Browse results for vesicle type: Exosomes

	Vesiclepedia ID	PubMed ID	Species	Experiment description	Sample	Identifications	Isolation methods	Vesicle type
1	Vesiclepedia_1261	24371517	Homo sapiens	Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
2	Vesiclepedia_1119	24391718	Homo sapiens	Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
3	Vesiclepedia_1101	24513287	Mus musculus	Lipid synthesis is promoted by hypoxic adipocyte-derived exosomes in 3T3-L1 cells.	Serum	Protein	Differential centrifugation Ultracentrifugation Filtration	Exosomes
4	Vesiclepedia_48	17641064	Homo sapiens	Exosomes with immune modulatory features are present in human breast milk.	Breast milk	Protein	Differential centrifugation Filtration Sucrose density gradient	Exosomes
5	Vesiclepedia_1283	22345510	Rattus norvegicus	Characterization of membrane-shed microvesicles from cytokine-stimulated .-cells using proteomics strategies.	Insulinoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
6	Vesiclepedia_94	21828046	Rattus norvegicus	The proteo-lipidic composition of exosomes changes during reticulocyte maturation.	Reticulocytes	Protein Lipids	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
7	Vesiclepedia_1001	24079734	Mus musculus	Immunostimulatory activity of murine keratinocyte-derived exosomes.	Keratinocytes	Protein	Differential centrifugation Ultracentrifugation	Exosomes
8	Vesiclepedia_1053	29115712	Mus musculus	Proteomic Profiling of Exosomes Secreted by Breast Cancer Cells with Varying Metastatic Potential.	Breast cancer cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
9	Vesiclepedia_20	17956143	Homo sapiens	Proteomic analysis of microvesicles derived from human colorectal cancer cells.	Colorectal cancer cells	Protein	Differential centrifugation Sucrose density gradient Diafiltration	Exosomes
10	Vesiclepedia_1051	29115712	Mus musculus	Proteomic Profiling of Exosomes Secreted by Breast Cancer Cells with Varying Metastatic Potential.	Breast cancer cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
11	Vesiclepedia_552	24009898	Mus musculus	Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.	Cardiomyocytes	mRNA	-	Exosomes/Extracellular vesicles
12	Vesiclepedia_781	29953723	Salmo salar	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Leukocytes	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
13	Vesiclepedia_40	15908444	Homo sapiens	Exosomal-like vesicles are present in human blood plasma.	Plasma	Protein	Differential centrifugation Filtration Sucrose density gradient	Exosomes
14	Vesiclepedia_1141	23454749	Homo sapiens	BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression.	Bone marrow mesenchymal stromal cells	Protein	Differential centrifugation Ultracentrifugation Filtration ExoQuick	Exosomes
15	Vesiclepedia_1220	27872147	Rattus norvegicus	Primary Human and Rat .-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity.	Insulinoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
16	Vesiclepedia_790	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Embryonic kidney cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
17	Vesiclepedia_758	28357077	Mus musculus	Circulating osteocyte-derived exosomes contain miRNAs which are enriched in exosomes from MLO-Y4 cells	Osteocytes	miRNA	Total Exosome Isolation Kit Differential centrifugation	Exosomes
18	Vesiclepedia_1237	25421927	Heligmosomoides polygyrus	Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity.	Heligmosomoides polygyrus	miRNA Protein	Filtration Ultracentrifugation	Exosomes
19	Vesiclepedia_4	11487543	Homo sapiens	Intestinal epithelial cells secrete exosome-like vesicles.	Epithelial cells	Protein	Differential centrifugation Sucrose density gradient	Exosomes
20	Vesiclepedia_1108	24391718	Homo sapiens	Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.	Prostate epithelial cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
21	Vesiclepedia_676	29951053	Mus musculus	Immunoregulatory Effects of Myeloid-Derived Suppressor Cell Exosomes in Mouse Model of Autoimmune Alopecia Areata.	Myeloid-derived suppressor cells	Protein	Ultracentrifugation Density gradient centrifugation	Exosomes
22	Vesiclepedia_665	29956871	Homo sapiens	Expression analysis of extracellular microRNA in bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis	Bronchoalveolar lavage fluid	miRNA	Differential centrifugation Ultracentrifugation Filtration	Exosomes
23	Vesiclepedia_512	23533145	Homo sapiens	In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.	Urine	Protein	-	Exosomes/Microvesicles
24	Vesiclepedia_903	25053844	Homo sapiens	Activity-associated miRNA are packaged in Map1b-enriched exosomes released from depolarized neurons	Neuroblastoma cells	Protein	Differential centrifugation Ultracentrifugation Filtration	Exosomes
25	Vesiclepedia_1215	27872147	Rattus norvegicus	Primary Human and Rat .-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity.	Islets	Protein	Differential centrifugation Ultracentrifugation	Exosomes
26	Vesiclepedia_832	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Differential centrifugation Filtration ExoQuick Ultracentrifugation	Exosomes
27	Vesiclepedia_1159	20409149	Homo sapiens	Transdifferentiated circulating monocytes release exosomes containing 14-3-3 proteins with matrix metalloproteinase-1 stimulating effect for dermal fibroblasts.	Keratinocytes	Protein	Differential centrifugation Filtration Ultrafiltration Ultracentrifugation Sucrose density gradient	Exosomes
28	Vesiclepedia_834	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Differential centrifugation Filtration ExoQuick Ultracentrifugation	Exosomes
29	Vesiclepedia_470	23029346	Fasciola hepatica	Extracellular Vesicles from Parasitic Helminths Contain Specific Excretory/Secretory Proteins and Are Internalized in Intestinal Host Cells.	Fasciola hepatica	Protein	-	Exosomes/Extracellular vesicles/Microvesicles
30	Vesiclepedia_1013	22711894	Homo sapiens	Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages.	Macrophages	Protein Lipids	Differential centrifugation Filtration Ultracentrifugation	Exosomes
31	Vesiclepedia_663	29956871	Homo sapiens	Expression analysis of extracellular microRNA in bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis	Bronchoalveolar lavage fluid	Protein	Differential centrifugation Ultracentrifugation Filtration	Exosomes
32	Vesiclepedia_671	29953960	Homo sapiens	Exosomes derived from calcium oxalate-exposed macrophages enhance IL-8 production from renal cells, neutrophil migration and crystal invasion through extracellular matrix.	Macrophages	Protein	Microfiltration Differential centrifugation Ultracentrifugation	Exosomes
33	Vesiclepedia_1256	24400796	Homo sapiens	Exosomal proteins in the aqueous humor as novel biomarkers in patients with neovascular age-related macular degeneration.	Retinal pigment epithelial cells	Protein	ExoQuick	Exosomes
34	Vesiclepedia_1276	23344851	Rattus norvegicus	Urinary exosomes and diabetic nephropathy: a proteomic approach.	Urine	Protein	Ultracentrifugation	Exosomes
35	Vesiclepedia_657	28753793	Homo sapiens	MicroRNAs in Serum Exosomes as Potential Biomarkers in Clear-cell Renal Cell Carcinoma.	Serum	miRNA	Total Exosome Isolation Kit Differential centrifugation Ultracentrifugation Immunobeads (EpCAM)	Exosomes
36	Vesiclepedia_986	25261472	Homo sapiens	Complex N-linked glycans serve as a determinant for exosome/microvesicle cargo recruitment.	Melanoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes/Microvesicles
37	Vesiclepedia_653	28290293	Homo sapiens	Comparative proteomic analysis of milk-derived exosomes in human and bovine colostrum and mature milk samples by iTRAQ-coupled LC-MS/MS.	Breast milk	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Exosomes
38	Vesiclepedia_1245	25167841	Homo sapiens	Antibody-coupled monolithic silica microtips for highthroughput molecular profiling of circulating exosomes.	Serum	Protein	CD9 antibody to Mass Spectrometric Immunoassay monolith pipette tips	Exosomes
39	Vesiclepedia_399	19530224	Homo sapiens	Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes.	Keratinocytes	Protein	-	Exosomes
40	Vesiclepedia_503	23459212	Bos taurus	Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.	Bovine milk	Protein	-	Exosomes
41	Vesiclepedia_824	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Filtration Ultracentrifugation Sucrose density gradient	Exosomes
42	Vesiclepedia_547	24009880	Homo sapiens	Characterization of mRNA and microRNA in human mast cell-derived exosomes and their transfer to other mast cells and blood CD34 progenitor cells.	Mast cells	miRNA	-	Exosomes/Extracellular vesicles
43	Vesiclepedia_550	24009881	Homo sapiens	Quantitative proteomics of extracellular vesicles derived from human primary and metastatic colorectal cancer cells.	Colorectal cancer cells	Protein	-	Exosomes/Extracellular vesicles/Microvesicles/Ectosomes
44	Vesiclepedia_922	25483805	Homo sapiens	Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties	Embryonic kidney cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
45	Vesiclepedia_861	25776846	Homo sapiens	Human thymic epithelial primary cells produce exosomes carrying tissue-restricted antigens	Epithelial cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
46	Vesiclepedia_138	22723089	Homo sapiens	Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes.	Prostate cancer cells	Protein	Sucrose density gradient	Exosomes
47	Vesiclepedia_1120	24347249	Homo sapiens	Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation ExoQuick	Exosomes
48	Vesiclepedia_720	26148937	Homo sapiens	Proteomics profiling of cholangiocarcinoma exosomes: A potential role of oncogenic protein transferring in cancer progression.	Cholangiocytes	Protein	Differential centrifugation Ultracentrifugation Filtration	Exosomes
49	Vesiclepedia_998	24355714	Homo sapiens	Proteomic analysis and immune properties of exosomes released by macrophages infected with Mycobacterium avium.	Leukemia cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
50	Vesiclepedia_981	25458527	Homo sapiens	Benchtop isolation and characterization of functional exosomes by sequential filtration	Breast cancer cells	Protein	Sequential filtration	Exosomes
51	Vesiclepedia_925	25483805	Homo sapiens	Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties	Embryonic kidney cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
52	Vesiclepedia_1078	25104112	Homo sapiens	Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy.	Plasma	miRNA	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Exosomes
53	Vesiclepedia_1204	27780738	Homo sapiens	Next-generation sequencing-based small RNA profiling of cerebrospinal fluid exosomes.	Serum	miRNA	Differential centrifugation Ultracentrifugation	Exosomes
54	Vesiclepedia_990	25261472	Homo sapiens	Complex N-linked glycans serve as a determinant for exosome/microvesicle cargo recruitment.	Melanoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes/Microvesicles
55	Vesiclepedia_1236	25421927	Heligmosomoides polygyrus	Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity.	Heligmosomoides polygyrus	miRNA Protein	Filtration Ultracentrifugation	Exosomes
56	Vesiclepedia_1291	19912576	Homo sapiens	HIV Nef is secreted in exosomes and triggers apoptosis in bystander CD4+ T cells.	Lymphoblasts	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
57	Vesiclepedia_86	20949044	Homo sapiens	Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line	Colorectal cancer cells	miRNA	Differential centrifugation Filtration Ultracentrifugation	Exosomes
58	Vesiclepedia_18	11907077	Homo sapiens	TCR activation of human T cells induces the production of exosomes bearing the TCR/CD3/zeta complex.	T cells	Protein	Filtration Ultracentrifugation	Exosomes
59	Vesiclepedia_896	26100252	Homo sapiens	Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts	Chronic lymphocytic leukemia cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
60	Vesiclepedia_969	25844599	Homo sapiens	Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.	Serum	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
61	Vesiclepedia_742	28524762	Rattus norvegicus	Exosomes promote restoration after an experimental animal model of intracerebral hemorrhage	Mesenchymal stem cells	Protein	miRCURY Exosome Isolation Kit	Exosomes
62	Vesiclepedia_72	19801663	Homo sapiens	Microenvironmental pH is a key factor for exosome traffic in tumor cells.	Melanoma cells	Protein Lipids	Differential centrifugation	Exosomes
63	Vesiclepedia_510	23521563	Homo sapiens	First identification of Ewing's sarcoma-derived extracellular vesicles and exploration of their biological and potential diagnostic implications.	Ewing's sarcoma cells	mRNA	-	Exosomes/Extracellular vesicles
64	Vesiclepedia_24	11231627	Homo sapiens	Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming.	Melanoma cells	Protein	Differential centrifugation Sucrose density gradient	Exosomes
65	Vesiclepedia_1147	23173708	Rattus norvegicus	Wnt3a induces exosome secretion from primary cultured rat microglia.	Primary microglial cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
66	Vesiclepedia_1	6307529	Ovis aries	Fate of the transferrin receptor during maturation of sheep reticulocytes in vitro: selective externalization of the receptor.	Reticulocytes	Protein	-	Exosomes
67	Vesiclepedia_879	29955024	Homo sapiens	Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells	Myeloid leukemia cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
68	Vesiclepedia_81	20458337	Homo sapiens	MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 3	B cells	Protein	Differential centrifugation Sucrose density gradient Immunobeads (MHC Class II)	Exosomes
69	Vesiclepedia_335	20976003	Homo sapiens	Selective release of microRNA species from normal and malignant mammary epithelial cells	Breast cancer cells	Protein miRNA	Differential centrifugation Filtration	Exosomes
70	Vesiclepedia_332	19627513	Homo sapiens	Exosomes from human saliva as a source of microRNA biomarkers	Saliva	miRNA	Differential centrifugation Ultracentrifugation	Exosomes
71	Vesiclepedia_471	23035643	Drosophila melanogaster	Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.	Drosophila S2 cells	Protein	-	Exosomes
72	Vesiclepedia_883	29955024	Homo sapiens	Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells	Myeloid leukemia cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
73	Vesiclepedia_323	20304794	Homo sapiens	Functional delivery of viral miRNAs via exosomes	B cells	Protein	Differential centrifugation	Exosomes
74	Vesiclepedia_813	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Differential centrifugation Filtration ExoQuick Ultracentrifugation	Exosomes
75	Vesiclepedia_535	23818640	Homo sapiens	Modulation of B-cell exosome proteins by gamma herpesvirus infection.	B cells	Protein	-	Exosomes/Microvesicles/Oncosomes/Microparticles
76	Vesiclepedia_277	22030351	Homo sapiens	Expression of PTRF in PC-3 cells modulates cholesterol dynamics and the actin cytoskeleton impacting secretion pathways	Prostate cancer cells	Protein	Differential centrifugation	Exosomes
77	Vesiclepedia_83	20949044	Homo sapiens	Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line	Lung cancer cells	Protein miRNA	Differential centrifugation Filtration Ultracentrifugation	Exosomes
78	Vesiclepedia_757	28357077	Mus musculus	Circulating osteocyte-derived exosomes contain miRNAs which are enriched in exosomes from MLO-Y4 cells	Plasma	miRNA	Total Exosome Isolation Kit Differential centrifugation	Exosomes
79	Vesiclepedia_1250	24939845	Homo sapiens	Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein.	Leukemia cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
80	Vesiclepedia_913	28687758	Sus scrofa	Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers	Polarised retinal pigmented epithelial cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
81	Vesiclepedia_710	28811610	Homo sapiens	Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA.	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
82	Vesiclepedia_1152	22057275	Homo sapiens	Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease.	Neuroblastoma cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
83	Vesiclepedia_82	20949044	Homo sapiens	Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line	Stomach cancer cells	Protein miRNA	Differential centrifugation Filtration Ultracentrifugation	Exosomes
84	Vesiclepedia_61	17133577	Mus musculus	Association of citrullinated proteins with synovial exosomes.	Synovial fluid	Protein	Differential centrifugation Sucrose density gradient	Exosomes
85	Vesiclepedia_41	15908444	Homo sapiens	Exosomal-like vesicles are present in human blood plasma.	Mast cells	Protein	Differential centrifugation Filtration Sucrose density gradient	Exosomes
86	Vesiclepedia_1263	24371517	Homo sapiens	Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients.	Urine	Protein	Differential centrifugation Ultracentrifugation	Exosomes
87	Vesiclepedia_897	26100252	Homo sapiens	Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts	Chronic lymphocytic leukemia cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
88	Vesiclepedia_343	22965126	Mus musculus	Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells.	Neuronal cells	miRNA	Differential centrifugation Filtration Ultracentrifugation	Exosomes
89	Vesiclepedia_741	25157233	Homo sapiens	Extravillous trophoblast cells-derived exosomes promote vascular smooth muscle cell migration.	Placenta	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
90	Vesiclepedia_344	22965126	Mus musculus	Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells.	Neuronal cells	miRNA	Differential centrifugation Filtration Ultracentrifugation	Exosomes
91	Vesiclepedia_1016	22711894	Homo sapiens	Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages.	Macrophages	Protein Lipids	Differential centrifugation Filtration Ultracentrifugation	Exosomes
92	Vesiclepedia_392	19351151	Mus musculus	Characterization of vesicles secreted from insulinoma NIT-1 cells.	Pancreatic cells	Protein	-	Exosomes
93	Vesiclepedia_108	21601258	Homo sapiens	Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage.	Ascites	Protein miRNA	Differential centrifugation Sucrose density gradient Immunobeads (EpCAM, CD24)	Exosomes
94	Vesiclepedia_79	20458337	Homo sapiens	MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 1	B cells	Protein	Differential centrifugation Sucrose density gradient Immunobeads (MHC Class II)	Exosomes
95	Vesiclepedia_719	26148937	Homo sapiens	Proteomics profiling of cholangiocarcinoma exosomes: A potential role of oncogenic protein transferring in cancer progression.	Cholangiocarcinoma cells	Protein	Differential centrifugation Ultracentrifugation Filtration	Exosomes
96	Vesiclepedia_763	29953723	Salmo salar	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Leukocytes	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
97	Vesiclepedia_1093	25065644	Homo sapiens	Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells.	Duodenal cancer cells	Protein	Differential centrifugation Filtration Ultrafiltration	Exosomes
98	Vesiclepedia_1199	27883272	Homo sapiens	Circulating adipocyte-derived exosomal MicroRNAs associated with decreased insulin resistance after gastric bypass.	Serum	miRNA Metabolites	ExoQuick	Exosomes
99	Vesiclepedia_1244	25167841	Homo sapiens	Antibody-coupled monolithic silica microtips for highthroughput molecular profiling of circulating exosomes.	Serum	Protein	CD9 antibody to Mass Spectrometric Immunoassay monolith pipette tips	Exosomes
100	Vesiclepedia_768	29953723	Salmo salar	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Leukocytes	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
101	Vesiclepedia_539	23853596	Trichomonas vaginalis	Trichomonas vaginalis Exosomes Deliver Cargo to Host Cells and Mediate Host∶Parasite Interactions.	Trichomonas vaginalis	Protein	-	Exosomes/Microvesicles
102	Vesiclepedia_738	25157233	Homo sapiens	Extravillous trophoblast cells-derived exosomes promote vascular smooth muscle cell migration.	Placenta choriocarcinoma cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
103	Vesiclepedia_436	22031862	Mus musculus	Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes.	Dendritic cells	miRNA	-	Exosomes/Nanovesicles
104	Vesiclepedia_555	24046871	Homo sapiens	Molecular lipidomics of exosomes released by PC-3 prostate cancer cells.	Prostate cancer cells	Lipids	-	Exosomes/Microvesicles
105	Vesiclepedia_724	25471207	Homo sapiens	Intraluminal proteome and peptidome of human urinary extracellular vesicles.	Urine	Protein	Differential centrifugation Hydrostatic filtration dialysis Ultrafiltration	Exosomes
106	Vesiclepedia_388	18570454	Homo sapiens	Proteomic analysis of exosomes from human neural stem cells by flow field-flow fractionation and nanoflow liquid chromatography-tandem mass spectrometry.	Neural stem cells	Protein	-	Exosomes/Membrane vesicles
107	Vesiclepedia_798	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Embryonic kidney cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
108	Vesiclepedia_486	23230278	Homo sapiens	Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids.	Colorectal cancer cells	Protein	-	Exosomes/Extracellular vesicles/Microvesicles
109	Vesiclepedia_904	25053844	Homo sapiens	Activity-associated miRNA are packaged in Map1b-enriched exosomes released from depolarized neurons	Neuroblastoma cells	miRNA	Differential centrifugation Ultracentrifugation Filtration	Exosomes
110	Vesiclepedia_1149	22807456	Homo sapiens	Quantitative proteomic analysis of exosomes from HIV-1-infected lymphocytic cells.	Lymphocytes	Protein	Differential centrifugation Ultracentrifugation	Exosomes
111	Vesiclepedia_31	10572093	Homo sapiens	Activated platelets release two types of membrane vesicles: microvesicles by surface shedding and exosomes derived from exocytosis of multivesicular bodies and alpha-granules.	Platelets	Protein	Differential centrifugation Sucrose density gradient	Exosomes
112	Vesiclepedia_802	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
113	Vesiclepedia_740	25157233	Homo sapiens	Extravillous trophoblast cells-derived exosomes promote vascular smooth muscle cell migration.	Placenta choriocarcinoma cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
114	Vesiclepedia_898	26100252	Homo sapiens	Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts	Chronic lymphocytic leukemia cells	miRNA	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
115	Vesiclepedia_78	20224111	Homo sapiens	Proteomics analysis of bladder cancer exosomes.	Urine	Protein	Differential centrifugation Sucrose density gradient	Exosomes
116	Vesiclepedia_22	15940614	Homo sapiens	Human colorectal cancer cells induce T-cell death through release of proapoptotic microvesicles: role in immune escape.	Colorectal cancer cells	Protein	Differential centrifugation	Exosomes
117	Vesiclepedia_215	21364924	Homo sapiens	Thermal- and oxidative stress causes enhanced release of NKG2D ligand-bearing immunosuppressive exosomes in leukemia/lymphoma T and B cells	B cells	Protein	Differential centrifugation Ultracentrifugation Filtration Sucrose density gradient FACS	Exosomes
118	Vesiclepedia_821	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Filtration Ultracentrifugation Sucrose and deuterium oxide density cushion	Exosomes
119	Vesiclepedia_963	25844599	Homo sapiens	Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
120	Vesiclepedia_435	22031862	Mus musculus	Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes.	Dendritic cells	miRNA	-	Exosomes/Nanovesicles
121	Vesiclepedia_1148	23173708	Rattus norvegicus	Wnt3a induces exosome secretion from primary cultured rat microglia.	Primary microglial cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
122	Vesiclepedia_1005	23463506	Homo sapiens	The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes.	T cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
123	Vesiclepedia_1045	28725021	Bos taurus	Bovine milk-derived exosomes from colostrum are enriched with proteins implicated in immune response and growth.	Bovine milk	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
124	Vesiclepedia_485	23214914	Trypanosoma cruzi	Proteomic analysis of Trypanosoma cruzi secretome: characterization of two populations of extracellular vesicles and soluble proteins.	Metacyclic trypomastigotes	Protein	-	Exosomes/Extracellular vesicles/Ectosomes
125	Vesiclepedia_1284	22345510	Rattus norvegicus	Characterization of membrane-shed microvesicles from cytokine-stimulated .-cells using proteomics strategies.	Insulinoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
126	Vesiclepedia_281	15499615	Homo sapiens	Microvesicles derived from activated platelets induce metastasis and angiogenesis in lung cancer	Lung cancer cells	mRNA	Differential centrifugation Ultracentrifugation	Exosomes
127	Vesiclepedia_923	25483805	Homo sapiens	Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties	Embryonic kidney cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
128	Vesiclepedia_325	19289371	Homo sapiens	Exosomal microRNA: a diagnostic marker for lung cancer	Plasma	miRNA	Size exclusion chromatography Immunobeads (EpCAM)	Exosomes
129	Vesiclepedia_1079	25104112	Homo sapiens	Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy.	Plasma	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Exosomes
130	Vesiclepedia_659	29982104	Mus musculus	NRP-1 targeted and cargo-loaded exosomes facilitate simultaneous imaging and therapy of glioma in vitro and in vivo.	Macrophages	Protein	Differential centrifugation Ultracentrifugation Ultrafiltration	Exosomes
131	Vesiclepedia_1069	29937354	Homo sapiens	Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors.	Glioblastoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
132	Vesiclepedia_80	20458337	Homo sapiens	MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis -Sample 2	B cells	Protein	Differential centrifugation Sucrose density gradient Immunobeads (MHC Class II)	Exosomes
133	Vesiclepedia_1278	22437826	Drosophila melanogaster	Mechanism of evenness interrupted (Evi)-exosome release at synaptic boutons.	Drosophila S2 cells	Protein	Ultracentrifugation Density gradient centrifugation	Exosomes
134	Vesiclepedia_788	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Embryonic kidney cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
135	Vesiclepedia_1219	27872147	Homo sapiens	Primary Human and Rat .-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity.	Islets	Protein	Differential centrifugation Ultracentrifugation	Exosomes
136	Vesiclepedia_71	19801663	Homo sapiens	Microenvironmental pH is a key factor for exosome traffic in tumor cells.	Melanoma cells	Protein Lipids	Differential centrifugation Sucrose density gradient	Exosomes
137	Vesiclepedia_7	12626558	Mus musculus	Mast cell-derived exosomes induce phenotypic and functional maturation of dendritic cells and elicit specific immune responses in vivo.	Mast cells	Protein	Differential centrifugation	Exosomes
138	Vesiclepedia_949	28819550	Mus musculus	Effects of storage temperature on airway exosome integrity for diagnostic and functional analyses.	Bronchoalveolar lavage fluid	Protein	Differential centrifugation Ultracentrifugation	Exosomes
139	Vesiclepedia_1267	24218614	Homo sapiens	Unexpected gain of function for the scaffolding protein plectin due to mislocalization in pancreatic cancer.	Pancreatic adenocarcinoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
140	Vesiclepedia_131	19188015	Homo sapiens	Systemic presence and tumor-growth promoting effect of ovarian carcinoma released exosomes	Ascites	Protein Lipids	Differential centrifugation Sucrose density gradient	Exosomes
141	Vesiclepedia_27	19109410	Homo sapiens	Proteomic and immunologic analyses of brain tumor exosomes.	Medulloblastoma cells	Protein	Differential centrifugation Sucrose density gradient	Exosomes
142	Vesiclepedia_1125	24347249	Homo sapiens	Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation ExoQuick	Exosomes
143	Vesiclepedia_1234	25421927	Mus musculus	Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity.	Serum	miRNA Protein	Filtration Ultracentrifugation	Exosomes
144	Vesiclepedia_534	23818640	Homo sapiens	Modulation of B-cell exosome proteins by gamma herpesvirus infection.	B cells	Protein	-	Exosomes/Microvesicles/Oncosomes/Microparticles
145	Vesiclepedia_1143	23454749	Homo sapiens	BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression.	Bone marrow mesenchymal stromal cells	Protein	Differential centrifugation Ultracentrifugation Filtration ExoQuick	Exosomes
146	Vesiclepedia_56	12147373	Homo sapiens	Malignant effusions and immunogenic tumour-derived exosomes.	Ascites	Protein	Differential centrifugation Sucrose density gradient	Exosomes
147	Vesiclepedia_62	17133577	Mus musculus	Association of citrullinated proteins with synovial exosomes.	Synovial fluid	Protein	Differential centrifugation Sucrose density gradient	Exosomes
148	Vesiclepedia_100	21828046	Rattus norvegicus	The proteo-lipidic composition of exosomes changes during reticulocyte maturation.	Reticulocytes	Protein Lipids	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
149	Vesiclepedia_1203	27780738	Homo sapiens	Next-generation sequencing-based small RNA profiling of cerebrospinal fluid exosomes.	Serum	miRNA	Differential centrifugation Ultracentrifugation	Exosomes
150	Vesiclepedia_660	29964051	Homo sapiens	Cell-free therapy based on adipose tissue stem cell-derived exosomes promotes wound healing via the PI3K/Akt signaling pathway	Adipose tissue-derived stem cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
151	Vesiclepedia_430	21595033	Homo sapiens	Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.	Urine	Protein	-	Exosomes
152	Vesiclepedia_968	25844599	Homo sapiens	Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.	Serum	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
153	Vesiclepedia_1004	23463506	Homo sapiens	The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes.	T cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
154	Vesiclepedia_60	17700640	Mus musculus	CD24 is a marker of exosomes secreted into urine and amniotic fluid.	Urine	Protein	Differential centrifugation Sucrose density gradient	Exosomes
155	Vesiclepedia_481	23161513	Homo sapiens	Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.	Colorectal cancer cells	Protein	-	Exosomes
156	Vesiclepedia_441	22251860	Homo sapiens	RNA expression patterns in serum microvesicles from patients with glioblastoma multiforme and controls.	Serum	mRNA	-	Exosomes/Microvesicles
157	Vesiclepedia_17	11907077	Homo sapiens	TCR activation of human T cells induces the production of exosomes bearing the TCR/CD3/zeta complex.	T cells	Protein	Filtration Ultracentrifugation	Exosomes
158	Vesiclepedia_87	20949044	Homo sapiens	Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line	Colorectal cancer cells	miRNA	Differential centrifugation Filtration Ultracentrifugation	Exosomes
159	Vesiclepedia_707	28811610	Homo sapiens	Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA.	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
160	Vesiclepedia_528	23767874	Homo sapiens	Biochemical and biological characterization of exosomes containing prominin-1/CD133.	Melanoma cells	Lipids	-	Exosomes/Microvesicles
161	Vesiclepedia_1197	27883272	Homo sapiens	Circulating adipocyte-derived exosomal MicroRNAs associated with decreased insulin resistance after gastric bypass.	Plasma	miRNA Metabolites	ExoQuick	Exosomes
162	Vesiclepedia_54	14975938	Homo sapiens	Proteomic analysis of exosomes isolated from human malignant pleural effusions.	Malignant pleural effusions	Protein	Differential centrifugation Sucrose density gradient	Exosomes
163	Vesiclepedia_796	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Embryonic kidney cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
164	Vesiclepedia_919	28687758	Sus scrofa	Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers	Polarised retinal pigmented epithelial cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
165	Vesiclepedia_476	23056502	Homo sapiens	Identifying mRNA, MicroRNA and Protein Profiles of Melanoma Exosomes.	Melanoma cells	miRNA	-	Exosomes
166	Vesiclepedia_829	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Filtration Ultracentrifugation Sucrose density gradient	Exosomes
167	Vesiclepedia_1156	21212511	Homo sapiens	Proteomic analysis of two types of exosomes in human whole saliva.	Saliva	Protein	Differential centrifugation Filtration Ultracentrifugation Gel filtration	Exosomes
168	Vesiclepedia_713	28811610	Homo sapiens	Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA.	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
169	Vesiclepedia_483	23214914	Trypanosoma cruzi	Proteomic analysis of Trypanosoma cruzi secretome: characterization of two populations of extracellular vesicles and soluble proteins.	Epimastigotes	Protein	-	Exosomes/Extracellular vesicles/Ectosomes
170	Vesiclepedia_928	25483805	Gallus gallus	Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties	Notochord cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
171	Vesiclepedia_1200	27780738	Homo sapiens	Next-generation sequencing-based small RNA profiling of cerebrospinal fluid exosomes.	Cerebrospinal fluid	miRNA	Differential centrifugation Ultracentrifugation	Exosomes
172	Vesiclepedia_778	29953723	Salmo salar	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Leukocytes	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
173	Vesiclepedia_995	24434149	Homo sapiens	In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome.	Ovarian cancer cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
174	Vesiclepedia_726	25471207	Homo sapiens	Intraluminal proteome and peptidome of human urinary extracellular vesicles.	Urine	Protein	Differential centrifugation Hydrostatic filtration dialysis Ultrafiltration	Exosomes
175	Vesiclepedia_809	29932869	Mus musculus	Exosomes derived from high-glucose-stimulated Schwann cells promote development of diabetic peripheral neuropathy	Schwann cells	protein	Filtration Differential centrifugation Ultracentrifugation	Exosomes
176	Vesiclepedia_123	21235781	Homo sapiens	Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages.	Plasma	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
177	Vesiclepedia_1282	22345510	Rattus norvegicus	Characterization of membrane-shed microvesicles from cytokine-stimulated .-cells using proteomics strategies.	Insulinoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
178	Vesiclepedia_69	19812188	Rattus norvegicus	Immature dendritic cell-derived exosomes rescue septic animals via milk fat globule epidermal growth factor VIII.	Dendritic cells	Protein	Differential centrifugation Sucrose density gradient	Exosomes
179	Vesiclepedia_1109	24391718	Homo sapiens	Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.	Prostate epithelial cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
180	Vesiclepedia_794	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Embryonic kidney cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
181	Vesiclepedia_109	21601258	Homo sapiens	Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage.	Malignant pleural effusions	Protein miRNA	Differential centrifugation Sucrose density gradient Immunobeads (EpCAM)	Exosomes
182	Vesiclepedia_1162	22641613	Homo sapiens	Application of systems biology principles to protein biomarker discovery: urinary exosomal proteome in renal transplantation.	Urine	Protein	Differential centrifugation Ultracentrifugation	Exosomes
183	Vesiclepedia_522	23645497	Canis lupus familiaris	Oncogenic H-Ras reprograms Madin-Darby canine kidney (MDCK) cell-derived exosomal proteins following epithelial-mesenchymal transition.	Kidney cells	Protein	-	Exosomes/Extracellular vesicles
184	Vesiclepedia_835	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Differential centrifugation Filtration ExoQuick Ultracentrifugation	Exosomes
185	Vesiclepedia_860	25776846	Homo sapiens	Human thymic epithelial primary cells produce exosomes carrying tissue-restricted antigens	Epithelial cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
186	Vesiclepedia_699	28811610	Homo sapiens	Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA.	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
187	Vesiclepedia_1027	24211404	Homo sapiens	Diabetic nephropathy induces changes in the proteome of human urinary exosomes as revealed by label-free comparative analysis.	Urine	Protein	Ultracentrifugation ExoQuick	Exosomes
188	Vesiclepedia_39	15210972	Mus musculus	Cells release prions in association with exosomes.	Mov neuroglial cell	Protein	Differential centrifugation Sucrose density gradient	Exosomes
189	Vesiclepedia_1247	25167841	Homo sapiens	Antibody-coupled monolithic silica microtips for highthroughput molecular profiling of circulating exosomes.	Serum	Protein	CD9 antibody to Mass Spectrometric Immunoassay monolith pipette tips	Exosomes
190	Vesiclepedia_1097	24513287	Mus musculus	Lipid synthesis is promoted by hypoxic adipocyte-derived exosomes in 3T3-L1 cells.	adipocytes	Protein	Differential centrifugation Ultracentrifugation Filtration	Exosomes
191	Vesiclepedia_1112	24391718	Homo sapiens	Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
192	Vesiclepedia_185	22116803	Equus caballus	Cell-Secreted Vesicles in Equine Ovarian Follicular Fluid Contain miRNAs and Proteins: A Possible New Form of Cell Communication Within the Ovarian Follicle	Follicular fluid	Protein miRNA	Differential centrifugation ExoQuick	Exosomes
193	Vesiclepedia_135	2777884	Cavia porcellus	Asymmetric Distribution of Phospholipids in the Membrane of Vesicles Released During In Vitro Maturation of Guinea Pig Reticulocytes: Evidence Precluding a Role for Aminophospholipid Translocase	Reticulocytes	Proteins Lipids	Differential centrifugation Ultracentrifugation	Exosomes
194	Vesiclepedia_999	24355714	Homo sapiens	Proteomic analysis and immune properties of exosomes released by macrophages infected with Mycobacterium avium.	Leukemia cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
195	Vesiclepedia_43	17076679	Homo sapiens	Specific isolation of placenta-derived exosomes from the circulation of pregnant women and their immunoregulatory consequences.	Plasma	Protein	Size exclusion chromatography Ultracentrifugation Immunobeads (CD3, CD19, CD56, CD83, PLAP)	Exosomes
196	Vesiclepedia_752	29963269	Homo sapiens	Mining of potential microRNAs with clinical correlation - regulation of syndecan-1 expression by miR-122-5p altered mobility of breast cancer cells and possible correlation with liver injury	Hepatoma cells	Protein	Total Exosome Isolation Kit Differential centrifugation	Exosomes
197	Vesiclepedia_947	28819550	Mus musculus	Effects of storage temperature on airway exosome integrity for diagnostic and functional analyses.	Bronchoalveolar lavage fluid	Protein	Differential centrifugation Ultracentrifugation	Exosomes
198	Vesiclepedia_974	22808001	Homo sapiens	Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment.	Serum	Protein	Filtration ExoQuick	Exosomes
199	Vesiclepedia_129	14965343	Rattus norvegicus	Mast cell- and dendritic cell-derived exosomes display a specific lipid composition and an unusual membrane organization	Tumoral mast cells	Lipids	Differential centrifugation Ultracentrifugation	Exosomes
200	Vesiclepedia_91	21252909	Homo sapiens	Diacylglycerol kinase a regulates the formation and polarisation of mature multivesicular bodies involved in the secretion of Fas ligand-containing exosomes in T lymphocytes	T cells	Protein Lipids	Differential centrifugation Ultracentrifugation	Exosomes
201	Vesiclepedia_36	19367702	Mus musculus	Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.	Hepatocytes	Protein	Differential centrifugation Filtration	Exosomes
202	Vesiclepedia_877	29955024	Homo sapiens	Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells	Embryonic kidney cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
203	Vesiclepedia_656	28753793	Homo sapiens	MicroRNAs in Serum Exosomes as Potential Biomarkers in Clear-cell Renal Cell Carcinoma.	Serum	miRNA	Total Exosome Isolation Kit Differential centrifugation Ultracentrifugation Immunobeads (EpCAM)	Exosomes
204	Vesiclepedia_1258	24400796	Homo sapiens	Exosomal proteins in the aqueous humor as novel biomarkers in patients with neovascular age-related macular degeneration.	Aqueous humor	Protein	ExoQuick	Exosomes
205	Vesiclepedia_141	22723089	Homo sapiens	Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes.	Prostate cancer cells	Protein	Sucrose density gradient	Exosomes
206	Vesiclepedia_966	25844599	Homo sapiens	Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.	Serum	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
207	Vesiclepedia_353	24115447	Homo sapiens	Comparative proteomics evaluation of plasma exosome isolation techniques and assessment of the stability of exosomes in normal human blood plasma	Plasma	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
208	Vesiclepedia_808	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
209	Vesiclepedia_1092	25065644	Homo sapiens	Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells.	Duodenal cancer cells	Protein	Differential centrifugation Filtration Ultrafiltration	Exosomes
210	Vesiclepedia_1071	29937354	Homo sapiens	Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors.	Glioblastoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
211	Vesiclepedia_1155	21212511	Homo sapiens	Proteomic analysis of two types of exosomes in human whole saliva.	Saliva	Protein	Differential centrifugation Filtration Ultracentrifugation Gel filtration	Exosomes
212	Vesiclepedia_792	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Embryonic kidney cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
213	Vesiclepedia_10	11390481	Mus musculus	Proteomic analysis of dendritic cell-derived exosomes: a secreted subcellular compartment distinct from apoptotic vesicles.	Dendritic cells	Protein	Differential centrifugation Sucrose density gradient	Exosomes
214	Vesiclepedia_1269	24218614	Homo sapiens	Unexpected gain of function for the scaffolding protein plectin due to mislocalization in pancreatic cancer.	Pancreatic adenocarcinoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
215	Vesiclepedia_772	29953723	Salmo salar	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Leukocytes	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
216	Vesiclepedia_458	22740476	Homo sapiens	Restoration of full-length APC protein in SW480 colon cancer cells induces exosome-mediated secretion of DKK-4.	Colorectal cancer cells	Protein	-	Exosomes
217	Vesiclepedia_68	19619303	Homo sapiens	Claudin-containing exosomes in the peripheral circulation of women with ovarian cancer.	Plasma	Protein	Differential centrifugation	Exosomes
218	Vesiclepedia_967	25844599	Homo sapiens	Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.	Serum	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
219	Vesiclepedia_190	22116803	Equus caballus	Cell-Secreted Vesicles in Equine Ovarian Follicular Fluid Contain miRNAs and Proteins: A Possible New Form of Cell Communication Within the Ovarian Follicle	Follicular fluid	miRNA	Differential centrifugation ExoQuick	Exosomes
220	Vesiclepedia_102	21082674	Homo sapiens	Comprehensive analysis of low-abundance proteins in human urinary exosomes using peptide ligand library technology, peptide OFFGEL fractionation and nanoHPLC-chip-MS/MS.	Urine	Protein	Differential centrifugation Ultracentrifugation	Exosomes
221	Vesiclepedia_661	29956871	Homo sapiens	Expression analysis of extracellular microRNA in bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis	Bronchoalveolar lavage fluid	Protein	Differential centrifugation Ultracentrifugation Filtration	Exosomes
222	Vesiclepedia_1054	29115712	Mus musculus	Proteomic Profiling of Exosomes Secreted by Breast Cancer Cells with Varying Metastatic Potential.	Breast cancer cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
223	Vesiclepedia_769	29953723	Salmo salar	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Leukocytes	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
224	Vesiclepedia_111	21601258	Homo sapiens	Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage.	Serum	Protein miRNA	Differential centrifugation Sucrose density gradient Immunobeads (CD24)	Exosomes
225	Vesiclepedia_987	25261472	Homo sapiens	Complex N-linked glycans serve as a determinant for exosome/microvesicle cargo recruitment.	Melanoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes/Microvesicles
226	Vesiclepedia_1091	25065644	Homo sapiens	Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells.	Duodenal cancer cells	Protein	Differential centrifugation Filtration Ultrafiltration	Exosomes
227	Vesiclepedia_76	20224111	Homo sapiens	Proteomics analysis of bladder cancer exosomes.	Bladder cancer cells	Protein	Differential centrifugation Sucrose density gradient	Exosomes
228	Vesiclepedia_830	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Filtration Ultracentrifugation Sucrose density gradient	Exosomes
229	Vesiclepedia_1100	24513287	Mus musculus	Lipid synthesis is promoted by hypoxic adipocyte-derived exosomes in 3T3-L1 cells.	adipocytes	Protein	Differential centrifugation Ultracentrifugation Filtration	Exosomes
230	Vesiclepedia_1134	23861904	Homo sapiens	Exosomal signaling during hypoxia mediates microvascular endothelial cell migration and vasculogenesis.	Placental mesenchymal stem cells	Protein	Differential centrifugation Ultracentrifugation Ultrafiltration Density gradient centrifugation	Exosomes
231	Vesiclepedia_144	22723089	Homo sapiens	Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes.	Prostate cancer cells	Protein	Sucrose density gradient	Exosomes
232	Vesiclepedia_755	29963269	Homo sapiens	Mining of potential microRNAs with clinical correlation - regulation of syndecan-1 expression by miR-122-5p altered mobility of breast cancer cells and possible correlation with liver injury	Hepatoma cells	miRNA	Total Exosome Isolation Kit Differential centrifugation	Exosomes
233	Vesiclepedia_114	21557262	Homo sapiens	Proteomic identification of exosomal LRG1: A potential urinary biomarker for detecting NSCLC.	Urine	Protein	Differential centrifugation Ultracentrifugation	Exosomes
234	Vesiclepedia_189	21741384	Homo sapiens	A filtration-based protocol to isolate human plasma membrane-derived vesicles and exosomes from blood plasma	Plasma	Protein	Differential centrifugation Filtration	Exosomes
235	Vesiclepedia_346	22965126	Mus musculus	Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells.	Neuronal cells	Protein miRNA	Differential centrifugation Filtration Ultracentrifugation	Exosomes
236	Vesiclepedia_1095	24976626	Homo sapiens	Exosomal transfer from human renal proximal tubule cells to distal tubule and collecting duct cells.	Renal proximal tubule cells	Protein	Differential centrifugation Ultracentrifugation Immunoaffinity	Exosomes
237	Vesiclepedia_524	23658846	Mus musculus	Immunomodulatory impact of leishmania-induced macrophage exosomes: a comparative proteomic and functional analysis.	Macrophages	Protein	-	Exosomes
238	Vesiclepedia_1085	25104112	Homo sapiens	Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy.	Plasma	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Exosomes
239	Vesiclepedia_99	21828046	Rattus norvegicus	The proteo-lipidic composition of exosomes changes during reticulocyte maturation.	Reticulocytes	Protein Lipids	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
240	Vesiclepedia_771	29953723	Salmo salar	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Leukocytes	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
241	Vesiclepedia_994	24434149	Homo sapiens	In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome.	Ovarian cancer cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
242	Vesiclepedia_333	20976003	Homo sapiens	Selective release of microRNA species from normal and malignant mammary epithelial cells	Breast cancer cells	Protein miRNA	Differential centrifugation Filtration	Exosomes
243	Vesiclepedia_655	28290293	Bos taurus	Comparative proteomic analysis of milk-derived exosomes in human and bovine colostrum and mature milk samples by iTRAQ-coupled LC-MS/MS.	Bovine milk	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Exosomes
244	Vesiclepedia_112	21601258	Homo sapiens	Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage.	Serum	Protein miRNA	Differential centrifugation Sucrose density gradient	Exosomes
245	Vesiclepedia_810	29932869	Mus musculus	Exosomes derived from high-glucose-stimulated Schwann cells promote development of diabetic peripheral neuropathy	Schwann cells	miRNA	Filtration Differential centrifugation Ultracentrifugation	Exosomes
246	Vesiclepedia_336	20976003	Homo sapiens	Selective release of microRNA species from normal and malignant mammary epithelial cells	Breast cancer cells	Protein miRNA	Differential centrifugation Filtration	Exosomes
247	Vesiclepedia_88	20949044	Homo sapiens	Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line	Stomach cancer cells	Protein miRNA	Differential centrifugation Filtration Ultracentrifugation	Exosomes
248	Vesiclepedia_674	29953960	Homo sapiens	Exosomes derived from calcium oxalate-exposed macrophages enhance IL-8 production from renal cells, neutrophil migration and crystal invasion through extracellular matrix.	Macrophages	Protein	Microfiltration Differential centrifugation Ultracentrifugation	Exosomes
249	Vesiclepedia_37	10878338	Homo sapiens	Direct immunosuppressive effects of EBV-encoded latent membrane protein 1.	B cells	Protein	Differential centrifugation	Exosomes
250	Vesiclepedia_518	23585443	Homo sapiens	Proteome profiling of exosomes derived from human primary and metastatic colorectal cells reveal differential expression of key metastatic factors and signal transduction components.	Colorectal cancer cells	Protein	-	Exosomes/Membrane vesicles
251	Vesiclepedia_58	17700640	Homo sapiens	CD24 is a marker of exosomes secreted into urine and amniotic fluid.	Amniotic fluid	Protein	Differential centrifugation Sucrose density gradient	Exosomes
252	Vesiclepedia_11	12519789	Homo sapiens	Proteomic and biochemical analyses of human B cell-derived exosomes. Potential implications for their function and multivesicular body formation.	B cells	Protein Lipids	Differential centrifugation Sucrose density gradient	Exosomes
253	Vesiclepedia_864	22046311	Mus musculus	Exosomes from Plasmodium yoelii-infected reticulocytes protect mice from lethal infections	Plasma	Protein	Differential centrifugation Filtration Sucrose density gradient Ultracentrifugation	Exosomes
254	Vesiclepedia_42	15908444	Homo sapiens	Exosomal-like vesicles are present in human blood plasma.	Bone marrow cells	Protein	Differential centrifugation Filtration Sucrose density gradient	Exosomes
255	Vesiclepedia_118	21362503	Homo sapiens	Protein profile of exosomes from trabecular meshwork cells.	Tabecular meshwork cells	Protein	Differential centrifugation Sucrose density gradient	Exosomes
256	Vesiclepedia_117	21505438	Homo sapiens	Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells.	Dendritic cells	Protein miRNA	Differential centrifugation Filtration Ultracentrifugation	Exosomes
257	Vesiclepedia_411	20124223	Homo sapiens	Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.	Squamous carcinoma cells	Protein	-	Exosomes
258	Vesiclepedia_884	29955024	Homo sapiens	Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells	Myeloid leukemia cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
259	Vesiclepedia_431	21595033	Homo sapiens	Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.	Urine	Protein	-	Exosomes
260	Vesiclepedia_538	23844026	Homo sapiens	Characterization of human thymic exosomes.	Thymus	Protein	-	Exosomes
261	Vesiclepedia_107	21763319	Homo sapiens	Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells.	Pancreatic adenocarcinoma cells	Protein	Differential centrifugation Filtration Ultrafiltration Ultracentrifugation	Exosomes
262	Vesiclepedia_825	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Filtration Ultracentrifugation Sucrose density gradient	Exosomes
263	Vesiclepedia_673	29953960	Homo sapiens	Exosomes derived from calcium oxalate-exposed macrophages enhance IL-8 production from renal cells, neutrophil migration and crystal invasion through extracellular matrix.	Macrophages	Protein	Microfiltration Differential centrifugation Ultracentrifugation	Exosomes
264	Vesiclepedia_199	21609964	Homo sapiens	Characterization of extracellular circulating microRNA	Plasma	Protein	Differential centrifugation Filtration	Exosomes
265	Vesiclepedia_886	25102470	Homo sapiens	Examination of the specificity of tumor cell derived exosomes with tumor cells in vitro	Breast cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
266	Vesiclepedia_554	24009898	Mus musculus	Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.	Cardiomyocytes	mRNA	-	Exosomes/Extracellular vesicles
267	Vesiclepedia_65	19415654	Homo sapiens	Proteomics of MUC1-containing lipid rafts from plasma membranes and exosomes of human breast carcinoma cells MCF-7.	Breast cancer cells	Protein	Differential centrifugation Sucrose density gradient	Exosomes
268	Vesiclepedia_876	29955024	Homo sapiens	Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells	Embryonic kidney cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
269	Vesiclepedia_1216	27872147	Rattus norvegicus	Primary Human and Rat .-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity.	Islets	Protein	Differential centrifugation Ultracentrifugation	Exosomes
270	Vesiclepedia_444	22418980	Homo sapiens	A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.	Urine	Protein	-	Exosomes
271	Vesiclepedia_669	29953960	Homo sapiens	Exosomes derived from calcium oxalate-exposed macrophages enhance IL-8 production from renal cells, neutrophil migration and crystal invasion through extracellular matrix.	Macrophages	Protein	Microfiltration Differential centrifugation Ultracentrifugation	Exosomes
272	Vesiclepedia_6	11306949	Mus musculus	Nonspecific B and T cell-stimulatory activity mediated by mast cells is associated with exosomes.	Mast cells	Protein	-	Exosomes
273	Vesiclepedia_389	18819103	Homo sapiens	Structural heterogeneity and protein composition of exosome-like vesicles (prostasomes) in human semen.	Seminal fluid	Protein	-	Exosomes/Prostasomes
274	Vesiclepedia_863	22046311	Mus musculus	Exosomes from Plasmodium yoelii-infected reticulocytes protect mice from lethal infections	Plasma	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
275	Vesiclepedia_64	18520029	Homo sapiens	Exosome-like vesicles with dipeptidyl peptidase IV in human saliva.	Saliva	Protein	Filtration Diafiltration Gel filtration	Exosomes
276	Vesiclepedia_670	29953960	Homo sapiens	Exosomes derived from calcium oxalate-exposed macrophages enhance IL-8 production from renal cells, neutrophil migration and crystal invasion through extracellular matrix.	Macrophages	Protein	Microfiltration Differential centrifugation Ultracentrifugation	Exosomes
277	Vesiclepedia_901	26100252	Homo sapiens	Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts	Chronic lymphocytic leukemia cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
278	Vesiclepedia_827	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Filtration Ultracentrifugation Sucrose density gradient	Exosomes
279	Vesiclepedia_30	16446100	Rattus norvegicus	Exosomes are released by cultured cortical neurones.	Cortical neurones	Protein	Differential centrifugation Sucrose density gradient	Exosomes
280	Vesiclepedia_976	22808001	Homo sapiens	Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment.	Serum	Protein	Filtration ExoQuick	Exosomes
281	Vesiclepedia_115	21505438	Homo sapiens	Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells.	T cells	Protein miRNA	Differential centrifugation Filtration Ultracentrifugation	Exosomes
282	Vesiclepedia_765	29953723	Salmo salar	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Leukocytes	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
283	Vesiclepedia_1201	27780738	Homo sapiens	Next-generation sequencing-based small RNA profiling of cerebrospinal fluid exosomes.	Cerebrospinal fluid	miRNA	Differential centrifugation Ultracentrifugation	Exosomes
284	Vesiclepedia_1133	23861904	Homo sapiens	Exosomal signaling during hypoxia mediates microvascular endothelial cell migration and vasculogenesis.	Placental mesenchymal stem cells	Protein	Differential centrifugation Ultracentrifugation Ultrafiltration Density gradient centrifugation	Exosomes
285	Vesiclepedia_44	19028452	Homo sapiens	Proteomic profiling of human plasma exosomes identifies PPARgamma as an exosome-associated protein.	Plasma	Protein	Filtration Size exclusion chromatography Sucrose density gradient	Exosomes
286	Vesiclepedia_104	21763319	Homo sapiens	Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells.	Pancreatic adenocarcinoma cells	Protein	Differential centrifugation Filtration Ultrafiltration Ultracentrifugation	Exosomes
287	Vesiclepedia_545	23983189	Homo sapiens	Characterization of Multiple Myeloma Vesicles by Label-Free Relative Quantitation.	B cells	Protein	-	Exosomes/Extracellular vesicles/Microvesicles
288	Vesiclepedia_357	24352158	Homo sapiens	Characterization and deep sequencing analysis of exosomal miRNA in human urine	Urine	miRNA	Differential centrifugation Norgen Biotek Exosome kit	Exosomes
289	Vesiclepedia_340	20615901	Homo sapiens	Export of microRNAs and microRNA-protective protein by mammalian cells	Lung cancer cells	miRNA	Differential centrifugation	Exosomes
290	Vesiclepedia_1262	24371517	Homo sapiens	Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients.	Urine	Protein	Differential centrifugation Ultracentrifugation	Exosomes
291	Vesiclepedia_38	15210972	Oryctolagus cuniculus	Cells release prions in association with exosomes.	Epithelial cells	Protein	Differential centrifugation Sucrose density gradient	Exosomes
292	Vesiclepedia_1114	24391718	Homo sapiens	Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
293	Vesiclepedia_910	28687758	Sus scrofa	Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers	Polarised retinal pigmented epithelial cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
294	Vesiclepedia_777	29953723	Salmo salar	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Leukocytes	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
295	Vesiclepedia_513	23533145	Homo sapiens	In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.	Urine	Protein	-	Exosomes/Microvesicles
296	Vesiclepedia_134	15304316	Rattus norvegicus	PLD2 is enriched on exosomes and its activity is correlated to the release of exosomes	Basophilic leukemia cells	Protein Lipids	Differential centrifugation	Exosomes
297	Vesiclepedia_187	22116803	Equus caballus	Cell-Secreted Vesicles in Equine Ovarian Follicular Fluid Contain miRNAs and Proteins: A Possible New Form of Cell Communication Within the Ovarian Follicle	Serum	Protein	Differential centrifugation ExoQuick	Exosomes
298	Vesiclepedia_1083	25104112	Homo sapiens	Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy.	Plasma	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Exosomes
299	Vesiclepedia_791	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Embryonic kidney cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
300	Vesiclepedia_34	19190083	Homo sapiens	Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense.	Tracheobronchial cells	Protein mRNA	Differential centrifugation Filtration Sucrose density gradient	Exosomes
301	Vesiclepedia_85	20949044	Homo sapiens	Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line	Lung cancer cells	miRNA	Differential centrifugation Filtration Ultracentrifugation	Exosomes
302	Vesiclepedia_1126	24295599	Mus musculus	Exosomes from myeloid-derived suppressor cells carry biologically active proteins.	Myeloid-derived suppressor cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
303	Vesiclepedia_355	24115447	Homo sapiens	Comparative proteomics evaluation of plasma exosome isolation techniques and assessment of the stability of exosomes in normal human blood plasma	Plasma	Protein	Differential centrifugation Filtration Ultracentrifugation Immunoaffinity (EpCAM)	Exosomes
304	Vesiclepedia_540	23886663	Homo sapiens	LRRK2 Secretion in Exosomes is Regulated by 14-3-3.	Urine	Protein	-	Exosomes/Microvesicles
305	Vesiclepedia_334	20976003	Homo sapiens	Selective release of microRNA species from normal and malignant mammary epithelial cells	Breast cancer cells	Protein miRNA	Differential centrifugation Filtration	Exosomes
306	Vesiclepedia_1202	27780738	Homo sapiens	Next-generation sequencing-based small RNA profiling of cerebrospinal fluid exosomes.	Cerebrospinal fluid	miRNA	Differential centrifugation Ultracentrifugation	Exosomes
307	Vesiclepedia_820	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Differential centrifugation Filtration ExoQuick Ultracentrifugation	Exosomes
308	Vesiclepedia_66	19199708	Homo sapiens	Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).	Saliva	Protein	Differential centrifugation	Exosomes
309	Vesiclepedia_374	18039940	Cryptococcus neoformans	Extracellular vesicles produced by Cryptococcus neoformans contain protein components associated with virulence.	Cryptococcus neoformans	Protein	-	Exosomes/Extracellular vesicles
310	Vesiclepedia_1142	23454749	Homo sapiens	BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression.	Bone marrow mesenchymal stromal cells	Protein	Differential centrifugation Ultracentrifugation Filtration ExoQuick	Exosomes
311	Vesiclepedia_489	23260141	Mus musculus	Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.	Fibroblasts	Protein	-	Exosomes
312	Vesiclepedia_1098	24513287	Mus musculus	Lipid synthesis is promoted by hypoxic adipocyte-derived exosomes in 3T3-L1 cells.	adipocytes	Protein	Differential centrifugation Ultracentrifugation Filtration	Exosomes
313	Vesiclepedia_958	26196085	Homo sapiens	Identification of prostate cancer biomarkers in urinary exosomes.	Urine	Protein	Differential centrifugation Ultracentrifugation Filtration	Exosomes
314	Vesiclepedia_525	23658846	Mus musculus	Immunomodulatory impact of leishmania-induced macrophage exosomes: a comparative proteomic and functional analysis.	Macrophages	Protein	-	Exosomes
315	Vesiclepedia_688	28170197	Homo sapiens	Enhanced Cardioprotection by Human Endometrium Mesenchymal Stem Cells Driven by Exosomal MicroRNA-21	Endometrium-derived mesenchymal stem cells	miRNA	Differential centrifugation Filtration Ultracentrifugation	Exosomes
316	Vesiclepedia_75	19381331	Homo sapiens	High levels of exosomes expressing CD63 and caveolin-1 in plasma of melanoma patients.	Plasma	Protein	Differential centrifugation	Exosomes
317	Vesiclepedia_498	23376485	Homo sapiens	Proteomic analysis of podocyte exosome-enriched fraction from normal human urine.	Urine	Protein	-	Exosomes/Membrane vesicles
318	Vesiclepedia_330	20304794	Homo sapiens	Functional delivery of viral miRNAs via exosomes	B cells	miRNA	Differential centrifugation	Exosomes
319	Vesiclepedia_819	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Differential centrifugation Filtration ExoQuick Ultracentrifugation	Exosomes
320	Vesiclepedia_424	21179422	Mus musculus	Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.	Mast cells	mRNA	-	Exosomes/Nanovesicles
321	Vesiclepedia_536	23818640	Homo sapiens	Modulation of B-cell exosome proteins by gamma herpesvirus infection.	B cells	Protein	-	Exosomes/Microvesicles/Oncosomes/Microparticles
322	Vesiclepedia_836	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Differential centrifugation Filtration ExoQuick Ultracentrifugation	Exosomes
323	Vesiclepedia_440	22251860	Homo sapiens	RNA expression patterns in serum microvesicles from patients with glioblastoma multiforme and controls.	Serum	mRNA	-	Exosomes/Microvesicles
324	Vesiclepedia_1264	24371517	Homo sapiens	Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients.	Urine	Protein	Differential centrifugation Ultracentrifugation	Exosomes
325	Vesiclepedia_899	26100252	Homo sapiens	Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts	Chronic lymphocytic leukemia cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
326	Vesiclepedia_32	18452139	Homo sapiens	Primary human keratinocytes externalize stratifin protein via exosomes.	Keratinocytes	Protein	Differential centrifugation Sucrose density gradient Diafiltration	Exosomes
327	Vesiclepedia_828	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Filtration Ultracentrifugation Sucrose density gradient	Exosomes
328	Vesiclepedia_119	21362503	Homo sapiens	Protein profile of exosomes from trabecular meshwork cells.	Urine	Protein	Differential centrifugation Sucrose density gradient	Exosomes
329	Vesiclepedia_52	14975938	Homo sapiens	Proteomic analysis of exosomes isolated from human malignant pleural effusions.	Malignant pleural effusions	Protein	Differential centrifugation Sucrose density gradient	Exosomes
330	Vesiclepedia_1136	23861904	Homo sapiens	Exosomal signaling during hypoxia mediates microvascular endothelial cell migration and vasculogenesis.	Placental mesenchymal stem cells	Protein	Differential centrifugation Ultracentrifugation Ultrafiltration Density gradient centrifugation	Exosomes
331	Vesiclepedia_1076	25104112	Homo sapiens	Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy.	Plasma	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Exosomes
332	Vesiclepedia_1073	25104112	Homo sapiens	Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy.	Plasma	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Exosomes
333	Vesiclepedia_929	25483805	Gallus gallus	Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties	Notochord cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
334	Vesiclepedia_89	20424270	Rattus norvegicus	Exosomes account for vesicle-mediated transcellular transport of activatable phospholipases and prostaglandins.	Basophilic leukemia cells	Protein Lipids	Differential centrifugation Sucrose density gradient	Exosomes
335	Vesiclepedia_116	21505438	Homo sapiens	Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells.	B cells	Protein miRNA	Differential centrifugation Filtration Ultracentrifugation	Exosomes
336	Vesiclepedia_21	19837982	Homo sapiens	Proteomic and bioinformatic analysis of immunoaffinity-purified exosomes derived from the human colon tumor cell line LIM1215.	Colorectal cancer cells	Protein	Filtration Ultracentrifugation Sucrose density gradient	Exosomes
337	Vesiclepedia_113	21557262	Homo sapiens	Proteomic identification of exosomal LRG1: A potential urinary biomarker for detecting NSCLC.	Urine	Protein	Differential centrifugation Ultracentrifugation	Exosomes
338	Vesiclepedia_1074	25104112	Homo sapiens	Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy.	Plasma	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Exosomes
339	Vesiclepedia_801	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Embryonic kidney cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
340	Vesiclepedia_805	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
341	Vesiclepedia_509	23521563	Homo sapiens	First identification of Ewing's sarcoma-derived extracellular vesicles and exploration of their biological and potential diagnostic implications.	Ewing's sarcoma cells	mRNA	-	Exosomes/Extracellular vesicles
342	Vesiclepedia_480	23161513	Homo sapiens	Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.	Colorectal cancer cells	Protein	-	Exosomes
343	Vesiclepedia_1137	23861904	Homo sapiens	Exosomal signaling during hypoxia mediates microvascular endothelial cell migration and vasculogenesis.	Placental mesenchymal stem cells	Protein	Differential centrifugation Ultracentrifugation Ultrafiltration Density gradient centrifugation	Exosomes
344	Vesiclepedia_993	24434149	Homo sapiens	In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome.	Ovarian cancer cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
345	Vesiclepedia_429	21595033	Homo sapiens	Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.	Urine	Protein	-	Exosomes
346	Vesiclepedia_28	19109410	Homo sapiens	Proteomic and immunologic analyses of brain tumor exosomes.	Glioma cells	Protein	Differential centrifugation Sucrose density gradient	Exosomes
347	Vesiclepedia_1140	23454749	Homo sapiens	BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression.	Bone marrow mesenchymal stromal cells	Protein	Differential centrifugation Ultracentrifugation Filtration ExoQuick	Exosomes
348	Vesiclepedia_450	22451062	Homo sapiens	A hyphenated microLC-Q-TOF-MS platform for exosomal lipidomics investigations: application to RCC urinary exosomes.	Urine	Lipids	-	Exosomes
349	Vesiclepedia_1144	23454749	Homo sapiens	BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression.	Bone marrow mesenchymal stromal cells	Protein	Differential centrifugation Ultracentrifugation Filtration ExoQuick	Exosomes
350	Vesiclepedia_658	28753793	Homo sapiens	MicroRNAs in Serum Exosomes as Potential Biomarkers in Clear-cell Renal Cell Carcinoma.	Serum	miRNA	Total Exosome Isolation Kit Differential centrifugation Ultracentrifugation Immunobeads (EpCAM)	Exosomes
351	Vesiclepedia_143	22723089	Homo sapiens	Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes.	Prostate cancer cells	Protein	Sucrose density gradient	Exosomes
352	Vesiclepedia_786	29953723	Oncorhynchus tshawytscha	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Embryonic cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
353	Vesiclepedia_1022	19665478	Salmo salar	CpG-induced secretion of MHCIIbeta and exosomes from salmon (Salmo salar) APCs.	Head kidney leukocytes	Protein	Differential centrifugation Ultracentrifugation	Exosomes
354	Vesiclepedia_342	22965126	Mus musculus	Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells.	Neuronal cells	miRNA	Differential centrifugation Filtration Ultracentrifugation	Exosomes
355	Vesiclepedia_35	19367702	Rattus norvegicus	Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.	Hepatocytes	Protein	Differential centrifugation Filtration Sucrose density gradient	Exosomes
356	Vesiclepedia_451	22451062	Homo sapiens	A hyphenated microLC-Q-TOF-MS platform for exosomal lipidomics investigations: application to RCC urinary exosomes.	Urine	Lipids	-	Exosomes
357	Vesiclepedia_761	29953723	Salmo salar	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Leukocytes	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
358	Vesiclepedia_977	22808001	Homo sapiens	Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment.	Serum	Protein	Filtration ExoQuick	Exosomes
359	Vesiclepedia_823	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Filtration Ultracentrifugation Sucrose density gradient	Exosomes
360	Vesiclepedia_73	18494037	Mus musculus	Difference gel electrophoresis analysis of Ras-transformed fibroblast cell-derived exosomes.	Embryonic fibroblasts	Protein	Differential centrifugation	Exosomes
361	Vesiclepedia_964	25844599	Homo sapiens	Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
362	Vesiclepedia_132	19188015	Homo sapiens	Systemic presence and tumor-growth promoting effect of ovarian carcinoma released exosomes	Ovarian cancer cells	Protein Lipids	Differential centrifugation Sucrose density gradient	Exosomes
363	Vesiclepedia_136	22723089	Homo sapiens	Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes.	Prostate cancer cells	Protein	Sucrose density gradient	Exosomes
364	Vesiclepedia_1242	25261722	Homo sapiens	Inflammatory cytokines, interleukin-1 beta and tumor necrosis factor-alpha, upregulated in glioblastoma multiforme, raise the levels of CRYAB in exosomes secreted by U373 glioma cells.	Glioblastoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
365	Vesiclepedia_815	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Differential centrifugation Filtration ExoQuick Ultracentrifugation	Exosomes
366	Vesiclepedia_475	23056502	Homo sapiens	Identifying mRNA, MicroRNA and Protein Profiles of Melanoma Exosomes.	Melanoma cells	mRNA	-	Exosomes
367	Vesiclepedia_146	22723089	Homo sapiens	Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes.	Prostate cancer cells	Protein	Sucrose density gradient	Exosomes
368	Vesiclepedia_457	22723089	Homo sapiens	Exosomes as Biomarker Enriched Microvesicles: Characterization of Exosomal Proteins derived from a Panel of Prostate Cell Lines with distinct AR phenotypes.	Prostate cancer cells	Lipids	-	Exosomes/Membrane vesicles/Microvesicles
369	Vesiclepedia_51	14975938	Homo sapiens	Proteomic analysis of exosomes isolated from human malignant pleural effusions.	Malignant pleural effusions	Protein	Differential centrifugation Sucrose density gradient	Exosomes
370	Vesiclepedia_12	15478216	Homo sapiens	Proteomic analysis of melanoma-derived exosomes by two-dimensional polyacrylamide gel electrophoresis and mass spectrometry.	Melanoma cells	Protein	Filtration Ultracentrifugation Sucrose density gradient	Exosomes
371	Vesiclepedia_1252	24939845	Homo sapiens	Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein.	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
372	Vesiclepedia_391	19327352	Bos taurus	Anchorage-independent growth of breast carcinoma cells is mediated by serum exosomes.	Serum	Protein	-	Exosomes
373	Vesiclepedia_865	22046311	Mus musculus	Exosomes from Plasmodium yoelii-infected reticulocytes protect mice from lethal infections	Reticulocytes	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
374	Vesiclepedia_1104	24391718	Homo sapiens	Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.	Prostate epithelial cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
375	Vesiclepedia_33	21136642	Mus musculus	Oligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons?	Oligodendrocytes	Protein	Differential centrifugation Sucrose density gradient	Exosomes
376	Vesiclepedia_691	28170197	Homo sapiens	Enhanced Cardioprotection by Human Endometrium Mesenchymal Stem Cells Driven by Exosomal MicroRNA-21	Endometrium-derived mesenchymal stem cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
377	Vesiclepedia_327	20428099	Homo sapiens	Nucleic acids within urinary exosomes/microvesicles are potential biomarkers for renal disease	Urine	mRNA	Differential centrifugation Ultracentrifugation	Exosomes
378	Vesiclepedia_452	22506041	Mus musculus	Cardiomyocyte microvesicles contain DNA/RNA and convey biological messages to target cells.	Cardiomyocytes	mRNA	-	Exosomes/Membrane vesicles/Microvesicles/Prostasomes
379	Vesiclepedia_1248	24939845	Homo sapiens	Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein.	Leukemia cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
380	Vesiclepedia_784	29953723	Salmo salar	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Leukocytes	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
381	Vesiclepedia_95	21828046	Rattus norvegicus	The proteo-lipidic composition of exosomes changes during reticulocyte maturation.	Reticulocytes	Protein Lipids	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
382	Vesiclepedia_692	28170197	Homo sapiens	Enhanced Cardioprotection by Human Endometrium Mesenchymal Stem Cells Driven by Exosomal MicroRNA-21	Adipose-derived mesenchymal stem cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
383	Vesiclepedia_764	29953723	Salmo salar	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Leukocytes	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
384	Vesiclepedia_1249	24939845	Homo sapiens	Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein.	Leukemia cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
385	Vesiclepedia_1106	24391718	Homo sapiens	Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.	Prostate epithelial cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
386	Vesiclepedia_814	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Differential centrifugation Filtration ExoQuick Ultracentrifugation	Exosomes
387	Vesiclepedia_1096	24976626	Homo sapiens	Exosomal transfer from human renal proximal tubule cells to distal tubule and collecting duct cells.	Renal proximal tubule cells	Protein	Differential centrifugation Ultracentrifugation Immunoaffinity	Exosomes
388	Vesiclepedia_722	25802036	Homo sapiens	Glioblastoma-derived extracellular vesicles modify the phenotype of monocytic cells.	Glioblastoma cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
389	Vesiclepedia_760	29953723	Salmo salar	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Leukocytes	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
390	Vesiclepedia_70	19812188	Rattus norvegicus	Immature dendritic cell-derived exosomes rescue septic animals via milk fat globule epidermal growth factor VIII.	Dendritic cells	Protein	Differential centrifugation	Exosomes
391	Vesiclepedia_1257	24400796	Homo sapiens	Exosomal proteins in the aqueous humor as novel biomarkers in patients with neovascular age-related macular degeneration.	Retinal pigment epithelial cells	Protein	ExoQuick	Exosomes
392	Vesiclepedia_419	21136642	Mus musculus	Oligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons?	Oligodendrocytes	Protein	-	Exosomes
393	Vesiclepedia_1094	25065644	Homo sapiens	Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells.	Duodenal cancer cells	Protein	Differential centrifugation Filtration Ultrafiltration	Exosomes
394	Vesiclepedia_783	29953723	Salmo salar	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Leukocytes	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
395	Vesiclepedia_718	26148937	Homo sapiens	Proteomics profiling of cholangiocarcinoma exosomes: A potential role of oncogenic protein transferring in cancer progression.	Cholangiocarcinoma cells	Protein	Differential centrifugation Ultracentrifugation Filtration	Exosomes
396	Vesiclepedia_1006	23463506	Mus musculus	The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes.	T cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
397	Vesiclepedia_1122	24347249	Homo sapiens	Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation ExoQuick	Exosomes
398	Vesiclepedia_1286	20880880	Homo sapiens	Proinflammatory exosomes in bronchoalveolar lavage fluid of patients with sarcoidosis.	Bronchoalveolar lavage fluid	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
399	Vesiclepedia_959	26196085	Homo sapiens	Identification of prostate cancer biomarkers in urinary exosomes.	Urine	Protein	Differential centrifugation Ultracentrifugation Filtration	Exosomes
400	Vesiclepedia_128	14965343	Homo sapiens	Mast cell- and dendritic cell-derived exosomes display a specific lipid composition and an unusual membrane organization	Dendritic cells	Lipids	Differential centrifugation Ultracentrifugation	Exosomes
401	Vesiclepedia_19	16302729	Homo sapiens	Purification, characterization and biological significance of tumor-derived exosomes.	Breast cancer cells	Protein	Differential centrifugation Sucrose density gradient Filtration Immunobeads(HER2)	Exosomes
402	Vesiclepedia_137	22723089	Homo sapiens	Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes.	Prostate cancer cells	Protein	Sucrose density gradient	Exosomes
403	Vesiclepedia_142	22723089	Homo sapiens	Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes.	Prostate cancer cells	Protein	Sucrose density gradient	Exosomes
404	Vesiclepedia_126	-	Homo sapiens	Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?	Mesenchymal stem cells	Protein	HPLC	Exosomes
405	Vesiclepedia_469	23029346	Echinostoma caproni	Extracellular Vesicles from Parasitic Helminths Contain Specific Excretory/Secretory Proteins and Are Internalized in Intestinal Host Cells.	Echinostoma caproni	Protein	-	Exosomes/Extracellular vesicles/Microvesicles
406	Vesiclepedia_1070	29937354	Homo sapiens	Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors.	Glioblastoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
407	Vesiclepedia_101	21828046	Rattus norvegicus	The proteo-lipidic composition of exosomes changes during reticulocyte maturation.	Reticulocytes	Protein Lipids	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
408	Vesiclepedia_900	26100252	Homo sapiens	Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts	Chronic lymphocytic leukemia cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
409	Vesiclepedia_812	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Differential centrifugation Filtration ExoQuick Ultracentrifugation	Exosomes
410	Vesiclepedia_797	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Embryonic kidney cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
411	Vesiclepedia_2	3597417	Ovis aries	Vesicle formation during reticulocyte maturation. Association of plasma membrane activities with released vesicles (exosomes).	Reticulocytes	Protein Lipids	Differential centrifugation	Exosomes
412	Vesiclepedia_482	23161513	Homo sapiens	Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.	Colorectal cancer cells	Protein	-	Exosomes
413	Vesiclepedia_916	28687758	Sus scrofa	Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers	Polarised retinal pigmented epithelial cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
414	Vesiclepedia_759	29953723	Salmo salar	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Leukocytes	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
415	Vesiclepedia_216	21293856	Homo sapiens	Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC	Breast cancer cells	Protein	Differential centrifugation Filtration Ultrafiltration Ultracentrifugation Sucrose density gradient	Exosomes
416	Vesiclepedia_1287	20880880	Homo sapiens	Proinflammatory exosomes in bronchoalveolar lavage fluid of patients with sarcoidosis.	Bronchoalveolar lavage fluid	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
417	Vesiclepedia_124	21235781	Homo sapiens	Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages.	Breast milk	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
418	Vesiclepedia_911	28687758	Sus scrofa	Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers	Polarised retinal pigmented epithelial cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
419	Vesiclepedia_1015	22711894	Homo sapiens	Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages.	Macrophages	Protein Lipids	Differential centrifugation Filtration Ultracentrifugation	Exosomes
420	Vesiclepedia_96	21828046	Rattus norvegicus	The proteo-lipidic composition of exosomes changes during reticulocyte maturation.	Reticulocytes	Protein Lipids	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
421	Vesiclepedia_15	17486113	Mus musculus Homo sapiens	Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.	Mast cells	Protein mRNA miRNA	Filtration Ultracentrifugation Sucrose density gradient	Exosomes
422	Vesiclepedia_238	21293856	Homo sapiens	Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC	Ascites	Protein	Differential centrifugation Filtration Ultrafiltration Ultracentrifugation Sucrose density gradient	Exosomes
423	Vesiclepedia_817	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Differential centrifugation Filtration ExoQuick Ultracentrifugation	Exosomes
424	Vesiclepedia_1107	24391718	Homo sapiens	Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.	Prostate epithelial cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
425	Vesiclepedia_787	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Embryonic kidney cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
426	Vesiclepedia_1116	24391718	Homo sapiens	Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.	Prostate epithelial cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
427	Vesiclepedia_329	20304794	Homo sapiens	Functional delivery of viral miRNAs via exosomes	B cells	miRNA	Differential centrifugation	Exosomes
428	Vesiclepedia_672	29953960	Homo sapiens	Exosomes derived from calcium oxalate-exposed macrophages enhance IL-8 production from renal cells, neutrophil migration and crystal invasion through extracellular matrix.	Macrophages	Protein	Microfiltration Differential centrifugation Ultracentrifugation	Exosomes
429	Vesiclepedia_140	22723089	Homo sapiens	Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes.	Prostate cancer cells	Protein	Sucrose density gradient	Exosomes
430	Vesiclepedia_45	18589210	Homo sapiens	MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer.	Serum	Protein miRNA	Ultracentrifugation Immunobeads (EpCAM)	Exosomes
431	Vesiclepedia_826	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Filtration Ultracentrifugation Sucrose density gradient	Exosomes
432	Vesiclepedia_948	28819550	Mus musculus	Effects of storage temperature on airway exosome integrity for diagnostic and functional analyses.	Bronchoalveolar lavage fluid	Protein	Differential centrifugation Ultracentrifugation	Exosomes
433	Vesiclepedia_1077	25104112	Homo sapiens	Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy.	Plasma	miRNA	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Exosomes
434	Vesiclepedia_103	21763319	Homo sapiens	Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells.	Pancreatic adenocarcinoma cells	Protein	Differential centrifugation Filtration Ultrafiltration Ultracentrifugation	Exosomes
435	Vesiclepedia_767	29953723	Salmo salar	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Leukocytes	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
436	Vesiclepedia_556	24069378	Homo sapiens	Proteome profiling of neuroblastoma-derived exosomes reveal the expression of proteins potentially involved in tumor progression.	Neuroblastoma cells	Protein	-	Exosomes/Membrane vesicles
437	Vesiclepedia_29	19109410	Homo sapiens	Proteomic and immunologic analyses of brain tumor exosomes.	Serum	Protein	Differential centrifugation Sucrose density gradient	Exosomes
438	Vesiclepedia_145	22723089	Homo sapiens	Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes.	Prostate cancer cells	Protein	Sucrose density gradient	Exosomes
439	Vesiclepedia_1075	25104112	Homo sapiens	Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy.	Plasma	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Exosomes
440	Vesiclepedia_780	29953723	Salmo salar	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Leukocytes	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
441	Vesiclepedia_667	29956871	Homo sapiens	Expression analysis of extracellular microRNA in bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis	Bronchoalveolar lavage fluid	miRNA	Differential centrifugation Ultracentrifugation Filtration	Exosomes
442	Vesiclepedia_1161	22641613	Homo sapiens	Application of systems biology principles to protein biomarker discovery: urinary exosomal proteome in renal transplantation.	Urine	Protein	Differential centrifugation Ultracentrifugation	Exosomes
443	Vesiclepedia_77	20224111	Homo sapiens	Proteomics analysis of bladder cancer exosomes.	Urine	Protein	Differential centrifugation Sucrose density gradient	Exosomes
444	Vesiclepedia_1046	28725021	Bos taurus	Bovine milk-derived exosomes from colostrum are enriched with proteins implicated in immune response and growth.	Bovine milk	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
445	Vesiclepedia_425	21179422	Mus musculus	Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.	Mast cells	mRNA	-	Exosomes/Nanovesicles
446	Vesiclepedia_1111	24391718	Homo sapiens	Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
447	Vesiclepedia_926	25483805	Homo sapiens	Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties	Embryonic kidney cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
448	Vesiclepedia_1052	29115712	Mus musculus	Proteomic Profiling of Exosomes Secreted by Breast Cancer Cells with Varying Metastatic Potential.	Breast cancer cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
449	Vesiclepedia_766	29953723	Salmo salar	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Leukocytes	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
450	Vesiclepedia_756	28357077	Mus musculus	Circulating osteocyte-derived exosomes contain miRNAs which are enriched in exosomes from MLO-Y4 cells	Plasma	miRNA	Total Exosome Isolation Kit Differential centrifugation	Exosomes
451	Vesiclepedia_477	23056502	Homo sapiens	Identifying mRNA, MicroRNA and Protein Profiles of Melanoma Exosomes.	Melanoma cells	mRNA	-	Exosomes
452	Vesiclepedia_1251	24939845	Homo sapiens	Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein.	Leukemia cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
453	Vesiclepedia_918	28687758	Sus scrofa	Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers	Polarised retinal pigmented epithelial cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
454	Vesiclepedia_818	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Differential centrifugation Filtration ExoQuick Ultracentrifugation	Exosomes
455	Vesiclepedia_1105	24391718	Homo sapiens	Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.	Prostate epithelial cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
456	Vesiclepedia_1160	22641613	Homo sapiens	Application of systems biology principles to protein biomarker discovery: urinary exosomal proteome in renal transplantation.	Urine	Protein	Differential centrifugation Ultracentrifugation	Exosomes
457	Vesiclepedia_1115	24391718	Homo sapiens	Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
458	Vesiclepedia_838	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Differential centrifugation Filtration ExoQuick Ultracentrifugation	Exosomes
459	Vesiclepedia_1275	23489476	Sus scrofa	Boar seminal plasma exosomes: effect on sperm function and protein identification by sequencing.	Seminal plasma	Protein	Differential centrifugation Gel filtration Ultracentrifugation	Exosomes
460	Vesiclepedia_453	22635005	Homo sapiens	Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET.	Melanoma cells	Protein	-	Exosomes
461	Vesiclepedia_1270	24218614	Homo sapiens	Unexpected gain of function for the scaffolding protein plectin due to mislocalization in pancreatic cancer.	Pancreatic adenocarcinoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
462	Vesiclepedia_793	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Embryonic kidney cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
463	Vesiclepedia_1017	22711894	Homo sapiens	Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages.	Macrophages	Protein Lipids	Differential centrifugation Filtration Ultracentrifugation	Exosomes
464	Vesiclepedia_1008	23463506	Homo sapiens	The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes.	T cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
465	Vesiclepedia_927	25483805	Homo sapiens	Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties	Embryonic kidney cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
466	Vesiclepedia_121	21276792	Homo sapiens	Morphologic and proteomic characterization of exosomes released by cultured extravillous trophoblast cells.	Trophoblast cells	Protein	Differential centrifugation Ultrafiltration Ultracentrifugation Density gradient centrifugation	Exosomes
467	Vesiclepedia_1260	24371517	Homo sapiens	Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
468	Vesiclepedia_762	29953723	Salmo salar	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Leukocytes	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
469	Vesiclepedia_49	14582906	Homo sapiens	Exosomes with major histocompatibility complex class II and co-stimulatory molecules are present in human BAL fluid.	Bronchoalveolar lavage fluid	Protein	Differential centrifugation Immunobeads (EpCAM)	Exosomes
470	Vesiclepedia_74	19381331	Homo sapiens	High levels of exosomes expressing CD63 and caveolin-1 in plasma of melanoma patients.	Melanoma cells	Protein	Differential centrifugation	Exosomes
471	Vesiclepedia_410	20052414	Homo sapiens	Nanostructural and transcriptomic analyses of human saliva derived exosomes.	Saliva	mRNA	-	Exosomes/Membrane vesicles
472	Vesiclepedia_1157	20662102	Mus musculus	Proteomic analysis identifies highly antigenic proteins in exosomes from M. tuberculosis-infected and culture filtrate protein-treated macrophages.	Macrophages	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
473	Vesiclepedia_57	17700640	Homo sapiens	CD24 is a marker of exosomes secreted into urine and amniotic fluid.	Urine	Protein	Differential centrifugation Sucrose density gradient	Exosomes
474	Vesiclepedia_508	23511837	Homo sapiens	Differential protein profiling of renal cell carcinoma urinary exosomes.	Urine	Protein	-	Exosomes/Nanovesicles
475	Vesiclepedia_989	25261472	Homo sapiens	Complex N-linked glycans serve as a determinant for exosome/microvesicle cargo recruitment.	Melanoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes/Microvesicles
476	Vesiclepedia_1158	20662102	Mus musculus	Proteomic analysis identifies highly antigenic proteins in exosomes from M. tuberculosis-infected and culture filtrate protein-treated macrophages.	Macrophages	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
477	Vesiclepedia_97	21828046	Rattus norvegicus	The proteo-lipidic composition of exosomes changes during reticulocyte maturation.	Reticulocytes	Protein Lipids	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
478	Vesiclepedia_105	21763319	Homo sapiens	Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells.	Pancreatic adenocarcinoma cells	Protein	Differential centrifugation Filtration Ultrafiltration Ultracentrifugation	Exosomes
479	Vesiclepedia_782	29953723	Salmo salar	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Leukocytes	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
480	Vesiclepedia_739	25157233	Homo sapiens	Extravillous trophoblast cells-derived exosomes promote vascular smooth muscle cell migration.	Placenta	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
481	Vesiclepedia_1253	24939845	Homo sapiens	Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein.	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
482	Vesiclepedia_511	23521563	Homo sapiens	First identification of Ewing's sarcoma-derived extracellular vesicles and exploration of their biological and potential diagnostic implications.	Ewing's sarcoma cells	mRNA	-	Exosomes/Extracellular vesicles
483	Vesiclepedia_546	23983189	Homo sapiens	Characterization of Multiple Myeloma Vesicles by Label-Free Relative Quantitation.	B cells	Protein	-	Exosomes/Extracellular vesicles/Microvesicles
484	Vesiclepedia_1198	27883272	Homo sapiens	Circulating adipocyte-derived exosomal MicroRNAs associated with decreased insulin resistance after gastric bypass.	Serum	miRNA Metabolites	ExoQuick	Exosomes
485	Vesiclepedia_806	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
486	Vesiclepedia_1235	25421927	Heligmosomoides polygyrus	Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity.	Heligmosomoides polygyrus	miRNA Protein	Filtration Ultracentrifugation	Exosomes
487	Vesiclepedia_67	19619303	Homo sapiens	Claudin-containing exosomes in the peripheral circulation of women with ovarian cancer.	Ovarian cancer cells	Protein	Differential centrifugation Sucrose density gradient	Exosomes
488	Vesiclepedia_971	22808001	Homo sapiens	Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment.	Serum	Protein	Filtration ExoQuick	Exosomes
489	Vesiclepedia_354	24115447	Homo sapiens	Comparative proteomics evaluation of plasma exosome isolation techniques and assessment of the stability of exosomes in normal human blood plasma	Plasma	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
490	Vesiclepedia_92	20124479	Rattus norvegicus	Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.	Pancreatic adenocarcinoma cells	Protein mRNA	Differential centrifugation Sucrose density gradient	Exosomes
491	Vesiclepedia_804	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
492	Vesiclepedia_479	23082778	Homo sapiens	Comparative and Targeted Proteomic Analyses of Urinary Microparticles from Bladder Cancer and Hernia Patients.	Urine	Protein	-	Exosomes/Membrane vesicles
493	Vesiclepedia_478	23082778	Homo sapiens	Comparative and Targeted Proteomic Analyses of Urinary Microparticles from Bladder Cancer and Hernia Patients.	Urine	Protein	-	Exosomes/Membrane vesicles
494	Vesiclepedia_130	18309083	Mus musculus	Ceramide triggers budding of exosome vesicles into multivesicular endosomes	Oligodendrocytes	Protein Lipids	Differential centrifugation Sucrose density gradient	Exosomes
495	Vesiclepedia_217	21293856	Homo sapiens	Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC	Serum	Protein	Differential centrifugation Filtration Ultrafiltration Ultracentrifugation Sucrose density gradient	Exosomes
496	Vesiclepedia_978	22808001	Homo sapiens	Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment.	Serum	Protein	Filtration ExoQuick	Exosomes
497	Vesiclepedia_341	20615901	Homo sapiens	Export of microRNAs and microRNA-protective protein by mammalian cells	Epithelial cells	miRNA	Differential centrifugation	Exosomes
498	Vesiclepedia_912	28687758	Sus scrofa	Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers	Polarised retinal pigmented epithelial cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
499	Vesiclepedia_488	23230278	Homo sapiens	Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids.	Colorectal cancer cells	Protein	-	Exosomes/Extracellular vesicles/Microvesicles
500	Vesiclepedia_122	21235781	Homo sapiens	Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages.	Saliva	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
501	Vesiclepedia_789	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Embryonic kidney cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
502	Vesiclepedia_1110	24391718	Homo sapiens	Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
503	Vesiclepedia_1290	19912576	Homo sapiens	HIV Nef is secreted in exosomes and triggers apoptosis in bystander CD4+ T cells.	Lymphoblasts	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
504	Vesiclepedia_677	29951053	Mus musculus	Immunoregulatory Effects of Myeloid-Derived Suppressor Cell Exosomes in Mouse Model of Autoimmune Alopecia Areata.	Dendritic cells	Protein	Ultracentrifugation Density gradient centrifugation	Exosomes
505	Vesiclepedia_26	19109410	Mus musculus	Proteomic and immunologic analyses of brain tumor exosomes.	Brain cancer cells	Protein	Differential centrifugation Sucrose density gradient	Exosomes
506	Vesiclepedia_47	17641064	Homo sapiens	Exosomes with immune modulatory features are present in human breast milk.	B cells	Protein	Differential centrifugation Filtration Sucrose density gradient	Exosomes
507	Vesiclepedia_1012	22711894	Homo sapiens	Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages.	Macrophages	Protein	Differential centrifugation Filtration Ultracentrifugation	Microvesicles/Exosomes
508	Vesiclepedia_5	11145662	Mus musculus	Mast cell-dependent B and T lymphocyte activation is mediated by the secretion of immunologically active exosomes.	Mast cells	Protein	Differential centrifugation	Exosomes
509	Vesiclepedia_1145	23173708	Rattus norvegicus	Wnt3a induces exosome secretion from primary cultured rat microglia.	Primary microglial cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
510	Vesiclepedia_8	12626558	Mus musculus	Mast cell-derived exosomes induce phenotypic and functional maturation of dendritic cells and elicit specific immune responses in vivo.	B cells	Protein	Differential centrifugation	Exosomes
511	Vesiclepedia_59	17700640	Mus musculus	CD24 is a marker of exosomes secreted into urine and amniotic fluid.	Amniotic fluid	Protein	Differential centrifugation Sucrose density gradient	Exosomes
512	Vesiclepedia_1146	23173708	Rattus norvegicus	Wnt3a induces exosome secretion from primary cultured rat microglia.	Primary microglial cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
513	Vesiclepedia_139	22723089	Homo sapiens	Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes.	Prostate cancer cells	Protein	Sucrose density gradient	Exosomes
514	Vesiclepedia_1150	22807456	Homo sapiens	Quantitative proteomic analysis of exosomes from HIV-1-infected lymphocytic cells.	Lymphocytes	Protein	Differential centrifugation Ultracentrifugation	Exosomes
515	Vesiclepedia_1221	27872147	Rattus norvegicus	Primary Human and Rat .-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity.	Insulinoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
516	Vesiclepedia_723	25802036	Homo sapiens	Glioblastoma-derived extracellular vesicles modify the phenotype of monocytic cells.	Glioblastoma cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
517	Vesiclepedia_1118	24391718	Homo sapiens	Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
518	Vesiclepedia_1277	23344851	Rattus norvegicus	Urinary exosomes and diabetic nephropathy: a proteomic approach.	Urine	Protein	Ultracentrifugation	Exosomes
519	Vesiclepedia_125	21059916	Homo sapiens	Human tumor virus utilizes exosomes for intercellular communication.	Nasopharyngeal carcinoma cells	Protein	Differential centrifugation	Exosomes
520	Vesiclepedia_1019	21734072	Mus musculus	Insulinoma-released exosomes or microparticles are immunostimulatory and can activate autoreactive T cells spontaneously developed in nonobese diabetic mice.	Insulinoma cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
521	Vesiclepedia_1217	27872147	Rattus norvegicus	Primary Human and Rat .-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity.	Islets	Protein	Differential centrifugation Ultracentrifugation	Exosomes
522	Vesiclepedia_972	22808001	Homo sapiens	Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment.	Serum	Protein	Filtration ExoQuick	Exosomes
523	Vesiclepedia_1123	24347249	Homo sapiens	Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation ExoQuick	Exosomes
524	Vesiclepedia_690	28170197	Homo sapiens	Enhanced Cardioprotection by Human Endometrium Mesenchymal Stem Cells Driven by Exosomal MicroRNA-21	Bone marrow mesenchymal stem cells	miRNA	Differential centrifugation Filtration Ultracentrifugation	Exosomes
525	Vesiclepedia_1087	25065644	Homo sapiens	Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells.	Duodenal cancer cells	Protein	Differential centrifugation Filtration Ultrafiltration	Exosomes
526	Vesiclepedia_345	22965126	Mus musculus	Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells.	Neuronal cells	miRNA	Differential centrifugation Filtration Ultracentrifugation	Exosomes
527	Vesiclepedia_1020	21734072	Mus musculus	Insulinoma-released exosomes or microparticles are immunostimulatory and can activate autoreactive T cells spontaneously developed in nonobese diabetic mice.	Insulinoma cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
528	Vesiclepedia_1289	19912576	Homo sapiens	HIV Nef is secreted in exosomes and triggers apoptosis in bystander CD4+ T cells.	Cervix carcinoma cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
529	Vesiclepedia_46	17641064	Homo sapiens	Exosomes with immune modulatory features are present in human breast milk.	Breast milk	Protein	Differential centrifugation Filtration Sucrose density gradient	Exosomes
530	Vesiclepedia_507	23511837	Homo sapiens	Differential protein profiling of renal cell carcinoma urinary exosomes.	Urine	Protein	-	Exosomes/Nanovesicles
531	Vesiclepedia_1082	25104112	Homo sapiens	Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy.	Plasma	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Exosomes
532	Vesiclepedia_1084	25104112	Homo sapiens	Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy.	Plasma	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Exosomes
533	Vesiclepedia_1090	25065644	Homo sapiens	Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells.	Duodenal cancer cells	Protein	Differential centrifugation Filtration Ultrafiltration	Exosomes
534	Vesiclepedia_1243	25261722	Homo sapiens	Inflammatory cytokines, interleukin-1 beta and tumor necrosis factor-alpha, upregulated in glioblastoma multiforme, raise the levels of CRYAB in exosomes secreted by U373 glioma cells.	Glioblastoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
535	Vesiclepedia_862	25776846	Homo sapiens	Human thymic epithelial primary cells produce exosomes carrying tissue-restricted antigens	Epithelial cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
536	Vesiclepedia_16	9685355	Homo sapiens	Selective enrichment of tetraspan proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B-lymphocytes.	B cells	Protein	Differential centrifugation Sucrose density gradient	Exosomes
537	Vesiclepedia_50	14582906	Homo sapiens	Exosomes with major histocompatibility complex class II and co-stimulatory molecules are present in human BAL fluid.	Dendritic cells	Protein	Differential centrifugation Immunobeads (EpCAM)	Exosomes
538	Vesiclepedia_120	21362503	Homo sapiens	Protein profile of exosomes from trabecular meshwork cells.	Aqueous humor	Protein	Differential centrifugation Sucrose density gradient	Exosomes
539	Vesiclepedia_337	20976003	Homo sapiens	Selective release of microRNA species from normal and malignant mammary epithelial cells	Breast cancer cells	miRNA	Differential centrifugation Filtration	Exosomes
540	Vesiclepedia_965	25844599	Homo sapiens	Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.	Serum	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
541	Vesiclepedia_1153	22057275	Homo sapiens	Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease.	Neuroblastoma cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
542	Vesiclepedia_1014	22711894	Homo sapiens	Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages.	Macrophages	Protein Lipids	Differential centrifugation Filtration Ultracentrifugation	Exosomes
543	Vesiclepedia_548	24009880	Homo sapiens	Characterization of mRNA and microRNA in human mast cell-derived exosomes and their transfer to other mast cells and blood CD34 progenitor cells.	Mast cells	mRNA	-	Exosomes/Extracellular vesicles
544	Vesiclepedia_349	22285593	Homo sapiens	Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes.	Colorectal cancer cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
545	Vesiclepedia_347	22285593	Homo sapiens	Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes.	Colorectal cancer cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
546	Vesiclepedia_1268	24218614	Homo sapiens	Unexpected gain of function for the scaffolding protein plectin due to mislocalization in pancreatic cancer.	Pancreatic adenocarcinoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
547	Vesiclepedia_982	25458527	Homo sapiens	Benchtop isolation and characterization of functional exosomes by sequential filtration	Breast cancer cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
548	Vesiclepedia_1072	29937354	Homo sapiens	Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors.	Glioblastoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
549	Vesiclepedia_837	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Differential centrifugation Filtration ExoQuick Ultracentrifugation	Exosomes
550	Vesiclepedia_1007	23463506	Mus musculus	The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes.	T cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
551	Vesiclepedia_9	12626558	Mus musculus	Mast cell-derived exosomes induce phenotypic and functional maturation of dendritic cells and elicit specific immune responses in vivo.	Macrophages	Protein	Differential centrifugation	Exosomes
552	Vesiclepedia_492	23333927	Homo sapiens	Characterization and proteomic analysis of ovarian cancer-derived exosomes.	Ovarian cancer cells	Protein	-	Exosomes
553	Vesiclepedia_517	23585443	Homo sapiens	Proteome profiling of exosomes derived from human primary and metastatic colorectal cells reveal differential expression of key metastatic factors and signal transduction components.	Colorectal cancer cells	Protein	-	Exosomes/Membrane vesicles
554	Vesiclepedia_1121	24347249	Homo sapiens	Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation ExoQuick	Exosomes
555	Vesiclepedia_725	25471207	Homo sapiens	Intraluminal proteome and peptidome of human urinary extracellular vesicles.	Urine	Protein	Differential centrifugation Hydrostatic filtration dialysis Ultrafiltration	Exosomes
556	Vesiclepedia_133	19188015	Homo sapiens	Systemic presence and tumor-growth promoting effect of ovarian carcinoma released exosomes	Ovarian cancer cells	Protein Lipids	Differential centrifugation Sucrose density gradient	Exosomes
557	Vesiclepedia_882	29955024	Homo sapiens	Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells	Myeloid leukemia cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
558	Vesiclepedia_1259	24400796	Rattus norvegicus	Exosomal proteins in the aqueous humor as novel biomarkers in patients with neovascular age-related macular degeneration.	Retinal glial cells	Protein	ExoQuick	Exosomes
559	Vesiclepedia_1113	24391718	Homo sapiens	Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
560	Vesiclepedia_487	23230278	Homo sapiens	Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids.	Colorectal cancer cells	Protein	-	Exosomes/Extracellular vesicles/Microvesicles
561	Vesiclepedia_565	26858453	Homo sapiens	Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes	Dendritic cells	Protein	Differential centrifugation Ultracentrifugation OptiPrep density gradient	Exosomes
562	Vesiclepedia_127	21828046	Rattus norvegicus	Proteolipidic Composition of Exosomes Changes during Reticulocyte Maturation	Reticulocytes	Protein Lipids	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
563	Vesiclepedia_693	28170197	Homo sapiens	Enhanced Cardioprotection by Human Endometrium Mesenchymal Stem Cells Driven by Exosomal MicroRNA-21	Bone marrow mesenchymal stem cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
564	Vesiclepedia_447	22444574	Homo sapiens	Proteomic analysis of microvesicles in human saliva by gel electrophoresis with liquid chromatography-mass spectrometry.	Saliva	Protein	-	Exosomes/Microvesicles
565	Vesiclepedia_63	19056867	Homo sapiens	Large-scale proteomics and phosphoproteomics of urinary exosomes.	Urine	Protein	Differential centrifugation	Exosomes
566	Vesiclepedia_737	25220352	Mus musculus	Surface functionalization of exosomes using click chemistry.	Breast cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
567	Vesiclepedia_1000	24079734	Mus musculus	Immunostimulatory activity of murine keratinocyte-derived exosomes.	Keratinocytes	Protein	Differential centrifugation Ultracentrifugation	Exosomes
568	Vesiclepedia_831	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Differential centrifugation Filtration ExoQuick Ultracentrifugation	Exosomes
569	Vesiclepedia_698	28811610	Homo sapiens	Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA.	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
570	Vesiclepedia_902	26100252	Homo sapiens	Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts	Chronic lymphocytic leukemia cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
571	Vesiclepedia_439	22129587	Bos taurus	Bovine milk exosome proteome.	Bovine milk	Protein	-	Exosomes/Membrane vesicles
572	Vesiclepedia_53	14975938	Homo sapiens	Proteomic analysis of exosomes isolated from human malignant pleural effusions.	Malignant pleural effusions	Protein	Differential centrifugation Sucrose density gradient	Exosomes
573	Vesiclepedia_924	25483805	Homo sapiens	Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties	Embryonic kidney cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
574	Vesiclepedia_717	26148937	Homo sapiens	Proteomics profiling of cholangiocarcinoma exosomes: A potential role of oncogenic protein transferring in cancer progression.	Cholangiocytes	Protein	Differential centrifugation Ultracentrifugation Filtration	Exosomes
575	Vesiclepedia_1127	24295599	Mus musculus	Exosomes from myeloid-derived suppressor cells carry biologically active proteins.	Myeloid-derived suppressor cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
576	Vesiclepedia_887	25102470	Homo sapiens	Examination of the specificity of tumor cell derived exosomes with tumor cells in vitro	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
577	Vesiclepedia_93	20124479	Rattus norvegicus	Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.	Pancreatic adenocarcinoma cells	Protein mRNA	Differential centrifugation Sucrose density gradient	Exosomes
578	Vesiclepedia_461	22848702	Homo sapiens	Medulloblastoma exosome proteomics yield functional roles for extracellular vesicles.	Medulloblastoma cells	Protein	-	Exosomes/Membrane vesicles/Extracellular vesicles
579	Vesiclepedia_807	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
580	Vesiclepedia_523	23658846	Mus musculus	Immunomodulatory impact of leishmania-induced macrophage exosomes: a comparative proteomic and functional analysis.	Macrophages	Protein	-	Exosomes
581	Vesiclepedia_3	10545503	Mus musculus	Molecular characterization of dendritic cell-derived exosomes. Selective accumulation of the heat shock protein hsc73.	Dendritic cells	Protein	Differential centrifugation Sucrose density gradient	Exosomes
582	Vesiclepedia_992	24434149	Homo sapiens	In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome.	Ovarian cancer cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
583	Vesiclepedia_1081	25104112	Homo sapiens	Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy.	Plasma	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Exosomes
584	Vesiclepedia_878	29955024	Homo sapiens	Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells	Embryonic kidney cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
585	Vesiclepedia_880	29955024	Homo sapiens	Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells	Myeloid leukemia cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
586	Vesiclepedia_654	28290293	Bos taurus	Comparative proteomic analysis of milk-derived exosomes in human and bovine colostrum and mature milk samples by iTRAQ-coupled LC-MS/MS.	Bovine milk	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Exosomes
587	Vesiclepedia_970	25844599	Homo sapiens	Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.	Serum	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
588	Vesiclepedia_795	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Embryonic kidney cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
589	Vesiclepedia_1080	25104112	Homo sapiens	Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy.	Plasma	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Exosomes
590	Vesiclepedia_1099	24513287	Mus musculus	Lipid synthesis is promoted by hypoxic adipocyte-derived exosomes in 3T3-L1 cells.	adipocytes	Protein	Differential centrifugation Ultracentrifugation Filtration	Exosomes
591	Vesiclepedia_1246	25167841	Homo sapiens	Antibody-coupled monolithic silica microtips for highthroughput molecular profiling of circulating exosomes.	Serum	Protein	CD9 antibody to Mass Spectrometric Immunoassay monolith pipette tips	Exosomes
592	Vesiclepedia_484	23214914	Trypanosoma cruzi	Proteomic analysis of Trypanosoma cruzi secretome: characterization of two populations of extracellular vesicles and soluble proteins.	Epimastigotes	Protein	-	Exosomes/Extracellular vesicles/Ectosomes
593	Vesiclepedia_689	28170197	Homo sapiens	Enhanced Cardioprotection by Human Endometrium Mesenchymal Stem Cells Driven by Exosomal MicroRNA-21	Adipose-derived mesenchymal stem cells	miRNA	Differential centrifugation Filtration Ultracentrifugation	Exosomes
594	Vesiclepedia_25	15111327	Homo sapiens	Proteomic analysis of exosomes secreted by human mesothelioma cells.	Mesothelioma cells	Protein	Differential centrifugation	Exosomes
595	Vesiclepedia_1218	27872147	Homo sapiens	Primary Human and Rat .-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity.	Islets	Protein	Differential centrifugation Ultracentrifugation	Exosomes
596	Vesiclepedia_754	29963269	Homo sapiens	Mining of potential microRNAs with clinical correlation - regulation of syndecan-1 expression by miR-122-5p altered mobility of breast cancer cells and possible correlation with liver injury	Hepatoma cells	Protein	Total Exosome Isolation Kit Differential centrifugation	Exosomes
597	Vesiclepedia_753	29963269	Homo sapiens	Mining of potential microRNAs with clinical correlation - regulation of syndecan-1 expression by miR-122-5p altered mobility of breast cancer cells and possible correlation with liver injury	Hepatoma cells	miRNA	Total Exosome Isolation Kit Differential centrifugation	Exosomes
598	Vesiclepedia_881	29955024	Homo sapiens	Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells	Myeloid leukemia cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
599	Vesiclepedia_437	22106071	Homo sapiens	Proteomic analysis of urine exosomes by multidimensional protein identification technology (MudPIT).	Urine	Protein	-	Exosomes/Membrane vesicles
600	Vesiclepedia_914	28687758	Sus scrofa	Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers	Polarised retinal pigmented epithelial cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
601	Vesiclepedia_14	16081791	Mus musculus	Proteomic analysis of microglia-derived exosomes: metabolic role of the aminopeptidase CD13 in neuropeptide catabolism.	Microglia	Protein	Differential centrifugation Sucrose density gradient	Exosomes
602	Vesiclepedia_98	21828046	Rattus norvegicus	The proteo-lipidic composition of exosomes changes during reticulocyte maturation.	Reticulocytes	Protein Lipids	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
603	Vesiclepedia_551	24009886	Homo sapiens	Cellular stress conditions are reflected in the protein and RNA content of endothelial cell-derived exosomes.	Endothelial cells	Protein	-	Exosomes/Extracellular vesicles
604	Vesiclepedia_106	21763319	Homo sapiens	Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells.	Pancreatic adenocarcinoma cells	Protein	Differential centrifugation Filtration Ultrafiltration Ultracentrifugation	Exosomes
605	Vesiclepedia_735	25285581	Mus musculus	Ubiquitinated proteins in exosomes secreted by myeloid-derived suppressor cells.	Myeloid-derived suppressor cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
606	Vesiclepedia_537	23818640	Homo sapiens	Modulation of B-cell exosome proteins by gamma herpesvirus infection.	B cells	Protein	-	Exosomes/Microvesicles/Oncosomes/Microparticles
607	Vesiclepedia_816	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Differential centrifugation Filtration ExoQuick Ultracentrifugation	Exosomes
608	Vesiclepedia_770	29953723	Salmo salar	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Leukocytes	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
609	Vesiclepedia_811	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Differential centrifugation Filtration ExoQuick Ultracentrifugation	Exosomes
610	Vesiclepedia_237	21293856	Homo sapiens	Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC	Melanoma cells	Protein	Differential centrifugation Filtration Ultrafiltration Ultracentrifugation Sucrose density gradient	Exosomes
611	Vesiclepedia_90	21828046	Rattus norvegicus	The proteo-lipidic composition of exosomes changes during reticulocyte maturation.	Reticulocytes	Protein Lipids	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
612	Vesiclepedia_1132	23861904	Homo sapiens	Exosomal signaling during hypoxia mediates microvascular endothelial cell migration and vasculogenesis.	Placental mesenchymal stem cells	Protein	Differential centrifugation Ultracentrifugation Ultrafiltration Density gradient centrifugation	Exosomes
613	Vesiclepedia_445	22418980	Homo sapiens	A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.	Urine	Protein	-	Exosomes
614	Vesiclepedia_331	19627513	Homo sapiens	Exosomes from human saliva as a source of microRNA biomarkers	Saliva	Protein miRNA	Differential centrifugation Ultracentrifugation	Exosomes
615	Vesiclepedia_519	23585444	Homo sapiens	Identification and characterization of proteins isolated from microvesicles derived from human lung cancer pleural effusions.	Malignant pleural effusions	Protein	-	Exosomes/Microvesicles/Ectosomes/Microparticles
616	Vesiclepedia_55	12147373	Homo sapiens	Malignant effusions and immunogenic tumour-derived exosomes.	Malignant pleural effusions	Protein	Differential centrifugation Sucrose density gradient	Exosomes
617	Vesiclepedia_652	28290293	Homo sapiens	Comparative proteomic analysis of milk-derived exosomes in human and bovine colostrum and mature milk samples by iTRAQ-coupled LC-MS/MS.	Breast milk	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Exosomes
618	Vesiclepedia_975	22808001	Homo sapiens	Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment.	Serum	Protein	Filtration ExoQuick	Exosomes
619	Vesiclepedia_474	23056502	Homo sapiens	Identifying mRNA, MicroRNA and Protein Profiles of Melanoma Exosomes.	Melanoma cells	miRNA	-	Exosomes
620	Vesiclepedia_736	25285581	Mus musculus	Ubiquitinated proteins in exosomes secreted by myeloid-derived suppressor cells.	Myeloid-derived suppressor cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
621	Vesiclepedia_917	28687758	Sus scrofa	Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers	Polarised retinal pigmented epithelial cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
622	Vesiclepedia_785	29953723	Salmo salar	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Epithelial cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
623	Vesiclepedia_432	21751344	Pseudomonas aeruginosa	Proteomic analysis of outer membrane vesicles derived from Pseudomonas aeruginosa.	Pseudomonas aeruginosa	Protein	-	Exosomes/Membrane vesicles
624	Vesiclepedia_1048	28725021	Bos taurus	Bovine milk-derived exosomes from colostrum are enriched with proteins implicated in immune response and growth.	Bovine milk	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
625	Vesiclepedia_1196	27883272	Homo sapiens	Circulating adipocyte-derived exosomal MicroRNAs associated with decreased insulin resistance after gastric bypass.	Plasma	miRNA Metabolites	ExoQuick	Exosomes
626	Vesiclepedia_521	23645497	Canis lupus familiaris	Oncogenic H-Ras reprograms Madin-Darby canine kidney (MDCK) cell-derived exosomal proteins following epithelial-mesenchymal transition.	Kidney cells	Protein	-	Exosomes/Extracellular vesicles
627	Vesiclepedia_679	29951053	Mus musculus	Immunoregulatory Effects of Myeloid-Derived Suppressor Cell Exosomes in Mouse Model of Autoimmune Alopecia Areata.	Myeloid-derived suppressor cells	Protein	Ultracentrifugation Density gradient centrifugation	Exosomes
628	Vesiclepedia_13	15326289	Homo sapiens	Identification and proteomic profiling of exosomes in human urine.	Urine	Protein	Ultracentrifugation	Exosomes
629	Vesiclepedia_553	24009898	Mus musculus	Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes.	Cardiomyocytes	mRNA	-	Exosomes/Extracellular vesicles
630	Vesiclepedia_915	28687758	Sus scrofa	Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers	Polarised retinal pigmented epithelial cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
631	Vesiclepedia_1088	25065644	Homo sapiens	Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells.	Duodenal cancer cells	Protein	Differential centrifugation Filtration Ultrafiltration	Exosomes
632	Vesiclepedia_1124	24347249	Homo sapiens	Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation ExoQuick	Exosomes
633	Vesiclepedia_348	22285593	Homo sapiens	Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes.	Colorectal cancer cells	Protein	Differential centrifugation Filtration Immunoaffinity (EpCAM) Ultracentrifugation	Exosomes
634	Vesiclepedia_549	24009881	Homo sapiens	Quantitative proteomics of extracellular vesicles derived from human primary and metastatic colorectal cancer cells.	Colorectal cancer cells	Protein	-	Exosomes/Extracellular vesicles/Microvesicles/Ectosomes
635	Vesiclepedia_822	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Filtration Ultracentrifugation Sucrose density gradient	Exosomes
636	Vesiclepedia_84	20949044	Homo sapiens	Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line	Lung cancer cells	miRNA	Differential centrifugation Filtration Ultracentrifugation	Exosomes
637	Vesiclepedia_779	29953723	Salmo salar	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Leukocytes	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
638	Vesiclepedia_1233	25469510	Homo sapiens	GAIP interacting protein C-terminus regulates autophagy and exosome biogenesis of pancreatic cancer through metabolic pathways.	Pancreatic cancer cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
639	Vesiclepedia_398	19530224	Homo sapiens	Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes.	Keratinocytes	Protein	-	Exosomes
640	Vesiclepedia_1135	23861904	Homo sapiens	Exosomal signaling during hypoxia mediates microvascular endothelial cell migration and vasculogenesis.	Placental mesenchymal stem cells	Protein	Differential centrifugation Ultracentrifugation Ultrafiltration Density gradient centrifugation	Exosomes
641	Vesiclepedia_493	23333927	Homo sapiens	Characterization and proteomic analysis of ovarian cancer-derived exosomes.	Ovarian cancer cells	Protein	-	Exosomes
642	Vesiclepedia_721	26148937	Homo sapiens	Proteomics profiling of cholangiocarcinoma exosomes: A potential role of oncogenic protein transferring in cancer progression.	Cholangiocarcinoma cells	Protein	Differential centrifugation Ultracentrifugation Filtration	Exosomes
643	Vesiclepedia_23	11231627	Mus musculus	Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming.	Breast cancer cells	Protein	Differential centrifugation Sucrose density gradient	Exosomes
644	Vesiclepedia_988	25261472	Homo sapiens	Complex N-linked glycans serve as a determinant for exosome/microvesicle cargo recruitment.	Melanoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes/Microvesicles
645	Vesiclepedia_214	21364924	Homo sapiens	Thermal- and oxidative stress causes enhanced release of NKG2D ligand-bearing immunosuppressive exosomes in leukemia/lymphoma T and B cells	T cells	Protein	Differential centrifugation Ultracentrifugation Filtration Sucrose density gradient FACS	Exosomes
646	Vesiclepedia_803	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
647	Vesiclepedia_413	20535238	Rattus norvegicus	Candidate biomarkers in exosome-like vesicles purified from rat and mouse urine samples.	Urine	Protein	-	Exosomes
648	Vesiclepedia_885	29955024	Homo sapiens	Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells	Myeloid leukemia cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
649	Vesiclepedia_1185	28042326	Homo sapiens	Exosomes derived from miR-140-5p-overexpressing human synovial mesenchymal stem cells enhance cartilage tissue regeneration and prevent osteoarthritis of the knee in a rat model.	Synovial mesenchymal stem cells	miRNA	Differential centrifugation Filtration Sucrose density gradient	Exosomes
650	Vesiclepedia_271	10903724	Homo sapiens	Follicular dendritic cells carry MHC class II-expressing microvesicles at their surface	B cells	Protein	Differential centrifugation	Exosomes
651	Vesiclepedia_1205	27780738	Homo sapiens	Next-generation sequencing-based small RNA profiling of cerebrospinal fluid exosomes.	Serum	miRNA	Differential centrifugation Ultracentrifugation	Exosomes
652	Vesiclepedia_1154	22057275	Homo sapiens	Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease.	Cerebrospinal fluid	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
653	Vesiclepedia_1089	25065644	Homo sapiens	Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells.	Duodenal cancer cells	Protein	Differential centrifugation Filtration Ultrafiltration	Exosomes
654	Vesiclepedia_110	21601258	Homo sapiens	Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage.	Ascites	Protein miRNA	Differential centrifugation Sucrose density gradient	Exosomes
655	Vesiclepedia_1086	25065644	Homo sapiens	Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells.	Duodenal cancer cells	Protein	Differential centrifugation Filtration Ultrafiltration	Exosomes
656	Vesiclepedia_716	26317203	Homo sapiens	Progression of Osteosarcoma from a Non-Metastatic to a Metastatic Phenotype Is Causally Associated with Activation of an Autocrine and Paracrine uPA Axis.	Osteosarcoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
657	Vesiclepedia_1117	24391718	Homo sapiens	Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.	Prostate epithelial cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
658	Vesiclepedia_678	29951053	Mus musculus	Immunoregulatory Effects of Myeloid-Derived Suppressor Cell Exosomes in Mouse Model of Autoimmune Alopecia Areata.	Myeloid-derived suppressor cells	Protein	Ultracentrifugation Density gradient centrifugation	Exosomes
659	Vesiclepedia_390	19158352	Homo sapiens	Characterization of PKD protein-positive exosome-like vesicles.	Urine	Protein	-	Exosomes/Membrane particles
660	Vesiclepedia_833	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Differential centrifugation Filtration ExoQuick Ultracentrifugation	Exosomes
661	Vesiclepedia_1047	28725021	Bos taurus	Bovine milk-derived exosomes from colostrum are enriched with proteins implicated in immune response and growth.	Bovine milk	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
662	Vesiclepedia_675	29951053	Mus musculus	Immunoregulatory Effects of Myeloid-Derived Suppressor Cell Exosomes in Mouse Model of Autoimmune Alopecia Areata.	Myeloid-derived suppressor cells	Protein	Ultracentrifugation Density gradient centrifugation	Exosomes
663	Vesiclepedia_564	26858453	Homo sapiens	Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes	Dendritic cells	Protein	Differential centrifugation Ultracentrifugation OptiPrep density gradient	Exosomes
664	Vesiclepedia_973	22808001	Homo sapiens	Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment.	Serum	Protein	Filtration ExoQuick	Exosomes