miRNA description for let-7d |
miRNA accession |
let-7d |
Species |
Homo sapiens |
let-7d identified in exosomes derived from the following tissue/cell type |
Breast cancer cells [Exosomes]
|
20976003
|
Breast cancer cells [Extracellular vesicles]
|
24468161
|
Breast cancer cells [Extracellular vesicles]
|
24468161
|
Dendritic cells [Exosomes]
|
21505438
|
Lung cells [Microvesicles]
|
20079801
|
Serum [Exosomes]
|
18589210
|
Serum [Exosomes]
|
35173168
|
Serum [Exosomes]
|
35173168
|
Stomach cancer cells [Exosomes]
|
20949044
|
Stomach cancer cells [Exosomes]
|
20949044
|
T cells [Exosomes]
|
21505438
|
Experiment description of studies that identified let-7d in exosomes |
1
|
Experiment ID | 333 |
Identified molecule | miRNA
|
Identification method | Microarray
|
PubMed ID |
20976003
|
Organism | Homo sapiens |
Experiment description | Selective release of microRNA species from normal and malignant mammary epithelial cells |
Authors | Pigati L, Yaddanapudi SC, Iyengar R, Kim DJ, Hearn SA, Danforth D, Hastings ML, Duelli DM |
Journal name |
PLoS One
|
Publication year | 2010 |
Sample | Breast cancer cells |
Sample name | MCF-7 |
Molecules identified in the study | Protein miRNA |
Methods used in the study | Slot blot RT-PCR Microarray |
EV-TRACK |
-
|
|
|
2
|
Experiment ID | 1254 |
Identified molecule | miRNA
|
Identification method | Microarray
|
PubMed ID |
24468161
|
Organism | Homo sapiens |
Experiment description | Molecular characterization of exosome-like vesicles from breast cancer cells. |
Authors | Kruger S, Abd Elmageed ZY, Hawke DH, Wör PM, Jansen DA, Abdel-Mageed AB, Alt EU, Izadpanah R. |
Journal name |
BMC Cancer.
|
Publication year | 2014 |
Sample | Breast cancer cells |
Sample name | MCF7 |
Molecules identified in the study | Protein miRNA |
Methods used in the study | Mass spectrometry Microarray RT-PCR Western blotting |
EV-TRACK |
EV140357: EV-METRIC:22%
|
|
|
3
|
Experiment ID | 1255 |
Identified molecule | miRNA
|
Identification method | Microarray
|
PubMed ID |
24468161
|
Organism | Homo sapiens |
Experiment description | Molecular characterization of exosome-like vesicles from breast cancer cells. |
Authors | Kruger S, Abd Elmageed ZY, Hawke DH, Wör PM, Jansen DA, Abdel-Mageed AB, Alt EU, Izadpanah R. |
Journal name |
BMC Cancer.
|
Publication year | 2014 |
Sample | Breast cancer cells |
Sample name | MDA-MB231 |
Molecules identified in the study | Protein miRNA |
Methods used in the study | Mass spectrometry Microarray RT-PCR Western blotting |
EV-TRACK |
EV140357: EV-METRIC:22%
|
|
|
4
|
Experiment ID | 117 |
Identified molecule | miRNA
|
Identification method | Human miRNA Microarray Kit
|
PubMed ID |
21505438
|
Organism | Homo sapiens |
Experiment description | Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells. |
Authors | Mittelbrunn M, Gutiéez-Váuez C, Villarroya-Beltri C, Gonzáz S, Sáhez-Cabo F, Gonzáz MÁ Bernad A, Sáhez-Madrid F. |
Journal name |
NATCOM
|
Publication year | 2011 |
Sample | Dendritic cells |
Sample name | Dendritic cells |
Molecules identified in the study | Protein miRNA |
Methods used in the study | Mass spectrometry Microarray |
EV-TRACK |
EV110049: EV-METRIC:11%
|
|
|
5
|
Experiment ID | 324 |
Identified molecule | miRNA
|
Identification method | Microarray or RT-PCR
|
PubMed ID |
20079801
|
Organism | Mus musculus |
Experiment description | Microvesicle entry into marrow cells mediates tissue-specific changes in mRNA by direct delivery of mRNA and induction of transcription |
Authors | Aliotta JM, Pereira M, Johnson KW, de Paz N, Dooner MS, Puente N, Ayala C, Brilliant K, Berz D, Lee D, Ramratnam B, McMillan PN, Hixson DC, Josic D, Quesenberry PJ |
Journal name |
Exp Hematol
|
Publication year | 2010 |
Sample | Lung cells |
Sample name | Lung cells |
Molecules identified in the study | Protein miRNA |
Methods used in the study | FACS RT-PCR |
EV-TRACK |
EV100071: EV-METRIC:14%
|
|
|
6
|
Experiment ID | 45 |
Identified molecule | miRNA
|
Identification method | 467microRNA Array
|
PubMed ID |
18589210
|
Organism | Homo sapiens |
Experiment description | MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer. |
Authors | Taylor DD, Gercel-Taylor C |
Journal name |
GO
|
Publication year | 2008 |
Sample | Serum |
Sample name | Serum - Papillary adenocarcinoma of ovary |
Molecules identified in the study | Protein miRNA |
Methods used in the study | Western blotting MicroRNA array |
EV-TRACK |
-
|
|
|
7
|
Experiment ID | 2749 |
Identified molecule | miRNA
|
Identification method | qRT-PCR
|
PubMed ID |
35173168
|
Organism | Homo sapiens |
Experiment description | Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression |
Authors | Qi M, Xia Y, Wu Y, Zhang Z, Wang X, Lu L, Dai C, Song Y, Xu K, Ji W, Zhan L. |
Journal name |
Nat Commun
|
Publication year | 2022 |
Sample | Serum |
Sample name | Healthy |
Molecules identified in the study | miRNA |
Methods used in the study | qRT-PCR |
EV-TRACK |
-
|
|
|
8
|
Experiment ID | 2750 |
Identified molecule | miRNA
|
Identification method | qRT-PCR
|
PubMed ID |
35173168
|
Organism | Homo sapiens |
Experiment description | Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression |
Authors | Qi M, Xia Y, Wu Y, Zhang Z, Wang X, Lu L, Dai C, Song Y, Xu K, Ji W, Zhan L. |
Journal name |
Nat Commun
|
Publication year | 2022 |
Sample | Serum |
Sample name | Breast cancer patients |
Molecules identified in the study | miRNA |
Methods used in the study | qRT-PCR |
EV-TRACK |
-
|
|
|
9
|
Experiment ID | 88 |
Identified molecule | miRNA
|
Identification method | Human miRNA Microarray Kit RT-PCR
|
PubMed ID |
20949044
|
Organism | Homo sapiens |
Experiment description | Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line |
Authors | Ohshima K, Inoue K, Fujiwara A, Hatakeyama K, Kanto K, Watanabe Y, Muramatsu K, Fukuda Y, Ogura S, Yamaguchi K, Mochizuki T. |
Journal name |
PLOS1
|
Publication year | 2010 |
Sample | Stomach cancer cells |
Sample name | AZ-P7a |
Molecules identified in the study | Protein miRNA |
Methods used in the study | Immunoelectron microscopy Western blotting RT-PCR Human miRNA Microarray Kit |
EV-TRACK |
EV100005: EV-METRIC:44%
|
|
|
10
|
Experiment ID | 82 |
Identified molecule | miRNA
|
Identification method | RT-PCR
|
PubMed ID |
20949044
|
Organism | Homo sapiens |
Experiment description | Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line |
Authors | Ohshima K, Inoue K, Fujiwara A, Hatakeyama K, Kanto K, Watanabe Y, Muramatsu K, Fukuda Y, Ogura S, Yamaguchi K, Mochizuki T. |
Journal name |
PLOS1
|
Publication year | 2010 |
Sample | Stomach cancer cells |
Sample name | AZ-521 |
Molecules identified in the study | Protein miRNA |
Methods used in the study | Western blotting RT-PCR Human miRNA Microarray Kit |
EV-TRACK |
EV100005: EV-METRIC:44%
|
|
|
11
|
Experiment ID | 115 |
Identified molecule | miRNA
|
Identification method | Human miRNA Microarray Kit
|
PubMed ID |
21505438
|
Organism | Homo sapiens |
Experiment description | Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells. |
Authors | Mittelbrunn M, Gutiéez-Váuez C, Villarroya-Beltri C, Gonzáz S, Sáhez-Cabo F, Gonzáz MÁ Bernad A, Sáhez-Madrid F. |
Journal name |
NATCOM
|
Publication year | 2011 |
Sample | T cells |
Sample name | J77 |
Molecules identified in the study | Protein miRNA |
Methods used in the study | Mass spectrometry Microarray |
EV-TRACK |
EV110049: EV-METRIC:11%
|
|
|