miRNA description for let-7b-5p
miRNA accession let-7b-5p
Species Mus musculus
 let-7b-5p identified in exosomes derived from the following tissue/cell type
Colon cancer cells [Microvesicles] 34931471   
Mesenchymal stem cells [Small extracellular vesicles] 36260670   
Mesenchymal stem cells [Exosomes] 36253358   
Plasma [Small extracellular vesicles] 36260670   
 Experiment description of studies that identified let-7b-5p in exosomes
1
Experiment ID3375
Identified moleculemiRNA
Identification method Small RNA sequencing
PubMed ID 34931471   
OrganismMus musculus
Experiment descriptionExtracellular vesicles derived from tumour cells as a trigger of energy crisis in the skeletal muscle
AuthorsPin F, Beltrà M, Garcia-Castillo L, Pardini B, Birolo G, Matullo G, Penna F, Guttridge D, Costelli P.
Journal name J Cachexia Sarcopenia Muscle
Publication year2022
SampleColon cancer cells
Sample nameC26
Molecules identified in the studymiRNA
Methods used in the studySmall RNA sequencing
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2
Experiment ID1897
Identified moleculemiRNA
Identification method miRNA array
PubMed ID 36260670   
OrganismMus musculus
Experiment descriptionSmall extracellular vesicles from young adipose-derived stem cells prevent frailty, improve health span, and decrease epigenetic age in old mice
AuthorsSanz-Ros J, Romero-García N, Mas-Bargues C, Monleón D, Gordevicius J, Brooke RT, Dromant M, Díaz A, Derevyanko A, Guío-Carrión A, Román-Domínguez A, Inglés M, Blasco MA, Horvath S, Viña J, Borrás C.
Journal name Sci Adv
Publication year2022
SampleMesenchymal stem cells
Sample nameAdipose MSCs from old C57BL/6J mice
Molecules identified in the studymiRNA
Methods used in the studymiRNA array
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3
Experiment ID1922
Identified moleculemiRNA
Identification method miRNA sequencing
PubMed ID 36253358   
OrganismMus musculus
Experiment descriptionBone marrow mesenchymal stem cell-derived exosomal miR-21a-5p alleviates renal fibrosis by attenuating glycolysis by targeting PFKM
AuthorsXu S, Cheuk YC, Jia Y, Chen T, Chen J, Luo Y, Cao Y, Guo J, Dong L, Zhang Y, Shi Y, Rong R.
Journal name Cell Death Dis
Publication year2022
SampleMesenchymal stem cells
Sample nameBone marrow-derived MSCs
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
miRNA sequencing
qPCR
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4
Experiment ID1898
Identified moleculemiRNA
Identification method miRNA array
PubMed ID 36260670   
OrganismMus musculus
Experiment descriptionSmall extracellular vesicles from young adipose-derived stem cells prevent frailty, improve health span, and decrease epigenetic age in old mice
AuthorsSanz-Ros J, Romero-García N, Mas-Bargues C, Monleón D, Gordevicius J, Brooke RT, Dromant M, Díaz A, Derevyanko A, Guío-Carrión A, Román-Domínguez A, Inglés M, Blasco MA, Horvath S, Viña J, Borrás C.
Journal name Sci Adv
Publication year2022
SamplePlasma
Sample nameOld C57BL/6J mice
Molecules identified in the studymiRNA
Methods used in the studymiRNA array
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