrix vesicles released from mineralizing human osteoblast-like cells. Osteosarcoma cells - Normal-Osteosarcoma cell (Saos-2 ATCC HTB-85) Protein Mass spectrometry 2011 - Matrix vesicles 429 21595033 Homo sapiens Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy. Urine ts Normal donors-Urine Protein Mass spectrometry 2011 - Exosomes 430 21595033 Homo sapiens Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy. Urine ts Patients of basement membrane nephropathy-Urine Protein Mass spectrometry 2011 - Exosomes 431 21595033 Homo sapiens Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy. Urine ts Patients of early IgA nephropathy-Urine Protein Mass spectrometry 2011 - Exosomes 432 21751344 Pseudomonas aeruginosa Proteomic analysis of outer membrane vesicles derived from Pseudomonas aeruginosa. Pseudomonas aeruginosa - Normal-Pseudomonas aeruginosa PAO1 Protein Mass spectrometry 2011 - Exosomes/Membrane vesicles 433 22014850 Rattus norvegicus Proteomics of microparticles after experimental pulmonary embolism. Plasma - Normal rat-Plasma Protein Mass spectrometry 2012 - Microparticles 434 22014850 Rattus norvegicus Proteomics of microparticles after experimental pulmonary embolism. Plasma - Rat of pulmonary embolism model-Plasma Protein Mass spectrometry 2012 - Microparticles 435 22031862 Mus musculus Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes. Dendritic cells - Bone marrow-derived immature dendritic cells miRNA Microarray 2012 - Exosomes/Nanovesicles 436 22031862 Mus musculus Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes. Dendritic cells - Bone marrow-derived mature dendritic cells miRNA Microarray 2012 - Exosomes/Nanovesicles 437 22106071 Homo sapiens Proteomic analysis of urine exosomes by multidimensional protein identification technology (MudPIT). Urine ts Normal donors-Urine Protein Mass spectrometry 2012 - Exosomes/Membrane vesicles 438 22114730 Staphylococcus aureus Staphylococcus aureus produces membrane-derived vesicles that induce host cell death. Staphylococcus aureus - Normal-Staphylococcus aureus 06ST1048 Protein Mass spectrometry 2011 - Membrane vesicles/Nanovesicles 439 22129587 Bos taurus Bovine milk exosome proteome. Milk - Normal cow-Milk Protein Mass spectrometry 2012 - Exosomes/Membrane vesicles 440 22251860 Homo sapiens RNA expression patterns in serum microvesicles from patients with glioblastoma multiforme and controls. Serum - Normal-Serum mRNA Microarray 2012 - Exosomes/Microvesicles 441 22251860 Homo sapiens RNA expression patterns in serum microvesicles from patients with glioblastoma multiforme and controls. Serum - Patients of glioblastoma -Serum mRNA Microarray 2012 - Exosomes/Microvesicles 442 22288420 Paracoccidioides brasiliensis Vesicle and vesicle-free extracellular proteome of Paracoccidioides brasiliensis: comparative analysis with other pathogenic fungi. Paracoccidioides brasiliensis - Normal-Paracoccidioides brasiliensis Pb18 Protein Mass spectrometry 2012 - Extracellular vesicles 443 22329422 Homo sapiens Quantitative proteome profiling of normal human circulating microparticles. Plasma - Normal-Platelet-poor plasma Protein Mass spectrometry 2012 - Microparticles 444 22418980 Homo sapiens A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes. Urine ts Normal_high density-Urine Protein Mass spectrometry 2012 - Exosomes 445 22418980 Homo sapiens A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes. Urine ts Normal_low density-Urine Protein Mass spectrometry 2012 - Exosomes 446 22428779 Klebsiella pneumoniae Klebsiella pneumoniae secretes outer membrane vesicles that induce the innate immune response. Klebsiella pneumoniae - Normal-Klebsiella pneumoniae ATCC 13883 Protein Mass spectrometry 2012 - Membrane vesicles 447 22444574 Homo sapiens Proteomic analysis of microvesicles in human saliva by gel electrophoresis with liquid chromatography-mass spectrometry. Saliva - Normal donors-Saliva Protein Mass spectrometry 2012 - Exosomes/Microvesicles 448 22448133 Pseudomonas aeruginosa Vesiculation from Pseudomonas aeruginosa under SOS. Pseudomonas aeruginosa - Normal-Pseudomonas aeruginosa PAO1 Protein Mass spectrometry 2012 - Membrane vesicles 449 22448133 Pseudomonas aeruginosa Vesiculation from Pseudomonas aeruginosa under SOS. Pseudomonas aeruginosa - ΔlexAN-Pseudomonas aeruginosa PAO1 Protein Mass spectrometry 2012 - Membrane vesicles 450 22451062 Homo sapiens A hyphenated microLC-Q-TOF-MS platform for exosomal lipidomics investigations: application to RCC urinary exosomes. Urine ts Normal-Urine Lipids Mass spectrometry 2012 - Exosomes 451 22451062 Homo sapiens A hyphenated microLC-Q-TOF-MS platform for exosomal lipidomics investigations: application to RCC urinary exosomes. Urine ts Patients of renal cell carcinoma-Urine Lipids Mass spectrometry 2012 - Exosomes 452 22506041 Mus musculus Cardiomyocyte microvesicles contain DNA/RNA and convey biological messages to target cells. Cardiomyocyte cells cl Cardiomyocyte cells (HL-1) mRNA Microarray 2012 - Exosomes/Membrane vesicles/Microvesicles/Prostasomes 453 22635005 Homo sapiens Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. Melanoma cells cl B16-F10, SK-MEL-202, SK-MEL035, SK-MEL-265 Protein Mass spectrometry 2012 - Exosomes 454 22669077 Homo sapiens The proteome of erythrocyte-derived microparticles from plasma: new clues for erythrocyte aging and vesiculation. Blood - Normal-Blood Protein Mass spectrometry 2012 - Microparticles 455 22682234 Homo sapiens Microparticle conferred microRNA profiles - implications in the transfer and dominance of cancer traits. T lymphoblastic leukemia cl Drug-resistant acute lymphoblastic leukemia cell (CCRF-CEM MDR variant VLB100) miRNA Microarray 2012 - Membrane vesicles/Microparticles 456 22682234 Homo sapiens Microparticle conferred microRNA profiles - implications in the transfer and dominance of cancer traits. Mammary adenocarcinoma cl Normal-Drug-resistant breast adenocarcinoma cells (MCF-7 MDR variant MCF-7/DX) miRNA Microarray 2012 - Membrane vesicles/Microparticles 457 22723089 Homo sapiens Exosomes as Biomarker Enriched Microvesicles: Characterization of Exosomal Proteins derived from a Panel of Prostate Cell Lines with distinct AR phenotypes. Prostate cancer cells cl PC3, DU145, VcaP, LNCaP, C4-2, RWPE-1 Lipids Mass spectrometry 2012 - Exosomes/Membrane vesicles/Microvesicles 458 22740476 Homo sapiens Restoration of full-length APC protein in SW480 colon cancer cells induces exosome-mediated secretion of DKK-4. Colorectal cancer cells cl SW480 Protein Mass spectrometry 2012 - Exosomes 459 22745761 Paracoccidioides brasiliensis Lipidomic Analysis of Extracellular Vesicles from the Pathogenic Phase of Paracoccidioides brasiliensis. Paracoccidioides brasiliensis - Normal-Paracoccidioides brasiliensis Pb18 Lipids Mass spectrometry 2012 - Extracellular vesicles 460 22745761 Paracoccidioides brasiliensis Lipidomic Analysis of Extracellular Vesicles from the Pathogenic Phase of Paracoccidioides brasiliensis. Paracoccidioides brasiliensis - Normal-Paracoccidioides brasiliensis Pb3 Lipids Mass spectrometry 2012 - Extracellular vesicles 461 22848702 Homo sapiens Medulloblastoma exosome proteomics yield functional roles for extracellular vesicles. Medulloblastoma cells - Medulloblastoma cells (D283MED) Protein Mass spectrometry 2012 - Exosomes/Membrane vesicles/Extracellular vesicles 462 22849433 Homo sapiens Selective extracellular vesicle-mediated export of an overlapping set of microRNAs from multiple cell types. Embryonic kidney cells - miR-146a-treated-Embryonic kidney cells (HEK293T) miRNA Next-generation sequencing 2012 - Extracellular vesicle/Extracellular vesicles 463 22849433 Homo sapiens Selective extracellular vesicle-mediated export of an overlapping set of microRNAs from multiple cell types. Embryonic kidney cells - Embryonic kidney cells (HEK293T) miRNA Next-generation sequencing 2012 - Extracellular vesicle/Extracellular vesicles 464 22909304 Pseudomonas aeruginosa Identification of proteins associated with the Pseudomonas aeruginosa biofilm extracellular matrix. Pseudomonas aeruginosa - Normal_biofilm-Pseudomonas aeruginosa PAO1 Protein Mass spectrometry 2012 - Membrane vesicles 465 22909304 Pseudomonas aeruginosa Identification of proteins associated with the Pseudomonas aeruginosa biofilm extracellular matrix. Pseudomonas aeruginosa - Normal_planktonic culture-Pseudomonas aeruginosa PAO1 Protein Mass spectrometry 2012 - Membrane vesicles 466 22966805 Acinetobacter baumannii Extracellular proteome of a highly invasive multidrug-resistant clinical strain of Acinetobacter baumannii. Acinetobacter baumannii - Normal-Acinetobacter baumannii AbH12O-A2 Protein Mass spectrometry 2012 - Membrane vesicles 467 23000592 Homo sapiens In-depth analysis of the secretome identifies three major independent secretory pathways in differentiating human myoblasts. Neonatal myoblast cells - Patient of developmental heart defect_exosome-Neonatal myoblast cells Protein Mass spectrometry 2012 - Microvesicles/Nanovesicles 468 23000592 Homo sapiens In-depth analysis of the secretome identifies three major independent secretory pathways in differentiating human myoblasts. Neonatal myoblast cells - Patient of developmental heart defect_microparticle-Neonatal myoblast cells Protein Mass spectrometry 2012 - Microvesicles/Nanovesicles 469 23029346 Echinostoma caproni Extracellular Vesicles from Parasitic Helminths Contain Specific Excretory/Secretory Proteins and Are Internalized in Intestinal Host Cells. Echinostoma caproni - Normal-Echinostoma caproni from ICR mice Protein Mass spectrometry 2012 - Exosomes/Extracellular vesicles/Microvesicles 470 23029346 Fasciola hepatica Extracellular Vesicles from Parasitic Helminths Contain Specific Excretory/Secretory Proteins and Are Internalized in Intestinal Host Cells. Fasciola hepatica - Normal-Fasciola hepatica from cow liver Protein Mass spectrometry 2012 - Exosomes/Extracellular vesicles/Microvesicles 471 23035643 Drosophila melanogaster Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes. Drosophila S2 cells - Normal-Drosophila S2 tub-Wg Protein Mass spectrometry 2012 - Exosomes 472 23043909 Pseudomonas syringae Virulence factors are released in association with outer membrane vesicles of Pseudomonas syringae pv. tomato T1 during normal growth. Pseudomonas syringae - Normal-Pseudomonas syringae pv tomato T1 Protein Mass spectrometry 2012 - Membrane vesicles 473 23056467 Homo sapiens Cause or Effect of Arteriogenesis: Compositional Alterations of Microparticles from CAD Patients Undergoing External Counterpulsation Therapy. Blood - Patients of external counterpulsation therapy-Blood Protein Mass spectrometry 2012 - Microparticles 474 23056502 Homo sapiens Identifying mRNA, MicroRNA and Protein Profiles of Melanoma Exosomes. Melanoma cells - Epidermal melanocytes (HEMa-LP) miRNA Microarray 2012 - Exosomes 475 23056502 Homo sapiens Identifying mRNA, MicroRNA and Protein Profiles of Melanoma Exosomes. Melanoma cells - Epidermal melanocytes (HEMa-LP) mRNA Microarray 2012 - Exosomes 476 23056502 Homo sapiens Identifying mRNA, MicroRNA and Protein Profiles of Melanoma Exosomes. Melanoma cells cl A375 miRNA Microarray 2012 - Exosomes 477 23056502 Homo sapiens Identifying mRNA, MicroRNA and Protein Profiles of Melanoma Exosomes. Melanoma cells cl A375 mRNA Microarray 2012 - Exosomes 478 23082778 Homo sapiens Comparative and Targeted Proteomic Analyses of Urinary Microparticles from Bladder Cancer and Hernia Patients. Urine ts Patients of bladder cancer-Urine Protein Mass spectrometry 2012 - Exosomes/Membrane vesicles 479 23082778 Homo sapiens Comparative and Targeted Proteomic Analyses of Urinary Microparticles from Bladder Cancer and Hernia Patients. Urine ts Patients of hernia-Urine Protein Mass spectrometry 2012 - Exosomes/Membrane vesicles 480 23161513 Homo sapiens Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS. Colorectal cancer cells cl DKO-1 Protein Mass spectrometry 2012 - Exosomes 481 23161513 Homo sapiens Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS. Colorectal cancer cells cl Dks-8 Protein Mass spectrometry 2012 - Exosomes 482 23161513 Homo sapiens Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS. Colorectal cancer cells cl DLD-1 Protein Mass spectrometry 2012 - Exosomes 483 23214914 Trypanosoma cruzi Proteomic analysis of Trypanosoma cruzi secretome: characterization of two populations of extracellular vesicles and soluble proteins. Epimastigotes - Normal_larger vesicles-Epimastigotes Protein Mass spectrometry 2012 - Exosomes/Extracellular vesicles/Ectosomes 484 23214914 Trypanosoma cruzi Proteomic analysis of Trypanosoma cruzi secretome: characterization of two populations of extracellular vesicles and soluble proteins. Epimastigotes - Normal_smaller vesicles-Epimastigotes Protein Mass spectrometry 2012 - Exosomes/Extracellular vesicles/Ectosomes 485 23214914 Trypanosoma cruzi Proteomic analysis of Trypanosoma cruzi secretome: characterization of two populations of extracellular vesicles and soluble proteins. Metacyclic trypomastigotes - Normal_larger vesicles-Metacyclic trypomastigotes Protein Mass spectrometry 2012 - Exosomes/Extracellular vesicles/Ectosomes 486 23230278 Homo sapiens Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids. Colorectal cancer cells cl A33 affinity purified exosomes-Colorectal cancer cells (LIM1863) Protein Mass spectrometry 2012 - Exosomes/Extracellular vesicles/Microvesicles 487 23230278 Homo sapiens Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids. Colorectal cancer cells cl EpCAM affinity purified exosomes-Colorectal cancer cells (LIM1863) Protein Mass spectrometry 2012 - Exosomes/Extracellular vesicles/Microvesicles 488 23230278 Homo sapiens Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids. Colorectal cancer cells cl Shed vesicles-Colorectal cancer cells (LIM1863) Protein Mass spectrometry 2012 - Exosomes/Extracellular vesicles/Microvesicles 489 23260141 Mus musculus Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration. Fibroblasts - Normal-Fibroblasts (L cells) Protein Mass spectrometry 2012 - Exosomes 490 23264574 Francisella novicida Production of Outer Membrane Vesicles and Outer Membrane Tubes by Francisella novicida. Francisella novicida - Normal_early stationary phase-Francisella novicida ATCC 15482 Protein Mass spectrometry 2012 - Membrane vesicles 491 23264574 Francisella novicida Production of Outer Membrane Vesicles and Outer Membrane Tubes by Francisella novicida. Francisella novicida - Normal_exponential phase-Francisella novicida ATCC 15482 Protein Mass spectrometry 2012 - Membrane vesicles 492 23333927 Homo sapiens Characterization and proteomic analysis of ovarian cancer-derived exosomes. Ovarian cancer cells cl IGROV1 Protein Mass spectrometry 2013 - Exosomes 493 23333927 Homo sapiens Characterization and proteomic analysis of ovarian cancer-derived exosomes. Ovarian cancer cells cl OVCAR-3 Protein Mass spectrometry 2013 - Exosomes 494 23344721 Homo sapiens miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles. Glioblastoma cells cl Primary glioblastoma multiforme cells (11/5) mRNA Microarray 2012 - Microvesicles 495 23344721 Homo sapiens miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles. Glioblastoma cells cl Primary glioblastoma multiforme cells (20/3) mRNA Microarray 2012 - Microvesicles 496 23344721 Homo sapiens miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles. Melanoma cells cl Primary malignant melanoma cells (0105) mRNA Microarray 2012 - Microvesicles 497 23344721 Homo sapiens miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles. Melanoma cells cl Primary malignant melanoma cells (0664) mRNA Microarray 2012 - Microvesicles 498 23376485 Homo sapiens Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. Urine ts Normal-Urine Protein Mass spectrometry 2013 - Exosomes/Membrane vesicles 499 23404715 Homo sapiens Distinct lipid compositions of two types of human prostasomes. Seminal fluid - 100 nm-Seminal fluid Lipids Liquid chromatography 2013 - Prostasomes 500 23404715 Homo sapiens Distinct lipid compositions of two types of human prostasomes. Seminal fluid - 50 nm-Seminal fluid Lipids Liquid chromatography 2013 - Prostasomes 501 23410224 Neisseria meningitidis Quantitative proteomics reveals distinct differences in the protein content of outer membrane vesicle vaccines. Neisseria meningitidis - Normal-Neisseria meningitidis H44/76 (serogroup B) Protein Mass spectrometry 2013 - Membrane vesicles 502 23436686 Homo sapiens A comprehensive characterization of membrane vesicles released by autophagic human endothelial cells. Endothelial cells - Serum-starved-Human umbilical vascular endothelial cells Protein Mass spectrometry 2013 - Membrane vesicles/Extracellular vesicles 503 23459212 Bos taurus Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis. Milk - Staphylococcus aureus-infected-Milk Protein Mass spectrometry 2013 - Exosomes 504 23465879 Homo sapiens Lipidomic analysis of human placental Syncytiotrophoblast microvesicles in adverse pregnancy outcomes. Placenta - Normal-Placental basal plate/decidua Lipids Mass spectrometry 2013 - Microvesicles 505 23465879 Homo sapiens Lipidomic analysis of human placental Syncytiotrophoblast microvesicles in adverse pregnancy outcomes. Placenta - Preeclampsia-Placental basal plate/decidua Lipids Mass spectrometry 2013 - Microvesicles 506 23465879 Homo sapiens Lipidomic analysis of human placental Syncytiotrophoblast microvesicles in adverse pregnancy outcomes. Placenta - Recurrent miscarriage-Placental basal plate/decidua Lipids Mass spectrometry 2013 - Microvesicles 507 23511837 Homo sapiens Differential protein profiling of renal cell carcinoma urinary exosomes. Urine ts Normal-Urine Protein Mass spectrometry 2013 - Exosomes/Nanovesicles 508 23511837 Homo sapiens Differential protein profiling of renal cell carcinoma urinary exosomes. Urine ts Renal cell carcinoma patient-Urine Protein Mass spectrometry 2013 - Exosomes/Nanovesicles 509 23521563 Homo sapiens First identification of Ewing's sarcoma-derived extracellular vesicles and exploration of their biological and potential diagnostic implications. Ewing's sarcoma cells cl A673 mRNA Microarray 2013 - Exosomes/Extracellular vesicles 510 23521563 Homo sapiens First identification of Ewing's sarcoma-derived extracellular vesicles and exploration of their biological and potential diagnostic implications. Ewing's sarcoma cells cl SB-KMS-KS1 mRNA Microarray 2013 - Exosomes/Extracellular vesicles 511 23521563 Homo sapiens First identification of Ewing's sarcoma-derived extracellular vesicles and exploration of their biological and potential diagnostic implications. Ewing's sarcoma cells cl SK-N-MC mRNA Microarray 2013 - Exosomes/Extracellular vesicles 512 23533145 Homo sapiens In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Urine - Low-grade prostate cancer patient-Expressed prostatic secretions in urine Protein Mass spectrometry 2013 - Exosomes/Microvesicles 513 23533145 Homo sapiens In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Urine - Normal-Expressed prostatic secretions in urine Protein Mass spectrometry 2013 - Exosomes/Microvesicles 514 23539611 Homo sapiens microRNA signature is altered in both human epididymis and seminal microvesicles following vasectomy. Seminal fluid - Normal-Seminal plasma miRNA Microarray 2013 - Microvesicles 515 23539611 Homo sapiens microRNA signature is altered in both human epididymis and seminal microvesicles following vasectomy. Seminal fluid - Vasectomy-Seminal plasma miRNA Microarray 2013 - Microvesicles 516 23539611 Homo sapiens microRNA signature is altered in both human epididymis and seminal microvesicles following vasectomy. Seminal fluid - Vasovasostomy-Seminal plasma miRNA Microarray 2013 - Microvesicles 517 23585443 Homo sapiens Proteome profiling of exosomes derived from human primary and metastatic colorectal cells reveal differential expression of key metastatic factors and signal transduction components. Colorectal cancer cells - SW480 Protein Mass spectrometry 2013 - Exosomes/Membrane vesicles 518 23585443 Homo sapiens Proteome profiling of exosomes derived from human primary and metastatic colorectal cells reveal differential expression of key metastatic factors and signal transduction components. Colorectal cancer cells - SW620 Protein Mass spectrometry 2013 - Exosomes/Membrane vesicles 519 23585444 Homo sapiens Identification and characterization of proteins isolated from microvesicles derived from human lung cancer pleural effusions. Malignant pleural effusions - Non-small cell lung cancer patient-Lung cancer pleural effusion Protein Mass spectrometry 2013 - Exosomes/Microvesicles/Ectosomes/Microparticles 520 23601281 Homo sapiens Proteomic characterization of human platelet-derived microparticles. Blood - Normal-Blood Protein Mass spectrometry 2013 - Microparticles 521 23645497 Canis lupus familiaris Oncogenic H-Ras reprograms Madin-Darby canine kidney (MDCK) cell-derived exosomal proteins following epithelial-mesenchymal transition. Madin-Darby canine kidney cell (MDCK) - Normal-Madin-Darby canine kidney cell (MDCK) Protein Mass spectrometry 2013 - Exosomes/Extracellular vesicles 522 23645497 Canis lupus familiaris Oncogenic H-Ras reprograms Madin-Darby canine kidney (MDCK) cell-derived exosomal proteins following epithelial-mesenchymal transition. Madin-Darby canine kidney cell (MDCK) - Ras-transformed MDCK cells (21D1) Protein Mass spectrometry 2013 - Exosomes/Extracellular vesicles 523 23658846 Mus musculus Immunomodulatory impact of leishmania-induced macrophage exosomes: a comparative proteomic and functional analysis. Macrophages - Leishmania-infected-Macrophage (J774A.1) Protein Mass spectrometry 2013 - Exosomes 524 23658846 Mus musculus Immunomodulatory impact of leishmania-induced macrophage exosomes: a comparative proteomic and functional analysis. Macrophages - LPS-treated-Macrophage (J774A.1) Protein Mass spectrometry 2013 - Exosomes 525 23658846 Mus musculus Immunomodulatory impact of leishmania-induced macrophage exosomes: a comparative proteomic and functional analysis. Macrophages - Normal-Macrophage (J774A.1) Protein Mass spectrometry 2013 - Exosomes 526 23660474 Homo sapiens Heterogeneity in neutrophil microparticles reveals distinct proteome and functional properties. Neutrophils - Stimulated in fluid phase-Neutrophil Protein Mass spectrometry 2013 - Microparticles 527 23660474 Homo sapiens Heterogeneity in neutrophil microparticles reveals distinct proteome and functional properties. Neutrophils - Stimulated in immobile phase-Neutrophil Protein Mass spectrometry 2013 - Microparticles 528 23767874 Homo sapiens Biochemical and biological characterization of exosomes containing prominin-1/CD133. Melanoma cells - Malignant melanoma (FEMX-I) Lipids Mass spectrometry 2013 - Exosomes/Microvesicles 529 23786572 Homo sapiens Phospholipidomics of Human Blood Microparticles. Blood - Normal-Blood Lipids Mass spectrometry 2013 - Microparticles 530 23803555 Bos taurus Epididymosomes Convey Different Repertoires of MicroRNAs Throughout the Bovine Epididymis. Epithelial cells - Normal-Caput epithelial cells miRNA Microarray 2013 - Membrane vesicles 531 23803555 Bos taurus Epididymosomes Convey Different Repertoires of MicroRNAs Throughout the Bovine Epididymis. Caput luminal fluid - Normal-Caput luminal fluid miRNA Microarray 2013 - Membrane vesicles 532 23803555 Bos taurus Epididymosomes Convey Different Repertoires of MicroRNAs Throughout the Bovine Epididymis. Epithelial cells - Normal-Cauda epithelial cells miRNA Microarray 2013 - Membrane vesicles 533 23803555 Bos taurus Epididymosomes Convey Different Repertoires of MicroRNAs Throughout the Bovine Epididymis. Cauda luminal fluid - Normal-Cauda luminal fluid miRNA Microarray 2013 - Membrane vesicles 534 23818640 Homo sapiens Modulation of B-cell exosome proteins by gamma herpesvirus infection. B cells - EBV- and KSHV-infected B cells (JSC-1, BC1) Protein Mass spectrometry 2013 - Exosomes/Microvesicles/Oncosomes/Microparticles 535 23818640 Homo sapiens Modulation of B-cell exosome proteins by gamma herpesvirus infection. B cells - EBV-infected B cells (#1, HLJ, IM9, CP) Protein Mass spectrometry 2013 - Exosomes/Microvesicles/Oncosomes/Microparticles 536 23818640 Homo sapiens Modulation of B-cell exosome proteins by gamma herpesvirus infection. B cells - KSHV-infected B cell (JC, BC3, BCP1, BCBL1) Protein Mass spectrometry 2013 - Exosomes/Microvesicles/Oncosomes/Microparticles 537 23818640 Homo sapiens Modulation of B-cell exosome proteins by gamma herpesvirus infection. B cells - Normal B cells (BJAB) Protein Mass spectrometry 2013 - Exosomes/Microvesicles/Oncosomes/Microparticles 538 23844026 Homo sapiens Characterization of human thymic exosomes. Thymus - Normal-Thymus Protein Mass spectrometry 2013 - Exosomes 539 23853596 Trichomonas vaginalis Trichomonas vaginalis Exosomes Deliver Cargo to Host Cells and Mediate Host∶Parasite Interactions. Trichomonas vaginalis - Normal-Trichomonas vaginalis B7RC2 Protein Mass spectrometry 2013 - Exosomes/Microvesicles 540 23886663 Homo sapiens LRRK2 Secretion in Exosomes is Regulated by 14-3-3. Urine ts Normal-Urine Protein Mass spectrometry 2013 - Exosomes/Microvesicles 541 23935504 Homo sapiens A Novel Role for Pro-Coagulant Microvesicles in the Early Host Defense against Streptococcus pyogenes. Peripheral blood mononucelar cells - Normal-Peripheral blood mononucelar cells Protein Mass spectrometry 2013 - Microvesicles 542 23935504 Homo sapiens A Novel Role for Pro-Coagulant Microvesicles in the Early Host Defense against Streptococcus pyogenes. Peripheral blood mononucelar cells - Procoagulant (M1 protein-treated)-Peripheral blood mononucelar cells Protein Mass spectrometry 2013 - Microvesicles 543 23977379 Listeria monocytogenes Transcription Factor σ(B) Plays an Important Role in the Production of Extracellular Membrane-Derived Vesicles in Listeria monocytogenes. Listeria monocytogenes - Normal-Listeria monocytogenes 10403S (wild-type) Protein Mass spectrometry 2013 - Membrane vesicles 544 23977379 Listeria monocytogenes Transcription Factor σ(B) Plays an Important Role in the Production of Extracellular Membrane-Derived Vesicles in Listeria monocytogenes. Listeria monocytogenes - Normal-Listeria monocytogenes 10403S (ΔsigB mutant) Protein Mass spectrometry 2013 - Membrane vesicles 545 23983189 Homo sapiens Characterization of Multiple Myeloma Vesicles by Label-Free Relative Quantitation. B cells cl MM.1S Protein Mass spectrometry 2013 - Exosomes/Extracellular vesicles/Microvesicles 546 23983189 Homo sapiens Characterization of Multiple Myeloma Vesicles by Label-Free Relative Quantitation. B cells cl U266 Protein Mass spectrometry 2013 - Exosomes/Extracellular vesicles/Microvesicles 547 24009880 Homo sapiens Characterization of mRNA and microRNA in human mast cell-derived exosomes and their transfer to other mast cells and blood CD34 progenitor cells. Mast cells cl HMC-1 miRNA Microarray 2012 - Exosomes/Extracellular vesicles 548 24009880 Homo sapiens Characterization of mRNA and microRNA in human mast cell-derived exosomes and their transfer to other mast cells and blood CD34 progenitor cells. Mast cells cl HMC1 mRNA Microarray 2012 - Exosomes/Extracellular vesicles 549 24009881 Homo sapiens Quantitative proteomics of extracellular vesicles derived from human primary and metastatic colorectal cancer cells. Colorectal cancer cells cl SW480 Protein Mass spectrometry 2012 - Exosomes/Extracellular vesicles/Microvesicles/Ectosomes 550 24009881 Homo sapiens Quantitative proteomics of extracellular vesicles derived from human primary and metastatic colorectal cancer cells. Colorectal cancer cells cl SW620 Protein Mass spectrometry 2012 - Exosomes/Extracellular vesicles/Microvesicles/Ectosomes 551 24009886 Homo sapiens Cellular stress conditions are reflected in the protein and RNA content of endothelial cell-derived exosomes. Endothelial cells cl Stressed (hypoxia, TNF-alpha-induced activation, high glucose and mannose concentrations)-Endothelial cells (HMEC-1) Protein Mass spectrometry 2012 - Exosomes/Extracellular vesicles 552 24009898 Mus musculus Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes. Cardiomyocyte cells cl Cardiomyocyte cells (HL-1) mRNA Microarray 2013 - Exosomes/Extracellular vesicles 553 24009898 Mus musculus Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes. Cardiomyocyte cells cl PDGFBβ-treated-Cardiomyocyte cells (HL-1) mRNA Microarray 2013 - Exosomes/Extracellular vesicles 554 24009898 Mus musculus Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes. Cardiomyocyte cells cl TGFβ-treated-Cardiomyocyte cells (HL-1) mRNA Microarray 2013 - Exosomes/Extracellular vesicles 555 24046871 Homo sapiens Molecular lipidomics of exosomes released by PC-3 prostate cancer cells. Prostate cancer cells cl PC3 Lipids Mass spectrometry 2013 - Exosomes/Microvesicles 556 24069378 Homo sapiens Proteome profiling of neuroblastoma-derived exosomes reveal the expression of proteins potentially involved in tumor progression. Neuroblastoma cells cl HTLA-230 Protein Mass spectrometry 2013 - Exosomes/Membrane vesicles 559 26098775 Citrus Limon L. Citrus limon-derived nanovesicles inhibit cancer cell proliferation and suppress CML xenograft growth by inducing TRAIL-mediated cell death Lemon juice ts Lemon juice Protein Mass spectrometry [TripleTOF System] 2015 Differential centrifugation|Ultracenrifugation Nanovesicles 562 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells ts monocyte-derived dendritic cells (F3 10K) Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Ultracenrifugation|OptiPrep density gradient Microvesicles 563 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells ts monocyte-derived dendritic cells (F5 10K) Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Ultracenrifugation|OptiPrep density gradient Microvesicles 564 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells ts monocyte-derived dendritic cells (F3 100K) Protein Mass spectrometry [LTQ] 2016 Differential centrifugation|Ultracenrifugation|OptiPrep density gradient Exosomes 565 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells ts monocyte-derived dendritic cells (F5 100K) Protein Mass spectrometry [LTQ ORBITRAP] 2016 Differential centrifugation|Ultracenrifugation|OptiPrep density gradient Exosomes 566 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells ts monocyte-derived dendritic cells (Igg1 PD) Protein Mass spectrometry [LTQ FUSION] 2016 Differential centrifugation|Ultracenrifugation|Immunobeads (Igg1 PD) Extracellular vesicle 567 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells ts monocyte-derived dendritic cells (Igg1 FT) Protein Mass spectrometry [LTQ FUSION] 2016 Differential centrifugation|Ultracenrifugation|Immunobeads (Igg1 FT) Extracellular vesicle 568 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells ts monocyte-derived dendritic cells (CD9 PD) Protein Mass spectrometry [LTQ FUSION] 2016 Differential centrifugation|Ultracenrifugation|Immunobeads (CD9 PD) Extracellular vesicle 569 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells ts monocyte-derived dendritic cells (CD9 FT) Protein Mass spectrometry [LTQ FUSION] 2016 Differential centrifugation|Ultracenrifugation|Immunobeads (CD9 FT) Extracellular vesicle 570 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells ts monocyte-derived dendritic cells (CD63 PD) Protein Mass spectrometry [LTQ FUSION] 2016 Differential centrifugation|Ultracenrifugation|Immunobeads (CD63 PD) Extracellular vesicle 571 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells ts monocyte-derived dendritic cells (CD63 FT) Protein Mass spectrometry [LTQ FUSION] 2016 Differential centrifugation|Ultracenrifugation|Immunobeads (CD63 FT) Extracellular vesicle 572 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells ts monocyte-derived dendritic cells (CD81 PD) Protein Mass spectrometry [LTQ FUSION] 2016 Differential centrifugation|Ultracenrifugation|Immunobeads (CD81 PD) Extracellular vesicle 573 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells ts monocyte-derived dendritic cells (CD81 FT) Protein Mass spectrometry [LTQ FUSION] 2016 Differential centrifugation|Ultracenrifugation|Immunobeads (CD81 FT) Extracellular vesicle 574 27601599 Homo sapiens Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components Breast milk ts Breast milk - normal Protein Mass spectrometry 2016 Differential centrifugation|Ultracentrifugation|Sucrose density gradient Extracellular vesicles 575 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Breast cancer cells cl BT549 Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 576 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Breast cancer cells cl HS 578T Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 577 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Breast cancer cells cl MCF7 Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 578 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Breast cancer cells cl MDA-MB-231 Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 579 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Breast cancer cells cl MDA-MB-468 Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 580 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Brain cancer cells cl T-47D Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 581 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Brain cancer cells cl SF268 Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 582 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Brain cancer cells cl SF295 Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 583 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Brain cancer cells cl SF539 Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 584 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Brain cancer cells cl SNB-19 Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 585 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Brain cancer cells cl SNB-75 Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 586 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Brain cancer cells cl U251 Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 587 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Colon cancer cells cl Colo205 Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 588 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Colon cancer cells cl HCC 2998 Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 589 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Colon cancer cells cl HCT-116 Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 590 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Colon cancer cells cl HCT-15 Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 591 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Colon cancer cells cl HT29 Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 592 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Colon cancer cells cl KM12 Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 593 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Colon cancer cells cl SW620 Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 594 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Kidney cancer cells cl 786-O Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 595 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Kidney cancer cells cl A498 Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 596 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Kidney cancer cells cl ACHN Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 597 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Kidney cancer cells cl CAKI Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 598 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Kidney cancer cells cl RXF 393 Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 599 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Kidney cancer cells cl SN12C Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 600 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Kidney cancer cells cl TK-10 Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 601 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Kidney cancer cells cl UO-31 Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 602 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Leukemia cells cl CCRF-CEM Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 603 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Leukemia cells cl HL-60 Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 604 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Leukemia cells cl K562 Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 605 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Leukemia cells cl MOLT-4 Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 606 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Leukemia cells cl RPMI-8226 Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 607 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Leukemia cells cl SR Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 608 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Lung cancer cells cl A549 Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 609 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Lung cancer cells cl EKVX Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 610 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Lung cancer cells cl HOP-62 Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 611 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Lung cancer cells cl HOP-92 Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 612 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Lung cancer cells cl NCI-H226 Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 613 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Lung cancer cells cl NCI-H23 Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 614 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Lung cancer cells cl NCI-H322M Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 615 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Lung cancer cells cl NCI-H460 Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 616 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Lung cancer cells cl NCI-H522 Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 617 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Melanoma cells cl LOX IMVI Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 618 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Melanoma cells cl M14 Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 619 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Melanoma cells cl MALME-3M Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 620 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Melanoma cells cl MDA-MB-435 Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 621 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Melanoma cells cl SK-MEL-2 Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 622 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Melanoma cells cl SK-MEL-28 Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 623 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Melanoma cells cl SK-MEL-5 Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 624 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Melanoma cells cl UACC-257 Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 625 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Melanoma cells cl UACC-62 Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 626 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Ovarian cancer cells cl IGROV1 Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 627 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Ovarian cancer cells cl OVCAR-3 Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 628 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Ovarian cancer cells cl OVCAR-4 Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 629 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Ovarian cancer cells cl OVCAR-5 Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 630 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Ovarian cancer cells cl OVCAR-8 Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 631 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Ovarian cancer cells cl SK-OV-3 Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 632 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Ovarian cancer cells cl NCI-ADR-RES Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 633 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Prostate cancer cells cl DU145 Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles 634 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Prostate cancer cells cl PC-3 Protein Mass spectrometry [LTQ] 2016 Serum-free medium|Differential centrifugation|polymer-based precipitation|Ultracenrifugation Extracellular vesicles