Browse results for content type: protein

	Vesiclepedia ID	PubMed ID	Species	Experiment description	Sample	Identifications	Isolation methods	Vesicle type
1	Vesiclepedia_1261	24371517	Homo sapiens	Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
2	Vesiclepedia_1119	24391718	Homo sapiens	Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
3	Vesiclepedia_1101	24513287	Mus musculus	Lipid synthesis is promoted by hypoxic adipocyte-derived exosomes in 3T3-L1 cells.	Serum	Protein	Differential centrifugation Ultracentrifugation Filtration	Exosomes
4	Vesiclepedia_1114	24391718	Homo sapiens	Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
5	Vesiclepedia_608	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Lung cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
6	Vesiclepedia_171	21859146	Homo sapiens	Identification of a conserved glycan signature for microvesicles	Colorectal cancer cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Microvesicles
7	Vesiclepedia_48	17641064	Homo sapiens	Exosomes with immune modulatory features are present in human breast milk.	Breast milk	Protein	Differential centrifugation Filtration Sucrose density gradient	Exosomes
8	Vesiclepedia_1283	22345510	Rattus norvegicus	Characterization of membrane-shed microvesicles from cytokine-stimulated .-cells using proteomics strategies.	Insulinoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
9	Vesiclepedia_933	29207636	Homo sapiens	Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer.	Bladder cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
10	Vesiclepedia_1210	29127410	Homo sapiens	Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies.	Bronchial epithelial cells	Protein	Ultrafiltration Size exclusion chromatography	Extracellular vesicles
11	Vesiclepedia_1170	29907695	Mus musculus	Cancer cells copy migratory behavior and exchange signaling networks via extracellular vesicles.	Melanoma cells	Protein miRNA	Differential centrifugation Ultracentrifugation	Extracellular vesicles
12	Vesiclepedia_1111	24391718	Homo sapiens	Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
13	Vesiclepedia_580	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Brain cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
14	Vesiclepedia_94	21828046	Rattus norvegicus	The proteo-lipidic composition of exosomes changes during reticulocyte maturation.	Reticulocytes	Protein Lipids	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
15	Vesiclepedia_1001	24079734	Mus musculus	Immunostimulatory activity of murine keratinocyte-derived exosomes.	Keratinocytes	Protein	Differential centrifugation Ultracentrifugation	Exosomes
16	Vesiclepedia_957	27601599	Homo sapiens	Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components.	Breast milk	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
17	Vesiclepedia_1021	20332430	Homo sapiens	Proteomic analysis of prostate cancer metastasis-derived prostasomes.	Skeletal tissue	Protein	Differential centrifugation Ultracentrifugation	Prostasomes
18	Vesiclepedia_20	17956143	Homo sapiens	Proteomic analysis of microvesicles derived from human colorectal cancer cells.	Colorectal cancer cells	Protein	Differential centrifugation Sucrose density gradient Diafiltration	Exosomes
19	Vesiclepedia_1005	23463506	Homo sapiens	The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes.	T cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
20	Vesiclepedia_196	21668449	Mus musculus	SV31 is a Zn2+-binding synaptic vesicle protein	Pheochromocytoma cells	Protein	Differential centrifugation Sucrose density gradient	Large dense core vesicles
21	Vesiclepedia_211	21368175	Homo sapiens	Cancer cell-derived microvesicles induce transformation by transferring tissue transglutaminase and fibronectin to recipient cells	Glioma cells	Protein	Differential centrifugation Filtration	Microvesicles
22	Vesiclepedia_1100	24513287	Mus musculus	Lipid synthesis is promoted by hypoxic adipocyte-derived exosomes in 3T3-L1 cells.	adipocytes	Protein	Differential centrifugation Ultracentrifugation Filtration	Exosomes
23	Vesiclepedia_781	29953723	Salmo salar	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Leukocytes	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
24	Vesiclepedia_946	29207636	Homo sapiens	Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer.	Urine	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
25	Vesiclepedia_40	15908444	Homo sapiens	Exosomal-like vesicles are present in human blood plasma.	Plasma	Protein	Differential centrifugation Filtration Sucrose density gradient	Exosomes
26	Vesiclepedia_633	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Prostate cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
27	Vesiclepedia_714	28811610	Homo sapiens	Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA.	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Microvesicles
28	Vesiclepedia_624	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Melanoma cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
29	Vesiclepedia_1257	24400796	Homo sapiens	Exosomal proteins in the aqueous humor as novel biomarkers in patients with neovascular age-related macular degeneration.	Retinal pigment epithelial cells	Protein	ExoQuick	Exosomes
30	Vesiclepedia_1220	27872147	Rattus norvegicus	Primary Human and Rat .-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity.	Insulinoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
31	Vesiclepedia_790	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Embryonic kidney cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
32	Vesiclepedia_1026	22327366	Homo sapiens	Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs.	Vascular endothelial cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
33	Vesiclepedia_703	28811610	Homo sapiens	Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA.	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Apoptotic bodies
34	Vesiclepedia_403	19548909	Homo sapiens	Differential stimulation of monocytic cells results in distinct populations of microparticles.	Monocytes	Protein	-	Microparticles
35	Vesiclepedia_1237	25421927	Heligmosomoides polygyrus	Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity.	Heligmosomoides polygyrus	miRNA Protein	Filtration Ultracentrifugation	Exosomes
36	Vesiclepedia_404	19548909	Homo sapiens	Differential stimulation of monocytic cells results in distinct populations of microparticles.	Monocytes	Protein	-	Microparticles
37	Vesiclepedia_4	11487543	Homo sapiens	Intestinal epithelial cells secrete exosome-like vesicles.	Epithelial cells	Protein	Differential centrifugation Sucrose density gradient	Exosomes
38	Vesiclepedia_1108	24391718	Homo sapiens	Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.	Prostate epithelial cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
39	Vesiclepedia_676	29951053	Mus musculus	Immunoregulatory Effects of Myeloid-Derived Suppressor Cell Exosomes in Mouse Model of Autoimmune Alopecia Areata.	Myeloid-derived suppressor cells	Protein	Ultracentrifugation Density gradient centrifugation	Exosomes
40	Vesiclepedia_245	9126269	Homo sapiens	Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations	T cells	Protein mRNA	Differential centrifugation Sucrose density gradient	Microvesicles
41	Vesiclepedia_183	21741384	Homo sapiens	A filtration-based protocol to isolate human plasma membrane-derived vesicles and exosomes from blood plasma	Plasma	Protein	Differential centrifugation Filtration	Microvesicles
42	Vesiclepedia_971	22808001	Homo sapiens	Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment.	Serum	Protein	Filtration ExoQuick	Exosomes
43	Vesiclepedia_903	25053844	Homo sapiens	Activity-associated miRNA are packaged in Map1b-enriched exosomes released from depolarized neurons	Neuroblastoma cells	Protein	Differential centrifugation Ultracentrifugation Filtration	Exosomes
44	Vesiclepedia_1215	27872147	Rattus norvegicus	Primary Human and Rat .-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity.	Islets	Protein	Differential centrifugation Ultracentrifugation	Exosomes
45	Vesiclepedia_832	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Differential centrifugation Filtration ExoQuick Ultracentrifugation	Exosomes
46	Vesiclepedia_313	15499615	Homo sapiens	Microvesicles derived from activated platelets induce metastasis and angiogenesis in lung cancer	Lung cancer cells	Protein	Differential centrifugation FACS	Microvesicles
47	Vesiclepedia_470	23029346	Fasciola hepatica	Extracellular Vesicles from Parasitic Helminths Contain Specific Excretory/Secretory Proteins and Are Internalized in Intestinal Host Cells.	Fasciola hepatica	Protein	-	Exosomes/Extracellular vesicles/Microvesicles
48	Vesiclepedia_1035	29887978	Homo sapiens	Evaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing.	Serum	Protein miRNA	Exo-spin	Extracellular vesicles
49	Vesiclepedia_1013	22711894	Homo sapiens	Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages.	Macrophages	Protein Lipids	Differential centrifugation Filtration Ultracentrifugation	Exosomes
50	Vesiclepedia_282	19234131	Homo sapiens	Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR	Lung cancer cells	Protein	Differential centrifugation	Microvesicles
51	Vesiclepedia_671	29953960	Homo sapiens	Exosomes derived from calcium oxalate-exposed macrophages enhance IL-8 production from renal cells, neutrophil migration and crystal invasion through extracellular matrix.	Macrophages	Protein	Microfiltration Differential centrifugation Ultracentrifugation	Exosomes
52	Vesiclepedia_697	28842968	Homo sapiens	Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles.	Colorectal cancer cells	Protein	Differential centrifugation Ultracentrifugation	Microvesicles
53	Vesiclepedia_583	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Brain cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
54	Vesiclepedia_605	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Leukemia cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
55	Vesiclepedia_940	29207636	Homo sapiens	Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer.	Urine	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
56	Vesiclepedia_1303	-	Saccharomyces cerevisiae	Extracellular vesicles secreted by Saccharomyces cerevisiae are involved in cell wall remodelling	Saccharomyces cerevisiae	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
57	Vesiclepedia_986	25261472	Homo sapiens	Complex N-linked glycans serve as a determinant for exosome/microvesicle cargo recruitment.	Melanoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes/Microvesicles
58	Vesiclepedia_653	28290293	Homo sapiens	Comparative proteomic analysis of milk-derived exosomes in human and bovine colostrum and mature milk samples by iTRAQ-coupled LC-MS/MS.	Breast milk	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Exosomes
59	Vesiclepedia_844	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
60	Vesiclepedia_399	19530224	Homo sapiens	Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes.	Keratinocytes	Protein	-	Exosomes
61	Vesiclepedia_527	23660474	Homo sapiens	Heterogeneity in neutrophil microparticles reveals distinct proteome and functional properties.	Neutrophils	Protein	-	Microparticles
62	Vesiclepedia_503	23459212	Bos taurus	Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.	Bovine milk	Protein	-	Exosomes
63	Vesiclepedia_824	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Filtration Ultracentrifugation Sucrose density gradient	Exosomes
64	Vesiclepedia_1042	27770278	Homo sapiens	Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease.	Glioblastoma cells	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Extracellular vesicles
65	Vesiclepedia_700	28811610	Homo sapiens	Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA.	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Microvesicles
66	Vesiclepedia_1040	27770278	Homo sapiens	Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease.	Glioblastoma cells	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Extracellular vesicles
67	Vesiclepedia_550	24009881	Homo sapiens	Quantitative proteomics of extracellular vesicles derived from human primary and metastatic colorectal cancer cells.	Colorectal cancer cells	Protein	-	Exosomes/Extracellular vesicles/Microvesicles/Ectosomes
68	Vesiclepedia_407	19834908	Staphylococcus aureus	Gram-positive bacteria produce membrane vesicles: proteomics-based characterization of Staphylococcus aureus-derived membrane vesicles.	Staphylococcus aureus	Protein	-	Membrane vesicles
69	Vesiclepedia_922	25483805	Homo sapiens	Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties	Embryonic kidney cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
70	Vesiclepedia_861	25776846	Homo sapiens	Human thymic epithelial primary cells produce exosomes carrying tissue-restricted antigens	Epithelial cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
71	Vesiclepedia_895	24946052	Homo sapiens	Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment	Lung cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
72	Vesiclepedia_200	21606166	Homo sapiens	Blast-derived microvesicles in sera from patients with acute myeloid leukemia suppress natural killer cell function via membrane-associated transforming growth factor-beta1	Serum	Protein	Size exclusion chromatography Ultracentrifugation	Microvesicles
73	Vesiclepedia_138	22723089	Homo sapiens	Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes.	Prostate cancer cells	Protein	Sucrose density gradient	Exosomes
74	Vesiclepedia_480	23161513	Homo sapiens	Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.	Colorectal cancer cells	Protein	-	Exosomes
75	Vesiclepedia_842	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
76	Vesiclepedia_1120	24347249	Homo sapiens	Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation ExoQuick	Exosomes
77	Vesiclepedia_720	26148937	Homo sapiens	Proteomics profiling of cholangiocarcinoma exosomes: A potential role of oncogenic protein transferring in cancer progression.	Cholangiocytes	Protein	Differential centrifugation Ultracentrifugation Filtration	Exosomes
78	Vesiclepedia_213	21372807	Rattus norvegicus	Upregulation of lipid synthesis in small rat adipocytes by microvesicle-associated CD73 from large adipocytes	Adipocytes	Protein	Differential centrifugation	Microvesicles
79	Vesiclepedia_998	24355714	Homo sapiens	Proteomic analysis and immune properties of exosomes released by macrophages infected with Mycobacterium avium.	Leukemia cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
80	Vesiclepedia_381	18346024	Homo sapiens	The proteome of red cell membranes and vesicles during storage in blood bank conditions.	Red blood cells	Protein	-	Microvesicles/Nanovesicles
81	Vesiclepedia_1011	23185418	Homo sapiens	Improved flow cytometric assessment reveals distinct microvesicle (cell-derived microparticle) signatures in joint diseases.	Synovial fluid	Protein	Filtration Ultracentrifugation	Microvesicles
82	Vesiclepedia_981	25458527	Homo sapiens	Benchtop isolation and characterization of functional exosomes by sequential filtration	Breast cancer cells	Protein	Sequential filtration	Exosomes
83	Vesiclepedia_1310	-	Saccharomyces cerevisiae	Extracellular vesicles secreted by Saccharomyces cerevisiae are involved in cell wall remodelling	Saccharomyces cerevisiae	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
84	Vesiclepedia_275	12021310	Homo sapiens	Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles	Melanoma cells	Protein	Differential centrifugation Ultracentrifugation	Microvesicles
85	Vesiclepedia_153	22022598	Homo sapiens	Syncytiotrophoblast microvesicles released from pre-eclampsia placentae exhibit increased tissue factor activity	Placenta	Protein	Differential centrifugation	Microvesicles
86	Vesiclepedia_158	21630462	Homo sapiens	Proteomic analysis of microvesicles derived from human colorectal cancer ascites	Ascites	Protein	Differential centrifugation Sucrose density gradient OptiPrep density gradient	Microvesicles
87	Vesiclepedia_990	25261472	Homo sapiens	Complex N-linked glycans serve as a determinant for exosome/microvesicle cargo recruitment.	Melanoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes/Microvesicles
88	Vesiclepedia_1236	25421927	Heligmosomoides polygyrus	Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity.	Heligmosomoides polygyrus	miRNA Protein	Filtration Ultracentrifugation	Exosomes
89	Vesiclepedia_306	16342139	Homo sapiens	Proteomic analysis of malignant lymphocyte membrane microparticles using double ionization coverage optimization	T cells	Protein	Differential centrifugation	Microparticles
90	Vesiclepedia_1018	22399603	Homo sapiens	Proteomic analysis of exosome-like vesicles derived from breast cancer cells.	Breast cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
91	Vesiclepedia_591	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Colorectal cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
92	Vesiclepedia_18	11907077	Homo sapiens	TCR activation of human T cells induces the production of exosomes bearing the TCR/CD3/zeta complex.	T cells	Protein	Filtration Ultracentrifugation	Exosomes
93	Vesiclepedia_296	12796750	Homo sapiens	High levels of circulating endothelial microparticles in patients with acute coronary syndromes	Plasma	Protein	Differential centrifugation FACS	Microparticles
94	Vesiclepedia_969	25844599	Homo sapiens	Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.	Serum	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
95	Vesiclepedia_742	28524762	Rattus norvegicus	Exosomes promote restoration after an experimental animal model of intracerebral hemorrhage	Mesenchymal stem cells	Protein	miRCURY Exosome Isolation Kit	Exosomes
96	Vesiclepedia_152	22064971	Homo sapiens	Oxidized low-density lipoprotein-dependent platelet-derived microvesicles trigger procoagulant effects and amplify oxidative stress	Platelets	Protein	Differential centrifugation	Microvesicles
97	Vesiclepedia_917	28687758	Sus scrofa	Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers	Polarised retinal pigmented epithelial cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
98	Vesiclepedia_72	19801663	Homo sapiens	Microenvironmental pH is a key factor for exosome traffic in tumor cells.	Melanoma cells	Protein Lipids	Differential centrifugation	Exosomes
99	Vesiclepedia_945	29207636	Homo sapiens	Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer.	Urine	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
100	Vesiclepedia_184	21672581	Rattus norvegicus	Oxygen-glucose deprivation increases the enzymatic activity and the microvesicle-mediated release of ectonucleotidases in the cells composing the blood-brain barrier	Astrocytes	Protein	Differential centrifugation	Microvesicles
101	Vesiclepedia_24	11231627	Homo sapiens	Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming.	Melanoma cells	Protein	Differential centrifugation Sucrose density gradient	Exosomes
102	Vesiclepedia_1147	23173708	Rattus norvegicus	Wnt3a induces exosome secretion from primary cultured rat microglia.	Primary microglial cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
103	Vesiclepedia_1	6307529	Ovis aries	Fate of the transferrin receptor during maturation of sheep reticulocytes in vitro: selective externalization of the receptor.	Reticulocytes	Protein	-	Exosomes
104	Vesiclepedia_879	29955024	Homo sapiens	Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells	Myeloid leukemia cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
105	Vesiclepedia_402	19548909	Homo sapiens	Differential stimulation of monocytic cells results in distinct populations of microparticles.	Monocytes	Protein	-	Microparticles
106	Vesiclepedia_1130	23954818	Homo sapiens	Qualitative changes in the proteome of extracellular vesicles accompanying cancer cell transition to mesenchymal state.	Squamous carcinoma cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
107	Vesiclepedia_300	19234131	Homo sapiens	Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR	Epidermoid carcinoma cells	Protein	Differential centrifugation	Microvesicles
108	Vesiclepedia_81	20458337	Homo sapiens	MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 3	B cells	Protein	Differential centrifugation Sucrose density gradient Immunobeads (MHC Class II)	Exosomes
109	Vesiclepedia_335	20976003	Homo sapiens	Selective release of microRNA species from normal and malignant mammary epithelial cells	Breast cancer cells	Protein miRNA	Differential centrifugation Filtration	Exosomes
110	Vesiclepedia_471	23035643	Drosophila melanogaster	Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.	Drosophila S2 cells	Protein	-	Exosomes
111	Vesiclepedia_260	10888925	Homo sapiens	Transfer of the chemokine receptor CCR5 between cells by membrane-derived microparticles: a mechanism for cellular human immunodeficiency virus 1 infection	Mononuclear cells	Protein	Differential centrifugation Filtration	Microparticles
112	Vesiclepedia_323	20304794	Homo sapiens	Functional delivery of viral miRNAs via exosomes	B cells	Protein	Differential centrifugation	Exosomes
113	Vesiclepedia_813	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Differential centrifugation Filtration ExoQuick Ultracentrifugation	Exosomes
114	Vesiclepedia_535	23818640	Homo sapiens	Modulation of B-cell exosome proteins by gamma herpesvirus infection.	B cells	Protein	-	Exosomes/Microvesicles/Oncosomes/Microparticles
115	Vesiclepedia_277	22030351	Homo sapiens	Expression of PTRF in PC-3 cells modulates cholesterol dynamics and the actin cytoskeleton impacting secretion pathways	Prostate cancer cells	Protein	Differential centrifugation	Exosomes
116	Vesiclepedia_83	20949044	Homo sapiens	Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line	Lung cancer cells	Protein miRNA	Differential centrifugation Filtration Ultracentrifugation	Exosomes
117	Vesiclepedia_1050	28842968	Homo sapiens	Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles.	Colorectal cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
118	Vesiclepedia_1250	24939845	Homo sapiens	Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein.	Leukemia cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
119	Vesiclepedia_980	25471885	Drosophila melanogaster	The ESCRT machinery regulates the secretion and long-range activity of Hedgehog.	Drosophila wing imaginal Disc	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
120	Vesiclepedia_566	26858453	Homo sapiens	Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes	Dendritic cells	Protein	Differential centrifugation Ultracentrifugation Immunobeads (Igg1 PD)	Extracellular vesicles
121	Vesiclepedia_1053	29115712	Mus musculus	Proteomic Profiling of Exosomes Secreted by Breast Cancer Cells with Varying Metastatic Potential.	Breast cancer cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
122	Vesiclepedia_454	22669077	Homo sapiens	The proteome of erythrocyte-derived microparticles from plasma: new clues for erythrocyte aging and vesiculation.	Plasma	Protein	-	Microparticles
123	Vesiclepedia_913	28687758	Sus scrofa	Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers	Polarised retinal pigmented epithelial cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
124	Vesiclepedia_544	23977379	Listeria monocytogenes	Transcription Factor σ(B) Plays an Important Role in the Production of Extracellular Membrane-Derived Vesicles in Listeria monocytogenes.	Listeria monocytogenes	Protein	-	Membrane vesicles
125	Vesiclepedia_569	26858453	Homo sapiens	Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes	Dendritic cells	Protein	Differential centrifugation Ultracentrifugation Immunobeads (CD9 FT)	Extracellular vesicles
126	Vesiclepedia_710	28811610	Homo sapiens	Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA.	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
127	Vesiclepedia_370	16456881	Neisseria meningitidis	Outer membrane vesicles from group B Neisseria meningitidis delta gna33 mutant: proteomic and immunological comparison with detergent-derived outer membrane vesicles.	Neisseria meningitidis	Protein	-	Membrane vesicles
128	Vesiclepedia_748	29988836	Homo sapiens	Ultrafiltration and size exclusion chromatography combined with asymmetrical-flow field-flow fractionation for the isolation and characterisation of extracellular vesicles from urine	Urine	Protein	Filtration Size exclusion chromatography	Extracellular vesicles
129	Vesiclepedia_1274	23807490	Homo sapiens	Glioma microvesicles carry selectively packaged coding and non-coding RNAs which alter gene expression in recipient cells.	Glioblastoma cells	Protein miRNA	Differential centrifugation	Microvesicles
130	Vesiclepedia_472	23043909	Pseudomonas syringae	Virulence factors are released in association with outer membrane vesicles of Pseudomonas syringae pv. tomato T1 during normal growth.	Pseudomonas syringae	Protein	-	Membrane vesicles
131	Vesiclepedia_932	29207636	Homo sapiens	Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer.	Bladder cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
132	Vesiclepedia_82	20949044	Homo sapiens	Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line	Stomach cancer cells	Protein miRNA	Differential centrifugation Filtration Ultracentrifugation	Exosomes
133	Vesiclepedia_61	17133577	Mus musculus	Association of citrullinated proteins with synovial exosomes.	Synovial fluid	Protein	Differential centrifugation Sucrose density gradient	Exosomes
134	Vesiclepedia_41	15908444	Homo sapiens	Exosomal-like vesicles are present in human blood plasma.	Mast cells	Protein	Differential centrifugation Filtration Sucrose density gradient	Exosomes
135	Vesiclepedia_1263	24371517	Homo sapiens	Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients.	Urine	Protein	Differential centrifugation Ultracentrifugation	Exosomes
136	Vesiclepedia_301	19234131	Homo sapiens	Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR	Endothelial cells	Protein	Differential centrifugation	Microvesicles
137	Vesiclepedia_743	29988836	Homo sapiens	Ultrafiltration and size exclusion chromatography combined with asymmetrical-flow field-flow fractionation for the isolation and characterisation of extracellular vesicles from urine	Urine	Protein	Filtration Size exclusion chromatography	Extracellular vesicles
138	Vesiclepedia_897	26100252	Homo sapiens	Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts	Chronic lymphocytic leukemia cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
139	Vesiclepedia_741	25157233	Homo sapiens	Extravillous trophoblast cells-derived exosomes promote vascular smooth muscle cell migration.	Placenta	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
140	Vesiclepedia_1012	22711894	Homo sapiens	Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages.	Macrophages	Protein	Differential centrifugation Filtration Ultracentrifugation	Microvesicles/Exosomes
141	Vesiclepedia_1016	22711894	Homo sapiens	Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages.	Macrophages	Protein Lipids	Differential centrifugation Filtration Ultracentrifugation	Exosomes
142	Vesiclepedia_392	19351151	Mus musculus	Characterization of vesicles secreted from insulinoma NIT-1 cells.	Pancreatic cells	Protein	-	Exosomes
143	Vesiclepedia_1023	22327366	Homo sapiens	Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs.	Vascular endothelial cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
144	Vesiclepedia_108	21601258	Homo sapiens	Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage.	Ascites	Protein miRNA	Differential centrifugation Sucrose density gradient Immunobeads (EpCAM, CD24)	Exosomes
145	Vesiclepedia_747	29988836	Homo sapiens	Ultrafiltration and size exclusion chromatography combined with asymmetrical-flow field-flow fractionation for the isolation and characterisation of extracellular vesicles from urine	Urine	Protein	Filtration Size exclusion chromatography	Extracellular vesicles
146	Vesiclepedia_619	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Melanoma cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
147	Vesiclepedia_79	20458337	Homo sapiens	MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 1	B cells	Protein	Differential centrifugation Sucrose density gradient Immunobeads (MHC Class II)	Exosomes
148	Vesiclepedia_719	26148937	Homo sapiens	Proteomics profiling of cholangiocarcinoma exosomes: A potential role of oncogenic protein transferring in cancer progression.	Cholangiocarcinoma cells	Protein	Differential centrifugation Ultracentrifugation Filtration	Exosomes
149	Vesiclepedia_439	22129587	Bos taurus	Bovine milk exosome proteome.	Bovine milk	Protein	-	Exosomes/Membrane vesicles
150	Vesiclepedia_763	29953723	Salmo salar	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Leukocytes	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
151	Vesiclepedia_923	25483805	Homo sapiens	Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties	Embryonic kidney cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
152	Vesiclepedia_519	23585444	Homo sapiens	Identification and characterization of proteins isolated from microvesicles derived from human lung cancer pleural effusions.	Malignant pleural effusions	Protein	-	Exosomes/Microvesicles/Ectosomes/Microparticles
153	Vesiclepedia_1244	25167841	Homo sapiens	Antibody-coupled monolithic silica microtips for highthroughput molecular profiling of circulating exosomes.	Serum	Protein	CD9 antibody to Mass Spectrometric Immunoassay monolith pipette tips	Exosomes
154	Vesiclepedia_768	29953723	Salmo salar	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Leukocytes	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
155	Vesiclepedia_1213	29127410	Homo sapiens	Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies.	Bronchial epithelial cells	Protein	Ultracentrifugation	Extracellular vesicles
156	Vesiclepedia_539	23853596	Trichomonas vaginalis	Trichomonas vaginalis Exosomes Deliver Cargo to Host Cells and Mediate Host∶Parasite Interactions.	Trichomonas vaginalis	Protein	-	Exosomes/Microvesicles
157	Vesiclepedia_693	28170197	Homo sapiens	Enhanced Cardioprotection by Human Endometrium Mesenchymal Stem Cells Driven by Exosomal MicroRNA-21	Bone marrow mesenchymal stem cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
158	Vesiclepedia_1063	30006486	Homo sapiens	The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells.	Astrocytoma cells	Protein	Filtration Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
159	Vesiclepedia_724	25471207	Homo sapiens	Intraluminal proteome and peptidome of human urinary extracellular vesicles.	Urine	Protein	Differential centrifugation Hydrostatic filtration dialysis Ultrafiltration	Exosomes
160	Vesiclepedia_453	22635005	Homo sapiens	Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET.	Melanoma cells	Protein	-	Exosomes
161	Vesiclepedia_935	29207636	Homo sapiens	Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer.	Urine	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
162	Vesiclepedia_798	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Embryonic kidney cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
163	Vesiclepedia_486	23230278	Homo sapiens	Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids.	Colorectal cancer cells	Protein	-	Exosomes/Extracellular vesicles/Microvesicles
164	Vesiclepedia_1271	24058411	Homo sapiens	Osteoprotegerin in exosome-like vesicles from human cultured tubular cells and urine.	Proximal tubular epithelial cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
165	Vesiclepedia_274	12021310	Homo sapiens	Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles	Melanoma cells	Protein	Differential centrifugation Ultracentrifugation	Microvesicles
166	Vesiclepedia_1259	24400796	Rattus norvegicus	Exosomal proteins in the aqueous humor as novel biomarkers in patients with neovascular age-related macular degeneration.	Retinal glial cells	Protein	ExoQuick	Exosomes
167	Vesiclepedia_1149	22807456	Homo sapiens	Quantitative proteomic analysis of exosomes from HIV-1-infected lymphocytic cells.	Lymphocytes	Protein	Differential centrifugation Ultracentrifugation	Exosomes
168	Vesiclepedia_31	10572093	Homo sapiens	Activated platelets release two types of membrane vesicles: microvesicles by surface shedding and exosomes derived from exocytosis of multivesicular bodies and alpha-granules.	Platelets	Protein	Differential centrifugation Sucrose density gradient	Exosomes
169	Vesiclepedia_802	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
170	Vesiclepedia_740	25157233	Homo sapiens	Extravillous trophoblast cells-derived exosomes promote vascular smooth muscle cell migration.	Placenta choriocarcinoma cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
171	Vesiclepedia_746	29988836	Homo sapiens	Ultrafiltration and size exclusion chromatography combined with asymmetrical-flow field-flow fractionation for the isolation and characterisation of extracellular vesicles from urine	Urine	Protein	Filtration Size exclusion chromatography	Extracellular vesicles
172	Vesiclepedia_78	20224111	Homo sapiens	Proteomics analysis of bladder cancer exosomes.	Urine	Protein	Differential centrifugation Sucrose density gradient	Exosomes
173	Vesiclepedia_288	12196479	Homo sapiens	Type 1 and type 2 diabetic patients display different patterns of cellular microparticles	Plasma	Protein Lipids	Differential centrifugation FACS	Microparticles
174	Vesiclepedia_231	2294986	Homo sapiens	Direct detection of activated platelets and platelet-derived microparticles in humans	Plasma	Protein	FACS	Microparticles
175	Vesiclepedia_22	15940614	Homo sapiens	Human colorectal cancer cells induce T-cell death through release of proapoptotic microvesicles: role in immune escape.	Colorectal cancer cells	Protein	Differential centrifugation	Exosomes
176	Vesiclepedia_215	21364924	Homo sapiens	Thermal- and oxidative stress causes enhanced release of NKG2D ligand-bearing immunosuppressive exosomes in leukemia/lymphoma T and B cells	B cells	Protein	Differential centrifugation Ultracentrifugation Filtration Sucrose density gradient FACS	Exosomes
177	Vesiclepedia_821	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Filtration Ultracentrifugation Sucrose and deuterium oxide density cushion	Exosomes
178	Vesiclepedia_711	28811610	Homo sapiens	Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA.	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Microvesicles
179	Vesiclepedia_382	18373357	Homo sapiens	Isolation and identification of potential urinary microparticle biomarkers of bladder cancer.	Urine	Protein	-	Microparticles
180	Vesiclepedia_1194	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
181	Vesiclepedia_869	24614226	Ovis aries	Extracellular vesicles in luminal fluid of the ovine uterus	Uterine luminal fluid	Protein	Differential centrifugation Filtration ExoQuick	Extracellular vesicles
182	Vesiclepedia_1267	24218614	Homo sapiens	Unexpected gain of function for the scaffolding protein plectin due to mislocalization in pancreatic cancer.	Pancreatic adenocarcinoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
183	Vesiclepedia_588	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Colorectal cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
184	Vesiclepedia_236	10648405	Homo sapiens	Cellular origin and procoagulant properties of microparticles in meningococcal sepsis	Plasma	Protein	Differential centrifugation FACS	Microparticles
185	Vesiclepedia_466	22966805	Acinetobacter baumannii	Extracellular proteome of a highly invasive multidrug-resistant clinical strain of Acinetobacter baumannii.	Acinetobacter baumannii	Protein	-	Membrane vesicles
186	Vesiclepedia_1045	28725021	Bos taurus	Bovine milk-derived exosomes from colostrum are enriched with proteins implicated in immune response and growth.	Bovine milk	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
187	Vesiclepedia_485	23214914	Trypanosoma cruzi	Proteomic analysis of Trypanosoma cruzi secretome: characterization of two populations of extracellular vesicles and soluble proteins.	Metacyclic trypomastigotes	Protein	-	Exosomes/Extracellular vesicles/Ectosomes
188	Vesiclepedia_278	10233897	Homo sapiens	Elevated levels of circulating procoagulant microparticles in patients with paroxysmal nocturnal hemoglobinuria and aplastic anemia	Platelets	Protein Lipids	Differential centrifugation FACS	Microparticles
189	Vesiclepedia_226	12514112	Homo sapiens	Intravascular tissue factor initiates coagulation via circulating microvesicles and platelets	Platelets	Protein	Differential centrifugation	Microvesicles
190	Vesiclepedia_406	19806257	Homo sapiens	Proteomic and functional characterisation of platelet microparticle size classes.	Platelets	Protein	-	Microparticles
191	Vesiclepedia_786	29953723	Oncorhynchus tshawytscha	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Embryonic cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
192	Vesiclepedia_88	20949044	Homo sapiens	Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line	Stomach cancer cells	Protein miRNA	Differential centrifugation Filtration Ultracentrifugation	Exosomes
193	Vesiclepedia_1129	23954818	Homo sapiens	Qualitative changes in the proteome of extracellular vesicles accompanying cancer cell transition to mesenchymal state.	Squamous carcinoma cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
194	Vesiclepedia_1079	25104112	Homo sapiens	Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy.	Plasma	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Exosomes
195	Vesiclepedia_659	29982104	Mus musculus	NRP-1 targeted and cargo-loaded exosomes facilitate simultaneous imaging and therapy of glioma in vitro and in vivo.	Macrophages	Protein	Differential centrifugation Ultracentrifugation Ultrafiltration	Exosomes
196	Vesiclepedia_1069	29937354	Homo sapiens	Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors.	Glioblastoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
197	Vesiclepedia_1163	29904572	Bos taurus	A subset of extracellular vesicles carries the bulk of microRNAs in commercial dairy cow's milk.	Bovine milk	Protein miRNA	Differential centrifugation Density gradient centrifugation	Extracellular vesicles
198	Vesiclepedia_80	20458337	Homo sapiens	MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis -Sample 2	B cells	Protein	Differential centrifugation Sucrose density gradient Immunobeads (MHC Class II)	Exosomes
199	Vesiclepedia_1278	22437826	Drosophila melanogaster	Mechanism of evenness interrupted (Evi)-exosome release at synaptic boutons.	Drosophila S2 cells	Protein	Ultracentrifugation Density gradient centrifugation	Exosomes
200	Vesiclepedia_562	26858453	Homo sapiens	Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes	Dendritic cells	Protein	Differential centrifugation Ultracentrifugation OptiPrep density gradient	Microvesicles
201	Vesiclepedia_1272	24058411	Homo sapiens	Osteoprotegerin in exosome-like vesicles from human cultured tubular cells and urine.	Urine	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
202	Vesiclepedia_279	16192427	Homo sapiens	Circulating endothelial microparticles are associated with vascular dysfunction in patients with end-stage renal failure	Plasma	Protein	Differential centrifugation FACS	Microparticles
203	Vesiclepedia_1219	27872147	Homo sapiens	Primary Human and Rat .-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity.	Islets	Protein	Differential centrifugation Ultracentrifugation	Exosomes
204	Vesiclepedia_71	19801663	Homo sapiens	Microenvironmental pH is a key factor for exosome traffic in tumor cells.	Melanoma cells	Protein Lipids	Differential centrifugation Sucrose density gradient	Exosomes
205	Vesiclepedia_7	12626558	Mus musculus	Mast cell-derived exosomes induce phenotypic and functional maturation of dendritic cells and elicit specific immune responses in vivo.	Mast cells	Protein	Differential centrifugation	Exosomes
206	Vesiclepedia_949	28819550	Mus musculus	Effects of storage temperature on airway exosome integrity for diagnostic and functional analyses.	Bronchoalveolar lavage fluid	Protein	Differential centrifugation Ultracentrifugation	Exosomes
207	Vesiclepedia_412	20156641	Homo sapiens	Proteomics of microparticles after deep venous thrombosis.	Plasma	Protein	-	Membrane vesicles/Microparticles
208	Vesiclepedia_1174	29881354	Rattus norvegicus	Effects of Acute Aerobic Exercise on Rats Serum Extracellular Vesicles Diameter, Concentration and Small RNAs Content.	Serum	Protein miRNA	ExoQuick	Extracellular vesicles
209	Vesiclepedia_429	21595033	Homo sapiens	Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.	Urine	Protein	-	Exosomes
210	Vesiclepedia_673	29953960	Homo sapiens	Exosomes derived from calcium oxalate-exposed macrophages enhance IL-8 production from renal cells, neutrophil migration and crystal invasion through extracellular matrix.	Macrophages	Protein	Microfiltration Differential centrifugation Ultracentrifugation	Exosomes
211	Vesiclepedia_984	25287304	Candida albicans	Compositional and immunobiological analyses of extracellular vesicles released by Candida albicans.	Candida albicans	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
212	Vesiclepedia_1062	30006486	Homo sapiens	The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells.	Astrocytoma cells	Protein	Filtration Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
213	Vesiclepedia_674	29953960	Homo sapiens	Exosomes derived from calcium oxalate-exposed macrophages enhance IL-8 production from renal cells, neutrophil migration and crystal invasion through extracellular matrix.	Macrophages	Protein	Microfiltration Differential centrifugation Ultracentrifugation	Exosomes
214	Vesiclepedia_131	19188015	Homo sapiens	Systemic presence and tumor-growth promoting effect of ovarian carcinoma released exosomes	Ascites	Protein Lipids	Differential centrifugation Sucrose density gradient	Exosomes
215	Vesiclepedia_617	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Melanoma cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
216	Vesiclepedia_27	19109410	Homo sapiens	Proteomic and immunologic analyses of brain tumor exosomes.	Medulloblastoma cells	Protein	Differential centrifugation Sucrose density gradient	Exosomes
217	Vesiclepedia_526	23660474	Homo sapiens	Heterogeneity in neutrophil microparticles reveals distinct proteome and functional properties.	Neutrophils	Protein	-	Microparticles
218	Vesiclepedia_1125	24347249	Homo sapiens	Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation ExoQuick	Exosomes
219	Vesiclepedia_1195	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
220	Vesiclepedia_791	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Embryonic kidney cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
221	Vesiclepedia_1234	25421927	Mus musculus	Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity.	Serum	miRNA Protein	Filtration Ultracentrifugation	Exosomes
222	Vesiclepedia_534	23818640	Homo sapiens	Modulation of B-cell exosome proteins by gamma herpesvirus infection.	B cells	Protein	-	Exosomes/Microvesicles/Oncosomes/Microparticles
223	Vesiclepedia_248	15741221	Homo sapiens	Tissue-factor-bearing microvesicles arise from lipid rafts and fuse with activated platelets to initiate coagulation	Monocytic leukemia cells	Protein	Differential centrifugation	Microvesicles
224	Vesiclepedia_198	21555566	Homo sapiens	Multiple recognition assay reveals prostasomes as promising plasma biomarkers for prostate cancer	Plasma	Protein	Differential centrifugation Ultracentrifugation Gel chromatography	Microvesicles
225	Vesiclepedia_56	12147373	Homo sapiens	Malignant effusions and immunogenic tumour-derived exosomes.	Ascites	Protein	Differential centrifugation Sucrose density gradient	Exosomes
226	Vesiclepedia_62	17133577	Mus musculus	Association of citrullinated proteins with synovial exosomes.	Synovial fluid	Protein	Differential centrifugation Sucrose density gradient	Exosomes
227	Vesiclepedia_169	21859146	Homo sapiens	Identification of a conserved glycan signature for microvesicles	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Microvesicles
228	Vesiclepedia_174	21842121	Mus musculus	Oligodendroglioma cells shed microvesicles which contain TRAIL as well as molecular chaperones and induce cell death in astrocytes	Oligodendrocytes	Protein	Differential centrifugation	Microvesicles
229	Vesiclepedia_992	24434149	Homo sapiens	In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome.	Ovarian cancer cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
230	Vesiclepedia_660	29964051	Homo sapiens	Cell-free therapy based on adipose tissue stem cell-derived exosomes promotes wound healing via the PI3K/Akt signaling pathway	Adipose tissue-derived stem cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
231	Vesiclepedia_577	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Breast cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
232	Vesiclepedia_491	23264574	Francisella novicida	Production of Outer Membrane Vesicles and Outer Membrane Tubes by Francisella novicida.	Francisella novicida	Protein	-	Membrane vesicles
233	Vesiclepedia_179	20686450	Homo sapiens	Comparison of three methods for isolation of urinary microvesicles to identify biomarkers of nephrotic syndrome	Urine	Protein	Differential centrifugation Ultracentrifugation	Microvesicles
234	Vesiclepedia_745	29988836	Homo sapiens	Ultrafiltration and size exclusion chromatography combined with asymmetrical-flow field-flow fractionation for the isolation and characterisation of extracellular vesicles from urine	Urine	Protein	Filtration Size exclusion chromatography	Extracellular vesicles
235	Vesiclepedia_430	21595033	Homo sapiens	Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.	Urine	Protein	-	Exosomes
236	Vesiclepedia_968	25844599	Homo sapiens	Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.	Serum	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
237	Vesiclepedia_568	26858453	Homo sapiens	Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes	Dendritic cells	Protein	Differential centrifugation Ultracentrifugation Immunobeads (CD9 PD)	Extracellular vesicles
238	Vesiclepedia_1004	23463506	Homo sapiens	The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes.	T cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
239	Vesiclepedia_60	17700640	Mus musculus	CD24 is a marker of exosomes secreted into urine and amniotic fluid.	Urine	Protein	Differential centrifugation Sucrose density gradient	Exosomes
240	Vesiclepedia_701	28811610	Homo sapiens	Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA.	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Microvesicles
241	Vesiclepedia_1245	25167841	Homo sapiens	Antibody-coupled monolithic silica microtips for highthroughput molecular profiling of circulating exosomes.	Serum	Protein	CD9 antibody to Mass Spectrometric Immunoassay monolith pipette tips	Exosomes
242	Vesiclepedia_481	23161513	Homo sapiens	Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.	Colorectal cancer cells	Protein	-	Exosomes
243	Vesiclepedia_17	11907077	Homo sapiens	TCR activation of human T cells induces the production of exosomes bearing the TCR/CD3/zeta complex.	T cells	Protein	Filtration Ultracentrifugation	Exosomes
244	Vesiclepedia_438	22114730	Staphylococcus aureus	Staphylococcus aureus produces membrane-derived vesicles that induce host cell death.	Staphylococcus aureus	Protein	-	Membrane vesicles/Nanovesicles
245	Vesiclepedia_707	28811610	Homo sapiens	Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA.	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
246	Vesiclepedia_851	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
247	Vesiclepedia_1314	-	Saccharomyces cerevisiae	Extracellular vesicles secreted by Saccharomyces cerevisiae are involved in cell wall remodelling	Saccharomyces cerevisiae	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
248	Vesiclepedia_1226	26154623	Homo sapiens	Size-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals	Plasma	Protein	Size exclusion chromatography	Extracellular vesicles
249	Vesiclepedia_54	14975938	Homo sapiens	Proteomic analysis of exosomes isolated from human malignant pleural effusions.	Malignant pleural effusions	Protein	Differential centrifugation Sucrose density gradient	Exosomes
250	Vesiclepedia_796	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Embryonic kidney cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
251	Vesiclepedia_919	28687758	Sus scrofa	Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers	Polarised retinal pigmented epithelial cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
252	Vesiclepedia_1144	23454749	Homo sapiens	BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression.	Bone marrow mesenchymal stromal cells	Protein	Differential centrifugation Ultracentrifugation Filtration ExoQuick	Exosomes
253	Vesiclepedia_829	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Filtration Ultracentrifugation Sucrose density gradient	Exosomes
254	Vesiclepedia_774	29953723	Salmo salar	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Leukocytes	Protein	Differential centrifugation	Apoptotic bodies
255	Vesiclepedia_1156	21212511	Homo sapiens	Proteomic analysis of two types of exosomes in human whole saliva.	Saliva	Protein	Differential centrifugation Filtration Ultracentrifugation Gel filtration	Exosomes
256	Vesiclepedia_178	20686450	Homo sapiens	Comparison of three methods for isolation of urinary microvesicles to identify biomarkers of nephrotic syndrome	Urine	Protein	Differential centrifugation Ultrafiltration	Microvesicles
257	Vesiclepedia_483	23214914	Trypanosoma cruzi	Proteomic analysis of Trypanosoma cruzi secretome: characterization of two populations of extracellular vesicles and soluble proteins.	Epimastigotes	Protein	-	Exosomes/Extracellular vesicles/Ectosomes
258	Vesiclepedia_928	25483805	Gallus gallus	Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties	Notochord cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
259	Vesiclepedia_778	29953723	Salmo salar	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Leukocytes	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
260	Vesiclepedia_995	24434149	Homo sapiens	In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome.	Ovarian cancer cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
261	Vesiclepedia_893	24946052	Homo sapiens	Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment	Lung cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
262	Vesiclepedia_1304	-	Saccharomyces cerevisiae	Extracellular vesicles secreted by Saccharomyces cerevisiae are involved in cell wall remodelling	Saccharomyces cerevisiae	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
263	Vesiclepedia_726	25471207	Homo sapiens	Intraluminal proteome and peptidome of human urinary extracellular vesicles.	Urine	Protein	Differential centrifugation Hydrostatic filtration dialysis Ultrafiltration	Exosomes
264	Vesiclepedia_384	18482993	Homo sapiens	Protein composition of human epididymosomes collected during surgical vasectomy reversal: a proteomic and genomic approach.	Epididymal fluid	Protein	-	Prostasomes
265	Vesiclepedia_809	29932869	Mus musculus	Exosomes derived from high-glucose-stimulated Schwann cells promote development of diabetic peripheral neuropathy	Schwann cells	protein	Filtration Differential centrifugation Ultracentrifugation	Exosomes
266	Vesiclepedia_1288	20399774	Mus musculus	C2C12 myoblasts release micro-vesicles containing mtDNA and proteins involved in signal transduction.	Mouse myoblast	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Microvesicles
267	Vesiclepedia_123	21235781	Homo sapiens	Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages.	Plasma	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
268	Vesiclepedia_161	21901833	Drosophila melanogaster	Proteomics analyses of microvesicles released by Drosophila Kc167 and S2 cells	Hematocytes	Protein PTM Ubiquitination	Differential centrifugation Sucrose density gradient Ultracentrifugation	Microvesicles
269	Vesiclepedia_1282	22345510	Rattus norvegicus	Characterization of membrane-shed microvesicles from cytokine-stimulated .-cells using proteomics strategies.	Insulinoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
270	Vesiclepedia_69	19812188	Rattus norvegicus	Immature dendritic cell-derived exosomes rescue septic animals via milk fat globule epidermal growth factor VIII.	Dendritic cells	Protein	Differential centrifugation Sucrose density gradient	Exosomes
271	Vesiclepedia_1124	24347249	Homo sapiens	Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation ExoQuick	Exosomes
272	Vesiclepedia_465	22909304	Pseudomonas aeruginosa	Identification of proteins associated with the Pseudomonas aeruginosa biofilm extracellular matrix.	Pseudomonas aeruginosa	Protein	-	Membrane vesicles
273	Vesiclepedia_794	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Embryonic kidney cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
274	Vesiclepedia_109	21601258	Homo sapiens	Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage.	Malignant pleural effusions	Protein miRNA	Differential centrifugation Sucrose density gradient Immunobeads (EpCAM)	Exosomes
275	Vesiclepedia_1162	22641613	Homo sapiens	Application of systems biology principles to protein biomarker discovery: urinary exosomal proteome in renal transplantation.	Urine	Protein	Differential centrifugation Ultracentrifugation	Exosomes
276	Vesiclepedia_795	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Embryonic kidney cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
277	Vesiclepedia_522	23645497	Canis lupus familiaris	Oncogenic H-Ras reprograms Madin-Darby canine kidney (MDCK) cell-derived exosomal proteins following epithelial-mesenchymal transition.	Kidney cells	Protein	-	Exosomes/Extracellular vesicles
278	Vesiclepedia_616	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Lung cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
279	Vesiclepedia_259	18425114	Homo sapiens	Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells	Glioma cells	Protein	Differential centrifugation Ultracentrifugation	Microvesicles
280	Vesiclepedia_860	25776846	Homo sapiens	Human thymic epithelial primary cells produce exosomes carrying tissue-restricted antigens	Epithelial cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
281	Vesiclepedia_1157	20662102	Mus musculus	Proteomic analysis identifies highly antigenic proteins in exosomes from M. tuberculosis-infected and culture filtrate protein-treated macrophages.	Macrophages	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
282	Vesiclepedia_699	28811610	Homo sapiens	Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA.	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
283	Vesiclepedia_890	24946052	Homo sapiens	Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment	Lung cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
284	Vesiclepedia_630	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Ovarian cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
285	Vesiclepedia_1027	24211404	Homo sapiens	Diabetic nephropathy induces changes in the proteome of human urinary exosomes as revealed by label-free comparative analysis.	Urine	Protein	Ultracentrifugation ExoQuick	Exosomes
286	Vesiclepedia_39	15210972	Mus musculus	Cells release prions in association with exosomes.	Mov neuroglial cell	Protein	Differential centrifugation Sucrose density gradient	Exosomes
287	Vesiclepedia_1247	25167841	Homo sapiens	Antibody-coupled monolithic silica microtips for highthroughput molecular profiling of circulating exosomes.	Serum	Protein	CD9 antibody to Mass Spectrometric Immunoassay monolith pipette tips	Exosomes
288	Vesiclepedia_1128	23954818	Homo sapiens	Qualitative changes in the proteome of extracellular vesicles accompanying cancer cell transition to mesenchymal state.	Squamous carcinoma cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
289	Vesiclepedia_867	24614226	Ovis aries	Extracellular vesicles in luminal fluid of the ovine uterus	Uterine luminal fluid	Protein	Differential centrifugation Filtration ExoQuick	Extracellular vesicles
290	Vesiclepedia_541	23935504	Homo sapiens	A Novel Role for Pro-Coagulant Microvesicles in the Early Host Defense against Streptococcus pyogenes.	Peripheral blood mononucelar cells	Protein	-	Microvesicles
291	Vesiclepedia_1112	24391718	Homo sapiens	Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
292	Vesiclepedia_224	10393703	Homo sapiens	In vitro generation of endothelial microparticles and possible prothrombotic activity in patients with lupus anticoagulant	Plasma	Protein	Differential centrifugation	Microparticles
293	Vesiclepedia_100	21828046	Rattus norvegicus	The proteo-lipidic composition of exosomes changes during reticulocyte maturation.	Reticulocytes	Protein Lipids	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
294	Vesiclepedia_256	9126269	Homo sapiens	Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations	Burkitt's lymphoma	Protein	Differential centrifugation Sucrose density gradient	Microvesicles
295	Vesiclepedia_1143	23454749	Homo sapiens	BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression.	Bone marrow mesenchymal stromal cells	Protein	Differential centrifugation Ultracentrifugation Filtration ExoQuick	Exosomes
296	Vesiclepedia_393	19369228	Homo sapiens	Proteomic analysis reveals presence of platelet microparticles in endothelial progenitor cell cultures.	Endothelial cells	Protein	-	Microparticles
297	Vesiclepedia_135	2777884	Cavia porcellus	Asymmetric Distribution of Phospholipids in the Membrane of Vesicles Released During In Vitro Maturation of Guinea Pig Reticulocytes: Evidence Precluding a Role for Aminophospholipid Translocase	Reticulocytes	Proteins Lipids	Differential centrifugation Ultracentrifugation	Exosomes
298	Vesiclepedia_999	24355714	Homo sapiens	Proteomic analysis and immune properties of exosomes released by macrophages infected with Mycobacterium avium.	Leukemia cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
299	Vesiclepedia_43	17076679	Homo sapiens	Specific isolation of placenta-derived exosomes from the circulation of pregnant women and their immunoregulatory consequences.	Plasma	Protein	Size exclusion chromatography Ultracentrifugation Immunobeads (CD3, CD19, CD56, CD83, PLAP)	Exosomes
300	Vesiclepedia_752	29963269	Homo sapiens	Mining of potential microRNAs with clinical correlation - regulation of syndecan-1 expression by miR-122-5p altered mobility of breast cancer cells and possible correlation with liver injury	Hepatoma cells	Protein	Total Exosome Isolation Kit Differential centrifugation	Exosomes
301	Vesiclepedia_839	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
302	Vesiclepedia_732	25359493	Homo sapiens	Proteomic signatures of extracellular vesicles secreted by nonmineralizing and mineralizing human osteoblasts and stimulation of tumor cell growth.	Osteoblasts	Protein	Differential centrifugation Ultracentrifugation	Matrix vesicles
303	Vesiclepedia_955	27601599	Homo sapiens	Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components.	Breast milk	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
304	Vesiclepedia_947	28819550	Mus musculus	Effects of storage temperature on airway exosome integrity for diagnostic and functional analyses.	Bronchoalveolar lavage fluid	Protein	Differential centrifugation Ultracentrifugation	Exosomes
305	Vesiclepedia_974	22808001	Homo sapiens	Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment.	Serum	Protein	Filtration ExoQuick	Exosomes
306	Vesiclepedia_866	24614226	Ovis aries	Extracellular vesicles in luminal fluid of the ovine uterus	Uterine luminal fluid	Protein	Differential centrifugation Filtration ExoQuick	Extracellular vesicles
307	Vesiclepedia_467	23000592	Homo sapiens	In-depth analysis of the secretome identifies three major independent secretory pathways in differentiating human myoblasts.	Neonatal myoblast cells	Protein	-	Microvesicles/Nanovesicles
308	Vesiclepedia_855	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
309	Vesiclepedia_91	21252909	Homo sapiens	Diacylglycerol kinase a regulates the formation and polarisation of mature multivesicular bodies involved in the secretion of Fas ligand-containing exosomes in T lymphocytes	T cells	Protein Lipids	Differential centrifugation Ultracentrifugation	Exosomes
310	Vesiclepedia_36	19367702	Mus musculus	Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.	Hepatocytes	Protein	Differential centrifugation Filtration	Exosomes
311	Vesiclepedia_415	20687614	Myxococcus xanthus	Profiling the outer membrane proteome during growth and development of the social bacterium Myxococcus xanthus by selective biotinylation and analyses of outer membrane vesicles.	Myxococcus xanthus	Protein	-	Membrane vesicles
312	Vesiclepedia_578	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Breast cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
313	Vesiclepedia_921	28687758	Sus scrofa	Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers	Polarised retinal pigmented epithelial cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
314	Vesiclepedia_502	23436686	Homo sapiens	A comprehensive characterization of membrane vesicles released by autophagic human endothelial cells.	Endothelial cells	Protein	-	Membrane vesicles/Extracellular vesicles
315	Vesiclepedia_1258	24400796	Homo sapiens	Exosomal proteins in the aqueous humor as novel biomarkers in patients with neovascular age-related macular degeneration.	Aqueous humor	Protein	ExoQuick	Exosomes
316	Vesiclepedia_1038	29887978	Homo sapiens	Evaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing.	Serum	Protein miRNA	miRCURY Exosome Isolation Kit	Extracellular vesicles
317	Vesiclepedia_369	16212402	Homo sapiens	The platelet microparticle proteome.	Platelets	Protein	-	Microparticles
318	Vesiclepedia_952	27601599	Homo sapiens	Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components.	Breast milk	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
319	Vesiclepedia_1067	29937354	Homo sapiens	Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors.	Glioblastoma cells	Protein	Differential centrifugation Filtration	Microvesicles
320	Vesiclepedia_1132	23861904	Homo sapiens	Exosomal signaling during hypoxia mediates microvascular endothelial cell migration and vasculogenesis.	Placental mesenchymal stem cells	Protein	Differential centrifugation Ultracentrifugation Ultrafiltration Density gradient centrifugation	Exosomes
321	Vesiclepedia_512	23533145	Homo sapiens	In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.	Urine	Protein	-	Exosomes/Microvesicles
322	Vesiclepedia_1256	24400796	Homo sapiens	Exosomal proteins in the aqueous humor as novel biomarkers in patients with neovascular age-related macular degeneration.	Retinal pigment epithelial cells	Protein	ExoQuick	Exosomes
323	Vesiclepedia_991	25138791	Homo sapiens	The exocyst and regulatory GTPases in urinary exosomes.	Urine	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
324	Vesiclepedia_353	24115447	Homo sapiens	Comparative proteomics evaluation of plasma exosome isolation techniques and assessment of the stability of exosomes in normal human blood plasma	Plasma	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
325	Vesiclepedia_193	21575145	Homo sapiens	Microvesicle-mediated release of soluble LH/hCG receptor (LHCGR) from transfected cells and placenta explants	Placenta	Protein	Differential centrifugation Ultracentrifugation	Microvesicles
326	Vesiclepedia_1092	25065644	Homo sapiens	Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells.	Duodenal cancer cells	Protein	Differential centrifugation Filtration Ultrafiltration	Exosomes
327	Vesiclepedia_1071	29937354	Homo sapiens	Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors.	Glioblastoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
328	Vesiclepedia_1155	21212511	Homo sapiens	Proteomic analysis of two types of exosomes in human whole saliva.	Saliva	Protein	Differential centrifugation Filtration Ultracentrifugation Gel filtration	Exosomes
329	Vesiclepedia_792	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Embryonic kidney cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
330	Vesiclepedia_249	15741221	Homo sapiens	Tissue-factor-bearing microvesicles arise from lipid rafts and fuse with activated platelets to initiate coagulation	Monocytes	Protein	Differential centrifugation	Microvesicles
331	Vesiclepedia_1154	22057275	Homo sapiens	Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease.	Cerebrospinal fluid	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
332	Vesiclepedia_291	15072974	Rattus norvegicus	Endothelium-derived microparticles impair endothelial function in vitro	Endothelial cells	Protein	Differential centrifugation Ultracentrifugation FACS	Microparticles
333	Vesiclepedia_960	26047123	Bos taurus	Oral administration of bovine milk derived extracellular vesicles attenuates arthritis in two mouse models.	Bovine milk	Protein	Differential centrifugation Ultracentrifugation Filtration	Extracellular vesicles
334	Vesiclepedia_601	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Kidney cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
335	Vesiclepedia_1140	23454749	Homo sapiens	BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression.	Bone marrow mesenchymal stromal cells	Protein	Differential centrifugation Ultracentrifugation Filtration ExoQuick	Exosomes
336	Vesiclepedia_1039	27770278	Homo sapiens	Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease.	Glioblastoma cells	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Extracellular vesicles
337	Vesiclepedia_1032	29887978	Homo sapiens	Evaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing.	Serum	Protein miRNA	exoEasy columns	Extracellular vesicles
338	Vesiclepedia_10	11390481	Mus musculus	Proteomic analysis of dendritic cell-derived exosomes: a secreted subcellular compartment distinct from apoptotic vesicles.	Dendritic cells	Protein	Differential centrifugation Sucrose density gradient	Exosomes
339	Vesiclepedia_1158	20662102	Mus musculus	Proteomic analysis identifies highly antigenic proteins in exosomes from M. tuberculosis-infected and culture filtrate protein-treated macrophages.	Macrophages	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
340	Vesiclepedia_772	29953723	Salmo salar	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Leukocytes	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
341	Vesiclepedia_1309	-	Saccharomyces cerevisiae	Extracellular vesicles secreted by Saccharomyces cerevisiae are involved in cell wall remodelling	Saccharomyces cerevisiae	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
342	Vesiclepedia_1168	29907695	Mus musculus	Cancer cells copy migratory behavior and exchange signaling networks via extracellular vesicles.	Melanoma cells	Protein miRNA	Differential centrifugation Ultracentrifugation	Extracellular vesicles
343	Vesiclepedia_458	22740476	Homo sapiens	Restoration of full-length APC protein in SW480 colon cancer cells induces exosome-mediated secretion of DKK-4.	Colorectal cancer cells	Protein	-	Exosomes
344	Vesiclepedia_261	12805058	Homo sapiens	Sickle blood contains tissue factor-positive microparticles derived from endothelial cells and monocytes	Plasma	Protein Lipids	Differential centrifugation Ultracentrifugation FACS	Microparticles
345	Vesiclepedia_285	12796750	Homo sapiens	High levels of circulating endothelial microparticles in patients with acute coronary syndromes	Plasma	Protein	Differential centrifugation FACS	Microparticles
346	Vesiclepedia_967	25844599	Homo sapiens	Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.	Serum	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
347	Vesiclepedia_102	21082674	Homo sapiens	Comprehensive analysis of low-abundance proteins in human urinary exosomes using peptide ligand library technology, peptide OFFGEL fractionation and nanoHPLC-chip-MS/MS.	Urine	Protein	Differential centrifugation Ultracentrifugation	Exosomes
348	Vesiclepedia_661	29956871	Homo sapiens	Expression analysis of extracellular microRNA in bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis	Bronchoalveolar lavage fluid	Protein	Differential centrifugation Ultracentrifugation Filtration	Exosomes
349	Vesiclepedia_1030	26378940	Homo sapiens	Redefining the Breast Cancer Exosome Proteome by Tandem Mass Tag Quantitative Proteomics and Multivariate Cluster Analysis.	Breast cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
350	Vesiclepedia_1115	24391718	Homo sapiens	Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
351	Vesiclepedia_371	16456881	Neisseria meningitidis	Outer membrane vesicles from group B Neisseria meningitidis delta gna33 mutant: proteomic and immunological comparison with detergent-derived outer membrane vesicles.	Neisseria meningitidis	Protein	-	Membrane vesicles
352	Vesiclepedia_850	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
353	Vesiclepedia_111	21601258	Homo sapiens	Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage.	Serum	Protein miRNA	Differential centrifugation Sucrose density gradient Immunobeads (CD24)	Exosomes
354	Vesiclepedia_987	25261472	Homo sapiens	Complex N-linked glycans serve as a determinant for exosome/microvesicle cargo recruitment.	Melanoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes/Microvesicles
355	Vesiclepedia_1091	25065644	Homo sapiens	Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells.	Duodenal cancer cells	Protein	Differential centrifugation Filtration Ultrafiltration	Exosomes
356	Vesiclepedia_1238	25329303	Homo sapiens	Rapid isolation of extracellular vesicles from cell culture and biological fluids using a synthetic peptide with specific affinity for heat shock proteins.	Urine	Protein	Ultracentrifugation	Extracellular vesicles
357	Vesiclepedia_76	20224111	Homo sapiens	Proteomics analysis of bladder cancer exosomes.	Bladder cancer cells	Protein	Differential centrifugation Sucrose density gradient	Exosomes
358	Vesiclepedia_1068	29937354	Homo sapiens	Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors.	Glioblastoma cells	Protein	Differential centrifugation Filtration	Microvesicles
359	Vesiclepedia_873	24614226	Ovis aries	Extracellular vesicles in luminal fluid of the ovine uterus	Uterine luminal fluid	Protein	Differential centrifugation Filtration ExoQuick	Extracellular vesicles
360	Vesiclepedia_830	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Filtration Ultracentrifugation Sucrose density gradient	Exosomes
361	Vesiclepedia_273	12021310	Homo sapiens	Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles	T cells	Protein	Differential centrifugation Ultracentrifugation	Microvesicles
362	Vesiclepedia_934	29207636	Homo sapiens	Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer.	Bladder cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
363	Vesiclepedia_25	15111327	Homo sapiens	Proteomic analysis of exosomes secreted by human mesothelioma cells.	Mesothelioma cells	Protein	Differential centrifugation	Exosomes
364	Vesiclepedia_180	20686450	Homo sapiens	Comparison of three methods for isolation of urinary microvesicles to identify biomarkers of nephrotic syndrome	Urine	Protein	Differential centrifugation Ultracentrifugation Size exclusion chromatography Filtration	Microvesicles
365	Vesiclepedia_144	22723089	Homo sapiens	Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes.	Prostate cancer cells	Protein	Sucrose density gradient	Exosomes
366	Vesiclepedia_834	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Differential centrifugation Filtration ExoQuick Ultracentrifugation	Exosomes
367	Vesiclepedia_114	21557262	Homo sapiens	Proteomic identification of exosomal LRG1: A potential urinary biomarker for detecting NSCLC.	Urine	Protein	Differential centrifugation Ultracentrifugation	Exosomes
368	Vesiclepedia_189	21741384	Homo sapiens	A filtration-based protocol to isolate human plasma membrane-derived vesicles and exosomes from blood plasma	Plasma	Protein	Differential centrifugation Filtration	Exosomes
369	Vesiclepedia_346	22965126	Mus musculus	Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells.	Neuronal cells	Protein miRNA	Differential centrifugation Filtration Ultracentrifugation	Exosomes
370	Vesiclepedia_1095	24976626	Homo sapiens	Exosomal transfer from human renal proximal tubule cells to distal tubule and collecting duct cells.	Renal proximal tubule cells	Protein	Differential centrifugation Ultracentrifugation Immunoaffinity	Exosomes
371	Vesiclepedia_414	20559436	Saccharomyces cerevisiae	Characterization of yeast extracellular vesicles: evidence for the participation of different pathways of cellular traffic in vesicle biogenesis.	Saccharomyces cerevisiae	Protein	-	Extracellular vesicles
372	Vesiclepedia_524	23658846	Mus musculus	Immunomodulatory impact of leishmania-induced macrophage exosomes: a comparative proteomic and functional analysis.	Macrophages	Protein	-	Exosomes
373	Vesiclepedia_1085	25104112	Homo sapiens	Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy.	Plasma	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Exosomes
374	Vesiclepedia_99	21828046	Rattus norvegicus	The proteo-lipidic composition of exosomes changes during reticulocyte maturation.	Reticulocytes	Protein Lipids	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
375	Vesiclepedia_433	22014850	Rattus norvegicus	Proteomics of microparticles after experimental pulmonary embolism.	Plasma	Protein	-	Microparticles
376	Vesiclepedia_771	29953723	Salmo salar	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Leukocytes	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
377	Vesiclepedia_958	26196085	Homo sapiens	Identification of prostate cancer biomarkers in urinary exosomes.	Urine	Protein	Differential centrifugation Ultracentrifugation Filtration	Exosomes
378	Vesiclepedia_994	24434149	Homo sapiens	In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome.	Ovarian cancer cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
379	Vesiclepedia_333	20976003	Homo sapiens	Selective release of microRNA species from normal and malignant mammary epithelial cells	Breast cancer cells	Protein miRNA	Differential centrifugation Filtration	Exosomes
380	Vesiclepedia_464	22909304	Pseudomonas aeruginosa	Identification of proteins associated with the Pseudomonas aeruginosa biofilm extracellular matrix.	Pseudomonas aeruginosa	Protein	-	Membrane vesicles
381	Vesiclepedia_240	10233897	Homo sapiens	Elevated levels of circulating procoagulant microparticles in patients with paroxysmal nocturnal hemoglobinuria and aplastic anemia	Platelets	Protein Lipids	Differential centrifugation FACS	Microparticles
382	Vesiclepedia_655	28290293	Bos taurus	Comparative proteomic analysis of milk-derived exosomes in human and bovine colostrum and mature milk samples by iTRAQ-coupled LC-MS/MS.	Bovine milk	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Exosomes
383	Vesiclepedia_1218	27872147	Homo sapiens	Primary Human and Rat .-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity.	Islets	Protein	Differential centrifugation Ultracentrifugation	Exosomes
384	Vesiclepedia_167	21859146	Homo sapiens	Identification of a conserved glycan signature for microvesicles	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Microvesicles
385	Vesiclepedia_197	21616097	Homo sapiens	Release of podocalyxin into the extracellular space. Role of metalloproteinases	Testicular cancer cells	Protein	Differential centrifugation	Microvesicles
386	Vesiclepedia_290	12196479	Homo sapiens	Type 1 and type 2 diabetic patients display different patterns of cellular microparticles	Plasma	Protein Lipids	Differential centrifugation FACS	Microparticles
387	Vesiclepedia_272	8896411	Homo sapiens	High shear stress can initiate both platelet aggregation and shedding of procoagulant containing microparticles	Platelets	Protein Lipids	Differential centrifugation FACS	Microparticles
388	Vesiclepedia_1082	25104112	Homo sapiens	Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy.	Plasma	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Exosomes
389	Vesiclepedia_112	21601258	Homo sapiens	Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage.	Serum	Protein miRNA	Differential centrifugation Sucrose density gradient	Exosomes
390	Vesiclepedia_1148	23173708	Rattus norvegicus	Wnt3a induces exosome secretion from primary cultured rat microglia.	Primary microglial cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
391	Vesiclepedia_336	20976003	Homo sapiens	Selective release of microRNA species from normal and malignant mammary epithelial cells	Breast cancer cells	Protein miRNA	Differential centrifugation Filtration	Exosomes
392	Vesiclepedia_265	18425114	Homo sapiens	Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells	Endothelial cells	Protein	Differential centrifugation Ultracentrifugation	Microvesicles
393	Vesiclepedia_1017	22711894	Homo sapiens	Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages.	Macrophages	Protein Lipids	Differential centrifugation Filtration Ultracentrifugation	Exosomes
394	Vesiclepedia_289	12196479	Homo sapiens	Type 1 and type 2 diabetic patients display different patterns of cellular microparticles	Plasma	Protein Lipids	Differential centrifugation FACS	Microparticles
395	Vesiclepedia_418	21049385	Homo sapiens	The plasma microparticle proteome.	Plasma	Protein	-	Microparticles
396	Vesiclepedia_37	10878338	Homo sapiens	Direct immunosuppressive effects of EBV-encoded latent membrane protein 1.	B cells	Protein	Differential centrifugation	Exosomes
397	Vesiclepedia_518	23585443	Homo sapiens	Proteome profiling of exosomes derived from human primary and metastatic colorectal cells reveal differential expression of key metastatic factors and signal transduction components.	Colorectal cancer cells	Protein	-	Exosomes/Membrane vesicles
398	Vesiclepedia_575	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Breast cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
399	Vesiclepedia_1305	-	Saccharomyces cerevisiae	Extracellular vesicles secreted by Saccharomyces cerevisiae are involved in cell wall remodelling	Saccharomyces cerevisiae	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
400	Vesiclepedia_58	17700640	Homo sapiens	CD24 is a marker of exosomes secreted into urine and amniotic fluid.	Amniotic fluid	Protein	Differential centrifugation Sucrose density gradient	Exosomes
401	Vesiclepedia_11	12519789	Homo sapiens	Proteomic and biochemical analyses of human B cell-derived exosomes. Potential implications for their function and multivesicular body formation.	B cells	Protein Lipids	Differential centrifugation Sucrose density gradient	Exosomes
402	Vesiclepedia_864	22046311	Mus musculus	Exosomes from Plasmodium yoelii-infected reticulocytes protect mice from lethal infections	Plasma	Protein	Differential centrifugation Filtration Sucrose density gradient Ultracentrifugation	Exosomes
403	Vesiclepedia_42	15908444	Homo sapiens	Exosomal-like vesicles are present in human blood plasma.	Bone marrow cells	Protein	Differential centrifugation Filtration Sucrose density gradient	Exosomes
404	Vesiclepedia_585	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Brain cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
405	Vesiclepedia_1047	28725021	Bos taurus	Bovine milk-derived exosomes from colostrum are enriched with proteins implicated in immune response and growth.	Bovine milk	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
406	Vesiclepedia_1302	-	Saccharomyces cerevisiae	Extracellular vesicles secreted by Saccharomyces cerevisiae are involved in cell wall remodelling	Saccharomyces cerevisiae	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
407	Vesiclepedia_118	21362503	Homo sapiens	Protein profile of exosomes from trabecular meshwork cells.	Tabecular meshwork cells	Protein	Differential centrifugation Sucrose density gradient	Exosomes
408	Vesiclepedia_181	20668554	Homo sapiens	Microvesicles derived from adult human bone marrow and tissue specific mesenchymal stem cells shuttle selected pattern of miRNAs	Mesenchymal stem cells	Protein miRNA	Differential centrifugation Ultracentrifugation	Microvesicles
409	Vesiclepedia_421	21136987	Helicobacter pylori	Proteomic and functional characterization of the outer membrane vesicles from the gastric pathogen Helicobacter pylori.	Helicobacter pylori	Protein	-	Membrane vesicles
410	Vesiclepedia_117	21505438	Homo sapiens	Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells.	Dendritic cells	Protein miRNA	Differential centrifugation Filtration Ultracentrifugation	Exosomes
411	Vesiclepedia_411	20124223	Homo sapiens	Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.	Squamous carcinoma cells	Protein	-	Exosomes
412	Vesiclepedia_884	29955024	Homo sapiens	Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells	Myeloid leukemia cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
413	Vesiclepedia_1240	25329303	Homo sapiens	Rapid isolation of extracellular vesicles from cell culture and biological fluids using a synthetic peptide with specific affinity for heat shock proteins.	Urine	Protein	Ultracentrifugation	Extracellular vesicles
414	Vesiclepedia_1307	-	Saccharomyces cerevisiae	Extracellular vesicles secreted by Saccharomyces cerevisiae are involved in cell wall remodelling	Saccharomyces cerevisiae	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
415	Vesiclepedia_431	21595033	Homo sapiens	Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.	Urine	Protein	-	Exosomes
416	Vesiclepedia_538	23844026	Homo sapiens	Characterization of human thymic exosomes.	Thymus	Protein	-	Exosomes
417	Vesiclepedia_804	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
418	Vesiclepedia_107	21763319	Homo sapiens	Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells.	Pancreatic adenocarcinoma cells	Protein	Differential centrifugation Filtration Ultrafiltration Ultracentrifugation	Exosomes
419	Vesiclepedia_318	19483673	Homo sapiens	Y-box protein-1 is actively secreted through a non-classical pathway and acts as an extracellular mitogen	Monocytes	Protein	Differential centrifugation Filtration	Microvesicles
420	Vesiclepedia_825	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Filtration Ultracentrifugation Sucrose density gradient	Exosomes
421	Vesiclepedia_68	19619303	Homo sapiens	Claudin-containing exosomes in the peripheral circulation of women with ovarian cancer.	Plasma	Protein	Differential centrifugation	Exosomes
422	Vesiclepedia_210	21368175	Homo sapiens	Cancer cell-derived microvesicles induce transformation by transferring tissue transglutaminase and fibronectin to recipient cells	Breast cancer cells	Protein	Differential centrifugation Filtration	Microvesicles
423	Vesiclepedia_571	26858453	Homo sapiens	Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes	Dendritic cells	Protein	Differential centrifugation Ultracentrifugation Immunobeads (CD63 FT)	Extracellular vesicles
424	Vesiclepedia_632	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Ovarian cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
425	Vesiclepedia_199	21609964	Homo sapiens	Characterization of extracellular circulating microRNA	Plasma	Protein	Differential centrifugation Filtration	Exosomes
426	Vesiclepedia_886	25102470	Homo sapiens	Examination of the specificity of tumor cell derived exosomes with tumor cells in vitro	Breast cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
427	Vesiclepedia_283	19234131	Homo sapiens	Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR	Colorectal cancer cells	Protein	Differential centrifugation	Microvesicles
428	Vesiclepedia_1192	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
429	Vesiclepedia_728	25359493	Homo sapiens	Proteomic signatures of extracellular vesicles secreted by nonmineralizing and mineralizing human osteoblasts and stimulation of tumor cell growth.	Osteoblasts	Protein	Differential centrifugation Ultracentrifugation	Matrix vesicles
430	Vesiclepedia_1010	23185418	Homo sapiens	Improved flow cytometric assessment reveals distinct microvesicle (cell-derived microparticle) signatures in joint diseases.	Synovial fluid	Protein	Filtration Ultracentrifugation	Microvesicles
431	Vesiclepedia_65	19415654	Homo sapiens	Proteomics of MUC1-containing lipid rafts from plasma membranes and exosomes of human breast carcinoma cells MCF-7.	Breast cancer cells	Protein	Differential centrifugation Sucrose density gradient	Exosomes
432	Vesiclepedia_876	29955024	Homo sapiens	Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells	Embryonic kidney cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
433	Vesiclepedia_1216	27872147	Rattus norvegicus	Primary Human and Rat .-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity.	Islets	Protein	Differential centrifugation Ultracentrifugation	Exosomes
434	Vesiclepedia_444	22418980	Homo sapiens	A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.	Urine	Protein	-	Exosomes
435	Vesiclepedia_669	29953960	Homo sapiens	Exosomes derived from calcium oxalate-exposed macrophages enhance IL-8 production from renal cells, neutrophil migration and crystal invasion through extracellular matrix.	Macrophages	Protein	Microfiltration Differential centrifugation Ultracentrifugation	Exosomes
436	Vesiclepedia_6	11306949	Mus musculus	Nonspecific B and T cell-stimulatory activity mediated by mast cells is associated with exosomes.	Mast cells	Protein	-	Exosomes
437	Vesiclepedia_191	21635979	Mus musculus	Proteomic characterization of thymocyte-derived microvesicles and apoptotic bodies in BALB/c mice	Thymus	Protein	Differential centrifugation Filtration	Microvesicles
438	Vesiclepedia_157	21630462	Homo sapiens	Proteomic analysis of microvesicles derived from human colorectal cancer ascites	Ascites	Protein	Differential centrifugation Sucrose density gradient OptiPrep density gradient	Microvesicles
439	Vesiclepedia_389	18819103	Homo sapiens	Structural heterogeneity and protein composition of exosome-like vesicles (prostasomes) in human semen.	Seminal fluid	Protein	-	Exosomes/Prostasomes
440	Vesiclepedia_223	10393703	Homo sapiens	In vitro generation of endothelial microparticles and possible prothrombotic activity in patients with lupus anticoagulant	Endothelial cells	Protein	Differential centrifugation Ultracentrifugation	Microparticles
441	Vesiclepedia_64	18520029	Homo sapiens	Exosome-like vesicles with dipeptidyl peptidase IV in human saliva.	Saliva	Protein	Filtration Diafiltration Gel filtration	Exosomes
442	Vesiclepedia_670	29953960	Homo sapiens	Exosomes derived from calcium oxalate-exposed macrophages enhance IL-8 production from renal cells, neutrophil migration and crystal invasion through extracellular matrix.	Macrophages	Protein	Microfiltration Differential centrifugation Ultracentrifugation	Exosomes
443	Vesiclepedia_170	21859146	Homo sapiens	Identification of a conserved glycan signature for microvesicles	Colorectal cancer cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Microvesicles
444	Vesiclepedia_827	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Filtration Ultracentrifugation Sucrose density gradient	Exosomes
445	Vesiclepedia_751	29988836	Homo sapiens	Ultrafiltration and size exclusion chromatography combined with asymmetrical-flow field-flow fractionation for the isolation and characterisation of extracellular vesicles from urine	Urine	Protein	Filtration Size exclusion chromatography	Extracellular vesicles
446	Vesiclepedia_30	16446100	Rattus norvegicus	Exosomes are released by cultured cortical neurones.	Cortical neurones	Protein	Differential centrifugation Sucrose density gradient	Exosomes
447	Vesiclepedia_976	22808001	Homo sapiens	Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment.	Serum	Protein	Filtration ExoQuick	Exosomes
448	Vesiclepedia_219	10694520	Homo sapiens	Elevated levels of shed membrane microparticles with procoagulant potential in the peripheral circulating blood of patients with acute coronary syndromes	Plasma	Protein	Immunoaffinity [Annexin-V]	Microparticles
449	Vesiclepedia_765	29953723	Salmo salar	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Leukocytes	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
450	Vesiclepedia_1066	29963299	Homo sapiens	Enrichment of extracellular vesicles from human synovial fluid using size exclusion chromatography.	Synovial fluid	Protein	Size exclusion chromatography	Extracellular vesicles
451	Vesiclepedia_1133	23861904	Homo sapiens	Exosomal signaling during hypoxia mediates microvascular endothelial cell migration and vasculogenesis.	Placental mesenchymal stem cells	Protein	Differential centrifugation Ultracentrifugation Ultrafiltration Density gradient centrifugation	Exosomes
452	Vesiclepedia_695	28842968	Homo sapiens	Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles.	Colorectal cancer cells	Protein	Differential centrifugation Ultracentrifugation	Microvesicles
453	Vesiclepedia_44	19028452	Homo sapiens	Proteomic profiling of human plasma exosomes identifies PPARgamma as an exosome-associated protein.	Plasma	Protein	Filtration Size exclusion chromatography Sucrose density gradient	Exosomes
454	Vesiclepedia_229	2942561	Homo sapiens	Platelet surface glycoproteins. Studies on resting and activated platelets and platelet membrane microparticles in normal subjects, and observations in patients during adult respiratory distress syndrome and cardiac surgery	Plasma	Protein	Differential centrifugation	Microparticles
455	Vesiclepedia_964	25844599	Homo sapiens	Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
456	Vesiclepedia_545	23983189	Homo sapiens	Characterization of Multiple Myeloma Vesicles by Label-Free Relative Quantitation.	B cells	Protein	-	Exosomes/Extracellular vesicles/Microvesicles
457	Vesiclepedia_520	23601281	Homo sapiens	Proteomic characterization of human platelet-derived microparticles.	Platelets	Protein	-	Microparticles
458	Vesiclepedia_304	17478559	Mus musculus	Identification and characterization of microvesicles secreted by 3T3-L1 adipocytes: redox- and hormone-dependent induction of milk fat globule-epidermal growth 8-associated microvesicles	Adipocytes	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Microvesicles
459	Vesiclepedia_1025	22327366	Homo sapiens	Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs.	Vascular endothelial cells	Protein miRNA	Differential centrifugation Ultracentrifugation	Extracellular vesicles
460	Vesiclepedia_776	29953723	Salmo salar	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Leukocytes	Protein	Differential centrifugation	Microvesicles
461	Vesiclepedia_925	25483805	Homo sapiens	Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties	Embryonic kidney cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
462	Vesiclepedia_1262	24371517	Homo sapiens	Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients.	Urine	Protein	Differential centrifugation Ultracentrifugation	Exosomes
463	Vesiclepedia_38	15210972	Oryctolagus cuniculus	Cells release prions in association with exosomes.	Epithelial cells	Protein	Differential centrifugation Sucrose density gradient	Exosomes
464	Vesiclepedia_863	22046311	Mus musculus	Exosomes from Plasmodium yoelii-infected reticulocytes protect mice from lethal infections	Plasma	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
465	Vesiclepedia_443	22329422	Homo sapiens	Quantitative proteome profiling of normal human circulating microparticles.	Plasma	Protein	-	Microparticles
466	Vesiclepedia_910	28687758	Sus scrofa	Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers	Polarised retinal pigmented epithelial cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
467	Vesiclepedia_777	29953723	Salmo salar	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Leukocytes	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
468	Vesiclepedia_513	23533145	Homo sapiens	In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.	Urine	Protein	-	Exosomes/Microvesicles
469	Vesiclepedia_134	15304316	Rattus norvegicus	PLD2 is enriched on exosomes and its activity is correlated to the release of exosomes	Basophilic leukemia cells	Protein Lipids	Differential centrifugation	Exosomes
470	Vesiclepedia_187	22116803	Equus caballus	Cell-Secreted Vesicles in Equine Ovarian Follicular Fluid Contain miRNAs and Proteins: A Possible New Form of Cell Communication Within the Ovarian Follicle	Serum	Protein	Differential centrifugation ExoQuick	Exosomes
471	Vesiclepedia_1230	25503107	Homo sapiens	Tumor-derived microvesicles mediate human breast cancer invasion through differentially glycosylated EMMPRIN.	Breast cancer cells	Protein	Ultracentrifugation Filtration Density gradient centrifugation	Microvesicles
472	Vesiclepedia_1083	25104112	Homo sapiens	Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy.	Plasma	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Exosomes
473	Vesiclepedia_590	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Colorectal cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
474	Vesiclepedia_293	10415024	Homo sapiens	Activated human T cells release bioactive Fas ligand and APO2 ligand in microvesicles	T cells	Protein	Differential centrifugation Ultracentrifugation FACS	Microvesicles
475	Vesiclepedia_620	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Melanoma cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
476	Vesiclepedia_892	24946052	Homo sapiens	Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment	Lung cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
477	Vesiclepedia_212	21372807	Rattus norvegicus	Upregulation of lipid synthesis in small rat adipocytes by microvesicle-associated CD73 from large adipocytes	Adipocytes	Protein	Differential centrifugation	Microvesicles
478	Vesiclepedia_629	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Ovarian cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
479	Vesiclepedia_34	19190083	Homo sapiens	Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense.	Tracheobronchial cells	Protein mRNA	Differential centrifugation Filtration Sucrose density gradient	Exosomes
480	Vesiclepedia_901	26100252	Homo sapiens	Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts	Chronic lymphocytic leukemia cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
481	Vesiclepedia_1126	24295599	Mus musculus	Exosomes from myeloid-derived suppressor cells carry biologically active proteins.	Myeloid-derived suppressor cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
482	Vesiclepedia_764	29953723	Salmo salar	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Leukocytes	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
483	Vesiclepedia_355	24115447	Homo sapiens	Comparative proteomics evaluation of plasma exosome isolation techniques and assessment of the stability of exosomes in normal human blood plasma	Plasma	Protein	Differential centrifugation Filtration Ultracentrifugation Immunoaffinity (EpCAM)	Exosomes
484	Vesiclepedia_540	23886663	Homo sapiens	LRRK2 Secretion in Exosomes is Regulated by 14-3-3.	Urine	Protein	-	Exosomes/Microvesicles
485	Vesiclepedia_334	20976003	Homo sapiens	Selective release of microRNA species from normal and malignant mammary epithelial cells	Breast cancer cells	Protein miRNA	Differential centrifugation Filtration	Exosomes
486	Vesiclepedia_1061	30006486	Homo sapiens	The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells.	Astrocytoma cells	Protein	Filtration Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
487	Vesiclepedia_308	16342139	Homo sapiens	Proteomic analysis of malignant lymphocyte membrane microparticles using double ionization coverage optimization	B cells	Protein	Differential centrifugation	Microparticles
488	Vesiclepedia_820	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Differential centrifugation Filtration ExoQuick Ultracentrifugation	Exosomes
489	Vesiclepedia_628	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Ovarian cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
490	Vesiclepedia_66	19199708	Homo sapiens	Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).	Saliva	Protein	Differential centrifugation	Exosomes
491	Vesiclepedia_1064	30006486	Homo sapiens	The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells.	Astrocytoma cells	Protein	Filtration Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
492	Vesiclepedia_374	18039940	Cryptococcus neoformans	Extracellular vesicles produced by Cryptococcus neoformans contain protein components associated with virulence.	Cryptococcus neoformans	Protein	-	Exosomes/Extracellular vesicles
493	Vesiclepedia_1142	23454749	Homo sapiens	BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression.	Bone marrow mesenchymal stromal cells	Protein	Differential centrifugation Ultracentrifugation Filtration ExoQuick	Exosomes
494	Vesiclepedia_979	25471885	Drosophila melanogaster	The ESCRT machinery regulates the secretion and long-range activity of Hedgehog.	Drosophila wing imaginal Disc	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
495	Vesiclepedia_489	23260141	Mus musculus	Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.	Fibroblasts	Protein	-	Exosomes
496	Vesiclepedia_1098	24513287	Mus musculus	Lipid synthesis is promoted by hypoxic adipocyte-derived exosomes in 3T3-L1 cells.	adipocytes	Protein	Differential centrifugation Ultracentrifugation Filtration	Exosomes
497	Vesiclepedia_664	29956871	Homo sapiens	Expression analysis of extracellular microRNA in bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis	Bronchoalveolar lavage fluid	Protein	Differential centrifugation Ultracentrifugation Filtration	Microvesicles
498	Vesiclepedia_662	29956871	Homo sapiens	Expression analysis of extracellular microRNA in bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis	Bronchoalveolar lavage fluid	Protein	Differential centrifugation Ultracentrifugation Filtration	Microvesicles
499	Vesiclepedia_416	20687614	Myxococcus xanthus	Profiling the outer membrane proteome during growth and development of the social bacterium Myxococcus xanthus by selective biotinylation and analyses of outer membrane vesicles.	Myxococcus xanthus	Protein	-	Membrane vesicles
500	Vesiclepedia_572	26858453	Homo sapiens	Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes	Dendritic cells	Protein	Differential centrifugation Ultracentrifugation Immunobeads (CD81 PD)	Extracellular vesicles
501	Vesiclepedia_423	21138299	Francisella tularensis	Proteomic characterization and functional analysis of outer membrane vesicles of Francisella novicida suggests possible role in virulence and use as a vaccine.	Francisella tularensis	Protein	-	Membrane vesicles
502	Vesiclepedia_525	23658846	Mus musculus	Immunomodulatory impact of leishmania-induced macrophage exosomes: a comparative proteomic and functional analysis.	Macrophages	Protein	-	Exosomes
503	Vesiclepedia_173	21859146	Homo sapiens	Identification of a conserved glycan signature for microvesicles	Breast milk	Protein	Differential centrifugation Filtration Ultracentrifugation	Microvesicles
504	Vesiclepedia_490	23264574	Francisella novicida	Production of Outer Membrane Vesicles and Outer Membrane Tubes by Francisella novicida.	Francisella novicida	Protein	-	Membrane vesicles
505	Vesiclepedia_218	10694520	Homo sapiens	Elevated levels of shed membrane microparticles with procoagulant potential in the peripheral circulating blood of patients with acute coronary syndromes	Plasma	Protein	Immunoaffinity [Annexin-V]	Microparticles
506	Vesiclepedia_75	19381331	Homo sapiens	High levels of exosomes expressing CD63 and caveolin-1 in plasma of melanoma patients.	Plasma	Protein	Differential centrifugation	Exosomes
507	Vesiclepedia_498	23376485	Homo sapiens	Proteomic analysis of podocyte exosome-enriched fraction from normal human urine.	Urine	Protein	-	Exosomes/Membrane vesicles
508	Vesiclepedia_951	27601599	Homo sapiens	Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components.	Breast milk	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
509	Vesiclepedia_819	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Differential centrifugation Filtration ExoQuick Ultracentrifugation	Exosomes
510	Vesiclepedia_1306	-	Saccharomyces cerevisiae	Extracellular vesicles secreted by Saccharomyces cerevisiae are involved in cell wall remodelling	Saccharomyces cerevisiae	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
511	Vesiclepedia_858	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer	Plasma	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
512	Vesiclepedia_115	21505438	Homo sapiens	Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells.	T cells	Protein miRNA	Differential centrifugation Filtration Ultracentrifugation	Exosomes
513	Vesiclepedia_250	9396452	Homo sapiens	Cell-derived microparticles generated in patients during cardiopulmonary bypass are highly procoagulant	Plasma	Protein Lipids	Differential centrifugation	Microparticles
514	Vesiclepedia_871	24614226	Ovis aries	Extracellular vesicles in luminal fluid of the ovine uterus	Uterine luminal fluid	Protein	Differential centrifugation Filtration ExoQuick	Extracellular vesicles
515	Vesiclepedia_536	23818640	Homo sapiens	Modulation of B-cell exosome proteins by gamma herpesvirus infection.	B cells	Protein	-	Exosomes/Microvesicles/Oncosomes/Microparticles
516	Vesiclepedia_836	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Differential centrifugation Filtration ExoQuick Ultracentrifugation	Exosomes
517	Vesiclepedia_387	18563738	Homo sapiens	Comparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles.	Endothelial cells	Protein	-	Microparticles
518	Vesiclepedia_811	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Differential centrifugation Filtration ExoQuick Ultracentrifugation	Exosomes
519	Vesiclepedia_396	19413345	Homo sapiens	Proteomic analysis of malignant B-cell derived microparticles reveals CD148 as a potentially useful antigenic biomarker for mantle cell lymphoma diagnosis.	B cells	Protein	-	Microparticles
520	Vesiclepedia_1264	24371517	Homo sapiens	Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients.	Urine	Protein	Differential centrifugation Ultracentrifugation	Exosomes
521	Vesiclepedia_963	25844599	Homo sapiens	Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
522	Vesiclepedia_663	29956871	Homo sapiens	Expression analysis of extracellular microRNA in bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis	Bronchoalveolar lavage fluid	Protein	Differential centrifugation Ultracentrifugation Filtration	Exosomes
523	Vesiclepedia_1041	27770278	Homo sapiens	Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease.	Glioblastoma cells	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Extracellular vesicles
524	Vesiclepedia_899	26100252	Homo sapiens	Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts	Chronic lymphocytic leukemia cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
525	Vesiclepedia_267	12757771	Homo sapiens	Endothelial cells release phenotypically and quantitatively distinct microparticles in activation and apoptosis	Endothelial cells	Protein	Differential centrifugation FACS	Microparticles
526	Vesiclepedia_32	18452139	Homo sapiens	Primary human keratinocytes externalize stratifin protein via exosomes.	Keratinocytes	Protein	Differential centrifugation Sucrose density gradient Diafiltration	Exosomes
527	Vesiclepedia_1109	24391718	Homo sapiens	Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.	Prostate epithelial cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
528	Vesiclepedia_1248	24939845	Homo sapiens	Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein.	Leukemia cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
529	Vesiclepedia_376	18346024	Homo sapiens	The proteome of red cell membranes and vesicles during storage in blood bank conditions.	Red blood cells	Protein	-	Microvesicles/Nanovesicles
530	Vesiclepedia_119	21362503	Homo sapiens	Protein profile of exosomes from trabecular meshwork cells.	Urine	Protein	Differential centrifugation Sucrose density gradient	Exosomes
531	Vesiclepedia_52	14975938	Homo sapiens	Proteomic analysis of exosomes isolated from human malignant pleural effusions.	Malignant pleural effusions	Protein	Differential centrifugation Sucrose density gradient	Exosomes
532	Vesiclepedia_1209	29127410	Homo sapiens	Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies.	Bronchial epithelial cells	Protein	Ultrafiltration Size exclusion chromatography	Extracellular vesicles
533	Vesiclepedia_1136	23861904	Homo sapiens	Exosomal signaling during hypoxia mediates microvascular endothelial cell migration and vasculogenesis.	Placental mesenchymal stem cells	Protein	Differential centrifugation Ultracentrifugation Ultrafiltration Density gradient centrifugation	Exosomes
534	Vesiclepedia_1211	29127410	Homo sapiens	Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies.	Bronchial epithelial cells	Protein	Ultrafiltration Size exclusion chromatography	Extracellular vesicles
535	Vesiclepedia_1229	26154623	Homo sapiens	Size-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals	Plasma	Protein	Size exclusion chromatography	Extracellular vesicles
536	Vesiclepedia_1076	25104112	Homo sapiens	Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy.	Plasma	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Exosomes
537	Vesiclepedia_1073	25104112	Homo sapiens	Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy.	Plasma	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Exosomes
538	Vesiclepedia_401	19548909	Homo sapiens	Differential stimulation of monocytic cells results in distinct populations of microparticles.	Monocytes	Protein	-	Microparticles
539	Vesiclepedia_929	25483805	Gallus gallus	Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties	Notochord cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
540	Vesiclepedia_896	26100252	Homo sapiens	Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts	Chronic lymphocytic leukemia cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
541	Vesiclepedia_705	28811610	Homo sapiens	Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA.	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Microvesicles/Apoptotic bodies
542	Vesiclepedia_89	20424270	Rattus norvegicus	Exosomes account for vesicle-mediated transcellular transport of activatable phospholipases and prostaglandins.	Basophilic leukemia cells	Protein Lipids	Differential centrifugation Sucrose density gradient	Exosomes
543	Vesiclepedia_594	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Kidney cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
544	Vesiclepedia_380	18346024	Homo sapiens	The proteome of red cell membranes and vesicles during storage in blood bank conditions.	Red blood cells	Protein	-	Microvesicles/Nanovesicles
545	Vesiclepedia_116	21505438	Homo sapiens	Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells.	B cells	Protein miRNA	Differential centrifugation Filtration Ultracentrifugation	Exosomes
546	Vesiclepedia_21	19837982	Homo sapiens	Proteomic and bioinformatic analysis of immunoaffinity-purified exosomes derived from the human colon tumor cell line LIM1215.	Colorectal cancer cells	Protein	Filtration Ultracentrifugation Sucrose density gradient	Exosomes
547	Vesiclepedia_113	21557262	Homo sapiens	Proteomic identification of exosomal LRG1: A potential urinary biomarker for detecting NSCLC.	Urine	Protein	Differential centrifugation Ultracentrifugation	Exosomes
548	Vesiclepedia_1074	25104112	Homo sapiens	Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy.	Plasma	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Exosomes
549	Vesiclepedia_801	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Embryonic kidney cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
550	Vesiclepedia_805	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
551	Vesiclepedia_600	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Kidney cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
552	Vesiclepedia_299	12796750	Homo sapiens	High levels of circulating endothelial microparticles in patients with acute coronary syndromes	Plasma	Protein	Differential centrifugation FACS	Microparticles
553	Vesiclepedia_1289	19912576	Homo sapiens	HIV Nef is secreted in exosomes and triggers apoptosis in bystander CD4+ T cells.	Cervix carcinoma cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
554	Vesiclepedia_800	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Embryonic kidney cells	Protein	Differential centrifugation	Microvesicles
555	Vesiclepedia_1137	23861904	Homo sapiens	Exosomal signaling during hypoxia mediates microvascular endothelial cell migration and vasculogenesis.	Placental mesenchymal stem cells	Protein	Differential centrifugation Ultracentrifugation Ultrafiltration Density gradient centrifugation	Exosomes
556	Vesiclepedia_993	24434149	Homo sapiens	In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome.	Ovarian cancer cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
557	Vesiclepedia_314	15499615	Homo sapiens	Microvesicles derived from activated platelets induce metastasis and angiogenesis in lung cancer	Lung cancer cells	Protein	Differential centrifugation FACS	Microvesicles
558	Vesiclepedia_627	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Ovarian cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
559	Vesiclepedia_104	21763319	Homo sapiens	Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells.	Pancreatic adenocarcinoma cells	Protein	Differential centrifugation Filtration Ultrafiltration Ultracentrifugation	Exosomes
560	Vesiclepedia_598	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Kidney cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
561	Vesiclepedia_28	19109410	Homo sapiens	Proteomic and immunologic analyses of brain tumor exosomes.	Glioma cells	Protein	Differential centrifugation Sucrose density gradient	Exosomes
562	Vesiclepedia_1166	29904572	Bos taurus	A subset of extracellular vesicles carries the bulk of microRNAs in commercial dairy cow's milk.	Bovine milk	Protein miRNA	Differential centrifugation Density gradient centrifugation	Extracellular vesicles
563	Vesiclepedia_373	17787032	Escherichia coli	Global proteomic profiling of native outer membrane vesicles derived from Escherichia coli.	Escherichia coli	Protein	-	Membrane vesicles
564	Vesiclepedia_845	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
565	Vesiclepedia_1269	24218614	Homo sapiens	Unexpected gain of function for the scaffolding protein plectin due to mislocalization in pancreatic cancer.	Pancreatic adenocarcinoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
566	Vesiclepedia_847	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
567	Vesiclepedia_143	22723089	Homo sapiens	Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes.	Prostate cancer cells	Protein	Sucrose density gradient	Exosomes
568	Vesiclepedia_843	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
569	Vesiclepedia_258	9126269	Homo sapiens	Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations	Leukemia cells	Protein	Differential centrifugation Sucrose density gradient	Microvesicles
570	Vesiclepedia_1036	29887978	Homo sapiens	Evaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing.	Serum	Protein miRNA	Exo-spin	Extracellular vesicles
571	Vesiclepedia_563	26858453	Homo sapiens	Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes	Dendritic cells	Protein	Differential centrifugation Ultracentrifugation OptiPrep density gradient	Microvesicles
572	Vesiclepedia_1022	19665478	Salmo salar	CpG-induced secretion of MHCIIbeta and exosomes from salmon (Salmo salar) APCs.	Head kidney leukocytes	Protein	Differential centrifugation Ultracentrifugation	Exosomes
573	Vesiclepedia_177	19567368	Homo sapiens	Proteomics characterization of cell membrane blebs in human retinal pigment epithelium cells	Epithelial cells	Protein	Differential centrifugation	Membrane blebs
574	Vesiclepedia_35	19367702	Rattus norvegicus	Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.	Hepatocytes	Protein	Differential centrifugation Filtration Sucrose density gradient	Exosomes
575	Vesiclepedia_1031	29887978	Homo sapiens	Evaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing.	Serum	Protein miRNA	exoEasy columns	Extracellular vesicles
576	Vesiclepedia_761	29953723	Salmo salar	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Leukocytes	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
577	Vesiclepedia_1164	29904572	Bos taurus	A subset of extracellular vesicles carries the bulk of microRNAs in commercial dairy cow's milk.	Bovine milk	Protein miRNA	Differential centrifugation Density gradient centrifugation	Extracellular vesicles
578	Vesiclepedia_889	24946052	Homo sapiens	Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment	Lung cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
579	Vesiclepedia_977	22808001	Homo sapiens	Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment.	Serum	Protein	Filtration ExoQuick	Exosomes
580	Vesiclepedia_823	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Filtration Ultracentrifugation Sucrose density gradient	Exosomes
581	Vesiclepedia_251	9396452	Homo sapiens	Cell-derived microparticles generated in patients during cardiopulmonary bypass are highly procoagulant	Plasma	Protein Lipids	Differential centrifugation	Microparticles
582	Vesiclepedia_73	18494037	Mus musculus	Difference gel electrophoresis analysis of Ras-transformed fibroblast cell-derived exosomes.	Embryonic fibroblasts	Protein	Differential centrifugation	Exosomes
583	Vesiclepedia_379	18346024	Homo sapiens	The proteome of red cell membranes and vesicles during storage in blood bank conditions.	Red blood cells	Protein	-	Microvesicles/Nanovesicles
584	Vesiclepedia_567	26858453	Homo sapiens	Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes	Dendritic cells	Protein	Differential centrifugation Ultracentrifugation Immunobeads (Igg1 FT)	Extracellular vesicles
585	Vesiclepedia_1225	26154623	Homo sapiens	Size-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals	Plasma	Protein	Exo-spin	Extracellular vesicles
586	Vesiclepedia_132	19188015	Homo sapiens	Systemic presence and tumor-growth promoting effect of ovarian carcinoma released exosomes	Ovarian cancer cells	Protein Lipids	Differential centrifugation Sucrose density gradient	Exosomes
587	Vesiclepedia_849	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
588	Vesiclepedia_136	22723089	Homo sapiens	Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes.	Prostate cancer cells	Protein	Sucrose density gradient	Exosomes
589	Vesiclepedia_937	29207636	Homo sapiens	Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer.	Urine	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
590	Vesiclepedia_835	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Differential centrifugation Filtration ExoQuick Ultracentrifugation	Exosomes
591	Vesiclepedia_1242	25261722	Homo sapiens	Inflammatory cytokines, interleukin-1 beta and tumor necrosis factor-alpha, upregulated in glioblastoma multiforme, raise the levels of CRYAB in exosomes secreted by U373 glioma cells.	Glioblastoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
592	Vesiclepedia_168	21859146	Homo sapiens	Identification of a conserved glycan signature for microvesicles	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Microvesicles
593	Vesiclepedia_815	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Differential centrifugation Filtration ExoQuick Ultracentrifugation	Exosomes
594	Vesiclepedia_268	12757771	Homo sapiens	Endothelial cells release phenotypically and quantitatively distinct microparticles in activation and apoptosis	Endothelial cells	Protein	Differential centrifugation FACS	Microparticles
595	Vesiclepedia_228	2942561	Homo sapiens	Platelet surface glycoproteins. Studies on resting and activated platelets and platelet membrane microparticles in normal subjects, and observations in patients during adult respiratory distress syndrome and cardiac surgery	Serum	Protein	Differential centrifugation	Microparticles
596	Vesiclepedia_146	22723089	Homo sapiens	Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes.	Prostate cancer cells	Protein	Sucrose density gradient	Exosomes
597	Vesiclepedia_1008	23463506	Homo sapiens	The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes.	T cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
598	Vesiclepedia_854	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
599	Vesiclepedia_542	23935504	Homo sapiens	A Novel Role for Pro-Coagulant Microvesicles in the Early Host Defense against Streptococcus pyogenes.	Peripheral blood mononucelar cells	Protein	-	Microvesicles
600	Vesiclepedia_426	21386968	Acinetobacter baumannii	Acinetobacter baumannii secretes cytotoxic outer membrane protein A via outer membrane vesicles.	Acinetobacter baumannii	Protein	-	Membrane vesicles
601	Vesiclepedia_704	28811610	Homo sapiens	Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA.	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Microvesicles/Apoptotic bodies
602	Vesiclepedia_51	14975938	Homo sapiens	Proteomic analysis of exosomes isolated from human malignant pleural effusions.	Malignant pleural effusions	Protein	Differential centrifugation Sucrose density gradient	Exosomes
603	Vesiclepedia_12	15478216	Homo sapiens	Proteomic analysis of melanoma-derived exosomes by two-dimensional polyacrylamide gel electrophoresis and mass spectrometry.	Melanoma cells	Protein	Filtration Ultracentrifugation Sucrose density gradient	Exosomes
604	Vesiclepedia_1252	24939845	Homo sapiens	Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein.	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
605	Vesiclepedia_391	19327352	Bos taurus	Anchorage-independent growth of breast carcinoma cells is mediated by serum exosomes.	Serum	Protein	-	Exosomes
606	Vesiclepedia_865	22046311	Mus musculus	Exosomes from Plasmodium yoelii-infected reticulocytes protect mice from lethal infections	Reticulocytes	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
607	Vesiclepedia_1104	24391718	Homo sapiens	Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.	Prostate epithelial cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
608	Vesiclepedia_33	21136642	Mus musculus	Oligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons?	Oligodendrocytes	Protein	Differential centrifugation Sucrose density gradient	Exosomes
609	Vesiclepedia_309	17536014	Homo sapiens	Endothelial progenitor cell derived microvesicles activate an angiogenic program in endothelial cells by a horizontal transfer of Mrna	Endothelial cells	Protein mRNA	Differential centrifugation Ultracentrifugation FACS	Microvesicles
610	Vesiclepedia_691	28170197	Homo sapiens	Enhanced Cardioprotection by Human Endometrium Mesenchymal Stem Cells Driven by Exosomal MicroRNA-21	Endometrium-derived mesenchymal stem cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
611	Vesiclepedia_1003	23785420	Bos taurus	CD9-positive microvesicles mediate the transfer of molecules to Bovine Spermatozoa during epididymal maturation.	Epididymal fluid	Protein	Differential centrifugation Ultracentrifugation Immunoaffinity [CD9]	Microvesicles
612	Vesiclepedia_1186	28326167	Homo sapiens	Residual urinary extracellular vesicles in ultracentrifugation supernatants after hydrostatic filtration dialysis enrichment.	Urine	Protein	Hydrostatic filtration dialysis Differential centrifugation Ultracentrifugation	Extracellular vesicles
613	Vesiclepedia_631	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Ovarian cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
614	Vesiclepedia_1223	26154623	Homo sapiens	Size-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals	Plasma	Protein	Exo-spin	Extracellular vesicles
615	Vesiclepedia_50	14582906	Homo sapiens	Exosomes with major histocompatibility complex class II and co-stimulatory molecules are present in human BAL fluid.	Dendritic cells	Protein	Differential centrifugation Immunobeads (EpCAM)	Exosomes
616	Vesiclepedia_1002	24211404	Mus musculus	Induction of pulmonary hypertensive changes by extracellular vesicles from monocrotaline-treated mice.	Lung tissue	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
617	Vesiclepedia_1268	24218614	Homo sapiens	Unexpected gain of function for the scaffolding protein plectin due to mislocalization in pancreatic cancer.	Pancreatic adenocarcinoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
618	Vesiclepedia_573	26858453	Homo sapiens	Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes	Dendritic cells	Protein	Differential centrifugation Ultracentrifugation Immunobeads (CD81 FT)	Extracellular vesicles
619	Vesiclepedia_596	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Kidney cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
620	Vesiclepedia_202	21601655	Homo sapiens	Sizing and phenotyping of cellular vesicles using Nanoparticle Tracking Analysis	Placenta	Protein	Differential centrifugation Ultracentrifugation	Microvesicles
621	Vesiclepedia_154	21966536	Mus musculus	Leukocyte- and platelet-derived microvesicle interactions following in vitro and in vivo activation of toll-like receptor 4 by lipopolysaccharide	Plasma	Protein	Differential centrifugation Filtration	Microvesicles
622	Vesiclepedia_1024	22327366	Homo sapiens	Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs.	Vascular endothelial cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
623	Vesiclepedia_784	29953723	Salmo salar	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Leukocytes	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
624	Vesiclepedia_95	21828046	Rattus norvegicus	The proteo-lipidic composition of exosomes changes during reticulocyte maturation.	Reticulocytes	Protein Lipids	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
625	Vesiclepedia_692	28170197	Homo sapiens	Enhanced Cardioprotection by Human Endometrium Mesenchymal Stem Cells Driven by Exosomal MicroRNA-21	Adipose-derived mesenchymal stem cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
626	Vesiclepedia_448	22448133	Pseudomonas aeruginosa	Vesiculation from Pseudomonas aeruginosa under SOS.	Pseudomonas aeruginosa	Protein	-	Membrane vesicles
627	Vesiclepedia_266	18425114	Mus musculus	Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells	Plasma	Protein	Differential centrifugation Ultracentrifugation	Microvesicles
628	Vesiclepedia_1249	24939845	Homo sapiens	Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein.	Leukemia cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
629	Vesiclepedia_1106	24391718	Homo sapiens	Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.	Prostate epithelial cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
630	Vesiclepedia_814	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Differential centrifugation Filtration ExoQuick Ultracentrifugation	Exosomes
631	Vesiclepedia_1270	24218614	Homo sapiens	Unexpected gain of function for the scaffolding protein plectin due to mislocalization in pancreatic cancer.	Pancreatic adenocarcinoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
632	Vesiclepedia_859	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer	Plasma	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
633	Vesiclepedia_1212	29127410	Homo sapiens	Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies.	Bronchial epithelial cells	Protein	Ultracentrifugation	Extracellular vesicles
634	Vesiclepedia_1096	24976626	Homo sapiens	Exosomal transfer from human renal proximal tubule cells to distal tubule and collecting duct cells.	Renal proximal tubule cells	Protein	Differential centrifugation Ultracentrifugation Immunoaffinity	Exosomes
635	Vesiclepedia_1313	-	Saccharomyces cerevisiae	Extracellular vesicles secreted by Saccharomyces cerevisiae are involved in cell wall remodelling	Saccharomyces cerevisiae	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
636	Vesiclepedia_722	25802036	Homo sapiens	Glioblastoma-derived extracellular vesicles modify the phenotype of monocytic cells.	Glioblastoma cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
637	Vesiclepedia_760	29953723	Salmo salar	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Leukocytes	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
638	Vesiclepedia_1254	24468161	Homo sapiens	Molecular characterization of exosome-like vesicles from breast cancer cells.	Breast cancer cells	Protein miRNA	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
639	Vesiclepedia_70	19812188	Rattus norvegicus	Immature dendritic cell-derived exosomes rescue septic animals via milk fat globule epidermal growth factor VIII.	Dendritic cells	Protein	Differential centrifugation	Exosomes
640	Vesiclepedia_307	16342139	Homo sapiens	Proteomic analysis of malignant lymphocyte membrane microparticles using double ionization coverage optimization	T cells	Protein	Differential centrifugation	Microparticles
641	Vesiclepedia_983	25367658	Candida albicans	Proteomics unravels extracellular vesicles as carriers of classical cytoplasmic proteins in Candida albicans.	Candida albicans	Protein	Differential centrifugation Ultracentrifugation Filtration	Extracellular vesicles
642	Vesiclepedia_618	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Melanoma cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
643	Vesiclepedia_680	29148239	Homo sapiens	Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants.	Umblical cord mesenchymal stem cells	Protein	Differential centrifugation Ultracentrifugation Sonication Filtration	Microvesicles
644	Vesiclepedia_687	29148239	Homo sapiens	Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants.	Umblical cord mesenchymal stem cells	Protein	Differential centrifugation Ultracentrifugation Sonication Filtration	Microvesicles
645	Vesiclepedia_419	21136642	Mus musculus	Oligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons?	Oligodendrocytes	Protein	-	Exosomes
646	Vesiclepedia_151	22075275	Homo sapiens	Methodology for isolation, identification and characterization of microvesicles in peripheral blood	Plasma	Protein	Differential centrifugation Filtration Ultracentrifugation	Microvesicles
647	Vesiclepedia_1094	25065644	Homo sapiens	Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells.	Duodenal cancer cells	Protein	Differential centrifugation Filtration Ultrafiltration	Exosomes
648	Vesiclepedia_956	27601599	Homo sapiens	Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components.	Breast milk	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
649	Vesiclepedia_783	29953723	Salmo salar	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Leukocytes	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
650	Vesiclepedia_718	26148937	Homo sapiens	Proteomics profiling of cholangiocarcinoma exosomes: A potential role of oncogenic protein transferring in cancer progression.	Cholangiocarcinoma cells	Protein	Differential centrifugation Ultracentrifugation Filtration	Exosomes
651	Vesiclepedia_1006	23463506	Mus musculus	The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes.	T cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
652	Vesiclepedia_302	1321158	Rattus norvegicus	Membrane anchoring of the autoantigen GAD65 to microvesicles in pancreatic beta-cells by palmitoylation in the NH2-terminal domain.	Pancreatic cells	Protein	Differential centrifugation	Microvesicles
653	Vesiclepedia_235	10648405	Homo sapiens	Cellular origin and procoagulant properties of microparticles in meningococcal sepsis	Plasma	Protein	Differential centrifugation FACS	Microparticles
654	Vesiclepedia_953	27601599	Homo sapiens	Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components.	Breast milk	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
655	Vesiclepedia_1193	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
656	Vesiclepedia_715	28811610	Homo sapiens	Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA.	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Apoptotic bodies
657	Vesiclepedia_1122	24347249	Homo sapiens	Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation ExoQuick	Exosomes
658	Vesiclepedia_257	9126269	Homo sapiens	Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations	Leukemia cells	Protein	Differential centrifugation Sucrose density gradient	Microvesicles
659	Vesiclepedia_1191	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
660	Vesiclepedia_959	26196085	Homo sapiens	Identification of prostate cancer biomarkers in urinary exosomes.	Urine	Protein	Differential centrifugation Ultracentrifugation Filtration	Exosomes
661	Vesiclepedia_911	28687758	Sus scrofa	Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers	Polarised retinal pigmented epithelial cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
662	Vesiclepedia_422	21138299	Francisella philomiragia	Proteomic characterization and functional analysis of outer membrane vesicles of Francisella novicida suggests possible role in virulence and use as a vaccine.	Francisella philomiragia	Protein	-	Membrane vesicles
663	Vesiclepedia_19	16302729	Homo sapiens	Purification, characterization and biological significance of tumor-derived exosomes.	Breast cancer cells	Protein	Differential centrifugation Sucrose density gradient Filtration Immunobeads(HER2)	Exosomes
664	Vesiclepedia_137	22723089	Homo sapiens	Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes.	Prostate cancer cells	Protein	Sucrose density gradient	Exosomes
665	Vesiclepedia_142	22723089	Homo sapiens	Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes.	Prostate cancer cells	Protein	Sucrose density gradient	Exosomes
666	Vesiclepedia_230	2294986	Homo sapiens	Direct detection of activated platelets and platelet-derived microparticles in humans	Plasma	Protein	FACS	Microparticles
667	Vesiclepedia_126	-	Homo sapiens	Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?	Mesenchymal stem cells	Protein	HPLC	Exosomes
668	Vesiclepedia_160	21630462	Homo sapiens	Proteomic analysis of microvesicles derived from human colorectal cancer ascites	Ascites	Protein	Differential centrifugation Sucrose density gradient OptiPrep density gradient	Microvesicles
669	Vesiclepedia_420	21136987	Helicobacter pylori	Proteomic and functional characterization of the outer membrane vesicles from the gastric pathogen Helicobacter pylori.	Helicobacter pylori	Protein	-	Membrane vesicles
670	Vesiclepedia_1056	30035390	Mus musculus	Arrestin-domain Containing Protein 1 (Arrdc1) Regulates the Protein Cargo and Release of Extracellular Vesicles.	Mouse embryonic fibroblasts	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
671	Vesiclepedia_101	21828046	Rattus norvegicus	The proteo-lipidic composition of exosomes changes during reticulocyte maturation.	Reticulocytes	Protein Lipids	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
672	Vesiclepedia_900	26100252	Homo sapiens	Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts	Chronic lymphocytic leukemia cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
673	Vesiclepedia_1165	29904572	Bos taurus	A subset of extracellular vesicles carries the bulk of microRNAs in commercial dairy cow's milk.	Bovine milk	Protein miRNA	Differential centrifugation Density gradient centrifugation	Extracellular vesicles
674	Vesiclepedia_812	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Differential centrifugation Filtration ExoQuick Ultracentrifugation	Exosomes
675	Vesiclepedia_797	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Embryonic kidney cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
676	Vesiclepedia_185	22116803	Equus caballus	Cell-Secreted Vesicles in Equine Ovarian Follicular Fluid Contain miRNAs and Proteins: A Possible New Form of Cell Communication Within the Ovarian Follicle	Follicular fluid	Protein miRNA	Differential centrifugation ExoQuick	Exosomes
677	Vesiclepedia_1224	26154623	Homo sapiens	Size-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals	Plasma	Protein	Exo-spin	Extracellular vesicles
678	Vesiclepedia_2	3597417	Ovis aries	Vesicle formation during reticulocyte maturation. Association of plasma membrane activities with released vesicles (exosomes).	Reticulocytes	Protein Lipids	Differential centrifugation	Exosomes
679	Vesiclepedia_482	23161513	Homo sapiens	Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.	Colorectal cancer cells	Protein	-	Exosomes
680	Vesiclepedia_916	28687758	Sus scrofa	Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers	Polarised retinal pigmented epithelial cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
681	Vesiclepedia_930	29207636	Homo sapiens	Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer.	Bladder cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
682	Vesiclepedia_262	12805058	Homo sapiens	Sickle blood contains tissue factor-positive microparticles derived from endothelial cells and monocytes	Plasma	Protein Lipids	Differential centrifugation Ultracentrifugation FACS	Microparticles
683	Vesiclepedia_216	21293856	Homo sapiens	Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC	Breast cancer cells	Protein	Differential centrifugation Filtration Ultrafiltration Ultracentrifugation Sucrose density gradient	Exosomes
684	Vesiclepedia_1287	20880880	Homo sapiens	Proinflammatory exosomes in bronchoalveolar lavage fluid of patients with sarcoidosis.	Bronchoalveolar lavage fluid	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
685	Vesiclepedia_124	21235781	Homo sapiens	Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages.	Breast milk	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
686	Vesiclepedia_1015	22711894	Homo sapiens	Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages.	Macrophages	Protein Lipids	Differential centrifugation Filtration Ultracentrifugation	Exosomes
687	Vesiclepedia_589	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Colorectal cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
688	Vesiclepedia_96	21828046	Rattus norvegicus	The proteo-lipidic composition of exosomes changes during reticulocyte maturation.	Reticulocytes	Protein Lipids	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
689	Vesiclepedia_997	24392111	Mus musculus	Proteomic analysis of C2C12 myoblast and myotube exosome-like vesicles: a new paradigm for myoblast-myotube cross talk?	Murine myotubues	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
690	Vesiclepedia_15	17486113	Mus musculus Homo sapiens	Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.	Mast cells	Protein mRNA miRNA	Filtration Ultracentrifugation Sucrose density gradient	Exosomes
691	Vesiclepedia_238	21293856	Homo sapiens	Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC	Ascites	Protein	Differential centrifugation Filtration Ultrafiltration Ultracentrifugation Sucrose density gradient	Exosomes
692	Vesiclepedia_817	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Differential centrifugation Filtration ExoQuick Ultracentrifugation	Exosomes
693	Vesiclepedia_1107	24391718	Homo sapiens	Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.	Prostate epithelial cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
694	Vesiclepedia_787	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Embryonic kidney cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
695	Vesiclepedia_712	28811610	Homo sapiens	Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA.	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Apoptotic bodies
696	Vesiclepedia_848	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
697	Vesiclepedia_672	29953960	Homo sapiens	Exosomes derived from calcium oxalate-exposed macrophages enhance IL-8 production from renal cells, neutrophil migration and crystal invasion through extracellular matrix.	Macrophages	Protein	Microfiltration Differential centrifugation Ultracentrifugation	Exosomes
698	Vesiclepedia_140	22723089	Homo sapiens	Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes.	Prostate cancer cells	Protein	Sucrose density gradient	Exosomes
699	Vesiclepedia_254	9126269	Homo sapiens	Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations	Leukemia cells	Protein	Differential centrifugation Sucrose density gradient	Microvesicles
700	Vesiclepedia_263	12805058	Homo sapiens	Sickle blood contains tissue factor-positive microparticles derived from endothelial cells and monocytes	Plasma	Protein	Differential centrifugation Ultracentrifugation FACS	Microparticles
701	Vesiclepedia_1159	20409149	Homo sapiens	Transdifferentiated circulating monocytes release exosomes containing 14-3-3 proteins with matrix metalloproteinase-1 stimulating effect for dermal fibroblasts.	Keratinocytes	Protein	Differential centrifugation Filtration Ultrafiltration Ultracentrifugation Sucrose density gradient	Exosomes
702	Vesiclepedia_883	29955024	Homo sapiens	Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells	Myeloid leukemia cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
703	Vesiclepedia_45	18589210	Homo sapiens	MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer.	Serum	Protein miRNA	Ultracentrifugation Immunobeads (EpCAM)	Exosomes
704	Vesiclepedia_826	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Filtration Ultracentrifugation Sucrose density gradient	Exosomes
705	Vesiclepedia_1118	24391718	Homo sapiens	Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
706	Vesiclepedia_731	25359493	Homo sapiens	Proteomic signatures of extracellular vesicles secreted by nonmineralizing and mineralizing human osteoblasts and stimulation of tumor cell growth.	Osteoblasts	Protein	Differential centrifugation Ultracentrifugation	Matrix vesicles
707	Vesiclepedia_948	28819550	Mus musculus	Effects of storage temperature on airway exosome integrity for diagnostic and functional analyses.	Bronchoalveolar lavage fluid	Protein	Differential centrifugation Ultracentrifugation	Exosomes
708	Vesiclepedia_1188	28326167	Homo sapiens	Residual urinary extracellular vesicles in ultracentrifugation supernatants after hydrostatic filtration dialysis enrichment.	Urine	Protein	Hydrostatic filtration dialysis Differential centrifugation Ultracentrifugation	Extracellular vesicles
709	Vesiclepedia_996	24392111	Mus musculus	Proteomic analysis of C2C12 myoblast and myotube exosome-like vesicles: a new paradigm for myoblast-myotube cross talk?	Murine myoblast	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
710	Vesiclepedia_579	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Breast cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
711	Vesiclepedia_103	21763319	Homo sapiens	Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells.	Pancreatic adenocarcinoma cells	Protein	Differential centrifugation Filtration Ultrafiltration Ultracentrifugation	Exosomes
712	Vesiclepedia_469	23029346	Echinostoma caproni	Extracellular Vesicles from Parasitic Helminths Contain Specific Excretory/Secretory Proteins and Are Internalized in Intestinal Host Cells.	Echinostoma caproni	Protein	-	Exosomes/Extracellular vesicles/Microvesicles
713	Vesiclepedia_767	29953723	Salmo salar	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Leukocytes	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
714	Vesiclepedia_613	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Lung cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
715	Vesiclepedia_556	24069378	Homo sapiens	Proteome profiling of neuroblastoma-derived exosomes reveal the expression of proteins potentially involved in tumor progression.	Neuroblastoma cells	Protein	-	Exosomes/Membrane vesicles
716	Vesiclepedia_29	19109410	Homo sapiens	Proteomic and immunologic analyses of brain tumor exosomes.	Serum	Protein	Differential centrifugation Sucrose density gradient	Exosomes
717	Vesiclepedia_315	15499615	Homo sapiens	Microvesicles derived from activated platelets induce metastasis and angiogenesis in lung cancer	Lung cancer cells	Protein	Differential centrifugation FACS	Microvesicles
718	Vesiclepedia_773	29953723	Salmo salar	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Leukocytes	Protein	Differential centrifugation	Apoptotic bodies
719	Vesiclepedia_270	10903724	Homo sapiens	Follicular dendritic cells carry MHC class II-expressing microvesicles at their surface	Dendritic cells	Protein	-	Microvesicles
720	Vesiclepedia_1228	26154623	Homo sapiens	Size-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals	Plasma	Protein	Size exclusion chromatography	Extracellular vesicles
721	Vesiclepedia_1075	25104112	Homo sapiens	Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy.	Plasma	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Exosomes
722	Vesiclepedia_1167	29907695	Mus musculus	Cancer cells copy migratory behavior and exchange signaling networks via extracellular vesicles.	Melanoma cells	Protein miRNA	Differential centrifugation Ultracentrifugation	Extracellular vesicles
723	Vesiclepedia_1009	23185418	Homo sapiens	Improved flow cytometric assessment reveals distinct microvesicle (cell-derived microparticle) signatures in joint diseases.	Synovial fluid	Protein	Filtration Ultracentrifugation	Microvesicles
724	Vesiclepedia_943	29207636	Homo sapiens	Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer.	Urine	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
725	Vesiclepedia_780	29953723	Salmo salar	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Leukocytes	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
726	Vesiclepedia_1161	22641613	Homo sapiens	Application of systems biology principles to protein biomarker discovery: urinary exosomal proteome in renal transplantation.	Urine	Protein	Differential centrifugation Ultracentrifugation	Exosomes
727	Vesiclepedia_570	26858453	Homo sapiens	Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes	Dendritic cells	Protein	Differential centrifugation Ultracentrifugation Immunobeads (CD63 PD)	Extracellular vesicles
728	Vesiclepedia_77	20224111	Homo sapiens	Proteomics analysis of bladder cancer exosomes.	Urine	Protein	Differential centrifugation Sucrose density gradient	Exosomes
729	Vesiclepedia_292	10415024	Homo sapiens	Activated human T cells release bioactive Fas ligand and APO2 ligand in microvesicles	T cells	Protein	Differential centrifugation Ultracentrifugation FACS	Microvesicles
730	Vesiclepedia_1070	29937354	Homo sapiens	Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors.	Glioblastoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
731	Vesiclepedia_324	20079801	Mus musculus	Microvesicle entry into marrow cells mediates tissue-specific changes in mRNA by direct delivery of mRNA and induction of transcription	Lung cells	Protein miRNA	Differential centrifugation FACS	Microvesicles
732	Vesiclepedia_427	21408115	Edwardsiella tarda	Outer membrane vesicles as a candidate vaccine against edwardsiellosis.	Edwardsiella tarda	Protein	-	Membrane vesicles
733	Vesiclepedia_727	25359493	Homo sapiens	Proteomic signatures of extracellular vesicles secreted by nonmineralizing and mineralizing human osteoblasts and stimulation of tumor cell growth.	Osteoblasts	Protein	Differential centrifugation Ultracentrifugation	Matrix vesicles
734	Vesiclepedia_926	25483805	Homo sapiens	Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties	Embryonic kidney cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
735	Vesiclepedia_939	29207636	Homo sapiens	Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer.	Urine	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
736	Vesiclepedia_576	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Breast cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
737	Vesiclepedia_13	15326289	Homo sapiens	Identification and proteomic profiling of exosomes in human urine.	Urine	Protein	Ultracentrifugation	Exosomes
738	Vesiclepedia_1052	29115712	Mus musculus	Proteomic Profiling of Exosomes Secreted by Breast Cancer Cells with Varying Metastatic Potential.	Breast cancer cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
739	Vesiclepedia_694	28842968	Homo sapiens	Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles.	Colorectal cancer cells	Protein	Differential centrifugation Ultracentrifugation	Microvesicles
740	Vesiclepedia_766	29953723	Salmo salar	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Leukocytes	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
741	Vesiclepedia_1033	29887978	Homo sapiens	Evaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing.	Serum	Protein miRNA	qEV size-exclusion column	Extracellular vesicles
742	Vesiclepedia_622	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Melanoma cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
743	Vesiclepedia_1251	24939845	Homo sapiens	Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein.	Leukemia cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
744	Vesiclepedia_1116	24391718	Homo sapiens	Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.	Prostate epithelial cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
745	Vesiclepedia_918	28687758	Sus scrofa	Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers	Polarised retinal pigmented epithelial cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
746	Vesiclepedia_775	29953723	Salmo salar	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Leukocytes	Protein	Differential centrifugation	Microvesicles
747	Vesiclepedia_818	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Differential centrifugation Filtration ExoQuick Ultracentrifugation	Exosomes
748	Vesiclepedia_1105	24391718	Homo sapiens	Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.	Prostate epithelial cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
749	Vesiclepedia_1160	22641613	Homo sapiens	Application of systems biology principles to protein biomarker discovery: urinary exosomal proteome in renal transplantation.	Urine	Protein	Differential centrifugation Ultracentrifugation	Exosomes
750	Vesiclepedia_1029	26378940	Homo sapiens	Redefining the Breast Cancer Exosome Proteome by Tandem Mass Tag Quantitative Proteomics and Multivariate Cluster Analysis.	Breast cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
751	Vesiclepedia_838	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Differential centrifugation Filtration ExoQuick Ultracentrifugation	Exosomes
752	Vesiclepedia_1171	29881354	Rattus norvegicus	Effects of Acute Aerobic Exercise on Rats Serum Extracellular Vesicles Diameter, Concentration and Small RNAs Content.	Serum	Protein miRNA	ExoQuick	Extracellular vesicles
753	Vesiclepedia_172	21859146	Homo sapiens	Identification of a conserved glycan signature for microvesicles	Melanoma cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Microvesicles
754	Vesiclepedia_626	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Ovarian cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
755	Vesiclepedia_1275	23489476	Sus scrofa	Boar seminal plasma exosomes: effect on sperm function and protein identification by sequencing.	Seminal plasma	Protein	Differential centrifugation Gel filtration Ultracentrifugation	Exosomes
756	Vesiclepedia_284	12796750	Homo sapiens	High levels of circulating endothelial microparticles in patients with acute coronary syndromes	Plasma	Protein	Differential centrifugation FACS	Microparticles
757	Vesiclepedia_388	18570454	Homo sapiens	Proteomic analysis of exosomes from human neural stem cells by flow field-flow fractionation and nanoflow liquid chromatography-tandem mass spectrometry.	Neural stem cells	Protein	-	Exosomes/Membrane vesicles
758	Vesiclepedia_944	29207636	Homo sapiens	Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer.	Urine	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
759	Vesiclepedia_368	16103114	Neisseria meningitidis	Biochemical and functional characterization of membrane blebs purified from Neisseria meningitidis serogroup B.	Neisseria meningitidis	Protein	-	Membrane vesicles
760	Vesiclepedia_244	22148876	Homo sapiens	Proteomic analysis of microvesicles derived from human mesenchymal stem cells	Mesenchymal stem cells	Protein	Differential centrifugation Ultrafiltration Ultracentrifugation Density gradient centrifugation	Microvesicles
761	Vesiclepedia_872	24614226	Ovis aries	Extracellular vesicles in luminal fluid of the ovine uterus	Uterine luminal fluid	Protein	Differential centrifugation Filtration ExoQuick	Extracellular vesicles
762	Vesiclepedia_793	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Embryonic kidney cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
763	Vesiclepedia_734	25359493	Homo sapiens	Proteomic signatures of extracellular vesicles secreted by nonmineralizing and mineralizing human osteoblasts and stimulation of tumor cell growth.	Osteoblasts	Protein	Differential centrifugation Ultracentrifugation	Matrix vesicles
764	Vesiclepedia_931	29207636	Homo sapiens	Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer.	Urothelial cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
765	Vesiclepedia_927	25483805	Homo sapiens	Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties	Embryonic kidney cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
766	Vesiclepedia_121	21276792	Homo sapiens	Morphologic and proteomic characterization of exosomes released by cultured extravillous trophoblast cells.	Trophoblast cells	Protein	Differential centrifugation Ultrafiltration Ultracentrifugation Density gradient centrifugation	Exosomes
767	Vesiclepedia_1260	24371517	Homo sapiens	Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
768	Vesiclepedia_985	25287304	Candida albicans	Compositional and immunobiological analyses of extracellular vesicles released by Candida albicans.	Candida albicans	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
769	Vesiclepedia_397	19413345	Homo sapiens	Proteomic analysis of malignant B-cell derived microparticles reveals CD148 as a potentially useful antigenic biomarker for mantle cell lymphoma diagnosis.	B cells	Protein	-	Microparticles
770	Vesiclepedia_762	29953723	Salmo salar	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Leukocytes	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
771	Vesiclepedia_49	14582906	Homo sapiens	Exosomes with major histocompatibility complex class II and co-stimulatory molecules are present in human BAL fluid.	Bronchoalveolar lavage fluid	Protein	Differential centrifugation Immunobeads (EpCAM)	Exosomes
772	Vesiclepedia_74	19381331	Homo sapiens	High levels of exosomes expressing CD63 and caveolin-1 in plasma of melanoma patients.	Melanoma cells	Protein	Differential centrifugation	Exosomes
773	Vesiclepedia_612	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Lung cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
774	Vesiclepedia_592	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Colorectal cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
775	Vesiclepedia_615	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Lung cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
776	Vesiclepedia_1151	22367951	Acinetobacter baumannii	Acinetobacter baumannii outer membrane protein A modulates the biogenesis of outer membrane vesicles.	Acinetobacter baumannii	Protein	Differential centrifugation Ultrafiltration Ultracentrifugation	Outer membrane vesicles
777	Vesiclepedia_57	17700640	Homo sapiens	CD24 is a marker of exosomes secreted into urine and amniotic fluid.	Urine	Protein	Differential centrifugation Sucrose density gradient	Exosomes
778	Vesiclepedia_611	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Lung cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
779	Vesiclepedia_247	15741221	Homo sapiens	Tissue-factor-bearing microvesicles arise from lipid rafts and fuse with activated platelets to initiate coagulation	Plasma	Protein	Differential centrifugation Immunobeads (TF)	Microvesicles
780	Vesiclepedia_1055	30035390	Mus musculus	Arrestin-domain Containing Protein 1 (Arrdc1) Regulates the Protein Cargo and Release of Extracellular Vesicles.	Mouse embryonic fibroblasts	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
781	Vesiclepedia_508	23511837	Homo sapiens	Differential protein profiling of renal cell carcinoma urinary exosomes.	Urine	Protein	-	Exosomes/Nanovesicles
782	Vesiclepedia_989	25261472	Homo sapiens	Complex N-linked glycans serve as a determinant for exosome/microvesicle cargo recruitment.	Melanoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes/Microvesicles
783	Vesiclepedia_942	29207636	Homo sapiens	Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer.	Urine	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
784	Vesiclepedia_857	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
785	Vesiclepedia_950	27601599	Homo sapiens	Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components.	Breast milk	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
786	Vesiclepedia_176	21788507	Homo sapiens	Hypoxia triggers a proangiogenic pathway involving cancer cell microvesicles and PAR-2-mediated heparin-binding EGF signaling in endothelial cells	Glioblastoma cells	Protein	Differential centrifugation	Microvesicles
787	Vesiclepedia_915	28687758	Sus scrofa	Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers	Polarised retinal pigmented epithelial cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
788	Vesiclepedia_97	21828046	Rattus norvegicus	The proteo-lipidic composition of exosomes changes during reticulocyte maturation.	Reticulocytes	Protein Lipids	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
789	Vesiclepedia_105	21763319	Homo sapiens	Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells.	Pancreatic adenocarcinoma cells	Protein	Differential centrifugation Filtration Ultrafiltration Ultracentrifugation	Exosomes
790	Vesiclepedia_1034	29887978	Homo sapiens	Evaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing.	Serum	Protein miRNA	qEV size-exclusion column	Extracellular vesicles
791	Vesiclepedia_782	29953723	Salmo salar	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Leukocytes	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
792	Vesiclepedia_1190	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
793	Vesiclepedia_888	24946052	Homo sapiens	Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment	Lung cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
794	Vesiclepedia_395	19413345	Homo sapiens	Proteomic analysis of malignant B-cell derived microparticles reveals CD148 as a potentially useful antigenic biomarker for mantle cell lymphoma diagnosis.	B cells	Protein	-	Microparticles
795	Vesiclepedia_1311	-	Saccharomyces cerevisiae	Extracellular vesicles secreted by Saccharomyces cerevisiae are involved in cell wall remodelling	Saccharomyces cerevisiae	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
796	Vesiclepedia_739	25157233	Homo sapiens	Extravillous trophoblast cells-derived exosomes promote vascular smooth muscle cell migration.	Placenta	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
797	Vesiclepedia_759	29953723	Salmo salar	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Leukocytes	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
798	Vesiclepedia_468	23000592	Homo sapiens	In-depth analysis of the secretome identifies three major independent secretory pathways in differentiating human myoblasts.	Neonatal myoblast cells	Protein	-	Microvesicles/Nanovesicles
799	Vesiclepedia_1253	24939845	Homo sapiens	Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein.	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
800	Vesiclepedia_1139	23707955	Bos taurus	Prostasomes from four different species are able to produce extracellular adenosine triphosphate (ATP).	Seminal plasma	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Prostasomes
801	Vesiclepedia_546	23983189	Homo sapiens	Characterization of Multiple Myeloma Vesicles by Label-Free Relative Quantitation.	B cells	Protein	-	Exosomes/Extracellular vesicles/Microvesicles
802	Vesiclepedia_264	18425114	Homo sapiens	Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells	Epidermoid carcinoma cells	Protein	Differential centrifugation Ultracentrifugation	Microvesicles
803	Vesiclepedia_806	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
804	Vesiclepedia_1235	25421927	Heligmosomoides polygyrus	Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity.	Heligmosomoides polygyrus	miRNA Protein	Filtration Ultracentrifugation	Exosomes
805	Vesiclepedia_67	19619303	Homo sapiens	Claudin-containing exosomes in the peripheral circulation of women with ovarian cancer.	Ovarian cancer cells	Protein	Differential centrifugation Sucrose density gradient	Exosomes
806	Vesiclepedia_1131	23954818	Homo sapiens	Qualitative changes in the proteome of extracellular vesicles accompanying cancer cell transition to mesenchymal state.	Squamous carcinoma cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
807	Vesiclepedia_891	24946052	Homo sapiens	Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment	Lung cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
808	Vesiclepedia_354	24115447	Homo sapiens	Comparative proteomics evaluation of plasma exosome isolation techniques and assessment of the stability of exosomes in normal human blood plasma	Plasma	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
809	Vesiclepedia_92	20124479	Rattus norvegicus	Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.	Pancreatic adenocarcinoma cells	Protein mRNA	Differential centrifugation Sucrose density gradient	Exosomes
810	Vesiclepedia_549	24009881	Homo sapiens	Quantitative proteomics of extracellular vesicles derived from human primary and metastatic colorectal cancer cells.	Colorectal cancer cells	Protein	-	Exosomes/Extracellular vesicles/Microvesicles/Ectosomes
811	Vesiclepedia_479	23082778	Homo sapiens	Comparative and Targeted Proteomic Analyses of Urinary Microparticles from Bladder Cancer and Hernia Patients.	Urine	Protein	-	Exosomes/Membrane vesicles
812	Vesiclepedia_478	23082778	Homo sapiens	Comparative and Targeted Proteomic Analyses of Urinary Microparticles from Bladder Cancer and Hernia Patients.	Urine	Protein	-	Exosomes/Membrane vesicles
813	Vesiclepedia_130	18309083	Mus musculus	Ceramide triggers budding of exosome vesicles into multivesicular endosomes	Oligodendrocytes	Protein Lipids	Differential centrifugation Sucrose density gradient	Exosomes
814	Vesiclepedia_217	21293856	Homo sapiens	Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC	Serum	Protein	Differential centrifugation Filtration Ultrafiltration Ultracentrifugation Sucrose density gradient	Exosomes
815	Vesiclepedia_978	22808001	Homo sapiens	Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment.	Serum	Protein	Filtration ExoQuick	Exosomes
816	Vesiclepedia_852	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
817	Vesiclepedia_1208	29127410	Homo sapiens	Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies.	Bronchial epithelial cells	Protein	Ultrafiltration Size exclusion chromatography	Extracellular vesicles
818	Vesiclepedia_912	28687758	Sus scrofa	Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers	Polarised retinal pigmented epithelial cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
819	Vesiclepedia_1231	25503107	Homo sapiens	Tumor-derived microvesicles mediate human breast cancer invasion through differentially glycosylated EMMPRIN.	Breast cancer cells	Protein	Ultracentrifugation Filtration Density gradient centrifugation	Microvesicles
820	Vesiclepedia_488	23230278	Homo sapiens	Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids.	Colorectal cancer cells	Protein	-	Exosomes/Extracellular vesicles/Microvesicles
821	Vesiclepedia_877	29955024	Homo sapiens	Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells	Embryonic kidney cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
822	Vesiclepedia_473	23056467	Homo sapiens	Cause or Effect of Arteriogenesis: Compositional Alterations of Microparticles from CAD Patients Undergoing External Counterpulsation Therapy.	Plasma	Protein	-	Microparticles
823	Vesiclepedia_1300	-	Saccharomyces cerevisiae	Extracellular vesicles secreted by Saccharomyces cerevisiae are involved in cell wall remodelling	Saccharomyces cerevisiae	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
824	Vesiclepedia_220	10694520	Homo sapiens	Elevated levels of shed membrane microparticles with procoagulant potential in the peripheral circulating blood of patients with acute coronary syndromes	Plasma	Protein	Immunoaffinity [Annexin-V]	Microparticles
825	Vesiclepedia_1284	22345510	Rattus norvegicus	Characterization of membrane-shed microvesicles from cytokine-stimulated .-cells using proteomics strategies.	Insulinoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
826	Vesiclepedia_1301	-	Saccharomyces cerevisiae	Extracellular vesicles secreted by Saccharomyces cerevisiae are involved in cell wall remodelling	Saccharomyces cerevisiae	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
827	Vesiclepedia_122	21235781	Homo sapiens	Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages.	Saliva	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
828	Vesiclepedia_650	29188495	Homo sapiens	Protein Biomarkers and Neuroproteomics Characterization of Microvesicles/Exosomes from Human Cerebrospinal Fluid Following Traumatic Brain Injury.	Cerebrospinal fluid	Protein	Differential centrifugation Ultracentrifugation Sonication Filtration	Extracellular vesicles
829	Vesiclepedia_651	29188495	Homo sapiens	Protein Biomarkers and Neuroproteomics Characterization of Microvesicles/Exosomes from Human Cerebrospinal Fluid Following Traumatic Brain Injury.	Cerebrospinal fluid	Protein	Differential centrifugation Ultracentrifugation Sonication Filtration	Extracellular vesicles
830	Vesiclepedia_750	29988836	Homo sapiens	Ultrafiltration and size exclusion chromatography combined with asymmetrical-flow field-flow fractionation for the isolation and characterisation of extracellular vesicles from urine	Urine	Protein	Filtration Size exclusion chromatography	Extracellular vesicles
831	Vesiclepedia_1291	19912576	Homo sapiens	HIV Nef is secreted in exosomes and triggers apoptosis in bystander CD4+ T cells.	Lymphoblasts	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
832	Vesiclepedia_789	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Embryonic kidney cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
833	Vesiclepedia_1110	24391718	Homo sapiens	Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
834	Vesiclepedia_1290	19912576	Homo sapiens	HIV Nef is secreted in exosomes and triggers apoptosis in bystander CD4+ T cells.	Lymphoblasts	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
835	Vesiclepedia_677	29951053	Mus musculus	Immunoregulatory Effects of Myeloid-Derived Suppressor Cell Exosomes in Mouse Model of Autoimmune Alopecia Areata.	Dendritic cells	Protein	Ultracentrifugation Density gradient centrifugation	Exosomes
836	Vesiclepedia_1044	27770278	Homo sapiens	Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease.	Glioblastoma cells	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Extracellular vesicles
837	Vesiclepedia_26	19109410	Mus musculus	Proteomic and immunologic analyses of brain tumor exosomes.	Brain cancer cells	Protein	Differential centrifugation Sucrose density gradient	Exosomes
838	Vesiclepedia_47	17641064	Homo sapiens	Exosomes with immune modulatory features are present in human breast milk.	B cells	Protein	Differential centrifugation Filtration Sucrose density gradient	Exosomes
839	Vesiclepedia_5	11145662	Mus musculus	Mast cell-dependent B and T lymphocyte activation is mediated by the secretion of immunologically active exosomes.	Mast cells	Protein	Differential centrifugation	Exosomes
840	Vesiclepedia_1049	28842968	Homo sapiens	Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles.	Colorectal cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
841	Vesiclepedia_1145	23173708	Rattus norvegicus	Wnt3a induces exosome secretion from primary cultured rat microglia.	Primary microglial cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
842	Vesiclepedia_1058	30035390	Mus musculus	Arrestin-domain Containing Protein 1 (Arrdc1) Regulates the Protein Cargo and Release of Extracellular Vesicles.	Mouse embryonic fibroblasts	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
843	Vesiclepedia_8	12626558	Mus musculus	Mast cell-derived exosomes induce phenotypic and functional maturation of dendritic cells and elicit specific immune responses in vivo.	B cells	Protein	Differential centrifugation	Exosomes
844	Vesiclepedia_59	17700640	Mus musculus	CD24 is a marker of exosomes secreted into urine and amniotic fluid.	Amniotic fluid	Protein	Differential centrifugation Sucrose density gradient	Exosomes
845	Vesiclepedia_1146	23173708	Rattus norvegicus	Wnt3a induces exosome secretion from primary cultured rat microglia.	Primary microglial cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
846	Vesiclepedia_139	22723089	Homo sapiens	Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes.	Prostate cancer cells	Protein	Sucrose density gradient	Exosomes
847	Vesiclepedia_1150	22807456	Homo sapiens	Quantitative proteomic analysis of exosomes from HIV-1-infected lymphocytic cells.	Lymphocytes	Protein	Differential centrifugation Ultracentrifugation	Exosomes
848	Vesiclepedia_1221	27872147	Rattus norvegicus	Primary Human and Rat .-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity.	Insulinoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
849	Vesiclepedia_723	25802036	Homo sapiens	Glioblastoma-derived extracellular vesicles modify the phenotype of monocytic cells.	Glioblastoma cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
850	Vesiclepedia_733	25359493	Homo sapiens	Proteomic signatures of extracellular vesicles secreted by nonmineralizing and mineralizing human osteoblasts and stimulation of tumor cell growth.	Osteoblasts	Protein	Differential centrifugation Ultracentrifugation	Matrix vesicles
851	Vesiclepedia_702	28811610	Homo sapiens	Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA.	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Apoptotic bodies
852	Vesiclepedia_1051	29115712	Mus musculus	Proteomic Profiling of Exosomes Secreted by Breast Cancer Cells with Varying Metastatic Potential.	Breast cancer cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
853	Vesiclepedia_287	12417540	Homo sapiens	Elevated numbers of tissue-factor exposing microparticles correlate with components of the metabolic syndrome in uncomplicated type 2 diabetes mellitus	Plasma	Protein	Differential centrifugation FACS	Microparticles
854	Vesiclepedia_1277	23344851	Rattus norvegicus	Urinary exosomes and diabetic nephropathy: a proteomic approach.	Urine	Protein	Ultracentrifugation	Exosomes
855	Vesiclepedia_409	20031610	Homo sapiens	Proteomics, metabolomics, and immunomics on microparticles derived from human atherosclerotic plaques.	Carotid atherosclerotic plaques	Protein	-	Microparticles
856	Vesiclepedia_125	21059916	Homo sapiens	Human tumor virus utilizes exosomes for intercellular communication.	Nasopharyngeal carcinoma cells	Protein	Differential centrifugation	Exosomes
857	Vesiclepedia_1060	30006486	Homo sapiens	The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells.	Astrocytoma cells	Protein	Filtration Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
858	Vesiclepedia_253	9126269	Homo sapiens	Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations	Leukemia cells	Protein	Differential centrifugation Sucrose density gradient	Microvesicles
859	Vesiclepedia_1019	21734072	Mus musculus	Insulinoma-released exosomes or microparticles are immunostimulatory and can activate autoreactive T cells spontaneously developed in nonobese diabetic mice.	Insulinoma cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
860	Vesiclepedia_1093	25065644	Homo sapiens	Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells.	Duodenal cancer cells	Protein	Differential centrifugation Filtration Ultrafiltration	Exosomes
861	Vesiclepedia_1217	27872147	Rattus norvegicus	Primary Human and Rat .-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity.	Islets	Protein	Differential centrifugation Ultracentrifugation	Exosomes
862	Vesiclepedia_779	29953723	Salmo salar	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Leukocytes	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
863	Vesiclepedia_141	22723089	Homo sapiens	Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes.	Prostate cancer cells	Protein	Sucrose density gradient	Exosomes
864	Vesiclepedia_972	22808001	Homo sapiens	Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment.	Serum	Protein	Filtration ExoQuick	Exosomes
865	Vesiclepedia_856	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
866	Vesiclepedia_681	29148239	Homo sapiens	Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants.	Umblical cord mesenchymal stem cells	Protein	Differential centrifugation Ultracentrifugation Sonication Filtration	Microvesicles
867	Vesiclepedia_1239	25329303	Homo sapiens	Rapid isolation of extracellular vesicles from cell culture and biological fluids using a synthetic peptide with specific affinity for heat shock proteins.	Urine	Protein	Vn96 peptide precipitation	Extracellular vesicles
868	Vesiclepedia_906	29207636	Homo sapiens	Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer	Urothelial cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
869	Vesiclepedia_543	23977379	Listeria monocytogenes	Transcription Factor σ(B) Plays an Important Role in the Production of Extracellular Membrane-Derived Vesicles in Listeria monocytogenes.	Listeria monocytogenes	Protein	-	Membrane vesicles
870	Vesiclepedia_1087	25065644	Homo sapiens	Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells.	Duodenal cancer cells	Protein	Differential centrifugation Filtration Ultrafiltration	Exosomes
871	Vesiclepedia_375	18095356	Gallus gallus	Proteome analysis of matrix vesicles isolated from femurs of chicken embryo.	17-day-old embryo leg bone	Protein	-	Matrix vesicles
872	Vesiclepedia_966	25844599	Homo sapiens	Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.	Serum	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
873	Vesiclepedia_46	17641064	Homo sapiens	Exosomes with immune modulatory features are present in human breast milk.	Breast milk	Protein	Differential centrifugation Filtration Sucrose density gradient	Exosomes
874	Vesiclepedia_507	23511837	Homo sapiens	Differential protein profiling of renal cell carcinoma urinary exosomes.	Urine	Protein	-	Exosomes/Nanovesicles
875	Vesiclepedia_717	26148937	Homo sapiens	Proteomics profiling of cholangiocarcinoma exosomes: A potential role of oncogenic protein transferring in cancer progression.	Cholangiocytes	Protein	Differential centrifugation Ultracentrifugation Filtration	Exosomes
876	Vesiclepedia_882	29955024	Homo sapiens	Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells	Myeloid leukemia cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
877	Vesiclepedia_1084	25104112	Homo sapiens	Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy.	Plasma	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Exosomes
878	Vesiclepedia_744	29988836	Homo sapiens	Ultrafiltration and size exclusion chromatography combined with asymmetrical-flow field-flow fractionation for the isolation and characterisation of extracellular vesicles from urine	Urine	Protein	Filtration Size exclusion chromatography	Extracellular vesicles
879	Vesiclepedia_1090	25065644	Homo sapiens	Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells.	Duodenal cancer cells	Protein	Differential centrifugation Filtration Ultrafiltration	Exosomes
880	Vesiclepedia_1243	25261722	Homo sapiens	Inflammatory cytokines, interleukin-1 beta and tumor necrosis factor-alpha, upregulated in glioblastoma multiforme, raise the levels of CRYAB in exosomes secreted by U373 glioma cells.	Glioblastoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
881	Vesiclepedia_221	9918520	Homo sapiens	Shed membrane microparticles with procoagulant potential in human atherosclerotic plaques: a role for apoptosis in plaque thrombogenicity	Atherosclerotic plaques	Protein Lipids	Differential centrifugation Immunoaffinity [Annexin-V]	Apoptotic bodies
882	Vesiclepedia_862	25776846	Homo sapiens	Human thymic epithelial primary cells produce exosomes carrying tissue-restricted antigens	Epithelial cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
883	Vesiclepedia_16	9685355	Homo sapiens	Selective enrichment of tetraspan proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B-lymphocytes.	B cells	Protein	Differential centrifugation Sucrose density gradient	Exosomes
884	Vesiclepedia_584	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Brain cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
885	Vesiclepedia_1266	24310399	Homo sapiens	Extracellular vesicles modulate the glioblastoma microenvironment via a tumor suppression signaling network directed by miR-1.	Glioblastoma cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Extracellular vesicles
886	Vesiclepedia_298	12796750	Homo sapiens	High levels of circulating endothelial microparticles in patients with acute coronary syndromes	Plasma	Protein	Differential centrifugation FACS	Microparticles
887	Vesiclepedia_163	21901833	Drosophila melanogaster	Proteomics analyses of microvesicles released by Drosophila Kc167 and S2 cells	Hematocytes	Protein	Differential centrifugation Sucrose density gradient Ultracentrifugation	Microvesicles
888	Vesiclepedia_788	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Embryonic kidney cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
889	Vesiclepedia_682	29148239	Homo sapiens	Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants.	Umblical cord mesenchymal stem cells	Protein	Differential centrifugation Ultracentrifugation Sonication Filtration	Microvesicles
890	Vesiclepedia_120	21362503	Homo sapiens	Protein profile of exosomes from trabecular meshwork cells.	Aqueous humor	Protein	Differential centrifugation Sucrose density gradient	Exosomes
891	Vesiclepedia_604	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Leukemia cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
892	Vesiclepedia_234	10648405	Homo sapiens	Cellular origin and procoagulant properties of microparticles in meningococcal sepsis	Plasma	Protein	Differential centrifugation FACS	Microparticles
893	Vesiclepedia_492	23333927	Homo sapiens	Characterization and proteomic analysis of ovarian cancer-derived exosomes.	Ovarian cancer cells	Protein	-	Exosomes
894	Vesiclepedia_965	25844599	Homo sapiens	Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.	Serum	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
895	Vesiclepedia_1153	22057275	Homo sapiens	Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease.	Neuroblastoma cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
896	Vesiclepedia_1014	22711894	Homo sapiens	Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages.	Macrophages	Protein Lipids	Differential centrifugation Filtration Ultracentrifugation	Exosomes
897	Vesiclepedia_749	29988836	Homo sapiens	Ultrafiltration and size exclusion chromatography combined with asymmetrical-flow field-flow fractionation for the isolation and characterisation of extracellular vesicles from urine	Urine	Protein	Filtration Size exclusion chromatography	Extracellular vesicles
898	Vesiclepedia_442	22288420	Paracoccidioides brasiliensis	Vesicle and vesicle-free extracellular proteome of Paracoccidioides brasiliensis: comparative analysis with other pathogenic fungi.	Paracoccidioides brasiliensis	Protein	-	Extracellular vesicles
899	Vesiclepedia_349	22285593	Homo sapiens	Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes.	Colorectal cancer cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
900	Vesiclepedia_347	22285593	Homo sapiens	Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes.	Colorectal cancer cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
901	Vesiclepedia_269	12757771	Homo sapiens	Endothelial cells release phenotypically and quantitatively distinct microparticles in activation and apoptosis	Endothelial cells	Protein	Differential centrifugation FACS	Microparticles
902	Vesiclepedia_614	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Lung cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
903	Vesiclepedia_446	22428779	Klebsiella pneumoniae	Klebsiella pneumoniae secretes outer membrane vesicles that induce the innate immune response.	Klebsiella pneumoniae	Protein	-	Membrane vesicles
904	Vesiclepedia_982	25458527	Homo sapiens	Benchtop isolation and characterization of functional exosomes by sequential filtration	Breast cancer cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
905	Vesiclepedia_227	2942561	Homo sapiens	Platelet surface glycoproteins. Studies on resting and activated platelets and platelet membrane microparticles in normal subjects, and observations in patients during adult respiratory distress syndrome and cardiac surgery	Plasma	Protein	Differential centrifugation	Microparticles
906	Vesiclepedia_400	19548894	Acinetobacter baumannii	Proteome analysis of outer membrane vesicles from a clinical Acinetobacter baumannii isolate.	Acinetobacter baumannii	Protein	-	Membrane vesicles
907	Vesiclepedia_1280	22345510	Rattus norvegicus	Characterization of membrane-shed microvesicles from cytokine-stimulated .-cells using proteomics strategies.	Insulinoma cells	Protein	Differential centrifugation	Microparticles
908	Vesiclepedia_1072	29937354	Homo sapiens	Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors.	Glioblastoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
909	Vesiclepedia_837	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Differential centrifugation Filtration ExoQuick Ultracentrifugation	Exosomes
910	Vesiclepedia_203	19011622	Homo sapiens	Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers	Glioblastoma cells	Protein miRNA mRNA	Differential centrifugation Ultracentrifugation Filtration	Microvesicles
911	Vesiclepedia_1097	24513287	Mus musculus	Lipid synthesis is promoted by hypoxic adipocyte-derived exosomes in 3T3-L1 cells.	adipocytes	Protein	Differential centrifugation Ultracentrifugation Filtration	Exosomes
912	Vesiclepedia_574	27601599	Homo sapiens	Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components	Breast milk	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
913	Vesiclepedia_581	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Brain cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
914	Vesiclepedia_9	12626558	Mus musculus	Mast cell-derived exosomes induce phenotypic and functional maturation of dendritic cells and elicit specific immune responses in vivo.	Macrophages	Protein	Differential centrifugation	Exosomes
915	Vesiclepedia_1207	29127410	Homo sapiens	Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies.	Bronchial epithelial cells	Protein	Ultrafiltration Size exclusion chromatography	Extracellular vesicles
916	Vesiclepedia_377	18346024	Homo sapiens	The proteome of red cell membranes and vesicles during storage in blood bank conditions.	Red blood cells	Protein	-	Microvesicles/Nanovesicles
917	Vesiclepedia_1138	23707955	Homo sapiens	Prostasomes from four different species are able to produce extracellular adenosine triphosphate (ATP).	Seminal plasma	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Prostasomes
918	Vesiclepedia_517	23585443	Homo sapiens	Proteome profiling of exosomes derived from human primary and metastatic colorectal cells reveal differential expression of key metastatic factors and signal transduction components.	Colorectal cancer cells	Protein	-	Exosomes/Membrane vesicles
919	Vesiclepedia_941	29207636	Homo sapiens	Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer.	Urine	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
920	Vesiclepedia_1121	24347249	Homo sapiens	Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation ExoQuick	Exosomes
921	Vesiclepedia_725	25471207	Homo sapiens	Intraluminal proteome and peptidome of human urinary extracellular vesicles.	Urine	Protein	Differential centrifugation Hydrostatic filtration dialysis Ultrafiltration	Exosomes
922	Vesiclepedia_133	19188015	Homo sapiens	Systemic presence and tumor-growth promoting effect of ovarian carcinoma released exosomes	Ovarian cancer cells	Protein Lipids	Differential centrifugation Sucrose density gradient	Exosomes
923	Vesiclepedia_599	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Kidney cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
924	Vesiclepedia_808	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
925	Vesiclepedia_909	29207636	Homo sapiens	Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer	Transitional carcinoma cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
926	Vesiclepedia_1113	24391718	Homo sapiens	Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
927	Vesiclepedia_853	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
928	Vesiclepedia_803	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
929	Vesiclepedia_597	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Kidney cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
930	Vesiclepedia_487	23230278	Homo sapiens	Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids.	Colorectal cancer cells	Protein	-	Exosomes/Extracellular vesicles/Microvesicles
931	Vesiclepedia_565	26858453	Homo sapiens	Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes	Dendritic cells	Protein	Differential centrifugation Ultracentrifugation OptiPrep density gradient	Exosomes
932	Vesiclepedia_1214	29127410	Homo sapiens	Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies.	Bronchial epithelial cells	Protein	Ultracentrifugation	Extracellular vesicles
933	Vesiclepedia_127	21828046	Rattus norvegicus	Proteolipidic Composition of Exosomes Changes during Reticulocyte Maturation	Reticulocytes	Protein Lipids	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
934	Vesiclepedia_846	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
935	Vesiclepedia_954	27601599	Homo sapiens	Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components.	Breast milk	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
936	Vesiclepedia_603	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Leukemia cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
937	Vesiclepedia_1152	22057275	Homo sapiens	Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease.	Neuroblastoma cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
938	Vesiclepedia_738	25157233	Homo sapiens	Extravillous trophoblast cells-derived exosomes promote vascular smooth muscle cell migration.	Placenta choriocarcinoma cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
939	Vesiclepedia_447	22444574	Homo sapiens	Proteomic analysis of microvesicles in human saliva by gel electrophoresis with liquid chromatography-mass spectrometry.	Saliva	Protein	-	Exosomes/Microvesicles
940	Vesiclepedia_63	19056867	Homo sapiens	Large-scale proteomics and phosphoproteomics of urinary exosomes.	Urine	Protein	Differential centrifugation	Exosomes
941	Vesiclepedia_1255	24468161	Homo sapiens	Molecular characterization of exosome-like vesicles from breast cancer cells.	Breast cancer cells	Protein miRNA	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
942	Vesiclepedia_737	25220352	Mus musculus	Surface functionalization of exosomes using click chemistry.	Breast cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
943	Vesiclepedia_1000	24079734	Mus musculus	Immunostimulatory activity of murine keratinocyte-derived exosomes.	Keratinocytes	Protein	Differential centrifugation Ultracentrifugation	Exosomes
944	Vesiclepedia_831	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Differential centrifugation Filtration ExoQuick Ultracentrifugation	Exosomes
945	Vesiclepedia_698	28811610	Homo sapiens	Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA.	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
946	Vesiclepedia_907	29207636	Homo sapiens	Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer	Transitional papilloma cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
947	Vesiclepedia_902	26100252	Homo sapiens	Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts	Chronic lymphocytic leukemia cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
948	Vesiclepedia_595	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Kidney cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
949	Vesiclepedia_634	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Prostate cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
950	Vesiclepedia_305	17478559	Rattus norvegicus	Identification and characterization of microvesicles secreted by 3T3-L1 adipocytes: redox- and hormone-dependent induction of milk fat globule-epidermal growth 8-associated microvesicles	Adipocytes	Protein	Differential centrifugation	Microvesicles
951	Vesiclepedia_868	24614226	Ovis aries	Extracellular vesicles in luminal fluid of the ovine uterus	Uterine luminal fluid	Protein	Differential centrifugation Filtration ExoQuick	Extracellular vesicles
952	Vesiclepedia_53	14975938	Homo sapiens	Proteomic analysis of exosomes isolated from human malignant pleural effusions.	Malignant pleural effusions	Protein	Differential centrifugation Sucrose density gradient	Exosomes
953	Vesiclepedia_924	25483805	Homo sapiens	Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties	Embryonic kidney cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
954	Vesiclepedia_708	28811610	Homo sapiens	Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA.	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Microvesicles
955	Vesiclepedia_1127	24295599	Mus musculus	Exosomes from myeloid-derived suppressor cells carry biologically active proteins.	Myeloid-derived suppressor cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
956	Vesiclepedia_607	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Leukemia cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
957	Vesiclepedia_1089	25065644	Homo sapiens	Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells.	Duodenal cancer cells	Protein	Differential centrifugation Filtration Ultrafiltration	Exosomes
958	Vesiclepedia_887	25102470	Homo sapiens	Examination of the specificity of tumor cell derived exosomes with tumor cells in vitro	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
959	Vesiclepedia_93	20124479	Rattus norvegicus	Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.	Pancreatic adenocarcinoma cells	Protein mRNA	Differential centrifugation Sucrose density gradient	Exosomes
960	Vesiclepedia_936	29207636	Homo sapiens	Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer.	Urine	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
961	Vesiclepedia_461	22848702	Homo sapiens	Medulloblastoma exosome proteomics yield functional roles for extracellular vesicles.	Medulloblastoma cells	Protein	-	Exosomes/Membrane vesicles/Extracellular vesicles
962	Vesiclepedia_807	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
963	Vesiclepedia_523	23658846	Mus musculus	Immunomodulatory impact of leishmania-induced macrophage exosomes: a comparative proteomic and functional analysis.	Macrophages	Protein	-	Exosomes
964	Vesiclepedia_1206	29127410	Homo sapiens	Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies.	Bronchial epithelial cells	Protein	Ultrafiltration Size exclusion chromatography	Extracellular vesicles
965	Vesiclepedia_3	10545503	Mus musculus	Molecular characterization of dendritic cell-derived exosomes. Selective accumulation of the heat shock protein hsc73.	Dendritic cells	Protein	Differential centrifugation Sucrose density gradient	Exosomes
966	Vesiclepedia_621	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Melanoma cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
967	Vesiclepedia_1081	25104112	Homo sapiens	Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy.	Plasma	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Exosomes
968	Vesiclepedia_709	28811610	Homo sapiens	Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA.	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Apoptotic bodies
969	Vesiclepedia_1265	24310399	Homo sapiens	Extracellular vesicles modulate the glioblastoma microenvironment via a tumor suppression signaling network directed by miR-1.	Glioblastoma cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Extracellular vesicles
970	Vesiclepedia_878	29955024	Homo sapiens	Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells	Embryonic kidney cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
971	Vesiclepedia_880	29955024	Homo sapiens	Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells	Myeloid leukemia cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
972	Vesiclepedia_654	28290293	Bos taurus	Comparative proteomic analysis of milk-derived exosomes in human and bovine colostrum and mature milk samples by iTRAQ-coupled LC-MS/MS.	Bovine milk	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Exosomes
973	Vesiclepedia_276	12021310	Homo sapiens	Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles	Melanoma cells	Protein	Differential centrifugation Ultracentrifugation	Microvesicles
974	Vesiclepedia_970	25844599	Homo sapiens	Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.	Serum	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
975	Vesiclepedia_696	28842968	Homo sapiens	Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles.	Colorectal cancer cells	Protein	Differential centrifugation Ultracentrifugation	Microvesicles
976	Vesiclepedia_870	24614226	Ovis aries	Extracellular vesicles in luminal fluid of the ovine uterus	Uterine luminal fluid	Protein	Differential centrifugation Filtration ExoQuick	Extracellular vesicles
977	Vesiclepedia_729	25359493	Homo sapiens	Proteomic signatures of extracellular vesicles secreted by nonmineralizing and mineralizing human osteoblasts and stimulation of tumor cell growth.	Osteoblasts	Protein	Differential centrifugation Ultracentrifugation	Matrix vesicles
978	Vesiclepedia_1080	25104112	Homo sapiens	Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy.	Plasma	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Exosomes
979	Vesiclepedia_1308	-	Saccharomyces cerevisiae	Extracellular vesicles secreted by Saccharomyces cerevisiae are involved in cell wall remodelling	Saccharomyces cerevisiae	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
980	Vesiclepedia_1099	24513287	Mus musculus	Lipid synthesis is promoted by hypoxic adipocyte-derived exosomes in 3T3-L1 cells.	adipocytes	Protein	Differential centrifugation Ultracentrifugation Filtration	Exosomes
981	Vesiclepedia_1246	25167841	Homo sapiens	Antibody-coupled monolithic silica microtips for highthroughput molecular profiling of circulating exosomes.	Serum	Protein	CD9 antibody to Mass Spectrometric Immunoassay monolith pipette tips	Exosomes
982	Vesiclepedia_840	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
983	Vesiclepedia_1241	25329303	Homo sapiens	Rapid isolation of extracellular vesicles from cell culture and biological fluids using a synthetic peptide with specific affinity for heat shock proteins.	Urine	Protein	Vn96 peptide precipitation	Extracellular vesicles
984	Vesiclepedia_484	23214914	Trypanosoma cruzi	Proteomic analysis of Trypanosoma cruzi secretome: characterization of two populations of extracellular vesicles and soluble proteins.	Epimastigotes	Protein	-	Exosomes/Extracellular vesicles/Ectosomes
985	Vesiclepedia_310	22148876	Homo sapiens	Proteomic analysis of microvesicles derived from human mesenchymal stem cells	Mesenchymal stem cells	Protein	Differential centrifugation Ultrafiltration Ultracentrifugation Density gradient centrifugation	Microvesicles
986	Vesiclepedia_303	19930720	Homo sapiens	Colorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells	Colorectal cancer cells	Protein mRNA	Differential centrifugation Ultrafiltration OptiPrep density gradient	Microvesicles
987	Vesiclepedia_586	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Brain cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
988	Vesiclepedia_312	15499615	Homo sapiens	Microvesicles derived from activated platelets induce metastasis and angiogenesis in lung cancer	Lung cancer cells	Protein	Differential centrifugation FACS	Microvesicles
989	Vesiclepedia_255	9126269	Homo sapiens	Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations	Burkitt's lymphoma	Protein	Differential centrifugation Sucrose density gradient	Microvesicles
990	Vesiclepedia_1134	23861904	Homo sapiens	Exosomal signaling during hypoxia mediates microvascular endothelial cell migration and vasculogenesis.	Placental mesenchymal stem cells	Protein	Differential centrifugation Ultracentrifugation Ultrafiltration Density gradient centrifugation	Exosomes
991	Vesiclepedia_1043	27770278	Homo sapiens	Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease.	Glioblastoma cells	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Extracellular vesicles
992	Vesiclepedia_559	26098775	Citrus Limon L.	Citrus limon-derived nanovesicles inhibit cancer cell proliferation and suppress CML xenograft growth by inducing TRAIL-mediated cell death	Lemon juice	Protein	Differential centrifugation Ultracentrifugation	Microvesicles
993	Vesiclepedia_241	16192427	Homo sapiens	Circulating endothelial microparticles are associated with vascular dysfunction in patients with end-stage renal failure	Plasma	Protein	Differential centrifugation FACS	Microparticles
994	Vesiclepedia_587	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Colorectal cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
995	Vesiclepedia_222	12514112	Homo sapiens	Intravascular tissue factor initiates coagulation via circulating microvesicles and platelets	Plasma	Protein	Differential centrifugation FACS	Microvesicles
996	Vesiclepedia_1187	28326167	Homo sapiens	Residual urinary extracellular vesicles in ultracentrifugation supernatants after hydrostatic filtration dialysis enrichment.	Urine	Protein	Hydrostatic filtration dialysis Differential centrifugation Ultracentrifugation	Extracellular vesicles
997	Vesiclepedia_973	22808001	Homo sapiens	Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment.	Serum	Protein	Filtration ExoQuick	Exosomes
998	Vesiclepedia_754	29963269	Homo sapiens	Mining of potential microRNAs with clinical correlation - regulation of syndecan-1 expression by miR-122-5p altered mobility of breast cancer cells and possible correlation with liver injury	Hepatoma cells	Protein	Total Exosome Isolation Kit Differential centrifugation	Exosomes
999	Vesiclepedia_881	29955024	Homo sapiens	Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells	Myeloid leukemia cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
1000	Vesiclepedia_437	22106071	Homo sapiens	Proteomic analysis of urine exosomes by multidimensional protein identification technology (MudPIT).	Urine	Protein	-	Exosomes/Membrane vesicles
1001	Vesiclepedia_914	28687758	Sus scrofa	Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers	Polarised retinal pigmented epithelial cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
1002	Vesiclepedia_623	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Melanoma cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
1003	Vesiclepedia_14	16081791	Mus musculus	Proteomic analysis of microglia-derived exosomes: metabolic role of the aminopeptidase CD13 in neuropeptide catabolism.	Microglia	Protein	Differential centrifugation Sucrose density gradient	Exosomes
1004	Vesiclepedia_1172	29881354	Rattus norvegicus	Effects of Acute Aerobic Exercise on Rats Serum Extracellular Vesicles Diameter, Concentration and Small RNAs Content.	Serum	Protein miRNA	ExoQuick	Extracellular vesicles
1005	Vesiclepedia_98	21828046	Rattus norvegicus	The proteo-lipidic composition of exosomes changes during reticulocyte maturation.	Reticulocytes	Protein Lipids	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
1006	Vesiclepedia_551	24009886	Homo sapiens	Cellular stress conditions are reflected in the protein and RNA content of endothelial cell-derived exosomes.	Endothelial cells	Protein	-	Exosomes/Extracellular vesicles
1007	Vesiclepedia_106	21763319	Homo sapiens	Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells.	Pancreatic adenocarcinoma cells	Protein	Differential centrifugation Filtration Ultrafiltration Ultracentrifugation	Exosomes
1008	Vesiclepedia_735	25285581	Mus musculus	Ubiquitinated proteins in exosomes secreted by myeloid-derived suppressor cells.	Myeloid-derived suppressor cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
1009	Vesiclepedia_537	23818640	Homo sapiens	Modulation of B-cell exosome proteins by gamma herpesvirus infection.	B cells	Protein	-	Exosomes/Microvesicles/Oncosomes/Microparticles
1010	Vesiclepedia_606	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Leukemia cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
1011	Vesiclepedia_816	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Differential centrifugation Filtration ExoQuick Ultracentrifugation	Exosomes
1012	Vesiclepedia_770	29953723	Salmo salar	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Leukocytes	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
1013	Vesiclepedia_1189	28326167	Homo sapiens	Residual urinary extracellular vesicles in ultracentrifugation supernatants after hydrostatic filtration dialysis enrichment.	Urine	Protein	Hydrostatic filtration dialysis Differential centrifugation Ultracentrifugation	Extracellular vesicles
1014	Vesiclepedia_908	29207636	Homo sapiens	Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer	Transitional carcinoma cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
1015	Vesiclepedia_311	22148876	Homo sapiens	Proteomic analysis of microvesicles derived from human mesenchymal stem cells	Mesenchymal stem cells	Protein	Differential centrifugation Ultrafiltration Ultracentrifugation Density gradient centrifugation	Microvesicles
1016	Vesiclepedia_1232	25475747	Homo sapiens	Identification of Biomarkers for PKD1 Using Urinary Exosomes	Urine	Protein	Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
1017	Vesiclepedia_286	12417540	Homo sapiens	Elevated numbers of tissue-factor exposing microparticles correlate with components of the metabolic syndrome in uncomplicated type 2 diabetes mellitus	Plasma	Protein	Differential centrifugation FACS	Microparticles
1018	Vesiclepedia_706	28811610	Homo sapiens	Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA.	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Microvesicles/Apoptotic bodies
1019	Vesiclepedia_237	21293856	Homo sapiens	Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC	Melanoma cells	Protein	Differential centrifugation Filtration Ultrafiltration Ultracentrifugation Sucrose density gradient	Exosomes
1020	Vesiclepedia_90	21828046	Rattus norvegicus	The proteo-lipidic composition of exosomes changes during reticulocyte maturation.	Reticulocytes	Protein Lipids	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
1021	Vesiclepedia_841	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
1022	Vesiclepedia_162	21901833	Drosophila melanogaster	Proteomics analyses of microvesicles released by Drosophila Kc167 and S2 cells	Hematocytes	Protein PTM Ubiquitination	Differential centrifugation Sucrose density gradient Ultracentrifugation	Microvesicles
1023	Vesiclepedia_192	21635979	Mus musculus	Proteomic characterization of thymocyte-derived microvesicles and apoptotic bodies in BALB/c mice	Thymus	Protein	Differential centrifugation Filtration	Apoptotic bodies
1024	Vesiclepedia_243	22149170	Homo sapiens	The Protein Interaction Network of Extracellular Vesicles Derived from Human Colorectal Cancer Cells	Colorectal cancer cells	Protein	Differential centrifugation Ultrafiltration Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
1025	Vesiclepedia_582	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Brain cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
1026	Vesiclepedia_445	22418980	Homo sapiens	A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.	Urine	Protein	-	Exosomes
1027	Vesiclepedia_1086	25065644	Homo sapiens	Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells.	Duodenal cancer cells	Protein	Differential centrifugation Filtration Ultrafiltration	Exosomes
1028	Vesiclepedia_378	18346024	Homo sapiens	The proteome of red cell membranes and vesicles during storage in blood bank conditions.	Red blood cells	Protein	-	Microvesicles/Nanovesicles
1029	Vesiclepedia_1286	20880880	Homo sapiens	Proinflammatory exosomes in bronchoalveolar lavage fluid of patients with sarcoidosis.	Bronchoalveolar lavage fluid	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
1030	Vesiclepedia_331	19627513	Homo sapiens	Exosomes from human saliva as a source of microRNA biomarkers	Saliva	Protein miRNA	Differential centrifugation Ultracentrifugation	Exosomes
1031	Vesiclepedia_716	26317203	Homo sapiens	Progression of Osteosarcoma from a Non-Metastatic to a Metastatic Phenotype Is Causally Associated with Activation of an Autocrine and Paracrine uPA Axis.	Osteosarcoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
1032	Vesiclepedia_938	29207636	Homo sapiens	Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer.	Urine	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
1033	Vesiclepedia_145	22723089	Homo sapiens	Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes.	Prostate cancer cells	Protein	Sucrose density gradient	Exosomes
1034	Vesiclepedia_55	12147373	Homo sapiens	Malignant effusions and immunogenic tumour-derived exosomes.	Malignant pleural effusions	Protein	Differential centrifugation Sucrose density gradient	Exosomes
1035	Vesiclepedia_652	28290293	Homo sapiens	Comparative proteomic analysis of milk-derived exosomes in human and bovine colostrum and mature milk samples by iTRAQ-coupled LC-MS/MS.	Breast milk	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Exosomes
1036	Vesiclepedia_799	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Embryonic kidney cells	Protein	Differential centrifugation	Microvesicles
1037	Vesiclepedia_975	22808001	Homo sapiens	Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment.	Serum	Protein	Filtration ExoQuick	Exosomes
1038	Vesiclepedia_316	18472965	Homo sapiens	Cathepsin B mediates the pH-dependent proinvasive activity of tumor-shed microvesicles	Ovarian cancer cells	Protein	Differential centrifugation	Microvesicles
1039	Vesiclepedia_1037	29887978	Homo sapiens	Evaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing.	Serum	Protein miRNA	miRCURY Exosome Isolation Kit	Extracellular vesicles
1040	Vesiclepedia_602	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Leukemia cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
1041	Vesiclepedia_736	25285581	Mus musculus	Ubiquitinated proteins in exosomes secreted by myeloid-derived suppressor cells.	Myeloid-derived suppressor cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
1042	Vesiclepedia_195	21668449	Mus musculus	SV31 is a Zn2+-binding synaptic vesicle protein	Pheochromocytoma cells	Protein	Differential centrifugation Sucrose density gradient	Large dense core vesicles
1043	Vesiclepedia_785	29953723	Salmo salar	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Epithelial cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
1044	Vesiclepedia_1020	21734072	Mus musculus	Insulinoma-released exosomes or microparticles are immunostimulatory and can activate autoreactive T cells spontaneously developed in nonobese diabetic mice.	Insulinoma cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
1045	Vesiclepedia_1276	23344851	Rattus norvegicus	Urinary exosomes and diabetic nephropathy: a proteomic approach.	Urine	Protein	Ultracentrifugation	Exosomes
1046	Vesiclepedia_684	29148239	Homo sapiens	Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants.	Umblical cord mesenchymal stem cells	Protein	Differential centrifugation Ultracentrifugation Sonication Filtration	Microvesicles
1047	Vesiclepedia_432	21751344	Pseudomonas aeruginosa	Proteomic analysis of outer membrane vesicles derived from Pseudomonas aeruginosa.	Pseudomonas aeruginosa	Protein	-	Exosomes/Membrane vesicles
1048	Vesiclepedia_1007	23463506	Mus musculus	The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes.	T cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
1049	Vesiclepedia_1048	28725021	Bos taurus	Bovine milk-derived exosomes from colostrum are enriched with proteins implicated in immune response and growth.	Bovine milk	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
1050	Vesiclepedia_828	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Filtration Ultracentrifugation Sucrose density gradient	Exosomes
1051	Vesiclepedia_1123	24347249	Homo sapiens	Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation ExoQuick	Exosomes
1052	Vesiclepedia_610	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Lung cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
1053	Vesiclepedia_501	23410224	Neisseria meningitidis	Quantitative proteomics reveals distinct differences in the protein content of outer membrane vesicle vaccines.	Neisseria meningitidis	Protein	-	Membrane vesicles
1054	Vesiclepedia_1222	26272980	Homo sapiens	Proteomic Profiling of Detergent Resistant Membranes (Lipid Rafts) of Prostasomes	Seminal plasma	Protein	Ultracentrifugation Density gradient centrifugation	Prostasomes
1055	Vesiclepedia_521	23645497	Canis lupus familiaris	Oncogenic H-Ras reprograms Madin-Darby canine kidney (MDCK) cell-derived exosomal proteins following epithelial-mesenchymal transition.	Kidney cells	Protein	-	Exosomes/Extracellular vesicles
1056	Vesiclepedia_679	29951053	Mus musculus	Immunoregulatory Effects of Myeloid-Derived Suppressor Cell Exosomes in Mouse Model of Autoimmune Alopecia Areata.	Myeloid-derived suppressor cells	Protein	Ultracentrifugation Density gradient centrifugation	Exosomes
1057	Vesiclepedia_201	21606166	Homo sapiens	Blast-derived microvesicles in sera from patients with acute myeloid leukemia suppress natural killer cell function via membrane-associated transforming growth factor-beta2	Serum	Protein	Size exclusion chromatography Ultracentrifugation	Microvesicles
1058	Vesiclepedia_385	18563738	Homo sapiens	Comparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles.	Endothelial cells	Protein	-	Microparticles
1059	Vesiclepedia_894	24946052	Homo sapiens	Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment	Lung cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
1060	Vesiclepedia_1285	21871517	Burkholderia pseudomallei	A naturally derived outer-membrane vesicle vaccine protects against lethal pulmonary Burkholderia pseudomallei infection.	Burkholderia pseudomallei	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Outer membrane vesicles
1061	Vesiclepedia_1279	22345510	Rattus norvegicus	Characterization of membrane-shed microvesicles from cytokine-stimulated .-cells using proteomics strategies.	Insulinoma cells	Protein	Differential centrifugation	Microparticles
1062	Vesiclepedia_683	29148239	Homo sapiens	Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants.	Umblical cord mesenchymal stem cells	Protein	Differential centrifugation Ultracentrifugation Sonication Filtration	Microvesicles
1063	Vesiclepedia_609	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Lung cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
1064	Vesiclepedia_280	15499615	Homo sapiens	Microvesicles derived from activated platelets induce metastasis and angiogenesis in lung cancer	Lung cancer cells	Protein mRNA	Differential centrifugation FACS	Microvesicles
1065	Vesiclepedia_1088	25065644	Homo sapiens	Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells.	Duodenal cancer cells	Protein	Differential centrifugation Filtration Ultrafiltration	Exosomes
1066	Vesiclepedia_920	28687758	Sus scrofa	Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers	Polarised retinal pigmented epithelial cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
1067	Vesiclepedia_348	22285593	Homo sapiens	Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes.	Colorectal cancer cells	Protein	Differential centrifugation Filtration Immunoaffinity (EpCAM) Ultracentrifugation	Exosomes
1068	Vesiclepedia_246	18425114	Homo sapiens	Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells	Glioblastoma cells	Protein	Differential centrifugation Ultracentrifugation	Microvesicles
1069	Vesiclepedia_1227	26154623	Homo sapiens	Size-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals	Plasma	Protein	Size exclusion chromatography	Extracellular vesicles
1070	Vesiclepedia_1173	29881354	Rattus norvegicus	Effects of Acute Aerobic Exercise on Rats Serum Extracellular Vesicles Diameter, Concentration and Small RNAs Content.	Serum	Protein miRNA	ExoQuick	Extracellular vesicles
1071	Vesiclepedia_1059	30006486	Homo sapiens	The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells.	Astrocytoma cells	Protein	Filtration Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
1072	Vesiclepedia_1065	29963299	Homo sapiens	Enrichment of extracellular vesicles from human synovial fluid using size exclusion chromatography.	Synovial fluid	Protein	Size exclusion chromatography	Extracellular vesicles
1073	Vesiclepedia_822	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Filtration Ultracentrifugation Sucrose density gradient	Exosomes
1074	Vesiclepedia_434	22014850	Rattus norvegicus	Proteomics of microparticles after experimental pulmonary embolism.	Plasma	Protein	-	Microparticles
1075	Vesiclepedia_730	25359493	Homo sapiens	Proteomic signatures of extracellular vesicles secreted by nonmineralizing and mineralizing human osteoblasts and stimulation of tumor cell growth.	Osteoblasts	Protein	Differential centrifugation Ultracentrifugation	Matrix vesicles
1076	Vesiclepedia_1141	23454749	Homo sapiens	BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression.	Bone marrow mesenchymal stromal cells	Protein	Differential centrifugation Ultracentrifugation Filtration ExoQuick	Exosomes
1077	Vesiclepedia_713	28811610	Homo sapiens	Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA.	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
1078	Vesiclepedia_1233	25469510	Homo sapiens	GAIP interacting protein C-terminus regulates autophagy and exosome biogenesis of pancreatic cancer through metabolic pathways.	Pancreatic cancer cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
1079	Vesiclepedia_398	19530224	Homo sapiens	Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes.	Keratinocytes	Protein	-	Exosomes
1080	Vesiclepedia_1135	23861904	Homo sapiens	Exosomal signaling during hypoxia mediates microvascular endothelial cell migration and vasculogenesis.	Placental mesenchymal stem cells	Protein	Differential centrifugation Ultracentrifugation Ultrafiltration Density gradient centrifugation	Exosomes
1081	Vesiclepedia_493	23333927	Homo sapiens	Characterization and proteomic analysis of ovarian cancer-derived exosomes.	Ovarian cancer cells	Protein	-	Exosomes
1082	Vesiclepedia_721	26148937	Homo sapiens	Proteomics profiling of cholangiocarcinoma exosomes: A potential role of oncogenic protein transferring in cancer progression.	Cholangiocarcinoma cells	Protein	Differential centrifugation Ultracentrifugation Filtration	Exosomes
1083	Vesiclepedia_23	11231627	Mus musculus	Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming.	Breast cancer cells	Protein	Differential centrifugation Sucrose density gradient	Exosomes
1084	Vesiclepedia_988	25261472	Homo sapiens	Complex N-linked glycans serve as a determinant for exosome/microvesicle cargo recruitment.	Melanoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes/Microvesicles
1085	Vesiclepedia_1169	29907695	Mus musculus	Cancer cells copy migratory behavior and exchange signaling networks via extracellular vesicles.	Melanoma cells	Protein miRNA	Differential centrifugation Ultracentrifugation	Extracellular vesicles
1086	Vesiclepedia_214	21364924	Homo sapiens	Thermal- and oxidative stress causes enhanced release of NKG2D ligand-bearing immunosuppressive exosomes in leukemia/lymphoma T and B cells	T cells	Protein	Differential centrifugation Ultracentrifugation Filtration Sucrose density gradient FACS	Exosomes
1087	Vesiclepedia_383	18373357	Homo sapiens	Isolation and identification of potential urinary microparticle biomarkers of bladder cancer.	Urine	Protein	-	Microparticles
1088	Vesiclepedia_413	20535238	Rattus norvegicus	Candidate biomarkers in exosome-like vesicles purified from rat and mouse urine samples.	Urine	Protein	-	Exosomes
1089	Vesiclepedia_885	29955024	Homo sapiens	Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells	Myeloid leukemia cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
1090	Vesiclepedia_905	29207636	Homo sapiens	Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer	Bladder cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
1091	Vesiclepedia_1054	29115712	Mus musculus	Proteomic Profiling of Exosomes Secreted by Breast Cancer Cells with Varying Metastatic Potential.	Breast cancer cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
1092	Vesiclepedia_159	21630462	Homo sapiens	Proteomic analysis of microvesicles derived from human colorectal cancer ascites	Ascites	Protein	Differential centrifugation Sucrose density gradient OptiPrep density gradient	Microvesicles
1093	Vesiclepedia_271	10903724	Homo sapiens	Follicular dendritic cells carry MHC class II-expressing microvesicles at their surface	B cells	Protein	Differential centrifugation	Exosomes
1094	Vesiclepedia_372	17096383	Mus musculus	Analysis of the extracellular matrix vesicle proteome in mineralizing osteoblasts.	Osteoblasts	Protein	-	Matrix vesicles
1095	Vesiclepedia_386	18563738	Homo sapiens	Comparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles.	Endothelial cells	Protein	-	Microparticles
1096	Vesiclepedia_297	12796750	Homo sapiens	High levels of circulating endothelial microparticles in patients with acute coronary syndromes	Plasma	Protein	Differential centrifugation FACS	Microparticles
1097	Vesiclepedia_110	21601258	Homo sapiens	Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage.	Ascites	Protein miRNA	Differential centrifugation Sucrose density gradient	Exosomes
1098	Vesiclepedia_1028	26378940	Homo sapiens	Redefining the Breast Cancer Exosome Proteome by Tandem Mass Tag Quantitative Proteomics and Multivariate Cluster Analysis.	Breast cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
1099	Vesiclepedia_225	10393703	Homo sapiens	In vitro generation of endothelial microparticles and possible prothrombotic activity in patients with lupus anticoagulant	Plasma	Protein	Differential centrifugation	Microparticles
1100	Vesiclepedia_769	29953723	Salmo salar	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Leukocytes	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
1101	Vesiclepedia_1273	24058411	Homo sapiens	Osteoprotegerin in exosome-like vesicles from human cultured tubular cells and urine.	Urine	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
1102	Vesiclepedia_625	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Melanoma cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
1103	Vesiclepedia_186	22116803	Equus caballus	Cell-Secreted Vesicles in Equine Ovarian Follicular Fluid Contain miRNAs and Proteins: A Possible New Form of Cell Communication Within the Ovarian Follicle	Follicular fluid	Protein miRNA	Differential centrifugation Ultracentrifugation	Microvesicles
1104	Vesiclepedia_428	21515422	Homo sapiens	Proteomic characterization of biogenesis and functions of matrix vesicles released from mineralizing human osteoblast-like cells.	Osteosarcoma cells	Protein	-	Matrix vesicles
1105	Vesiclepedia_1117	24391718	Homo sapiens	Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.	Prostate epithelial cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
1106	Vesiclepedia_1046	28725021	Bos taurus	Bovine milk-derived exosomes from colostrum are enriched with proteins implicated in immune response and growth.	Bovine milk	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
1107	Vesiclepedia_678	29951053	Mus musculus	Immunoregulatory Effects of Myeloid-Derived Suppressor Cell Exosomes in Mouse Model of Autoimmune Alopecia Areata.	Myeloid-derived suppressor cells	Protein	Ultracentrifugation Density gradient centrifugation	Exosomes
1108	Vesiclepedia_367	12746840	Homo sapiens	Proteomic analysis of human prostasomes.	Seminal fluid	Protein	-	Prostasomes
1109	Vesiclepedia_390	19158352	Homo sapiens	Characterization of PKD protein-positive exosome-like vesicles.	Urine	Protein	-	Exosomes/Membrane particles
1110	Vesiclepedia_833	23376832	Rattus norvegicus	Cardiac myocyte exosomes: stability, HSP60, and proteomics	Cardiomyocytes	Protein	Differential centrifugation Filtration ExoQuick Ultracentrifugation	Exosomes
1111	Vesiclepedia_593	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Colorectal cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
1112	Vesiclepedia_1281	22345510	Rattus norvegicus	Characterization of membrane-shed microvesicles from cytokine-stimulated .-cells using proteomics strategies.	Insulinoma cells	Protein	Differential centrifugation	Microparticles
1113	Vesiclepedia_294	2071604	Homo sapiens	Evidence that agonist-induced activation of calpain causes the shedding of procoagulant-containing microvesicles from the membrane of aggregating platelets	Platelets	Protein	Differential centrifugation Filtration	Microvesicles
1114	Vesiclepedia_1312	-	Saccharomyces cerevisiae	Extracellular vesicles secreted by Saccharomyces cerevisiae are involved in cell wall remodelling	Saccharomyces cerevisiae	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
1115	Vesiclepedia_675	29951053	Mus musculus	Immunoregulatory Effects of Myeloid-Derived Suppressor Cell Exosomes in Mouse Model of Autoimmune Alopecia Areata.	Myeloid-derived suppressor cells	Protein	Ultracentrifugation Density gradient centrifugation	Exosomes
1116	Vesiclepedia_1057	30035390	Mus musculus	Arrestin-domain Containing Protein 1 (Arrdc1) Regulates the Protein Cargo and Release of Extracellular Vesicles.	Mouse embryonic fibroblasts	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
1117	Vesiclepedia_252	9126269	Homo sapiens	Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations	T cells	Protein	Differential centrifugation Sucrose density gradient	Microvesicles
1118	Vesiclepedia_685	29148239	Homo sapiens	Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants.	Umblical cord mesenchymal stem cells	Protein	Differential centrifugation Ultracentrifugation Sonication Filtration	Microvesicles
1119	Vesiclepedia_564	26858453	Homo sapiens	Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes	Dendritic cells	Protein	Differential centrifugation Ultracentrifugation OptiPrep density gradient	Exosomes
1120	Vesiclepedia_449	22448133	Pseudomonas aeruginosa	Vesiculation from Pseudomonas aeruginosa under SOS.	Pseudomonas aeruginosa	Protein	-	Membrane vesicles
1121	Vesiclepedia_686	29148239	Homo sapiens	Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants.	Umblical cord mesenchymal stem cells	Protein	Differential centrifugation Ultracentrifugation Sonication Filtration	Microvesicles