Browse results for content type: protein


 Vesiclepedia IDPubMed IDSpeciesExperiment descriptionSampleIdentificationsIsolation methodsVesicle type
1 Vesiclepedia_602 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Leukemia cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
2 Vesiclepedia_183 21741384 Homo sapiens A filtration-based protocol to isolate human plasma membrane-derived vesicles and exosomes from blood plasma Plasma Protein Differential centrifugation
Filtration
Microvesicles
3 Vesiclepedia_370 16456881 Neisseria meningitidis Outer membrane vesicles from group B Neisseria meningitidis delta gna33 mutant: proteomic and immunological comparison with detergent-derived outer membrane vesicles. Neisseria meningitidis Protein - Membrane vesicles
4 Vesiclepedia_422 21138299 Francisella philomiragia Proteomic characterization and functional analysis of outer membrane vesicles of Francisella novicida suggests possible role in virulence and use as a vaccine. Francisella philomiragia Protein - Membrane vesicles
5 Vesiclepedia_471 23035643 Drosophila melanogaster Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes. Drosophila S2 cells Protein - Exosomes
6 Vesiclepedia_465 22909304 Pseudomonas aeruginosa Identification of proteins associated with the Pseudomonas aeruginosa biofilm extracellular matrix. Pseudomonas aeruginosa Protein - Membrane vesicles
7 Vesiclepedia_249 15741221 Homo sapiens Tissue-factor-bearing microvesicles arise from lipid rafts and fuse with activated platelets to initiate coagulation Monocytes Protein Differential centrifugation Microvesicles
8 Vesiclepedia_195 21668449 Mus musculus SV31 is a Zn2+-binding synaptic vesicle protein PC12 cells Protein Differential centrifugation
Sucrose density gradient
Large dense core vesicles
9 Vesiclepedia_564 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells Protein Differential centrifugation
Ultracenrifugation
OptiPrep density gradient
Exosomes
10 Vesiclepedia_20 17956143 Homo sapiens Proteomic analysis of microvesicles derived from human colorectal cancer cells. Colorectal cancer cells Protein Differential centrifugation
Sucrose density gradient
Diafiltration
Exosomes
11 Vesiclepedia_301 19234131 Homo sapiens Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR Endothelial cells Protein Differential centrifugation Microvesicles
12 Vesiclepedia_211 21368175 Homo sapiens Cancer cell-derived microvesicles induce transformation by transferring tissue transglutaminase and fibronectin to recipient cells Glioma cells Protein Differential centrifugation
Filtration
Microvesicles
13 Vesiclepedia_439 22129587 Bos taurus Bovine milk exosome proteome. Milk Protein - Exosomes/Membrane vesicles
14 Vesiclepedia_40 15908444 Homo sapiens Exosomal-like vesicles are present in human blood plasma. Plasma Protein Differential centrifugation
Filtration
Sucrose density gradient
Exosomes
15 Vesiclepedia_622 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Melanoma cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
16 Vesiclepedia_426 21386968 Acinetobacter baumannii Acinetobacter baumannii secretes cytotoxic outer membrane protein A via outer membrane vesicles. Acinetobacter baumannii Protein - Membrane vesicles
17 Vesiclepedia_631 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Ovarian cancer cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
18 Vesiclepedia_512 23533145 Homo sapiens In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Urine Protein - Exosomes/Microvesicles
19 Vesiclepedia_240 10233897 Homo sapiens Elevated levels of circulating procoagulant microparticles in patients with paroxysmal nocturnal hemoglobinuria and aplastic anemia Platelets Protein
Lipids
Differential centrifugation
FACS
Microparticles
20 Vesiclepedia_278 10233897 Homo sapiens Elevated levels of circulating procoagulant microparticles in patients with paroxysmal nocturnal hemoglobinuria and aplastic anemia Platelets Protein
Lipids
Differential centrifugation
FACS
Microparticles
21 Vesiclepedia_524 23658846 Mus musculus Immunomodulatory impact of leishmania-induced macrophage exosomes: a comparative proteomic and functional analysis. Macrophages Protein - Exosomes
22 Vesiclepedia_245 9126269 Homo sapiens Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations T cells Protein
mRNA
Differential centrifugation
Sucrose density gradient
Microvesicles
23 Vesiclepedia_50 14582906 Homo sapiens Exosomes with major histocompatibility complex class II and co-stimulatory molecules are present in human BAL fluid. Dendritic cells Protein Differential centrifugation
Immunobeads (EpCAM)
Exosomes
24 Vesiclepedia_313 15499615 Homo sapiens Microvesicles derived from activated platelets induce metastasis and angiogenesis in lung cancer Lung cancer cells Protein Differential centrifugation
FACS
Microvesicles
25 Vesiclepedia_610 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Lung cancer cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
26 Vesiclepedia_171 21859146 Homo sapiens Identification of a conserved glycan signature for microvesicles Colorectal cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Microvesicles
27 Vesiclepedia_395 19413345 Homo sapiens Proteomic analysis of malignant B-cell derived microparticles reveals CD148 as a potentially useful antigenic biomarker for mantle cell lymphoma diagnosis. B cells Protein - Microparticles
28 Vesiclepedia_544 23977379 Listeria monocytogenes Transcription Factor σ(B) Plays an Important Role in the Production of Extracellular Membrane-Derived Vesicles in Listeria monocytogenes. Listeria monocytogenes Protein - Membrane vesicles
29 Vesiclepedia_588 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Colon cancer cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
30 Vesiclepedia_108 21601258 Homo sapiens Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage. Ascites Protein
miRNA
Differential centrifugation
Sucrose density gradient
Immunobeads (EpCAM, CD24)
Exosomes
31 Vesiclepedia_535 23818640 Homo sapiens Modulation of B-cell exosome proteins by gamma herpesvirus infection. B cells Protein - Exosomes/Microvesicles/Oncosomes/Microparticles
32 Vesiclepedia_550 24009881 Homo sapiens Quantitative proteomics of extracellular vesicles derived from human primary and metastatic colorectal cancer cells. Colorectal cancer cells Protein - Exosomes/Extracellular vesicles/Microvesicles/Ectosomes
33 Vesiclepedia_173 21859146 Homo sapiens Identification of a conserved glycan signature for microvesicles Breast milk Protein Differential centrifugation
Filtration
Ultracentrifugation
Microvesicles
34 Vesiclepedia_604 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Leukemia cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
35 Vesiclepedia_200 21606166 Homo sapiens Blast-derived microvesicles in sera from patients with acute myeloid leukemia suppress natural killer cell function via membrane-associated transforming growth factor-beta1 Serum Protein Size exclusion chromatography
Ultracentrifugation
Microvesicles
36 Vesiclepedia_599 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Kidney cancer cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
37 Vesiclepedia_138 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells Protein Sucrose density gradient Exosomes
38 Vesiclepedia_480 23161513 Homo sapiens Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS. Colorectal cancer cells Protein - Exosomes
39 Vesiclepedia_381 18346024 Homo sapiens The proteome of red cell membranes and vesicles during storage in blood bank conditions. Red blood cells Protein - Microvesicles/Nanovesicles
40 Vesiclepedia_275 12021310 Homo sapiens Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles Melanoma cells Protein Differential centrifugation
Ultracentrifugation
Microvesicles
41 Vesiclepedia_153 22022598 Homo sapiens Syncytiotrophoblast microvesicles released from pre-eclampsia placentae exhibit increased tissue factor activity Placenta Protein Differential centrifugation Microvesicles
42 Vesiclepedia_158 21630462 Homo sapiens Proteomic analysis of microvesicles derived from human colorectal cancer ascites Ascites Protein Differential centrifugation
Sucrose density gradient
OptiPrep density gradient
Microvesicles
43 Vesiclepedia_306 16342139 Homo sapiens Proteomic analysis of malignant lymphocyte membrane microparticles using double ionization coverage optimization T cells Protein Differential centrifugation Microparticles
44 Vesiclepedia_18 11907077 Homo sapiens TCR activation of human T cells induces the production of exosomes bearing the TCR/CD3/zeta complex. T cells Protein Filtration
Ultracentrifugation
Exosomes
45 Vesiclepedia_296 12796750 Homo sapiens High levels of circulating endothelial microparticles in patients with acute coronary syndromes Plasma Protein Differential centrifugation
FACS
Microparticles
46 Vesiclepedia_152 22064971 Homo sapiens Oxidized low-density lipoprotein-dependent platelet-derived microvesicles trigger procoagulant effects and amplify oxidative stress Platelets Protein Differential centrifugation Microvesicles
47 Vesiclepedia_72 19801663 Homo sapiens Microenvironmental pH is a key factor for exosome traffic in tumor cells. Melanoma cells Protein
Lipids
Differential centrifugation Exosomes
48 Vesiclepedia_468 23000592 Homo sapiens In-depth analysis of the secretome identifies three major independent secretory pathways in differentiating human myoblasts. Neonatal myoblast cells Protein - Microvesicles/Nanovesicles
49 Vesiclepedia_539 23853596 Trichomonas vaginalis Trichomonas vaginalis Exosomes Deliver Cargo to Host Cells and Mediate Host∶Parasite Interactions. Trichomonas vaginalis Protein - Exosomes/Microvesicles
50 Vesiclepedia_1 6307529 Ovis aries Fate of the transferrin receptor during maturation of sheep reticulocytes in vitro: selective externalization of the receptor. Reticulocytes Protein - Exosomes
51 Vesiclepedia_407 19834908 Staphylococcus aureus Gram-positive bacteria produce membrane vesicles: proteomics-based characterization of Staphylococcus aureus-derived membrane vesicles. Staphylococcus aureus Protein - Membrane vesicles
52 Vesiclepedia_192 21635979 Mus musculus Proteomic characterization of thymocyte-derived microvesicles and apoptotic bodies in BALB/c mice Thymus Protein Differential centrifugation
Filtration
Apoptotic bodies
53 Vesiclepedia_300 19234131 Homo sapiens Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR Epidermoid carcinoma cells Protein Differential centrifugation Microvesicles
54 Vesiclepedia_81 20458337 Homo sapiens MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 3 B cells Protein Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Exosomes
55 Vesiclepedia_335 20976003 Homo sapiens Selective release of microRNA species from normal and malignant mammary epithelial cells Breast cancer cells Protein
miRNA
Differential centrifugation
Filtration
Exosomes
56 Vesiclepedia_270 10903724 Homo sapiens Follicular dendritic cells carry MHC class II-expressing microvesicles at their surface Dendritic cells Protein - Microvesicles
57 Vesiclepedia_83 20949044 Homo sapiens Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line Lung cancer cells Protein
miRNA
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
58 Vesiclepedia_570 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells Protein Differential centrifugation
Ultracenrifugation
Immunobeads (CD63 PD)
Extracellular vesicle
59 Vesiclepedia_11 12519789 Homo sapiens Proteomic and biochemical analyses of human B cell-derived exosomes. Potential implications for their function and multivesicular body formation. B cells Protein
Lipids
Differential centrifugation
Sucrose density gradient
Exosomes
60 Vesiclepedia_619 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Melanoma cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
61 Vesiclepedia_632 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Ovarian cancer cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
62 Vesiclepedia_82 20949044 Homo sapiens Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line Stomach cancer cells Protein
miRNA
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
63 Vesiclepedia_608 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Lung cancer cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
64 Vesiclepedia_61 17133577 Mus musculus Association of citrullinated proteins with synovial exosomes. Synovial fluid Protein Differential centrifugation
Sucrose density gradient
Exosomes
65 Vesiclepedia_41 15908444 Homo sapiens Exosomal-like vesicles are present in human blood plasma. Mast cells Protein Differential centrifugation
Filtration
Sucrose density gradient
Exosomes
66 Vesiclepedia_623 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Melanoma cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
67 Vesiclepedia_447 22444574 Homo sapiens Proteomic analysis of microvesicles in human saliva by gel electrophoresis with liquid chromatography-mass spectrometry. Saliva Protein - Exosomes/Microvesicles
68 Vesiclepedia_73 18494037 Mus musculus Difference gel electrophoresis analysis of Ras-transformed fibroblast cell-derived exosomes. Embryonic fibroblast cells Protein Differential centrifugation Exosomes
69 Vesiclepedia_542 23935504 Homo sapiens A Novel Role for Pro-Coagulant Microvesicles in the Early Host Defense against Streptococcus pyogenes. Peripheral blood mononucelar cells Protein - Microvesicles
70 Vesiclepedia_541 23935504 Homo sapiens A Novel Role for Pro-Coagulant Microvesicles in the Early Host Defense against Streptococcus pyogenes. Peripheral blood mononucelar cells Protein - Microvesicles
71 Vesiclepedia_79 20458337 Homo sapiens MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 1 B cells Protein Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Exosomes
72 Vesiclepedia_473 23056467 Homo sapiens Cause or Effect of Arteriogenesis: Compositional Alterations of Microparticles from CAD Patients Undergoing External Counterpulsation Therapy. Blood Protein - Microparticles
73 Vesiclepedia_549 24009881 Homo sapiens Quantitative proteomics of extracellular vesicles derived from human primary and metastatic colorectal cancer cells. Colorectal cancer cells Protein - Exosomes/Extracellular vesicles/Microvesicles/Ectosomes
74 Vesiclepedia_466 22966805 Acinetobacter baumannii Extracellular proteome of a highly invasive multidrug-resistant clinical strain of Acinetobacter baumannii. Acinetobacter baumannii Protein - Membrane vesicles
75 Vesiclepedia_582 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Brain cancer cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
76 Vesiclepedia_98 21828046 Rattus norvegicus The proteo-lipidic composition of exosomes changes during reticulocyte maturation. Reticulocytes Protein
Lipids
Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Exosomes
77 Vesiclepedia_392 19351151 Mus musculus Characterization of vesicles secreted from insulinoma NIT-1 cells. Pancreatic cells Protein - Exosomes
78 Vesiclepedia_486 23230278 Homo sapiens Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids. Colorectal cancer cells Protein - Exosomes/Extracellular vesicles/Microvesicles
79 Vesiclepedia_403 19548909 Homo sapiens Differential stimulation of monocytic cells results in distinct populations of microparticles. Monocytes Protein - Microparticles
80 Vesiclepedia_274 12021310 Homo sapiens Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles Melanoma cells Protein Differential centrifugation
Ultracentrifugation
Microvesicles
81 Vesiclepedia_31 10572093 Homo sapiens Activated platelets release two types of membrane vesicles: microvesicles by surface shedding and exosomes derived from exocytosis of multivesicular bodies and alpha-granules. Platelets Protein Differential centrifugation
Sucrose density gradient
Exosomes
82 Vesiclepedia_373 17787032 Escherichia coli Global proteomic profiling of native outer membrane vesicles derived from Escherichia coli. Escherichia coli Protein - Membrane vesicles
83 Vesiclepedia_572 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells Protein Differential centrifugation
Ultracenrifugation
Immunobeads (CD81 PD)
Extracellular vesicle
84 Vesiclepedia_629 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Ovarian cancer cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
85 Vesiclepedia_78 20224111 Homo sapiens Proteomics analysis of bladder cancer exosomes. Urine Protein Differential centrifugation
Sucrose density gradient
Exosomes
86 Vesiclepedia_418 21049385 Homo sapiens The plasma microparticle proteome. Plasma Protein - Microparticles
87 Vesiclepedia_288 12196479 Homo sapiens Type 1 and type 2 diabetic patients display different patterns of cellular microparticles Plasma Protein
Lipids
Differential centrifugation
FACS
Microparticles
88 Vesiclepedia_231 2294986 Homo sapiens Direct detection of activated platelets and platelet-derived microparticles in humans Plasma Protein FACS Microparticles
89 Vesiclepedia_22 15940614 Homo sapiens Human colorectal cancer cells induce T-cell death through release of proapoptotic microvesicles: role in immune escape. Colorectal cancer cells Protein Differential centrifugation Exosomes
90 Vesiclepedia_215 21364924 Homo sapiens Thermal- and oxidative stress causes enhanced release of NKG2D ligand-bearing immunosuppressive exosomes in leukemia/lymphoma T and B cells B cells Protein Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Exosomes
91 Vesiclepedia_368 16103114 Neisseria meningitidis Biochemical and functional characterization of membrane blebs purified from Neisseria meningitidis serogroup B. Neisseria meningitidis Protein - Membrane vesicles
92 Vesiclepedia_294 2071604 Homo sapiens Evidence that agonist-induced activation of calpain causes the shedding of procoagulant-containing microvesicles from the membrane of aggregating platelets Platelets Protein Differential centrifugation
Filtration
Microvesicles
93 Vesiclepedia_311 22148876 Homo sapiens Proteomic analysis of microvesicles derived from human mesenchymal stem cells Mesenchymal stem cells Protein Differential centrifugation
Ultrafiltration
Ultracentrifugation
Sucrose density gradient
Optiprep density gradient
Microvesicles
94 Vesiclepedia_592 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Colon cancer cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
95 Vesiclepedia_543 23977379 Listeria monocytogenes Transcription Factor σ(B) Plays an Important Role in the Production of Extracellular Membrane-Derived Vesicles in Listeria monocytogenes. Listeria monocytogenes Protein - Membrane vesicles
96 Vesiclepedia_484 23214914 Trypanosoma cruzi Proteomic analysis of Trypanosoma cruzi secretome: characterization of two populations of extracellular vesicles and soluble proteins. Epimastigotes Protein - Exosomes/Extracellular vesicles/Ectosomes
97 Vesiclepedia_88 20949044 Homo sapiens Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line Stomach cancer cells Protein
miRNA
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
98 Vesiclepedia_80 20458337 Homo sapiens MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis -Sample 2 B cells Protein Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Exosomes
99 Vesiclepedia_415 20687614 Myxococcus xanthus Profiling the outer membrane proteome during growth and development of the social bacterium Myxococcus xanthus by selective biotinylation and analyses of outer membrane vesicles. Myxococcus xanthus Protein - Membrane vesicles
100 Vesiclepedia_605 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Leukemia cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
101 Vesiclepedia_71 19801663 Homo sapiens Microenvironmental pH is a key factor for exosome traffic in tumor cells. Melanoma cells Protein
Lipids
Differential centrifugation
Sucrose density gradient
Exosomes
102 Vesiclepedia_7 12626558 Mus musculus Mast cell-derived exosomes induce phenotypic and functional maturation of dendritic cells and elicit specific immune responses in vivo. Mast cells Protein Differential centrifugation Exosomes
103 Vesiclepedia_49 14582906 Homo sapiens Exosomes with major histocompatibility complex class II and co-stimulatory molecules are present in human BAL fluid. Bronchoalveolar lavage fluid Protein Differential centrifugation
Immunobeads (EpCAM)
Exosomes
104 Vesiclepedia_115 21505438 Homo sapiens Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells. T cells Protein
miRNA
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
105 Vesiclepedia_191 21635979 Mus musculus Proteomic characterization of thymocyte-derived microvesicles and apoptotic bodies in BALB/c mice Thymus Protein Differential centrifugation
Filtration
Microvesicles
106 Vesiclepedia_501 23410224 Neisseria meningitidis Quantitative proteomics reveals distinct differences in the protein content of outer membrane vesicle vaccines. Neisseria meningitidis Protein - Membrane vesicles
107 Vesiclepedia_615 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Lung cancer cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
108 Vesiclepedia_127 21828046 Rattus norvegicus Proteolipidic Composition of Exosomes Changes during Reticulocyte Maturation Reticulocytes Protein
Lipids
Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Exosomes
109 Vesiclepedia_27 19109410 Homo sapiens Proteomic and immunologic analyses of brain tumor exosomes. Medulloblastoma cells Protein Differential centrifugation
Sucrose density gradient
Exosomes
110 Vesiclepedia_198 21555566 Homo sapiens Multiple recognition assay reveals prostasomes as promising plasma biomarkers for prostate cancer Plasma Protein Differential centrifugation
Ultracentrifugation
Gel chromatography
Microvesicles
111 Vesiclepedia_56 12147373 Homo sapiens Malignant effusions and immunogenic tumour-derived exosomes. Ascites Protein Differential centrifugation
Sucrose density gradient
Exosomes
112 Vesiclepedia_62 17133577 Mus musculus Association of citrullinated proteins with synovial exosomes. Synovial fluid Protein Differential centrifugation
Sucrose density gradient
Exosomes
113 Vesiclepedia_174 21842121 Mus musculus Oligodendroglioma cells shed microvesicles which contain TRAIL as well as molecular chaperones and induce cell death in astrocytes Oligodendrocytes Protein Differential centrifugation Microvesicles
114 Vesiclepedia_590 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Colon cancer cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
115 Vesiclepedia_179 20686450 Homo sapiens Comparison of three methods for isolation of urinary microvesicles to identify biomarkers of nephrotic syndrome Urine Protein Differential centrifugation
Ultracentrifugation
Microvesicles
116 Vesiclepedia_234 10648405 Homo sapiens Cellular origin and procoagulant properties of microparticles in meningococcal sepsis Plasma Protein Differential centrifugation
FACS
Microparticles
117 Vesiclepedia_430 21595033 Homo sapiens Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy. Urine Protein - Exosomes
118 Vesiclepedia_60 17700640 Mus musculus CD24 is a marker of exosomes secreted into urine and amniotic fluid. Urine Protein Differential centrifugation
Sucrose density gradient
Exosomes
119 Vesiclepedia_258 9126269 Homo sapiens Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations T lymphoblastic leukemia Protein Differential centrifugation
Sucrose density gradient
Microvesicles
120 Vesiclepedia_481 23161513 Homo sapiens Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS. Colorectal cancer cells Protein - Exosomes
121 Vesiclepedia_17 11907077 Homo sapiens TCR activation of human T cells induces the production of exosomes bearing the TCR/CD3/zeta complex. T cells Protein Filtration
Ultracentrifugation
Exosomes
122 Vesiclepedia_241 16192427 Homo sapiens Circulating endothelial microparticles are associated with vascular dysfunction in patients with end-stage renal failure Plasma Protein Differential centrifugation
FACS
Microparticles
123 Vesiclepedia_379 18346024 Homo sapiens The proteome of red cell membranes and vesicles during storage in blood bank conditions. Red blood cells Protein - Microvesicles/Nanovesicles
124 Vesiclepedia_54 14975938 Homo sapiens Proteomic analysis of exosomes isolated from human malignant pleural effusions. Malignant pleural effusions Protein Differential centrifugation
Sucrose density gradient
Exosomes
125 Vesiclepedia_121 21276792 Homo sapiens Morphologic and proteomic characterization of exosomes released by cultured extravillous trophoblast cells. Trophoblast cells Protein Differential centrifugation
Ultrafiltration
Ultracentrifugation
Sucrose density gradient
Exosomes
126 Vesiclepedia_470 23029346 Fasciola hepatica Extracellular Vesicles from Parasitic Helminths Contain Specific Excretory/Secretory Proteins and Are Internalized in Intestinal Host Cells. Fasciola hepatica Protein - Exosomes/Extracellular vesicles/Microvesicles
127 Vesiclepedia_178 20686450 Homo sapiens Comparison of three methods for isolation of urinary microvesicles to identify biomarkers of nephrotic syndrome Urine Protein Differential centrifugation
Ultrafiltration
Microvesicles
128 Vesiclepedia_446 22428779 Klebsiella pneumoniae Klebsiella pneumoniae secretes outer membrane vesicles that induce the innate immune response. Klebsiella pneumoniae Protein - Membrane vesicles
129 Vesiclepedia_598 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Kidney cancer cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
130 Vesiclepedia_384 18482993 Homo sapiens Protein composition of human epididymosomes collected during surgical vasectomy reversal: a proteomic and genomic approach. Epididymal fluid Protein - Prostasomes
131 Vesiclepedia_577 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Breast cancer cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
132 Vesiclepedia_442 22288420 Paracoccidioides brasiliensis Vesicle and vesicle-free extracellular proteome of Paracoccidioides brasiliensis: comparative analysis with other pathogenic fungi. Paracoccidioides brasiliensis Protein - Extracellular vesicles
133 Vesiclepedia_69 19812188 Rattus norvegicus Immature dendritic cell-derived exosomes rescue septic animals via milk fat globule epidermal growth factor VIII. Dendritic cells Protein Differential centrifugation
Sucrose density gradient
Exosomes
134 Vesiclepedia_611 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Lung cancer cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
135 Vesiclepedia_401 19548909 Homo sapiens Differential stimulation of monocytic cells results in distinct populations of microparticles. Monocytes Protein - Microparticles
136 Vesiclepedia_523 23658846 Mus musculus Immunomodulatory impact of leishmania-induced macrophage exosomes: a comparative proteomic and functional analysis. Macrophages Protein - Exosomes
137 Vesiclepedia_259 18425114 Homo sapiens Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells Glioma cells Protein Differential centrifugation
Ultracentrifugation
Microvesicles
138 Vesiclepedia_428 21515422 Homo sapiens Proteomic characterization of biogenesis and functions of matrix vesicles released from mineralizing human osteoblast-like cells. Osteosarcoma cells Protein - Matrix vesicles
139 Vesiclepedia_39 15210972 Mus musculus Cells release prions in association with exosomes. Mov neuroglial cell Protein Differential centrifugation
Sucrose density gradient
Exosomes
140 Vesiclepedia_521 23645497 Canis lupus familiaris Oncogenic H-Ras reprograms Madin-Darby canine kidney (MDCK) cell-derived exosomal proteins following epithelial-mesenchymal transition. Madin-Darby canine kidney cell (MDCK) Protein - Exosomes/Extracellular vesicles
141 Vesiclepedia_522 23645497 Canis lupus familiaris Oncogenic H-Ras reprograms Madin-Darby canine kidney (MDCK) cell-derived exosomal proteins following epithelial-mesenchymal transition. Madin-Darby canine kidney cell (MDCK) Protein - Exosomes/Extracellular vesicles
142 Vesiclepedia_224 10393703 Homo sapiens In vitro generation of endothelial microparticles and possible prothrombotic activity in patients with lupus anticoagulant Plasma Protein Differential centrifugation Microparticles
143 Vesiclepedia_256 9126269 Homo sapiens Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations Burkitt's lymphoma Protein Differential centrifugation
Sucrose density gradient
Microvesicles
144 Vesiclepedia_616 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Lung cancer cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
145 Vesiclepedia_184 21672581 Rattus norvegicus Oxygen-glucose deprivation increases the enzymatic activity and the microvesicle-mediated release of ectonucleotidases in the cells composing the blood-brain barrier Astrocytes Protein Differential centrifugation Microvesicles
146 Vesiclepedia_43 17076679 Homo sapiens Specific isolation of placenta-derived exosomes from the circulation of pregnant women and their immunoregulatory consequences. Plasma Protein Size exclusion chromatography
Ultracentrifugation
Immunobeads (CD3, CD19, CD56, CD83, PLAP)
Exosomes
147 Vesiclepedia_526 23660474 Homo sapiens Heterogeneity in neutrophil microparticles reveals distinct proteome and functional properties. Neutrophils Protein - Microparticles
148 Vesiclepedia_253 9126269 Homo sapiens Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations T4-lymphoblastoid cells Protein Differential centrifugation
Sucrose density gradient
Microvesicles
149 Vesiclepedia_91 21252909 Homo sapiens Diacylglycerol kinase a regulates the formation and polarisation of mature multivesicular bodies involved in the secretion of Fas ligand-containing exosomes in T lymphocytes T cells Protein
Lipids
Differential centrifugation
Ultracentrifugation
Exosomes
150 Vesiclepedia_36 19367702 Mus musculus Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes. Hepatocytes Protein Differential centrifugation
Filtration
Exosomes
151 Vesiclepedia_597 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Kidney cancer cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
152 Vesiclepedia_369 16212402 Homo sapiens The platelet microparticle proteome. Platelets Protein - Microparticles
153 Vesiclepedia_260 10888925 Homo sapiens Transfer of the chemokine receptor CCR5 between cells by membrane-derived microparticles: a mechanism for cellular human immunodeficiency virus 1 infection Mononuclear cells Protein Differential centrifugation
Filtration
Microparticles
154 Vesiclepedia_376 18346024 Homo sapiens The proteome of red cell membranes and vesicles during storage in blood bank conditions. Red blood cells Protein - Microvesicles/Nanovesicles
155 Vesiclepedia_193 21575145 Homo sapiens Microvesicle-mediated release of soluble LH/hCG receptor (LHCGR) from transfected cells and placenta explants Placenta Protein Differential centrifugation
Ultracentrifugation
Microvesicles
156 Vesiclepedia_291 15072974 Rattus norvegicus Endothelium-derived microparticles impair endothelial function in vitro Endothelial cells Protein Differential centrifugation
Ultracentrifugation
FACS
Microparticles
157 Vesiclepedia_568 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells Protein Differential centrifugation
Ultracenrifugation
Immunobeads (CD9 PD)
Extracellular vesicle
158 Vesiclepedia_310 22148876 Homo sapiens Proteomic analysis of microvesicles derived from human mesenchymal stem cells Mesenchymal stem cells Protein Differential centrifugation
Ultrafiltration
Ultracentrifugation
Sucrose density gradient
Optiprep density gradient
Microvesicles
159 Vesiclepedia_187 22116803 Equus caballus Cell-Secreted Vesicles in Equine Ovarian Follicular Fluid Contain miRNAs and Proteins: A Possible New Form of Cell Communication Within the Ovarian Follicle Serum Protein Differential centrifugation
Exoquick
Exosomes
160 Vesiclepedia_100 21828046 Rattus norvegicus The proteo-lipidic composition of exosomes changes during reticulocyte maturation. Reticulocytes Protein
Lipids
Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Exosomes
161 Vesiclepedia_130 18309083 Mus musculus Ceramide triggers budding of exosome vesicles into multivesicular endosomes Oligodendrocytes Protein
Lipids
Differential centrifugation
Sucrose density gradient
Exosomes
162 Vesiclepedia_458 22740476 Homo sapiens Restoration of full-length APC protein in SW480 colon cancer cells induces exosome-mediated secretion of DKK-4. Colorectal cancer cells Protein - Exosomes
163 Vesiclepedia_261 12805058 Homo sapiens Sickle blood contains tissue factor-positive microparticles derived from endothelial cells and monocytes Plasma Protein
Lipids
Differential centrifugation
Ultracentrifugation
FACS
Microparticles
164 Vesiclepedia_285 12796750 Homo sapiens High levels of circulating endothelial microparticles in patients with acute coronary syndromes Plasma Protein Differential centrifugation
FACS
Microparticles
165 Vesiclepedia_102 21082674 Homo sapiens Comprehensive analysis of low-abundance proteins in human urinary exosomes using peptide ligand library technology, peptide OFFGEL fractionation and nanoHPLC-chip-MS/MS. Urine Protein Differential centrifugation
Ultracentrifugation
Exosomes
166 Vesiclepedia_74 19381331 Homo sapiens High levels of exosomes expressing CD63 and caveolin-1 in plasma of melanoma patients. Melanoma cells Protein Differential centrifugation Exosomes
167 Vesiclepedia_51 14975938 Homo sapiens Proteomic analysis of exosomes isolated from human malignant pleural effusions. Malignant pleural effusions Protein Differential centrifugation
Sucrose density gradient
Exosomes
168 Vesiclepedia_76 20224111 Homo sapiens Proteomics analysis of bladder cancer exosomes. Bladder cancer cells Protein Differential centrifugation
Sucrose density gradient
Exosomes
169 Vesiclepedia_273 12021310 Homo sapiens Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles T cells Protein Differential centrifugation
Ultracentrifugation
Microvesicles
170 Vesiclepedia_124 21235781 Homo sapiens Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages. Breast milk Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
171 Vesiclepedia_25 15111327 Homo sapiens Proteomic analysis of exosomes secreted by human mesothelioma cells. Mesothelioma cells Protein Differential centrifugation Exosomes
172 Vesiclepedia_117 21505438 Homo sapiens Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells. Dendritic cells Protein
miRNA
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
173 Vesiclepedia_180 20686450 Homo sapiens Comparison of three methods for isolation of urinary microvesicles to identify biomarkers of nephrotic syndrome Urine Protein Differential centrifugation
Ultracentrifugation
Size exclusion chromatography
Filtration
Microvesicles
174 Vesiclepedia_144 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells Protein Sucrose density gradient Exosomes
175 Vesiclepedia_114 21557262 Homo sapiens Proteomic identification of exosomal LRG1: A potential urinary biomarker for detecting NSCLC. Urine Protein Differential centrifugation
Ultracentrifugation
Exosomes
176 Vesiclepedia_92 20124479 Rattus norvegicus Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation. Pancreatic adenocarcinoma cells Protein
mRNA
Differential centrifugation
Sucrose density gradient
Exosomes
177 Vesiclepedia_189 21741384 Homo sapiens A filtration-based protocol to isolate human plasma membrane-derived vesicles and exosomes from blood plasma Plasma Protein Differential centrifugation
Filtration
Exosomes
178 Vesiclepedia_346 22965126 Mus musculus Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells. Neuronal cells Protein
miRNA
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
179 Vesiclepedia_606 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Leukemia cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
180 Vesiclepedia_580 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Brain cancer cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
181 Vesiclepedia_333 20976003 Homo sapiens Selective release of microRNA species from normal and malignant mammary epithelial cells Breast cancer cells Protein
miRNA
Differential centrifugation
Filtration
Exosomes
182 Vesiclepedia_624 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Melanoma cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
183 Vesiclepedia_161 21901833 Drosophila melanogaster Proteomics analyses of microvesicles released by Drosophila Kc167 and S2 cells Hematocytes Protein
PTM Ubiquitination
Differential centrifugation
Sucrose density gradient
Ultracentrifugation
Microvesicles
184 Vesiclepedia_595 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Kidney cancer cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
185 Vesiclepedia_607 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Leukemia cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
186 Vesiclepedia_586 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Brain cancer cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
187 Vesiclepedia_290 12196479 Homo sapiens Type 1 and type 2 diabetic patients display different patterns of cellular microparticles Plasma Protein
Lipids
Differential centrifugation
FACS
Microparticles
188 Vesiclepedia_272 8896411 Homo sapiens High shear stress can initiate both platelet aggregation and shedding of procoagulant containing microparticles Platelets Protein
Lipids
Differential centrifugation
FACS
Microparticles
189 Vesiclepedia_96 21828046 Rattus norvegicus The proteo-lipidic composition of exosomes changes during reticulocyte maturation. Reticulocytes Protein
Lipids
Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Exosomes
190 Vesiclepedia_382 18373357 Homo sapiens Isolation and identification of potential urinary microparticle biomarkers of bladder cancer. Urine Protein - Microparticles
191 Vesiclepedia_336 20976003 Homo sapiens Selective release of microRNA species from normal and malignant mammary epithelial cells Breast cancer cells Protein
miRNA
Differential centrifugation
Filtration
Exosomes
192 Vesiclepedia_399 19530224 Homo sapiens Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes. Keratinocytes Protein - Exosomes
193 Vesiclepedia_265 18425114 Homo sapiens Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells Endothelial cells Protein Differential centrifugation
Ultracentrifugation
Microvesicles
194 Vesiclepedia_289 12196479 Homo sapiens Type 1 and type 2 diabetic patients display different patterns of cellular microparticles Plasma Protein
Lipids
Differential centrifugation
FACS
Microparticles
195 Vesiclepedia_527 23660474 Homo sapiens Heterogeneity in neutrophil microparticles reveals distinct proteome and functional properties. Neutrophils Protein - Microparticles
196 Vesiclepedia_37 10878338 Homo sapiens Direct immunosuppressive effects of EBV-encoded latent membrane protein 1. B cells Protein Differential centrifugation Exosomes
197 Vesiclepedia_464 22909304 Pseudomonas aeruginosa Identification of proteins associated with the Pseudomonas aeruginosa biofilm extracellular matrix. Pseudomonas aeruginosa Protein - Membrane vesicles
198 Vesiclepedia_396 19413345 Homo sapiens Proteomic analysis of malignant B-cell derived microparticles reveals CD148 as a potentially useful antigenic biomarker for mantle cell lymphoma diagnosis. B cells Protein - Microparticles
199 Vesiclepedia_626 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Ovarian cancer cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
200 Vesiclepedia_58 17700640 Homo sapiens CD24 is a marker of exosomes secreted into urine and amniotic fluid. Amniotic fluid Protein Differential centrifugation
Sucrose density gradient
Exosomes
201 Vesiclepedia_42 15908444 Homo sapiens Exosomal-like vesicles are present in human blood plasma. Bone marrow cells Protein Differential centrifugation
Filtration
Sucrose density gradient
Exosomes
202 Vesiclepedia_118 21362503 Homo sapiens Protein profile of exosomes from trabecular meshwork cells. Tabecular meshwork cells Protein Differential centrifugation
Sucrose density gradient
Exosomes
203 Vesiclepedia_181 20668554 Homo sapiens Microvesicles derived from adult human bone marrow and tissue specific mesenchymal stem cells shuttle selected pattern of miRNAs Mesenchymal stem cells Protein
miRNA
Differential centrifugation
Ultracentrifugation
Microvesicles
204 Vesiclepedia_235 10648405 Homo sapiens Cellular origin and procoagulant properties of microparticles in meningococcal sepsis Plasma Protein Differential centrifugation
FACS
Microparticles
205 Vesiclepedia_431 21595033 Homo sapiens Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy. Urine Protein - Exosomes
206 Vesiclepedia_318 19483673 Homo sapiens Y-box protein-1 is actively secreted through a non-classical pathway and acts as an extracellular mitogen Monocytes Protein Differential centrifugation
Filtration
Microvesicles
207 Vesiclepedia_68 19619303 Homo sapiens Claudin-containing exosomes in the peripheral circulation of women with ovarian cancer. Plasma Protein Differential centrifugation Exosomes
208 Vesiclepedia_210 21368175 Homo sapiens Cancer cell-derived microvesicles induce transformation by transferring tissue transglutaminase and fibronectin to recipient cells Breast cancer cells Protein Differential centrifugation
Filtration
Microvesicles
209 Vesiclepedia_199 21609964 Homo sapiens Characterization of extracellular circulating microRNA Plasma Protein Differential centrifugation
Filtration
Exosomes
210 Vesiclepedia_575 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Breast cancer cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
211 Vesiclepedia_283 19234131 Homo sapiens Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR Colorectal cancer cells Protein Differential centrifugation Microvesicles
212 Vesiclepedia_65 19415654 Homo sapiens Proteomics of MUC1-containing lipid rafts from plasma membranes and exosomes of human breast carcinoma cells MCF-7. Breast cancer cells Protein Differential centrifugation
Sucrose density gradient
Exosomes
213 Vesiclepedia_444 22418980 Homo sapiens A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes. Urine Protein - Exosomes
214 Vesiclepedia_443 22329422 Homo sapiens Quantitative proteome profiling of normal human circulating microparticles. Plasma Protein - Microparticles
215 Vesiclepedia_433 22014850 Rattus norvegicus Proteomics of microparticles after experimental pulmonary embolism. Plasma Protein - Microparticles
216 Vesiclepedia_591 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Colon cancer cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
217 Vesiclepedia_6 11306949 Mus musculus Nonspecific B and T cell-stimulatory activity mediated by mast cells is associated with exosomes. Mast cells Protein - Exosomes
218 Vesiclepedia_157 21630462 Homo sapiens Proteomic analysis of microvesicles derived from human colorectal cancer ascites Ascites Protein Differential centrifugation
Sucrose density gradient
OptiPrep density gradient
Microvesicles
219 Vesiclepedia_389 18819103 Homo sapiens Structural heterogeneity and protein composition of exosome-like vesicles (prostasomes) in human semen. Seminal fluid Protein - Exosomes/Prostasomes
220 Vesiclepedia_64 18520029 Homo sapiens Exosome-like vesicles with dipeptidyl peptidase IV in human saliva. Saliva Protein Filtration
Diafiltration
Gel filtration
Exosomes
221 Vesiclepedia_94 21828046 Rattus norvegicus The proteo-lipidic composition of exosomes changes during reticulocyte maturation. Reticulocytes Protein
Lipids
Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Exosomes
222 Vesiclepedia_203 19011622 Homo sapiens Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers Glioblastoma cells Protein
miRNA
mRNA
Differential centrifugation
Ultracentrifugation
Filtration
Microvesicles
223 Vesiclepedia_219 10694520 Homo sapiens Elevated levels of shed membrane microparticles with procoagulant potential in the peripheral circulating blood of patients with acute coronary syndromes Plasma Protein Immunoaffinity [Annexin-V] Microparticles
224 Vesiclepedia_163 21901833 Drosophila melanogaster Proteomics analyses of microvesicles released by Drosophila Kc167 and S2 cells Hematocytes Protein Differential centrifugation
Sucrose density gradient
Ultracentrifugation
Microvesicles
225 Vesiclepedia_44 19028452 Homo sapiens Proteomic profiling of human plasma exosomes identifies PPARgamma as an exosome-associated protein. Plasma Protein Filtration
Size exclusion chromatography
Sucrose density gradient
Exosomes
226 Vesiclepedia_4 11487543 Homo sapiens Intestinal epithelial cells secrete exosome-like vesicles. Epithelial cells Protein Differential centrifugation
Sucrose density gradient
Exosomes
227 Vesiclepedia_545 23983189 Homo sapiens Characterization of Multiple Myeloma Vesicles by Label-Free Relative Quantitation. B cells Protein - Exosomes/Extracellular vesicles/Microvesicles
228 Vesiclepedia_427 21408115 Edwardsiella tarda Outer membrane vesicles as a candidate vaccine against edwardsiellosis. Edwardsiella tarda Protein - Membrane vesicles
229 Vesiclepedia_223 10393703 Homo sapiens In vitro generation of endothelial microparticles and possible prothrombotic activity in patients with lupus anticoagulant Endothelial cells Protein Differential centrifugation
Ultracentrifugation
Microparticles
230 Vesiclepedia_38 15210972 Oryctolagus cuniculus Cells release prions in association with exosomes. Epithelial cells Protein Differential centrifugation
Sucrose density gradient
Exosomes
231 Vesiclepedia_513 23533145 Homo sapiens In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Urine Protein - Exosomes/Microvesicles
232 Vesiclepedia_176 21788507 Homo sapiens Hypoxia triggers a proangiogenic pathway involving cancer cell microvesicles and PAR-2-mediated heparin-binding EGF signaling in endothelial cells Glioblastoma cells Protein Differential centrifugation Microvesicles
233 Vesiclepedia_134 15304316 Rattus norvegicus PLD2 is enriched on exosomes and its activity is correlated to the release of exosomes Basophilic leukemia cells Protein
Lipids
Differential centrifugation Exosomes
234 Vesiclepedia_621 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Melanoma cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
235 Vesiclepedia_630 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Ovarian cancer cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
236 Vesiclepedia_34 19190083 Homo sapiens Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense. Tracheobronchial cells Protein
mRNA
Differential centrifugation
Filtration
Sucrose density gradient
Exosomes
237 Vesiclepedia_15 17486113 Mus musculus
Homo sapiens
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Mast cells Protein
mRNA
miRNA
Filtration
Ultracentrifugation
Sucrose density gradient
Exosomes
238 Vesiclepedia_479 23082778 Homo sapiens Comparative and Targeted Proteomic Analyses of Urinary Microparticles from Bladder Cancer and Hernia Patients. Urine Protein - Exosomes/Membrane vesicles
239 Vesiclepedia_579 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Breast cancer cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
240 Vesiclepedia_489 23260141 Mus musculus Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration. Fibroblasts Protein - Exosomes
241 Vesiclepedia_334 20976003 Homo sapiens Selective release of microRNA species from normal and malignant mammary epithelial cells Breast cancer cells Protein
miRNA
Differential centrifugation
Filtration
Exosomes
242 Vesiclepedia_308 16342139 Homo sapiens Proteomic analysis of malignant lymphocyte membrane microparticles using double ionization coverage optimization B cells Protein Differential centrifugation Microparticles
243 Vesiclepedia_66 19199708 Homo sapiens Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT). Saliva Protein Differential centrifugation Exosomes
244 Vesiclepedia_421 21136987 Helicobacter pylori Proteomic and functional characterization of the outer membrane vesicles from the gastric pathogen Helicobacter pylori. Helicobacter pylori Protein - Membrane vesicles
245 Vesiclepedia_406 19806257 Homo sapiens Proteomic and functional characterisation of platelet microparticle size classes. Platelets Protein - Microparticles
246 Vesiclepedia_534 23818640 Homo sapiens Modulation of B-cell exosome proteins by gamma herpesvirus infection. B cells Protein - Exosomes/Microvesicles/Oncosomes/Microparticles
247 Vesiclepedia_214 21364924 Homo sapiens Thermal- and oxidative stress causes enhanced release of NKG2D ligand-bearing immunosuppressive exosomes in leukemia/lymphoma T and B cells T cells Protein Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Exosomes
248 Vesiclepedia_483 23214914 Trypanosoma cruzi Proteomic analysis of Trypanosoma cruzi secretome: characterization of two populations of extracellular vesicles and soluble proteins. Epimastigotes Protein - Exosomes/Extracellular vesicles/Ectosomes
249 Vesiclepedia_247 15741221 Homo sapiens Tissue-factor-bearing microvesicles arise from lipid rafts and fuse with activated platelets to initiate coagulation Plasma Protein Differential centrifugation
Immunobeads (TF)
Microvesicles
250 Vesiclepedia_419 21136642 Mus musculus Oligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons? Oligodendrocytes Protein - Exosomes
251 Vesiclepedia_32 18452139 Homo sapiens Primary human keratinocytes externalize stratifin protein via exosomes. Keratinocytes Protein Differential centrifugation
Sucrose density gradient
Diafiltration
Exosomes
252 Vesiclepedia_576 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Breast cancer cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
253 Vesiclepedia_284 12796750 Homo sapiens High levels of circulating endothelial microparticles in patients with acute coronary syndromes Plasma Protein Differential centrifugation
FACS
Microparticles
254 Vesiclepedia_218 10694520 Homo sapiens Elevated levels of shed membrane microparticles with procoagulant potential in the peripheral circulating blood of patients with acute coronary syndromes Plasma Protein Immunoaffinity [Annexin-V] Microparticles
255 Vesiclepedia_212 21372807 Rattus norvegicus Upregulation of lipid synthesis in small rat adipocytes by microvesicle-associated CD73 from large adipocytes Adipocytes Protein Differential centrifugation Microvesicles
256 Vesiclepedia_169 21859146 Homo sapiens Identification of a conserved glycan signature for microvesicles T cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Microvesicles
257 Vesiclepedia_135 2777884 Cavia porcellus Asymmetric Distribution of Phospholipids in the Membrane of Vesicles Released During In Vitro Maturation of Guinea Pig Reticulocytes: Evidence Precluding a Role for "Aminophospholipid Translocase Reticulocytes Proteins
Lipids
Differential centrifugation
Ultracentrifugation
Exosomes
258 Vesiclepedia_414 20559436 Saccharomyces cerevisiae Characterization of yeast extracellular vesicles: evidence for the participation of different pathways of cellular traffic in vesicle biogenesis. Saccharomyces cerevisiae Protein - Extracellular vesicles
259 Vesiclepedia_250 9396452 Homo sapiens Cell-derived microparticles generated in patients during cardiopulmonary bypass are highly procoagulant Plasma Protein
Lipids
Differential centrifugation Microparticles
260 Vesiclepedia_387 18563738 Homo sapiens Comparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles. Endothelial cells Protein - Microparticles
261 Vesiclepedia_105 21763319 Homo sapiens Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells. Pancreatic adenocarcinoma cells Protein Differential centrifugation
Filtration
Ultrafiltration
Ultracentrifugation
Exosomes
262 Vesiclepedia_316 18472965 Homo sapiens Cathepsin B mediates the pH-dependent proinvasive activity of tumor-shed microvesicles Ovarian cancer cells Protein Differential centrifugation Microvesicles
263 Vesiclepedia_412 20156641 Homo sapiens Proteomics of microparticles after deep venous thrombosis. Plasma Protein - Membrane vesicles/Microparticles
264 Vesiclepedia_168 21859146 Homo sapiens Identification of a conserved glycan signature for microvesicles T cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Microvesicles
265 Vesiclepedia_52 14975938 Homo sapiens Proteomic analysis of exosomes isolated from human malignant pleural effusions. Malignant pleural effusions Protein Differential centrifugation
Sucrose density gradient
Exosomes
266 Vesiclepedia_99 21828046 Rattus norvegicus The proteo-lipidic composition of exosomes changes during reticulocyte maturation. Reticulocytes Protein
Lipids
Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Exosomes
267 Vesiclepedia_371 16456881 Neisseria meningitidis Outer membrane vesicles from group B Neisseria meningitidis delta gna33 mutant: proteomic and immunological comparison with detergent-derived outer membrane vesicles. Neisseria meningitidis Protein - Membrane vesicles
268 Vesiclepedia_89 20424270 Rattus norvegicus Exosomes account for vesicle-mediated transcellular transport of activatable phospholipases and prostaglandins. Basophilic leukemia cells Protein
Lipids
Differential centrifugation
Sucrose density gradient
Exosomes
269 Vesiclepedia_112 21601258 Homo sapiens Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage. Serum Protein
miRNA
Differential centrifugation
Sucrose density gradient
Exosomes
270 Vesiclepedia_393 19369228 Homo sapiens Proteomic analysis reveals presence of platelet microparticles in endothelial progenitor cell cultures. Endothelial cells Protein - Microparticles
271 Vesiclepedia_116 21505438 Homo sapiens Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells. B cells Protein
miRNA
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
272 Vesiclepedia_21 19837982 Homo sapiens Proteomic and bioinformatic analysis of immunoaffinity-purified exosomes derived from the human colon tumor cell line LIM1215. Colorectal cancer cells Protein Filtration
Ultracentrifugation
Sucrose density gradient
Exosomes
273 Vesiclepedia_113 21557262 Homo sapiens Proteomic identification of exosomal LRG1: A potential urinary biomarker for detecting NSCLC. Urine Protein Differential centrifugation
Ultracentrifugation
Exosomes
274 Vesiclepedia_307 16342139 Homo sapiens Proteomic analysis of malignant lymphocyte membrane microparticles using double ionization coverage optimization T cells Protein Differential centrifugation Microparticles
275 Vesiclepedia_299 12796750 Homo sapiens High levels of circulating endothelial microparticles in patients with acute coronary syndromes Plasma Protein Differential centrifugation
FACS
Microparticles
276 Vesiclepedia_525 23658846 Mus musculus Immunomodulatory impact of leishmania-induced macrophage exosomes: a comparative proteomic and functional analysis. Macrophages Protein - Exosomes
277 Vesiclepedia_537 23818640 Homo sapiens Modulation of B-cell exosome proteins by gamma herpesvirus infection. B cells Protein - Exosomes/Microvesicles/Oncosomes/Microparticles
278 Vesiclepedia_314 15499615 Homo sapiens Microvesicles derived from activated platelets induce metastasis and angiogenesis in lung cancer Lung cancer cells Protein Differential centrifugation
FACS
Microvesicles
279 Vesiclepedia_229 2942561 Homo sapiens Platelet surface glycoproteins. Studies on resting and activated platelets and platelet membrane microparticles in normal subjects, and observations in patients during adult respiratory distress syndrome and cardiac surgery Plasma Protein Differential centrifugation Microparticles
280 Vesiclepedia_420 21136987 Helicobacter pylori Proteomic and functional characterization of the outer membrane vesicles from the gastric pathogen Helicobacter pylori. Helicobacter pylori Protein - Membrane vesicles
281 Vesiclepedia_28 19109410 Homo sapiens Proteomic and immunologic analyses of brain tumor exosomes. Glioma cells Protein Differential centrifugation
Sucrose density gradient
Exosomes
282 Vesiclepedia_90 21828046 Rattus norvegicus The proteo-lipidic composition of exosomes changes during reticulocyte maturation. Reticulocytes Protein
Lipids
Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Exosomes
283 Vesiclepedia_354 24115447 Homo sapiens Comparative proteomics evaluation of plasma exosome isolation techniques and assessment of the stability of exosomes in normal human blood plasma Plasma Protein Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Exosomes
284 Vesiclepedia_413 20535238 Rattus norvegicus Candidate biomarkers in exosome-like vesicles purified from rat and mouse urine samples. Urine Protein - Exosomes
285 Vesiclepedia_143 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells Protein Sucrose density gradient Exosomes
286 Vesiclepedia_323 20304794 Homo sapiens Functional delivery of viral miRNAs via exosomes B cells Protein Differential centrifugation Exosomes
287 Vesiclepedia_177 19567368 Homo sapiens Proteomics characterization of cell membrane blebs in human retinal pigment epithelium cells Epithelial cells Protein Differential centrifugation Membrane blebs
288 Vesiclepedia_35 19367702 Rattus norvegicus Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes. Hepatocytes Protein Differential centrifugation
Filtration
Sucrose density gradient
Exosomes
289 Vesiclepedia_93 20124479 Rattus norvegicus Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation. Pancreatic adenocarcinoma cells Protein
mRNA
Differential centrifugation
Sucrose density gradient
Exosomes
290 Vesiclepedia_110 21601258 Homo sapiens Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage. Ascites Protein
miRNA
Differential centrifugation
Sucrose density gradient
Exosomes
291 Vesiclepedia_248 15741221 Homo sapiens Tissue-factor-bearing microvesicles arise from lipid rafts and fuse with activated platelets to initiate coagulation Monocytic leukemia cells Protein Differential centrifugation Microvesicles
292 Vesiclepedia_251 9396452 Homo sapiens Cell-derived microparticles generated in patients during cardiopulmonary bypass are highly procoagulant Plasma Protein
Lipids
Differential centrifugation Microparticles
293 Vesiclepedia_136 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells Protein Sucrose density gradient Exosomes
294 Vesiclepedia_625 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Melanoma cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
295 Vesiclepedia_268 12757771 Homo sapiens Endothelial cells release phenotypically and quantitatively distinct microparticles in activation and apoptosis Endothelial cells Protein Differential centrifugation
FACS
Microparticles
296 Vesiclepedia_228 2942561 Homo sapiens Platelet surface glycoproteins. Studies on resting and activated platelets and platelet membrane microparticles in normal subjects, and observations in patients during adult respiratory distress syndrome and cardiac surgery Serum Protein Differential centrifugation Microparticles
297 Vesiclepedia_146 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells Protein Sucrose density gradient Exosomes
298 Vesiclepedia_584 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Brain cancer cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
299 Vesiclepedia_122 21235781 Homo sapiens Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages. Saliva Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
300 Vesiclepedia_75 19381331 Homo sapiens High levels of exosomes expressing CD63 and caveolin-1 in plasma of melanoma patients. Plasma Protein Differential centrifugation Exosomes
301 Vesiclepedia_12 15478216 Homo sapiens Proteomic analysis of melanoma-derived exosomes by two-dimensional polyacrylamide gel electrophoresis and mass spectrometry. Melanoma cells Protein Filtration
Ultracentrifugation
Sucrose density gradient
Exosomes
302 Vesiclepedia_391 19327352 Bos taurus Anchorage-independent growth of breast carcinoma cells is mediated by serum exosomes. Serum Protein - Exosomes
303 Vesiclepedia_221 9918520 Homo sapiens Shed membrane microparticles with procoagulant potential in human atherosclerotic plaques: a role for apoptosis in plaque thrombogenicity Atherosclerotic plaques Protein
Lipids
Differential centrifugation
Immunoaffinity [Annexin-V]
Apoptotic bodies
304 Vesiclepedia_309 17536014 Homo sapiens Endothelial progenitor cell derived microvesicles activate an angiogenic program in endothelial cells by a horizontal transfer of Mrna Endothelial cells Protein
mRNA
Differential centrifugation
Ultracentrifugation
FACS
Microvesicles
305 Vesiclepedia_202 21601655 Homo sapiens Sizing and phenotyping of cellular vesicles using Nanoparticle Tracking Analysis Placenta Protein Differential centrifugation
Ultracentrifugation
Microvesicles
306 Vesiclepedia_154 21966536 Mus musculus Leukocyte- and platelet-derived microvesicle interactions following in vitro and in vivo activation of toll-like receptor 4 by lipopolysaccharide Plasma Protein Differential centrifugation
Filtration
Microvesicles
307 Vesiclepedia_573 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells Protein Differential centrifugation
Ultracenrifugation
Immunobeads (CD81 FT)
Extracellular vesicle
308 Vesiclepedia_565 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells Protein Differential centrifugation
Ultracenrifugation
OptiPrep density gradient
Exosomes
309 Vesiclepedia_266 18425114 Mus musculus Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells Plasma Protein Differential centrifugation
Ultracentrifugation
Microvesicles
310 Vesiclepedia_398 19530224 Homo sapiens Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes. Keratinocytes Protein - Exosomes
311 Vesiclepedia_566 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells Protein Differential centrifugation
Ultracenrifugation
Immunobeads (Igg1 PD)
Extracellular vesicle
312 Vesiclepedia_70 19812188 Rattus norvegicus Immature dendritic cell-derived exosomes rescue septic animals via milk fat globule epidermal growth factor VIII. Dendritic cells Protein Differential centrifugation Exosomes
313 Vesiclepedia_26 19109410 Mus musculus Proteomic and immunologic analyses of brain tumor exosomes. Brain tumor Protein Differential centrifugation
Sucrose density gradient
Exosomes
314 Vesiclepedia_226 12514112 Homo sapiens Intravascular tissue factor initiates coagulation via circulating microvesicles and platelets Platelets Protein Differential centrifugation Microvesicles
315 Vesiclepedia_167 21859146 Homo sapiens Identification of a conserved glycan signature for microvesicles T cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Microvesicles
316 Vesiclepedia_222 12514112 Homo sapiens Intravascular tissue factor initiates coagulation via circulating microvesicles and platelets Plasma Protein Differential centrifugation
FACS
Microvesicles
317 Vesiclepedia_600 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Kidney cancer cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
318 Vesiclepedia_97 21828046 Rattus norvegicus The proteo-lipidic composition of exosomes changes during reticulocyte maturation. Reticulocytes Protein
Lipids
Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Exosomes
319 Vesiclepedia_151 22075275 Homo sapiens Methodology for isolation, identification and characterization of microvesicles in peripheral blood Plasma Protein Differential centrifugation
Filtration
Ultracentrifugation
Microvesicles
320 Vesiclepedia_562 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells Protein Differential centrifugation
Ultracenrifugation
OptiPrep density gradient
Microvesicles
321 Vesiclepedia_302 1321158 Rattus norvegicus Membrane anchoring of the autoantigen GAD65 to microvesicles in pancreatic beta-cells by palmitoylation in the NH2-terminal domain. Pancreatic cells Protein Differential centrifugation Microvesicles
322 Vesiclepedia_613 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Lung cancer cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
323 Vesiclepedia_19 16302729 Homo sapiens Purification, characterization and biological significance of tumor-derived exosomes. Breast cancer cells Protein Differential centrifugation
Sucrose density gradient
Filtration
Immunobeads(HER2)
Exosomes
324 Vesiclepedia_137 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells Protein Sucrose density gradient Exosomes
325 Vesiclepedia_142 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells Protein Sucrose density gradient Exosomes
326 Vesiclepedia_230 2294986 Homo sapiens Direct detection of activated platelets and platelet-derived microparticles in humans Plasma Protein FACS Microparticles
327 Vesiclepedia_409 20031610 Homo sapiens Proteomics, metabolomics, and immunomics on microparticles derived from human atherosclerotic plaques. Carotid atherosclerotic plaques Protein - Microparticles
328 Vesiclepedia_160 21630462 Homo sapiens Proteomic analysis of microvesicles derived from human colorectal cancer ascites Ascites Protein Differential centrifugation
Sucrose density gradient
OptiPrep density gradient
Microvesicles
329 Vesiclepedia_628 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Ovarian cancer cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
330 Vesiclepedia_2 3597417 Ovis aries Vesicle formation during reticulocyte maturation. Association of plasma membrane activities with released vesicles (exosomes). Reticulocytes Protein
Lipids
Differential centrifugation Exosomes
331 Vesiclepedia_482 23161513 Homo sapiens Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS. Colorectal cancer cells Protein - Exosomes
332 Vesiclepedia_262 12805058 Homo sapiens Sickle blood contains tissue factor-positive microparticles derived from endothelial cells and monocytes Plasma Protein
Lipids
Differential centrifugation
Ultracentrifugation
FACS
Microparticles
333 Vesiclepedia_216 21293856 Homo sapiens Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC Breast cancer cells Protein Differential centrifugation
Filtration
Ultrafiltration
Ultracentrifugation
Sucrose density gradient
Exosomes
334 Vesiclepedia_618 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Melanoma cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
335 Vesiclepedia_574 27601599 Homo sapiens Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components Breast milk Protein Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Extracellular vesicles
336 Vesiclepedia_254 9126269 Homo sapiens Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations T4-lymphoblastoid cells Protein Differential centrifugation
Sucrose density gradient
Microvesicles
337 Vesiclepedia_238 21293856 Homo sapiens Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC Ascites Protein Differential centrifugation
Filtration
Ultrafiltration
Ultracentrifugation
Sucrose density gradient
Exosomes
338 Vesiclepedia_627 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Ovarian cancer cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
339 Vesiclepedia_140 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells Protein Sucrose density gradient Exosomes
340 Vesiclepedia_263 12805058 Homo sapiens Sickle blood contains tissue factor-positive microparticles derived from endothelial cells and monocytes Plasma Protein Differential centrifugation
Ultracentrifugation
FACS
Microparticles
341 Vesiclepedia_411 20124223 Homo sapiens Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes. Squamous carcinoma cells Protein - Exosomes
342 Vesiclepedia_45 18589210 Homo sapiens MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer. Serum Protein
miRNA
Ultracentrifugation
Immunobeads (EpCAM)
Exosomes
343 Vesiclepedia_375 18095356 Gallus gallus Proteome analysis of matrix vesicles isolated from femurs of chicken embryo. 17-day-old embryo leg bone Protein - Matrix vesicles
344 Vesiclepedia_519 23585444 Homo sapiens Identification and characterization of proteins isolated from microvesicles derived from human lung cancer pleural effusions. Malignant pleural effusions Protein - Exosomes/Microvesicles/Ectosomes/Microparticles
345 Vesiclepedia_126 - Homo sapiens Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy? Mesenchymal stem cells Protein HPLC Exosomes
346 Vesiclepedia_225 10393703 Homo sapiens In vitro generation of endothelial microparticles and possible prothrombotic activity in patients with lupus anticoagulant Plasma Protein Differential centrifugation Microparticles
347 Vesiclepedia_303 19930720 Homo sapiens Colorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells Colorectal cancer cells Protein
mRNA
Differential centrifugation
Ultrafiltration
Optiprep density gradient
Microvesicles
348 Vesiclepedia_304 17478559 Mus musculus Identification and characterization of microvesicles secreted by 3T3-L1 adipocytes: redox- and hormone-dependent induction of milk fat globule-epidermal growth 8-associated microvesicles Adipocytes Protein Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Microvesicles
349 Vesiclepedia_556 24069378 Homo sapiens Proteome profiling of neuroblastoma-derived exosomes reveal the expression of proteins potentially involved in tumor progression. Neuroblastoma cells Protein - Exosomes/Membrane vesicles
350 Vesiclepedia_29 19109410 Homo sapiens Proteomic and immunologic analyses of brain tumor exosomes. Serum Protein Differential centrifugation
Sucrose density gradient
Exosomes
351 Vesiclepedia_593 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Colon cancer cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
352 Vesiclepedia_315 15499615 Homo sapiens Microvesicles derived from activated platelets induce metastasis and angiogenesis in lung cancer Lung cancer cells Protein Differential centrifugation
FACS
Microvesicles
353 Vesiclepedia_374 18039940 Cryptococcus neoformans Extracellular vesicles produced by Cryptococcus neoformans contain protein components associated with virulence. Cryptococcus neoformans Protein - Exosomes/Extracellular vesicles
354 Vesiclepedia_77 20224111 Homo sapiens Proteomics analysis of bladder cancer exosomes. Urine Protein Differential centrifugation
Sucrose density gradient
Exosomes
355 Vesiclepedia_397 19413345 Homo sapiens Proteomic analysis of malignant B-cell derived microparticles reveals CD148 as a potentially useful antigenic biomarker for mantle cell lymphoma diagnosis. B cells Protein - Microparticles
356 Vesiclepedia_111 21601258 Homo sapiens Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage. Serum Protein
miRNA
Differential centrifugation
Sucrose density gradient
Immunobeads (CD24)
Exosomes
357 Vesiclepedia_279 16192427 Homo sapiens Circulating endothelial microparticles are associated with vascular dysfunction in patients with end-stage renal failure Plasma Protein Differential centrifugation
FACS
Microparticles
358 Vesiclepedia_324 20079801 Mus musculus Microvesicle entry into marrow cells mediates tissue-specific changes in mRNA by direct delivery of mRNA and induction of transcription Lung cells Protein
miRNA
Differential centrifugation
FACS
Microvesicles
359 Vesiclepedia_10 11390481 Mus musculus Proteomic analysis of dendritic cell-derived exosomes: a secreted subcellular compartment distinct from apoptotic vesicles. Dendritic cells Protein Differential centrifugation
Sucrose density gradient
Exosomes
360 Vesiclepedia_348 22285593 Homo sapiens Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes. Colorectal cancer cells Protein Differential centrifugation
Filtration
Immunobeads (EpCAM)
Ultracentrifugation
Exosomes
361 Vesiclepedia_467 23000592 Homo sapiens In-depth analysis of the secretome identifies three major independent secretory pathways in differentiating human myoblasts. Neonatal myoblast cells Protein - Microvesicles/Nanovesicles
362 Vesiclepedia_213 21372807 Rattus norvegicus Upregulation of lipid synthesis in small rat adipocytes by microvesicle-associated CD73 from large adipocytes Adipocytes Protein Differential centrifugation Microvesicles
363 Vesiclepedia_13 15326289 Homo sapiens Identification and proteomic profiling of exosomes in human urine. Urine Protein Ultracentrifugation Exosomes
364 Vesiclepedia_571 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells Protein Differential centrifugation
Ultracenrifugation
Immunobeads (CD63 FT)
Extracellular vesicle
365 Vesiclepedia_257 9126269 Homo sapiens Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations T lymphoblastic leukemia Protein Differential centrifugation
Sucrose density gradient
Microvesicles
366 Vesiclepedia_583 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Brain cancer cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
367 Vesiclepedia_292 10415024 Homo sapiens Activated human T cells release bioactive Fas ligand and APO2 ligand in microvesicles T cells Protein Differential centrifugation
Ultracentrifugation
FACS
Microvesicles
368 Vesiclepedia_48 17641064 Homo sapiens Exosomes with immune modulatory features are present in human breast milk. Breast milk Protein Differential centrifugation
Filtration
Sucrose density gradient
Exosomes
369 Vesiclepedia_388 18570454 Homo sapiens Proteomic analysis of exosomes from human neural stem cells by flow field-flow fractionation and nanoflow liquid chromatography-tandem mass spectrometry. Neural stem cells Protein - Exosomes/Membrane vesicles
370 Vesiclepedia_400 19548894 Acinetobacter baumannii Proteome analysis of outer membrane vesicles from a clinical Acinetobacter baumannii isolate. Acinetobacter baumannii Protein - Membrane vesicles
371 Vesiclepedia_540 23886663 Homo sapiens LRRK2 Secretion in Exosomes is Regulated by 14-3-3. Urine Protein - Exosomes/Microvesicles
372 Vesiclepedia_453 22635005 Homo sapiens Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. Melanoma cells Protein - Exosomes
373 Vesiclepedia_196 21668449 Mus musculus SV31 is a Zn2+-binding synaptic vesicle protein PC12 cells Protein Differential centrifugation
Sucrose density gradient
Large dense core vesicles
374 Vesiclepedia_57 17700640 Homo sapiens CD24 is a marker of exosomes secreted into urine and amniotic fluid. Urine Protein Differential centrifugation
Sucrose density gradient
Exosomes
375 Vesiclepedia_587 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Colon cancer cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
376 Vesiclepedia_448 22448133 Pseudomonas aeruginosa Vesiculation from Pseudomonas aeruginosa under SOS. Pseudomonas aeruginosa Protein - Membrane vesicles
377 Vesiclepedia_508 23511837 Homo sapiens Differential protein profiling of renal cell carcinoma urinary exosomes. Urine Protein - Exosomes/Nanovesicles
378 Vesiclepedia_520 23601281 Homo sapiens Proteomic characterization of human platelet-derived microparticles. Blood Protein - Microparticles
379 Vesiclepedia_162 21901833 Drosophila melanogaster Proteomics analyses of microvesicles released by Drosophila Kc167 and S2 cells Hematocytes Protein
PTM Ubiquitination
Differential centrifugation
Sucrose density gradient
Ultracentrifugation
Microvesicles
380 Vesiclepedia_472 23043909 Pseudomonas syringae Virulence factors are released in association with outer membrane vesicles of Pseudomonas syringae pv. tomato T1 during normal growth. Pseudomonas syringae Protein - Membrane vesicles
381 Vesiclepedia_95 21828046 Rattus norvegicus The proteo-lipidic composition of exosomes changes during reticulocyte maturation. Reticulocytes Protein
Lipids
Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Exosomes
382 Vesiclepedia_546 23983189 Homo sapiens Characterization of Multiple Myeloma Vesicles by Label-Free Relative Quantitation. B cells Protein - Exosomes/Extracellular vesicles/Microvesicles
383 Vesiclepedia_264 18425114 Homo sapiens Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells Epidermoid carcinoma cells Protein Differential centrifugation
Ultracentrifugation
Microvesicles
384 Vesiclepedia_67 19619303 Homo sapiens Claudin-containing exosomes in the peripheral circulation of women with ovarian cancer. Ovarian cancer cells Protein Differential centrifugation
Sucrose density gradient
Exosomes
385 Vesiclepedia_349 22285593 Homo sapiens Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes. Colorectal cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Exosomes
386 Vesiclepedia_491 23264574 Francisella novicida Production of Outer Membrane Vesicles and Outer Membrane Tubes by Francisella novicida. Francisella novicida Protein - Membrane vesicles
387 Vesiclepedia_536 23818640 Homo sapiens Modulation of B-cell exosome proteins by gamma herpesvirus infection. B cells Protein - Exosomes/Microvesicles/Oncosomes/Microparticles
388 Vesiclepedia_101 21828046 Rattus norvegicus The proteo-lipidic composition of exosomes changes during reticulocyte maturation. Reticulocytes Protein
Lipids
Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Exosomes
389 Vesiclepedia_123 21235781 Homo sapiens Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages. Plasma Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
390 Vesiclepedia_478 23082778 Homo sapiens Comparative and Targeted Proteomic Analyses of Urinary Microparticles from Bladder Cancer and Hernia Patients. Urine Protein - Exosomes/Membrane vesicles
391 Vesiclepedia_217 21293856 Homo sapiens Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC Serum Protein Differential centrifugation
Filtration
Ultrafiltration
Ultracentrifugation
Sucrose density gradient
Exosomes
392 Vesiclepedia_133 19188015 Homo sapiens Systemic presence and tumor-growth promoting effect of ovarian carcinoma released exosomes Ovarian cancer cells Protein
Lipids
Differential centrifugation
Sucrose density gradient
Exosomes
393 Vesiclepedia_488 23230278 Homo sapiens Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids. Colorectal cancer cells Protein - Exosomes/Extracellular vesicles/Microvesicles
394 Vesiclepedia_220 10694520 Homo sapiens Elevated levels of shed membrane microparticles with procoagulant potential in the peripheral circulating blood of patients with acute coronary syndromes Plasma Protein Immunoaffinity [Annexin-V] Microparticles
395 Vesiclepedia_132 19188015 Homo sapiens Systemic presence and tumor-growth promoting effect of ovarian carcinoma released exosomes Ovarian cancer cells Protein
Lipids
Differential centrifugation
Sucrose density gradient
Exosomes
396 Vesiclepedia_170 21859146 Homo sapiens Identification of a conserved glycan signature for microvesicles Colorectal cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Microvesicles
397 Vesiclepedia_559 26098775 Citrus Limon L. Citrus limon-derived nanovesicles inhibit cancer cell proliferation and suppress CML xenograft growth by inducing TRAIL-mediated cell death Lemon juice Protein Differential centrifugation
Ultracenrifugation
Nanovesicles
398 Vesiclepedia_5 11145662 Mus musculus Mast cell-dependent B and T lymphocyte activation is mediated by the secretion of immunologically active exosomes. Mast cells Protein Differential centrifugation Exosomes
399 Vesiclepedia_8 12626558 Mus musculus Mast cell-derived exosomes induce phenotypic and functional maturation of dendritic cells and elicit specific immune responses in vivo. B cells Protein Differential centrifugation Exosomes
400 Vesiclepedia_59 17700640 Mus musculus CD24 is a marker of exosomes secreted into urine and amniotic fluid. Amniotic fluid Protein Differential centrifugation
Sucrose density gradient
Exosomes
401 Vesiclepedia_139 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells Protein Sucrose density gradient Exosomes
402 Vesiclepedia_355 24115447 Homo sapiens Comparative proteomics evaluation of plasma exosome isolation techniques and assessment of the stability of exosomes in normal human blood plasma Plasma Protein Differential centrifugation
Filtration
Ultracentrifugation
Immunobeads (EpCAM)
Exosomes
403 Vesiclepedia_287 12417540 Homo sapiens Elevated numbers of tissue-factor exposing microparticles correlate with components of the metabolic syndrome in uncomplicated type 2 diabetes mellitus Plasma Protein Differential centrifugation
FACS
Microparticles
404 Vesiclepedia_125 21059916 Homo sapiens Human tumor virus utilizes exosomes for intercellular communication. Nasopharyngeal carcinoma cells Protein Differential centrifugation Exosomes
405 Vesiclepedia_609 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Lung cancer cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
406 Vesiclepedia_141 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells Protein Sucrose density gradient Exosomes
407 Vesiclepedia_185 22116803 Equus caballus Cell-Secreted Vesicles in Equine Ovarian Follicular Fluid Contain miRNAs and Proteins: A Possible New Form of Cell Communication Within the Ovarian Follicle Follicular fluid Protein
miRNA
Differential centrifugation
Exoquick
Exosomes
408 Vesiclepedia_461 22848702 Homo sapiens Medulloblastoma exosome proteomics yield functional roles for extracellular vesicles. Medulloblastoma cells Protein - Exosomes/Membrane vesicles/Extracellular vesicles
409 Vesiclepedia_507 23511837 Homo sapiens Differential protein profiling of renal cell carcinoma urinary exosomes. Urine Protein - Exosomes/Nanovesicles
410 Vesiclepedia_197 21616097 Homo sapiens Release of podocalyxin into the extracellular space. Role of metalloproteinases Testicular cancer cells Protein Differential centrifugation Microvesicles
411 Vesiclepedia_16 9685355 Homo sapiens Selective enrichment of tetraspan proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B-lymphocytes. B cells Protein Differential centrifugation
Sucrose density gradient
Exosomes
412 Vesiclepedia_596 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Kidney cancer cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
413 Vesiclepedia_298 12796750 Homo sapiens High levels of circulating endothelial microparticles in patients with acute coronary syndromes Plasma Protein Differential centrifugation
FACS
Microparticles
414 Vesiclepedia_120 21362503 Homo sapiens Protein profile of exosomes from trabecular meshwork cells. Aqueous humor Protein Differential centrifugation
Sucrose density gradient
Exosomes
415 Vesiclepedia_492 23333927 Homo sapiens Characterization and proteomic analysis of ovarian cancer-derived exosomes. Ovarian cancer cells Protein - Exosomes
416 Vesiclepedia_104 21763319 Homo sapiens Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells. Pancreatic adenocarcinoma cells Protein Differential centrifugation
Filtration
Ultrafiltration
Ultracentrifugation
Exosomes
417 Vesiclepedia_614 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Lung cancer cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
418 Vesiclepedia_347 22285593 Homo sapiens Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes. Colorectal cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
419 Vesiclepedia_269 12757771 Homo sapiens Endothelial cells release phenotypically and quantitatively distinct microparticles in activation and apoptosis Endothelial cells Protein Differential centrifugation
FACS
Microparticles
420 Vesiclepedia_404 19548909 Homo sapiens Differential stimulation of monocytic cells results in distinct populations of microparticles. Monocytes Protein - Microparticles
421 Vesiclepedia_227 2942561 Homo sapiens Platelet surface glycoproteins. Studies on resting and activated platelets and platelet membrane microparticles in normal subjects, and observations in patients during adult respiratory distress syndrome and cardiac surgery Plasma Protein Differential centrifugation Microparticles
422 Vesiclepedia_449 22448133 Pseudomonas aeruginosa Vesiculation from Pseudomonas aeruginosa under SOS. Pseudomonas aeruginosa Protein - Membrane vesicles
423 Vesiclepedia_585 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Brain cancer cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
424 Vesiclepedia_9 12626558 Mus musculus Mast cell-derived exosomes induce phenotypic and functional maturation of dendritic cells and elicit specific immune responses in vivo. Macrophages Protein Differential centrifugation Exosomes
425 Vesiclepedia_377 18346024 Homo sapiens The proteome of red cell membranes and vesicles during storage in blood bank conditions. Red blood cells Protein - Microvesicles/Nanovesicles
426 Vesiclepedia_634 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Prostate cancer cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
427 Vesiclepedia_243 22149170 Homo sapiens The Protein Interaction Network of Extracellular Vesicles Derived from Human Colorectal Cancer Cells Colorectal cancer cells Protein Differential centrifugation
Ultrafiltration
Ultracentrifugation
Sucrose density gradient
428 Vesiclepedia_581 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Brain cancer cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
429 Vesiclepedia_498 23376485 Homo sapiens Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. Urine Protein - Exosomes/Membrane vesicles
430 Vesiclepedia_487 23230278 Homo sapiens Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids. Colorectal cancer cells Protein - Exosomes/Extracellular vesicles/Microvesicles
431 Vesiclepedia_517 23585443 Homo sapiens Proteome profiling of exosomes derived from human primary and metastatic colorectal cells reveal differential expression of key metastatic factors and signal transduction components. Colorectal cancer cells Protein - Exosomes/Membrane vesicles
432 Vesiclepedia_282 19234131 Homo sapiens Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR Lung cancer cells Protein Differential centrifugation Microvesicles
433 Vesiclepedia_63 19056867 Homo sapiens Large-scale proteomics and phosphoproteomics of urinary exosomes. Urine Protein Differential centrifugation Exosomes
434 Vesiclepedia_578 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Breast cancer cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
435 Vesiclepedia_103 21763319 Homo sapiens Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells. Pancreatic adenocarcinoma cells Protein Differential centrifugation
Filtration
Ultrafiltration
Ultracentrifugation
Exosomes
436 Vesiclepedia_106 21763319 Homo sapiens Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells. Pancreatic adenocarcinoma cells Protein Differential centrifugation
Filtration
Ultrafiltration
Ultracentrifugation
Exosomes
437 Vesiclepedia_172 21859146 Homo sapiens Identification of a conserved glycan signature for microvesicles Melanoma cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Microvesicles
438 Vesiclepedia_305 17478559 Rattus norvegicus Identification and characterization of microvesicles secreted by 3T3-L1 adipocytes: redox- and hormone-dependent induction of milk fat globule-epidermal growth 8-associated microvesicles Adipocytes Protein Differential centrifugation Microvesicles
439 Vesiclepedia_53 14975938 Homo sapiens Proteomic analysis of exosomes isolated from human malignant pleural effusions. Malignant pleural effusions Protein Differential centrifugation
Sucrose density gradient
Exosomes
440 Vesiclepedia_423 21138299 Francisella tularensis Proteomic characterization and functional analysis of outer membrane vesicles of Francisella novicida suggests possible role in virulence and use as a vaccine. Francisella tularensis Protein - Membrane vesicles
441 Vesiclepedia_47 17641064 Homo sapiens Exosomes with immune modulatory features are present in human breast milk. B cells Protein Differential centrifugation
Filtration
Sucrose density gradient
Exosomes
442 Vesiclepedia_3 10545503 Mus musculus Molecular characterization of dendritic cell-derived exosomes. Selective accumulation of the heat shock protein hsc73. Dendritic cells Protein Differential centrifugation
Sucrose density gradient
Exosomes
443 Vesiclepedia_109 21601258 Homo sapiens Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage. Malignant pleural effusions Protein
miRNA
Differential centrifugation
Sucrose density gradient
Immunobeads (EpCAM)
Exosomes
444 Vesiclepedia_107 21763319 Homo sapiens Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells. Pancreatic adenocarcinoma cells Protein Differential centrifugation
Filtration
Ultrafiltration
Ultracentrifugation
Exosomes
445 Vesiclepedia_276 12021310 Homo sapiens Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles Melanoma cells Protein Differential centrifugation
Ultracentrifugation
Microvesicles
446 Vesiclepedia_569 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells Protein Differential centrifugation
Ultracenrifugation
Immunobeads (CD9 FT)
Extracellular vesicle
447 Vesiclepedia_402 19548909 Homo sapiens Differential stimulation of monocytic cells results in distinct populations of microparticles. Monocytes Protein - Microparticles
448 Vesiclepedia_380 18346024 Homo sapiens The proteome of red cell membranes and vesicles during storage in blood bank conditions. Red blood cells Protein - Microvesicles/Nanovesicles
449 Vesiclepedia_567 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells Protein Differential centrifugation
Ultracenrifugation
Immunobeads (Igg1 FT)
Extracellular vesicle
450 Vesiclepedia_312 15499615 Homo sapiens Microvesicles derived from activated platelets induce metastasis and angiogenesis in lung cancer Lung cancer cells Protein Differential centrifugation
FACS
Microvesicles
451 Vesiclepedia_255 9126269 Homo sapiens Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations Burkitt's lymphoma Protein Differential centrifugation
Sucrose density gradient
Microvesicles
452 Vesiclepedia_612 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Lung cancer cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
453 Vesiclepedia_437 22106071 Homo sapiens Proteomic analysis of urine exosomes by multidimensional protein identification technology (MudPIT). Urine Protein - Exosomes/Membrane vesicles
454 Vesiclepedia_416 20687614 Myxococcus xanthus Profiling the outer membrane proteome during growth and development of the social bacterium Myxococcus xanthus by selective biotinylation and analyses of outer membrane vesicles. Myxococcus xanthus Protein - Membrane vesicles
455 Vesiclepedia_14 16081791 Mus musculus Proteomic analysis of microglia-derived exosomes: metabolic role of the aminopeptidase CD13 in neuropeptide catabolism. Microglia Protein Differential centrifugation
Sucrose density gradient
Exosomes
456 Vesiclepedia_551 24009886 Homo sapiens Cellular stress conditions are reflected in the protein and RNA content of endothelial cell-derived exosomes. Endothelial cells Protein - Exosomes/Extracellular vesicles
457 Vesiclepedia_617 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Melanoma cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
458 Vesiclepedia_490 23264574 Francisella novicida Production of Outer Membrane Vesicles and Outer Membrane Tubes by Francisella novicida. Francisella novicida Protein - Membrane vesicles
459 Vesiclepedia_620 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Melanoma cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
460 Vesiclepedia_30 16446100 Rattus norvegicus Exosomes are released by cultured cortical neurones. Cortical neurones Protein Differential centrifugation
Sucrose density gradient
Exosomes
461 Vesiclepedia_286 12417540 Homo sapiens Elevated numbers of tissue-factor exposing microparticles correlate with components of the metabolic syndrome in uncomplicated type 2 diabetes mellitus Plasma Protein Differential centrifugation
FACS
Microparticles
462 Vesiclepedia_237 21293856 Homo sapiens Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC Melanoma cells Protein Differential centrifugation
Filtration
Ultrafiltration
Ultracentrifugation
Sucrose density gradient
Exosomes
463 Vesiclepedia_445 22418980 Homo sapiens A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes. Urine Protein - Exosomes
464 Vesiclepedia_503 23459212 Bos taurus Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis. Milk Protein - Exosomes
465 Vesiclepedia_244 22148876 Homo sapiens Proteomic analysis of microvesicles derived from human mesenchymal stem cells Mesenchymal stem cells Protein Differential centrifugation
Ultrafiltration
Ultracentrifugation
Sucrose density gradient
Optiprep density gradient
Microvesicles
466 Vesiclepedia_518 23585443 Homo sapiens Proteome profiling of exosomes derived from human primary and metastatic colorectal cells reveal differential expression of key metastatic factors and signal transduction components. Colorectal cancer cells Protein - Exosomes/Membrane vesicles
467 Vesiclepedia_331 19627513 Homo sapiens Exosomes from human saliva as a source of microRNA biomarkers Saliva Protein
miRNA
Differential centrifugation
Ultracentrifugation
Exosomes
468 Vesiclepedia_23 11231627 Mus musculus Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming. Mammary adenocarcinoma Protein Differential centrifugation
Sucrose density gradient
Exosomes
469 Vesiclepedia_145 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells Protein Sucrose density gradient Exosomes
470 Vesiclepedia_55 12147373 Homo sapiens Malignant effusions and immunogenic tumour-derived exosomes. Malignant pleural effusions Protein Differential centrifugation
Sucrose density gradient
Exosomes
471 Vesiclepedia_438 22114730 Staphylococcus aureus Staphylococcus aureus produces membrane-derived vesicles that induce host cell death. Staphylococcus aureus Protein - Membrane vesicles/Nanovesicles
472 Vesiclepedia_267 12757771 Homo sapiens Endothelial cells release phenotypically and quantitatively distinct microparticles in activation and apoptosis Endothelial cells Protein Differential centrifugation
FACS
Microparticles
473 Vesiclepedia_434 22014850 Rattus norvegicus Proteomics of microparticles after experimental pulmonary embolism. Plasma Protein - Microparticles
474 Vesiclepedia_378 18346024 Homo sapiens The proteome of red cell membranes and vesicles during storage in blood bank conditions. Red blood cells Protein - Microvesicles/Nanovesicles
475 Vesiclepedia_601 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Kidney cancer cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
476 Vesiclepedia_485 23214914 Trypanosoma cruzi Proteomic analysis of Trypanosoma cruzi secretome: characterization of two populations of extracellular vesicles and soluble proteins. Metacyclic trypomastigotes Protein - Exosomes/Extracellular vesicles/Ectosomes
477 Vesiclepedia_538 23844026 Homo sapiens Characterization of human thymic exosomes. Thymus Protein - Exosomes
478 Vesiclepedia_119 21362503 Homo sapiens Protein profile of exosomes from trabecular meshwork cells. Urine Protein Differential centrifugation
Sucrose density gradient
Exosomes
479 Vesiclepedia_201 21606166 Homo sapiens Blast-derived microvesicles in sera from patients with acute myeloid leukemia suppress natural killer cell function via membrane-associated transforming growth factor-beta2 Serum Protein Size exclusion chromatography
Ultracentrifugation
Microvesicles
480 Vesiclepedia_385 18563738 Homo sapiens Comparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles. Endothelial cells Protein - Microparticles
481 Vesiclepedia_33 21136642 Mus musculus Oligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons? Oligodendrocytes Protein Differential centrifugation
Sucrose density gradient
Exosomes
482 Vesiclepedia_236 10648405 Homo sapiens Cellular origin and procoagulant properties of microparticles in meningococcal sepsis Plasma Protein Differential centrifugation
FACS
Microparticles
483 Vesiclepedia_603 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Leukemia cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
484 Vesiclepedia_429 21595033 Homo sapiens Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy. Urine Protein - Exosomes
485 Vesiclepedia_633 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Prostate cancer cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
486 Vesiclepedia_280 15499615 Homo sapiens Microvesicles derived from activated platelets induce metastasis and angiogenesis in lung cancer Lung cancer cells Protein
mRNA
Differential centrifugation
FACS
Microvesicles
487 Vesiclepedia_454 22669077 Homo sapiens The proteome of erythrocyte-derived microparticles from plasma: new clues for erythrocyte aging and vesiculation. Blood Protein - Microparticles
488 Vesiclepedia_246 18425114 Homo sapiens Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells Glioblastoma cells Protein Differential centrifugation
Ultracentrifugation
Microvesicles
489 Vesiclepedia_277 22030351 Homo sapiens Expression of PTRF in PC-3 cells modulates cholesterol dynamics and the actin cytoskeleton impacting secretion pathways Prostate cancer cells Protein Differential centrifugation Exosomes
490 Vesiclepedia_594 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Kidney cancer cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
491 Vesiclepedia_493 23333927 Homo sapiens Characterization and proteomic analysis of ovarian cancer-derived exosomes. Ovarian cancer cells Protein - Exosomes
492 Vesiclepedia_46 17641064 Homo sapiens Exosomes with immune modulatory features are present in human breast milk. Breast milk Protein Differential centrifugation
Filtration
Sucrose density gradient
Exosomes
493 Vesiclepedia_353 24115447 Homo sapiens Comparative proteomics evaluation of plasma exosome isolation techniques and assessment of the stability of exosomes in normal human blood plasma Plasma Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
494 Vesiclepedia_383 18373357 Homo sapiens Isolation and identification of potential urinary microparticle biomarkers of bladder cancer. Urine Protein - Microparticles
495 Vesiclepedia_131 19188015 Homo sapiens Systemic presence and tumor-growth promoting effect of ovarian carcinoma released exosomes Ascites Protein
Lipids
Differential centrifugation
Sucrose density gradient
Exosomes
496 Vesiclepedia_293 10415024 Homo sapiens Activated human T cells release bioactive Fas ligand and APO2 ligand in microvesicles T cells Protein Differential centrifugation
Ultracentrifugation
FACS
Microvesicles
497 Vesiclepedia_159 21630462 Homo sapiens Proteomic analysis of microvesicles derived from human colorectal cancer ascites Ascites Protein Differential centrifugation
Sucrose density gradient
OptiPrep density gradient
Microvesicles
498 Vesiclepedia_271 10903724 Homo sapiens Follicular dendritic cells carry MHC class II-expressing microvesicles at their surface B cells Protein Differential centrifugation Exosomes
499 Vesiclepedia_372 17096383 Mus musculus Analysis of the extracellular matrix vesicle proteome in mineralizing osteoblasts. Osteoblasts Protein - Matrix vesicles
500 Vesiclepedia_386 18563738 Homo sapiens Comparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles. Endothelial cells Protein - Microparticles
501 Vesiclepedia_297 12796750 Homo sapiens High levels of circulating endothelial microparticles in patients with acute coronary syndromes Plasma Protein Differential centrifugation
FACS
Microparticles
502 Vesiclepedia_502 23436686 Homo sapiens A comprehensive characterization of membrane vesicles released by autophagic human endothelial cells. Endothelial cells Protein - Membrane vesicles/Extracellular vesicles
503 Vesiclepedia_186 22116803 Equus caballus Cell-Secreted Vesicles in Equine Ovarian Follicular Fluid Contain miRNAs and Proteins: A Possible New Form of Cell Communication Within the Ovarian Follicle Follicular fluid Protein
miRNA
Differential centrifugation
Ultracentrifugation
Microvesicles
504 Vesiclepedia_24 11231627 Homo sapiens Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming. Melanoma cells Protein Differential centrifugation
Sucrose density gradient
Exosomes
505 Vesiclepedia_367 12746840 Homo sapiens Proteomic analysis of human prostasomes. Seminal fluid Protein - Prostasomes
506 Vesiclepedia_390 19158352 Homo sapiens Characterization of PKD protein-positive exosome-like vesicles. Urine Protein - Exosomes/Membrane particles
507 Vesiclepedia_589 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Colon cancer cells Protein Serum-free medium
Differential centrifugation
polymer-based precipitation
Ultracenrifugation
Extracellular vesicles
508 Vesiclepedia_432 21751344 Pseudomonas aeruginosa Proteomic analysis of outer membrane vesicles derived from Pseudomonas aeruginosa. Pseudomonas aeruginosa Protein - Exosomes/Membrane vesicles
509 Vesiclepedia_469 23029346 Echinostoma caproni Extracellular Vesicles from Parasitic Helminths Contain Specific Excretory/Secretory Proteins and Are Internalized in Intestinal Host Cells. Echinostoma caproni Protein - Exosomes/Extracellular vesicles/Microvesicles
510 Vesiclepedia_252 9126269 Homo sapiens Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations T cells Protein Differential centrifugation
Sucrose density gradient
Microvesicles
511 Vesiclepedia_563 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells Protein Differential centrifugation
Ultracenrifugation
OptiPrep density gradient
Microvesicles