Browse results for content type: protein


 Vesiclepedia IDPubMed IDSpeciesExperiment descriptionSampleIdentificationsIsolation methodsVesicle type
1 Vesiclepedia_1261 24371517 Homo sapiens Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients. Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes
2 Vesiclepedia_1119 24391718 Homo sapiens Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
3 Vesiclepedia_1101 24513287 Mus musculus Lipid synthesis is promoted by hypoxic adipocyte-derived exosomes in 3T3-L1 cells. Serum Protein Differential centrifugation
Ultracentrifugation
Filtration
Exosomes
4 Vesiclepedia_1114 24391718 Homo sapiens Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
5 Vesiclepedia_608 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Lung cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
6 Vesiclepedia_171 21859146 Homo sapiens Identification of a conserved glycan signature for microvesicles Colorectal cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Microvesicles
7 Vesiclepedia_48 17641064 Homo sapiens Exosomes with immune modulatory features are present in human breast milk. Breast milk Protein Differential centrifugation
Filtration
Sucrose density gradient
Exosomes
8 Vesiclepedia_1283 22345510 Rattus norvegicus Characterization of membrane-shed microvesicles from cytokine-stimulated .-cells using proteomics strategies. Insulinoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes
9 Vesiclepedia_933 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. Bladder cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
10 Vesiclepedia_1210 29127410 Homo sapiens Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. Bronchial epithelial cells Protein Ultrafiltration
Size exclusion chromatography
Extracellular vesicles
11 Vesiclepedia_1170 29907695 Mus musculus Cancer cells copy migratory behavior and exchange signaling networks via extracellular vesicles. Melanoma cells Protein
miRNA
Differential centrifugation
Ultracentrifugation
Extracellular vesicles
12 Vesiclepedia_1111 24391718 Homo sapiens Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
13 Vesiclepedia_580 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Brain cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
14 Vesiclepedia_94 21828046 Rattus norvegicus The proteo-lipidic composition of exosomes changes during reticulocyte maturation. Reticulocytes Protein
Lipids
Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
15 Vesiclepedia_1001 24079734 Mus musculus Immunostimulatory activity of murine keratinocyte-derived exosomes. Keratinocytes Protein Differential centrifugation
Ultracentrifugation
Exosomes
16 Vesiclepedia_957 27601599 Homo sapiens Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. Breast milk Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Extracellular vesicles
17 Vesiclepedia_1021 20332430 Homo sapiens Proteomic analysis of prostate cancer metastasis-derived prostasomes. Skeletal tissue Protein Differential centrifugation
Ultracentrifugation
Prostasomes
18 Vesiclepedia_20 17956143 Homo sapiens Proteomic analysis of microvesicles derived from human colorectal cancer cells. Colorectal cancer cells Protein Differential centrifugation
Sucrose density gradient
Diafiltration
Exosomes
19 Vesiclepedia_1005 23463506 Homo sapiens The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes. T cells Protein Differential centrifugation
Ultracentrifugation
Exosomes
20 Vesiclepedia_196 21668449 Mus musculus SV31 is a Zn2+-binding synaptic vesicle protein Pheochromocytoma cells Protein Differential centrifugation
Sucrose density gradient
Large dense core vesicles
21 Vesiclepedia_211 21368175 Homo sapiens Cancer cell-derived microvesicles induce transformation by transferring tissue transglutaminase and fibronectin to recipient cells Glioma cells Protein Differential centrifugation
Filtration
Microvesicles
22 Vesiclepedia_1100 24513287 Mus musculus Lipid synthesis is promoted by hypoxic adipocyte-derived exosomes in 3T3-L1 cells. adipocytes Protein Differential centrifugation
Ultracentrifugation
Filtration
Exosomes
23 Vesiclepedia_781 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
24 Vesiclepedia_946 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. Urine Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
25 Vesiclepedia_40 15908444 Homo sapiens Exosomal-like vesicles are present in human blood plasma. Plasma Protein Differential centrifugation
Filtration
Sucrose density gradient
Exosomes
26 Vesiclepedia_633 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Prostate cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
27 Vesiclepedia_714 28811610 Homo sapiens Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. T cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Microvesicles
28 Vesiclepedia_624 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Melanoma cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
29 Vesiclepedia_1257 24400796 Homo sapiens Exosomal proteins in the aqueous humor as novel biomarkers in patients with neovascular age-related macular degeneration. Retinal pigment epithelial cells Protein ExoQuick Exosomes
30 Vesiclepedia_1220 27872147 Rattus norvegicus Primary Human and Rat .-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity. Insulinoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes
31 Vesiclepedia_790 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Embryonic kidney cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
32 Vesiclepedia_1026 22327366 Homo sapiens Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs. Vascular endothelial cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
33 Vesiclepedia_703 28811610 Homo sapiens Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. T cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Apoptotic bodies
34 Vesiclepedia_403 19548909 Homo sapiens Differential stimulation of monocytic cells results in distinct populations of microparticles. Monocytes Protein - Microparticles
35 Vesiclepedia_1237 25421927 Heligmosomoides polygyrus Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity. Heligmosomoides polygyrus miRNA
Protein
Filtration
Ultracentrifugation
Exosomes
36 Vesiclepedia_404 19548909 Homo sapiens Differential stimulation of monocytic cells results in distinct populations of microparticles. Monocytes Protein - Microparticles
37 Vesiclepedia_4 11487543 Homo sapiens Intestinal epithelial cells secrete exosome-like vesicles. Epithelial cells Protein Differential centrifugation
Sucrose density gradient
Exosomes
38 Vesiclepedia_1108 24391718 Homo sapiens Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Prostate epithelial cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
39 Vesiclepedia_676 29951053 Mus musculus Immunoregulatory Effects of Myeloid-Derived Suppressor Cell Exosomes in Mouse Model of Autoimmune Alopecia Areata. Myeloid-derived suppressor cells Protein Ultracentrifugation
Density gradient centrifugation
Exosomes
40 Vesiclepedia_245 9126269 Homo sapiens Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations T cells Protein
mRNA
Differential centrifugation
Sucrose density gradient
Microvesicles
41 Vesiclepedia_183 21741384 Homo sapiens A filtration-based protocol to isolate human plasma membrane-derived vesicles and exosomes from blood plasma Plasma Protein Differential centrifugation
Filtration
Microvesicles
42 Vesiclepedia_971 22808001 Homo sapiens Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment. Serum Protein Filtration
ExoQuick
Exosomes
43 Vesiclepedia_903 25053844 Homo sapiens Activity-associated miRNA are packaged in Map1b-enriched exosomes released from depolarized neurons Neuroblastoma cells Protein Differential centrifugation
Ultracentrifugation
Filtration
Exosomes
44 Vesiclepedia_1215 27872147 Rattus norvegicus Primary Human and Rat .-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity. Islets Protein Differential centrifugation
Ultracentrifugation
Exosomes
45 Vesiclepedia_832 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Differential centrifugation
Filtration
ExoQuick
Ultracentrifugation
Exosomes
46 Vesiclepedia_313 15499615 Homo sapiens Microvesicles derived from activated platelets induce metastasis and angiogenesis in lung cancer Lung cancer cells Protein Differential centrifugation
FACS
Microvesicles
47 Vesiclepedia_470 23029346 Fasciola hepatica Extracellular Vesicles from Parasitic Helminths Contain Specific Excretory/Secretory Proteins and Are Internalized in Intestinal Host Cells. Fasciola hepatica Protein - Exosomes/Extracellular vesicles/Microvesicles
48 Vesiclepedia_1035 29887978 Homo sapiens Evaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing. Serum Protein
miRNA
Exo-spin Extracellular vesicles
49 Vesiclepedia_1013 22711894 Homo sapiens Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages. Macrophages Protein
Lipids
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
50 Vesiclepedia_282 19234131 Homo sapiens Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR Lung cancer cells Protein Differential centrifugation Microvesicles
51 Vesiclepedia_671 29953960 Homo sapiens Exosomes derived from calcium oxalate-exposed macrophages enhance IL-8 production from renal cells, neutrophil migration and crystal invasion through extracellular matrix. Macrophages Protein Microfiltration
Differential centrifugation
Ultracentrifugation
Exosomes
52 Vesiclepedia_697 28842968 Homo sapiens Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles. Colorectal cancer cells Protein Differential centrifugation
Ultracentrifugation
Microvesicles
53 Vesiclepedia_583 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Brain cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
54 Vesiclepedia_605 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Leukemia cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
55 Vesiclepedia_940 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. Urine Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
56 Vesiclepedia_986 25261472 Homo sapiens Complex N-linked glycans serve as a determinant for exosome/microvesicle cargo recruitment. Melanoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes/Microvesicles
57 Vesiclepedia_653 28290293 Homo sapiens Comparative proteomic analysis of milk-derived exosomes in human and bovine colostrum and mature milk samples by iTRAQ-coupled LC-MS/MS. Breast milk Protein Differential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Exosomes
58 Vesiclepedia_844 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
59 Vesiclepedia_399 19530224 Homo sapiens Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes. Keratinocytes Protein - Exosomes
60 Vesiclepedia_527 23660474 Homo sapiens Heterogeneity in neutrophil microparticles reveals distinct proteome and functional properties. Neutrophils Protein - Microparticles
61 Vesiclepedia_503 23459212 Bos taurus Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis. Bovine milk Protein - Exosomes
62 Vesiclepedia_824 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Filtration
Ultracentrifugation
Sucrose density gradient
Exosomes
63 Vesiclepedia_1042 27770278 Homo sapiens Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease. Glioblastoma cells Protein Differential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Extracellular vesicles
64 Vesiclepedia_700 28811610 Homo sapiens Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. T cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Microvesicles
65 Vesiclepedia_1040 27770278 Homo sapiens Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease. Glioblastoma cells Protein Differential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Extracellular vesicles
66 Vesiclepedia_550 24009881 Homo sapiens Quantitative proteomics of extracellular vesicles derived from human primary and metastatic colorectal cancer cells. Colorectal cancer cells Protein - Exosomes/Extracellular vesicles/Microvesicles/Ectosomes
67 Vesiclepedia_407 19834908 Staphylococcus aureus Gram-positive bacteria produce membrane vesicles: proteomics-based characterization of Staphylococcus aureus-derived membrane vesicles. Staphylococcus aureus Protein - Membrane vesicles
68 Vesiclepedia_922 25483805 Homo sapiens Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties Embryonic kidney cells Protein Differential centrifugation
Ultracentrifugation
Exosomes
69 Vesiclepedia_861 25776846 Homo sapiens Human thymic epithelial primary cells produce exosomes carrying tissue-restricted antigens Epithelial cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
70 Vesiclepedia_895 24946052 Homo sapiens Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment Lung cancer cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Extracellular vesicles
71 Vesiclepedia_200 21606166 Homo sapiens Blast-derived microvesicles in sera from patients with acute myeloid leukemia suppress natural killer cell function via membrane-associated transforming growth factor-beta1 Serum Protein Size exclusion chromatography
Ultracentrifugation
Microvesicles
72 Vesiclepedia_138 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells Protein Sucrose density gradient Exosomes
73 Vesiclepedia_480 23161513 Homo sapiens Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS. Colorectal cancer cells Protein - Exosomes
74 Vesiclepedia_842 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
75 Vesiclepedia_1120 24347249 Homo sapiens Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules. Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
ExoQuick
Exosomes
76 Vesiclepedia_720 26148937 Homo sapiens Proteomics profiling of cholangiocarcinoma exosomes: A potential role of oncogenic protein transferring in cancer progression. Cholangiocytes Protein Differential centrifugation
Ultracentrifugation
Filtration
Exosomes
77 Vesiclepedia_213 21372807 Rattus norvegicus Upregulation of lipid synthesis in small rat adipocytes by microvesicle-associated CD73 from large adipocytes Adipocytes Protein Differential centrifugation Microvesicles
78 Vesiclepedia_998 24355714 Homo sapiens Proteomic analysis and immune properties of exosomes released by macrophages infected with Mycobacterium avium. Leukemia cells Protein Differential centrifugation
Ultracentrifugation
Exosomes
79 Vesiclepedia_381 18346024 Homo sapiens The proteome of red cell membranes and vesicles during storage in blood bank conditions. Red blood cells Protein - Microvesicles/Nanovesicles
80 Vesiclepedia_1011 23185418 Homo sapiens Improved flow cytometric assessment reveals distinct microvesicle (cell-derived microparticle) signatures in joint diseases. Synovial fluid Protein Filtration
Ultracentrifugation
Microvesicles
81 Vesiclepedia_981 25458527 Homo sapiens Benchtop isolation and characterization of functional exosomes by sequential filtration Breast cancer cells Protein Sequential filtration Exosomes
82 Vesiclepedia_275 12021310 Homo sapiens Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles Melanoma cells Protein Differential centrifugation
Ultracentrifugation
Microvesicles
83 Vesiclepedia_153 22022598 Homo sapiens Syncytiotrophoblast microvesicles released from pre-eclampsia placentae exhibit increased tissue factor activity Placenta Protein Differential centrifugation Microvesicles
84 Vesiclepedia_158 21630462 Homo sapiens Proteomic analysis of microvesicles derived from human colorectal cancer ascites Ascites Protein Differential centrifugation
Sucrose density gradient
OptiPrep density gradient
Microvesicles
85 Vesiclepedia_990 25261472 Homo sapiens Complex N-linked glycans serve as a determinant for exosome/microvesicle cargo recruitment. Melanoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes/Microvesicles
86 Vesiclepedia_1236 25421927 Heligmosomoides polygyrus Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity. Heligmosomoides polygyrus miRNA
Protein
Filtration
Ultracentrifugation
Exosomes
87 Vesiclepedia_306 16342139 Homo sapiens Proteomic analysis of malignant lymphocyte membrane microparticles using double ionization coverage optimization T cells Protein Differential centrifugation Microparticles
88 Vesiclepedia_1018 22399603 Homo sapiens Proteomic analysis of exosome-like vesicles derived from breast cancer cells. Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
89 Vesiclepedia_591 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Colorectal cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
90 Vesiclepedia_18 11907077 Homo sapiens TCR activation of human T cells induces the production of exosomes bearing the TCR/CD3/zeta complex. T cells Protein Filtration
Ultracentrifugation
Exosomes
91 Vesiclepedia_296 12796750 Homo sapiens High levels of circulating endothelial microparticles in patients with acute coronary syndromes Plasma Protein Differential centrifugation
FACS
Microparticles
92 Vesiclepedia_969 25844599 Homo sapiens Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. Serum Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
93 Vesiclepedia_742 28524762 Rattus norvegicus Exosomes promote restoration after an experimental animal model of intracerebral hemorrhage Mesenchymal stem cells Protein miRCURY Exosome Isolation Kit Exosomes
94 Vesiclepedia_152 22064971 Homo sapiens Oxidized low-density lipoprotein-dependent platelet-derived microvesicles trigger procoagulant effects and amplify oxidative stress Platelets Protein Differential centrifugation Microvesicles
95 Vesiclepedia_917 28687758 Sus scrofa Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers Polarised retinal pigmented epithelial cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
96 Vesiclepedia_72 19801663 Homo sapiens Microenvironmental pH is a key factor for exosome traffic in tumor cells. Melanoma cells Protein
Lipids
Differential centrifugation Exosomes
97 Vesiclepedia_945 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. Urine Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
98 Vesiclepedia_184 21672581 Rattus norvegicus Oxygen-glucose deprivation increases the enzymatic activity and the microvesicle-mediated release of ectonucleotidases in the cells composing the blood-brain barrier Astrocytes Protein Differential centrifugation Microvesicles
99 Vesiclepedia_24 11231627 Homo sapiens Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming. Melanoma cells Protein Differential centrifugation
Sucrose density gradient
Exosomes
100 Vesiclepedia_1147 23173708 Rattus norvegicus Wnt3a induces exosome secretion from primary cultured rat microglia. Primary microglial cells Protein Differential centrifugation
Ultracentrifugation
Exosomes
101 Vesiclepedia_1 6307529 Ovis aries Fate of the transferrin receptor during maturation of sheep reticulocytes in vitro: selective externalization of the receptor. Reticulocytes Protein - Exosomes
102 Vesiclepedia_879 29955024 Homo sapiens Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells Myeloid leukemia cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
103 Vesiclepedia_402 19548909 Homo sapiens Differential stimulation of monocytic cells results in distinct populations of microparticles. Monocytes Protein - Microparticles
104 Vesiclepedia_1130 23954818 Homo sapiens Qualitative changes in the proteome of extracellular vesicles accompanying cancer cell transition to mesenchymal state. Squamous carcinoma cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
105 Vesiclepedia_300 19234131 Homo sapiens Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR Epidermoid carcinoma cells Protein Differential centrifugation Microvesicles
106 Vesiclepedia_81 20458337 Homo sapiens MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 3 B cells Protein Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Exosomes
107 Vesiclepedia_335 20976003 Homo sapiens Selective release of microRNA species from normal and malignant mammary epithelial cells Breast cancer cells Protein
miRNA
Differential centrifugation
Filtration
Exosomes
108 Vesiclepedia_471 23035643 Drosophila melanogaster Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes. Drosophila S2 cells Protein - Exosomes
109 Vesiclepedia_260 10888925 Homo sapiens Transfer of the chemokine receptor CCR5 between cells by membrane-derived microparticles: a mechanism for cellular human immunodeficiency virus 1 infection Mononuclear cells Protein Differential centrifugation
Filtration
Microparticles
110 Vesiclepedia_323 20304794 Homo sapiens Functional delivery of viral miRNAs via exosomes B cells Protein Differential centrifugation Exosomes
111 Vesiclepedia_813 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Differential centrifugation
Filtration
ExoQuick
Ultracentrifugation
Exosomes
112 Vesiclepedia_535 23818640 Homo sapiens Modulation of B-cell exosome proteins by gamma herpesvirus infection. B cells Protein - Exosomes/Microvesicles/Oncosomes/Microparticles
113 Vesiclepedia_277 22030351 Homo sapiens Expression of PTRF in PC-3 cells modulates cholesterol dynamics and the actin cytoskeleton impacting secretion pathways Prostate cancer cells Protein Differential centrifugation Exosomes
114 Vesiclepedia_83 20949044 Homo sapiens Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line Lung cancer cells Protein
miRNA
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
115 Vesiclepedia_1050 28842968 Homo sapiens Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles. Colorectal cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
116 Vesiclepedia_1250 24939845 Homo sapiens Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein. Leukemia cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
117 Vesiclepedia_980 25471885 Drosophila melanogaster The ESCRT machinery regulates the secretion and long-range activity of Hedgehog. Drosophila wing imaginal Disc Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Extracellular vesicles
118 Vesiclepedia_566 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells Protein Differential centrifugation
Ultracentrifugation
Immunobeads (Igg1 PD)
Extracellular vesicles
119 Vesiclepedia_1053 29115712 Mus musculus Proteomic Profiling of Exosomes Secreted by Breast Cancer Cells with Varying Metastatic Potential. Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes
120 Vesiclepedia_454 22669077 Homo sapiens The proteome of erythrocyte-derived microparticles from plasma: new clues for erythrocyte aging and vesiculation. Plasma Protein - Microparticles
121 Vesiclepedia_913 28687758 Sus scrofa Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers Polarised retinal pigmented epithelial cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
122 Vesiclepedia_544 23977379 Listeria monocytogenes Transcription Factor σ(B) Plays an Important Role in the Production of Extracellular Membrane-Derived Vesicles in Listeria monocytogenes. Listeria monocytogenes Protein - Membrane vesicles
123 Vesiclepedia_569 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells Protein Differential centrifugation
Ultracentrifugation
Immunobeads (CD9 FT)
Extracellular vesicles
124 Vesiclepedia_710 28811610 Homo sapiens Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. T cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Exosomes
125 Vesiclepedia_370 16456881 Neisseria meningitidis Outer membrane vesicles from group B Neisseria meningitidis delta gna33 mutant: proteomic and immunological comparison with detergent-derived outer membrane vesicles. Neisseria meningitidis Protein - Membrane vesicles
126 Vesiclepedia_748 29988836 Homo sapiens Ultrafiltration and size exclusion chromatography combined with asymmetrical-flow field-flow fractionation for the isolation and characterisation of extracellular vesicles from urine Urine Protein Filtration
Size exclusion chromatography
Extracellular vesicles
127 Vesiclepedia_1274 23807490 Homo sapiens Glioma microvesicles carry selectively packaged coding and non-coding RNAs which alter gene expression in recipient cells. Glioblastoma cells Protein
miRNA
Differential centrifugation Microvesicles
128 Vesiclepedia_472 23043909 Pseudomonas syringae Virulence factors are released in association with outer membrane vesicles of Pseudomonas syringae pv. tomato T1 during normal growth. Pseudomonas syringae Protein - Membrane vesicles
129 Vesiclepedia_932 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. Bladder cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
130 Vesiclepedia_82 20949044 Homo sapiens Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line Stomach cancer cells Protein
miRNA
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
131 Vesiclepedia_61 17133577 Mus musculus Association of citrullinated proteins with synovial exosomes. Synovial fluid Protein Differential centrifugation
Sucrose density gradient
Exosomes
132 Vesiclepedia_41 15908444 Homo sapiens Exosomal-like vesicles are present in human blood plasma. Mast cells Protein Differential centrifugation
Filtration
Sucrose density gradient
Exosomes
133 Vesiclepedia_1263 24371517 Homo sapiens Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients. Urine Protein Differential centrifugation
Ultracentrifugation
Exosomes
134 Vesiclepedia_301 19234131 Homo sapiens Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR Endothelial cells Protein Differential centrifugation Microvesicles
135 Vesiclepedia_743 29988836 Homo sapiens Ultrafiltration and size exclusion chromatography combined with asymmetrical-flow field-flow fractionation for the isolation and characterisation of extracellular vesicles from urine Urine Protein Filtration
Size exclusion chromatography
Extracellular vesicles
136 Vesiclepedia_897 26100252 Homo sapiens Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts Chronic lymphocytic leukemia cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Exosomes
137 Vesiclepedia_741 25157233 Homo sapiens Extravillous trophoblast cells-derived exosomes promote vascular smooth muscle cell migration. Placenta Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
138 Vesiclepedia_1012 22711894 Homo sapiens Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages. Macrophages Protein Differential centrifugation
Filtration
Ultracentrifugation
Microvesicles/Exosomes
139 Vesiclepedia_1016 22711894 Homo sapiens Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages. Macrophages Protein
Lipids
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
140 Vesiclepedia_392 19351151 Mus musculus Characterization of vesicles secreted from insulinoma NIT-1 cells. Pancreatic cells Protein - Exosomes
141 Vesiclepedia_1023 22327366 Homo sapiens Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs. Vascular endothelial cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
142 Vesiclepedia_108 21601258 Homo sapiens Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage. Ascites Protein
miRNA
Differential centrifugation
Sucrose density gradient
Immunobeads (EpCAM, CD24)
Exosomes
143 Vesiclepedia_747 29988836 Homo sapiens Ultrafiltration and size exclusion chromatography combined with asymmetrical-flow field-flow fractionation for the isolation and characterisation of extracellular vesicles from urine Urine Protein Filtration
Size exclusion chromatography
Extracellular vesicles
144 Vesiclepedia_619 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Melanoma cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
145 Vesiclepedia_79 20458337 Homo sapiens MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 1 B cells Protein Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Exosomes
146 Vesiclepedia_719 26148937 Homo sapiens Proteomics profiling of cholangiocarcinoma exosomes: A potential role of oncogenic protein transferring in cancer progression. Cholangiocarcinoma cells Protein Differential centrifugation
Ultracentrifugation
Filtration
Exosomes
147 Vesiclepedia_439 22129587 Bos taurus Bovine milk exosome proteome. Bovine milk Protein - Exosomes/Membrane vesicles
148 Vesiclepedia_763 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Exosomes
149 Vesiclepedia_923 25483805 Homo sapiens Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties Embryonic kidney cells Protein Differential centrifugation
Ultracentrifugation
Exosomes
150 Vesiclepedia_519 23585444 Homo sapiens Identification and characterization of proteins isolated from microvesicles derived from human lung cancer pleural effusions. Malignant pleural effusions Protein - Exosomes/Microvesicles/Ectosomes/Microparticles
151 Vesiclepedia_1244 25167841 Homo sapiens Antibody-coupled monolithic silica microtips for highthroughput molecular profiling of circulating exosomes. Serum Protein CD9 antibody to Mass Spectrometric Immunoassay monolith pipette tips Exosomes
152 Vesiclepedia_768 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
153 Vesiclepedia_1213 29127410 Homo sapiens Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. Bronchial epithelial cells Protein Ultracentrifugation Extracellular vesicles
154 Vesiclepedia_539 23853596 Trichomonas vaginalis Trichomonas vaginalis Exosomes Deliver Cargo to Host Cells and Mediate Host∶Parasite Interactions. Trichomonas vaginalis Protein - Exosomes/Microvesicles
155 Vesiclepedia_693 28170197 Homo sapiens Enhanced Cardioprotection by Human Endometrium Mesenchymal Stem Cells Driven by Exosomal MicroRNA-21 Bone marrow mesenchymal stem cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
156 Vesiclepedia_1063 30006486 Homo sapiens The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells. Astrocytoma cells Protein Filtration
Ultracentrifugation
Density gradient centrifugation
Extracellular vesicles
157 Vesiclepedia_724 25471207 Homo sapiens Intraluminal proteome and peptidome of human urinary extracellular vesicles. Urine Protein Differential centrifugation
Hydrostatic filtration dialysis
Ultrafiltration
Exosomes
158 Vesiclepedia_453 22635005 Homo sapiens Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. Melanoma cells Protein - Exosomes
159 Vesiclepedia_935 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. Urine Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
160 Vesiclepedia_798 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Embryonic kidney cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
161 Vesiclepedia_486 23230278 Homo sapiens Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids. Colorectal cancer cells Protein - Exosomes/Extracellular vesicles/Microvesicles
162 Vesiclepedia_1271 24058411 Homo sapiens Osteoprotegerin in exosome-like vesicles from human cultured tubular cells and urine. Proximal tubular epithelial cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
163 Vesiclepedia_274 12021310 Homo sapiens Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles Melanoma cells Protein Differential centrifugation
Ultracentrifugation
Microvesicles
164 Vesiclepedia_1259 24400796 Rattus norvegicus Exosomal proteins in the aqueous humor as novel biomarkers in patients with neovascular age-related macular degeneration. Retinal glial cells Protein ExoQuick Exosomes
165 Vesiclepedia_1149 22807456 Homo sapiens Quantitative proteomic analysis of exosomes from HIV-1-infected lymphocytic cells. Lymphocytes Protein Differential centrifugation
Ultracentrifugation
Exosomes
166 Vesiclepedia_31 10572093 Homo sapiens Activated platelets release two types of membrane vesicles: microvesicles by surface shedding and exosomes derived from exocytosis of multivesicular bodies and alpha-granules. Platelets Protein Differential centrifugation
Sucrose density gradient
Exosomes
167 Vesiclepedia_802 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types T cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
168 Vesiclepedia_740 25157233 Homo sapiens Extravillous trophoblast cells-derived exosomes promote vascular smooth muscle cell migration. Placenta choriocarcinoma cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
169 Vesiclepedia_746 29988836 Homo sapiens Ultrafiltration and size exclusion chromatography combined with asymmetrical-flow field-flow fractionation for the isolation and characterisation of extracellular vesicles from urine Urine Protein Filtration
Size exclusion chromatography
Extracellular vesicles
170 Vesiclepedia_78 20224111 Homo sapiens Proteomics analysis of bladder cancer exosomes. Urine Protein Differential centrifugation
Sucrose density gradient
Exosomes
171 Vesiclepedia_288 12196479 Homo sapiens Type 1 and type 2 diabetic patients display different patterns of cellular microparticles Plasma Protein
Lipids
Differential centrifugation
FACS
Microparticles
172 Vesiclepedia_231 2294986 Homo sapiens Direct detection of activated platelets and platelet-derived microparticles in humans Plasma Protein FACS Microparticles
173 Vesiclepedia_22 15940614 Homo sapiens Human colorectal cancer cells induce T-cell death through release of proapoptotic microvesicles: role in immune escape. Colorectal cancer cells Protein Differential centrifugation Exosomes
174 Vesiclepedia_215 21364924 Homo sapiens Thermal- and oxidative stress causes enhanced release of NKG2D ligand-bearing immunosuppressive exosomes in leukemia/lymphoma T and B cells B cells Protein Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Exosomes
175 Vesiclepedia_821 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Filtration
Ultracentrifugation
Sucrose and deuterium oxide density cushion
Exosomes
176 Vesiclepedia_711 28811610 Homo sapiens Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. T cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Microvesicles
177 Vesiclepedia_382 18373357 Homo sapiens Isolation and identification of potential urinary microparticle biomarkers of bladder cancer. Urine Protein - Microparticles
178 Vesiclepedia_1194 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer. Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
179 Vesiclepedia_869 24614226 Ovis aries Extracellular vesicles in luminal fluid of the ovine uterus Uterine luminal fluid Protein Differential centrifugation
Filtration
ExoQuick
Extracellular vesicles
180 Vesiclepedia_1267 24218614 Homo sapiens Unexpected gain of function for the scaffolding protein plectin due to mislocalization in pancreatic cancer. Pancreatic adenocarcinoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes
181 Vesiclepedia_588 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Colorectal cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
182 Vesiclepedia_236 10648405 Homo sapiens Cellular origin and procoagulant properties of microparticles in meningococcal sepsis Plasma Protein Differential centrifugation
FACS
Microparticles
183 Vesiclepedia_466 22966805 Acinetobacter baumannii Extracellular proteome of a highly invasive multidrug-resistant clinical strain of Acinetobacter baumannii. Acinetobacter baumannii Protein - Membrane vesicles
184 Vesiclepedia_1045 28725021 Bos taurus Bovine milk-derived exosomes from colostrum are enriched with proteins implicated in immune response and growth. Bovine milk Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
185 Vesiclepedia_485 23214914 Trypanosoma cruzi Proteomic analysis of Trypanosoma cruzi secretome: characterization of two populations of extracellular vesicles and soluble proteins. Metacyclic trypomastigotes Protein - Exosomes/Extracellular vesicles/Ectosomes
186 Vesiclepedia_278 10233897 Homo sapiens Elevated levels of circulating procoagulant microparticles in patients with paroxysmal nocturnal hemoglobinuria and aplastic anemia Platelets Protein
Lipids
Differential centrifugation
FACS
Microparticles
187 Vesiclepedia_226 12514112 Homo sapiens Intravascular tissue factor initiates coagulation via circulating microvesicles and platelets Platelets Protein Differential centrifugation Microvesicles
188 Vesiclepedia_406 19806257 Homo sapiens Proteomic and functional characterisation of platelet microparticle size classes. Platelets Protein - Microparticles
189 Vesiclepedia_786 29953723 Oncorhynchus tshawytscha Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Embryonic cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
190 Vesiclepedia_88 20949044 Homo sapiens Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line Stomach cancer cells Protein
miRNA
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
191 Vesiclepedia_1129 23954818 Homo sapiens Qualitative changes in the proteome of extracellular vesicles accompanying cancer cell transition to mesenchymal state. Squamous carcinoma cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
192 Vesiclepedia_1079 25104112 Homo sapiens Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. Plasma Protein Differential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Exosomes
193 Vesiclepedia_659 29982104 Mus musculus NRP-1 targeted and cargo-loaded exosomes facilitate simultaneous imaging and therapy of glioma in vitro and in vivo. Macrophages Protein Differential centrifugation
Ultracentrifugation
Ultrafiltration
Exosomes
194 Vesiclepedia_1069 29937354 Homo sapiens Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors. Glioblastoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes
195 Vesiclepedia_1163 29904572 Bos taurus A subset of extracellular vesicles carries the bulk of microRNAs in commercial dairy cow's milk. Bovine milk Protein
miRNA
Differential centrifugation
Density gradient centrifugation
Extracellular vesicles
196 Vesiclepedia_80 20458337 Homo sapiens MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis -Sample 2 B cells Protein Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Exosomes
197 Vesiclepedia_1278 22437826 Drosophila melanogaster Mechanism of evenness interrupted (Evi)-exosome release at synaptic boutons. Drosophila S2 cells Protein Ultracentrifugation
Density gradient centrifugation
Exosomes
198 Vesiclepedia_562 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells Protein Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Microvesicles
199 Vesiclepedia_1272 24058411 Homo sapiens Osteoprotegerin in exosome-like vesicles from human cultured tubular cells and urine. Urine Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
200 Vesiclepedia_279 16192427 Homo sapiens Circulating endothelial microparticles are associated with vascular dysfunction in patients with end-stage renal failure Plasma Protein Differential centrifugation
FACS
Microparticles
201 Vesiclepedia_1219 27872147 Homo sapiens Primary Human and Rat .-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity. Islets Protein Differential centrifugation
Ultracentrifugation
Exosomes
202 Vesiclepedia_71 19801663 Homo sapiens Microenvironmental pH is a key factor for exosome traffic in tumor cells. Melanoma cells Protein
Lipids
Differential centrifugation
Sucrose density gradient
Exosomes
203 Vesiclepedia_7 12626558 Mus musculus Mast cell-derived exosomes induce phenotypic and functional maturation of dendritic cells and elicit specific immune responses in vivo. Mast cells Protein Differential centrifugation Exosomes
204 Vesiclepedia_949 28819550 Mus musculus Effects of storage temperature on airway exosome integrity for diagnostic and functional analyses. Bronchoalveolar lavage fluid Protein Differential centrifugation
Ultracentrifugation
Exosomes
205 Vesiclepedia_412 20156641 Homo sapiens Proteomics of microparticles after deep venous thrombosis. Plasma Protein - Membrane vesicles/Microparticles
206 Vesiclepedia_1174 29881354 Rattus norvegicus Effects of Acute Aerobic Exercise on Rats Serum Extracellular Vesicles Diameter, Concentration and Small RNAs Content. Serum Protein
miRNA
ExoQuick Extracellular vesicles
207 Vesiclepedia_429 21595033 Homo sapiens Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy. Urine Protein - Exosomes
208 Vesiclepedia_673 29953960 Homo sapiens Exosomes derived from calcium oxalate-exposed macrophages enhance IL-8 production from renal cells, neutrophil migration and crystal invasion through extracellular matrix. Macrophages Protein Microfiltration
Differential centrifugation
Ultracentrifugation
Exosomes
209 Vesiclepedia_984 25287304 Candida albicans Compositional and immunobiological analyses of extracellular vesicles released by Candida albicans. Candida albicans Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
210 Vesiclepedia_1062 30006486 Homo sapiens The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells. Astrocytoma cells Protein Filtration
Ultracentrifugation
Density gradient centrifugation
Extracellular vesicles
211 Vesiclepedia_674 29953960 Homo sapiens Exosomes derived from calcium oxalate-exposed macrophages enhance IL-8 production from renal cells, neutrophil migration and crystal invasion through extracellular matrix. Macrophages Protein Microfiltration
Differential centrifugation
Ultracentrifugation
Exosomes
212 Vesiclepedia_131 19188015 Homo sapiens Systemic presence and tumor-growth promoting effect of ovarian carcinoma released exosomes Ascites Protein
Lipids
Differential centrifugation
Sucrose density gradient
Exosomes
213 Vesiclepedia_617 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Melanoma cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
214 Vesiclepedia_27 19109410 Homo sapiens Proteomic and immunologic analyses of brain tumor exosomes. Medulloblastoma cells Protein Differential centrifugation
Sucrose density gradient
Exosomes
215 Vesiclepedia_526 23660474 Homo sapiens Heterogeneity in neutrophil microparticles reveals distinct proteome and functional properties. Neutrophils Protein - Microparticles
216 Vesiclepedia_1125 24347249 Homo sapiens Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules. Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
ExoQuick
Exosomes
217 Vesiclepedia_1195 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer. Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
218 Vesiclepedia_791 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Embryonic kidney cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
219 Vesiclepedia_1234 25421927 Mus musculus Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity. Serum miRNA
Protein
Filtration
Ultracentrifugation
Exosomes
220 Vesiclepedia_534 23818640 Homo sapiens Modulation of B-cell exosome proteins by gamma herpesvirus infection. B cells Protein - Exosomes/Microvesicles/Oncosomes/Microparticles
221 Vesiclepedia_248 15741221 Homo sapiens Tissue-factor-bearing microvesicles arise from lipid rafts and fuse with activated platelets to initiate coagulation Monocytic leukemia cells Protein Differential centrifugation Microvesicles
222 Vesiclepedia_198 21555566 Homo sapiens Multiple recognition assay reveals prostasomes as promising plasma biomarkers for prostate cancer Plasma Protein Differential centrifugation
Ultracentrifugation
Gel chromatography
Microvesicles
223 Vesiclepedia_56 12147373 Homo sapiens Malignant effusions and immunogenic tumour-derived exosomes. Ascites Protein Differential centrifugation
Sucrose density gradient
Exosomes
224 Vesiclepedia_62 17133577 Mus musculus Association of citrullinated proteins with synovial exosomes. Synovial fluid Protein Differential centrifugation
Sucrose density gradient
Exosomes
225 Vesiclepedia_169 21859146 Homo sapiens Identification of a conserved glycan signature for microvesicles T cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Microvesicles
226 Vesiclepedia_174 21842121 Mus musculus Oligodendroglioma cells shed microvesicles which contain TRAIL as well as molecular chaperones and induce cell death in astrocytes Oligodendrocytes Protein Differential centrifugation Microvesicles
227 Vesiclepedia_992 24434149 Homo sapiens In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. Ovarian cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes
228 Vesiclepedia_660 29964051 Homo sapiens Cell-free therapy based on adipose tissue stem cell-derived exosomes promotes wound healing via the PI3K/Akt signaling pathway Adipose tissue-derived stem cells Protein Differential centrifugation
Ultracentrifugation
Exosomes
229 Vesiclepedia_577 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Breast cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
230 Vesiclepedia_491 23264574 Francisella novicida Production of Outer Membrane Vesicles and Outer Membrane Tubes by Francisella novicida. Francisella novicida Protein - Membrane vesicles
231 Vesiclepedia_179 20686450 Homo sapiens Comparison of three methods for isolation of urinary microvesicles to identify biomarkers of nephrotic syndrome Urine Protein Differential centrifugation
Ultracentrifugation
Microvesicles
232 Vesiclepedia_745 29988836 Homo sapiens Ultrafiltration and size exclusion chromatography combined with asymmetrical-flow field-flow fractionation for the isolation and characterisation of extracellular vesicles from urine Urine Protein Filtration
Size exclusion chromatography
Extracellular vesicles
233 Vesiclepedia_430 21595033 Homo sapiens Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy. Urine Protein - Exosomes
234 Vesiclepedia_968 25844599 Homo sapiens Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. Serum Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
235 Vesiclepedia_568 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells Protein Differential centrifugation
Ultracentrifugation
Immunobeads (CD9 PD)
Extracellular vesicles
236 Vesiclepedia_1004 23463506 Homo sapiens The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes. T cells Protein Differential centrifugation
Ultracentrifugation
Exosomes
237 Vesiclepedia_60 17700640 Mus musculus CD24 is a marker of exosomes secreted into urine and amniotic fluid. Urine Protein Differential centrifugation
Sucrose density gradient
Exosomes
238 Vesiclepedia_701 28811610 Homo sapiens Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. T cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Microvesicles
239 Vesiclepedia_1245 25167841 Homo sapiens Antibody-coupled monolithic silica microtips for highthroughput molecular profiling of circulating exosomes. Serum Protein CD9 antibody to Mass Spectrometric Immunoassay monolith pipette tips Exosomes
240 Vesiclepedia_481 23161513 Homo sapiens Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS. Colorectal cancer cells Protein - Exosomes
241 Vesiclepedia_17 11907077 Homo sapiens TCR activation of human T cells induces the production of exosomes bearing the TCR/CD3/zeta complex. T cells Protein Filtration
Ultracentrifugation
Exosomes
242 Vesiclepedia_438 22114730 Staphylococcus aureus Staphylococcus aureus produces membrane-derived vesicles that induce host cell death. Staphylococcus aureus Protein - Membrane vesicles/Nanovesicles
243 Vesiclepedia_707 28811610 Homo sapiens Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. T cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Exosomes
244 Vesiclepedia_851 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
245 Vesiclepedia_1226 26154623 Homo sapiens Size-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals Plasma Protein Size exclusion chromatography Extracellular vesicles
246 Vesiclepedia_54 14975938 Homo sapiens Proteomic analysis of exosomes isolated from human malignant pleural effusions. Malignant pleural effusions Protein Differential centrifugation
Sucrose density gradient
Exosomes
247 Vesiclepedia_796 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Embryonic kidney cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
248 Vesiclepedia_919 28687758 Sus scrofa Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers Polarised retinal pigmented epithelial cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
249 Vesiclepedia_1144 23454749 Homo sapiens BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression. Bone marrow mesenchymal stromal cells Protein Differential centrifugation
Ultracentrifugation
Filtration
ExoQuick
Exosomes
250 Vesiclepedia_829 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Filtration
Ultracentrifugation
Sucrose density gradient
Exosomes
251 Vesiclepedia_774 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes Protein Differential centrifugation Apoptotic bodies
252 Vesiclepedia_1156 21212511 Homo sapiens Proteomic analysis of two types of exosomes in human whole saliva. Saliva Protein Differential centrifugation
Filtration
Ultracentrifugation
Gel filtration
Exosomes
253 Vesiclepedia_178 20686450 Homo sapiens Comparison of three methods for isolation of urinary microvesicles to identify biomarkers of nephrotic syndrome Urine Protein Differential centrifugation
Ultrafiltration
Microvesicles
254 Vesiclepedia_483 23214914 Trypanosoma cruzi Proteomic analysis of Trypanosoma cruzi secretome: characterization of two populations of extracellular vesicles and soluble proteins. Epimastigotes Protein - Exosomes/Extracellular vesicles/Ectosomes
255 Vesiclepedia_928 25483805 Gallus gallus Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties Notochord cells Protein Differential centrifugation
Ultracentrifugation
Exosomes
256 Vesiclepedia_778 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
257 Vesiclepedia_995 24434149 Homo sapiens In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. Ovarian cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes
258 Vesiclepedia_893 24946052 Homo sapiens Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment Lung cancer cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Extracellular vesicles
259 Vesiclepedia_726 25471207 Homo sapiens Intraluminal proteome and peptidome of human urinary extracellular vesicles. Urine Protein Differential centrifugation
Hydrostatic filtration dialysis
Ultrafiltration
Exosomes
260 Vesiclepedia_384 18482993 Homo sapiens Protein composition of human epididymosomes collected during surgical vasectomy reversal: a proteomic and genomic approach. Epididymal fluid Protein - Prostasomes
261 Vesiclepedia_809 29932869 Mus musculus Exosomes derived from high-glucose-stimulated Schwann cells promote development of diabetic peripheral neuropathy Schwann cells protein Filtration
Differential centrifugation
Ultracentrifugation
Exosomes
262 Vesiclepedia_1288 20399774 Mus musculus C2C12 myoblasts release micro-vesicles containing mtDNA and proteins involved in signal transduction. Mouse myoblast Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Microvesicles
263 Vesiclepedia_123 21235781 Homo sapiens Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages. Plasma Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
264 Vesiclepedia_161 21901833 Drosophila melanogaster Proteomics analyses of microvesicles released by Drosophila Kc167 and S2 cells Hematocytes Protein
PTM Ubiquitination
Differential centrifugation
Sucrose density gradient
Ultracentrifugation
Microvesicles
265 Vesiclepedia_1282 22345510 Rattus norvegicus Characterization of membrane-shed microvesicles from cytokine-stimulated .-cells using proteomics strategies. Insulinoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes
266 Vesiclepedia_69 19812188 Rattus norvegicus Immature dendritic cell-derived exosomes rescue septic animals via milk fat globule epidermal growth factor VIII. Dendritic cells Protein Differential centrifugation
Sucrose density gradient
Exosomes
267 Vesiclepedia_1124 24347249 Homo sapiens Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules. Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
ExoQuick
Exosomes
268 Vesiclepedia_465 22909304 Pseudomonas aeruginosa Identification of proteins associated with the Pseudomonas aeruginosa biofilm extracellular matrix. Pseudomonas aeruginosa Protein - Membrane vesicles
269 Vesiclepedia_794 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Embryonic kidney cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
270 Vesiclepedia_109 21601258 Homo sapiens Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage. Malignant pleural effusions Protein
miRNA
Differential centrifugation
Sucrose density gradient
Immunobeads (EpCAM)
Exosomes
271 Vesiclepedia_1162 22641613 Homo sapiens Application of systems biology principles to protein biomarker discovery: urinary exosomal proteome in renal transplantation. Urine Protein Differential centrifugation
Ultracentrifugation
Exosomes
272 Vesiclepedia_795 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Embryonic kidney cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
273 Vesiclepedia_522 23645497 Canis lupus familiaris Oncogenic H-Ras reprograms Madin-Darby canine kidney (MDCK) cell-derived exosomal proteins following epithelial-mesenchymal transition. Kidney cells Protein - Exosomes/Extracellular vesicles
274 Vesiclepedia_616 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Lung cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
275 Vesiclepedia_259 18425114 Homo sapiens Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells Glioma cells Protein Differential centrifugation
Ultracentrifugation
Microvesicles
276 Vesiclepedia_860 25776846 Homo sapiens Human thymic epithelial primary cells produce exosomes carrying tissue-restricted antigens Epithelial cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
277 Vesiclepedia_1157 20662102 Mus musculus Proteomic analysis identifies highly antigenic proteins in exosomes from M. tuberculosis-infected and culture filtrate protein-treated macrophages. Macrophages Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Exosomes
278 Vesiclepedia_699 28811610 Homo sapiens Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. T cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Exosomes
279 Vesiclepedia_890 24946052 Homo sapiens Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment Lung cancer cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Extracellular vesicles
280 Vesiclepedia_630 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Ovarian cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
281 Vesiclepedia_1027 24211404 Homo sapiens Diabetic nephropathy induces changes in the proteome of human urinary exosomes as revealed by label-free comparative analysis. Urine Protein Ultracentrifugation
ExoQuick
Exosomes
282 Vesiclepedia_39 15210972 Mus musculus Cells release prions in association with exosomes. Mov neuroglial cell Protein Differential centrifugation
Sucrose density gradient
Exosomes
283 Vesiclepedia_1247 25167841 Homo sapiens Antibody-coupled monolithic silica microtips for highthroughput molecular profiling of circulating exosomes. Serum Protein CD9 antibody to Mass Spectrometric Immunoassay monolith pipette tips Exosomes
284 Vesiclepedia_1128 23954818 Homo sapiens Qualitative changes in the proteome of extracellular vesicles accompanying cancer cell transition to mesenchymal state. Squamous carcinoma cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
285 Vesiclepedia_867 24614226 Ovis aries Extracellular vesicles in luminal fluid of the ovine uterus Uterine luminal fluid Protein Differential centrifugation
Filtration
ExoQuick
Extracellular vesicles
286 Vesiclepedia_541 23935504 Homo sapiens A Novel Role for Pro-Coagulant Microvesicles in the Early Host Defense against Streptococcus pyogenes. Peripheral blood mononucelar cells Protein - Microvesicles
287 Vesiclepedia_1112 24391718 Homo sapiens Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
288 Vesiclepedia_224 10393703 Homo sapiens In vitro generation of endothelial microparticles and possible prothrombotic activity in patients with lupus anticoagulant Plasma Protein Differential centrifugation Microparticles
289 Vesiclepedia_100 21828046 Rattus norvegicus The proteo-lipidic composition of exosomes changes during reticulocyte maturation. Reticulocytes Protein
Lipids
Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
290 Vesiclepedia_256 9126269 Homo sapiens Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations Burkitt's lymphoma Protein Differential centrifugation
Sucrose density gradient
Microvesicles
291 Vesiclepedia_1143 23454749 Homo sapiens BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression. Bone marrow mesenchymal stromal cells Protein Differential centrifugation
Ultracentrifugation
Filtration
ExoQuick
Exosomes
292 Vesiclepedia_393 19369228 Homo sapiens Proteomic analysis reveals presence of platelet microparticles in endothelial progenitor cell cultures. Endothelial cells Protein - Microparticles
293 Vesiclepedia_135 2777884 Cavia porcellus Asymmetric Distribution of Phospholipids in the Membrane of Vesicles Released During In Vitro Maturation of Guinea Pig Reticulocytes: Evidence Precluding a Role for Aminophospholipid Translocase Reticulocytes Proteins
Lipids
Differential centrifugation
Ultracentrifugation
Exosomes
294 Vesiclepedia_999 24355714 Homo sapiens Proteomic analysis and immune properties of exosomes released by macrophages infected with Mycobacterium avium. Leukemia cells Protein Differential centrifugation
Ultracentrifugation
Exosomes
295 Vesiclepedia_43 17076679 Homo sapiens Specific isolation of placenta-derived exosomes from the circulation of pregnant women and their immunoregulatory consequences. Plasma Protein Size exclusion chromatography
Ultracentrifugation
Immunobeads (CD3, CD19, CD56, CD83, PLAP)
Exosomes
296 Vesiclepedia_752 29963269 Homo sapiens Mining of potential microRNAs with clinical correlation - regulation of syndecan-1 expression by miR-122-5p altered mobility of breast cancer cells and possible correlation with liver injury Hepatoma cells Protein Total Exosome Isolation Kit
Differential centrifugation
Exosomes
297 Vesiclepedia_839 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
298 Vesiclepedia_732 25359493 Homo sapiens Proteomic signatures of extracellular vesicles secreted by nonmineralizing and mineralizing human osteoblasts and stimulation of tumor cell growth. Osteoblasts Protein Differential centrifugation
Ultracentrifugation
Matrix vesicles
299 Vesiclepedia_955 27601599 Homo sapiens Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. Breast milk Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Extracellular vesicles
300 Vesiclepedia_947 28819550 Mus musculus Effects of storage temperature on airway exosome integrity for diagnostic and functional analyses. Bronchoalveolar lavage fluid Protein Differential centrifugation
Ultracentrifugation
Exosomes
301 Vesiclepedia_974 22808001 Homo sapiens Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment. Serum Protein Filtration
ExoQuick
Exosomes
302 Vesiclepedia_866 24614226 Ovis aries Extracellular vesicles in luminal fluid of the ovine uterus Uterine luminal fluid Protein Differential centrifugation
Filtration
ExoQuick
Extracellular vesicles
303 Vesiclepedia_467 23000592 Homo sapiens In-depth analysis of the secretome identifies three major independent secretory pathways in differentiating human myoblasts. Neonatal myoblast cells Protein - Microvesicles/Nanovesicles
304 Vesiclepedia_855 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
305 Vesiclepedia_91 21252909 Homo sapiens Diacylglycerol kinase a regulates the formation and polarisation of mature multivesicular bodies involved in the secretion of Fas ligand-containing exosomes in T lymphocytes T cells Protein
Lipids
Differential centrifugation
Ultracentrifugation
Exosomes
306 Vesiclepedia_36 19367702 Mus musculus Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes. Hepatocytes Protein Differential centrifugation
Filtration
Exosomes
307 Vesiclepedia_415 20687614 Myxococcus xanthus Profiling the outer membrane proteome during growth and development of the social bacterium Myxococcus xanthus by selective biotinylation and analyses of outer membrane vesicles. Myxococcus xanthus Protein - Membrane vesicles
308 Vesiclepedia_578 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Breast cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
309 Vesiclepedia_921 28687758 Sus scrofa Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers Polarised retinal pigmented epithelial cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Extracellular vesicles
310 Vesiclepedia_502 23436686 Homo sapiens A comprehensive characterization of membrane vesicles released by autophagic human endothelial cells. Endothelial cells Protein - Membrane vesicles/Extracellular vesicles
311 Vesiclepedia_1258 24400796 Homo sapiens Exosomal proteins in the aqueous humor as novel biomarkers in patients with neovascular age-related macular degeneration. Aqueous humor Protein ExoQuick Exosomes
312 Vesiclepedia_1038 29887978 Homo sapiens Evaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing. Serum Protein
miRNA
miRCURY Exosome Isolation Kit Extracellular vesicles
313 Vesiclepedia_369 16212402 Homo sapiens The platelet microparticle proteome. Platelets Protein - Microparticles
314 Vesiclepedia_952 27601599 Homo sapiens Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. Breast milk Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Extracellular vesicles
315 Vesiclepedia_1067 29937354 Homo sapiens Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors. Glioblastoma cells Protein Differential centrifugation
Filtration
Microvesicles
316 Vesiclepedia_1132 23861904 Homo sapiens Exosomal signaling during hypoxia mediates microvascular endothelial cell migration and vasculogenesis. Placental mesenchymal stem cells Protein Differential centrifugation
Ultracentrifugation
Ultrafiltration
Density gradient centrifugation
Exosomes
317 Vesiclepedia_512 23533145 Homo sapiens In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Urine Protein - Exosomes/Microvesicles
318 Vesiclepedia_1256 24400796 Homo sapiens Exosomal proteins in the aqueous humor as novel biomarkers in patients with neovascular age-related macular degeneration. Retinal pigment epithelial cells Protein ExoQuick Exosomes
319 Vesiclepedia_991 25138791 Homo sapiens The exocyst and regulatory GTPases in urinary exosomes. Urine Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Extracellular vesicles
320 Vesiclepedia_353 24115447 Homo sapiens Comparative proteomics evaluation of plasma exosome isolation techniques and assessment of the stability of exosomes in normal human blood plasma Plasma Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
321 Vesiclepedia_193 21575145 Homo sapiens Microvesicle-mediated release of soluble LH/hCG receptor (LHCGR) from transfected cells and placenta explants Placenta Protein Differential centrifugation
Ultracentrifugation
Microvesicles
322 Vesiclepedia_1092 25065644 Homo sapiens Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells. Duodenal cancer cells Protein Differential centrifugation
Filtration
Ultrafiltration
Exosomes
323 Vesiclepedia_1071 29937354 Homo sapiens Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors. Glioblastoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes
324 Vesiclepedia_1155 21212511 Homo sapiens Proteomic analysis of two types of exosomes in human whole saliva. Saliva Protein Differential centrifugation
Filtration
Ultracentrifugation
Gel filtration
Exosomes
325 Vesiclepedia_792 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Embryonic kidney cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
326 Vesiclepedia_249 15741221 Homo sapiens Tissue-factor-bearing microvesicles arise from lipid rafts and fuse with activated platelets to initiate coagulation Monocytes Protein Differential centrifugation Microvesicles
327 Vesiclepedia_1154 22057275 Homo sapiens Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease. Cerebrospinal fluid Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Exosomes
328 Vesiclepedia_291 15072974 Rattus norvegicus Endothelium-derived microparticles impair endothelial function in vitro Endothelial cells Protein Differential centrifugation
Ultracentrifugation
FACS
Microparticles
329 Vesiclepedia_960 26047123 Bos taurus Oral administration of bovine milk derived extracellular vesicles attenuates arthritis in two mouse models. Bovine milk Protein Differential centrifugation
Ultracentrifugation
Filtration
Extracellular vesicles
330 Vesiclepedia_601 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Kidney cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
331 Vesiclepedia_1140 23454749 Homo sapiens BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression. Bone marrow mesenchymal stromal cells Protein Differential centrifugation
Ultracentrifugation
Filtration
ExoQuick
Exosomes
332 Vesiclepedia_1039 27770278 Homo sapiens Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease. Glioblastoma cells Protein Differential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Extracellular vesicles
333 Vesiclepedia_1032 29887978 Homo sapiens Evaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing. Serum Protein
miRNA
exoEasy columns Extracellular vesicles
334 Vesiclepedia_10 11390481 Mus musculus Proteomic analysis of dendritic cell-derived exosomes: a secreted subcellular compartment distinct from apoptotic vesicles. Dendritic cells Protein Differential centrifugation
Sucrose density gradient
Exosomes
335 Vesiclepedia_1158 20662102 Mus musculus Proteomic analysis identifies highly antigenic proteins in exosomes from M. tuberculosis-infected and culture filtrate protein-treated macrophages. Macrophages Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Exosomes
336 Vesiclepedia_772 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
337 Vesiclepedia_1168 29907695 Mus musculus Cancer cells copy migratory behavior and exchange signaling networks via extracellular vesicles. Melanoma cells Protein
miRNA
Differential centrifugation
Ultracentrifugation
Extracellular vesicles
338 Vesiclepedia_458 22740476 Homo sapiens Restoration of full-length APC protein in SW480 colon cancer cells induces exosome-mediated secretion of DKK-4. Colorectal cancer cells Protein - Exosomes
339 Vesiclepedia_261 12805058 Homo sapiens Sickle blood contains tissue factor-positive microparticles derived from endothelial cells and monocytes Plasma Protein
Lipids
Differential centrifugation
Ultracentrifugation
FACS
Microparticles
340 Vesiclepedia_285 12796750 Homo sapiens High levels of circulating endothelial microparticles in patients with acute coronary syndromes Plasma Protein Differential centrifugation
FACS
Microparticles
341 Vesiclepedia_967 25844599 Homo sapiens Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. Serum Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
342 Vesiclepedia_102 21082674 Homo sapiens Comprehensive analysis of low-abundance proteins in human urinary exosomes using peptide ligand library technology, peptide OFFGEL fractionation and nanoHPLC-chip-MS/MS. Urine Protein Differential centrifugation
Ultracentrifugation
Exosomes
343 Vesiclepedia_661 29956871 Homo sapiens Expression analysis of extracellular microRNA in bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis Bronchoalveolar lavage fluid Protein Differential centrifugation
Ultracentrifugation
Filtration
Exosomes
344 Vesiclepedia_1030 26378940 Homo sapiens Redefining the Breast Cancer Exosome Proteome by Tandem Mass Tag Quantitative Proteomics and Multivariate Cluster Analysis. Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Extracellular vesicles
345 Vesiclepedia_1115 24391718 Homo sapiens Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
346 Vesiclepedia_371 16456881 Neisseria meningitidis Outer membrane vesicles from group B Neisseria meningitidis delta gna33 mutant: proteomic and immunological comparison with detergent-derived outer membrane vesicles. Neisseria meningitidis Protein - Membrane vesicles
347 Vesiclepedia_850 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
348 Vesiclepedia_111 21601258 Homo sapiens Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage. Serum Protein
miRNA
Differential centrifugation
Sucrose density gradient
Immunobeads (CD24)
Exosomes
349 Vesiclepedia_987 25261472 Homo sapiens Complex N-linked glycans serve as a determinant for exosome/microvesicle cargo recruitment. Melanoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes/Microvesicles
350 Vesiclepedia_1091 25065644 Homo sapiens Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells. Duodenal cancer cells Protein Differential centrifugation
Filtration
Ultrafiltration
Exosomes
351 Vesiclepedia_1238 25329303 Homo sapiens Rapid isolation of extracellular vesicles from cell culture and biological fluids using a synthetic peptide with specific affinity for heat shock proteins. Urine Protein Ultracentrifugation Extracellular vesicles
352 Vesiclepedia_76 20224111 Homo sapiens Proteomics analysis of bladder cancer exosomes. Bladder cancer cells Protein Differential centrifugation
Sucrose density gradient
Exosomes
353 Vesiclepedia_1068 29937354 Homo sapiens Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors. Glioblastoma cells Protein Differential centrifugation
Filtration
Microvesicles
354 Vesiclepedia_873 24614226 Ovis aries Extracellular vesicles in luminal fluid of the ovine uterus Uterine luminal fluid Protein Differential centrifugation
Filtration
ExoQuick
Extracellular vesicles
355 Vesiclepedia_830 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Filtration
Ultracentrifugation
Sucrose density gradient
Exosomes
356 Vesiclepedia_273 12021310 Homo sapiens Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles T cells Protein Differential centrifugation
Ultracentrifugation
Microvesicles
357 Vesiclepedia_934 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. Bladder cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
358 Vesiclepedia_25 15111327 Homo sapiens Proteomic analysis of exosomes secreted by human mesothelioma cells. Mesothelioma cells Protein Differential centrifugation Exosomes
359 Vesiclepedia_180 20686450 Homo sapiens Comparison of three methods for isolation of urinary microvesicles to identify biomarkers of nephrotic syndrome Urine Protein Differential centrifugation
Ultracentrifugation
Size exclusion chromatography
Filtration
Microvesicles
360 Vesiclepedia_144 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells Protein Sucrose density gradient Exosomes
361 Vesiclepedia_834 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Differential centrifugation
Filtration
ExoQuick
Ultracentrifugation
Exosomes
362 Vesiclepedia_114 21557262 Homo sapiens Proteomic identification of exosomal LRG1: A potential urinary biomarker for detecting NSCLC. Urine Protein Differential centrifugation
Ultracentrifugation
Exosomes
363 Vesiclepedia_189 21741384 Homo sapiens A filtration-based protocol to isolate human plasma membrane-derived vesicles and exosomes from blood plasma Plasma Protein Differential centrifugation
Filtration
Exosomes
364 Vesiclepedia_346 22965126 Mus musculus Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells. Neuronal cells Protein
miRNA
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
365 Vesiclepedia_1095 24976626 Homo sapiens Exosomal transfer from human renal proximal tubule cells to distal tubule and collecting duct cells. Renal proximal tubule cells Protein Differential centrifugation
Ultracentrifugation
Immunoaffinity
Exosomes
366 Vesiclepedia_414 20559436 Saccharomyces cerevisiae Characterization of yeast extracellular vesicles: evidence for the participation of different pathways of cellular traffic in vesicle biogenesis. Saccharomyces cerevisiae Protein - Extracellular vesicles
367 Vesiclepedia_524 23658846 Mus musculus Immunomodulatory impact of leishmania-induced macrophage exosomes: a comparative proteomic and functional analysis. Macrophages Protein - Exosomes
368 Vesiclepedia_1085 25104112 Homo sapiens Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. Plasma Protein Differential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Exosomes
369 Vesiclepedia_99 21828046 Rattus norvegicus The proteo-lipidic composition of exosomes changes during reticulocyte maturation. Reticulocytes Protein
Lipids
Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
370 Vesiclepedia_433 22014850 Rattus norvegicus Proteomics of microparticles after experimental pulmonary embolism. Plasma Protein - Microparticles
371 Vesiclepedia_771 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
372 Vesiclepedia_958 26196085 Homo sapiens Identification of prostate cancer biomarkers in urinary exosomes. Urine Protein Differential centrifugation
Ultracentrifugation
Filtration
Exosomes
373 Vesiclepedia_994 24434149 Homo sapiens In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. Ovarian cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes
374 Vesiclepedia_333 20976003 Homo sapiens Selective release of microRNA species from normal and malignant mammary epithelial cells Breast cancer cells Protein
miRNA
Differential centrifugation
Filtration
Exosomes
375 Vesiclepedia_464 22909304 Pseudomonas aeruginosa Identification of proteins associated with the Pseudomonas aeruginosa biofilm extracellular matrix. Pseudomonas aeruginosa Protein - Membrane vesicles
376 Vesiclepedia_240 10233897 Homo sapiens Elevated levels of circulating procoagulant microparticles in patients with paroxysmal nocturnal hemoglobinuria and aplastic anemia Platelets Protein
Lipids
Differential centrifugation
FACS
Microparticles
377 Vesiclepedia_655 28290293 Bos taurus Comparative proteomic analysis of milk-derived exosomes in human and bovine colostrum and mature milk samples by iTRAQ-coupled LC-MS/MS. Bovine milk Protein Differential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Exosomes
378 Vesiclepedia_1218 27872147 Homo sapiens Primary Human and Rat .-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity. Islets Protein Differential centrifugation
Ultracentrifugation
Exosomes
379 Vesiclepedia_167 21859146 Homo sapiens Identification of a conserved glycan signature for microvesicles T cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Microvesicles
380 Vesiclepedia_197 21616097 Homo sapiens Release of podocalyxin into the extracellular space. Role of metalloproteinases Testicular cancer cells Protein Differential centrifugation Microvesicles
381 Vesiclepedia_290 12196479 Homo sapiens Type 1 and type 2 diabetic patients display different patterns of cellular microparticles Plasma Protein
Lipids
Differential centrifugation
FACS
Microparticles
382 Vesiclepedia_272 8896411 Homo sapiens High shear stress can initiate both platelet aggregation and shedding of procoagulant containing microparticles Platelets Protein
Lipids
Differential centrifugation
FACS
Microparticles
383 Vesiclepedia_1082 25104112 Homo sapiens Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. Plasma Protein Differential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Exosomes
384 Vesiclepedia_112 21601258 Homo sapiens Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage. Serum Protein
miRNA
Differential centrifugation
Sucrose density gradient
Exosomes
385 Vesiclepedia_1148 23173708 Rattus norvegicus Wnt3a induces exosome secretion from primary cultured rat microglia. Primary microglial cells Protein Differential centrifugation
Ultracentrifugation
Exosomes
386 Vesiclepedia_336 20976003 Homo sapiens Selective release of microRNA species from normal and malignant mammary epithelial cells Breast cancer cells Protein
miRNA
Differential centrifugation
Filtration
Exosomes
387 Vesiclepedia_265 18425114 Homo sapiens Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells Endothelial cells Protein Differential centrifugation
Ultracentrifugation
Microvesicles
388 Vesiclepedia_1017 22711894 Homo sapiens Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages. Macrophages Protein
Lipids
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
389 Vesiclepedia_289 12196479 Homo sapiens Type 1 and type 2 diabetic patients display different patterns of cellular microparticles Plasma Protein
Lipids
Differential centrifugation
FACS
Microparticles
390 Vesiclepedia_418 21049385 Homo sapiens The plasma microparticle proteome. Plasma Protein - Microparticles
391 Vesiclepedia_37 10878338 Homo sapiens Direct immunosuppressive effects of EBV-encoded latent membrane protein 1. B cells Protein Differential centrifugation Exosomes
392 Vesiclepedia_518 23585443 Homo sapiens Proteome profiling of exosomes derived from human primary and metastatic colorectal cells reveal differential expression of key metastatic factors and signal transduction components. Colorectal cancer cells Protein - Exosomes/Membrane vesicles
393 Vesiclepedia_575 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Breast cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
394 Vesiclepedia_58 17700640 Homo sapiens CD24 is a marker of exosomes secreted into urine and amniotic fluid. Amniotic fluid Protein Differential centrifugation
Sucrose density gradient
Exosomes
395 Vesiclepedia_11 12519789 Homo sapiens Proteomic and biochemical analyses of human B cell-derived exosomes. Potential implications for their function and multivesicular body formation. B cells Protein
Lipids
Differential centrifugation
Sucrose density gradient
Exosomes
396 Vesiclepedia_864 22046311 Mus musculus Exosomes from Plasmodium yoelii-infected reticulocytes protect mice from lethal infections Plasma Protein Differential centrifugation
Filtration
Sucrose density gradient
Ultracentrifugation
Exosomes
397 Vesiclepedia_42 15908444 Homo sapiens Exosomal-like vesicles are present in human blood plasma. Bone marrow cells Protein Differential centrifugation
Filtration
Sucrose density gradient
Exosomes
398 Vesiclepedia_585 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Brain cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
399 Vesiclepedia_1047 28725021 Bos taurus Bovine milk-derived exosomes from colostrum are enriched with proteins implicated in immune response and growth. Bovine milk Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
400 Vesiclepedia_118 21362503 Homo sapiens Protein profile of exosomes from trabecular meshwork cells. Tabecular meshwork cells Protein Differential centrifugation
Sucrose density gradient
Exosomes
401 Vesiclepedia_181 20668554 Homo sapiens Microvesicles derived from adult human bone marrow and tissue specific mesenchymal stem cells shuttle selected pattern of miRNAs Mesenchymal stem cells Protein
miRNA
Differential centrifugation
Ultracentrifugation
Microvesicles
402 Vesiclepedia_421 21136987 Helicobacter pylori Proteomic and functional characterization of the outer membrane vesicles from the gastric pathogen Helicobacter pylori. Helicobacter pylori Protein - Membrane vesicles
403 Vesiclepedia_117 21505438 Homo sapiens Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells. Dendritic cells Protein
miRNA
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
404 Vesiclepedia_411 20124223 Homo sapiens Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes. Squamous carcinoma cells Protein - Exosomes
405 Vesiclepedia_884 29955024 Homo sapiens Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells Myeloid leukemia cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
406 Vesiclepedia_1240 25329303 Homo sapiens Rapid isolation of extracellular vesicles from cell culture and biological fluids using a synthetic peptide with specific affinity for heat shock proteins. Urine Protein Ultracentrifugation Extracellular vesicles
407 Vesiclepedia_431 21595033 Homo sapiens Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy. Urine Protein - Exosomes
408 Vesiclepedia_538 23844026 Homo sapiens Characterization of human thymic exosomes. Thymus Protein - Exosomes
409 Vesiclepedia_804 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types T cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
410 Vesiclepedia_107 21763319 Homo sapiens Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells. Pancreatic adenocarcinoma cells Protein Differential centrifugation
Filtration
Ultrafiltration
Ultracentrifugation
Exosomes
411 Vesiclepedia_318 19483673 Homo sapiens Y-box protein-1 is actively secreted through a non-classical pathway and acts as an extracellular mitogen Monocytes Protein Differential centrifugation
Filtration
Microvesicles
412 Vesiclepedia_825 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Filtration
Ultracentrifugation
Sucrose density gradient
Exosomes
413 Vesiclepedia_68 19619303 Homo sapiens Claudin-containing exosomes in the peripheral circulation of women with ovarian cancer. Plasma Protein Differential centrifugation Exosomes
414 Vesiclepedia_210 21368175 Homo sapiens Cancer cell-derived microvesicles induce transformation by transferring tissue transglutaminase and fibronectin to recipient cells Breast cancer cells Protein Differential centrifugation
Filtration
Microvesicles
415 Vesiclepedia_571 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells Protein Differential centrifugation
Ultracentrifugation
Immunobeads (CD63 FT)
Extracellular vesicles
416 Vesiclepedia_632 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Ovarian cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
417 Vesiclepedia_199 21609964 Homo sapiens Characterization of extracellular circulating microRNA Plasma Protein Differential centrifugation
Filtration
Exosomes
418 Vesiclepedia_886 25102470 Homo sapiens Examination of the specificity of tumor cell derived exosomes with tumor cells in vitro Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
419 Vesiclepedia_283 19234131 Homo sapiens Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR Colorectal cancer cells Protein Differential centrifugation Microvesicles
420 Vesiclepedia_1192 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer. Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
421 Vesiclepedia_728 25359493 Homo sapiens Proteomic signatures of extracellular vesicles secreted by nonmineralizing and mineralizing human osteoblasts and stimulation of tumor cell growth. Osteoblasts Protein Differential centrifugation
Ultracentrifugation
Matrix vesicles
422 Vesiclepedia_1010 23185418 Homo sapiens Improved flow cytometric assessment reveals distinct microvesicle (cell-derived microparticle) signatures in joint diseases. Synovial fluid Protein Filtration
Ultracentrifugation
Microvesicles
423 Vesiclepedia_65 19415654 Homo sapiens Proteomics of MUC1-containing lipid rafts from plasma membranes and exosomes of human breast carcinoma cells MCF-7. Breast cancer cells Protein Differential centrifugation
Sucrose density gradient
Exosomes
424 Vesiclepedia_876 29955024 Homo sapiens Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells Embryonic kidney cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
425 Vesiclepedia_1216 27872147 Rattus norvegicus Primary Human and Rat .-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity. Islets Protein Differential centrifugation
Ultracentrifugation
Exosomes
426 Vesiclepedia_444 22418980 Homo sapiens A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes. Urine Protein - Exosomes
427 Vesiclepedia_669 29953960 Homo sapiens Exosomes derived from calcium oxalate-exposed macrophages enhance IL-8 production from renal cells, neutrophil migration and crystal invasion through extracellular matrix. Macrophages Protein Microfiltration
Differential centrifugation
Ultracentrifugation
Exosomes
428 Vesiclepedia_6 11306949 Mus musculus Nonspecific B and T cell-stimulatory activity mediated by mast cells is associated with exosomes. Mast cells Protein - Exosomes
429 Vesiclepedia_191 21635979 Mus musculus Proteomic characterization of thymocyte-derived microvesicles and apoptotic bodies in BALB/c mice Thymus Protein Differential centrifugation
Filtration
Microvesicles
430 Vesiclepedia_157 21630462 Homo sapiens Proteomic analysis of microvesicles derived from human colorectal cancer ascites Ascites Protein Differential centrifugation
Sucrose density gradient
OptiPrep density gradient
Microvesicles
431 Vesiclepedia_389 18819103 Homo sapiens Structural heterogeneity and protein composition of exosome-like vesicles (prostasomes) in human semen. Seminal fluid Protein - Exosomes/Prostasomes
432 Vesiclepedia_223 10393703 Homo sapiens In vitro generation of endothelial microparticles and possible prothrombotic activity in patients with lupus anticoagulant Endothelial cells Protein Differential centrifugation
Ultracentrifugation
Microparticles
433 Vesiclepedia_64 18520029 Homo sapiens Exosome-like vesicles with dipeptidyl peptidase IV in human saliva. Saliva Protein Filtration
Diafiltration
Gel filtration
Exosomes
434 Vesiclepedia_670 29953960 Homo sapiens Exosomes derived from calcium oxalate-exposed macrophages enhance IL-8 production from renal cells, neutrophil migration and crystal invasion through extracellular matrix. Macrophages Protein Microfiltration
Differential centrifugation
Ultracentrifugation
Exosomes
435 Vesiclepedia_170 21859146 Homo sapiens Identification of a conserved glycan signature for microvesicles Colorectal cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Microvesicles
436 Vesiclepedia_827 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Filtration
Ultracentrifugation
Sucrose density gradient
Exosomes
437 Vesiclepedia_751 29988836 Homo sapiens Ultrafiltration and size exclusion chromatography combined with asymmetrical-flow field-flow fractionation for the isolation and characterisation of extracellular vesicles from urine Urine Protein Filtration
Size exclusion chromatography
Extracellular vesicles
438 Vesiclepedia_30 16446100 Rattus norvegicus Exosomes are released by cultured cortical neurones. Cortical neurones Protein Differential centrifugation
Sucrose density gradient
Exosomes
439 Vesiclepedia_976 22808001 Homo sapiens Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment. Serum Protein Filtration
ExoQuick
Exosomes
440 Vesiclepedia_219 10694520 Homo sapiens Elevated levels of shed membrane microparticles with procoagulant potential in the peripheral circulating blood of patients with acute coronary syndromes Plasma Protein Immunoaffinity [Annexin-V] Microparticles
441 Vesiclepedia_765 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
442 Vesiclepedia_1066 29963299 Homo sapiens Enrichment of extracellular vesicles from human synovial fluid using size exclusion chromatography. Synovial fluid Protein Size exclusion chromatography Extracellular vesicles
443 Vesiclepedia_1133 23861904 Homo sapiens Exosomal signaling during hypoxia mediates microvascular endothelial cell migration and vasculogenesis. Placental mesenchymal stem cells Protein Differential centrifugation
Ultracentrifugation
Ultrafiltration
Density gradient centrifugation
Exosomes
444 Vesiclepedia_695 28842968 Homo sapiens Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles. Colorectal cancer cells Protein Differential centrifugation
Ultracentrifugation
Microvesicles
445 Vesiclepedia_44 19028452 Homo sapiens Proteomic profiling of human plasma exosomes identifies PPARgamma as an exosome-associated protein. Plasma Protein Filtration
Size exclusion chromatography
Sucrose density gradient
Exosomes
446 Vesiclepedia_229 2942561 Homo sapiens Platelet surface glycoproteins. Studies on resting and activated platelets and platelet membrane microparticles in normal subjects, and observations in patients during adult respiratory distress syndrome and cardiac surgery Plasma Protein Differential centrifugation Microparticles
447 Vesiclepedia_964 25844599 Homo sapiens Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
448 Vesiclepedia_545 23983189 Homo sapiens Characterization of Multiple Myeloma Vesicles by Label-Free Relative Quantitation. B cells Protein - Exosomes/Extracellular vesicles/Microvesicles
449 Vesiclepedia_520 23601281 Homo sapiens Proteomic characterization of human platelet-derived microparticles. Platelets Protein - Microparticles
450 Vesiclepedia_304 17478559 Mus musculus Identification and characterization of microvesicles secreted by 3T3-L1 adipocytes: redox- and hormone-dependent induction of milk fat globule-epidermal growth 8-associated microvesicles Adipocytes Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Microvesicles
451 Vesiclepedia_1025 22327366 Homo sapiens Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs. Vascular endothelial cells Protein
miRNA
Differential centrifugation
Ultracentrifugation
Extracellular vesicles
452 Vesiclepedia_776 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes Protein Differential centrifugation Microvesicles
453 Vesiclepedia_925 25483805 Homo sapiens Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties Embryonic kidney cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
454 Vesiclepedia_1262 24371517 Homo sapiens Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients. Urine Protein Differential centrifugation
Ultracentrifugation
Exosomes
455 Vesiclepedia_38 15210972 Oryctolagus cuniculus Cells release prions in association with exosomes. Epithelial cells Protein Differential centrifugation
Sucrose density gradient
Exosomes
456 Vesiclepedia_863 22046311 Mus musculus Exosomes from Plasmodium yoelii-infected reticulocytes protect mice from lethal infections Plasma Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
457 Vesiclepedia_443 22329422 Homo sapiens Quantitative proteome profiling of normal human circulating microparticles. Plasma Protein - Microparticles
458 Vesiclepedia_910 28687758 Sus scrofa Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers Polarised retinal pigmented epithelial cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
459 Vesiclepedia_777 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
460 Vesiclepedia_513 23533145 Homo sapiens In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Urine Protein - Exosomes/Microvesicles
461 Vesiclepedia_134 15304316 Rattus norvegicus PLD2 is enriched on exosomes and its activity is correlated to the release of exosomes Basophilic leukemia cells Protein
Lipids
Differential centrifugation Exosomes
462 Vesiclepedia_187 22116803 Equus caballus Cell-Secreted Vesicles in Equine Ovarian Follicular Fluid Contain miRNAs and Proteins: A Possible New Form of Cell Communication Within the Ovarian Follicle Serum Protein Differential centrifugation
ExoQuick
Exosomes
463 Vesiclepedia_1230 25503107 Homo sapiens Tumor-derived microvesicles mediate human breast cancer invasion through differentially glycosylated EMMPRIN. Breast cancer cells Protein Ultracentrifugation
Filtration
Density gradient centrifugation
Microvesicles
464 Vesiclepedia_1083 25104112 Homo sapiens Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. Plasma Protein Differential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Exosomes
465 Vesiclepedia_590 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Colorectal cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
466 Vesiclepedia_293 10415024 Homo sapiens Activated human T cells release bioactive Fas ligand and APO2 ligand in microvesicles T cells Protein Differential centrifugation
Ultracentrifugation
FACS
Microvesicles
467 Vesiclepedia_620 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Melanoma cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
468 Vesiclepedia_892 24946052 Homo sapiens Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment Lung cancer cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Extracellular vesicles
469 Vesiclepedia_212 21372807 Rattus norvegicus Upregulation of lipid synthesis in small rat adipocytes by microvesicle-associated CD73 from large adipocytes Adipocytes Protein Differential centrifugation Microvesicles
470 Vesiclepedia_629 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Ovarian cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
471 Vesiclepedia_34 19190083 Homo sapiens Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense. Tracheobronchial cells Protein
mRNA
Differential centrifugation
Filtration
Sucrose density gradient
Exosomes
472 Vesiclepedia_901 26100252 Homo sapiens Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts Chronic lymphocytic leukemia cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Exosomes
473 Vesiclepedia_1126 24295599 Mus musculus Exosomes from myeloid-derived suppressor cells carry biologically active proteins. Myeloid-derived suppressor cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
474 Vesiclepedia_764 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
475 Vesiclepedia_355 24115447 Homo sapiens Comparative proteomics evaluation of plasma exosome isolation techniques and assessment of the stability of exosomes in normal human blood plasma Plasma Protein Differential centrifugation
Filtration
Ultracentrifugation
Immunoaffinity (EpCAM)
Exosomes
476 Vesiclepedia_540 23886663 Homo sapiens LRRK2 Secretion in Exosomes is Regulated by 14-3-3. Urine Protein - Exosomes/Microvesicles
477 Vesiclepedia_334 20976003 Homo sapiens Selective release of microRNA species from normal and malignant mammary epithelial cells Breast cancer cells Protein
miRNA
Differential centrifugation
Filtration
Exosomes
478 Vesiclepedia_1061 30006486 Homo sapiens The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells. Astrocytoma cells Protein Filtration
Ultracentrifugation
Density gradient centrifugation
Extracellular vesicles
479 Vesiclepedia_308 16342139 Homo sapiens Proteomic analysis of malignant lymphocyte membrane microparticles using double ionization coverage optimization B cells Protein Differential centrifugation Microparticles
480 Vesiclepedia_820 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Differential centrifugation
Filtration
ExoQuick
Ultracentrifugation
Exosomes
481 Vesiclepedia_628 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Ovarian cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
482 Vesiclepedia_66 19199708 Homo sapiens Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT). Saliva Protein Differential centrifugation Exosomes
483 Vesiclepedia_1064 30006486 Homo sapiens The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells. Astrocytoma cells Protein Filtration
Ultracentrifugation
Density gradient centrifugation
Extracellular vesicles
484 Vesiclepedia_374 18039940 Cryptococcus neoformans Extracellular vesicles produced by Cryptococcus neoformans contain protein components associated with virulence. Cryptococcus neoformans Protein - Exosomes/Extracellular vesicles
485 Vesiclepedia_1142 23454749 Homo sapiens BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression. Bone marrow mesenchymal stromal cells Protein Differential centrifugation
Ultracentrifugation
Filtration
ExoQuick
Exosomes
486 Vesiclepedia_979 25471885 Drosophila melanogaster The ESCRT machinery regulates the secretion and long-range activity of Hedgehog. Drosophila wing imaginal Disc Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Extracellular vesicles
487 Vesiclepedia_489 23260141 Mus musculus Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration. Fibroblasts Protein - Exosomes
488 Vesiclepedia_1098 24513287 Mus musculus Lipid synthesis is promoted by hypoxic adipocyte-derived exosomes in 3T3-L1 cells. adipocytes Protein Differential centrifugation
Ultracentrifugation
Filtration
Exosomes
489 Vesiclepedia_664 29956871 Homo sapiens Expression analysis of extracellular microRNA in bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis Bronchoalveolar lavage fluid Protein Differential centrifugation
Ultracentrifugation
Filtration
Microvesicles
490 Vesiclepedia_662 29956871 Homo sapiens Expression analysis of extracellular microRNA in bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis Bronchoalveolar lavage fluid Protein Differential centrifugation
Ultracentrifugation
Filtration
Microvesicles
491 Vesiclepedia_416 20687614 Myxococcus xanthus Profiling the outer membrane proteome during growth and development of the social bacterium Myxococcus xanthus by selective biotinylation and analyses of outer membrane vesicles. Myxococcus xanthus Protein - Membrane vesicles
492 Vesiclepedia_572 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells Protein Differential centrifugation
Ultracentrifugation
Immunobeads (CD81 PD)
Extracellular vesicles
493 Vesiclepedia_423 21138299 Francisella tularensis Proteomic characterization and functional analysis of outer membrane vesicles of Francisella novicida suggests possible role in virulence and use as a vaccine. Francisella tularensis Protein - Membrane vesicles
494 Vesiclepedia_525 23658846 Mus musculus Immunomodulatory impact of leishmania-induced macrophage exosomes: a comparative proteomic and functional analysis. Macrophages Protein - Exosomes
495 Vesiclepedia_173 21859146 Homo sapiens Identification of a conserved glycan signature for microvesicles Breast milk Protein Differential centrifugation
Filtration
Ultracentrifugation
Microvesicles
496 Vesiclepedia_490 23264574 Francisella novicida Production of Outer Membrane Vesicles and Outer Membrane Tubes by Francisella novicida. Francisella novicida Protein - Membrane vesicles
497 Vesiclepedia_218 10694520 Homo sapiens Elevated levels of shed membrane microparticles with procoagulant potential in the peripheral circulating blood of patients with acute coronary syndromes Plasma Protein Immunoaffinity [Annexin-V] Microparticles
498 Vesiclepedia_75 19381331 Homo sapiens High levels of exosomes expressing CD63 and caveolin-1 in plasma of melanoma patients. Plasma Protein Differential centrifugation Exosomes
499 Vesiclepedia_498 23376485 Homo sapiens Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. Urine Protein - Exosomes/Membrane vesicles
500 Vesiclepedia_951 27601599 Homo sapiens Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. Breast milk Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Extracellular vesicles
501 Vesiclepedia_819 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Differential centrifugation
Filtration
ExoQuick
Ultracentrifugation
Exosomes
502 Vesiclepedia_858 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Plasma Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
503 Vesiclepedia_115 21505438 Homo sapiens Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells. T cells Protein
miRNA
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
504 Vesiclepedia_250 9396452 Homo sapiens Cell-derived microparticles generated in patients during cardiopulmonary bypass are highly procoagulant Plasma Protein
Lipids
Differential centrifugation Microparticles
505 Vesiclepedia_871 24614226 Ovis aries Extracellular vesicles in luminal fluid of the ovine uterus Uterine luminal fluid Protein Differential centrifugation
Filtration
ExoQuick
Extracellular vesicles
506 Vesiclepedia_536 23818640 Homo sapiens Modulation of B-cell exosome proteins by gamma herpesvirus infection. B cells Protein - Exosomes/Microvesicles/Oncosomes/Microparticles
507 Vesiclepedia_836 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Differential centrifugation
Filtration
ExoQuick
Ultracentrifugation
Exosomes
508 Vesiclepedia_387 18563738 Homo sapiens Comparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles. Endothelial cells Protein - Microparticles
509 Vesiclepedia_811 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Differential centrifugation
Filtration
ExoQuick
Ultracentrifugation
Exosomes
510 Vesiclepedia_396 19413345 Homo sapiens Proteomic analysis of malignant B-cell derived microparticles reveals CD148 as a potentially useful antigenic biomarker for mantle cell lymphoma diagnosis. B cells Protein - Microparticles
511 Vesiclepedia_1264 24371517 Homo sapiens Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients. Urine Protein Differential centrifugation
Ultracentrifugation
Exosomes
512 Vesiclepedia_963 25844599 Homo sapiens Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
513 Vesiclepedia_663 29956871 Homo sapiens Expression analysis of extracellular microRNA in bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis Bronchoalveolar lavage fluid Protein Differential centrifugation
Ultracentrifugation
Filtration
Exosomes
514 Vesiclepedia_1041 27770278 Homo sapiens Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease. Glioblastoma cells Protein Differential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Extracellular vesicles
515 Vesiclepedia_899 26100252 Homo sapiens Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts Chronic lymphocytic leukemia cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Exosomes
516 Vesiclepedia_267 12757771 Homo sapiens Endothelial cells release phenotypically and quantitatively distinct microparticles in activation and apoptosis Endothelial cells Protein Differential centrifugation
FACS
Microparticles
517 Vesiclepedia_32 18452139 Homo sapiens Primary human keratinocytes externalize stratifin protein via exosomes. Keratinocytes Protein Differential centrifugation
Sucrose density gradient
Diafiltration
Exosomes
518 Vesiclepedia_1109 24391718 Homo sapiens Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Prostate epithelial cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
519 Vesiclepedia_1248 24939845 Homo sapiens Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein. Leukemia cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
520 Vesiclepedia_376 18346024 Homo sapiens The proteome of red cell membranes and vesicles during storage in blood bank conditions. Red blood cells Protein - Microvesicles/Nanovesicles
521 Vesiclepedia_119 21362503 Homo sapiens Protein profile of exosomes from trabecular meshwork cells. Urine Protein Differential centrifugation
Sucrose density gradient
Exosomes
522 Vesiclepedia_52 14975938 Homo sapiens Proteomic analysis of exosomes isolated from human malignant pleural effusions. Malignant pleural effusions Protein Differential centrifugation
Sucrose density gradient
Exosomes
523 Vesiclepedia_1209 29127410 Homo sapiens Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. Bronchial epithelial cells Protein Ultrafiltration
Size exclusion chromatography
Extracellular vesicles
524 Vesiclepedia_1136 23861904 Homo sapiens Exosomal signaling during hypoxia mediates microvascular endothelial cell migration and vasculogenesis. Placental mesenchymal stem cells Protein Differential centrifugation
Ultracentrifugation
Ultrafiltration
Density gradient centrifugation
Exosomes
525 Vesiclepedia_1211 29127410 Homo sapiens Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. Bronchial epithelial cells Protein Ultrafiltration
Size exclusion chromatography
Extracellular vesicles
526 Vesiclepedia_1229 26154623 Homo sapiens Size-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals Plasma Protein Size exclusion chromatography Extracellular vesicles
527 Vesiclepedia_1076 25104112 Homo sapiens Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. Plasma Protein Differential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Exosomes
528 Vesiclepedia_1073 25104112 Homo sapiens Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. Plasma Protein Differential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Exosomes
529 Vesiclepedia_401 19548909 Homo sapiens Differential stimulation of monocytic cells results in distinct populations of microparticles. Monocytes Protein - Microparticles
530 Vesiclepedia_929 25483805 Gallus gallus Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties Notochord cells Protein Differential centrifugation
Ultracentrifugation
Exosomes
531 Vesiclepedia_896 26100252 Homo sapiens Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts Chronic lymphocytic leukemia cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Exosomes
532 Vesiclepedia_705 28811610 Homo sapiens Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. T cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Microvesicles/Apoptotic bodies
533 Vesiclepedia_89 20424270 Rattus norvegicus Exosomes account for vesicle-mediated transcellular transport of activatable phospholipases and prostaglandins. Basophilic leukemia cells Protein
Lipids
Differential centrifugation
Sucrose density gradient
Exosomes
534 Vesiclepedia_594 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Kidney cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
535 Vesiclepedia_380 18346024 Homo sapiens The proteome of red cell membranes and vesicles during storage in blood bank conditions. Red blood cells Protein - Microvesicles/Nanovesicles
536 Vesiclepedia_116 21505438 Homo sapiens Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells. B cells Protein
miRNA
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
537 Vesiclepedia_21 19837982 Homo sapiens Proteomic and bioinformatic analysis of immunoaffinity-purified exosomes derived from the human colon tumor cell line LIM1215. Colorectal cancer cells Protein Filtration
Ultracentrifugation
Sucrose density gradient
Exosomes
538 Vesiclepedia_113 21557262 Homo sapiens Proteomic identification of exosomal LRG1: A potential urinary biomarker for detecting NSCLC. Urine Protein Differential centrifugation
Ultracentrifugation
Exosomes
539 Vesiclepedia_1074 25104112 Homo sapiens Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. Plasma Protein Differential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Exosomes
540 Vesiclepedia_801 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Embryonic kidney cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
541 Vesiclepedia_805 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types T cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
542 Vesiclepedia_600 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Kidney cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
543 Vesiclepedia_299 12796750 Homo sapiens High levels of circulating endothelial microparticles in patients with acute coronary syndromes Plasma Protein Differential centrifugation
FACS
Microparticles
544 Vesiclepedia_1289 19912576 Homo sapiens HIV Nef is secreted in exosomes and triggers apoptosis in bystander CD4+ T cells. Cervix carcinoma cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
545 Vesiclepedia_800 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Embryonic kidney cells Protein Differential centrifugation Microvesicles
546 Vesiclepedia_1137 23861904 Homo sapiens Exosomal signaling during hypoxia mediates microvascular endothelial cell migration and vasculogenesis. Placental mesenchymal stem cells Protein Differential centrifugation
Ultracentrifugation
Ultrafiltration
Density gradient centrifugation
Exosomes
547 Vesiclepedia_993 24434149 Homo sapiens In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome. Ovarian cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes
548 Vesiclepedia_314 15499615 Homo sapiens Microvesicles derived from activated platelets induce metastasis and angiogenesis in lung cancer Lung cancer cells Protein Differential centrifugation
FACS
Microvesicles
549 Vesiclepedia_627 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Ovarian cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
550 Vesiclepedia_104 21763319 Homo sapiens Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells. Pancreatic adenocarcinoma cells Protein Differential centrifugation
Filtration
Ultrafiltration
Ultracentrifugation
Exosomes
551 Vesiclepedia_598 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Kidney cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
552 Vesiclepedia_28 19109410 Homo sapiens Proteomic and immunologic analyses of brain tumor exosomes. Glioma cells Protein Differential centrifugation
Sucrose density gradient
Exosomes
553 Vesiclepedia_1166 29904572 Bos taurus A subset of extracellular vesicles carries the bulk of microRNAs in commercial dairy cow's milk. Bovine milk Protein
miRNA
Differential centrifugation
Density gradient centrifugation
Extracellular vesicles
554 Vesiclepedia_373 17787032 Escherichia coli Global proteomic profiling of native outer membrane vesicles derived from Escherichia coli. Escherichia coli Protein - Membrane vesicles
555 Vesiclepedia_845 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
556 Vesiclepedia_1269 24218614 Homo sapiens Unexpected gain of function for the scaffolding protein plectin due to mislocalization in pancreatic cancer. Pancreatic adenocarcinoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes
557 Vesiclepedia_847 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
558 Vesiclepedia_143 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells Protein Sucrose density gradient Exosomes
559 Vesiclepedia_843 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
560 Vesiclepedia_258 9126269 Homo sapiens Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations Leukemia cells Protein Differential centrifugation
Sucrose density gradient
Microvesicles
561 Vesiclepedia_1036 29887978 Homo sapiens Evaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing. Serum Protein
miRNA
Exo-spin Extracellular vesicles
562 Vesiclepedia_563 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells Protein Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Microvesicles
563 Vesiclepedia_1022 19665478 Salmo salar CpG-induced secretion of MHCIIbeta and exosomes from salmon (Salmo salar) APCs. Head kidney leukocytes Protein Differential centrifugation
Ultracentrifugation
Exosomes
564 Vesiclepedia_177 19567368 Homo sapiens Proteomics characterization of cell membrane blebs in human retinal pigment epithelium cells Epithelial cells Protein Differential centrifugation Membrane blebs
565 Vesiclepedia_35 19367702 Rattus norvegicus Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes. Hepatocytes Protein Differential centrifugation
Filtration
Sucrose density gradient
Exosomes
566 Vesiclepedia_1031 29887978 Homo sapiens Evaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing. Serum Protein
miRNA
exoEasy columns Extracellular vesicles
567 Vesiclepedia_761 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Exosomes
568 Vesiclepedia_1164 29904572 Bos taurus A subset of extracellular vesicles carries the bulk of microRNAs in commercial dairy cow's milk. Bovine milk Protein
miRNA
Differential centrifugation
Density gradient centrifugation
Extracellular vesicles
569 Vesiclepedia_889 24946052 Homo sapiens Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment Lung cancer cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Extracellular vesicles
570 Vesiclepedia_977 22808001 Homo sapiens Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment. Serum Protein Filtration
ExoQuick
Exosomes
571 Vesiclepedia_823 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Filtration
Ultracentrifugation
Sucrose density gradient
Exosomes
572 Vesiclepedia_251 9396452 Homo sapiens Cell-derived microparticles generated in patients during cardiopulmonary bypass are highly procoagulant Plasma Protein
Lipids
Differential centrifugation Microparticles
573 Vesiclepedia_73 18494037 Mus musculus Difference gel electrophoresis analysis of Ras-transformed fibroblast cell-derived exosomes. Embryonic fibroblasts Protein Differential centrifugation Exosomes
574 Vesiclepedia_379 18346024 Homo sapiens The proteome of red cell membranes and vesicles during storage in blood bank conditions. Red blood cells Protein - Microvesicles/Nanovesicles
575 Vesiclepedia_567 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells Protein Differential centrifugation
Ultracentrifugation
Immunobeads (Igg1 FT)
Extracellular vesicles
576 Vesiclepedia_1225 26154623 Homo sapiens Size-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals Plasma Protein Exo-spin Extracellular vesicles
577 Vesiclepedia_132 19188015 Homo sapiens Systemic presence and tumor-growth promoting effect of ovarian carcinoma released exosomes Ovarian cancer cells Protein
Lipids
Differential centrifugation
Sucrose density gradient
Exosomes
578 Vesiclepedia_849 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
579 Vesiclepedia_136 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells Protein Sucrose density gradient Exosomes
580 Vesiclepedia_937 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. Urine Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
581 Vesiclepedia_835 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Differential centrifugation
Filtration
ExoQuick
Ultracentrifugation
Exosomes
582 Vesiclepedia_1242 25261722 Homo sapiens Inflammatory cytokines, interleukin-1 beta and tumor necrosis factor-alpha, upregulated in glioblastoma multiforme, raise the levels of CRYAB in exosomes secreted by U373 glioma cells. Glioblastoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes
583 Vesiclepedia_168 21859146 Homo sapiens Identification of a conserved glycan signature for microvesicles T cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Microvesicles
584 Vesiclepedia_815 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Differential centrifugation
Filtration
ExoQuick
Ultracentrifugation
Exosomes
585 Vesiclepedia_268 12757771 Homo sapiens Endothelial cells release phenotypically and quantitatively distinct microparticles in activation and apoptosis Endothelial cells Protein Differential centrifugation
FACS
Microparticles
586 Vesiclepedia_228 2942561 Homo sapiens Platelet surface glycoproteins. Studies on resting and activated platelets and platelet membrane microparticles in normal subjects, and observations in patients during adult respiratory distress syndrome and cardiac surgery Serum Protein Differential centrifugation Microparticles
587 Vesiclepedia_146 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells Protein Sucrose density gradient Exosomes
588 Vesiclepedia_1008 23463506 Homo sapiens The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes. T cells Protein Differential centrifugation
Ultracentrifugation
Exosomes
589 Vesiclepedia_854 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
590 Vesiclepedia_542 23935504 Homo sapiens A Novel Role for Pro-Coagulant Microvesicles in the Early Host Defense against Streptococcus pyogenes. Peripheral blood mononucelar cells Protein - Microvesicles
591 Vesiclepedia_426 21386968 Acinetobacter baumannii Acinetobacter baumannii secretes cytotoxic outer membrane protein A via outer membrane vesicles. Acinetobacter baumannii Protein - Membrane vesicles
592 Vesiclepedia_704 28811610 Homo sapiens Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. T cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Microvesicles/Apoptotic bodies
593 Vesiclepedia_51 14975938 Homo sapiens Proteomic analysis of exosomes isolated from human malignant pleural effusions. Malignant pleural effusions Protein Differential centrifugation
Sucrose density gradient
Exosomes
594 Vesiclepedia_12 15478216 Homo sapiens Proteomic analysis of melanoma-derived exosomes by two-dimensional polyacrylamide gel electrophoresis and mass spectrometry. Melanoma cells Protein Filtration
Ultracentrifugation
Sucrose density gradient
Exosomes
595 Vesiclepedia_1252 24939845 Homo sapiens Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein. T cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
596 Vesiclepedia_391 19327352 Bos taurus Anchorage-independent growth of breast carcinoma cells is mediated by serum exosomes. Serum Protein - Exosomes
597 Vesiclepedia_865 22046311 Mus musculus Exosomes from Plasmodium yoelii-infected reticulocytes protect mice from lethal infections Reticulocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
598 Vesiclepedia_1104 24391718 Homo sapiens Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Prostate epithelial cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
599 Vesiclepedia_33 21136642 Mus musculus Oligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons? Oligodendrocytes Protein Differential centrifugation
Sucrose density gradient
Exosomes
600 Vesiclepedia_309 17536014 Homo sapiens Endothelial progenitor cell derived microvesicles activate an angiogenic program in endothelial cells by a horizontal transfer of Mrna Endothelial cells Protein
mRNA
Differential centrifugation
Ultracentrifugation
FACS
Microvesicles
601 Vesiclepedia_691 28170197 Homo sapiens Enhanced Cardioprotection by Human Endometrium Mesenchymal Stem Cells Driven by Exosomal MicroRNA-21 Endometrium-derived mesenchymal stem cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
602 Vesiclepedia_1003 23785420 Bos taurus CD9-positive microvesicles mediate the transfer of molecules to Bovine Spermatozoa during epididymal maturation. Epididymal fluid Protein Differential centrifugation
Ultracentrifugation
Immunoaffinity [CD9]
Microvesicles
603 Vesiclepedia_1186 28326167 Homo sapiens Residual urinary extracellular vesicles in ultracentrifugation supernatants after hydrostatic filtration dialysis enrichment. Urine Protein Hydrostatic filtration dialysis
Differential centrifugation
Ultracentrifugation
Extracellular vesicles
604 Vesiclepedia_631 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Ovarian cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
605 Vesiclepedia_1223 26154623 Homo sapiens Size-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals Plasma Protein Exo-spin Extracellular vesicles
606 Vesiclepedia_50 14582906 Homo sapiens Exosomes with major histocompatibility complex class II and co-stimulatory molecules are present in human BAL fluid. Dendritic cells Protein Differential centrifugation
Immunobeads (EpCAM)
Exosomes
607 Vesiclepedia_1002 24211404 Mus musculus Induction of pulmonary hypertensive changes by extracellular vesicles from monocrotaline-treated mice. Lung tissue Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
608 Vesiclepedia_1268 24218614 Homo sapiens Unexpected gain of function for the scaffolding protein plectin due to mislocalization in pancreatic cancer. Pancreatic adenocarcinoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes
609 Vesiclepedia_573 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells Protein Differential centrifugation
Ultracentrifugation
Immunobeads (CD81 FT)
Extracellular vesicles
610 Vesiclepedia_596 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Kidney cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
611 Vesiclepedia_202 21601655 Homo sapiens Sizing and phenotyping of cellular vesicles using Nanoparticle Tracking Analysis Placenta Protein Differential centrifugation
Ultracentrifugation
Microvesicles
612 Vesiclepedia_154 21966536 Mus musculus Leukocyte- and platelet-derived microvesicle interactions following in vitro and in vivo activation of toll-like receptor 4 by lipopolysaccharide Plasma Protein Differential centrifugation
Filtration
Microvesicles
613 Vesiclepedia_1024 22327366 Homo sapiens Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs. Vascular endothelial cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
614 Vesiclepedia_784 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
615 Vesiclepedia_95 21828046 Rattus norvegicus The proteo-lipidic composition of exosomes changes during reticulocyte maturation. Reticulocytes Protein
Lipids
Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
616 Vesiclepedia_692 28170197 Homo sapiens Enhanced Cardioprotection by Human Endometrium Mesenchymal Stem Cells Driven by Exosomal MicroRNA-21 Adipose-derived mesenchymal stem cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
617 Vesiclepedia_448 22448133 Pseudomonas aeruginosa Vesiculation from Pseudomonas aeruginosa under SOS. Pseudomonas aeruginosa Protein - Membrane vesicles
618 Vesiclepedia_266 18425114 Mus musculus Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells Plasma Protein Differential centrifugation
Ultracentrifugation
Microvesicles
619 Vesiclepedia_1249 24939845 Homo sapiens Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein. Leukemia cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
620 Vesiclepedia_1106 24391718 Homo sapiens Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Prostate epithelial cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
621 Vesiclepedia_814 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Differential centrifugation
Filtration
ExoQuick
Ultracentrifugation
Exosomes
622 Vesiclepedia_1270 24218614 Homo sapiens Unexpected gain of function for the scaffolding protein plectin due to mislocalization in pancreatic cancer. Pancreatic adenocarcinoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes
623 Vesiclepedia_859 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Plasma Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
624 Vesiclepedia_1212 29127410 Homo sapiens Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. Bronchial epithelial cells Protein Ultracentrifugation Extracellular vesicles
625 Vesiclepedia_1096 24976626 Homo sapiens Exosomal transfer from human renal proximal tubule cells to distal tubule and collecting duct cells. Renal proximal tubule cells Protein Differential centrifugation
Ultracentrifugation
Immunoaffinity
Exosomes
626 Vesiclepedia_722 25802036 Homo sapiens Glioblastoma-derived extracellular vesicles modify the phenotype of monocytic cells. Glioblastoma cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
627 Vesiclepedia_760 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
628 Vesiclepedia_1254 24468161 Homo sapiens Molecular characterization of exosome-like vesicles from breast cancer cells. Breast cancer cells Protein
miRNA
Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Extracellular vesicles
629 Vesiclepedia_70 19812188 Rattus norvegicus Immature dendritic cell-derived exosomes rescue septic animals via milk fat globule epidermal growth factor VIII. Dendritic cells Protein Differential centrifugation Exosomes
630 Vesiclepedia_307 16342139 Homo sapiens Proteomic analysis of malignant lymphocyte membrane microparticles using double ionization coverage optimization T cells Protein Differential centrifugation Microparticles
631 Vesiclepedia_983 25367658 Candida albicans Proteomics unravels extracellular vesicles as carriers of classical cytoplasmic proteins in Candida albicans. Candida albicans Protein Differential centrifugation
Ultracentrifugation
Filtration
Extracellular vesicles
632 Vesiclepedia_618 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Melanoma cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
633 Vesiclepedia_680 29148239 Homo sapiens Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. Umblical cord mesenchymal stem cells Protein Differential centrifugation
Ultracentrifugation
Sonication
Filtration
Microvesicles
634 Vesiclepedia_687 29148239 Homo sapiens Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. Umblical cord mesenchymal stem cells Protein Differential centrifugation
Ultracentrifugation
Sonication
Filtration
Microvesicles
635 Vesiclepedia_419 21136642 Mus musculus Oligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons? Oligodendrocytes Protein - Exosomes
636 Vesiclepedia_151 22075275 Homo sapiens Methodology for isolation, identification and characterization of microvesicles in peripheral blood Plasma Protein Differential centrifugation
Filtration
Ultracentrifugation
Microvesicles
637 Vesiclepedia_1094 25065644 Homo sapiens Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells. Duodenal cancer cells Protein Differential centrifugation
Filtration
Ultrafiltration
Exosomes
638 Vesiclepedia_956 27601599 Homo sapiens Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. Breast milk Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Extracellular vesicles
639 Vesiclepedia_783 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
640 Vesiclepedia_718 26148937 Homo sapiens Proteomics profiling of cholangiocarcinoma exosomes: A potential role of oncogenic protein transferring in cancer progression. Cholangiocarcinoma cells Protein Differential centrifugation
Ultracentrifugation
Filtration
Exosomes
641 Vesiclepedia_1006 23463506 Mus musculus The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes. T cells Protein Differential centrifugation
Ultracentrifugation
Exosomes
642 Vesiclepedia_302 1321158 Rattus norvegicus Membrane anchoring of the autoantigen GAD65 to microvesicles in pancreatic beta-cells by palmitoylation in the NH2-terminal domain. Pancreatic cells Protein Differential centrifugation Microvesicles
643 Vesiclepedia_235 10648405 Homo sapiens Cellular origin and procoagulant properties of microparticles in meningococcal sepsis Plasma Protein Differential centrifugation
FACS
Microparticles
644 Vesiclepedia_953 27601599 Homo sapiens Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. Breast milk Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Extracellular vesicles
645 Vesiclepedia_1193 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer. Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
646 Vesiclepedia_715 28811610 Homo sapiens Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. T cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Apoptotic bodies
647 Vesiclepedia_1122 24347249 Homo sapiens Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules. Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
ExoQuick
Exosomes
648 Vesiclepedia_257 9126269 Homo sapiens Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations Leukemia cells Protein Differential centrifugation
Sucrose density gradient
Microvesicles
649 Vesiclepedia_1191 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer. Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
650 Vesiclepedia_959 26196085 Homo sapiens Identification of prostate cancer biomarkers in urinary exosomes. Urine Protein Differential centrifugation
Ultracentrifugation
Filtration
Exosomes
651 Vesiclepedia_911 28687758 Sus scrofa Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers Polarised retinal pigmented epithelial cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
652 Vesiclepedia_422 21138299 Francisella philomiragia Proteomic characterization and functional analysis of outer membrane vesicles of Francisella novicida suggests possible role in virulence and use as a vaccine. Francisella philomiragia Protein - Membrane vesicles
653 Vesiclepedia_19 16302729 Homo sapiens Purification, characterization and biological significance of tumor-derived exosomes. Breast cancer cells Protein Differential centrifugation
Sucrose density gradient
Filtration
Immunobeads(HER2)
Exosomes
654 Vesiclepedia_137 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells Protein Sucrose density gradient Exosomes
655 Vesiclepedia_142 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells Protein Sucrose density gradient Exosomes
656 Vesiclepedia_230 2294986 Homo sapiens Direct detection of activated platelets and platelet-derived microparticles in humans Plasma Protein FACS Microparticles
657 Vesiclepedia_126 - Homo sapiens Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy? Mesenchymal stem cells Protein HPLC Exosomes
658 Vesiclepedia_160 21630462 Homo sapiens Proteomic analysis of microvesicles derived from human colorectal cancer ascites Ascites Protein Differential centrifugation
Sucrose density gradient
OptiPrep density gradient
Microvesicles
659 Vesiclepedia_420 21136987 Helicobacter pylori Proteomic and functional characterization of the outer membrane vesicles from the gastric pathogen Helicobacter pylori. Helicobacter pylori Protein - Membrane vesicles
660 Vesiclepedia_1056 30035390 Mus musculus Arrestin-domain Containing Protein 1 (Arrdc1) Regulates the Protein Cargo and Release of Extracellular Vesicles. Mouse embryonic fibroblasts Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
661 Vesiclepedia_101 21828046 Rattus norvegicus The proteo-lipidic composition of exosomes changes during reticulocyte maturation. Reticulocytes Protein
Lipids
Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
662 Vesiclepedia_900 26100252 Homo sapiens Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts Chronic lymphocytic leukemia cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Exosomes
663 Vesiclepedia_1165 29904572 Bos taurus A subset of extracellular vesicles carries the bulk of microRNAs in commercial dairy cow's milk. Bovine milk Protein
miRNA
Differential centrifugation
Density gradient centrifugation
Extracellular vesicles
664 Vesiclepedia_812 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Differential centrifugation
Filtration
ExoQuick
Ultracentrifugation
Exosomes
665 Vesiclepedia_797 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Embryonic kidney cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
666 Vesiclepedia_185 22116803 Equus caballus Cell-Secreted Vesicles in Equine Ovarian Follicular Fluid Contain miRNAs and Proteins: A Possible New Form of Cell Communication Within the Ovarian Follicle Follicular fluid Protein
miRNA
Differential centrifugation
ExoQuick
Exosomes
667 Vesiclepedia_1224 26154623 Homo sapiens Size-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals Plasma Protein Exo-spin Extracellular vesicles
668 Vesiclepedia_2 3597417 Ovis aries Vesicle formation during reticulocyte maturation. Association of plasma membrane activities with released vesicles (exosomes). Reticulocytes Protein
Lipids
Differential centrifugation Exosomes
669 Vesiclepedia_482 23161513 Homo sapiens Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS. Colorectal cancer cells Protein - Exosomes
670 Vesiclepedia_916 28687758 Sus scrofa Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers Polarised retinal pigmented epithelial cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
671 Vesiclepedia_930 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. Bladder cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
672 Vesiclepedia_262 12805058 Homo sapiens Sickle blood contains tissue factor-positive microparticles derived from endothelial cells and monocytes Plasma Protein
Lipids
Differential centrifugation
Ultracentrifugation
FACS
Microparticles
673 Vesiclepedia_216 21293856 Homo sapiens Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC Breast cancer cells Protein Differential centrifugation
Filtration
Ultrafiltration
Ultracentrifugation
Sucrose density gradient
Exosomes
674 Vesiclepedia_1287 20880880 Homo sapiens Proinflammatory exosomes in bronchoalveolar lavage fluid of patients with sarcoidosis. Bronchoalveolar lavage fluid Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Exosomes
675 Vesiclepedia_124 21235781 Homo sapiens Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages. Breast milk Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
676 Vesiclepedia_1015 22711894 Homo sapiens Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages. Macrophages Protein
Lipids
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
677 Vesiclepedia_589 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Colorectal cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
678 Vesiclepedia_96 21828046 Rattus norvegicus The proteo-lipidic composition of exosomes changes during reticulocyte maturation. Reticulocytes Protein
Lipids
Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
679 Vesiclepedia_997 24392111 Mus musculus Proteomic analysis of C2C12 myoblast and myotube exosome-like vesicles: a new paradigm for myoblast-myotube cross talk? Murine myotubues Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
680 Vesiclepedia_15 17486113 Mus musculus
Homo sapiens
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Mast cells Protein
mRNA
miRNA
Filtration
Ultracentrifugation
Sucrose density gradient
Exosomes
681 Vesiclepedia_238 21293856 Homo sapiens Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC Ascites Protein Differential centrifugation
Filtration
Ultrafiltration
Ultracentrifugation
Sucrose density gradient
Exosomes
682 Vesiclepedia_817 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Differential centrifugation
Filtration
ExoQuick
Ultracentrifugation
Exosomes
683 Vesiclepedia_1107 24391718 Homo sapiens Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Prostate epithelial cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
684 Vesiclepedia_787 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Embryonic kidney cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
685 Vesiclepedia_712 28811610 Homo sapiens Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. T cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Apoptotic bodies
686 Vesiclepedia_848 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
687 Vesiclepedia_672 29953960 Homo sapiens Exosomes derived from calcium oxalate-exposed macrophages enhance IL-8 production from renal cells, neutrophil migration and crystal invasion through extracellular matrix. Macrophages Protein Microfiltration
Differential centrifugation
Ultracentrifugation
Exosomes
688 Vesiclepedia_140 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells Protein Sucrose density gradient Exosomes
689 Vesiclepedia_254 9126269 Homo sapiens Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations Leukemia cells Protein Differential centrifugation
Sucrose density gradient
Microvesicles
690 Vesiclepedia_263 12805058 Homo sapiens Sickle blood contains tissue factor-positive microparticles derived from endothelial cells and monocytes Plasma Protein Differential centrifugation
Ultracentrifugation
FACS
Microparticles
691 Vesiclepedia_1159 20409149 Homo sapiens Transdifferentiated circulating monocytes release exosomes containing 14-3-3 proteins with matrix metalloproteinase-1 stimulating effect for dermal fibroblasts. Keratinocytes Protein Differential centrifugation
Filtration
Ultrafiltration
Ultracentrifugation
Sucrose density gradient
Exosomes
692 Vesiclepedia_883 29955024 Homo sapiens Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells Myeloid leukemia cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
693 Vesiclepedia_45 18589210 Homo sapiens MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer. Serum Protein
miRNA
Ultracentrifugation
Immunobeads (EpCAM)
Exosomes
694 Vesiclepedia_826 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Filtration
Ultracentrifugation
Sucrose density gradient
Exosomes
695 Vesiclepedia_1118 24391718 Homo sapiens Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
696 Vesiclepedia_731 25359493 Homo sapiens Proteomic signatures of extracellular vesicles secreted by nonmineralizing and mineralizing human osteoblasts and stimulation of tumor cell growth. Osteoblasts Protein Differential centrifugation
Ultracentrifugation
Matrix vesicles
697 Vesiclepedia_948 28819550 Mus musculus Effects of storage temperature on airway exosome integrity for diagnostic and functional analyses. Bronchoalveolar lavage fluid Protein Differential centrifugation
Ultracentrifugation
Exosomes
698 Vesiclepedia_1188 28326167 Homo sapiens Residual urinary extracellular vesicles in ultracentrifugation supernatants after hydrostatic filtration dialysis enrichment. Urine Protein Hydrostatic filtration dialysis
Differential centrifugation
Ultracentrifugation
Extracellular vesicles
699 Vesiclepedia_996 24392111 Mus musculus Proteomic analysis of C2C12 myoblast and myotube exosome-like vesicles: a new paradigm for myoblast-myotube cross talk? Murine myoblast Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
700 Vesiclepedia_579 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Breast cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
701 Vesiclepedia_103 21763319 Homo sapiens Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells. Pancreatic adenocarcinoma cells Protein Differential centrifugation
Filtration
Ultrafiltration
Ultracentrifugation
Exosomes
702 Vesiclepedia_469 23029346 Echinostoma caproni Extracellular Vesicles from Parasitic Helminths Contain Specific Excretory/Secretory Proteins and Are Internalized in Intestinal Host Cells. Echinostoma caproni Protein - Exosomes/Extracellular vesicles/Microvesicles
703 Vesiclepedia_767 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
704 Vesiclepedia_613 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Lung cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
705 Vesiclepedia_556 24069378 Homo sapiens Proteome profiling of neuroblastoma-derived exosomes reveal the expression of proteins potentially involved in tumor progression. Neuroblastoma cells Protein - Exosomes/Membrane vesicles
706 Vesiclepedia_29 19109410 Homo sapiens Proteomic and immunologic analyses of brain tumor exosomes. Serum Protein Differential centrifugation
Sucrose density gradient
Exosomes
707 Vesiclepedia_315 15499615 Homo sapiens Microvesicles derived from activated platelets induce metastasis and angiogenesis in lung cancer Lung cancer cells Protein Differential centrifugation
FACS
Microvesicles
708 Vesiclepedia_773 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes Protein Differential centrifugation Apoptotic bodies
709 Vesiclepedia_270 10903724 Homo sapiens Follicular dendritic cells carry MHC class II-expressing microvesicles at their surface Dendritic cells Protein - Microvesicles
710 Vesiclepedia_1228 26154623 Homo sapiens Size-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals Plasma Protein Size exclusion chromatography Extracellular vesicles
711 Vesiclepedia_1075 25104112 Homo sapiens Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. Plasma Protein Differential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Exosomes
712 Vesiclepedia_1167 29907695 Mus musculus Cancer cells copy migratory behavior and exchange signaling networks via extracellular vesicles. Melanoma cells Protein
miRNA
Differential centrifugation
Ultracentrifugation
Extracellular vesicles
713 Vesiclepedia_1009 23185418 Homo sapiens Improved flow cytometric assessment reveals distinct microvesicle (cell-derived microparticle) signatures in joint diseases. Synovial fluid Protein Filtration
Ultracentrifugation
Microvesicles
714 Vesiclepedia_943 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. Urine Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
715 Vesiclepedia_780 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
716 Vesiclepedia_1161 22641613 Homo sapiens Application of systems biology principles to protein biomarker discovery: urinary exosomal proteome in renal transplantation. Urine Protein Differential centrifugation
Ultracentrifugation
Exosomes
717 Vesiclepedia_570 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells Protein Differential centrifugation
Ultracentrifugation
Immunobeads (CD63 PD)
Extracellular vesicles
718 Vesiclepedia_77 20224111 Homo sapiens Proteomics analysis of bladder cancer exosomes. Urine Protein Differential centrifugation
Sucrose density gradient
Exosomes
719 Vesiclepedia_292 10415024 Homo sapiens Activated human T cells release bioactive Fas ligand and APO2 ligand in microvesicles T cells Protein Differential centrifugation
Ultracentrifugation
FACS
Microvesicles
720 Vesiclepedia_1070 29937354 Homo sapiens Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors. Glioblastoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes
721 Vesiclepedia_324 20079801 Mus musculus Microvesicle entry into marrow cells mediates tissue-specific changes in mRNA by direct delivery of mRNA and induction of transcription Lung cells Protein
miRNA
Differential centrifugation
FACS
Microvesicles
722 Vesiclepedia_427 21408115 Edwardsiella tarda Outer membrane vesicles as a candidate vaccine against edwardsiellosis. Edwardsiella tarda Protein - Membrane vesicles
723 Vesiclepedia_727 25359493 Homo sapiens Proteomic signatures of extracellular vesicles secreted by nonmineralizing and mineralizing human osteoblasts and stimulation of tumor cell growth. Osteoblasts Protein Differential centrifugation
Ultracentrifugation
Matrix vesicles
724 Vesiclepedia_926 25483805 Homo sapiens Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties Embryonic kidney cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
725 Vesiclepedia_939 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. Urine Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
726 Vesiclepedia_576 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Breast cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
727 Vesiclepedia_13 15326289 Homo sapiens Identification and proteomic profiling of exosomes in human urine. Urine Protein Ultracentrifugation Exosomes
728 Vesiclepedia_1052 29115712 Mus musculus Proteomic Profiling of Exosomes Secreted by Breast Cancer Cells with Varying Metastatic Potential. Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes
729 Vesiclepedia_694 28842968 Homo sapiens Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles. Colorectal cancer cells Protein Differential centrifugation
Ultracentrifugation
Microvesicles
730 Vesiclepedia_766 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
731 Vesiclepedia_1033 29887978 Homo sapiens Evaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing. Serum Protein
miRNA
qEV size-exclusion column Extracellular vesicles
732 Vesiclepedia_622 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Melanoma cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
733 Vesiclepedia_1251 24939845 Homo sapiens Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein. Leukemia cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
734 Vesiclepedia_1116 24391718 Homo sapiens Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Prostate epithelial cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
735 Vesiclepedia_918 28687758 Sus scrofa Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers Polarised retinal pigmented epithelial cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
736 Vesiclepedia_775 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes Protein Differential centrifugation Microvesicles
737 Vesiclepedia_818 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Differential centrifugation
Filtration
ExoQuick
Ultracentrifugation
Exosomes
738 Vesiclepedia_1105 24391718 Homo sapiens Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Prostate epithelial cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
739 Vesiclepedia_1160 22641613 Homo sapiens Application of systems biology principles to protein biomarker discovery: urinary exosomal proteome in renal transplantation. Urine Protein Differential centrifugation
Ultracentrifugation
Exosomes
740 Vesiclepedia_1029 26378940 Homo sapiens Redefining the Breast Cancer Exosome Proteome by Tandem Mass Tag Quantitative Proteomics and Multivariate Cluster Analysis. Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
741 Vesiclepedia_838 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Differential centrifugation
Filtration
ExoQuick
Ultracentrifugation
Exosomes
742 Vesiclepedia_1171 29881354 Rattus norvegicus Effects of Acute Aerobic Exercise on Rats Serum Extracellular Vesicles Diameter, Concentration and Small RNAs Content. Serum Protein
miRNA
ExoQuick Extracellular vesicles
743 Vesiclepedia_172 21859146 Homo sapiens Identification of a conserved glycan signature for microvesicles Melanoma cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Microvesicles
744 Vesiclepedia_626 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Ovarian cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
745 Vesiclepedia_1275 23489476 Sus scrofa Boar seminal plasma exosomes: effect on sperm function and protein identification by sequencing. Seminal plasma Protein Differential centrifugation
Gel filtration
Ultracentrifugation
Exosomes
746 Vesiclepedia_284 12796750 Homo sapiens High levels of circulating endothelial microparticles in patients with acute coronary syndromes Plasma Protein Differential centrifugation
FACS
Microparticles
747 Vesiclepedia_388 18570454 Homo sapiens Proteomic analysis of exosomes from human neural stem cells by flow field-flow fractionation and nanoflow liquid chromatography-tandem mass spectrometry. Neural stem cells Protein - Exosomes/Membrane vesicles
748 Vesiclepedia_944 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. Urine Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
749 Vesiclepedia_368 16103114 Neisseria meningitidis Biochemical and functional characterization of membrane blebs purified from Neisseria meningitidis serogroup B. Neisseria meningitidis Protein - Membrane vesicles
750 Vesiclepedia_244 22148876 Homo sapiens Proteomic analysis of microvesicles derived from human mesenchymal stem cells Mesenchymal stem cells Protein Differential centrifugation
Ultrafiltration
Ultracentrifugation
Density gradient centrifugation
Microvesicles
751 Vesiclepedia_872 24614226 Ovis aries Extracellular vesicles in luminal fluid of the ovine uterus Uterine luminal fluid Protein Differential centrifugation
Filtration
ExoQuick
Extracellular vesicles
752 Vesiclepedia_793 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Embryonic kidney cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
753 Vesiclepedia_734 25359493 Homo sapiens Proteomic signatures of extracellular vesicles secreted by nonmineralizing and mineralizing human osteoblasts and stimulation of tumor cell growth. Osteoblasts Protein Differential centrifugation
Ultracentrifugation
Matrix vesicles
754 Vesiclepedia_931 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. Urothelial cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
755 Vesiclepedia_927 25483805 Homo sapiens Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties Embryonic kidney cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
756 Vesiclepedia_121 21276792 Homo sapiens Morphologic and proteomic characterization of exosomes released by cultured extravillous trophoblast cells. Trophoblast cells Protein Differential centrifugation
Ultrafiltration
Ultracentrifugation
Density gradient centrifugation
Exosomes
757 Vesiclepedia_1260 24371517 Homo sapiens Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients. Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes
758 Vesiclepedia_985 25287304 Candida albicans Compositional and immunobiological analyses of extracellular vesicles released by Candida albicans. Candida albicans Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
759 Vesiclepedia_397 19413345 Homo sapiens Proteomic analysis of malignant B-cell derived microparticles reveals CD148 as a potentially useful antigenic biomarker for mantle cell lymphoma diagnosis. B cells Protein - Microparticles
760 Vesiclepedia_762 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Exosomes
761 Vesiclepedia_49 14582906 Homo sapiens Exosomes with major histocompatibility complex class II and co-stimulatory molecules are present in human BAL fluid. Bronchoalveolar lavage fluid Protein Differential centrifugation
Immunobeads (EpCAM)
Exosomes
762 Vesiclepedia_74 19381331 Homo sapiens High levels of exosomes expressing CD63 and caveolin-1 in plasma of melanoma patients. Melanoma cells Protein Differential centrifugation Exosomes
763 Vesiclepedia_612 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Lung cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
764 Vesiclepedia_592 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Colorectal cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
765 Vesiclepedia_615 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Lung cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
766 Vesiclepedia_1151 22367951 Acinetobacter baumannii Acinetobacter baumannii outer membrane protein A modulates the biogenesis of outer membrane vesicles. Acinetobacter baumannii Protein Differential centrifugation
Ultrafiltration
Ultracentrifugation
Outer membrane vesicles
767 Vesiclepedia_57 17700640 Homo sapiens CD24 is a marker of exosomes secreted into urine and amniotic fluid. Urine Protein Differential centrifugation
Sucrose density gradient
Exosomes
768 Vesiclepedia_611 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Lung cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
769 Vesiclepedia_247 15741221 Homo sapiens Tissue-factor-bearing microvesicles arise from lipid rafts and fuse with activated platelets to initiate coagulation Plasma Protein Differential centrifugation
Immunobeads (TF)
Microvesicles
770 Vesiclepedia_1055 30035390 Mus musculus Arrestin-domain Containing Protein 1 (Arrdc1) Regulates the Protein Cargo and Release of Extracellular Vesicles. Mouse embryonic fibroblasts Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
771 Vesiclepedia_508 23511837 Homo sapiens Differential protein profiling of renal cell carcinoma urinary exosomes. Urine Protein - Exosomes/Nanovesicles
772 Vesiclepedia_989 25261472 Homo sapiens Complex N-linked glycans serve as a determinant for exosome/microvesicle cargo recruitment. Melanoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes/Microvesicles
773 Vesiclepedia_942 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. Urine Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
774 Vesiclepedia_857 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
775 Vesiclepedia_950 27601599 Homo sapiens Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. Breast milk Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Extracellular vesicles
776 Vesiclepedia_176 21788507 Homo sapiens Hypoxia triggers a proangiogenic pathway involving cancer cell microvesicles and PAR-2-mediated heparin-binding EGF signaling in endothelial cells Glioblastoma cells Protein Differential centrifugation Microvesicles
777 Vesiclepedia_915 28687758 Sus scrofa Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers Polarised retinal pigmented epithelial cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
778 Vesiclepedia_97 21828046 Rattus norvegicus The proteo-lipidic composition of exosomes changes during reticulocyte maturation. Reticulocytes Protein
Lipids
Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
779 Vesiclepedia_105 21763319 Homo sapiens Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells. Pancreatic adenocarcinoma cells Protein Differential centrifugation
Filtration
Ultrafiltration
Ultracentrifugation
Exosomes
780 Vesiclepedia_1034 29887978 Homo sapiens Evaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing. Serum Protein
miRNA
qEV size-exclusion column Extracellular vesicles
781 Vesiclepedia_782 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
782 Vesiclepedia_1190 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer. Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
783 Vesiclepedia_888 24946052 Homo sapiens Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment Lung cancer cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Extracellular vesicles
784 Vesiclepedia_395 19413345 Homo sapiens Proteomic analysis of malignant B-cell derived microparticles reveals CD148 as a potentially useful antigenic biomarker for mantle cell lymphoma diagnosis. B cells Protein - Microparticles
785 Vesiclepedia_739 25157233 Homo sapiens Extravillous trophoblast cells-derived exosomes promote vascular smooth muscle cell migration. Placenta Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
786 Vesiclepedia_759 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
787 Vesiclepedia_468 23000592 Homo sapiens In-depth analysis of the secretome identifies three major independent secretory pathways in differentiating human myoblasts. Neonatal myoblast cells Protein - Microvesicles/Nanovesicles
788 Vesiclepedia_1253 24939845 Homo sapiens Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein. T cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
789 Vesiclepedia_1139 23707955 Bos taurus Prostasomes from four different species are able to produce extracellular adenosine triphosphate (ATP). Seminal plasma Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Prostasomes
790 Vesiclepedia_546 23983189 Homo sapiens Characterization of Multiple Myeloma Vesicles by Label-Free Relative Quantitation. B cells Protein - Exosomes/Extracellular vesicles/Microvesicles
791 Vesiclepedia_264 18425114 Homo sapiens Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells Epidermoid carcinoma cells Protein Differential centrifugation
Ultracentrifugation
Microvesicles
792 Vesiclepedia_806 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types T cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
793 Vesiclepedia_1235 25421927 Heligmosomoides polygyrus Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity. Heligmosomoides polygyrus miRNA
Protein
Filtration
Ultracentrifugation
Exosomes
794 Vesiclepedia_67 19619303 Homo sapiens Claudin-containing exosomes in the peripheral circulation of women with ovarian cancer. Ovarian cancer cells Protein Differential centrifugation
Sucrose density gradient
Exosomes
795 Vesiclepedia_1131 23954818 Homo sapiens Qualitative changes in the proteome of extracellular vesicles accompanying cancer cell transition to mesenchymal state. Squamous carcinoma cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
796 Vesiclepedia_891 24946052 Homo sapiens Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment Lung cancer cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Extracellular vesicles
797 Vesiclepedia_354 24115447 Homo sapiens Comparative proteomics evaluation of plasma exosome isolation techniques and assessment of the stability of exosomes in normal human blood plasma Plasma Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Exosomes
798 Vesiclepedia_92 20124479 Rattus norvegicus Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation. Pancreatic adenocarcinoma cells Protein
mRNA
Differential centrifugation
Sucrose density gradient
Exosomes
799 Vesiclepedia_549 24009881 Homo sapiens Quantitative proteomics of extracellular vesicles derived from human primary and metastatic colorectal cancer cells. Colorectal cancer cells Protein - Exosomes/Extracellular vesicles/Microvesicles/Ectosomes
800 Vesiclepedia_479 23082778 Homo sapiens Comparative and Targeted Proteomic Analyses of Urinary Microparticles from Bladder Cancer and Hernia Patients. Urine Protein - Exosomes/Membrane vesicles
801 Vesiclepedia_478 23082778 Homo sapiens Comparative and Targeted Proteomic Analyses of Urinary Microparticles from Bladder Cancer and Hernia Patients. Urine Protein - Exosomes/Membrane vesicles
802 Vesiclepedia_130 18309083 Mus musculus Ceramide triggers budding of exosome vesicles into multivesicular endosomes Oligodendrocytes Protein
Lipids
Differential centrifugation
Sucrose density gradient
Exosomes
803 Vesiclepedia_217 21293856 Homo sapiens Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC Serum Protein Differential centrifugation
Filtration
Ultrafiltration
Ultracentrifugation
Sucrose density gradient
Exosomes
804 Vesiclepedia_978 22808001 Homo sapiens Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment. Serum Protein Filtration
ExoQuick
Exosomes
805 Vesiclepedia_852 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
806 Vesiclepedia_1208 29127410 Homo sapiens Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. Bronchial epithelial cells Protein Ultrafiltration
Size exclusion chromatography
Extracellular vesicles
807 Vesiclepedia_912 28687758 Sus scrofa Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers Polarised retinal pigmented epithelial cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
808 Vesiclepedia_1231 25503107 Homo sapiens Tumor-derived microvesicles mediate human breast cancer invasion through differentially glycosylated EMMPRIN. Breast cancer cells Protein Ultracentrifugation
Filtration
Density gradient centrifugation
Microvesicles
809 Vesiclepedia_488 23230278 Homo sapiens Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids. Colorectal cancer cells Protein - Exosomes/Extracellular vesicles/Microvesicles
810 Vesiclepedia_877 29955024 Homo sapiens Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells Embryonic kidney cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
811 Vesiclepedia_473 23056467 Homo sapiens Cause or Effect of Arteriogenesis: Compositional Alterations of Microparticles from CAD Patients Undergoing External Counterpulsation Therapy. Plasma Protein - Microparticles
812 Vesiclepedia_220 10694520 Homo sapiens Elevated levels of shed membrane microparticles with procoagulant potential in the peripheral circulating blood of patients with acute coronary syndromes Plasma Protein Immunoaffinity [Annexin-V] Microparticles
813 Vesiclepedia_1284 22345510 Rattus norvegicus Characterization of membrane-shed microvesicles from cytokine-stimulated .-cells using proteomics strategies. Insulinoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes
814 Vesiclepedia_122 21235781 Homo sapiens Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages. Saliva Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
815 Vesiclepedia_650 29188495 Homo sapiens Protein Biomarkers and Neuroproteomics Characterization of Microvesicles/Exosomes from Human Cerebrospinal Fluid Following Traumatic Brain Injury. Cerebrospinal fluid Protein Differential centrifugation
Ultracentrifugation
Sonication
Filtration
Extracellular vesicles
816 Vesiclepedia_651 29188495 Homo sapiens Protein Biomarkers and Neuroproteomics Characterization of Microvesicles/Exosomes from Human Cerebrospinal Fluid Following Traumatic Brain Injury. Cerebrospinal fluid Protein Differential centrifugation
Ultracentrifugation
Sonication
Filtration
Extracellular vesicles
817 Vesiclepedia_750 29988836 Homo sapiens Ultrafiltration and size exclusion chromatography combined with asymmetrical-flow field-flow fractionation for the isolation and characterisation of extracellular vesicles from urine Urine Protein Filtration
Size exclusion chromatography
Extracellular vesicles
818 Vesiclepedia_1291 19912576 Homo sapiens HIV Nef is secreted in exosomes and triggers apoptosis in bystander CD4+ T cells. Lymphoblasts Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
819 Vesiclepedia_789 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Embryonic kidney cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Exosomes
820 Vesiclepedia_1110 24391718 Homo sapiens Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
821 Vesiclepedia_1290 19912576 Homo sapiens HIV Nef is secreted in exosomes and triggers apoptosis in bystander CD4+ T cells. Lymphoblasts Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
822 Vesiclepedia_677 29951053 Mus musculus Immunoregulatory Effects of Myeloid-Derived Suppressor Cell Exosomes in Mouse Model of Autoimmune Alopecia Areata. Dendritic cells Protein Ultracentrifugation
Density gradient centrifugation
Exosomes
823 Vesiclepedia_1044 27770278 Homo sapiens Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease. Glioblastoma cells Protein Differential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Extracellular vesicles
824 Vesiclepedia_26 19109410 Mus musculus Proteomic and immunologic analyses of brain tumor exosomes. Brain cancer cells Protein Differential centrifugation
Sucrose density gradient
Exosomes
825 Vesiclepedia_47 17641064 Homo sapiens Exosomes with immune modulatory features are present in human breast milk. B cells Protein Differential centrifugation
Filtration
Sucrose density gradient
Exosomes
826 Vesiclepedia_5 11145662 Mus musculus Mast cell-dependent B and T lymphocyte activation is mediated by the secretion of immunologically active exosomes. Mast cells Protein Differential centrifugation Exosomes
827 Vesiclepedia_1049 28842968 Homo sapiens Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles. Colorectal cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
828 Vesiclepedia_1145 23173708 Rattus norvegicus Wnt3a induces exosome secretion from primary cultured rat microglia. Primary microglial cells Protein Differential centrifugation
Ultracentrifugation
Exosomes
829 Vesiclepedia_1058 30035390 Mus musculus Arrestin-domain Containing Protein 1 (Arrdc1) Regulates the Protein Cargo and Release of Extracellular Vesicles. Mouse embryonic fibroblasts Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
830 Vesiclepedia_8 12626558 Mus musculus Mast cell-derived exosomes induce phenotypic and functional maturation of dendritic cells and elicit specific immune responses in vivo. B cells Protein Differential centrifugation Exosomes
831 Vesiclepedia_59 17700640 Mus musculus CD24 is a marker of exosomes secreted into urine and amniotic fluid. Amniotic fluid Protein Differential centrifugation
Sucrose density gradient
Exosomes
832 Vesiclepedia_1146 23173708 Rattus norvegicus Wnt3a induces exosome secretion from primary cultured rat microglia. Primary microglial cells Protein Differential centrifugation
Ultracentrifugation
Exosomes
833 Vesiclepedia_139 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells Protein Sucrose density gradient Exosomes
834 Vesiclepedia_1150 22807456 Homo sapiens Quantitative proteomic analysis of exosomes from HIV-1-infected lymphocytic cells. Lymphocytes Protein Differential centrifugation
Ultracentrifugation
Exosomes
835 Vesiclepedia_1221 27872147 Rattus norvegicus Primary Human and Rat .-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity. Insulinoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes
836 Vesiclepedia_723 25802036 Homo sapiens Glioblastoma-derived extracellular vesicles modify the phenotype of monocytic cells. Glioblastoma cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
837 Vesiclepedia_733 25359493 Homo sapiens Proteomic signatures of extracellular vesicles secreted by nonmineralizing and mineralizing human osteoblasts and stimulation of tumor cell growth. Osteoblasts Protein Differential centrifugation
Ultracentrifugation
Matrix vesicles
838 Vesiclepedia_702 28811610 Homo sapiens Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. T cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Apoptotic bodies
839 Vesiclepedia_1051 29115712 Mus musculus Proteomic Profiling of Exosomes Secreted by Breast Cancer Cells with Varying Metastatic Potential. Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes
840 Vesiclepedia_287 12417540 Homo sapiens Elevated numbers of tissue-factor exposing microparticles correlate with components of the metabolic syndrome in uncomplicated type 2 diabetes mellitus Plasma Protein Differential centrifugation
FACS
Microparticles
841 Vesiclepedia_1277 23344851 Rattus norvegicus Urinary exosomes and diabetic nephropathy: a proteomic approach. Urine Protein Ultracentrifugation Exosomes
842 Vesiclepedia_409 20031610 Homo sapiens Proteomics, metabolomics, and immunomics on microparticles derived from human atherosclerotic plaques. Carotid atherosclerotic plaques Protein - Microparticles
843 Vesiclepedia_125 21059916 Homo sapiens Human tumor virus utilizes exosomes for intercellular communication. Nasopharyngeal carcinoma cells Protein Differential centrifugation Exosomes
844 Vesiclepedia_1060 30006486 Homo sapiens The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells. Astrocytoma cells Protein Filtration
Ultracentrifugation
Density gradient centrifugation
Extracellular vesicles
845 Vesiclepedia_253 9126269 Homo sapiens Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations Leukemia cells Protein Differential centrifugation
Sucrose density gradient
Microvesicles
846 Vesiclepedia_1019 21734072 Mus musculus Insulinoma-released exosomes or microparticles are immunostimulatory and can activate autoreactive T cells spontaneously developed in nonobese diabetic mice. Insulinoma cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
847 Vesiclepedia_1093 25065644 Homo sapiens Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells. Duodenal cancer cells Protein Differential centrifugation
Filtration
Ultrafiltration
Exosomes
848 Vesiclepedia_1217 27872147 Rattus norvegicus Primary Human and Rat .-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity. Islets Protein Differential centrifugation
Ultracentrifugation
Exosomes
849 Vesiclepedia_779 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
850 Vesiclepedia_141 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells Protein Sucrose density gradient Exosomes
851 Vesiclepedia_972 22808001 Homo sapiens Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment. Serum Protein Filtration
ExoQuick
Exosomes
852 Vesiclepedia_856 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
853 Vesiclepedia_681 29148239 Homo sapiens Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. Umblical cord mesenchymal stem cells Protein Differential centrifugation
Ultracentrifugation
Sonication
Filtration
Microvesicles
854 Vesiclepedia_1239 25329303 Homo sapiens Rapid isolation of extracellular vesicles from cell culture and biological fluids using a synthetic peptide with specific affinity for heat shock proteins. Urine Protein Vn96 peptide precipitation Extracellular vesicles
855 Vesiclepedia_906 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer Urothelial cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
856 Vesiclepedia_543 23977379 Listeria monocytogenes Transcription Factor σ(B) Plays an Important Role in the Production of Extracellular Membrane-Derived Vesicles in Listeria monocytogenes. Listeria monocytogenes Protein - Membrane vesicles
857 Vesiclepedia_1087 25065644 Homo sapiens Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells. Duodenal cancer cells Protein Differential centrifugation
Filtration
Ultrafiltration
Exosomes
858 Vesiclepedia_375 18095356 Gallus gallus Proteome analysis of matrix vesicles isolated from femurs of chicken embryo. 17-day-old embryo leg bone Protein - Matrix vesicles
859 Vesiclepedia_966 25844599 Homo sapiens Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. Serum Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
860 Vesiclepedia_46 17641064 Homo sapiens Exosomes with immune modulatory features are present in human breast milk. Breast milk Protein Differential centrifugation
Filtration
Sucrose density gradient
Exosomes
861 Vesiclepedia_507 23511837 Homo sapiens Differential protein profiling of renal cell carcinoma urinary exosomes. Urine Protein - Exosomes/Nanovesicles
862 Vesiclepedia_717 26148937 Homo sapiens Proteomics profiling of cholangiocarcinoma exosomes: A potential role of oncogenic protein transferring in cancer progression. Cholangiocytes Protein Differential centrifugation
Ultracentrifugation
Filtration
Exosomes
863 Vesiclepedia_882 29955024 Homo sapiens Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells Myeloid leukemia cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
864 Vesiclepedia_1084 25104112 Homo sapiens Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. Plasma Protein Differential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Exosomes
865 Vesiclepedia_744 29988836 Homo sapiens Ultrafiltration and size exclusion chromatography combined with asymmetrical-flow field-flow fractionation for the isolation and characterisation of extracellular vesicles from urine Urine Protein Filtration
Size exclusion chromatography
Extracellular vesicles
866 Vesiclepedia_1090 25065644 Homo sapiens Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells. Duodenal cancer cells Protein Differential centrifugation
Filtration
Ultrafiltration
Exosomes
867 Vesiclepedia_1243 25261722 Homo sapiens Inflammatory cytokines, interleukin-1 beta and tumor necrosis factor-alpha, upregulated in glioblastoma multiforme, raise the levels of CRYAB in exosomes secreted by U373 glioma cells. Glioblastoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes
868 Vesiclepedia_221 9918520 Homo sapiens Shed membrane microparticles with procoagulant potential in human atherosclerotic plaques: a role for apoptosis in plaque thrombogenicity Atherosclerotic plaques Protein
Lipids
Differential centrifugation
Immunoaffinity [Annexin-V]
Apoptotic bodies
869 Vesiclepedia_862 25776846 Homo sapiens Human thymic epithelial primary cells produce exosomes carrying tissue-restricted antigens Epithelial cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
870 Vesiclepedia_16 9685355 Homo sapiens Selective enrichment of tetraspan proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B-lymphocytes. B cells Protein Differential centrifugation
Sucrose density gradient
Exosomes
871 Vesiclepedia_584 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Brain cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
872 Vesiclepedia_1266 24310399 Homo sapiens Extracellular vesicles modulate the glioblastoma microenvironment via a tumor suppression signaling network directed by miR-1. Glioblastoma cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles
873 Vesiclepedia_298 12796750 Homo sapiens High levels of circulating endothelial microparticles in patients with acute coronary syndromes Plasma Protein Differential centrifugation
FACS
Microparticles
874 Vesiclepedia_163 21901833 Drosophila melanogaster Proteomics analyses of microvesicles released by Drosophila Kc167 and S2 cells Hematocytes Protein Differential centrifugation
Sucrose density gradient
Ultracentrifugation
Microvesicles
875 Vesiclepedia_788 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Embryonic kidney cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Exosomes
876 Vesiclepedia_682 29148239 Homo sapiens Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. Umblical cord mesenchymal stem cells Protein Differential centrifugation
Ultracentrifugation
Sonication
Filtration
Microvesicles
877 Vesiclepedia_120 21362503 Homo sapiens Protein profile of exosomes from trabecular meshwork cells. Aqueous humor Protein Differential centrifugation
Sucrose density gradient
Exosomes
878 Vesiclepedia_604 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Leukemia cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
879 Vesiclepedia_234 10648405 Homo sapiens Cellular origin and procoagulant properties of microparticles in meningococcal sepsis Plasma Protein Differential centrifugation
FACS
Microparticles
880 Vesiclepedia_492 23333927 Homo sapiens Characterization and proteomic analysis of ovarian cancer-derived exosomes. Ovarian cancer cells Protein - Exosomes
881 Vesiclepedia_965 25844599 Homo sapiens Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. Serum Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
882 Vesiclepedia_1153 22057275 Homo sapiens Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease. Neuroblastoma cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
883 Vesiclepedia_1014 22711894 Homo sapiens Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages. Macrophages Protein
Lipids
Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
884 Vesiclepedia_749 29988836 Homo sapiens Ultrafiltration and size exclusion chromatography combined with asymmetrical-flow field-flow fractionation for the isolation and characterisation of extracellular vesicles from urine Urine Protein Filtration
Size exclusion chromatography
Extracellular vesicles
885 Vesiclepedia_442 22288420 Paracoccidioides brasiliensis Vesicle and vesicle-free extracellular proteome of Paracoccidioides brasiliensis: comparative analysis with other pathogenic fungi. Paracoccidioides brasiliensis Protein - Extracellular vesicles
886 Vesiclepedia_349 22285593 Homo sapiens Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes. Colorectal cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Exosomes
887 Vesiclepedia_347 22285593 Homo sapiens Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes. Colorectal cancer cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
888 Vesiclepedia_269 12757771 Homo sapiens Endothelial cells release phenotypically and quantitatively distinct microparticles in activation and apoptosis Endothelial cells Protein Differential centrifugation
FACS
Microparticles
889 Vesiclepedia_614 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Lung cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
890 Vesiclepedia_446 22428779 Klebsiella pneumoniae Klebsiella pneumoniae secretes outer membrane vesicles that induce the innate immune response. Klebsiella pneumoniae Protein - Membrane vesicles
891 Vesiclepedia_982 25458527 Homo sapiens Benchtop isolation and characterization of functional exosomes by sequential filtration Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes
892 Vesiclepedia_227 2942561 Homo sapiens Platelet surface glycoproteins. Studies on resting and activated platelets and platelet membrane microparticles in normal subjects, and observations in patients during adult respiratory distress syndrome and cardiac surgery Plasma Protein Differential centrifugation Microparticles
893 Vesiclepedia_400 19548894 Acinetobacter baumannii Proteome analysis of outer membrane vesicles from a clinical Acinetobacter baumannii isolate. Acinetobacter baumannii Protein - Membrane vesicles
894 Vesiclepedia_1280 22345510 Rattus norvegicus Characterization of membrane-shed microvesicles from cytokine-stimulated .-cells using proteomics strategies. Insulinoma cells Protein Differential centrifugation Microparticles
895 Vesiclepedia_1072 29937354 Homo sapiens Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors. Glioblastoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes
896 Vesiclepedia_837 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Differential centrifugation
Filtration
ExoQuick
Ultracentrifugation
Exosomes
897 Vesiclepedia_203 19011622 Homo sapiens Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers Glioblastoma cells Protein
miRNA
mRNA
Differential centrifugation
Ultracentrifugation
Filtration
Microvesicles
898 Vesiclepedia_1097 24513287 Mus musculus Lipid synthesis is promoted by hypoxic adipocyte-derived exosomes in 3T3-L1 cells. adipocytes Protein Differential centrifugation
Ultracentrifugation
Filtration
Exosomes
899 Vesiclepedia_574 27601599 Homo sapiens Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components Breast milk Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Extracellular vesicles
900 Vesiclepedia_581 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Brain cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
901 Vesiclepedia_9 12626558 Mus musculus Mast cell-derived exosomes induce phenotypic and functional maturation of dendritic cells and elicit specific immune responses in vivo. Macrophages Protein Differential centrifugation Exosomes
902 Vesiclepedia_1207 29127410 Homo sapiens Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. Bronchial epithelial cells Protein Ultrafiltration
Size exclusion chromatography
Extracellular vesicles
903 Vesiclepedia_377 18346024 Homo sapiens The proteome of red cell membranes and vesicles during storage in blood bank conditions. Red blood cells Protein - Microvesicles/Nanovesicles
904 Vesiclepedia_1138 23707955 Homo sapiens Prostasomes from four different species are able to produce extracellular adenosine triphosphate (ATP). Seminal plasma Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Prostasomes
905 Vesiclepedia_517 23585443 Homo sapiens Proteome profiling of exosomes derived from human primary and metastatic colorectal cells reveal differential expression of key metastatic factors and signal transduction components. Colorectal cancer cells Protein - Exosomes/Membrane vesicles
906 Vesiclepedia_941 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. Urine Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
907 Vesiclepedia_1121 24347249 Homo sapiens Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules. Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
ExoQuick
Exosomes
908 Vesiclepedia_725 25471207 Homo sapiens Intraluminal proteome and peptidome of human urinary extracellular vesicles. Urine Protein Differential centrifugation
Hydrostatic filtration dialysis
Ultrafiltration
Exosomes
909 Vesiclepedia_133 19188015 Homo sapiens Systemic presence and tumor-growth promoting effect of ovarian carcinoma released exosomes Ovarian cancer cells Protein
Lipids
Differential centrifugation
Sucrose density gradient
Exosomes
910 Vesiclepedia_599 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Kidney cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
911 Vesiclepedia_808 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types T cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
912 Vesiclepedia_909 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer Transitional carcinoma cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
913 Vesiclepedia_1113 24391718 Homo sapiens Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
914 Vesiclepedia_853 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
915 Vesiclepedia_803 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types T cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
916 Vesiclepedia_597 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Kidney cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
917 Vesiclepedia_487 23230278 Homo sapiens Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids. Colorectal cancer cells Protein - Exosomes/Extracellular vesicles/Microvesicles
918 Vesiclepedia_565 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells Protein Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Exosomes
919 Vesiclepedia_1214 29127410 Homo sapiens Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. Bronchial epithelial cells Protein Ultracentrifugation Extracellular vesicles
920 Vesiclepedia_127 21828046 Rattus norvegicus Proteolipidic Composition of Exosomes Changes during Reticulocyte Maturation Reticulocytes Protein
Lipids
Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
921 Vesiclepedia_846 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
922 Vesiclepedia_954 27601599 Homo sapiens Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. Breast milk Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Extracellular vesicles
923 Vesiclepedia_603 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Leukemia cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
924 Vesiclepedia_1152 22057275 Homo sapiens Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease. Neuroblastoma cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
925 Vesiclepedia_738 25157233 Homo sapiens Extravillous trophoblast cells-derived exosomes promote vascular smooth muscle cell migration. Placenta choriocarcinoma cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
926 Vesiclepedia_447 22444574 Homo sapiens Proteomic analysis of microvesicles in human saliva by gel electrophoresis with liquid chromatography-mass spectrometry. Saliva Protein - Exosomes/Microvesicles
927 Vesiclepedia_63 19056867 Homo sapiens Large-scale proteomics and phosphoproteomics of urinary exosomes. Urine Protein Differential centrifugation Exosomes
928 Vesiclepedia_1255 24468161 Homo sapiens Molecular characterization of exosome-like vesicles from breast cancer cells. Breast cancer cells Protein
miRNA
Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Extracellular vesicles
929 Vesiclepedia_737 25220352 Mus musculus Surface functionalization of exosomes using click chemistry. Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
930 Vesiclepedia_1000 24079734 Mus musculus Immunostimulatory activity of murine keratinocyte-derived exosomes. Keratinocytes Protein Differential centrifugation
Ultracentrifugation
Exosomes
931 Vesiclepedia_831 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Differential centrifugation
Filtration
ExoQuick
Ultracentrifugation
Exosomes
932 Vesiclepedia_698 28811610 Homo sapiens Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. T cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Exosomes
933 Vesiclepedia_907 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer Transitional papilloma cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
934 Vesiclepedia_902 26100252 Homo sapiens Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts Chronic lymphocytic leukemia cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Exosomes
935 Vesiclepedia_595 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Kidney cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
936 Vesiclepedia_634 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Prostate cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
937 Vesiclepedia_305 17478559 Rattus norvegicus Identification and characterization of microvesicles secreted by 3T3-L1 adipocytes: redox- and hormone-dependent induction of milk fat globule-epidermal growth 8-associated microvesicles Adipocytes Protein Differential centrifugation Microvesicles
938 Vesiclepedia_868 24614226 Ovis aries Extracellular vesicles in luminal fluid of the ovine uterus Uterine luminal fluid Protein Differential centrifugation
Filtration
ExoQuick
Extracellular vesicles
939 Vesiclepedia_53 14975938 Homo sapiens Proteomic analysis of exosomes isolated from human malignant pleural effusions. Malignant pleural effusions Protein Differential centrifugation
Sucrose density gradient
Exosomes
940 Vesiclepedia_924 25483805 Homo sapiens Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties Embryonic kidney cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
941 Vesiclepedia_708 28811610 Homo sapiens Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. T cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Microvesicles
942 Vesiclepedia_1127 24295599 Mus musculus Exosomes from myeloid-derived suppressor cells carry biologically active proteins. Myeloid-derived suppressor cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
943 Vesiclepedia_607 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Leukemia cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
944 Vesiclepedia_1089 25065644 Homo sapiens Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells. Duodenal cancer cells Protein Differential centrifugation
Filtration
Ultrafiltration
Exosomes
945 Vesiclepedia_887 25102470 Homo sapiens Examination of the specificity of tumor cell derived exosomes with tumor cells in vitro Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
946 Vesiclepedia_93 20124479 Rattus norvegicus Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation. Pancreatic adenocarcinoma cells Protein
mRNA
Differential centrifugation
Sucrose density gradient
Exosomes
947 Vesiclepedia_936 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. Urine Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
948 Vesiclepedia_461 22848702 Homo sapiens Medulloblastoma exosome proteomics yield functional roles for extracellular vesicles. Medulloblastoma cells Protein - Exosomes/Membrane vesicles/Extracellular vesicles
949 Vesiclepedia_807 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types T cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
950 Vesiclepedia_523 23658846 Mus musculus Immunomodulatory impact of leishmania-induced macrophage exosomes: a comparative proteomic and functional analysis. Macrophages Protein - Exosomes
951 Vesiclepedia_1206 29127410 Homo sapiens Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. Bronchial epithelial cells Protein Ultrafiltration
Size exclusion chromatography
Extracellular vesicles
952 Vesiclepedia_3 10545503 Mus musculus Molecular characterization of dendritic cell-derived exosomes. Selective accumulation of the heat shock protein hsc73. Dendritic cells Protein Differential centrifugation
Sucrose density gradient
Exosomes
953 Vesiclepedia_621 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Melanoma cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
954 Vesiclepedia_1081 25104112 Homo sapiens Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. Plasma Protein Differential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Exosomes
955 Vesiclepedia_709 28811610 Homo sapiens Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. T cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Apoptotic bodies
956 Vesiclepedia_1265 24310399 Homo sapiens Extracellular vesicles modulate the glioblastoma microenvironment via a tumor suppression signaling network directed by miR-1. Glioblastoma cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Extracellular vesicles
957 Vesiclepedia_878 29955024 Homo sapiens Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells Embryonic kidney cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
958 Vesiclepedia_880 29955024 Homo sapiens Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells Myeloid leukemia cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
959 Vesiclepedia_654 28290293 Bos taurus Comparative proteomic analysis of milk-derived exosomes in human and bovine colostrum and mature milk samples by iTRAQ-coupled LC-MS/MS. Bovine milk Protein Differential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Exosomes
960 Vesiclepedia_276 12021310 Homo sapiens Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles Melanoma cells Protein Differential centrifugation
Ultracentrifugation
Microvesicles
961 Vesiclepedia_970 25844599 Homo sapiens Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. Serum Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
962 Vesiclepedia_696 28842968 Homo sapiens Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles. Colorectal cancer cells Protein Differential centrifugation
Ultracentrifugation
Microvesicles
963 Vesiclepedia_870 24614226 Ovis aries Extracellular vesicles in luminal fluid of the ovine uterus Uterine luminal fluid Protein Differential centrifugation
Filtration
ExoQuick
Extracellular vesicles
964 Vesiclepedia_729 25359493 Homo sapiens Proteomic signatures of extracellular vesicles secreted by nonmineralizing and mineralizing human osteoblasts and stimulation of tumor cell growth. Osteoblasts Protein Differential centrifugation
Ultracentrifugation
Matrix vesicles
965 Vesiclepedia_1080 25104112 Homo sapiens Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. Plasma Protein Differential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Exosomes
966 Vesiclepedia_1099 24513287 Mus musculus Lipid synthesis is promoted by hypoxic adipocyte-derived exosomes in 3T3-L1 cells. adipocytes Protein Differential centrifugation
Ultracentrifugation
Filtration
Exosomes
967 Vesiclepedia_1246 25167841 Homo sapiens Antibody-coupled monolithic silica microtips for highthroughput molecular profiling of circulating exosomes. Serum Protein CD9 antibody to Mass Spectrometric Immunoassay monolith pipette tips Exosomes
968 Vesiclepedia_840 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
969 Vesiclepedia_1241 25329303 Homo sapiens Rapid isolation of extracellular vesicles from cell culture and biological fluids using a synthetic peptide with specific affinity for heat shock proteins. Urine Protein Vn96 peptide precipitation Extracellular vesicles
970 Vesiclepedia_484 23214914 Trypanosoma cruzi Proteomic analysis of Trypanosoma cruzi secretome: characterization of two populations of extracellular vesicles and soluble proteins. Epimastigotes Protein - Exosomes/Extracellular vesicles/Ectosomes
971 Vesiclepedia_310 22148876 Homo sapiens Proteomic analysis of microvesicles derived from human mesenchymal stem cells Mesenchymal stem cells Protein Differential centrifugation
Ultrafiltration
Ultracentrifugation
Density gradient centrifugation
Microvesicles
972 Vesiclepedia_303 19930720 Homo sapiens Colorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells Colorectal cancer cells Protein
mRNA
Differential centrifugation
Ultrafiltration
OptiPrep density gradient
Microvesicles
973 Vesiclepedia_586 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Brain cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
974 Vesiclepedia_312 15499615 Homo sapiens Microvesicles derived from activated platelets induce metastasis and angiogenesis in lung cancer Lung cancer cells Protein Differential centrifugation
FACS
Microvesicles
975 Vesiclepedia_255 9126269 Homo sapiens Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations Burkitt's lymphoma Protein Differential centrifugation
Sucrose density gradient
Microvesicles
976 Vesiclepedia_1134 23861904 Homo sapiens Exosomal signaling during hypoxia mediates microvascular endothelial cell migration and vasculogenesis. Placental mesenchymal stem cells Protein Differential centrifugation
Ultracentrifugation
Ultrafiltration
Density gradient centrifugation
Exosomes
977 Vesiclepedia_1043 27770278 Homo sapiens Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease. Glioblastoma cells Protein Differential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Extracellular vesicles
978 Vesiclepedia_559 26098775 Citrus Limon L. Citrus limon-derived nanovesicles inhibit cancer cell proliferation and suppress CML xenograft growth by inducing TRAIL-mediated cell death Lemon juice Protein Differential centrifugation
Ultracentrifugation
Microvesicles
979 Vesiclepedia_241 16192427 Homo sapiens Circulating endothelial microparticles are associated with vascular dysfunction in patients with end-stage renal failure Plasma Protein Differential centrifugation
FACS
Microparticles
980 Vesiclepedia_587 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Colorectal cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
981 Vesiclepedia_222 12514112 Homo sapiens Intravascular tissue factor initiates coagulation via circulating microvesicles and platelets Plasma Protein Differential centrifugation
FACS
Microvesicles
982 Vesiclepedia_1187 28326167 Homo sapiens Residual urinary extracellular vesicles in ultracentrifugation supernatants after hydrostatic filtration dialysis enrichment. Urine Protein Hydrostatic filtration dialysis
Differential centrifugation
Ultracentrifugation
Extracellular vesicles
983 Vesiclepedia_973 22808001 Homo sapiens Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment. Serum Protein Filtration
ExoQuick
Exosomes
984 Vesiclepedia_754 29963269 Homo sapiens Mining of potential microRNAs with clinical correlation - regulation of syndecan-1 expression by miR-122-5p altered mobility of breast cancer cells and possible correlation with liver injury Hepatoma cells Protein Total Exosome Isolation Kit
Differential centrifugation
Exosomes
985 Vesiclepedia_881 29955024 Homo sapiens Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells Myeloid leukemia cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
986 Vesiclepedia_437 22106071 Homo sapiens Proteomic analysis of urine exosomes by multidimensional protein identification technology (MudPIT). Urine Protein - Exosomes/Membrane vesicles
987 Vesiclepedia_914 28687758 Sus scrofa Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers Polarised retinal pigmented epithelial cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
988 Vesiclepedia_623 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Melanoma cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
989 Vesiclepedia_14 16081791 Mus musculus Proteomic analysis of microglia-derived exosomes: metabolic role of the aminopeptidase CD13 in neuropeptide catabolism. Microglia Protein Differential centrifugation
Sucrose density gradient
Exosomes
990 Vesiclepedia_1172 29881354 Rattus norvegicus Effects of Acute Aerobic Exercise on Rats Serum Extracellular Vesicles Diameter, Concentration and Small RNAs Content. Serum Protein
miRNA
ExoQuick Extracellular vesicles
991 Vesiclepedia_98 21828046 Rattus norvegicus The proteo-lipidic composition of exosomes changes during reticulocyte maturation. Reticulocytes Protein
Lipids
Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
992 Vesiclepedia_551 24009886 Homo sapiens Cellular stress conditions are reflected in the protein and RNA content of endothelial cell-derived exosomes. Endothelial cells Protein - Exosomes/Extracellular vesicles
993 Vesiclepedia_106 21763319 Homo sapiens Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells. Pancreatic adenocarcinoma cells Protein Differential centrifugation
Filtration
Ultrafiltration
Ultracentrifugation
Exosomes
994 Vesiclepedia_735 25285581 Mus musculus Ubiquitinated proteins in exosomes secreted by myeloid-derived suppressor cells. Myeloid-derived suppressor cells Protein Differential centrifugation
Ultracentrifugation
Exosomes
995 Vesiclepedia_537 23818640 Homo sapiens Modulation of B-cell exosome proteins by gamma herpesvirus infection. B cells Protein - Exosomes/Microvesicles/Oncosomes/Microparticles
996 Vesiclepedia_606 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Leukemia cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
997 Vesiclepedia_816 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Differential centrifugation
Filtration
ExoQuick
Ultracentrifugation
Exosomes
998 Vesiclepedia_770 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
999 Vesiclepedia_1189 28326167 Homo sapiens Residual urinary extracellular vesicles in ultracentrifugation supernatants after hydrostatic filtration dialysis enrichment. Urine Protein Hydrostatic filtration dialysis
Differential centrifugation
Ultracentrifugation
Extracellular vesicles
1000 Vesiclepedia_908 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer Transitional carcinoma cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
1001 Vesiclepedia_311 22148876 Homo sapiens Proteomic analysis of microvesicles derived from human mesenchymal stem cells Mesenchymal stem cells Protein Differential centrifugation
Ultrafiltration
Ultracentrifugation
Density gradient centrifugation
Microvesicles
1002 Vesiclepedia_1232 25475747 Homo sapiens Identification of Biomarkers for PKD1 Using Urinary Exosomes Urine Protein Ultracentrifugation
Density gradient centrifugation
Extracellular vesicles
1003 Vesiclepedia_286 12417540 Homo sapiens Elevated numbers of tissue-factor exposing microparticles correlate with components of the metabolic syndrome in uncomplicated type 2 diabetes mellitus Plasma Protein Differential centrifugation
FACS
Microparticles
1004 Vesiclepedia_706 28811610 Homo sapiens Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. T cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Microvesicles/Apoptotic bodies
1005 Vesiclepedia_237 21293856 Homo sapiens Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC Melanoma cells Protein Differential centrifugation
Filtration
Ultrafiltration
Ultracentrifugation
Sucrose density gradient
Exosomes
1006 Vesiclepedia_90 21828046 Rattus norvegicus The proteo-lipidic composition of exosomes changes during reticulocyte maturation. Reticulocytes Protein
Lipids
Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
1007 Vesiclepedia_841 28881726 Homo sapiens Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
1008 Vesiclepedia_162 21901833 Drosophila melanogaster Proteomics analyses of microvesicles released by Drosophila Kc167 and S2 cells Hematocytes Protein
PTM Ubiquitination
Differential centrifugation
Sucrose density gradient
Ultracentrifugation
Microvesicles
1009 Vesiclepedia_192 21635979 Mus musculus Proteomic characterization of thymocyte-derived microvesicles and apoptotic bodies in BALB/c mice Thymus Protein Differential centrifugation
Filtration
Apoptotic bodies
1010 Vesiclepedia_243 22149170 Homo sapiens The Protein Interaction Network of Extracellular Vesicles Derived from Human Colorectal Cancer Cells Colorectal cancer cells Protein Differential centrifugation
Ultrafiltration
Ultracentrifugation
Density gradient centrifugation
Extracellular vesicles
1011 Vesiclepedia_582 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Brain cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
1012 Vesiclepedia_445 22418980 Homo sapiens A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes. Urine Protein - Exosomes
1013 Vesiclepedia_1086 25065644 Homo sapiens Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells. Duodenal cancer cells Protein Differential centrifugation
Filtration
Ultrafiltration
Exosomes
1014 Vesiclepedia_378 18346024 Homo sapiens The proteome of red cell membranes and vesicles during storage in blood bank conditions. Red blood cells Protein - Microvesicles/Nanovesicles
1015 Vesiclepedia_1286 20880880 Homo sapiens Proinflammatory exosomes in bronchoalveolar lavage fluid of patients with sarcoidosis. Bronchoalveolar lavage fluid Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Exosomes
1016 Vesiclepedia_331 19627513 Homo sapiens Exosomes from human saliva as a source of microRNA biomarkers Saliva Protein
miRNA
Differential centrifugation
Ultracentrifugation
Exosomes
1017 Vesiclepedia_716 26317203 Homo sapiens Progression of Osteosarcoma from a Non-Metastatic to a Metastatic Phenotype Is Causally Associated with Activation of an Autocrine and Paracrine uPA Axis. Osteosarcoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes
1018 Vesiclepedia_938 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer. Urine Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
1019 Vesiclepedia_145 22723089 Homo sapiens Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Prostate cancer cells Protein Sucrose density gradient Exosomes
1020 Vesiclepedia_55 12147373 Homo sapiens Malignant effusions and immunogenic tumour-derived exosomes. Malignant pleural effusions Protein Differential centrifugation
Sucrose density gradient
Exosomes
1021 Vesiclepedia_652 28290293 Homo sapiens Comparative proteomic analysis of milk-derived exosomes in human and bovine colostrum and mature milk samples by iTRAQ-coupled LC-MS/MS. Breast milk Protein Differential centrifugation
Ultracentrifugation
Filtration
Density gradient centrifugation
Exosomes
1022 Vesiclepedia_799 29953723 Homo sapiens Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Embryonic kidney cells Protein Differential centrifugation Microvesicles
1023 Vesiclepedia_975 22808001 Homo sapiens Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment. Serum Protein Filtration
ExoQuick
Exosomes
1024 Vesiclepedia_316 18472965 Homo sapiens Cathepsin B mediates the pH-dependent proinvasive activity of tumor-shed microvesicles Ovarian cancer cells Protein Differential centrifugation Microvesicles
1025 Vesiclepedia_1037 29887978 Homo sapiens Evaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing. Serum Protein
miRNA
miRCURY Exosome Isolation Kit Extracellular vesicles
1026 Vesiclepedia_602 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Leukemia cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
1027 Vesiclepedia_736 25285581 Mus musculus Ubiquitinated proteins in exosomes secreted by myeloid-derived suppressor cells. Myeloid-derived suppressor cells Protein Differential centrifugation
Ultracentrifugation
Exosomes
1028 Vesiclepedia_195 21668449 Mus musculus SV31 is a Zn2+-binding synaptic vesicle protein Pheochromocytoma cells Protein Differential centrifugation
Sucrose density gradient
Large dense core vesicles
1029 Vesiclepedia_785 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Epithelial cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
1030 Vesiclepedia_1020 21734072 Mus musculus Insulinoma-released exosomes or microparticles are immunostimulatory and can activate autoreactive T cells spontaneously developed in nonobese diabetic mice. Insulinoma cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
1031 Vesiclepedia_1276 23344851 Rattus norvegicus Urinary exosomes and diabetic nephropathy: a proteomic approach. Urine Protein Ultracentrifugation Exosomes
1032 Vesiclepedia_684 29148239 Homo sapiens Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. Umblical cord mesenchymal stem cells Protein Differential centrifugation
Ultracentrifugation
Sonication
Filtration
Microvesicles
1033 Vesiclepedia_432 21751344 Pseudomonas aeruginosa Proteomic analysis of outer membrane vesicles derived from Pseudomonas aeruginosa. Pseudomonas aeruginosa Protein - Exosomes/Membrane vesicles
1034 Vesiclepedia_1007 23463506 Mus musculus The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes. T cells Protein Differential centrifugation
Ultracentrifugation
Exosomes
1035 Vesiclepedia_1048 28725021 Bos taurus Bovine milk-derived exosomes from colostrum are enriched with proteins implicated in immune response and growth. Bovine milk Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
1036 Vesiclepedia_828 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Filtration
Ultracentrifugation
Sucrose density gradient
Exosomes
1037 Vesiclepedia_1123 24347249 Homo sapiens Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules. Prostate cancer cells Protein Differential centrifugation
Ultracentrifugation
ExoQuick
Exosomes
1038 Vesiclepedia_610 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Lung cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
1039 Vesiclepedia_501 23410224 Neisseria meningitidis Quantitative proteomics reveals distinct differences in the protein content of outer membrane vesicle vaccines. Neisseria meningitidis Protein - Membrane vesicles
1040 Vesiclepedia_1222 26272980 Homo sapiens Proteomic Profiling of Detergent Resistant Membranes (Lipid Rafts) of Prostasomes Seminal plasma Protein Ultracentrifugation
Density gradient centrifugation
Prostasomes
1041 Vesiclepedia_521 23645497 Canis lupus familiaris Oncogenic H-Ras reprograms Madin-Darby canine kidney (MDCK) cell-derived exosomal proteins following epithelial-mesenchymal transition. Kidney cells Protein - Exosomes/Extracellular vesicles
1042 Vesiclepedia_679 29951053 Mus musculus Immunoregulatory Effects of Myeloid-Derived Suppressor Cell Exosomes in Mouse Model of Autoimmune Alopecia Areata. Myeloid-derived suppressor cells Protein Ultracentrifugation
Density gradient centrifugation
Exosomes
1043 Vesiclepedia_201 21606166 Homo sapiens Blast-derived microvesicles in sera from patients with acute myeloid leukemia suppress natural killer cell function via membrane-associated transforming growth factor-beta2 Serum Protein Size exclusion chromatography
Ultracentrifugation
Microvesicles
1044 Vesiclepedia_385 18563738 Homo sapiens Comparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles. Endothelial cells Protein - Microparticles
1045 Vesiclepedia_894 24946052 Homo sapiens Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment Lung cancer cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Extracellular vesicles
1046 Vesiclepedia_1285 21871517 Burkholderia pseudomallei A naturally derived outer-membrane vesicle vaccine protects against lethal pulmonary Burkholderia pseudomallei infection. Burkholderia pseudomallei Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Outer membrane vesicles
1047 Vesiclepedia_1279 22345510 Rattus norvegicus Characterization of membrane-shed microvesicles from cytokine-stimulated .-cells using proteomics strategies. Insulinoma cells Protein Differential centrifugation Microparticles
1048 Vesiclepedia_683 29148239 Homo sapiens Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. Umblical cord mesenchymal stem cells Protein Differential centrifugation
Ultracentrifugation
Sonication
Filtration
Microvesicles
1049 Vesiclepedia_609 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Lung cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
1050 Vesiclepedia_280 15499615 Homo sapiens Microvesicles derived from activated platelets induce metastasis and angiogenesis in lung cancer Lung cancer cells Protein
mRNA
Differential centrifugation
FACS
Microvesicles
1051 Vesiclepedia_1088 25065644 Homo sapiens Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells. Duodenal cancer cells Protein Differential centrifugation
Filtration
Ultrafiltration
Exosomes
1052 Vesiclepedia_920 28687758 Sus scrofa Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers Polarised retinal pigmented epithelial cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Extracellular vesicles
1053 Vesiclepedia_348 22285593 Homo sapiens Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes. Colorectal cancer cells Protein Differential centrifugation
Filtration
Immunoaffinity (EpCAM)
Ultracentrifugation
Exosomes
1054 Vesiclepedia_246 18425114 Homo sapiens Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells Glioblastoma cells Protein Differential centrifugation
Ultracentrifugation
Microvesicles
1055 Vesiclepedia_1227 26154623 Homo sapiens Size-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals Plasma Protein Size exclusion chromatography Extracellular vesicles
1056 Vesiclepedia_1173 29881354 Rattus norvegicus Effects of Acute Aerobic Exercise on Rats Serum Extracellular Vesicles Diameter, Concentration and Small RNAs Content. Serum Protein
miRNA
ExoQuick Extracellular vesicles
1057 Vesiclepedia_1059 30006486 Homo sapiens The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells. Astrocytoma cells Protein Filtration
Ultracentrifugation
Density gradient centrifugation
Extracellular vesicles
1058 Vesiclepedia_1065 29963299 Homo sapiens Enrichment of extracellular vesicles from human synovial fluid using size exclusion chromatography. Synovial fluid Protein Size exclusion chromatography Extracellular vesicles
1059 Vesiclepedia_822 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Filtration
Ultracentrifugation
Sucrose density gradient
Exosomes
1060 Vesiclepedia_434 22014850 Rattus norvegicus Proteomics of microparticles after experimental pulmonary embolism. Plasma Protein - Microparticles
1061 Vesiclepedia_730 25359493 Homo sapiens Proteomic signatures of extracellular vesicles secreted by nonmineralizing and mineralizing human osteoblasts and stimulation of tumor cell growth. Osteoblasts Protein Differential centrifugation
Ultracentrifugation
Matrix vesicles
1062 Vesiclepedia_1141 23454749 Homo sapiens BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression. Bone marrow mesenchymal stromal cells Protein Differential centrifugation
Ultracentrifugation
Filtration
ExoQuick
Exosomes
1063 Vesiclepedia_713 28811610 Homo sapiens Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. T cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Density gradient centrifugation
Exosomes
1064 Vesiclepedia_1233 25469510 Homo sapiens GAIP interacting protein C-terminus regulates autophagy and exosome biogenesis of pancreatic cancer through metabolic pathways. Pancreatic cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes
1065 Vesiclepedia_398 19530224 Homo sapiens Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes. Keratinocytes Protein - Exosomes
1066 Vesiclepedia_1135 23861904 Homo sapiens Exosomal signaling during hypoxia mediates microvascular endothelial cell migration and vasculogenesis. Placental mesenchymal stem cells Protein Differential centrifugation
Ultracentrifugation
Ultrafiltration
Density gradient centrifugation
Exosomes
1067 Vesiclepedia_493 23333927 Homo sapiens Characterization and proteomic analysis of ovarian cancer-derived exosomes. Ovarian cancer cells Protein - Exosomes
1068 Vesiclepedia_721 26148937 Homo sapiens Proteomics profiling of cholangiocarcinoma exosomes: A potential role of oncogenic protein transferring in cancer progression. Cholangiocarcinoma cells Protein Differential centrifugation
Ultracentrifugation
Filtration
Exosomes
1069 Vesiclepedia_23 11231627 Mus musculus Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming. Breast cancer cells Protein Differential centrifugation
Sucrose density gradient
Exosomes
1070 Vesiclepedia_988 25261472 Homo sapiens Complex N-linked glycans serve as a determinant for exosome/microvesicle cargo recruitment. Melanoma cells Protein Differential centrifugation
Ultracentrifugation
Exosomes/Microvesicles
1071 Vesiclepedia_1169 29907695 Mus musculus Cancer cells copy migratory behavior and exchange signaling networks via extracellular vesicles. Melanoma cells Protein
miRNA
Differential centrifugation
Ultracentrifugation
Extracellular vesicles
1072 Vesiclepedia_214 21364924 Homo sapiens Thermal- and oxidative stress causes enhanced release of NKG2D ligand-bearing immunosuppressive exosomes in leukemia/lymphoma T and B cells T cells Protein Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Exosomes
1073 Vesiclepedia_383 18373357 Homo sapiens Isolation and identification of potential urinary microparticle biomarkers of bladder cancer. Urine Protein - Microparticles
1074 Vesiclepedia_413 20535238 Rattus norvegicus Candidate biomarkers in exosome-like vesicles purified from rat and mouse urine samples. Urine Protein - Exosomes
1075 Vesiclepedia_885 29955024 Homo sapiens Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells Myeloid leukemia cells Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
1076 Vesiclepedia_905 29207636 Homo sapiens Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer Bladder cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
1077 Vesiclepedia_1054 29115712 Mus musculus Proteomic Profiling of Exosomes Secreted by Breast Cancer Cells with Varying Metastatic Potential. Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Exosomes
1078 Vesiclepedia_159 21630462 Homo sapiens Proteomic analysis of microvesicles derived from human colorectal cancer ascites Ascites Protein Differential centrifugation
Sucrose density gradient
OptiPrep density gradient
Microvesicles
1079 Vesiclepedia_271 10903724 Homo sapiens Follicular dendritic cells carry MHC class II-expressing microvesicles at their surface B cells Protein Differential centrifugation Exosomes
1080 Vesiclepedia_372 17096383 Mus musculus Analysis of the extracellular matrix vesicle proteome in mineralizing osteoblasts. Osteoblasts Protein - Matrix vesicles
1081 Vesiclepedia_386 18563738 Homo sapiens Comparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles. Endothelial cells Protein - Microparticles
1082 Vesiclepedia_297 12796750 Homo sapiens High levels of circulating endothelial microparticles in patients with acute coronary syndromes Plasma Protein Differential centrifugation
FACS
Microparticles
1083 Vesiclepedia_110 21601258 Homo sapiens Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage. Ascites Protein
miRNA
Differential centrifugation
Sucrose density gradient
Exosomes
1084 Vesiclepedia_1028 26378940 Homo sapiens Redefining the Breast Cancer Exosome Proteome by Tandem Mass Tag Quantitative Proteomics and Multivariate Cluster Analysis. Breast cancer cells Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
1085 Vesiclepedia_225 10393703 Homo sapiens In vitro generation of endothelial microparticles and possible prothrombotic activity in patients with lupus anticoagulant Plasma Protein Differential centrifugation Microparticles
1086 Vesiclepedia_769 29953723 Salmo salar Stimulation of exosome release by extracellular DNA is conserved across multiple cell types Leukocytes Protein Differential centrifugation
Filtration
Ultracentrifugation
Exosomes
1087 Vesiclepedia_1273 24058411 Homo sapiens Osteoprotegerin in exosome-like vesicles from human cultured tubular cells and urine. Urine Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
1088 Vesiclepedia_625 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Melanoma cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
1089 Vesiclepedia_186 22116803 Equus caballus Cell-Secreted Vesicles in Equine Ovarian Follicular Fluid Contain miRNAs and Proteins: A Possible New Form of Cell Communication Within the Ovarian Follicle Follicular fluid Protein
miRNA
Differential centrifugation
Ultracentrifugation
Microvesicles
1090 Vesiclepedia_428 21515422 Homo sapiens Proteomic characterization of biogenesis and functions of matrix vesicles released from mineralizing human osteoblast-like cells. Osteosarcoma cells Protein - Matrix vesicles
1091 Vesiclepedia_1117 24391718 Homo sapiens Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Prostate epithelial cells Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
1092 Vesiclepedia_1046 28725021 Bos taurus Bovine milk-derived exosomes from colostrum are enriched with proteins implicated in immune response and growth. Bovine milk Protein Differential centrifugation
Ultracentrifugation
Density gradient centrifugation
Exosomes
1093 Vesiclepedia_678 29951053 Mus musculus Immunoregulatory Effects of Myeloid-Derived Suppressor Cell Exosomes in Mouse Model of Autoimmune Alopecia Areata. Myeloid-derived suppressor cells Protein Ultracentrifugation
Density gradient centrifugation
Exosomes
1094 Vesiclepedia_367 12746840 Homo sapiens Proteomic analysis of human prostasomes. Seminal fluid Protein - Prostasomes
1095 Vesiclepedia_390 19158352 Homo sapiens Characterization of PKD protein-positive exosome-like vesicles. Urine Protein - Exosomes/Membrane particles
1096 Vesiclepedia_833 23376832 Rattus norvegicus Cardiac myocyte exosomes: stability, HSP60, and proteomics Cardiomyocytes Protein Differential centrifugation
Filtration
ExoQuick
Ultracentrifugation
Exosomes
1097 Vesiclepedia_593 27894104 Homo sapiens Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers. Colorectal cancer cells Protein Differential centrifugation
Polymer-based precipitation
Ultracentrifugation
Extracellular vesicles
1098 Vesiclepedia_1281 22345510 Rattus norvegicus Characterization of membrane-shed microvesicles from cytokine-stimulated .-cells using proteomics strategies. Insulinoma cells Protein Differential centrifugation Microparticles
1099 Vesiclepedia_294 2071604 Homo sapiens Evidence that agonist-induced activation of calpain causes the shedding of procoagulant-containing microvesicles from the membrane of aggregating platelets Platelets Protein Differential centrifugation
Filtration
Microvesicles
1100 Vesiclepedia_675 29951053 Mus musculus Immunoregulatory Effects of Myeloid-Derived Suppressor Cell Exosomes in Mouse Model of Autoimmune Alopecia Areata. Myeloid-derived suppressor cells Protein Ultracentrifugation
Density gradient centrifugation
Exosomes
1101 Vesiclepedia_1057 30035390 Mus musculus Arrestin-domain Containing Protein 1 (Arrdc1) Regulates the Protein Cargo and Release of Extracellular Vesicles. Mouse embryonic fibroblasts Protein Differential centrifugation
Ultracentrifugation
Extracellular vesicles
1102 Vesiclepedia_252 9126269 Homo sapiens Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations T cells Protein Differential centrifugation
Sucrose density gradient
Microvesicles
1103 Vesiclepedia_685 29148239 Homo sapiens Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. Umblical cord mesenchymal stem cells Protein Differential centrifugation
Ultracentrifugation
Sonication
Filtration
Microvesicles
1104 Vesiclepedia_564 26858453 Homo sapiens Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Dendritic cells Protein Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Exosomes
1105 Vesiclepedia_449 22448133 Pseudomonas aeruginosa Vesiculation from Pseudomonas aeruginosa under SOS. Pseudomonas aeruginosa Protein - Membrane vesicles
1106 Vesiclepedia_686 29148239 Homo sapiens Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants. Umblical cord mesenchymal stem cells Protein Differential centrifugation
Ultracentrifugation
Sonication
Filtration
Microvesicles