Browse results for organism: Homo sapiens

	Vesiclepedia ID	PubMed ID	Species	Experiment description	Sample	Identifications	Isolation methods	Vesicle type
1	Vesiclepedia_1261	24371517	Homo sapiens	Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
2	Vesiclepedia_321	19951903	Homo sapiens	MicroRNA-29a regulates intestinal membrane permeability in patients with irritable bowel syndrome	Plasma	miRNA	Differential centrifugation Filtration	Microvesicles
3	Vesiclepedia_608	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Lung cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
4	Vesiclepedia_171	21859146	Homo sapiens	Identification of a conserved glycan signature for microvesicles	Colorectal cancer cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Microvesicles
5	Vesiclepedia_48	17641064	Homo sapiens	Exosomes with immune modulatory features are present in human breast milk.	Breast milk	Protein	Differential centrifugation Filtration Sucrose density gradient	Exosomes
6	Vesiclepedia_933	29207636	Homo sapiens	Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer.	Bladder cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
7	Vesiclepedia_1210	29127410	Homo sapiens	Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies.	Bronchial epithelial cells	Protein	Ultrafiltration Size exclusion chromatography	Extracellular vesicles
8	Vesiclepedia_1111	24391718	Homo sapiens	Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
9	Vesiclepedia_462	22849433	Homo sapiens	Selective extracellular vesicle-mediated export of an overlapping set of microRNAs from multiple cell types.	Embryonic kidney cells	miRNA	-	Extracellular vesicles
10	Vesiclepedia_1265	24310399	Homo sapiens	Extracellular vesicles modulate the glioblastoma microenvironment via a tumor suppression signaling network directed by miR-1.	Glioblastoma cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Extracellular vesicles
11	Vesiclepedia_1021	20332430	Homo sapiens	Proteomic analysis of prostate cancer metastasis-derived prostasomes.	Skeletal tissue	Protein	Differential centrifugation Ultracentrifugation	Prostasomes
12	Vesiclepedia_20	17956143	Homo sapiens	Proteomic analysis of microvesicles derived from human colorectal cancer cells.	Colorectal cancer cells	Protein	Differential centrifugation Sucrose density gradient Diafiltration	Exosomes
13	Vesiclepedia_1005	23463506	Homo sapiens	The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes.	T cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
14	Vesiclepedia_301	19234131	Homo sapiens	Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR	Endothelial cells	Protein	Differential centrifugation	Microvesicles
15	Vesiclepedia_211	21368175	Homo sapiens	Cancer cell-derived microvesicles induce transformation by transferring tissue transglutaminase and fibronectin to recipient cells	Glioma cells	Protein	Differential centrifugation Filtration	Microvesicles
16	Vesiclepedia_946	29207636	Homo sapiens	Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer.	Urine	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
17	Vesiclepedia_40	15908444	Homo sapiens	Exosomal-like vesicles are present in human blood plasma.	Plasma	Protein	Differential centrifugation Filtration Sucrose density gradient	Exosomes
18	Vesiclepedia_516	23539611	Homo sapiens	microRNA signature is altered in both human epididymis and seminal microvesicles following vasectomy.	Seminal fluid	miRNA	-	Microvesicles
19	Vesiclepedia_633	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Prostate cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
20	Vesiclepedia_714	28811610	Homo sapiens	Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA.	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Microvesicles
21	Vesiclepedia_1188	28326167	Homo sapiens	Residual urinary extracellular vesicles in ultracentrifugation supernatants after hydrostatic filtration dialysis enrichment.	Urine	Protein	Hydrostatic filtration dialysis Differential centrifugation Ultracentrifugation	Extracellular vesicles
22	Vesiclepedia_790	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Embryonic kidney cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
23	Vesiclepedia_1026	22327366	Homo sapiens	Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs.	Vascular endothelial cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
24	Vesiclepedia_703	28811610	Homo sapiens	Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA.	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Apoptotic bodies
25	Vesiclepedia_403	19548909	Homo sapiens	Differential stimulation of monocytic cells results in distinct populations of microparticles.	Monocytes	Protein	-	Microparticles
26	Vesiclepedia_404	19548909	Homo sapiens	Differential stimulation of monocytic cells results in distinct populations of microparticles.	Monocytes	Protein	-	Microparticles
27	Vesiclepedia_968	25844599	Homo sapiens	Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.	Serum	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
28	Vesiclepedia_665	29956871	Homo sapiens	Expression analysis of extracellular microRNA in bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis	Bronchoalveolar lavage fluid	miRNA	Differential centrifugation Ultracentrifugation Filtration	Exosomes
29	Vesiclepedia_245	9126269	Homo sapiens	Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations	T cells	Protein mRNA	Differential centrifugation Sucrose density gradient	Microvesicles
30	Vesiclepedia_183	21741384	Homo sapiens	A filtration-based protocol to isolate human plasma membrane-derived vesicles and exosomes from blood plasma	Plasma	Protein	Differential centrifugation Filtration	Microvesicles
31	Vesiclepedia_903	25053844	Homo sapiens	Activity-associated miRNA are packaged in Map1b-enriched exosomes released from depolarized neurons	Neuroblastoma cells	Protein	Differential centrifugation Ultracentrifugation Filtration	Exosomes
32	Vesiclepedia_1274	23807490	Homo sapiens	Glioma microvesicles carry selectively packaged coding and non-coding RNAs which alter gene expression in recipient cells.	Glioblastoma cells	Protein miRNA	Differential centrifugation	Microvesicles
33	Vesiclepedia_313	15499615	Homo sapiens	Microvesicles derived from activated platelets induce metastasis and angiogenesis in lung cancer	Lung cancer cells	Protein	Differential centrifugation FACS	Microvesicles
34	Vesiclepedia_1013	22711894	Homo sapiens	Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages.	Macrophages	Protein Lipids	Differential centrifugation Filtration Ultracentrifugation	Exosomes
35	Vesiclepedia_663	29956871	Homo sapiens	Expression analysis of extracellular microRNA in bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis	Bronchoalveolar lavage fluid	Protein	Differential centrifugation Ultracentrifugation Filtration	Exosomes
36	Vesiclepedia_671	29953960	Homo sapiens	Exosomes derived from calcium oxalate-exposed macrophages enhance IL-8 production from renal cells, neutrophil migration and crystal invasion through extracellular matrix.	Macrophages	Protein	Microfiltration Differential centrifugation Ultracentrifugation	Exosomes
37	Vesiclepedia_583	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Brain cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
38	Vesiclepedia_366	12414662	Homo sapiens	Extracellular membrane vesicles from tumor cells promote angiogenesis via sphingomyelin.	Endothelial cells	Lipids	-	Membrane vesicles
39	Vesiclepedia_940	29207636	Homo sapiens	Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer.	Urine	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
40	Vesiclepedia_164	21864488	Homo sapiens	Marrow cell genetic phenotype change induced by human lung cancer cells	Lung cancer cells	mRNA	Differential centrifugation Ultracentrifugation	Microvesicles
41	Vesiclepedia_657	28753793	Homo sapiens	MicroRNAs in Serum Exosomes as Potential Biomarkers in Clear-cell Renal Cell Carcinoma.	Serum	miRNA	Total Exosome Isolation Kit Differential centrifugation Ultracentrifugation Immunobeads (EpCAM)	Exosomes
42	Vesiclepedia_986	25261472	Homo sapiens	Complex N-linked glycans serve as a determinant for exosome/microvesicle cargo recruitment.	Melanoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes/Microvesicles
43	Vesiclepedia_653	28290293	Homo sapiens	Comparative proteomic analysis of milk-derived exosomes in human and bovine colostrum and mature milk samples by iTRAQ-coupled LC-MS/MS.	Breast milk	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Exosomes
44	Vesiclepedia_844	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
45	Vesiclepedia_399	19530224	Homo sapiens	Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes.	Keratinocytes	Protein	-	Exosomes
46	Vesiclepedia_527	23660474	Homo sapiens	Heterogeneity in neutrophil microparticles reveals distinct proteome and functional properties.	Neutrophils	Protein	-	Microparticles
47	Vesiclepedia_700	28811610	Homo sapiens	Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA.	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Microvesicles
48	Vesiclepedia_1040	27770278	Homo sapiens	Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease.	Glioblastoma cells	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Extracellular vesicles
49	Vesiclepedia_547	24009880	Homo sapiens	Characterization of mRNA and microRNA in human mast cell-derived exosomes and their transfer to other mast cells and blood CD34 progenitor cells.	Mast cells	miRNA	-	Exosomes/Extracellular vesicles
50	Vesiclepedia_550	24009881	Homo sapiens	Quantitative proteomics of extracellular vesicles derived from human primary and metastatic colorectal cancer cells.	Colorectal cancer cells	Protein	-	Exosomes/Extracellular vesicles/Microvesicles/Ectosomes
51	Vesiclepedia_922	25483805	Homo sapiens	Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties	Embryonic kidney cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
52	Vesiclepedia_1129	23954818	Homo sapiens	Qualitative changes in the proteome of extracellular vesicles accompanying cancer cell transition to mesenchymal state.	Squamous carcinoma cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
53	Vesiclepedia_861	25776846	Homo sapiens	Human thymic epithelial primary cells produce exosomes carrying tissue-restricted antigens	Epithelial cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
54	Vesiclepedia_895	24946052	Homo sapiens	Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment	Lung cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
55	Vesiclepedia_200	21606166	Homo sapiens	Blast-derived microvesicles in sera from patients with acute myeloid leukemia suppress natural killer cell function via membrane-associated transforming growth factor-beta1	Serum	Protein	Size exclusion chromatography Ultracentrifugation	Microvesicles
56	Vesiclepedia_1079	25104112	Homo sapiens	Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy.	Plasma	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Exosomes
57	Vesiclepedia_138	22723089	Homo sapiens	Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes.	Prostate cancer cells	Protein	Sucrose density gradient	Exosomes
58	Vesiclepedia_480	23161513	Homo sapiens	Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.	Colorectal cancer cells	Protein	-	Exosomes
59	Vesiclepedia_1120	24347249	Homo sapiens	Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation ExoQuick	Exosomes
60	Vesiclepedia_720	26148937	Homo sapiens	Proteomics profiling of cholangiocarcinoma exosomes: A potential role of oncogenic protein transferring in cancer progression.	Cholangiocytes	Protein	Differential centrifugation Ultracentrifugation Filtration	Exosomes
61	Vesiclepedia_1182	28684402	Homo sapiens	BRAFV600 inhibition alters the microRNA cargo in the vesicular secretome of malignant melanoma cells	Melanoma cells	miRNA	Differential centrifugation Filtration Ultracentrifugation	Extracellular vesicles
62	Vesiclepedia_998	24355714	Homo sapiens	Proteomic analysis and immune properties of exosomes released by macrophages infected with Mycobacterium avium.	Leukemia cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
63	Vesiclepedia_381	18346024	Homo sapiens	The proteome of red cell membranes and vesicles during storage in blood bank conditions.	Red blood cells	Protein	-	Microvesicles/Nanovesicles
64	Vesiclepedia_495	23344721	Homo sapiens	miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.	Glioblastoma cells	mRNA	-	Microvesicles
65	Vesiclepedia_981	25458527	Homo sapiens	Benchtop isolation and characterization of functional exosomes by sequential filtration	Breast cancer cells	Protein	Sequential filtration	Exosomes
66	Vesiclepedia_275	12021310	Homo sapiens	Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles	Melanoma cells	Protein	Differential centrifugation Ultracentrifugation	Microvesicles
67	Vesiclepedia_153	22022598	Homo sapiens	Syncytiotrophoblast microvesicles released from pre-eclampsia placentae exhibit increased tissue factor activity	Placenta	Protein	Differential centrifugation	Microvesicles
68	Vesiclepedia_158	21630462	Homo sapiens	Proteomic analysis of microvesicles derived from human colorectal cancer ascites	Ascites	Protein	Differential centrifugation Sucrose density gradient OptiPrep density gradient	Microvesicles
69	Vesiclepedia_1078	25104112	Homo sapiens	Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy.	Plasma	miRNA	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Exosomes
70	Vesiclepedia_1204	27780738	Homo sapiens	Next-generation sequencing-based small RNA profiling of cerebrospinal fluid exosomes.	Serum	miRNA	Differential centrifugation Ultracentrifugation	Exosomes
71	Vesiclepedia_990	25261472	Homo sapiens	Complex N-linked glycans serve as a determinant for exosome/microvesicle cargo recruitment.	Melanoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes/Microvesicles
72	Vesiclepedia_306	16342139	Homo sapiens	Proteomic analysis of malignant lymphocyte membrane microparticles using double ionization coverage optimization	T cells	Protein	Differential centrifugation	Microparticles
73	Vesiclepedia_1018	22399603	Homo sapiens	Proteomic analysis of exosome-like vesicles derived from breast cancer cells.	Breast cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
74	Vesiclepedia_591	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Colorectal cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
75	Vesiclepedia_86	20949044	Homo sapiens	Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line	Colorectal cancer cells	miRNA	Differential centrifugation Filtration Ultracentrifugation	Exosomes
76	Vesiclepedia_18	11907077	Homo sapiens	TCR activation of human T cells induces the production of exosomes bearing the TCR/CD3/zeta complex.	T cells	Protein	Filtration Ultracentrifugation	Exosomes
77	Vesiclepedia_296	12796750	Homo sapiens	High levels of circulating endothelial microparticles in patients with acute coronary syndromes	Plasma	Protein	Differential centrifugation FACS	Microparticles
78	Vesiclepedia_969	25844599	Homo sapiens	Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.	Serum	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
79	Vesiclepedia_152	22064971	Homo sapiens	Oxidized low-density lipoprotein-dependent platelet-derived microvesicles trigger procoagulant effects and amplify oxidative stress	Platelets	Protein	Differential centrifugation	Microvesicles
80	Vesiclepedia_72	19801663	Homo sapiens	Microenvironmental pH is a key factor for exosome traffic in tumor cells.	Melanoma cells	Protein Lipids	Differential centrifugation	Exosomes
81	Vesiclepedia_945	29207636	Homo sapiens	Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer.	Urine	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
82	Vesiclepedia_510	23521563	Homo sapiens	First identification of Ewing's sarcoma-derived extracellular vesicles and exploration of their biological and potential diagnostic implications.	Ewing's sarcoma cells	mRNA	-	Exosomes/Extracellular vesicles
83	Vesiclepedia_24	11231627	Homo sapiens	Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming.	Melanoma cells	Protein	Differential centrifugation Sucrose density gradient	Exosomes
84	Vesiclepedia_1254	24468161	Homo sapiens	Molecular characterization of exosome-like vesicles from breast cancer cells.	Breast cancer cells	Protein miRNA	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
85	Vesiclepedia_1257	24400796	Homo sapiens	Exosomal proteins in the aqueous humor as novel biomarkers in patients with neovascular age-related macular degeneration.	Retinal pigment epithelial cells	Protein	ExoQuick	Exosomes
86	Vesiclepedia_166	21864488	Homo sapiens	Marrow cell genetic phenotype change induced by human lung cancer cells	Lung cancer cells	mRNA	Differential centrifugation Ultracentrifugation	Microvesicles
87	Vesiclepedia_402	19548909	Homo sapiens	Differential stimulation of monocytic cells results in distinct populations of microparticles.	Monocytes	Protein	-	Microparticles
88	Vesiclepedia_1130	23954818	Homo sapiens	Qualitative changes in the proteome of extracellular vesicles accompanying cancer cell transition to mesenchymal state.	Squamous carcinoma cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
89	Vesiclepedia_300	19234131	Homo sapiens	Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR	Epidermoid carcinoma cells	Protein	Differential centrifugation	Microvesicles
90	Vesiclepedia_81	20458337	Homo sapiens	MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 3	B cells	Protein	Differential centrifugation Sucrose density gradient Immunobeads (MHC Class II)	Exosomes
91	Vesiclepedia_335	20976003	Homo sapiens	Selective release of microRNA species from normal and malignant mammary epithelial cells	Breast cancer cells	Protein miRNA	Differential centrifugation Filtration	Exosomes
92	Vesiclepedia_332	19627513	Homo sapiens	Exosomes from human saliva as a source of microRNA biomarkers	Saliva	miRNA	Differential centrifugation Ultracentrifugation	Exosomes
93	Vesiclepedia_260	10888925	Homo sapiens	Transfer of the chemokine receptor CCR5 between cells by membrane-derived microparticles: a mechanism for cellular human immunodeficiency virus 1 infection	Mononuclear cells	Protein	Differential centrifugation Filtration	Microparticles
94	Vesiclepedia_323	20304794	Homo sapiens	Functional delivery of viral miRNAs via exosomes	B cells	Protein	Differential centrifugation	Exosomes
95	Vesiclepedia_1077	25104112	Homo sapiens	Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy.	Plasma	miRNA	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Exosomes
96	Vesiclepedia_535	23818640	Homo sapiens	Modulation of B-cell exosome proteins by gamma herpesvirus infection.	B cells	Protein	-	Exosomes/Microvesicles/Oncosomes/Microparticles
97	Vesiclepedia_270	10903724	Homo sapiens	Follicular dendritic cells carry MHC class II-expressing microvesicles at their surface	Dendritic cells	Protein	-	Microvesicles
98	Vesiclepedia_408	20031610	Homo sapiens	Proteomics, metabolomics, and immunomics on microparticles derived from human atherosclerotic plaques.	Carotid atherosclerotic plaques	Metabolites	-	Microparticles
99	Vesiclepedia_1050	28842968	Homo sapiens	Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles.	Colorectal cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
100	Vesiclepedia_1250	24939845	Homo sapiens	Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein.	Leukemia cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
101	Vesiclepedia_566	26858453	Homo sapiens	Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes	Dendritic cells	Protein	Differential centrifugation Ultracentrifugation Immunobeads (Igg1 PD)	Extracellular vesicles
102	Vesiclepedia_454	22669077	Homo sapiens	The proteome of erythrocyte-derived microparticles from plasma: new clues for erythrocyte aging and vesiculation.	Plasma	Protein	-	Microparticles
103	Vesiclepedia_569	26858453	Homo sapiens	Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes	Dendritic cells	Protein	Differential centrifugation Ultracentrifugation Immunobeads (CD9 FT)	Extracellular vesicles
104	Vesiclepedia_710	28811610	Homo sapiens	Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA.	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
105	Vesiclepedia_1152	22057275	Homo sapiens	Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease.	Neuroblastoma cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
106	Vesiclepedia_748	29988836	Homo sapiens	Ultrafiltration and size exclusion chromatography combined with asymmetrical-flow field-flow fractionation for the isolation and characterisation of extracellular vesicles from urine	Urine	Protein	Filtration Size exclusion chromatography	Extracellular vesicles
107	Vesiclepedia_932	29207636	Homo sapiens	Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer.	Bladder cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
108	Vesiclepedia_82	20949044	Homo sapiens	Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line	Stomach cancer cells	Protein miRNA	Differential centrifugation Filtration Ultracentrifugation	Exosomes
109	Vesiclepedia_41	15908444	Homo sapiens	Exosomal-like vesicles are present in human blood plasma.	Mast cells	Protein	Differential centrifugation Filtration Sucrose density gradient	Exosomes
110	Vesiclepedia_1263	24371517	Homo sapiens	Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients.	Urine	Protein	Differential centrifugation Ultracentrifugation	Exosomes
111	Vesiclepedia_897	26100252	Homo sapiens	Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts	Chronic lymphocytic leukemia cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
112	Vesiclepedia_741	25157233	Homo sapiens	Extravillous trophoblast cells-derived exosomes promote vascular smooth muscle cell migration.	Placenta	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
113	Vesiclepedia_1012	22711894	Homo sapiens	Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages.	Macrophages	Protein	Differential centrifugation Filtration Ultracentrifugation	Microvesicles/Exosomes
114	Vesiclepedia_1016	22711894	Homo sapiens	Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages.	Macrophages	Protein Lipids	Differential centrifugation Filtration Ultracentrifugation	Exosomes
115	Vesiclepedia_1023	22327366	Homo sapiens	Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs.	Vascular endothelial cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
116	Vesiclepedia_108	21601258	Homo sapiens	Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage.	Ascites	Protein miRNA	Differential centrifugation Sucrose density gradient Immunobeads (EpCAM, CD24)	Exosomes
117	Vesiclepedia_71	19801663	Homo sapiens	Microenvironmental pH is a key factor for exosome traffic in tumor cells.	Melanoma cells	Protein Lipids	Differential centrifugation Sucrose density gradient	Exosomes
118	Vesiclepedia_619	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Melanoma cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
119	Vesiclepedia_79	20458337	Homo sapiens	MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 1	B cells	Protein	Differential centrifugation Sucrose density gradient Immunobeads (MHC Class II)	Exosomes
120	Vesiclepedia_719	26148937	Homo sapiens	Proteomics profiling of cholangiocarcinoma exosomes: A potential role of oncogenic protein transferring in cancer progression.	Cholangiocarcinoma cells	Protein	Differential centrifugation Ultracentrifugation Filtration	Exosomes
121	Vesiclepedia_1199	27883272	Homo sapiens	Circulating adipocyte-derived exosomal MicroRNAs associated with decreased insulin resistance after gastric bypass.	Serum	miRNA Metabolites	ExoQuick	Exosomes
122	Vesiclepedia_320	20615901	Homo sapiens	Export of microRNAs and microRNA-protective protein by mammalian cells	Epithelial cells	miRNA	Differential centrifugation	Microvesicles
123	Vesiclepedia_1244	25167841	Homo sapiens	Antibody-coupled monolithic silica microtips for highthroughput molecular profiling of circulating exosomes.	Serum	Protein	CD9 antibody to Mass Spectrometric Immunoassay monolith pipette tips	Exosomes
124	Vesiclepedia_853	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
125	Vesiclepedia_1213	29127410	Homo sapiens	Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies.	Bronchial epithelial cells	Protein	Ultracentrifugation	Extracellular vesicles
126	Vesiclepedia_693	28170197	Homo sapiens	Enhanced Cardioprotection by Human Endometrium Mesenchymal Stem Cells Driven by Exosomal MicroRNA-21	Bone marrow mesenchymal stem cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
127	Vesiclepedia_1063	30006486	Homo sapiens	The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells.	Astrocytoma cells	Protein	Filtration Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
128	Vesiclepedia_555	24046871	Homo sapiens	Molecular lipidomics of exosomes released by PC-3 prostate cancer cells.	Prostate cancer cells	Lipids	-	Exosomes/Microvesicles
129	Vesiclepedia_724	25471207	Homo sapiens	Intraluminal proteome and peptidome of human urinary extracellular vesicles.	Urine	Protein	Differential centrifugation Hydrostatic filtration dialysis Ultrafiltration	Exosomes
130	Vesiclepedia_388	18570454	Homo sapiens	Proteomic analysis of exosomes from human neural stem cells by flow field-flow fractionation and nanoflow liquid chromatography-tandem mass spectrometry.	Neural stem cells	Protein	-	Exosomes/Membrane vesicles
131	Vesiclepedia_935	29207636	Homo sapiens	Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer.	Urine	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
132	Vesiclepedia_798	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Embryonic kidney cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
133	Vesiclepedia_486	23230278	Homo sapiens	Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids.	Colorectal cancer cells	Protein	-	Exosomes/Extracellular vesicles/Microvesicles
134	Vesiclepedia_274	12021310	Homo sapiens	Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles	Melanoma cells	Protein	Differential centrifugation Ultracentrifugation	Microvesicles
135	Vesiclepedia_1149	22807456	Homo sapiens	Quantitative proteomic analysis of exosomes from HIV-1-infected lymphocytic cells.	Lymphocytes	Protein	Differential centrifugation Ultracentrifugation	Exosomes
136	Vesiclepedia_31	10572093	Homo sapiens	Activated platelets release two types of membrane vesicles: microvesicles by surface shedding and exosomes derived from exocytosis of multivesicular bodies and alpha-granules.	Platelets	Protein	Differential centrifugation Sucrose density gradient	Exosomes
137	Vesiclepedia_802	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
138	Vesiclepedia_740	25157233	Homo sapiens	Extravillous trophoblast cells-derived exosomes promote vascular smooth muscle cell migration.	Placenta choriocarcinoma cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
139	Vesiclepedia_746	29988836	Homo sapiens	Ultrafiltration and size exclusion chromatography combined with asymmetrical-flow field-flow fractionation for the isolation and characterisation of extracellular vesicles from urine	Urine	Protein	Filtration Size exclusion chromatography	Extracellular vesicles
140	Vesiclepedia_898	26100252	Homo sapiens	Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts	Chronic lymphocytic leukemia cells	miRNA	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
141	Vesiclepedia_78	20224111	Homo sapiens	Proteomics analysis of bladder cancer exosomes.	Urine	Protein	Differential centrifugation Sucrose density gradient	Exosomes
142	Vesiclepedia_288	12196479	Homo sapiens	Type 1 and type 2 diabetic patients display different patterns of cellular microparticles	Plasma	Protein Lipids	Differential centrifugation FACS	Microparticles
143	Vesiclepedia_231	2294986	Homo sapiens	Direct detection of activated platelets and platelet-derived microparticles in humans	Plasma	Protein	FACS	Microparticles
144	Vesiclepedia_496	23344721	Homo sapiens	miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.	Melanoma cells	mRNA	-	Microvesicles
145	Vesiclepedia_22	15940614	Homo sapiens	Human colorectal cancer cells induce T-cell death through release of proapoptotic microvesicles: role in immune escape.	Colorectal cancer cells	Protein	Differential centrifugation	Exosomes
146	Vesiclepedia_215	21364924	Homo sapiens	Thermal- and oxidative stress causes enhanced release of NKG2D ligand-bearing immunosuppressive exosomes in leukemia/lymphoma T and B cells	B cells	Protein	Differential centrifugation Ultracentrifugation Filtration Sucrose density gradient FACS	Exosomes
147	Vesiclepedia_711	28811610	Homo sapiens	Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA.	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Microvesicles
148	Vesiclepedia_294	2071604	Homo sapiens	Evidence that agonist-induced activation of calpain causes the shedding of procoagulant-containing microvesicles from the membrane of aggregating platelets	Platelets	Protein	Differential centrifugation Filtration	Microvesicles
149	Vesiclepedia_1194	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
150	Vesiclepedia_1141	23454749	Homo sapiens	BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression.	Bone marrow mesenchymal stromal cells	Protein	Differential centrifugation Ultracentrifugation Filtration ExoQuick	Exosomes
151	Vesiclepedia_1267	24218614	Homo sapiens	Unexpected gain of function for the scaffolding protein plectin due to mislocalization in pancreatic cancer.	Pancreatic adenocarcinoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
152	Vesiclepedia_588	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Colorectal cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
153	Vesiclepedia_236	10648405	Homo sapiens	Cellular origin and procoagulant properties of microparticles in meningococcal sepsis	Plasma	Protein	Differential centrifugation FACS	Microparticles
154	Vesiclepedia_624	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Melanoma cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
155	Vesiclepedia_1108	24391718	Homo sapiens	Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.	Prostate epithelial cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
156	Vesiclepedia_278	10233897	Homo sapiens	Elevated levels of circulating procoagulant microparticles in patients with paroxysmal nocturnal hemoglobinuria and aplastic anemia	Platelets	Protein Lipids	Differential centrifugation FACS	Microparticles
157	Vesiclepedia_226	12514112	Homo sapiens	Intravascular tissue factor initiates coagulation via circulating microvesicles and platelets	Platelets	Protein	Differential centrifugation	Microvesicles
158	Vesiclepedia_406	19806257	Homo sapiens	Proteomic and functional characterisation of platelet microparticle size classes.	Platelets	Protein	-	Microparticles
159	Vesiclepedia_281	15499615	Homo sapiens	Microvesicles derived from activated platelets induce metastasis and angiogenesis in lung cancer	Lung cancer cells	mRNA	Differential centrifugation Ultracentrifugation	Exosomes
160	Vesiclepedia_88	20949044	Homo sapiens	Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line	Stomach cancer cells	Protein miRNA	Differential centrifugation Filtration Ultracentrifugation	Exosomes
161	Vesiclepedia_325	19289371	Homo sapiens	Exosomal microRNA: a diagnostic marker for lung cancer	Plasma	miRNA	Size exclusion chromatography Immunobeads (EpCAM)	Exosomes
162	Vesiclepedia_1011	23185418	Homo sapiens	Improved flow cytometric assessment reveals distinct microvesicle (cell-derived microparticle) signatures in joint diseases.	Synovial fluid	Protein	Filtration Ultracentrifugation	Microvesicles
163	Vesiclepedia_1069	29937354	Homo sapiens	Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors.	Glioblastoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
164	Vesiclepedia_80	20458337	Homo sapiens	MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis -Sample 2	B cells	Protein	Differential centrifugation Sucrose density gradient Immunobeads (MHC Class II)	Exosomes
165	Vesiclepedia_793	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Embryonic kidney cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
166	Vesiclepedia_233	7697722	Homo sapiens	Secretory phospholipase A2 generates the novel lipid mediator lysophosphatidic acid in membrane microvesicles shed from activated cells	Inflammatory fluid	Lipids	Differential centrifugation	Microvesicles
167	Vesiclepedia_562	26858453	Homo sapiens	Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes	Dendritic cells	Protein	Differential centrifugation Ultracentrifugation OptiPrep density gradient	Microvesicles
168	Vesiclepedia_279	16192427	Homo sapiens	Circulating endothelial microparticles are associated with vascular dysfunction in patients with end-stage renal failure	Plasma	Protein	Differential centrifugation FACS	Microparticles
169	Vesiclepedia_1219	27872147	Homo sapiens	Primary Human and Rat .-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity.	Islets	Protein	Differential centrifugation Ultracentrifugation	Exosomes
170	Vesiclepedia_317	19266099	Homo sapiens	Transfer of microRNAs by embryonic stem cell microvesicles	Embryonic stem cells	mRNA miRNA snRNA	Differential centrifugation	Microvesicles
171	Vesiclepedia_1093	25065644	Homo sapiens	Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells.	Duodenal cancer cells	Protein	Differential centrifugation Filtration Ultrafiltration	Exosomes
172	Vesiclepedia_412	20156641	Homo sapiens	Proteomics of microparticles after deep venous thrombosis.	Plasma	Protein	-	Membrane vesicles/Microparticles
173	Vesiclepedia_461	22848702	Homo sapiens	Medulloblastoma exosome proteomics yield functional roles for extracellular vesicles.	Medulloblastoma cells	Protein	-	Exosomes/Membrane vesicles/Extracellular vesicles
174	Vesiclepedia_429	21595033	Homo sapiens	Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.	Urine	Protein	-	Exosomes
175	Vesiclepedia_673	29953960	Homo sapiens	Exosomes derived from calcium oxalate-exposed macrophages enhance IL-8 production from renal cells, neutrophil migration and crystal invasion through extracellular matrix.	Macrophages	Protein	Microfiltration Differential centrifugation Ultracentrifugation	Exosomes
176	Vesiclepedia_1062	30006486	Homo sapiens	The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells.	Astrocytoma cells	Protein	Filtration Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
177	Vesiclepedia_674	29953960	Homo sapiens	Exosomes derived from calcium oxalate-exposed macrophages enhance IL-8 production from renal cells, neutrophil migration and crystal invasion through extracellular matrix.	Macrophages	Protein	Microfiltration Differential centrifugation Ultracentrifugation	Exosomes
178	Vesiclepedia_131	19188015	Homo sapiens	Systemic presence and tumor-growth promoting effect of ovarian carcinoma released exosomes	Ascites	Protein Lipids	Differential centrifugation Sucrose density gradient	Exosomes
179	Vesiclepedia_617	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Melanoma cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
180	Vesiclepedia_27	19109410	Homo sapiens	Proteomic and immunologic analyses of brain tumor exosomes.	Medulloblastoma cells	Protein	Differential centrifugation Sucrose density gradient	Exosomes
181	Vesiclepedia_526	23660474	Homo sapiens	Heterogeneity in neutrophil microparticles reveals distinct proteome and functional properties.	Neutrophils	Protein	-	Microparticles
182	Vesiclepedia_1125	24347249	Homo sapiens	Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation ExoQuick	Exosomes
183	Vesiclepedia_1195	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
184	Vesiclepedia_791	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Embryonic kidney cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
185	Vesiclepedia_534	23818640	Homo sapiens	Modulation of B-cell exosome proteins by gamma herpesvirus infection.	B cells	Protein	-	Exosomes/Microvesicles/Oncosomes/Microparticles
186	Vesiclepedia_248	15741221	Homo sapiens	Tissue-factor-bearing microvesicles arise from lipid rafts and fuse with activated platelets to initiate coagulation	Monocytic leukemia cells	Protein	Differential centrifugation	Microvesicles
187	Vesiclepedia_198	21555566	Homo sapiens	Multiple recognition assay reveals prostasomes as promising plasma biomarkers for prostate cancer	Plasma	Protein	Differential centrifugation Ultracentrifugation Gel chromatography	Microvesicles
188	Vesiclepedia_927	25483805	Homo sapiens	Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties	Embryonic kidney cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
189	Vesiclepedia_56	12147373	Homo sapiens	Malignant effusions and immunogenic tumour-derived exosomes.	Ascites	Protein	Differential centrifugation Sucrose density gradient	Exosomes
190	Vesiclepedia_1128	23954818	Homo sapiens	Qualitative changes in the proteome of extracellular vesicles accompanying cancer cell transition to mesenchymal state.	Squamous carcinoma cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
191	Vesiclepedia_169	21859146	Homo sapiens	Identification of a conserved glycan signature for microvesicles	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Microvesicles
192	Vesiclepedia_455	22682234	Homo sapiens	Microparticle conferred microRNA profiles - implications in the transfer and dominance of cancer traits.	Leukemia cells	miRNA	-	Membrane vesicles/Microparticles
193	Vesiclepedia_992	24434149	Homo sapiens	In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome.	Ovarian cancer cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
194	Vesiclepedia_660	29964051	Homo sapiens	Cell-free therapy based on adipose tissue stem cell-derived exosomes promotes wound healing via the PI3K/Akt signaling pathway	Adipose tissue-derived stem cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
195	Vesiclepedia_577	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Breast cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
196	Vesiclepedia_631	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Ovarian cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
197	Vesiclepedia_179	20686450	Homo sapiens	Comparison of three methods for isolation of urinary microvesicles to identify biomarkers of nephrotic syndrome	Urine	Protein	Differential centrifugation Ultracentrifugation	Microvesicles
198	Vesiclepedia_1260	24371517	Homo sapiens	Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
199	Vesiclepedia_430	21595033	Homo sapiens	Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.	Urine	Protein	-	Exosomes
200	Vesiclepedia_568	26858453	Homo sapiens	Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes	Dendritic cells	Protein	Differential centrifugation Ultracentrifugation Immunobeads (CD9 PD)	Extracellular vesicles
201	Vesiclepedia_1004	23463506	Homo sapiens	The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes.	T cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
202	Vesiclepedia_701	28811610	Homo sapiens	Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA.	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Microvesicles
203	Vesiclepedia_1245	25167841	Homo sapiens	Antibody-coupled monolithic silica microtips for highthroughput molecular profiling of circulating exosomes.	Serum	Protein	CD9 antibody to Mass Spectrometric Immunoassay monolith pipette tips	Exosomes
204	Vesiclepedia_481	23161513	Homo sapiens	Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.	Colorectal cancer cells	Protein	-	Exosomes
205	Vesiclepedia_441	22251860	Homo sapiens	RNA expression patterns in serum microvesicles from patients with glioblastoma multiforme and controls.	Serum	mRNA	-	Exosomes/Microvesicles
206	Vesiclepedia_17	11907077	Homo sapiens	TCR activation of human T cells induces the production of exosomes bearing the TCR/CD3/zeta complex.	T cells	Protein	Filtration Ultracentrifugation	Exosomes
207	Vesiclepedia_87	20949044	Homo sapiens	Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line	Colorectal cancer cells	miRNA	Differential centrifugation Filtration Ultracentrifugation	Exosomes
208	Vesiclepedia_707	28811610	Homo sapiens	Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA.	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
209	Vesiclepedia_528	23767874	Homo sapiens	Biochemical and biological characterization of exosomes containing prominin-1/CD133.	Melanoma cells	Lipids	-	Exosomes/Microvesicles
210	Vesiclepedia_851	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
211	Vesiclepedia_1226	26154623	Homo sapiens	Size-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals	Plasma	Protein	Size exclusion chromatography	Extracellular vesicles
212	Vesiclepedia_54	14975938	Homo sapiens	Proteomic analysis of exosomes isolated from human malignant pleural effusions.	Malignant pleural effusions	Protein	Differential centrifugation Sucrose density gradient	Exosomes
213	Vesiclepedia_326	20428099	Homo sapiens	Nucleic acids within urinary exosomes/microvesicles are potential biomarkers for renal disease	Urine	mRNA	Differential centrifugation Ultracentrifugation	Microvesicles
214	Vesiclepedia_476	23056502	Homo sapiens	Identifying mRNA, MicroRNA and Protein Profiles of Melanoma Exosomes.	Melanoma cells	miRNA	-	Exosomes
215	Vesiclepedia_1156	21212511	Homo sapiens	Proteomic analysis of two types of exosomes in human whole saliva.	Saliva	Protein	Differential centrifugation Filtration Ultracentrifugation Gel filtration	Exosomes
216	Vesiclepedia_178	20686450	Homo sapiens	Comparison of three methods for isolation of urinary microvesicles to identify biomarkers of nephrotic syndrome	Urine	Protein	Differential centrifugation Ultrafiltration	Microvesicles
217	Vesiclepedia_1155	21212511	Homo sapiens	Proteomic analysis of two types of exosomes in human whole saliva.	Saliva	Protein	Differential centrifugation Filtration Ultracentrifugation Gel filtration	Exosomes
218	Vesiclepedia_880	29955024	Homo sapiens	Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells	Myeloid leukemia cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
219	Vesiclepedia_893	24946052	Homo sapiens	Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment	Lung cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
220	Vesiclepedia_726	25471207	Homo sapiens	Intraluminal proteome and peptidome of human urinary extracellular vesicles.	Urine	Protein	Differential centrifugation Hydrostatic filtration dialysis Ultrafiltration	Exosomes
221	Vesiclepedia_384	18482993	Homo sapiens	Protein composition of human epididymosomes collected during surgical vasectomy reversal: a proteomic and genomic approach.	Epididymal fluid	Protein	-	Prostasomes
222	Vesiclepedia_123	21235781	Homo sapiens	Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages.	Plasma	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
223	Vesiclepedia_1109	24391718	Homo sapiens	Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.	Prostate epithelial cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
224	Vesiclepedia_794	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Embryonic kidney cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
225	Vesiclepedia_1208	29127410	Homo sapiens	Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies.	Bronchial epithelial cells	Protein	Ultrafiltration Size exclusion chromatography	Extracellular vesicles
226	Vesiclepedia_109	21601258	Homo sapiens	Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage.	Malignant pleural effusions	Protein miRNA	Differential centrifugation Sucrose density gradient Immunobeads (EpCAM)	Exosomes
227	Vesiclepedia_795	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Embryonic kidney cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
228	Vesiclepedia_616	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Lung cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
229	Vesiclepedia_259	18425114	Homo sapiens	Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells	Glioma cells	Protein	Differential centrifugation Ultracentrifugation	Microvesicles
230	Vesiclepedia_860	25776846	Homo sapiens	Human thymic epithelial primary cells produce exosomes carrying tissue-restricted antigens	Epithelial cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
231	Vesiclepedia_699	28811610	Homo sapiens	Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA.	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
232	Vesiclepedia_890	24946052	Homo sapiens	Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment	Lung cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
233	Vesiclepedia_630	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Ovarian cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
234	Vesiclepedia_1027	24211404	Homo sapiens	Diabetic nephropathy induces changes in the proteome of human urinary exosomes as revealed by label-free comparative analysis.	Urine	Protein	Ultracentrifugation ExoQuick	Exosomes
235	Vesiclepedia_1247	25167841	Homo sapiens	Antibody-coupled monolithic silica microtips for highthroughput molecular profiling of circulating exosomes.	Serum	Protein	CD9 antibody to Mass Spectrometric Immunoassay monolith pipette tips	Exosomes
236	Vesiclepedia_156	21939504	Homo sapiens	Microvesicles secreted by macrophages shuttle invasion-potentiating microRNAs into breast cancer cells	Macrophages	miRNA	Differential centrifugation Filtration Ultracentrifugation	Microvesicles
237	Vesiclepedia_1112	24391718	Homo sapiens	Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
238	Vesiclepedia_224	10393703	Homo sapiens	In vitro generation of endothelial microparticles and possible prothrombotic activity in patients with lupus anticoagulant	Plasma	Protein	Differential centrifugation	Microparticles
239	Vesiclepedia_256	9126269	Homo sapiens	Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations	Burkitt's lymphoma	Protein	Differential centrifugation Sucrose density gradient	Microvesicles
240	Vesiclepedia_1143	23454749	Homo sapiens	BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression.	Bone marrow mesenchymal stromal cells	Protein	Differential centrifugation Ultracentrifugation Filtration ExoQuick	Exosomes
241	Vesiclepedia_393	19369228	Homo sapiens	Proteomic analysis reveals presence of platelet microparticles in endothelial progenitor cell cultures.	Endothelial cells	Protein	-	Microparticles
242	Vesiclepedia_463	22849433	Homo sapiens	Selective extracellular vesicle-mediated export of an overlapping set of microRNAs from multiple cell types.	Embryonic kidney cells	miRNA	-	Extracellular vesicles
243	Vesiclepedia_999	24355714	Homo sapiens	Proteomic analysis and immune properties of exosomes released by macrophages infected with Mycobacterium avium.	Leukemia cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
244	Vesiclepedia_43	17076679	Homo sapiens	Specific isolation of placenta-derived exosomes from the circulation of pregnant women and their immunoregulatory consequences.	Plasma	Protein	Size exclusion chromatography Ultracentrifugation Immunobeads (CD3, CD19, CD56, CD83, PLAP)	Exosomes
245	Vesiclepedia_752	29963269	Homo sapiens	Mining of potential microRNAs with clinical correlation - regulation of syndecan-1 expression by miR-122-5p altered mobility of breast cancer cells and possible correlation with liver injury	Hepatoma cells	Protein	Total Exosome Isolation Kit Differential centrifugation	Exosomes
246	Vesiclepedia_839	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
247	Vesiclepedia_732	25359493	Homo sapiens	Proteomic signatures of extracellular vesicles secreted by nonmineralizing and mineralizing human osteoblasts and stimulation of tumor cell growth.	Osteoblasts	Protein	Differential centrifugation Ultracentrifugation	Matrix vesicles
248	Vesiclepedia_955	27601599	Homo sapiens	Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components.	Breast milk	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
249	Vesiclepedia_232	7697722	Homo sapiens	Secretory phospholipase A2 generates the novel lipid mediator lysophosphatidic acid in membrane microvesicles shed from activated cells	Red blood cells	Lipids	Differential centrifugation	Microvesicles
250	Vesiclepedia_974	22808001	Homo sapiens	Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment.	Serum	Protein	Filtration ExoQuick	Exosomes
251	Vesiclepedia_117	21505438	Homo sapiens	Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells.	Dendritic cells	Protein miRNA	Differential centrifugation Filtration Ultracentrifugation	Exosomes
252	Vesiclepedia_467	23000592	Homo sapiens	In-depth analysis of the secretome identifies three major independent secretory pathways in differentiating human myoblasts.	Neonatal myoblast cells	Protein	-	Microvesicles/Nanovesicles
253	Vesiclepedia_855	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
254	Vesiclepedia_91	21252909	Homo sapiens	Diacylglycerol kinase a regulates the formation and polarisation of mature multivesicular bodies involved in the secretion of Fas ligand-containing exosomes in T lymphocytes	T cells	Protein Lipids	Differential centrifugation Ultracentrifugation	Exosomes
255	Vesiclepedia_891	24946052	Homo sapiens	Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment	Lung cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
256	Vesiclepedia_877	29955024	Homo sapiens	Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells	Embryonic kidney cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
257	Vesiclepedia_1184	28684402	Homo sapiens	BRAFV600 inhibition alters the microRNA cargo in the vesicular secretome of malignant melanoma cells	Melanoma cells	miRNA	Differential centrifugation Filtration Ultracentrifugation	Extracellular vesicles
258	Vesiclepedia_578	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Breast cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
259	Vesiclepedia_656	28753793	Homo sapiens	MicroRNAs in Serum Exosomes as Potential Biomarkers in Clear-cell Renal Cell Carcinoma.	Serum	miRNA	Total Exosome Isolation Kit Differential centrifugation Ultracentrifugation Immunobeads (EpCAM)	Exosomes
260	Vesiclepedia_502	23436686	Homo sapiens	A comprehensive characterization of membrane vesicles released by autophagic human endothelial cells.	Endothelial cells	Protein	-	Membrane vesicles/Extracellular vesicles
261	Vesiclepedia_1258	24400796	Homo sapiens	Exosomal proteins in the aqueous humor as novel biomarkers in patients with neovascular age-related macular degeneration.	Aqueous humor	Protein	ExoQuick	Exosomes
262	Vesiclepedia_1038	29887978	Homo sapiens	Evaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing.	Serum	Protein miRNA	miRCURY Exosome Isolation Kit	Extracellular vesicles
263	Vesiclepedia_369	16212402	Homo sapiens	The platelet microparticle proteome.	Platelets	Protein	-	Microparticles
264	Vesiclepedia_952	27601599	Homo sapiens	Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components.	Breast milk	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
265	Vesiclepedia_1242	25261722	Homo sapiens	Inflammatory cytokines, interleukin-1 beta and tumor necrosis factor-alpha, upregulated in glioblastoma multiforme, raise the levels of CRYAB in exosomes secreted by U373 glioma cells.	Glioblastoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
266	Vesiclepedia_1067	29937354	Homo sapiens	Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors.	Glioblastoma cells	Protein	Differential centrifugation Filtration	Microvesicles
267	Vesiclepedia_512	23533145	Homo sapiens	In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.	Urine	Protein	-	Exosomes/Microvesicles
268	Vesiclepedia_1256	24400796	Homo sapiens	Exosomal proteins in the aqueous humor as novel biomarkers in patients with neovascular age-related macular degeneration.	Retinal pigment epithelial cells	Protein	ExoQuick	Exosomes
269	Vesiclepedia_991	25138791	Homo sapiens	The exocyst and regulatory GTPases in urinary exosomes.	Urine	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
270	Vesiclepedia_353	24115447	Homo sapiens	Comparative proteomics evaluation of plasma exosome isolation techniques and assessment of the stability of exosomes in normal human blood plasma	Plasma	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
271	Vesiclepedia_193	21575145	Homo sapiens	Microvesicle-mediated release of soluble LH/hCG receptor (LHCGR) from transfected cells and placenta explants	Placenta	Protein	Differential centrifugation Ultracentrifugation	Microvesicles
272	Vesiclepedia_1092	25065644	Homo sapiens	Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells.	Duodenal cancer cells	Protein	Differential centrifugation Filtration Ultrafiltration	Exosomes
273	Vesiclepedia_1071	29937354	Homo sapiens	Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors.	Glioblastoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
274	Vesiclepedia_1255	24468161	Homo sapiens	Molecular characterization of exosome-like vesicles from breast cancer cells.	Breast cancer cells	Protein miRNA	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
275	Vesiclepedia_792	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Embryonic kidney cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
276	Vesiclepedia_249	15741221	Homo sapiens	Tissue-factor-bearing microvesicles arise from lipid rafts and fuse with activated platelets to initiate coagulation	Monocytes	Protein	Differential centrifugation	Microvesicles
277	Vesiclepedia_1154	22057275	Homo sapiens	Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease.	Cerebrospinal fluid	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
278	Vesiclepedia_601	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Kidney cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
279	Vesiclepedia_1039	27770278	Homo sapiens	Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease.	Glioblastoma cells	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Extracellular vesicles
280	Vesiclepedia_165	21864488	Homo sapiens	Marrow cell genetic phenotype change induced by human lung cancer cells	Lung cancer cells	mRNA	Differential centrifugation Ultracentrifugation	Microvesicles
281	Vesiclepedia_1269	24218614	Homo sapiens	Unexpected gain of function for the scaffolding protein plectin due to mislocalization in pancreatic cancer.	Pancreatic adenocarcinoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
282	Vesiclepedia_458	22740476	Homo sapiens	Restoration of full-length APC protein in SW480 colon cancer cells induces exosome-mediated secretion of DKK-4.	Colorectal cancer cells	Protein	-	Exosomes
283	Vesiclepedia_261	12805058	Homo sapiens	Sickle blood contains tissue factor-positive microparticles derived from endothelial cells and monocytes	Plasma	Protein Lipids	Differential centrifugation Ultracentrifugation FACS	Microparticles
284	Vesiclepedia_285	12796750	Homo sapiens	High levels of circulating endothelial microparticles in patients with acute coronary syndromes	Plasma	Protein	Differential centrifugation FACS	Microparticles
285	Vesiclepedia_1176	29854963	Homo sapiens	Genome-wide Profiling of Urinary Extracellular Vesicle microRNAs Associated With Diabetic Nephropathy in Type 1 Diabetes.	Urine	miRNA	qEV size-exclusion column	Extracellular vesicles
286	Vesiclepedia_967	25844599	Homo sapiens	Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.	Serum	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
287	Vesiclepedia_102	21082674	Homo sapiens	Comprehensive analysis of low-abundance proteins in human urinary exosomes using peptide ligand library technology, peptide OFFGEL fractionation and nanoHPLC-chip-MS/MS.	Urine	Protein	Differential centrifugation Ultracentrifugation	Exosomes
288	Vesiclepedia_661	29956871	Homo sapiens	Expression analysis of extracellular microRNA in bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis	Bronchoalveolar lavage fluid	Protein	Differential centrifugation Ultracentrifugation Filtration	Exosomes
289	Vesiclepedia_1030	26378940	Homo sapiens	Redefining the Breast Cancer Exosome Proteome by Tandem Mass Tag Quantitative Proteomics and Multivariate Cluster Analysis.	Breast cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
290	Vesiclepedia_111	21601258	Homo sapiens	Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage.	Serum	Protein miRNA	Differential centrifugation Sucrose density gradient Immunobeads (CD24)	Exosomes
291	Vesiclepedia_987	25261472	Homo sapiens	Complex N-linked glycans serve as a determinant for exosome/microvesicle cargo recruitment.	Melanoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes/Microvesicles
292	Vesiclepedia_1091	25065644	Homo sapiens	Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells.	Duodenal cancer cells	Protein	Differential centrifugation Filtration Ultrafiltration	Exosomes
293	Vesiclepedia_1238	25329303	Homo sapiens	Rapid isolation of extracellular vesicles from cell culture and biological fluids using a synthetic peptide with specific affinity for heat shock proteins.	Urine	Protein	Ultracentrifugation	Extracellular vesicles
294	Vesiclepedia_76	20224111	Homo sapiens	Proteomics analysis of bladder cancer exosomes.	Bladder cancer cells	Protein	Differential centrifugation Sucrose density gradient	Exosomes
295	Vesiclepedia_1068	29937354	Homo sapiens	Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors.	Glioblastoma cells	Protein	Differential centrifugation Filtration	Microvesicles
296	Vesiclepedia_273	12021310	Homo sapiens	Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles	T cells	Protein	Differential centrifugation Ultracentrifugation	Microvesicles
297	Vesiclepedia_934	29207636	Homo sapiens	Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer.	Bladder cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
298	Vesiclepedia_25	15111327	Homo sapiens	Proteomic analysis of exosomes secreted by human mesothelioma cells.	Mesothelioma cells	Protein	Differential centrifugation	Exosomes
299	Vesiclepedia_180	20686450	Homo sapiens	Comparison of three methods for isolation of urinary microvesicles to identify biomarkers of nephrotic syndrome	Urine	Protein	Differential centrifugation Ultracentrifugation Size exclusion chromatography Filtration	Microvesicles
300	Vesiclepedia_144	22723089	Homo sapiens	Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes.	Prostate cancer cells	Protein	Sucrose density gradient	Exosomes
301	Vesiclepedia_755	29963269	Homo sapiens	Mining of potential microRNAs with clinical correlation - regulation of syndecan-1 expression by miR-122-5p altered mobility of breast cancer cells and possible correlation with liver injury	Hepatoma cells	miRNA	Total Exosome Isolation Kit Differential centrifugation	Exosomes
302	Vesiclepedia_114	21557262	Homo sapiens	Proteomic identification of exosomal LRG1: A potential urinary biomarker for detecting NSCLC.	Urine	Protein	Differential centrifugation Ultracentrifugation	Exosomes
303	Vesiclepedia_189	21741384	Homo sapiens	A filtration-based protocol to isolate human plasma membrane-derived vesicles and exosomes from blood plasma	Plasma	Protein	Differential centrifugation Filtration	Exosomes
304	Vesiclepedia_1095	24976626	Homo sapiens	Exosomal transfer from human renal proximal tubule cells to distal tubule and collecting duct cells.	Renal proximal tubule cells	Protein	Differential centrifugation Ultracentrifugation Immunoaffinity	Exosomes
305	Vesiclepedia_1085	25104112	Homo sapiens	Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy.	Plasma	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Exosomes
306	Vesiclepedia_994	24434149	Homo sapiens	In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome.	Ovarian cancer cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
307	Vesiclepedia_333	20976003	Homo sapiens	Selective release of microRNA species from normal and malignant mammary epithelial cells	Breast cancer cells	Protein miRNA	Differential centrifugation Filtration	Exosomes
308	Vesiclepedia_240	10233897	Homo sapiens	Elevated levels of circulating procoagulant microparticles in patients with paroxysmal nocturnal hemoglobinuria and aplastic anemia	Platelets	Protein Lipids	Differential centrifugation FACS	Microparticles
309	Vesiclepedia_405	19650833	Homo sapiens	Human liver stem cell-derived microvesicles accelerate hepatic regeneration in hepatectomized rats.	Hepatocytes	mRNA	-	Microvesicles
310	Vesiclepedia_167	21859146	Homo sapiens	Identification of a conserved glycan signature for microvesicles	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Microvesicles
311	Vesiclepedia_197	21616097	Homo sapiens	Release of podocalyxin into the extracellular space. Role of metalloproteinases	Testicular cancer cells	Protein	Differential centrifugation	Microvesicles
312	Vesiclepedia_290	12196479	Homo sapiens	Type 1 and type 2 diabetic patients display different patterns of cellular microparticles	Plasma	Protein Lipids	Differential centrifugation FACS	Microparticles
313	Vesiclepedia_272	8896411	Homo sapiens	High shear stress can initiate both platelet aggregation and shedding of procoagulant containing microparticles	Platelets	Protein Lipids	Differential centrifugation FACS	Microparticles
314	Vesiclepedia_112	21601258	Homo sapiens	Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage.	Serum	Protein miRNA	Differential centrifugation Sucrose density gradient	Exosomes
315	Vesiclepedia_796	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Embryonic kidney cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
316	Vesiclepedia_336	20976003	Homo sapiens	Selective release of microRNA species from normal and malignant mammary epithelial cells	Breast cancer cells	Protein miRNA	Differential centrifugation Filtration	Exosomes
317	Vesiclepedia_265	18425114	Homo sapiens	Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells	Endothelial cells	Protein	Differential centrifugation Ultracentrifugation	Microvesicles
318	Vesiclepedia_1017	22711894	Homo sapiens	Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages.	Macrophages	Protein Lipids	Differential centrifugation Filtration Ultracentrifugation	Exosomes
319	Vesiclepedia_289	12196479	Homo sapiens	Type 1 and type 2 diabetic patients display different patterns of cellular microparticles	Plasma	Protein Lipids	Differential centrifugation FACS	Microparticles
320	Vesiclepedia_418	21049385	Homo sapiens	The plasma microparticle proteome.	Plasma	Protein	-	Microparticles
321	Vesiclepedia_37	10878338	Homo sapiens	Direct immunosuppressive effects of EBV-encoded latent membrane protein 1.	B cells	Protein	Differential centrifugation	Exosomes
322	Vesiclepedia_518	23585443	Homo sapiens	Proteome profiling of exosomes derived from human primary and metastatic colorectal cells reveal differential expression of key metastatic factors and signal transduction components.	Colorectal cancer cells	Protein	-	Exosomes/Membrane vesicles
323	Vesiclepedia_575	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Breast cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
324	Vesiclepedia_58	17700640	Homo sapiens	CD24 is a marker of exosomes secreted into urine and amniotic fluid.	Amniotic fluid	Protein	Differential centrifugation Sucrose density gradient	Exosomes
325	Vesiclepedia_11	12519789	Homo sapiens	Proteomic and biochemical analyses of human B cell-derived exosomes. Potential implications for their function and multivesicular body formation.	B cells	Protein Lipids	Differential centrifugation Sucrose density gradient	Exosomes
326	Vesiclepedia_42	15908444	Homo sapiens	Exosomal-like vesicles are present in human blood plasma.	Bone marrow cells	Protein	Differential centrifugation Filtration Sucrose density gradient	Exosomes
327	Vesiclepedia_585	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Brain cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
328	Vesiclepedia_118	21362503	Homo sapiens	Protein profile of exosomes from trabecular meshwork cells.	Tabecular meshwork cells	Protein	Differential centrifugation Sucrose density gradient	Exosomes
329	Vesiclepedia_181	20668554	Homo sapiens	Microvesicles derived from adult human bone marrow and tissue specific mesenchymal stem cells shuttle selected pattern of miRNAs	Mesenchymal stem cells	Protein miRNA	Differential centrifugation Ultracentrifugation	Microvesicles
330	Vesiclepedia_205	19011622	Homo sapiens	Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers	Serum	mRNA miRNA	Differential centrifugation Ultracentrifugation Filtration	Microvesicles
331	Vesiclepedia_411	20124223	Homo sapiens	Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.	Squamous carcinoma cells	Protein	-	Exosomes
332	Vesiclepedia_884	29955024	Homo sapiens	Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells	Myeloid leukemia cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
333	Vesiclepedia_506	23465879	Homo sapiens	Lipidomic analysis of human placental Syncytiotrophoblast microvesicles in adverse pregnancy outcomes.	Placenta	Lipids	-	Microvesicles
334	Vesiclepedia_431	21595033	Homo sapiens	Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.	Urine	Protein	-	Exosomes
335	Vesiclepedia_538	23844026	Homo sapiens	Characterization of human thymic exosomes.	Thymus	Protein	-	Exosomes
336	Vesiclepedia_804	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
337	Vesiclepedia_107	21763319	Homo sapiens	Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells.	Pancreatic adenocarcinoma cells	Protein	Differential centrifugation Filtration Ultrafiltration Ultracentrifugation	Exosomes
338	Vesiclepedia_318	19483673	Homo sapiens	Y-box protein-1 is actively secreted through a non-classical pathway and acts as an extracellular mitogen	Monocytes	Protein	Differential centrifugation Filtration	Microvesicles
339	Vesiclepedia_68	19619303	Homo sapiens	Claudin-containing exosomes in the peripheral circulation of women with ovarian cancer.	Plasma	Protein	Differential centrifugation	Exosomes
340	Vesiclepedia_210	21368175	Homo sapiens	Cancer cell-derived microvesicles induce transformation by transferring tissue transglutaminase and fibronectin to recipient cells	Breast cancer cells	Protein	Differential centrifugation Filtration	Microvesicles
341	Vesiclepedia_155	21939504	Homo sapiens	Microvesicles secreted by macrophages shuttle invasion-potentiating microRNAs into breast cancer cells	Macrophages	miRNA	Differential centrifugation Filtration Ultracentrifugation	Microvesicles
342	Vesiclepedia_571	26858453	Homo sapiens	Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes	Dendritic cells	Protein	Differential centrifugation Ultracentrifugation Immunobeads (CD63 FT)	Extracellular vesicles
343	Vesiclepedia_632	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Ovarian cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
344	Vesiclepedia_199	21609964	Homo sapiens	Characterization of extracellular circulating microRNA	Plasma	Protein	Differential centrifugation Filtration	Exosomes
345	Vesiclepedia_886	25102470	Homo sapiens	Examination of the specificity of tumor cell derived exosomes with tumor cells in vitro	Breast cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
346	Vesiclepedia_283	19234131	Homo sapiens	Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR	Colorectal cancer cells	Protein	Differential centrifugation	Microvesicles
347	Vesiclepedia_519	23585444	Homo sapiens	Identification and characterization of proteins isolated from microvesicles derived from human lung cancer pleural effusions.	Malignant pleural effusions	Protein	-	Exosomes/Microvesicles/Ectosomes/Microparticles
348	Vesiclepedia_728	25359493	Homo sapiens	Proteomic signatures of extracellular vesicles secreted by nonmineralizing and mineralizing human osteoblasts and stimulation of tumor cell growth.	Osteoblasts	Protein	Differential centrifugation Ultracentrifugation	Matrix vesicles
349	Vesiclepedia_1010	23185418	Homo sapiens	Improved flow cytometric assessment reveals distinct microvesicle (cell-derived microparticle) signatures in joint diseases.	Synovial fluid	Protein	Filtration Ultracentrifugation	Microvesicles
350	Vesiclepedia_65	19415654	Homo sapiens	Proteomics of MUC1-containing lipid rafts from plasma membranes and exosomes of human breast carcinoma cells MCF-7.	Breast cancer cells	Protein	Differential centrifugation Sucrose density gradient	Exosomes
351	Vesiclepedia_876	29955024	Homo sapiens	Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells	Embryonic kidney cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
352	Vesiclepedia_1025	22327366	Homo sapiens	Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs.	Vascular endothelial cells	Protein miRNA	Differential centrifugation Ultracentrifugation	Extracellular vesicles
353	Vesiclepedia_444	22418980	Homo sapiens	A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.	Urine	Protein	-	Exosomes
354	Vesiclepedia_669	29953960	Homo sapiens	Exosomes derived from calcium oxalate-exposed macrophages enhance IL-8 production from renal cells, neutrophil migration and crystal invasion through extracellular matrix.	Macrophages	Protein	Microfiltration Differential centrifugation Ultracentrifugation	Exosomes
355	Vesiclepedia_668	29956871	Homo sapiens	Expression analysis of extracellular microRNA in bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis	Bronchoalveolar lavage fluid	miRNA	Differential centrifugation Ultracentrifugation Filtration	Microvesicles
356	Vesiclepedia_157	21630462	Homo sapiens	Proteomic analysis of microvesicles derived from human colorectal cancer ascites	Ascites	Protein	Differential centrifugation Sucrose density gradient OptiPrep density gradient	Microvesicles
357	Vesiclepedia_389	18819103	Homo sapiens	Structural heterogeneity and protein composition of exosome-like vesicles (prostasomes) in human semen.	Seminal fluid	Protein	-	Exosomes/Prostasomes
358	Vesiclepedia_223	10393703	Homo sapiens	In vitro generation of endothelial microparticles and possible prothrombotic activity in patients with lupus anticoagulant	Endothelial cells	Protein	Differential centrifugation Ultracentrifugation	Microparticles
359	Vesiclepedia_64	18520029	Homo sapiens	Exosome-like vesicles with dipeptidyl peptidase IV in human saliva.	Saliva	Protein	Filtration Diafiltration Gel filtration	Exosomes
360	Vesiclepedia_670	29953960	Homo sapiens	Exosomes derived from calcium oxalate-exposed macrophages enhance IL-8 production from renal cells, neutrophil migration and crystal invasion through extracellular matrix.	Macrophages	Protein	Microfiltration Differential centrifugation Ultracentrifugation	Exosomes
361	Vesiclepedia_170	21859146	Homo sapiens	Identification of a conserved glycan signature for microvesicles	Colorectal cancer cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Microvesicles
362	Vesiclepedia_1064	30006486	Homo sapiens	The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells.	Astrocytoma cells	Protein	Filtration Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
363	Vesiclepedia_976	22808001	Homo sapiens	Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment.	Serum	Protein	Filtration ExoQuick	Exosomes
364	Vesiclepedia_175	19002258	Homo sapiens	Detection of microRNA Expression in Human Peripheral Blood Microvesicles	Plasma	miRNA	Differential centrifugation	Microvesicles
365	Vesiclepedia_219	10694520	Homo sapiens	Elevated levels of shed membrane microparticles with procoagulant potential in the peripheral circulating blood of patients with acute coronary syndromes	Plasma	Protein	Immunoaffinity [Annexin-V]	Microparticles
366	Vesiclepedia_957	27601599	Homo sapiens	Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components.	Breast milk	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
367	Vesiclepedia_1066	29963299	Homo sapiens	Enrichment of extracellular vesicles from human synovial fluid using size exclusion chromatography.	Synovial fluid	Protein	Size exclusion chromatography	Extracellular vesicles
368	Vesiclepedia_1200	27780738	Homo sapiens	Next-generation sequencing-based small RNA profiling of cerebrospinal fluid exosomes.	Cerebrospinal fluid	miRNA	Differential centrifugation Ultracentrifugation	Exosomes
369	Vesiclepedia_1133	23861904	Homo sapiens	Exosomal signaling during hypoxia mediates microvascular endothelial cell migration and vasculogenesis.	Placental mesenchymal stem cells	Protein	Differential centrifugation Ultracentrifugation Ultrafiltration Density gradient centrifugation	Exosomes
370	Vesiclepedia_695	28842968	Homo sapiens	Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles.	Colorectal cancer cells	Protein	Differential centrifugation Ultracentrifugation	Microvesicles
371	Vesiclepedia_44	19028452	Homo sapiens	Proteomic profiling of human plasma exosomes identifies PPARgamma as an exosome-associated protein.	Plasma	Protein	Filtration Size exclusion chromatography Sucrose density gradient	Exosomes
372	Vesiclepedia_229	2942561	Homo sapiens	Platelet surface glycoproteins. Studies on resting and activated platelets and platelet membrane microparticles in normal subjects, and observations in patients during adult respiratory distress syndrome and cardiac surgery	Plasma	Protein	Differential centrifugation	Microparticles
373	Vesiclepedia_964	25844599	Homo sapiens	Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
374	Vesiclepedia_545	23983189	Homo sapiens	Characterization of Multiple Myeloma Vesicles by Label-Free Relative Quantitation.	B cells	Protein	-	Exosomes/Extracellular vesicles/Microvesicles
375	Vesiclepedia_357	24352158	Homo sapiens	Characterization and deep sequencing analysis of exosomal miRNA in human urine	Urine	miRNA	Differential centrifugation Norgen Biotek Exosome kit	Exosomes
376	Vesiclepedia_1116	24391718	Homo sapiens	Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.	Prostate epithelial cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
377	Vesiclepedia_340	20615901	Homo sapiens	Export of microRNAs and microRNA-protective protein by mammalian cells	Lung cancer cells	miRNA	Differential centrifugation	Exosomes
378	Vesiclepedia_847	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
379	Vesiclepedia_925	25483805	Homo sapiens	Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties	Embryonic kidney cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
380	Vesiclepedia_1262	24371517	Homo sapiens	Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients.	Urine	Protein	Differential centrifugation Ultracentrifugation	Exosomes
381	Vesiclepedia_50	14582906	Homo sapiens	Exosomes with major histocompatibility complex class II and co-stimulatory molecules are present in human BAL fluid.	Dendritic cells	Protein	Differential centrifugation Immunobeads (EpCAM)	Exosomes
382	Vesiclepedia_1114	24391718	Homo sapiens	Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
383	Vesiclepedia_443	22329422	Homo sapiens	Quantitative proteome profiling of normal human circulating microparticles.	Plasma	Protein	-	Microparticles
384	Vesiclepedia_513	23533145	Homo sapiens	In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.	Urine	Protein	-	Exosomes/Microvesicles
385	Vesiclepedia_953	27601599	Homo sapiens	Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components.	Breast milk	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
386	Vesiclepedia_1230	25503107	Homo sapiens	Tumor-derived microvesicles mediate human breast cancer invasion through differentially glycosylated EMMPRIN.	Breast cancer cells	Protein	Ultracentrifugation Filtration Density gradient centrifugation	Microvesicles
387	Vesiclepedia_1083	25104112	Homo sapiens	Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy.	Plasma	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Exosomes
388	Vesiclepedia_590	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Colorectal cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
389	Vesiclepedia_293	10415024	Homo sapiens	Activated human T cells release bioactive Fas ligand and APO2 ligand in microvesicles	T cells	Protein	Differential centrifugation Ultracentrifugation FACS	Microvesicles
390	Vesiclepedia_620	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Melanoma cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
391	Vesiclepedia_892	24946052	Homo sapiens	Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment	Lung cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
392	Vesiclepedia_629	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Ovarian cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
393	Vesiclepedia_34	19190083	Homo sapiens	Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense.	Tracheobronchial cells	Protein mRNA	Differential centrifugation Filtration Sucrose density gradient	Exosomes
394	Vesiclepedia_85	20949044	Homo sapiens	Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line	Lung cancer cells	miRNA	Differential centrifugation Filtration Ultracentrifugation	Exosomes
395	Vesiclepedia_1181	28684402	Homo sapiens	BRAFV600 inhibition alters the microRNA cargo in the vesicular secretome of malignant melanoma cells	Melanoma cells	miRNA	Differential centrifugation Filtration Ultracentrifugation	Extracellular vesicles
396	Vesiclepedia_355	24115447	Homo sapiens	Comparative proteomics evaluation of plasma exosome isolation techniques and assessment of the stability of exosomes in normal human blood plasma	Plasma	Protein	Differential centrifugation Filtration Ultracentrifugation Immunoaffinity (EpCAM)	Exosomes
397	Vesiclepedia_540	23886663	Homo sapiens	LRRK2 Secretion in Exosomes is Regulated by 14-3-3.	Urine	Protein	-	Exosomes/Microvesicles
398	Vesiclepedia_334	20976003	Homo sapiens	Selective release of microRNA species from normal and malignant mammary epithelial cells	Breast cancer cells	Protein miRNA	Differential centrifugation Filtration	Exosomes
399	Vesiclepedia_1061	30006486	Homo sapiens	The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells.	Astrocytoma cells	Protein	Filtration Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
400	Vesiclepedia_1202	27780738	Homo sapiens	Next-generation sequencing-based small RNA profiling of cerebrospinal fluid exosomes.	Cerebrospinal fluid	miRNA	Differential centrifugation Ultracentrifugation	Exosomes
401	Vesiclepedia_308	16342139	Homo sapiens	Proteomic analysis of malignant lymphocyte membrane microparticles using double ionization coverage optimization	B cells	Protein	Differential centrifugation	Microparticles
402	Vesiclepedia_628	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Ovarian cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
403	Vesiclepedia_66	19199708	Homo sapiens	Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).	Saliva	Protein	Differential centrifugation	Exosomes
404	Vesiclepedia_1142	23454749	Homo sapiens	BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression.	Bone marrow mesenchymal stromal cells	Protein	Differential centrifugation Ultracentrifugation Filtration ExoQuick	Exosomes
405	Vesiclepedia_664	29956871	Homo sapiens	Expression analysis of extracellular microRNA in bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis	Bronchoalveolar lavage fluid	Protein	Differential centrifugation Ultracentrifugation Filtration	Microvesicles
406	Vesiclepedia_662	29956871	Homo sapiens	Expression analysis of extracellular microRNA in bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis	Bronchoalveolar lavage fluid	Protein	Differential centrifugation Ultracentrifugation Filtration	Microvesicles
407	Vesiclepedia_681	29148239	Homo sapiens	Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants.	Umblical cord mesenchymal stem cells	Protein	Differential centrifugation Ultracentrifugation Sonication Filtration	Microvesicles
408	Vesiclepedia_572	26858453	Homo sapiens	Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes	Dendritic cells	Protein	Differential centrifugation Ultracentrifugation Immunobeads (CD81 PD)	Extracellular vesicles
409	Vesiclepedia_1042	27770278	Homo sapiens	Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease.	Glioblastoma cells	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Extracellular vesicles
410	Vesiclepedia_651	29188495	Homo sapiens	Protein Biomarkers and Neuroproteomics Characterization of Microvesicles/Exosomes from Human Cerebrospinal Fluid Following Traumatic Brain Injury.	Cerebrospinal fluid	Protein	Differential centrifugation Ultracentrifugation Sonication Filtration	Extracellular vesicles
411	Vesiclepedia_284	12796750	Homo sapiens	High levels of circulating endothelial microparticles in patients with acute coronary syndromes	Plasma	Protein	Differential centrifugation FACS	Microparticles
412	Vesiclepedia_688	28170197	Homo sapiens	Enhanced Cardioprotection by Human Endometrium Mesenchymal Stem Cells Driven by Exosomal MicroRNA-21	Endometrium-derived mesenchymal stem cells	miRNA	Differential centrifugation Filtration Ultracentrifugation	Exosomes
413	Vesiclepedia_218	10694520	Homo sapiens	Elevated levels of shed membrane microparticles with procoagulant potential in the peripheral circulating blood of patients with acute coronary syndromes	Plasma	Protein	Immunoaffinity [Annexin-V]	Microparticles
414	Vesiclepedia_75	19381331	Homo sapiens	High levels of exosomes expressing CD63 and caveolin-1 in plasma of melanoma patients.	Plasma	Protein	Differential centrifugation	Exosomes
415	Vesiclepedia_498	23376485	Homo sapiens	Proteomic analysis of podocyte exosome-enriched fraction from normal human urine.	Urine	Protein	-	Exosomes/Membrane vesicles
416	Vesiclepedia_330	20304794	Homo sapiens	Functional delivery of viral miRNAs via exosomes	B cells	miRNA	Differential centrifugation	Exosomes
417	Vesiclepedia_858	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer	Plasma	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
418	Vesiclepedia_115	21505438	Homo sapiens	Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells.	T cells	Protein miRNA	Differential centrifugation Filtration Ultracentrifugation	Exosomes
419	Vesiclepedia_250	9396452	Homo sapiens	Cell-derived microparticles generated in patients during cardiopulmonary bypass are highly procoagulant	Plasma	Protein Lipids	Differential centrifugation	Microparticles
420	Vesiclepedia_536	23818640	Homo sapiens	Modulation of B-cell exosome proteins by gamma herpesvirus infection.	B cells	Protein	-	Exosomes/Microvesicles/Oncosomes/Microparticles
421	Vesiclepedia_387	18563738	Homo sapiens	Comparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles.	Endothelial cells	Protein	-	Microparticles
422	Vesiclepedia_440	22251860	Homo sapiens	RNA expression patterns in serum microvesicles from patients with glioblastoma multiforme and controls.	Serum	mRNA	-	Exosomes/Microvesicles
423	Vesiclepedia_396	19413345	Homo sapiens	Proteomic analysis of malignant B-cell derived microparticles reveals CD148 as a potentially useful antigenic biomarker for mantle cell lymphoma diagnosis.	B cells	Protein	-	Microparticles
424	Vesiclepedia_1264	24371517	Homo sapiens	Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients.	Urine	Protein	Differential centrifugation Ultracentrifugation	Exosomes
425	Vesiclepedia_1041	27770278	Homo sapiens	Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease.	Glioblastoma cells	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Extracellular vesicles
426	Vesiclepedia_899	26100252	Homo sapiens	Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts	Chronic lymphocytic leukemia cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
427	Vesiclepedia_316	18472965	Homo sapiens	Cathepsin B mediates the pH-dependent proinvasive activity of tumor-shed microvesicles	Ovarian cancer cells	Protein	Differential centrifugation	Microvesicles
428	Vesiclepedia_32	18452139	Homo sapiens	Primary human keratinocytes externalize stratifin protein via exosomes.	Keratinocytes	Protein	Differential centrifugation Sucrose density gradient Diafiltration	Exosomes
429	Vesiclepedia_1248	24939845	Homo sapiens	Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein.	Leukemia cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
430	Vesiclepedia_376	18346024	Homo sapiens	The proteome of red cell membranes and vesicles during storage in blood bank conditions.	Red blood cells	Protein	-	Microvesicles/Nanovesicles
431	Vesiclepedia_119	21362503	Homo sapiens	Protein profile of exosomes from trabecular meshwork cells.	Urine	Protein	Differential centrifugation Sucrose density gradient	Exosomes
432	Vesiclepedia_52	14975938	Homo sapiens	Proteomic analysis of exosomes isolated from human malignant pleural effusions.	Malignant pleural effusions	Protein	Differential centrifugation Sucrose density gradient	Exosomes
433	Vesiclepedia_1209	29127410	Homo sapiens	Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies.	Bronchial epithelial cells	Protein	Ultrafiltration Size exclusion chromatography	Extracellular vesicles
434	Vesiclepedia_1201	27780738	Homo sapiens	Next-generation sequencing-based small RNA profiling of cerebrospinal fluid exosomes.	Cerebrospinal fluid	miRNA	Differential centrifugation Ultracentrifugation	Exosomes
435	Vesiclepedia_1136	23861904	Homo sapiens	Exosomal signaling during hypoxia mediates microvascular endothelial cell migration and vasculogenesis.	Placental mesenchymal stem cells	Protein	Differential centrifugation Ultracentrifugation Ultrafiltration Density gradient centrifugation	Exosomes
436	Vesiclepedia_1076	25104112	Homo sapiens	Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy.	Plasma	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Exosomes
437	Vesiclepedia_1082	25104112	Homo sapiens	Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy.	Plasma	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Exosomes
438	Vesiclepedia_401	19548909	Homo sapiens	Differential stimulation of monocytic cells results in distinct populations of microparticles.	Monocytes	Protein	-	Microparticles
439	Vesiclepedia_1119	24391718	Homo sapiens	Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
440	Vesiclepedia_896	26100252	Homo sapiens	Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts	Chronic lymphocytic leukemia cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
441	Vesiclepedia_705	28811610	Homo sapiens	Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA.	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Microvesicles/Apoptotic bodies
442	Vesiclepedia_580	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Brain cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
443	Vesiclepedia_594	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Kidney cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
444	Vesiclepedia_380	18346024	Homo sapiens	The proteome of red cell membranes and vesicles during storage in blood bank conditions.	Red blood cells	Protein	-	Microvesicles/Nanovesicles
445	Vesiclepedia_116	21505438	Homo sapiens	Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells.	B cells	Protein miRNA	Differential centrifugation Filtration Ultracentrifugation	Exosomes
446	Vesiclepedia_21	19837982	Homo sapiens	Proteomic and bioinformatic analysis of immunoaffinity-purified exosomes derived from the human colon tumor cell line LIM1215.	Colorectal cancer cells	Protein	Filtration Ultracentrifugation Sucrose density gradient	Exosomes
447	Vesiclepedia_113	21557262	Homo sapiens	Proteomic identification of exosomal LRG1: A potential urinary biomarker for detecting NSCLC.	Urine	Protein	Differential centrifugation Ultracentrifugation	Exosomes
448	Vesiclepedia_1074	25104112	Homo sapiens	Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy.	Plasma	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Exosomes
449	Vesiclepedia_801	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Embryonic kidney cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
450	Vesiclepedia_805	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
451	Vesiclepedia_600	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Kidney cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
452	Vesiclepedia_509	23521563	Homo sapiens	First identification of Ewing's sarcoma-derived extracellular vesicles and exploration of their biological and potential diagnostic implications.	Ewing's sarcoma cells	mRNA	-	Exosomes/Extracellular vesicles
453	Vesiclepedia_299	12796750	Homo sapiens	High levels of circulating endothelial microparticles in patients with acute coronary syndromes	Plasma	Protein	Differential centrifugation FACS	Microparticles
454	Vesiclepedia_800	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Embryonic kidney cells	Protein	Differential centrifugation	Microvesicles
455	Vesiclepedia_1137	23861904	Homo sapiens	Exosomal signaling during hypoxia mediates microvascular endothelial cell migration and vasculogenesis.	Placental mesenchymal stem cells	Protein	Differential centrifugation Ultracentrifugation Ultrafiltration Density gradient centrifugation	Exosomes
456	Vesiclepedia_993	24434149	Homo sapiens	In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome.	Ovarian cancer cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
457	Vesiclepedia_314	15499615	Homo sapiens	Microvesicles derived from activated platelets induce metastasis and angiogenesis in lung cancer	Lung cancer cells	Protein	Differential centrifugation FACS	Microvesicles
458	Vesiclepedia_627	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Ovarian cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
459	Vesiclepedia_4	11487543	Homo sapiens	Intestinal epithelial cells secrete exosome-like vesicles.	Epithelial cells	Protein	Differential centrifugation Sucrose density gradient	Exosomes
460	Vesiclepedia_598	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Kidney cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
461	Vesiclepedia_28	19109410	Homo sapiens	Proteomic and immunologic analyses of brain tumor exosomes.	Glioma cells	Protein	Differential centrifugation Sucrose density gradient	Exosomes
462	Vesiclepedia_1140	23454749	Homo sapiens	BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression.	Bone marrow mesenchymal stromal cells	Protein	Differential centrifugation Ultracentrifugation Filtration ExoQuick	Exosomes
463	Vesiclepedia_520	23601281	Homo sapiens	Proteomic characterization of human platelet-derived microparticles.	Platelets	Protein	-	Microparticles
464	Vesiclepedia_450	22451062	Homo sapiens	A hyphenated microLC-Q-TOF-MS platform for exosomal lipidomics investigations: application to RCC urinary exosomes.	Urine	Lipids	-	Exosomes
465	Vesiclepedia_658	28753793	Homo sapiens	MicroRNAs in Serum Exosomes as Potential Biomarkers in Clear-cell Renal Cell Carcinoma.	Serum	miRNA	Total Exosome Isolation Kit Differential centrifugation Ultracentrifugation Immunobeads (EpCAM)	Exosomes
466	Vesiclepedia_143	22723089	Homo sapiens	Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes.	Prostate cancer cells	Protein	Sucrose density gradient	Exosomes
467	Vesiclepedia_843	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
468	Vesiclepedia_258	9126269	Homo sapiens	Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations	Leukemia cells	Protein	Differential centrifugation Sucrose density gradient	Microvesicles
469	Vesiclepedia_1036	29887978	Homo sapiens	Evaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing.	Serum	Protein miRNA	Exo-spin	Extracellular vesicles
470	Vesiclepedia_563	26858453	Homo sapiens	Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes	Dendritic cells	Protein	Differential centrifugation Ultracentrifugation OptiPrep density gradient	Microvesicles
471	Vesiclepedia_1211	29127410	Homo sapiens	Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies.	Bronchial epithelial cells	Protein	Ultrafiltration Size exclusion chromatography	Extracellular vesicles
472	Vesiclepedia_177	19567368	Homo sapiens	Proteomics characterization of cell membrane blebs in human retinal pigment epithelium cells	Epithelial cells	Protein	Differential centrifugation	Membrane blebs
473	Vesiclepedia_1272	24058411	Homo sapiens	Osteoprotegerin in exosome-like vesicles from human cultured tubular cells and urine.	Urine	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
474	Vesiclepedia_451	22451062	Homo sapiens	A hyphenated microLC-Q-TOF-MS platform for exosomal lipidomics investigations: application to RCC urinary exosomes.	Urine	Lipids	-	Exosomes
475	Vesiclepedia_889	24946052	Homo sapiens	Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment	Lung cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
476	Vesiclepedia_977	22808001	Homo sapiens	Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment.	Serum	Protein	Filtration ExoQuick	Exosomes
477	Vesiclepedia_1144	23454749	Homo sapiens	BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression.	Bone marrow mesenchymal stromal cells	Protein	Differential centrifugation Ultracentrifugation Filtration ExoQuick	Exosomes
478	Vesiclepedia_251	9396452	Homo sapiens	Cell-derived microparticles generated in patients during cardiopulmonary bypass are highly procoagulant	Plasma	Protein Lipids	Differential centrifugation	Microparticles
479	Vesiclepedia_995	24434149	Homo sapiens	In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome.	Ovarian cancer cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
480	Vesiclepedia_379	18346024	Homo sapiens	The proteome of red cell membranes and vesicles during storage in blood bank conditions.	Red blood cells	Protein	-	Microvesicles/Nanovesicles
481	Vesiclepedia_567	26858453	Homo sapiens	Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes	Dendritic cells	Protein	Differential centrifugation Ultracentrifugation Immunobeads (Igg1 FT)	Extracellular vesicles
482	Vesiclepedia_1225	26154623	Homo sapiens	Size-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals	Plasma	Protein	Exo-spin	Extracellular vesicles
483	Vesiclepedia_132	19188015	Homo sapiens	Systemic presence and tumor-growth promoting effect of ovarian carcinoma released exosomes	Ovarian cancer cells	Protein Lipids	Differential centrifugation Sucrose density gradient	Exosomes
484	Vesiclepedia_849	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
485	Vesiclepedia_136	22723089	Homo sapiens	Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes.	Prostate cancer cells	Protein	Sucrose density gradient	Exosomes
486	Vesiclepedia_937	29207636	Homo sapiens	Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer.	Urine	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
487	Vesiclepedia_1240	25329303	Homo sapiens	Rapid isolation of extracellular vesicles from cell culture and biological fluids using a synthetic peptide with specific affinity for heat shock proteins.	Urine	Protein	Ultracentrifugation	Extracellular vesicles
488	Vesiclepedia_168	21859146	Homo sapiens	Identification of a conserved glycan signature for microvesicles	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Microvesicles
489	Vesiclepedia_475	23056502	Homo sapiens	Identifying mRNA, MicroRNA and Protein Profiles of Melanoma Exosomes.	Melanoma cells	mRNA	-	Exosomes
490	Vesiclepedia_268	12757771	Homo sapiens	Endothelial cells release phenotypically and quantitatively distinct microparticles in activation and apoptosis	Endothelial cells	Protein	Differential centrifugation FACS	Microparticles
491	Vesiclepedia_228	2942561	Homo sapiens	Platelet surface glycoproteins. Studies on resting and activated platelets and platelet membrane microparticles in normal subjects, and observations in patients during adult respiratory distress syndrome and cardiac surgery	Serum	Protein	Differential centrifugation	Microparticles
492	Vesiclepedia_146	22723089	Homo sapiens	Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes.	Prostate cancer cells	Protein	Sucrose density gradient	Exosomes
493	Vesiclepedia_457	22723089	Homo sapiens	Exosomes as Biomarker Enriched Microvesicles: Characterization of Exosomal Proteins derived from a Panel of Prostate Cell Lines with distinct AR phenotypes.	Prostate cancer cells	Lipids	-	Exosomes/Membrane vesicles/Microvesicles
494	Vesiclepedia_854	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
495	Vesiclepedia_542	23935504	Homo sapiens	A Novel Role for Pro-Coagulant Microvesicles in the Early Host Defense against Streptococcus pyogenes.	Peripheral blood mononucelar cells	Protein	-	Microvesicles
496	Vesiclepedia_319	20615901	Homo sapiens	Export of microRNAs and microRNA-protective protein by mammalian cells	Lung cancer cells	miRNA	Differential centrifugation	Microvesicles
497	Vesiclepedia_704	28811610	Homo sapiens	Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA.	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Microvesicles/Apoptotic bodies
498	Vesiclepedia_51	14975938	Homo sapiens	Proteomic analysis of exosomes isolated from human malignant pleural effusions.	Malignant pleural effusions	Protein	Differential centrifugation Sucrose density gradient	Exosomes
499	Vesiclepedia_12	15478216	Homo sapiens	Proteomic analysis of melanoma-derived exosomes by two-dimensional polyacrylamide gel electrophoresis and mass spectrometry.	Melanoma cells	Protein	Filtration Ultracentrifugation Sucrose density gradient	Exosomes
500	Vesiclepedia_1252	24939845	Homo sapiens	Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein.	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
501	Vesiclepedia_322	19951903	Homo sapiens	MicroRNA-29a regulates intestinal membrane permeability in patients with irritable bowel syndrome	Plasma	miRNA	Differential centrifugation Filtration	Microvesicles
502	Vesiclepedia_1104	24391718	Homo sapiens	Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.	Prostate epithelial cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
503	Vesiclepedia_1232	25475747	Homo sapiens	Identification of Biomarkers for PKD1 Using Urinary Exosomes	Urine	Protein	Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
504	Vesiclepedia_309	17536014	Homo sapiens	Endothelial progenitor cell derived microvesicles activate an angiogenic program in endothelial cells by a horizontal transfer of Mrna	Endothelial cells	Protein mRNA	Differential centrifugation Ultracentrifugation FACS	Microvesicles
505	Vesiclepedia_691	28170197	Homo sapiens	Enhanced Cardioprotection by Human Endometrium Mesenchymal Stem Cells Driven by Exosomal MicroRNA-21	Endometrium-derived mesenchymal stem cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
506	Vesiclepedia_1186	28326167	Homo sapiens	Residual urinary extracellular vesicles in ultracentrifugation supernatants after hydrostatic filtration dialysis enrichment.	Urine	Protein	Hydrostatic filtration dialysis Differential centrifugation Ultracentrifugation	Extracellular vesicles
507	Vesiclepedia_842	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
508	Vesiclepedia_1223	26154623	Homo sapiens	Size-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals	Plasma	Protein	Exo-spin	Extracellular vesicles
509	Vesiclepedia_327	20428099	Homo sapiens	Nucleic acids within urinary exosomes/microvesicles are potential biomarkers for renal disease	Urine	mRNA	Differential centrifugation Ultracentrifugation	Exosomes
510	Vesiclepedia_1268	24218614	Homo sapiens	Unexpected gain of function for the scaffolding protein plectin due to mislocalization in pancreatic cancer.	Pancreatic adenocarcinoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
511	Vesiclepedia_573	26858453	Homo sapiens	Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes	Dendritic cells	Protein	Differential centrifugation Ultracentrifugation Immunobeads (CD81 FT)	Extracellular vesicles
512	Vesiclepedia_605	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Leukemia cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
513	Vesiclepedia_202	21601655	Homo sapiens	Sizing and phenotyping of cellular vesicles using Nanoparticle Tracking Analysis	Placenta	Protein	Differential centrifugation Ultracentrifugation	Microvesicles
514	Vesiclepedia_1024	22327366	Homo sapiens	Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs.	Vascular endothelial cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
515	Vesiclepedia_692	28170197	Homo sapiens	Enhanced Cardioprotection by Human Endometrium Mesenchymal Stem Cells Driven by Exosomal MicroRNA-21	Adipose-derived mesenchymal stem cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
516	Vesiclepedia_1249	24939845	Homo sapiens	Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein.	Leukemia cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
517	Vesiclepedia_1106	24391718	Homo sapiens	Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.	Prostate epithelial cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
518	Vesiclepedia_958	26196085	Homo sapiens	Identification of prostate cancer biomarkers in urinary exosomes.	Urine	Protein	Differential centrifugation Ultracentrifugation Filtration	Exosomes
519	Vesiclepedia_1192	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
520	Vesiclepedia_1212	29127410	Homo sapiens	Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies.	Bronchial epithelial cells	Protein	Ultracentrifugation	Extracellular vesicles
521	Vesiclepedia_1096	24976626	Homo sapiens	Exosomal transfer from human renal proximal tubule cells to distal tubule and collecting duct cells.	Renal proximal tubule cells	Protein	Differential centrifugation Ultracentrifugation Immunoaffinity	Exosomes
522	Vesiclepedia_1178	29854963	Homo sapiens	Genome-wide Profiling of Urinary Extracellular Vesicle microRNAs Associated With Diabetic Nephropathy in Type 1 Diabetes.	Urine	miRNA	qEV size-exclusion column	Extracellular vesicles
523	Vesiclepedia_743	29988836	Homo sapiens	Ultrafiltration and size exclusion chromatography combined with asymmetrical-flow field-flow fractionation for the isolation and characterisation of extracellular vesicles from urine	Urine	Protein	Filtration Size exclusion chromatography	Extracellular vesicles
524	Vesiclepedia_1073	25104112	Homo sapiens	Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy.	Plasma	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Exosomes
525	Vesiclepedia_845	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
526	Vesiclepedia_307	16342139	Homo sapiens	Proteomic analysis of malignant lymphocyte membrane microparticles using double ionization coverage optimization	T cells	Protein	Differential centrifugation	Microparticles
527	Vesiclepedia_1189	28326167	Homo sapiens	Residual urinary extracellular vesicles in ultracentrifugation supernatants after hydrostatic filtration dialysis enrichment.	Urine	Protein	Hydrostatic filtration dialysis Differential centrifugation Ultracentrifugation	Extracellular vesicles
528	Vesiclepedia_618	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Melanoma cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
529	Vesiclepedia_680	29148239	Homo sapiens	Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants.	Umblical cord mesenchymal stem cells	Protein	Differential centrifugation Ultracentrifugation Sonication Filtration	Microvesicles
530	Vesiclepedia_687	29148239	Homo sapiens	Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants.	Umblical cord mesenchymal stem cells	Protein	Differential centrifugation Ultracentrifugation Sonication Filtration	Microvesicles
531	Vesiclepedia_1031	29887978	Homo sapiens	Evaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing.	Serum	Protein miRNA	exoEasy columns	Extracellular vesicles
532	Vesiclepedia_515	23539611	Homo sapiens	microRNA signature is altered in both human epididymis and seminal microvesicles following vasectomy.	Seminal fluid	miRNA	-	Microvesicles
533	Vesiclepedia_151	22075275	Homo sapiens	Methodology for isolation, identification and characterization of microvesicles in peripheral blood	Plasma	Protein	Differential centrifugation Filtration Ultracentrifugation	Microvesicles
534	Vesiclepedia_1094	25065644	Homo sapiens	Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells.	Duodenal cancer cells	Protein	Differential centrifugation Filtration Ultrafiltration	Exosomes
535	Vesiclepedia_956	27601599	Homo sapiens	Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components.	Breast milk	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
536	Vesiclepedia_718	26148937	Homo sapiens	Proteomics profiling of cholangiocarcinoma exosomes: A potential role of oncogenic protein transferring in cancer progression.	Cholangiocarcinoma cells	Protein	Differential centrifugation Ultracentrifugation Filtration	Exosomes
537	Vesiclepedia_1203	27780738	Homo sapiens	Next-generation sequencing-based small RNA profiling of cerebrospinal fluid exosomes.	Serum	miRNA	Differential centrifugation Ultracentrifugation	Exosomes
538	Vesiclepedia_541	23935504	Homo sapiens	A Novel Role for Pro-Coagulant Microvesicles in the Early Host Defense against Streptococcus pyogenes.	Peripheral blood mononucelar cells	Protein	-	Microvesicles
539	Vesiclepedia_1138	23707955	Homo sapiens	Prostasomes from four different species are able to produce extracellular adenosine triphosphate (ATP).	Seminal plasma	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Prostasomes
540	Vesiclepedia_235	10648405	Homo sapiens	Cellular origin and procoagulant properties of microparticles in meningococcal sepsis	Plasma	Protein	Differential centrifugation FACS	Microparticles
541	Vesiclepedia_1193	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
542	Vesiclepedia_715	28811610	Homo sapiens	Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA.	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Apoptotic bodies
543	Vesiclepedia_1122	24347249	Homo sapiens	Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation ExoQuick	Exosomes
544	Vesiclepedia_257	9126269	Homo sapiens	Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations	Leukemia cells	Protein	Differential centrifugation Sucrose density gradient	Microvesicles
545	Vesiclepedia_1191	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
546	Vesiclepedia_959	26196085	Homo sapiens	Identification of prostate cancer biomarkers in urinary exosomes.	Urine	Protein	Differential centrifugation Ultracentrifugation Filtration	Exosomes
547	Vesiclepedia_128	14965343	Homo sapiens	Mast cell- and dendritic cell-derived exosomes display a specific lipid composition and an unusual membrane organization	Dendritic cells	Lipids	Differential centrifugation Ultracentrifugation	Exosomes
548	Vesiclepedia_19	16302729	Homo sapiens	Purification, characterization and biological significance of tumor-derived exosomes.	Breast cancer cells	Protein	Differential centrifugation Sucrose density gradient Filtration Immunobeads(HER2)	Exosomes
549	Vesiclepedia_137	22723089	Homo sapiens	Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes.	Prostate cancer cells	Protein	Sucrose density gradient	Exosomes
550	Vesiclepedia_142	22723089	Homo sapiens	Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes.	Prostate cancer cells	Protein	Sucrose density gradient	Exosomes
551	Vesiclepedia_230	2294986	Homo sapiens	Direct detection of activated platelets and platelet-derived microparticles in humans	Plasma	Protein	FACS	Microparticles
552	Vesiclepedia_126	-	Homo sapiens	Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?	Mesenchymal stem cells	Protein	HPLC	Exosomes
553	Vesiclepedia_160	21630462	Homo sapiens	Proteomic analysis of microvesicles derived from human colorectal cancer ascites	Ascites	Protein	Differential centrifugation Sucrose density gradient OptiPrep density gradient	Microvesicles
554	Vesiclepedia_1070	29937354	Homo sapiens	Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors.	Glioblastoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
555	Vesiclepedia_900	26100252	Homo sapiens	Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts	Chronic lymphocytic leukemia cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
556	Vesiclepedia_797	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Embryonic kidney cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
557	Vesiclepedia_1224	26154623	Homo sapiens	Size-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals	Plasma	Protein	Exo-spin	Extracellular vesicles
558	Vesiclepedia_482	23161513	Homo sapiens	Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.	Colorectal cancer cells	Protein	-	Exosomes
559	Vesiclepedia_930	29207636	Homo sapiens	Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer.	Bladder cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
560	Vesiclepedia_262	12805058	Homo sapiens	Sickle blood contains tissue factor-positive microparticles derived from endothelial cells and monocytes	Plasma	Protein Lipids	Differential centrifugation Ultracentrifugation FACS	Microparticles
561	Vesiclepedia_216	21293856	Homo sapiens	Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC	Breast cancer cells	Protein	Differential centrifugation Filtration Ultrafiltration Ultracentrifugation Sucrose density gradient	Exosomes
562	Vesiclepedia_1287	20880880	Homo sapiens	Proinflammatory exosomes in bronchoalveolar lavage fluid of patients with sarcoidosis.	Bronchoalveolar lavage fluid	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
563	Vesiclepedia_124	21235781	Homo sapiens	Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages.	Breast milk	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
564	Vesiclepedia_1015	22711894	Homo sapiens	Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages.	Macrophages	Protein Lipids	Differential centrifugation Filtration Ultracentrifugation	Exosomes
565	Vesiclepedia_589	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Colorectal cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
566	Vesiclepedia_904	25053844	Homo sapiens	Activity-associated miRNA are packaged in Map1b-enriched exosomes released from depolarized neurons	Neuroblastoma cells	miRNA	Differential centrifugation Ultracentrifugation Filtration	Exosomes
567	Vesiclepedia_238	21293856	Homo sapiens	Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC	Ascites	Protein	Differential centrifugation Filtration Ultrafiltration Ultracentrifugation Sucrose density gradient	Exosomes
568	Vesiclepedia_1107	24391718	Homo sapiens	Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.	Prostate epithelial cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
569	Vesiclepedia_1087	25065644	Homo sapiens	Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells.	Duodenal cancer cells	Protein	Differential centrifugation Filtration Ultrafiltration	Exosomes
570	Vesiclepedia_712	28811610	Homo sapiens	Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA.	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Apoptotic bodies
571	Vesiclepedia_329	20304794	Homo sapiens	Functional delivery of viral miRNAs via exosomes	B cells	miRNA	Differential centrifugation	Exosomes
572	Vesiclepedia_529	23786572	Homo sapiens	Phospholipidomics of Human Blood Microparticles.	Plasma	Lipids	-	Microparticles
573	Vesiclepedia_672	29953960	Homo sapiens	Exosomes derived from calcium oxalate-exposed macrophages enhance IL-8 production from renal cells, neutrophil migration and crystal invasion through extracellular matrix.	Macrophages	Protein	Microfiltration Differential centrifugation Ultracentrifugation	Exosomes
574	Vesiclepedia_140	22723089	Homo sapiens	Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes.	Prostate cancer cells	Protein	Sucrose density gradient	Exosomes
575	Vesiclepedia_254	9126269	Homo sapiens	Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations	Leukemia cells	Protein	Differential centrifugation Sucrose density gradient	Microvesicles
576	Vesiclepedia_263	12805058	Homo sapiens	Sickle blood contains tissue factor-positive microparticles derived from endothelial cells and monocytes	Plasma	Protein	Differential centrifugation Ultracentrifugation FACS	Microparticles
577	Vesiclepedia_924	25483805	Homo sapiens	Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties	Embryonic kidney cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
578	Vesiclepedia_883	29955024	Homo sapiens	Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells	Myeloid leukemia cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
579	Vesiclepedia_45	18589210	Homo sapiens	MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer.	Serum	Protein miRNA	Ultracentrifugation Immunobeads (EpCAM)	Exosomes
580	Vesiclepedia_1115	24391718	Homo sapiens	Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
581	Vesiclepedia_731	25359493	Homo sapiens	Proteomic signatures of extracellular vesicles secreted by nonmineralizing and mineralizing human osteoblasts and stimulation of tumor cell growth.	Osteoblasts	Protein	Differential centrifugation Ultracentrifugation	Matrix vesicles
582	Vesiclepedia_579	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Breast cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
583	Vesiclepedia_103	21763319	Homo sapiens	Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells.	Pancreatic adenocarcinoma cells	Protein	Differential centrifugation Filtration Ultrafiltration Ultracentrifugation	Exosomes
584	Vesiclepedia_963	25844599	Homo sapiens	Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
585	Vesiclepedia_613	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Lung cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
586	Vesiclepedia_556	24069378	Homo sapiens	Proteome profiling of neuroblastoma-derived exosomes reveal the expression of proteins potentially involved in tumor progression.	Neuroblastoma cells	Protein	-	Exosomes/Membrane vesicles
587	Vesiclepedia_29	19109410	Homo sapiens	Proteomic and immunologic analyses of brain tumor exosomes.	Serum	Protein	Differential centrifugation Sucrose density gradient	Exosomes
588	Vesiclepedia_315	15499615	Homo sapiens	Microvesicles derived from activated platelets induce metastasis and angiogenesis in lung cancer	Lung cancer cells	Protein	Differential centrifugation FACS	Microvesicles
589	Vesiclepedia_504	23465879	Homo sapiens	Lipidomic analysis of human placental Syncytiotrophoblast microvesicles in adverse pregnancy outcomes.	Placenta	Lipids	-	Microvesicles
590	Vesiclepedia_277	22030351	Homo sapiens	Expression of PTRF in PC-3 cells modulates cholesterol dynamics and the actin cytoskeleton impacting secretion pathways	Prostate cancer cells	Protein	Differential centrifugation	Exosomes
591	Vesiclepedia_1206	29127410	Homo sapiens	Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies.	Bronchial epithelial cells	Protein	Ultrafiltration Size exclusion chromatography	Extracellular vesicles
592	Vesiclepedia_1228	26154623	Homo sapiens	Size-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals	Plasma	Protein	Size exclusion chromatography	Extracellular vesicles
593	Vesiclepedia_83	20949044	Homo sapiens	Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line	Lung cancer cells	Protein miRNA	Differential centrifugation Filtration Ultracentrifugation	Exosomes
594	Vesiclepedia_1075	25104112	Homo sapiens	Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy.	Plasma	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Exosomes
595	Vesiclepedia_1009	23185418	Homo sapiens	Improved flow cytometric assessment reveals distinct microvesicle (cell-derived microparticle) signatures in joint diseases.	Synovial fluid	Protein	Filtration Ultracentrifugation	Microvesicles
596	Vesiclepedia_943	29207636	Homo sapiens	Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer.	Urine	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
597	Vesiclepedia_667	29956871	Homo sapiens	Expression analysis of extracellular microRNA in bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis	Bronchoalveolar lavage fluid	miRNA	Differential centrifugation Ultracentrifugation Filtration	Exosomes
598	Vesiclepedia_1161	22641613	Homo sapiens	Application of systems biology principles to protein biomarker discovery: urinary exosomal proteome in renal transplantation.	Urine	Protein	Differential centrifugation Ultracentrifugation	Exosomes
599	Vesiclepedia_570	26858453	Homo sapiens	Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes	Dendritic cells	Protein	Differential centrifugation Ultracentrifugation Immunobeads (CD63 PD)	Extracellular vesicles
600	Vesiclepedia_77	20224111	Homo sapiens	Proteomics analysis of bladder cancer exosomes.	Urine	Protein	Differential centrifugation Sucrose density gradient	Exosomes
601	Vesiclepedia_292	10415024	Homo sapiens	Activated human T cells release bioactive Fas ligand and APO2 ligand in microvesicles	T cells	Protein	Differential centrifugation Ultracentrifugation FACS	Microvesicles
602	Vesiclepedia_850	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
603	Vesiclepedia_727	25359493	Homo sapiens	Proteomic signatures of extracellular vesicles secreted by nonmineralizing and mineralizing human osteoblasts and stimulation of tumor cell growth.	Osteoblasts	Protein	Differential centrifugation Ultracentrifugation	Matrix vesicles
604	Vesiclepedia_926	25483805	Homo sapiens	Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties	Embryonic kidney cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
605	Vesiclepedia_939	29207636	Homo sapiens	Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer.	Urine	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
606	Vesiclepedia_576	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Breast cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
607	Vesiclepedia_13	15326289	Homo sapiens	Identification and proteomic profiling of exosomes in human urine.	Urine	Protein	Ultracentrifugation	Exosomes
608	Vesiclepedia_694	28842968	Homo sapiens	Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles.	Colorectal cancer cells	Protein	Differential centrifugation Ultracentrifugation	Microvesicles
609	Vesiclepedia_1035	29887978	Homo sapiens	Evaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing.	Serum	Protein miRNA	Exo-spin	Extracellular vesicles
610	Vesiclepedia_1033	29887978	Homo sapiens	Evaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing.	Serum	Protein miRNA	qEV size-exclusion column	Extracellular vesicles
611	Vesiclepedia_477	23056502	Homo sapiens	Identifying mRNA, MicroRNA and Protein Profiles of Melanoma Exosomes.	Melanoma cells	mRNA	-	Exosomes
612	Vesiclepedia_204	19011622	Homo sapiens	Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers	Serum	mRNA miRNA	Differential centrifugation Ultracentrifugation Filtration	Microvesicles
613	Vesiclepedia_1105	24391718	Homo sapiens	Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.	Prostate epithelial cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
614	Vesiclepedia_1160	22641613	Homo sapiens	Application of systems biology principles to protein biomarker discovery: urinary exosomal proteome in renal transplantation.	Urine	Protein	Differential centrifugation Ultracentrifugation	Exosomes
615	Vesiclepedia_1029	26378940	Homo sapiens	Redefining the Breast Cancer Exosome Proteome by Tandem Mass Tag Quantitative Proteomics and Multivariate Cluster Analysis.	Breast cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
616	Vesiclepedia_172	21859146	Homo sapiens	Identification of a conserved glycan signature for microvesicles	Melanoma cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Microvesicles
617	Vesiclepedia_626	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Ovarian cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
618	Vesiclepedia_747	29988836	Homo sapiens	Ultrafiltration and size exclusion chromatography combined with asymmetrical-flow field-flow fractionation for the isolation and characterisation of extracellular vesicles from urine	Urine	Protein	Filtration Size exclusion chromatography	Extracellular vesicles
619	Vesiclepedia_453	22635005	Homo sapiens	Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET.	Melanoma cells	Protein	-	Exosomes
620	Vesiclepedia_944	29207636	Homo sapiens	Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer.	Urine	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
621	Vesiclepedia_244	22148876	Homo sapiens	Proteomic analysis of microvesicles derived from human mesenchymal stem cells	Mesenchymal stem cells	Protein	Differential centrifugation Ultrafiltration Ultracentrifugation Density gradient centrifugation	Microvesicles
622	Vesiclepedia_1197	27883272	Homo sapiens	Circulating adipocyte-derived exosomal MicroRNAs associated with decreased insulin resistance after gastric bypass.	Plasma	miRNA Metabolites	ExoQuick	Exosomes
623	Vesiclepedia_505	23465879	Homo sapiens	Lipidomic analysis of human placental Syncytiotrophoblast microvesicles in adverse pregnancy outcomes.	Placenta	Lipids	-	Microvesicles
624	Vesiclepedia_734	25359493	Homo sapiens	Proteomic signatures of extracellular vesicles secreted by nonmineralizing and mineralizing human osteoblasts and stimulation of tumor cell growth.	Osteoblasts	Protein	Differential centrifugation Ultracentrifugation	Matrix vesicles
625	Vesiclepedia_931	29207636	Homo sapiens	Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer.	Urothelial cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
626	Vesiclepedia_1008	23463506	Homo sapiens	The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes.	T cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
627	Vesiclepedia_901	26100252	Homo sapiens	Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts	Chronic lymphocytic leukemia cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
628	Vesiclepedia_121	21276792	Homo sapiens	Morphologic and proteomic characterization of exosomes released by cultured extravillous trophoblast cells.	Trophoblast cells	Protein	Differential centrifugation Ultrafiltration Ultracentrifugation Density gradient centrifugation	Exosomes
629	Vesiclepedia_514	23539611	Homo sapiens	microRNA signature is altered in both human epididymis and seminal microvesicles following vasectomy.	Seminal fluid	miRNA	-	Microvesicles
630	Vesiclepedia_397	19413345	Homo sapiens	Proteomic analysis of malignant B-cell derived microparticles reveals CD148 as a potentially useful antigenic biomarker for mantle cell lymphoma diagnosis.	B cells	Protein	-	Microparticles
631	Vesiclepedia_923	25483805	Homo sapiens	Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties	Embryonic kidney cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
632	Vesiclepedia_49	14582906	Homo sapiens	Exosomes with major histocompatibility complex class II and co-stimulatory molecules are present in human BAL fluid.	Bronchoalveolar lavage fluid	Protein	Differential centrifugation Immunobeads (EpCAM)	Exosomes
633	Vesiclepedia_74	19381331	Homo sapiens	High levels of exosomes expressing CD63 and caveolin-1 in plasma of melanoma patients.	Melanoma cells	Protein	Differential centrifugation	Exosomes
634	Vesiclepedia_612	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Lung cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
635	Vesiclepedia_592	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Colorectal cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
636	Vesiclepedia_410	20052414	Homo sapiens	Nanostructural and transcriptomic analyses of human saliva derived exosomes.	Saliva	mRNA	-	Exosomes/Membrane vesicles
637	Vesiclepedia_615	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Lung cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
638	Vesiclepedia_57	17700640	Homo sapiens	CD24 is a marker of exosomes secreted into urine and amniotic fluid.	Urine	Protein	Differential centrifugation Sucrose density gradient	Exosomes
639	Vesiclepedia_611	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Lung cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
640	Vesiclepedia_1177	29854963	Homo sapiens	Genome-wide Profiling of Urinary Extracellular Vesicle microRNAs Associated With Diabetic Nephropathy in Type 1 Diabetes.	Urine	miRNA	qEV size-exclusion column	Extracellular vesicles
641	Vesiclepedia_666	29956871	Homo sapiens	Expression analysis of extracellular microRNA in bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis	Bronchoalveolar lavage fluid	miRNA	Differential centrifugation Ultracentrifugation Filtration	Microvesicles
642	Vesiclepedia_1179	29854963	Homo sapiens	Genome-wide Profiling of Urinary Extracellular Vesicle microRNAs Associated With Diabetic Nephropathy in Type 1 Diabetes.	Urine	miRNA	qEV size-exclusion column	Extracellular vesicles
643	Vesiclepedia_247	15741221	Homo sapiens	Tissue-factor-bearing microvesicles arise from lipid rafts and fuse with activated platelets to initiate coagulation	Plasma	Protein	Differential centrifugation Immunobeads (TF)	Microvesicles
644	Vesiclepedia_508	23511837	Homo sapiens	Differential protein profiling of renal cell carcinoma urinary exosomes.	Urine	Protein	-	Exosomes/Nanovesicles
645	Vesiclepedia_989	25261472	Homo sapiens	Complex N-linked glycans serve as a determinant for exosome/microvesicle cargo recruitment.	Melanoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes/Microvesicles
646	Vesiclepedia_942	29207636	Homo sapiens	Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer.	Urine	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
647	Vesiclepedia_857	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
648	Vesiclepedia_950	27601599	Homo sapiens	Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components.	Breast milk	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
649	Vesiclepedia_176	21788507	Homo sapiens	Hypoxia triggers a proangiogenic pathway involving cancer cell microvesicles and PAR-2-mediated heparin-binding EGF signaling in endothelial cells	Glioblastoma cells	Protein	Differential centrifugation	Microvesicles
650	Vesiclepedia_1239	25329303	Homo sapiens	Rapid isolation of extracellular vesicles from cell culture and biological fluids using a synthetic peptide with specific affinity for heat shock proteins.	Urine	Protein	Vn96 peptide precipitation	Extracellular vesicles
651	Vesiclepedia_105	21763319	Homo sapiens	Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells.	Pancreatic adenocarcinoma cells	Protein	Differential centrifugation Filtration Ultrafiltration Ultracentrifugation	Exosomes
652	Vesiclepedia_1034	29887978	Homo sapiens	Evaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing.	Serum	Protein miRNA	qEV size-exclusion column	Extracellular vesicles
653	Vesiclepedia_242	9151784	Homo sapiens	Transcellular activation of platelets and endothelial cells by bioactive lipids in platelet microparticles	Platelets	Lipids	Differential centrifugation	Microparticles
654	Vesiclepedia_1180	29854963	Homo sapiens	Genome-wide Profiling of Urinary Extracellular Vesicle microRNAs Associated With Diabetic Nephropathy in Type 1 Diabetes.	Urine	miRNA	qEV size-exclusion column	Extracellular vesicles
655	Vesiclepedia_888	24946052	Homo sapiens	Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment	Lung cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
656	Vesiclepedia_395	19413345	Homo sapiens	Proteomic analysis of malignant B-cell derived microparticles reveals CD148 as a potentially useful antigenic biomarker for mantle cell lymphoma diagnosis.	B cells	Protein	-	Microparticles
657	Vesiclepedia_739	25157233	Homo sapiens	Extravillous trophoblast cells-derived exosomes promote vascular smooth muscle cell migration.	Placenta	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
658	Vesiclepedia_468	23000592	Homo sapiens	In-depth analysis of the secretome identifies three major independent secretory pathways in differentiating human myoblasts.	Neonatal myoblast cells	Protein	-	Microvesicles/Nanovesicles
659	Vesiclepedia_1253	24939845	Homo sapiens	Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein.	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
660	Vesiclepedia_511	23521563	Homo sapiens	First identification of Ewing's sarcoma-derived extracellular vesicles and exploration of their biological and potential diagnostic implications.	Ewing's sarcoma cells	mRNA	-	Exosomes/Extracellular vesicles
661	Vesiclepedia_546	23983189	Homo sapiens	Characterization of Multiple Myeloma Vesicles by Label-Free Relative Quantitation.	B cells	Protein	-	Exosomes/Extracellular vesicles/Microvesicles
662	Vesiclepedia_264	18425114	Homo sapiens	Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells	Epidermoid carcinoma cells	Protein	Differential centrifugation Ultracentrifugation	Microvesicles
663	Vesiclepedia_1198	27883272	Homo sapiens	Circulating adipocyte-derived exosomal MicroRNAs associated with decreased insulin resistance after gastric bypass.	Serum	miRNA Metabolites	ExoQuick	Exosomes
664	Vesiclepedia_806	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
665	Vesiclepedia_67	19619303	Homo sapiens	Claudin-containing exosomes in the peripheral circulation of women with ovarian cancer.	Ovarian cancer cells	Protein	Differential centrifugation Sucrose density gradient	Exosomes
666	Vesiclepedia_1131	23954818	Homo sapiens	Qualitative changes in the proteome of extracellular vesicles accompanying cancer cell transition to mesenchymal state.	Squamous carcinoma cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
667	Vesiclepedia_971	22808001	Homo sapiens	Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment.	Serum	Protein	Filtration ExoQuick	Exosomes
668	Vesiclepedia_354	24115447	Homo sapiens	Comparative proteomics evaluation of plasma exosome isolation techniques and assessment of the stability of exosomes in normal human blood plasma	Plasma	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
669	Vesiclepedia_549	24009881	Homo sapiens	Quantitative proteomics of extracellular vesicles derived from human primary and metastatic colorectal cancer cells.	Colorectal cancer cells	Protein	-	Exosomes/Extracellular vesicles/Microvesicles/Ectosomes
670	Vesiclepedia_479	23082778	Homo sapiens	Comparative and Targeted Proteomic Analyses of Urinary Microparticles from Bladder Cancer and Hernia Patients.	Urine	Protein	-	Exosomes/Membrane vesicles
671	Vesiclepedia_394	19389847	Homo sapiens	Mesenchymal stem cell-derived microvesicles protect against acute tubular injury.	Mesenchymal stem cells	mRNA	-	Microvesicles
672	Vesiclepedia_478	23082778	Homo sapiens	Comparative and Targeted Proteomic Analyses of Urinary Microparticles from Bladder Cancer and Hernia Patients.	Urine	Protein	-	Exosomes/Membrane vesicles
673	Vesiclepedia_217	21293856	Homo sapiens	Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC	Serum	Protein	Differential centrifugation Filtration Ultrafiltration Ultracentrifugation Sucrose density gradient	Exosomes
674	Vesiclepedia_978	22808001	Homo sapiens	Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment.	Serum	Protein	Filtration ExoQuick	Exosomes
675	Vesiclepedia_852	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
676	Vesiclepedia_341	20615901	Homo sapiens	Export of microRNAs and microRNA-protective protein by mammalian cells	Epithelial cells	miRNA	Differential centrifugation	Exosomes
677	Vesiclepedia_1231	25503107	Homo sapiens	Tumor-derived microvesicles mediate human breast cancer invasion through differentially glycosylated EMMPRIN.	Breast cancer cells	Protein	Ultracentrifugation Filtration Density gradient centrifugation	Microvesicles
678	Vesiclepedia_488	23230278	Homo sapiens	Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids.	Colorectal cancer cells	Protein	-	Exosomes/Extracellular vesicles/Microvesicles
679	Vesiclepedia_473	23056467	Homo sapiens	Cause or Effect of Arteriogenesis: Compositional Alterations of Microparticles from CAD Patients Undergoing External Counterpulsation Therapy.	Plasma	Protein	-	Microparticles
680	Vesiclepedia_1251	24939845	Homo sapiens	Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein.	Leukemia cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
681	Vesiclepedia_220	10694520	Homo sapiens	Elevated levels of shed membrane microparticles with procoagulant potential in the peripheral circulating blood of patients with acute coronary syndromes	Plasma	Protein	Immunoaffinity [Annexin-V]	Microparticles
682	Vesiclepedia_122	21235781	Homo sapiens	Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages.	Saliva	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
683	Vesiclepedia_650	29188495	Homo sapiens	Protein Biomarkers and Neuroproteomics Characterization of Microvesicles/Exosomes from Human Cerebrospinal Fluid Following Traumatic Brain Injury.	Cerebrospinal fluid	Protein	Differential centrifugation Ultracentrifugation Sonication Filtration	Extracellular vesicles
684	Vesiclepedia_365	11878797	Homo sapiens	Phospholipid composition of cell-derived microparticles determined by one-dimensional high-performance thin-layer chromatography.	Plasma	Lipids	-	Microparticles
685	Vesiclepedia_1183	28684402	Homo sapiens	BRAFV600 inhibition alters the microRNA cargo in the vesicular secretome of malignant melanoma cells	Melanoma cells	miRNA	Differential centrifugation Filtration Ultracentrifugation	Extracellular vesicles
686	Vesiclepedia_750	29988836	Homo sapiens	Ultrafiltration and size exclusion chromatography combined with asymmetrical-flow field-flow fractionation for the isolation and characterisation of extracellular vesicles from urine	Urine	Protein	Filtration Size exclusion chromatography	Extracellular vesicles
687	Vesiclepedia_1291	19912576	Homo sapiens	HIV Nef is secreted in exosomes and triggers apoptosis in bystander CD4+ T cells.	Lymphoblasts	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
688	Vesiclepedia_789	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Embryonic kidney cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
689	Vesiclepedia_1110	24391718	Homo sapiens	Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
690	Vesiclepedia_1290	19912576	Homo sapiens	HIV Nef is secreted in exosomes and triggers apoptosis in bystander CD4+ T cells.	Lymphoblasts	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
691	Vesiclepedia_745	29988836	Homo sapiens	Ultrafiltration and size exclusion chromatography combined with asymmetrical-flow field-flow fractionation for the isolation and characterisation of extracellular vesicles from urine	Urine	Protein	Filtration Size exclusion chromatography	Extracellular vesicles
692	Vesiclepedia_500	23404715	Homo sapiens	Distinct lipid compositions of two types of human prostasomes.	Seminal fluid	Lipids	-	Prostasomes
693	Vesiclepedia_1175	29854963	Homo sapiens	Genome-wide Profiling of Urinary Extracellular Vesicle microRNAs Associated With Diabetic Nephropathy in Type 1 Diabetes.	Urine	miRNA	qEV size-exclusion column	Extracellular vesicles
694	Vesiclepedia_1044	27770278	Homo sapiens	Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease.	Glioblastoma cells	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Extracellular vesicles
695	Vesiclepedia_596	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Kidney cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
696	Vesiclepedia_47	17641064	Homo sapiens	Exosomes with immune modulatory features are present in human breast milk.	B cells	Protein	Differential centrifugation Filtration Sucrose density gradient	Exosomes
697	Vesiclepedia_722	25802036	Homo sapiens	Glioblastoma-derived extracellular vesicles modify the phenotype of monocytic cells.	Glioblastoma cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
698	Vesiclepedia_1049	28842968	Homo sapiens	Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles.	Colorectal cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
699	Vesiclepedia_139	22723089	Homo sapiens	Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes.	Prostate cancer cells	Protein	Sucrose density gradient	Exosomes
700	Vesiclepedia_1150	22807456	Homo sapiens	Quantitative proteomic analysis of exosomes from HIV-1-infected lymphocytic cells.	Lymphocytes	Protein	Differential centrifugation Ultracentrifugation	Exosomes
701	Vesiclepedia_497	23344721	Homo sapiens	miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.	Melanoma cells	mRNA	-	Microvesicles
702	Vesiclepedia_723	25802036	Homo sapiens	Glioblastoma-derived extracellular vesicles modify the phenotype of monocytic cells.	Glioblastoma cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
703	Vesiclepedia_1118	24391718	Homo sapiens	Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
704	Vesiclepedia_702	28811610	Homo sapiens	Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA.	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Apoptotic bodies
705	Vesiclepedia_287	12417540	Homo sapiens	Elevated numbers of tissue-factor exposing microparticles correlate with components of the metabolic syndrome in uncomplicated type 2 diabetes mellitus	Plasma	Protein	Differential centrifugation FACS	Microparticles
706	Vesiclepedia_409	20031610	Homo sapiens	Proteomics, metabolomics, and immunomics on microparticles derived from human atherosclerotic plaques.	Carotid atherosclerotic plaques	Protein	-	Microparticles
707	Vesiclepedia_125	21059916	Homo sapiens	Human tumor virus utilizes exosomes for intercellular communication.	Nasopharyngeal carcinoma cells	Protein	Differential centrifugation	Exosomes
708	Vesiclepedia_1060	30006486	Homo sapiens	The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells.	Astrocytoma cells	Protein	Filtration Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
709	Vesiclepedia_253	9126269	Homo sapiens	Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations	Leukemia cells	Protein	Differential centrifugation Sucrose density gradient	Microvesicles
710	Vesiclepedia_141	22723089	Homo sapiens	Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes.	Prostate cancer cells	Protein	Sucrose density gradient	Exosomes
711	Vesiclepedia_972	22808001	Homo sapiens	Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment.	Serum	Protein	Filtration ExoQuick	Exosomes
712	Vesiclepedia_856	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
713	Vesiclepedia_1123	24347249	Homo sapiens	Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation ExoQuick	Exosomes
714	Vesiclepedia_690	28170197	Homo sapiens	Enhanced Cardioprotection by Human Endometrium Mesenchymal Stem Cells Driven by Exosomal MicroRNA-21	Bone marrow mesenchymal stem cells	miRNA	Differential centrifugation Filtration Ultracentrifugation	Exosomes
715	Vesiclepedia_1190	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
716	Vesiclepedia_1271	24058411	Homo sapiens	Osteoprotegerin in exosome-like vesicles from human cultured tubular cells and urine.	Proximal tubular epithelial cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
717	Vesiclepedia_966	25844599	Homo sapiens	Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.	Serum	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
718	Vesiclepedia_46	17641064	Homo sapiens	Exosomes with immune modulatory features are present in human breast milk.	Breast milk	Protein	Differential centrifugation Filtration Sucrose density gradient	Exosomes
719	Vesiclepedia_507	23511837	Homo sapiens	Differential protein profiling of renal cell carcinoma urinary exosomes.	Urine	Protein	-	Exosomes/Nanovesicles
720	Vesiclepedia_717	26148937	Homo sapiens	Proteomics profiling of cholangiocarcinoma exosomes: A potential role of oncogenic protein transferring in cancer progression.	Cholangiocytes	Protein	Differential centrifugation Ultracentrifugation Filtration	Exosomes
721	Vesiclepedia_882	29955024	Homo sapiens	Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells	Myeloid leukemia cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
722	Vesiclepedia_1084	25104112	Homo sapiens	Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy.	Plasma	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Exosomes
723	Vesiclepedia_744	29988836	Homo sapiens	Ultrafiltration and size exclusion chromatography combined with asymmetrical-flow field-flow fractionation for the isolation and characterisation of extracellular vesicles from urine	Urine	Protein	Filtration Size exclusion chromatography	Extracellular vesicles
724	Vesiclepedia_848	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
725	Vesiclepedia_1090	25065644	Homo sapiens	Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells.	Duodenal cancer cells	Protein	Differential centrifugation Filtration Ultrafiltration	Exosomes
726	Vesiclepedia_1243	25261722	Homo sapiens	Inflammatory cytokines, interleukin-1 beta and tumor necrosis factor-alpha, upregulated in glioblastoma multiforme, raise the levels of CRYAB in exosomes secreted by U373 glioma cells.	Glioblastoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
727	Vesiclepedia_221	9918520	Homo sapiens	Shed membrane microparticles with procoagulant potential in human atherosclerotic plaques: a role for apoptosis in plaque thrombogenicity	Atherosclerotic plaques	Protein Lipids	Differential centrifugation Immunoaffinity [Annexin-V]	Apoptotic bodies
728	Vesiclepedia_862	25776846	Homo sapiens	Human thymic epithelial primary cells produce exosomes carrying tissue-restricted antigens	Epithelial cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
729	Vesiclepedia_16	9685355	Homo sapiens	Selective enrichment of tetraspan proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B-lymphocytes.	B cells	Protein	Differential centrifugation Sucrose density gradient	Exosomes
730	Vesiclepedia_584	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Brain cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
731	Vesiclepedia_1266	24310399	Homo sapiens	Extracellular vesicles modulate the glioblastoma microenvironment via a tumor suppression signaling network directed by miR-1.	Glioblastoma cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Extracellular vesicles
732	Vesiclepedia_298	12796750	Homo sapiens	High levels of circulating endothelial microparticles in patients with acute coronary syndromes	Plasma	Protein	Differential centrifugation FACS	Microparticles
733	Vesiclepedia_682	29148239	Homo sapiens	Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants.	Umblical cord mesenchymal stem cells	Protein	Differential centrifugation Ultracentrifugation Sonication Filtration	Microvesicles
734	Vesiclepedia_120	21362503	Homo sapiens	Protein profile of exosomes from trabecular meshwork cells.	Aqueous humor	Protein	Differential centrifugation Sucrose density gradient	Exosomes
735	Vesiclepedia_604	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Leukemia cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
736	Vesiclepedia_234	10648405	Homo sapiens	Cellular origin and procoagulant properties of microparticles in meningococcal sepsis	Plasma	Protein	Differential centrifugation FACS	Microparticles
737	Vesiclepedia_337	20976003	Homo sapiens	Selective release of microRNA species from normal and malignant mammary epithelial cells	Breast cancer cells	miRNA	Differential centrifugation Filtration	Exosomes
738	Vesiclepedia_965	25844599	Homo sapiens	Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.	Serum	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
739	Vesiclepedia_1153	22057275	Homo sapiens	Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease.	Neuroblastoma cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
740	Vesiclepedia_1014	22711894	Homo sapiens	Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages.	Macrophages	Protein Lipids	Differential centrifugation Filtration Ultracentrifugation	Exosomes
741	Vesiclepedia_749	29988836	Homo sapiens	Ultrafiltration and size exclusion chromatography combined with asymmetrical-flow field-flow fractionation for the isolation and characterisation of extracellular vesicles from urine	Urine	Protein	Filtration Size exclusion chromatography	Extracellular vesicles
742	Vesiclepedia_548	24009880	Homo sapiens	Characterization of mRNA and microRNA in human mast cell-derived exosomes and their transfer to other mast cells and blood CD34 progenitor cells.	Mast cells	mRNA	-	Exosomes/Extracellular vesicles
743	Vesiclepedia_349	22285593	Homo sapiens	Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes.	Colorectal cancer cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
744	Vesiclepedia_347	22285593	Homo sapiens	Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes.	Colorectal cancer cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
745	Vesiclepedia_269	12757771	Homo sapiens	Endothelial cells release phenotypically and quantitatively distinct microparticles in activation and apoptosis	Endothelial cells	Protein	Differential centrifugation FACS	Microparticles
746	Vesiclepedia_614	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Lung cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
747	Vesiclepedia_733	25359493	Homo sapiens	Proteomic signatures of extracellular vesicles secreted by nonmineralizing and mineralizing human osteoblasts and stimulation of tumor cell growth.	Osteoblasts	Protein	Differential centrifugation Ultracentrifugation	Matrix vesicles
748	Vesiclepedia_982	25458527	Homo sapiens	Benchtop isolation and characterization of functional exosomes by sequential filtration	Breast cancer cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
749	Vesiclepedia_227	2942561	Homo sapiens	Platelet surface glycoproteins. Studies on resting and activated platelets and platelet membrane microparticles in normal subjects, and observations in patients during adult respiratory distress syndrome and cardiac surgery	Plasma	Protein	Differential centrifugation	Microparticles
750	Vesiclepedia_173	21859146	Homo sapiens	Identification of a conserved glycan signature for microvesicles	Breast milk	Protein	Differential centrifugation Filtration Ultracentrifugation	Microvesicles
751	Vesiclepedia_104	21763319	Homo sapiens	Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells.	Pancreatic adenocarcinoma cells	Protein	Differential centrifugation Filtration Ultrafiltration Ultracentrifugation	Exosomes
752	Vesiclepedia_1072	29937354	Homo sapiens	Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors.	Glioblastoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
753	Vesiclepedia_203	19011622	Homo sapiens	Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers	Glioblastoma cells	Protein miRNA mRNA	Differential centrifugation Ultracentrifugation Filtration	Microvesicles
754	Vesiclepedia_1159	20409149	Homo sapiens	Transdifferentiated circulating monocytes release exosomes containing 14-3-3 proteins with matrix metalloproteinase-1 stimulating effect for dermal fibroblasts.	Keratinocytes	Protein	Differential centrifugation Filtration Ultrafiltration Ultracentrifugation Sucrose density gradient	Exosomes
755	Vesiclepedia_574	27601599	Homo sapiens	Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components	Breast milk	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
756	Vesiclepedia_581	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Brain cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
757	Vesiclepedia_1207	29127410	Homo sapiens	Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies.	Bronchial epithelial cells	Protein	Ultrafiltration Size exclusion chromatography	Extracellular vesicles
758	Vesiclepedia_377	18346024	Homo sapiens	The proteome of red cell membranes and vesicles during storage in blood bank conditions.	Red blood cells	Protein	-	Microvesicles/Nanovesicles
759	Vesiclepedia_517	23585443	Homo sapiens	Proteome profiling of exosomes derived from human primary and metastatic colorectal cells reveal differential expression of key metastatic factors and signal transduction components.	Colorectal cancer cells	Protein	-	Exosomes/Membrane vesicles
760	Vesiclepedia_941	29207636	Homo sapiens	Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer.	Urine	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
761	Vesiclepedia_1121	24347249	Homo sapiens	Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation ExoQuick	Exosomes
762	Vesiclepedia_725	25471207	Homo sapiens	Intraluminal proteome and peptidome of human urinary extracellular vesicles.	Urine	Protein	Differential centrifugation Hydrostatic filtration dialysis Ultrafiltration	Exosomes
763	Vesiclepedia_133	19188015	Homo sapiens	Systemic presence and tumor-growth promoting effect of ovarian carcinoma released exosomes	Ovarian cancer cells	Protein Lipids	Differential centrifugation Sucrose density gradient	Exosomes
764	Vesiclepedia_599	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Kidney cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
765	Vesiclepedia_808	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
766	Vesiclepedia_499	23404715	Homo sapiens	Distinct lipid compositions of two types of human prostasomes.	Seminal fluid	Lipids	-	Prostasomes
767	Vesiclepedia_909	29207636	Homo sapiens	Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer	Transitional carcinoma cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
768	Vesiclepedia_1113	24391718	Homo sapiens	Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
769	Vesiclepedia_859	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer	Plasma	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
770	Vesiclepedia_803	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
771	Vesiclepedia_597	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Kidney cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
772	Vesiclepedia_487	23230278	Homo sapiens	Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids.	Colorectal cancer cells	Protein	-	Exosomes/Extracellular vesicles/Microvesicles
773	Vesiclepedia_565	26858453	Homo sapiens	Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes	Dendritic cells	Protein	Differential centrifugation Ultracentrifugation OptiPrep density gradient	Exosomes
774	Vesiclepedia_951	27601599	Homo sapiens	Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components.	Breast milk	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
775	Vesiclepedia_1214	29127410	Homo sapiens	Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies.	Bronchial epithelial cells	Protein	Ultracentrifugation	Extracellular vesicles
776	Vesiclepedia_282	19234131	Homo sapiens	Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR	Lung cancer cells	Protein	Differential centrifugation	Microvesicles
777	Vesiclepedia_846	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
778	Vesiclepedia_954	27601599	Homo sapiens	Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components.	Breast milk	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
779	Vesiclepedia_603	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Leukemia cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
780	Vesiclepedia_494	23344721	Homo sapiens	miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.	Glioblastoma cells	mRNA	-	Microvesicles
781	Vesiclepedia_738	25157233	Homo sapiens	Extravillous trophoblast cells-derived exosomes promote vascular smooth muscle cell migration.	Placenta choriocarcinoma cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
782	Vesiclepedia_447	22444574	Homo sapiens	Proteomic analysis of microvesicles in human saliva by gel electrophoresis with liquid chromatography-mass spectrometry.	Saliva	Protein	-	Exosomes/Microvesicles
783	Vesiclepedia_63	19056867	Homo sapiens	Large-scale proteomics and phosphoproteomics of urinary exosomes.	Urine	Protein	Differential centrifugation	Exosomes
784	Vesiclepedia_879	29955024	Homo sapiens	Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells	Myeloid leukemia cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
785	Vesiclepedia_698	28811610	Homo sapiens	Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA.	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
786	Vesiclepedia_907	29207636	Homo sapiens	Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer	Transitional papilloma cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
787	Vesiclepedia_902	26100252	Homo sapiens	Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts	Chronic lymphocytic leukemia cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
788	Vesiclepedia_595	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Kidney cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
789	Vesiclepedia_634	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Prostate cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
790	Vesiclepedia_622	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Melanoma cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
791	Vesiclepedia_53	14975938	Homo sapiens	Proteomic analysis of exosomes isolated from human malignant pleural effusions.	Malignant pleural effusions	Protein	Differential centrifugation Sucrose density gradient	Exosomes
792	Vesiclepedia_271	10903724	Homo sapiens	Follicular dendritic cells carry MHC class II-expressing microvesicles at their surface	B cells	Protein	Differential centrifugation	Exosomes
793	Vesiclepedia_708	28811610	Homo sapiens	Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA.	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Microvesicles
794	Vesiclepedia_607	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Leukemia cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
795	Vesiclepedia_1089	25065644	Homo sapiens	Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells.	Duodenal cancer cells	Protein	Differential centrifugation Filtration Ultrafiltration	Exosomes
796	Vesiclepedia_887	25102470	Homo sapiens	Examination of the specificity of tumor cell derived exosomes with tumor cells in vitro	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
797	Vesiclepedia_788	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Embryonic kidney cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
798	Vesiclepedia_456	22682234	Homo sapiens	Microparticle conferred microRNA profiles - implications in the transfer and dominance of cancer traits.	Breast cancer cells	miRNA	-	Membrane vesicles/Microparticles
799	Vesiclepedia_807	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
800	Vesiclepedia_182	20668554	Homo sapiens	Microvesicles derived from adult human bone marrow and tissue specific mesenchymal stem cells shuttle selected pattern of miRNAs	Liver stem cells	miRNA	Differential centrifugation Ultracentrifugation	Microvesicles
801	Vesiclepedia_621	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Melanoma cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
802	Vesiclepedia_1081	25104112	Homo sapiens	Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy.	Plasma	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Exosomes
803	Vesiclepedia_709	28811610	Homo sapiens	Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA.	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Apoptotic bodies
804	Vesiclepedia_878	29955024	Homo sapiens	Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells	Embryonic kidney cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
805	Vesiclepedia_492	23333927	Homo sapiens	Characterization and proteomic analysis of ovarian cancer-derived exosomes.	Ovarian cancer cells	Protein	-	Exosomes
806	Vesiclepedia_276	12021310	Homo sapiens	Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles	Melanoma cells	Protein	Differential centrifugation Ultracentrifugation	Microvesicles
807	Vesiclepedia_970	25844599	Homo sapiens	Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.	Serum	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
808	Vesiclepedia_696	28842968	Homo sapiens	Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles.	Colorectal cancer cells	Protein	Differential centrifugation Ultracentrifugation	Microvesicles
809	Vesiclepedia_729	25359493	Homo sapiens	Proteomic signatures of extracellular vesicles secreted by nonmineralizing and mineralizing human osteoblasts and stimulation of tumor cell growth.	Osteoblasts	Protein	Differential centrifugation Ultracentrifugation	Matrix vesicles
810	Vesiclepedia_1080	25104112	Homo sapiens	Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy.	Plasma	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Exosomes
811	Vesiclepedia_1246	25167841	Homo sapiens	Antibody-coupled monolithic silica microtips for highthroughput molecular profiling of circulating exosomes.	Serum	Protein	CD9 antibody to Mass Spectrometric Immunoassay monolith pipette tips	Exosomes
812	Vesiclepedia_840	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
813	Vesiclepedia_1241	25329303	Homo sapiens	Rapid isolation of extracellular vesicles from cell culture and biological fluids using a synthetic peptide with specific affinity for heat shock proteins.	Urine	Protein	Vn96 peptide precipitation	Extracellular vesicles
814	Vesiclepedia_1270	24218614	Homo sapiens	Unexpected gain of function for the scaffolding protein plectin due to mislocalization in pancreatic cancer.	Pancreatic adenocarcinoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
815	Vesiclepedia_310	22148876	Homo sapiens	Proteomic analysis of microvesicles derived from human mesenchymal stem cells	Mesenchymal stem cells	Protein	Differential centrifugation Ultrafiltration Ultracentrifugation Density gradient centrifugation	Microvesicles
816	Vesiclepedia_303	19930720	Homo sapiens	Colorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells	Colorectal cancer cells	Protein mRNA	Differential centrifugation Ultrafiltration OptiPrep density gradient	Microvesicles
817	Vesiclepedia_689	28170197	Homo sapiens	Enhanced Cardioprotection by Human Endometrium Mesenchymal Stem Cells Driven by Exosomal MicroRNA-21	Adipose-derived mesenchymal stem cells	miRNA	Differential centrifugation Filtration Ultracentrifugation	Exosomes
818	Vesiclepedia_586	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Brain cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
819	Vesiclepedia_312	15499615	Homo sapiens	Microvesicles derived from activated platelets induce metastasis and angiogenesis in lung cancer	Lung cancer cells	Protein	Differential centrifugation FACS	Microvesicles
820	Vesiclepedia_255	9126269	Homo sapiens	Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations	Burkitt's lymphoma	Protein	Differential centrifugation Sucrose density gradient	Microvesicles
821	Vesiclepedia_1134	23861904	Homo sapiens	Exosomal signaling during hypoxia mediates microvascular endothelial cell migration and vasculogenesis.	Placental mesenchymal stem cells	Protein	Differential centrifugation Ultracentrifugation Ultrafiltration Density gradient centrifugation	Exosomes
822	Vesiclepedia_1043	27770278	Homo sapiens	Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease.	Glioblastoma cells	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Extracellular vesicles
823	Vesiclepedia_1218	27872147	Homo sapiens	Primary Human and Rat .-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity.	Islets	Protein	Differential centrifugation Ultracentrifugation	Exosomes
824	Vesiclepedia_241	16192427	Homo sapiens	Circulating endothelial microparticles are associated with vascular dysfunction in patients with end-stage renal failure	Plasma	Protein	Differential centrifugation FACS	Microparticles
825	Vesiclepedia_587	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Colorectal cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
826	Vesiclepedia_222	12514112	Homo sapiens	Intravascular tissue factor initiates coagulation via circulating microvesicles and platelets	Plasma	Protein	Differential centrifugation FACS	Microvesicles
827	Vesiclepedia_1187	28326167	Homo sapiens	Residual urinary extracellular vesicles in ultracentrifugation supernatants after hydrostatic filtration dialysis enrichment.	Urine	Protein	Hydrostatic filtration dialysis Differential centrifugation Ultracentrifugation	Extracellular vesicles
828	Vesiclepedia_754	29963269	Homo sapiens	Mining of potential microRNAs with clinical correlation - regulation of syndecan-1 expression by miR-122-5p altered mobility of breast cancer cells and possible correlation with liver injury	Hepatoma cells	Protein	Total Exosome Isolation Kit Differential centrifugation	Exosomes
829	Vesiclepedia_753	29963269	Homo sapiens	Mining of potential microRNAs with clinical correlation - regulation of syndecan-1 expression by miR-122-5p altered mobility of breast cancer cells and possible correlation with liver injury	Hepatoma cells	miRNA	Total Exosome Isolation Kit Differential centrifugation	Exosomes
830	Vesiclepedia_881	29955024	Homo sapiens	Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells	Myeloid leukemia cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
831	Vesiclepedia_437	22106071	Homo sapiens	Proteomic analysis of urine exosomes by multidimensional protein identification technology (MudPIT).	Urine	Protein	-	Exosomes/Membrane vesicles
832	Vesiclepedia_1289	19912576	Homo sapiens	HIV Nef is secreted in exosomes and triggers apoptosis in bystander CD4+ T cells.	Cervix carcinoma cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
833	Vesiclepedia_623	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Melanoma cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
834	Vesiclepedia_551	24009886	Homo sapiens	Cellular stress conditions are reflected in the protein and RNA content of endothelial cell-derived exosomes.	Endothelial cells	Protein	-	Exosomes/Extracellular vesicles
835	Vesiclepedia_106	21763319	Homo sapiens	Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells.	Pancreatic adenocarcinoma cells	Protein	Differential centrifugation Filtration Ultrafiltration Ultracentrifugation	Exosomes
836	Vesiclepedia_1032	29887978	Homo sapiens	Evaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing.	Serum	Protein miRNA	exoEasy columns	Extracellular vesicles
837	Vesiclepedia_537	23818640	Homo sapiens	Modulation of B-cell exosome proteins by gamma herpesvirus infection.	B cells	Protein	-	Exosomes/Microvesicles/Oncosomes/Microparticles
838	Vesiclepedia_606	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Leukemia cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
839	Vesiclepedia_908	29207636	Homo sapiens	Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer	Transitional carcinoma cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
840	Vesiclepedia_311	22148876	Homo sapiens	Proteomic analysis of microvesicles derived from human mesenchymal stem cells	Mesenchymal stem cells	Protein	Differential centrifugation Ultrafiltration Ultracentrifugation Density gradient centrifugation	Microvesicles
841	Vesiclepedia_286	12417540	Homo sapiens	Elevated numbers of tissue-factor exposing microparticles correlate with components of the metabolic syndrome in uncomplicated type 2 diabetes mellitus	Plasma	Protein	Differential centrifugation FACS	Microparticles
842	Vesiclepedia_706	28811610	Homo sapiens	Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA.	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Microvesicles/Apoptotic bodies
843	Vesiclepedia_237	21293856	Homo sapiens	Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC	Melanoma cells	Protein	Differential centrifugation Filtration Ultrafiltration Ultracentrifugation Sucrose density gradient	Exosomes
844	Vesiclepedia_841	28881726	Homo sapiens	Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
845	Vesiclepedia_1229	26154623	Homo sapiens	Size-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals	Plasma	Protein	Size exclusion chromatography	Extracellular vesicles
846	Vesiclepedia_1132	23861904	Homo sapiens	Exosomal signaling during hypoxia mediates microvascular endothelial cell migration and vasculogenesis.	Placental mesenchymal stem cells	Protein	Differential centrifugation Ultracentrifugation Ultrafiltration Density gradient centrifugation	Exosomes
847	Vesiclepedia_243	22149170	Homo sapiens	The Protein Interaction Network of Extracellular Vesicles Derived from Human Colorectal Cancer Cells	Colorectal cancer cells	Protein	Differential centrifugation Ultrafiltration Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
848	Vesiclepedia_582	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Brain cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
849	Vesiclepedia_445	22418980	Homo sapiens	A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.	Urine	Protein	-	Exosomes
850	Vesiclepedia_378	18346024	Homo sapiens	The proteome of red cell membranes and vesicles during storage in blood bank conditions.	Red blood cells	Protein	-	Microvesicles/Nanovesicles
851	Vesiclepedia_1286	20880880	Homo sapiens	Proinflammatory exosomes in bronchoalveolar lavage fluid of patients with sarcoidosis.	Bronchoalveolar lavage fluid	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
852	Vesiclepedia_331	19627513	Homo sapiens	Exosomes from human saliva as a source of microRNA biomarkers	Saliva	Protein miRNA	Differential centrifugation Ultracentrifugation	Exosomes
853	Vesiclepedia_716	26317203	Homo sapiens	Progression of Osteosarcoma from a Non-Metastatic to a Metastatic Phenotype Is Causally Associated with Activation of an Autocrine and Paracrine uPA Axis.	Osteosarcoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
854	Vesiclepedia_938	29207636	Homo sapiens	Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer.	Urine	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
855	Vesiclepedia_145	22723089	Homo sapiens	Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes.	Prostate cancer cells	Protein	Sucrose density gradient	Exosomes
856	Vesiclepedia_55	12147373	Homo sapiens	Malignant effusions and immunogenic tumour-derived exosomes.	Malignant pleural effusions	Protein	Differential centrifugation Sucrose density gradient	Exosomes
857	Vesiclepedia_652	28290293	Homo sapiens	Comparative proteomic analysis of milk-derived exosomes in human and bovine colostrum and mature milk samples by iTRAQ-coupled LC-MS/MS.	Breast milk	Protein	Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation	Exosomes
858	Vesiclepedia_799	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Embryonic kidney cells	Protein	Differential centrifugation	Microvesicles
859	Vesiclepedia_975	22808001	Homo sapiens	Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment.	Serum	Protein	Filtration ExoQuick	Exosomes
860	Vesiclepedia_267	12757771	Homo sapiens	Endothelial cells release phenotypically and quantitatively distinct microparticles in activation and apoptosis	Endothelial cells	Protein	Differential centrifugation FACS	Microparticles
861	Vesiclepedia_474	23056502	Homo sapiens	Identifying mRNA, MicroRNA and Protein Profiles of Melanoma Exosomes.	Melanoma cells	miRNA	-	Exosomes
862	Vesiclepedia_1037	29887978	Homo sapiens	Evaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing.	Serum	Protein miRNA	miRCURY Exosome Isolation Kit	Extracellular vesicles
863	Vesiclepedia_602	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Leukemia cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
864	Vesiclepedia_751	29988836	Homo sapiens	Ultrafiltration and size exclusion chromatography combined with asymmetrical-flow field-flow fractionation for the isolation and characterisation of extracellular vesicles from urine	Urine	Protein	Filtration Size exclusion chromatography	Extracellular vesicles
865	Vesiclepedia_684	29148239	Homo sapiens	Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants.	Umblical cord mesenchymal stem cells	Protein	Differential centrifugation Ultracentrifugation Sonication Filtration	Microvesicles
866	Vesiclepedia_1162	22641613	Homo sapiens	Application of systems biology principles to protein biomarker discovery: urinary exosomal proteome in renal transplantation.	Urine	Protein	Differential centrifugation Ultracentrifugation	Exosomes
867	Vesiclepedia_1196	27883272	Homo sapiens	Circulating adipocyte-derived exosomal MicroRNAs associated with decreased insulin resistance after gastric bypass.	Plasma	miRNA Metabolites	ExoQuick	Exosomes
868	Vesiclepedia_610	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Lung cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
869	Vesiclepedia_906	29207636	Homo sapiens	Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer	Urothelial cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
870	Vesiclepedia_1222	26272980	Homo sapiens	Proteomic Profiling of Detergent Resistant Membranes (Lipid Rafts) of Prostasomes	Seminal plasma	Protein	Ultracentrifugation Density gradient centrifugation	Prostasomes
871	Vesiclepedia_697	28842968	Homo sapiens	Insulin Mediated Activation of PI3K/Akt Signalling Pathway Modifies the Proteomic Cargo of Extracellular Vesicles.	Colorectal cancer cells	Protein	Differential centrifugation Ultracentrifugation	Microvesicles
872	Vesiclepedia_201	21606166	Homo sapiens	Blast-derived microvesicles in sera from patients with acute myeloid leukemia suppress natural killer cell function via membrane-associated transforming growth factor-beta2	Serum	Protein	Size exclusion chromatography Ultracentrifugation	Microvesicles
873	Vesiclepedia_385	18563738	Homo sapiens	Comparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles.	Endothelial cells	Protein	-	Microparticles
874	Vesiclepedia_894	24946052	Homo sapiens	Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment	Lung cancer cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
875	Vesiclepedia_683	29148239	Homo sapiens	Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants.	Umblical cord mesenchymal stem cells	Protein	Differential centrifugation Ultracentrifugation Sonication Filtration	Microvesicles
876	Vesiclepedia_609	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Lung cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
877	Vesiclepedia_280	15499615	Homo sapiens	Microvesicles derived from activated platelets induce metastasis and angiogenesis in lung cancer	Lung cancer cells	Protein mRNA	Differential centrifugation FACS	Microvesicles
878	Vesiclepedia_1088	25065644	Homo sapiens	Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells.	Duodenal cancer cells	Protein	Differential centrifugation Filtration Ultrafiltration	Exosomes
879	Vesiclepedia_1124	24347249	Homo sapiens	Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules.	Prostate cancer cells	Protein	Differential centrifugation Ultracentrifugation ExoQuick	Exosomes
880	Vesiclepedia_348	22285593	Homo sapiens	Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes.	Colorectal cancer cells	Protein	Differential centrifugation Filtration Immunoaffinity (EpCAM) Ultracentrifugation	Exosomes
881	Vesiclepedia_246	18425114	Homo sapiens	Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells	Glioblastoma cells	Protein	Differential centrifugation Ultracentrifugation	Microvesicles
882	Vesiclepedia_1227	26154623	Homo sapiens	Size-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals	Plasma	Protein	Size exclusion chromatography	Extracellular vesicles
883	Vesiclepedia_1065	29963299	Homo sapiens	Enrichment of extracellular vesicles from human synovial fluid using size exclusion chromatography.	Synovial fluid	Protein	Size exclusion chromatography	Extracellular vesicles
884	Vesiclepedia_84	20949044	Homo sapiens	Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line	Lung cancer cells	miRNA	Differential centrifugation Filtration Ultracentrifugation	Exosomes
885	Vesiclepedia_713	28811610	Homo sapiens	Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA.	T cells	Protein	Differential centrifugation Filtration Ultracentrifugation Density gradient centrifugation	Exosomes
886	Vesiclepedia_1233	25469510	Homo sapiens	GAIP interacting protein C-terminus regulates autophagy and exosome biogenesis of pancreatic cancer through metabolic pathways.	Pancreatic cancer cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes
887	Vesiclepedia_398	19530224	Homo sapiens	Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes.	Keratinocytes	Protein	-	Exosomes
888	Vesiclepedia_1135	23861904	Homo sapiens	Exosomal signaling during hypoxia mediates microvascular endothelial cell migration and vasculogenesis.	Placental mesenchymal stem cells	Protein	Differential centrifugation Ultracentrifugation Ultrafiltration Density gradient centrifugation	Exosomes
889	Vesiclepedia_493	23333927	Homo sapiens	Characterization and proteomic analysis of ovarian cancer-derived exosomes.	Ovarian cancer cells	Protein	-	Exosomes
890	Vesiclepedia_295	10233897	Homo sapiens	Elevated levels of circulating procoagulant microparticles in patients with paroxysmal nocturnal hemoglobinuria and aplastic anemia	Platelets	Lipids	Differential centrifugation FACS	Microparticles
891	Vesiclepedia_721	26148937	Homo sapiens	Proteomics profiling of cholangiocarcinoma exosomes: A potential role of oncogenic protein transferring in cancer progression.	Cholangiocarcinoma cells	Protein	Differential centrifugation Ultracentrifugation Filtration	Exosomes
892	Vesiclepedia_988	25261472	Homo sapiens	Complex N-linked glycans serve as a determinant for exosome/microvesicle cargo recruitment.	Melanoma cells	Protein	Differential centrifugation Ultracentrifugation	Exosomes/Microvesicles
893	Vesiclepedia_214	21364924	Homo sapiens	Thermal- and oxidative stress causes enhanced release of NKG2D ligand-bearing immunosuppressive exosomes in leukemia/lymphoma T and B cells	T cells	Protein	Differential centrifugation Ultracentrifugation Filtration Sucrose density gradient FACS	Exosomes
894	Vesiclepedia_383	18373357	Homo sapiens	Isolation and identification of potential urinary microparticle biomarkers of bladder cancer.	Urine	Protein	-	Microparticles
895	Vesiclepedia_885	29955024	Homo sapiens	Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells	Myeloid leukemia cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
896	Vesiclepedia_905	29207636	Homo sapiens	Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer	Bladder cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
897	Vesiclepedia_1185	28042326	Homo sapiens	Exosomes derived from miR-140-5p-overexpressing human synovial mesenchymal stem cells enhance cartilage tissue regeneration and prevent osteoarthritis of the knee in a rat model.	Synovial mesenchymal stem cells	miRNA	Differential centrifugation Filtration Sucrose density gradient	Exosomes
898	Vesiclepedia_1059	30006486	Homo sapiens	The impact of oncogenic EGFRvIII on the proteome of extracellular vesicles released from glioblastoma cells.	Astrocytoma cells	Protein	Filtration Ultracentrifugation Density gradient centrifugation	Extracellular vesicles
899	Vesiclepedia_159	21630462	Homo sapiens	Proteomic analysis of microvesicles derived from human colorectal cancer ascites	Ascites	Protein	Differential centrifugation Sucrose density gradient OptiPrep density gradient	Microvesicles
900	Vesiclepedia_382	18373357	Homo sapiens	Isolation and identification of potential urinary microparticle biomarkers of bladder cancer.	Urine	Protein	-	Microparticles
901	Vesiclepedia_1205	27780738	Homo sapiens	Next-generation sequencing-based small RNA profiling of cerebrospinal fluid exosomes.	Serum	miRNA	Differential centrifugation Ultracentrifugation	Exosomes
902	Vesiclepedia_386	18563738	Homo sapiens	Comparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles.	Endothelial cells	Protein	-	Microparticles
903	Vesiclepedia_297	12796750	Homo sapiens	High levels of circulating endothelial microparticles in patients with acute coronary syndromes	Plasma	Protein	Differential centrifugation FACS	Microparticles
904	Vesiclepedia_110	21601258	Homo sapiens	Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage.	Ascites	Protein miRNA	Differential centrifugation Sucrose density gradient	Exosomes
905	Vesiclepedia_1028	26378940	Homo sapiens	Redefining the Breast Cancer Exosome Proteome by Tandem Mass Tag Quantitative Proteomics and Multivariate Cluster Analysis.	Breast cancer cells	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
906	Vesiclepedia_225	10393703	Homo sapiens	In vitro generation of endothelial microparticles and possible prothrombotic activity in patients with lupus anticoagulant	Plasma	Protein	Differential centrifugation	Microparticles
907	Vesiclepedia_1273	24058411	Homo sapiens	Osteoprotegerin in exosome-like vesicles from human cultured tubular cells and urine.	Urine	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
908	Vesiclepedia_625	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Melanoma cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
909	Vesiclepedia_1086	25065644	Homo sapiens	Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human metastatic duodenal cancer cells.	Duodenal cancer cells	Protein	Differential centrifugation Filtration Ultrafiltration	Exosomes
910	Vesiclepedia_428	21515422	Homo sapiens	Proteomic characterization of biogenesis and functions of matrix vesicles released from mineralizing human osteoblast-like cells.	Osteosarcoma cells	Protein	-	Matrix vesicles
911	Vesiclepedia_1117	24391718	Homo sapiens	Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.	Prostate epithelial cells	Protein	Differential centrifugation Ultracentrifugation Density gradient centrifugation	Exosomes
912	Vesiclepedia_787	29953723	Homo sapiens	Stimulation of exosome release by extracellular DNA is conserved across multiple cell types	Embryonic kidney cells	Protein	Differential centrifugation Filtration Ultracentrifugation	Exosomes
913	Vesiclepedia_367	12746840	Homo sapiens	Proteomic analysis of human prostasomes.	Seminal fluid	Protein	-	Prostasomes
914	Vesiclepedia_390	19158352	Homo sapiens	Characterization of PKD protein-positive exosome-like vesicles.	Urine	Protein	-	Exosomes/Membrane particles
915	Vesiclepedia_973	22808001	Homo sapiens	Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment.	Serum	Protein	Filtration ExoQuick	Exosomes
916	Vesiclepedia_593	27894104	Homo sapiens	Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.	Colorectal cancer cells	Protein	Differential centrifugation Polymer-based precipitation Ultracentrifugation	Extracellular vesicles
917	Vesiclepedia_730	25359493	Homo sapiens	Proteomic signatures of extracellular vesicles secreted by nonmineralizing and mineralizing human osteoblasts and stimulation of tumor cell growth.	Osteoblasts	Protein	Differential centrifugation Ultracentrifugation	Matrix vesicles
918	Vesiclepedia_252	9126269	Homo sapiens	Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations	T cells	Protein	Differential centrifugation Sucrose density gradient	Microvesicles
919	Vesiclepedia_685	29148239	Homo sapiens	Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants.	Umblical cord mesenchymal stem cells	Protein	Differential centrifugation Ultracentrifugation Sonication Filtration	Microvesicles
920	Vesiclepedia_564	26858453	Homo sapiens	Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes	Dendritic cells	Protein	Differential centrifugation Ultracentrifugation OptiPrep density gradient	Exosomes
921	Vesiclepedia_936	29207636	Homo sapiens	Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer.	Urine	Protein	Differential centrifugation Ultracentrifugation	Extracellular vesicles
922	Vesiclepedia_686	29148239	Homo sapiens	Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants.	Umblical cord mesenchymal stem cells	Protein	Differential centrifugation Ultracentrifugation Sonication Filtration	Microvesicles