miRNA description for hsa-miR-335-5p
miRNA accession hsa-miR-335-5p
Species Homo sapiens
 hsa-miR-335-5p identified in exosomes derived from the following tissue/cell type
Cerebrospinal fluid [Exosomes] 27780738   
Cerebrospinal fluid [Exosomes] 27780738   
Cerebrospinal fluid [Exosomes] 27780738   
Colorectal cancer cells [Small extracellular vesicles] 34887515   
Colorectal cancer cells [Exomeres] 34887515   
Colorectal cancer cells [Supermeres] 34887515   
Plasma [Extracellular vesicles/Exosomes] 31762962   
Plasma [Extracellular vesicles/Exosomes] 31762962   
Plasma [Extracellular vesicles/Exosomes] 31762962   
Posterior longitudinal ligament [Small extracellular vesicles] 35513391   
Posterior longitudinal ligament [Small extracellular vesicles] 35513391   
Serum [Exosomes] 27780738   
Serum [Exosomes] 27780738   
Serum [Exosomes] 27780738   
Serum [Exosomes] Unpublished / Not applicable
Urine [Extracellular vesicles] 29854963   
Urine [Extracellular vesicles] 29854963   
 Experiment description of studies that identified hsa-miR-335-5p in exosomes
1
Experiment ID1200
Identified moleculemiRNA
Identification method Next generation sequencing
PubMed ID 27780738   
OrganismHomo sapiens
Experiment descriptionNext-generation sequencing-based small RNA profiling of cerebrospinal fluid exosomes.
AuthorsYagi Y, Ohkubo T, Kawaji H, Machida A, Miyata H, Goda S, Roy S, Hayashizaki Y, Suzuki H, Yokota T.
Journal name Neurosci Lett.
Publication year2017
SampleCerebrospinal fluid
Sample nameHealthy donor 1
Molecules identified in the studymiRNA
Methods used in the studyNext generation sequencing
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2
Experiment ID1201
Identified moleculemiRNA
Identification method Next generation sequencing
PubMed ID 27780738   
OrganismHomo sapiens
Experiment descriptionNext-generation sequencing-based small RNA profiling of cerebrospinal fluid exosomes.
AuthorsYagi Y, Ohkubo T, Kawaji H, Machida A, Miyata H, Goda S, Roy S, Hayashizaki Y, Suzuki H, Yokota T.
Journal name Neurosci Lett.
Publication year2017
SampleCerebrospinal fluid
Sample nameHealthy donor 2
Molecules identified in the studymiRNA
Methods used in the studyNext generation sequencing
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3
Experiment ID1202
Identified moleculemiRNA
Identification method Next generation sequencing
PubMed ID 27780738   
OrganismHomo sapiens
Experiment descriptionNext-generation sequencing-based small RNA profiling of cerebrospinal fluid exosomes.
AuthorsYagi Y, Ohkubo T, Kawaji H, Machida A, Miyata H, Goda S, Roy S, Hayashizaki Y, Suzuki H, Yokota T.
Journal name Neurosci Lett.
Publication year2017
SampleCerebrospinal fluid
Sample nameCerebrospinal fluid
Molecules identified in the studymiRNA
Methods used in the studyNext generation sequencing
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4
Experiment ID3338
Identified moleculemiRNA
Identification method RNA sequencing
PubMed ID 34887515   
OrganismHomo sapiens
Experiment descriptionSupermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
AuthorsZhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ.
Journal name Nat Cell Biol
Publication year2021
SampleColorectal cancer cells
Sample nameDiFi
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
Mass spectrometry
RNA sequencing
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5
Experiment ID3339
Identified moleculemiRNA
Identification method RNA sequencing
PubMed ID 34887515   
OrganismHomo sapiens
Experiment descriptionSupermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
AuthorsZhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ.
Journal name Nat Cell Biol
Publication year2021
SampleColorectal cancer cells
Sample nameDiFi
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
Mass spectrometry
ELISA
RNA sequencing
EV-TRACK -
6
Experiment ID3340
Identified moleculemiRNA
Identification method RNA sequencing
PubMed ID 34887515   
OrganismHomo sapiens
Experiment descriptionSupermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
AuthorsZhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ.
Journal name Nat Cell Biol
Publication year2021
SampleColorectal cancer cells
Sample nameDiFi
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
Mass spectrometry
ELISA
RNA sequencing
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7
Experiment ID2317
Identified moleculemiRNA
Identification method Small RNA sequencing
PubMed ID 31762962   
OrganismHomo sapiens
Experiment descriptionSmall RNA-sequence analysis of plasma-derived extracellular vesicle miRNAs in smokers and patients with chronic obstructive pulmonary disease as circulating biomarkers
AuthorsSundar IK, Li D, Rahman I.
Journal name J Extracell Vesicles
Publication year2019
SamplePlasma
Sample nameNon-smokers
Molecules identified in the studyProtein
small RNA
Methods used in the studyWestern blotting
Small RNA sequencing
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8
Experiment ID2318
Identified moleculemiRNA
Identification method Small RNA sequencing
PubMed ID 31762962   
OrganismHomo sapiens
Experiment descriptionSmall RNA-sequence analysis of plasma-derived extracellular vesicle miRNAs in smokers and patients with chronic obstructive pulmonary disease as circulating biomarkers
AuthorsSundar IK, Li D, Rahman I.
Journal name J Extracell Vesicles
Publication year2019
SamplePlasma
Sample nameSmokers
Molecules identified in the studyProtein
small RNA
Methods used in the studyWestern blotting
Small RNA sequencing
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9
Experiment ID2319
Identified moleculemiRNA
Identification method Small RNA sequencing
PubMed ID 31762962   
OrganismHomo sapiens
Experiment descriptionSmall RNA-sequence analysis of plasma-derived extracellular vesicle miRNAs in smokers and patients with chronic obstructive pulmonary disease as circulating biomarkers
AuthorsSundar IK, Li D, Rahman I.
Journal name J Extracell Vesicles
Publication year2019
SamplePlasma
Sample nameCOPD patients
Molecules identified in the studyProtein
small RNA
Methods used in the studyWestern blotting
Small RNA sequencing
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10
Experiment ID2739
Identified moleculemiRNA
Identification method RNA sequencing
PubMed ID 35513391   
OrganismHomo sapiens
Experiment descriptionSmall extracellular vesicle-mediated miR-320e transmission promotes osteogenesis in OPLL by targeting TAK1
AuthorsXu C, Zhang Z, Liu N, Li L, Zhong H, Wang R, Shi Q, Zhang Z, Wei L, Hu B, Zhang H, Shen X, Wang Y, Liu Y, Yuan W.
Journal name Nat Commun
Publication year2022
SamplePosterior longitudinal ligament
Sample nameOssicifation of posterior longitudinal ligament cells
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
RNA sequencing
qRT-PCR
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11
Experiment ID2740
Identified moleculemiRNA
Identification method RNA sequencing
PubMed ID 35513391   
OrganismHomo sapiens
Experiment descriptionSmall extracellular vesicle-mediated miR-320e transmission promotes osteogenesis in OPLL by targeting TAK1
AuthorsXu C, Zhang Z, Liu N, Li L, Zhong H, Wang R, Shi Q, Zhang Z, Wei L, Hu B, Zhang H, Shen X, Wang Y, Liu Y, Yuan W.
Journal name Nat Commun
Publication year2022
SamplePosterior longitudinal ligament
Sample namePosterior longitudinal ligament cells
Molecules identified in the studymiRNA
Methods used in the studyRNA sequencing
qRT-PCR
EV-TRACK -
12
Experiment ID1203
Identified moleculemiRNA
Identification method Next generation sequencing
PubMed ID 27780738   
OrganismHomo sapiens
Experiment descriptionNext-generation sequencing-based small RNA profiling of cerebrospinal fluid exosomes.
AuthorsYagi Y, Ohkubo T, Kawaji H, Machida A, Miyata H, Goda S, Roy S, Hayashizaki Y, Suzuki H, Yokota T.
Journal name Neurosci Lett.
Publication year2017
SampleSerum
Sample nameHealthy donor 1
Molecules identified in the studymiRNA
Methods used in the studyNext generation sequencing
EV-TRACK -
13
Experiment ID1204
Identified moleculemiRNA
Identification method Next generation sequencing
PubMed ID 27780738   
OrganismHomo sapiens
Experiment descriptionNext-generation sequencing-based small RNA profiling of cerebrospinal fluid exosomes.
AuthorsYagi Y, Ohkubo T, Kawaji H, Machida A, Miyata H, Goda S, Roy S, Hayashizaki Y, Suzuki H, Yokota T.
Journal name Neurosci Lett.
Publication year2017
SampleSerum
Sample nameHealthy donor 2
Molecules identified in the studymiRNA
Methods used in the studyNext generation sequencing
EV-TRACK -
14
Experiment ID1205
Identified moleculemiRNA
Identification method Next generation sequencing
PubMed ID 27780738   
OrganismHomo sapiens
Experiment descriptionNext-generation sequencing-based small RNA profiling of cerebrospinal fluid exosomes.
AuthorsYagi Y, Ohkubo T, Kawaji H, Machida A, Miyata H, Goda S, Roy S, Hayashizaki Y, Suzuki H, Yokota T.
Journal name Neurosci Lett.
Publication year2017
SampleSerum
Sample nameSerum
Molecules identified in the studymiRNA
Methods used in the studyNext generation sequencing
EV-TRACK -
15
Experiment ID3533
Identified moleculemiRNA
Identification method RNA sequencing
PubMed ID Unpublished / Not applicable
OrganismHomo sapiens
Experiment descriptionSmall RNA Sequencing of Circulating Small Extracellular Vesicle MicroRNAs in Patients with Amyotrophic Lateral Sclerosis
AuthorsKim JA, Park C, Sung JJ, Choi SJ, Hong YH
Journal name Not applicable
Publication year0
SampleSerum
Sample nameSerum
Molecules identified in the studymiRNA
Methods used in the studyRNA sequencing
EV-TRACK -
16
Experiment ID1177
Identified moleculemiRNA
Identification method RNA sequencing
PubMed ID 29854963   
OrganismHomo sapiens
Experiment descriptionGenome-wide Profiling of Urinary Extracellular Vesicle microRNAs Associated With Diabetic Nephropathy in Type 1 Diabetes.
AuthorsGhai V, Wu X, Bheda-Malge A, Argyropoulos CP, Bernardo JF, Orchard T, Galas D, Wang K.
Journal name Kidney Int Rep.
Publication year2017
SampleUrine
Sample namePersistent patient
Molecules identified in the studymiRNA
Methods used in the studyRNA sequencing
qPCR
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17
Experiment ID1178
Identified moleculemiRNA
Identification method RNA sequencing
PubMed ID 29854963   
OrganismHomo sapiens
Experiment descriptionGenome-wide Profiling of Urinary Extracellular Vesicle microRNAs Associated With Diabetic Nephropathy in Type 1 Diabetes.
AuthorsGhai V, Wu X, Bheda-Malge A, Argyropoulos CP, Bernardo JF, Orchard T, Galas D, Wang K.
Journal name Kidney Int Rep.
Publication year2017
SampleUrine
Sample nameIntermittent patient
Molecules identified in the studymiRNA
Methods used in the studyRNA sequencing
qPCR
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