miRNA description for miR-146b-5p |
| miRNA accession |
miR-146b-5p |
| Species |
Homo sapiens |
miR-146b-5p identified in exosomes derived from the following tissue/cell type |
|
Colorectal cancer cells [Exosomes]
|
33368224
|
|
Dendritic cells [Exosomes]
|
21505438
|
|
Intestinal epithelial cells [Exosomes]
|
33368224
|
|
Plasma [Extracellular vesicles/Exosomes]
|
31762962
|
|
Plasma [Extracellular vesicles/Exosomes]
|
31762962
|
|
Plasma [Extracellular vesicles/Exosomes]
|
31762962
|
|
T cells [Exosomes]
|
21505438
|
|
Urine [Exosomes]
|
24352158
|
Experiment description of studies that identified miR-146b-5p in exosomes |
| 1
|
| Experiment ID | 1334 |
| Identified molecule | miRNA
|
| Identification method | RT-PCR
|
| PubMed ID |
33368224
|
| Organism | Homo sapiens |
| Experiment description | Colorectal cancer prompted adipose tissue browning and cancer cachexia through transferring exosomal miR-146b-5p |
| Authors | Di W, Zhang W, Zhu B, Li X, Tang Q, Zhou Y. |
| Journal name |
J Cell Physiol
|
| Publication year | 2020 |
| Sample | Colorectal cancer cells |
| Sample name | HCT116 |
| Molecules identified in the study | Protein mRNA |
| Methods used in the study | Western blotting RT-PCT |
| EV-TRACK |
-
|
|
|
| 2
|
| Experiment ID | 117 |
| Identified molecule | miRNA
|
| Identification method | Human miRNA Microarray Kit
|
| PubMed ID |
21505438
|
| Organism | Homo sapiens |
| Experiment description | Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells. |
| Authors | Mittelbrunn M, Gutiéez-Váuez C, Villarroya-Beltri C, Gonzáz S, Sáhez-Cabo F, Gonzáz MÁ Bernad A, Sáhez-Madrid F. |
| Journal name |
NATCOM
|
| Publication year | 2011 |
| Sample | Dendritic cells |
| Sample name | Dendritic cells |
| Molecules identified in the study | Protein miRNA |
| Methods used in the study | Mass spectrometry Microarray |
| EV-TRACK |
EV110049: EV-METRIC:11%
|
|
|
| 3
|
| Experiment ID | 1333 |
| Identified molecule | miRNA
|
| Identification method | RT-PCR
|
| PubMed ID |
33368224
|
| Organism | Homo sapiens |
| Experiment description | Colorectal cancer prompted adipose tissue browning and cancer cachexia through transferring exosomal miR-146b-5p |
| Authors | Di W, Zhang W, Zhu B, Li X, Tang Q, Zhou Y. |
| Journal name |
J Cell Physiol
|
| Publication year | 2020 |
| Sample | Intestinal epithelial cells |
| Sample name | FHs 74 Int |
| Molecules identified in the study | Protein mRNA |
| Methods used in the study | Western blotting RT-PCT |
| EV-TRACK |
-
|
|
|
| 4
|
| Experiment ID | 2317 |
| Identified molecule | miRNA
|
| Identification method | Small RNA sequencing
|
| PubMed ID |
31762962
|
| Organism | Homo sapiens |
| Experiment description | Small RNA-sequence analysis of plasma-derived extracellular vesicle miRNAs in smokers and patients with chronic obstructive pulmonary disease as circulating biomarkers |
| Authors | Sundar IK, Li D, Rahman I. |
| Journal name |
J Extracell Vesicles
|
| Publication year | 2019 |
| Sample | Plasma |
| Sample name | Non-smokers |
| Molecules identified in the study | Protein small RNA |
| Methods used in the study | Western blotting Small RNA sequencing |
| EV-TRACK |
-
|
|
|
| 5
|
| Experiment ID | 2318 |
| Identified molecule | miRNA
|
| Identification method | Small RNA sequencing
|
| PubMed ID |
31762962
|
| Organism | Homo sapiens |
| Experiment description | Small RNA-sequence analysis of plasma-derived extracellular vesicle miRNAs in smokers and patients with chronic obstructive pulmonary disease as circulating biomarkers |
| Authors | Sundar IK, Li D, Rahman I. |
| Journal name |
J Extracell Vesicles
|
| Publication year | 2019 |
| Sample | Plasma |
| Sample name | Smokers |
| Molecules identified in the study | Protein small RNA |
| Methods used in the study | Western blotting Small RNA sequencing |
| EV-TRACK |
-
|
|
|
| 6
|
| Experiment ID | 2319 |
| Identified molecule | miRNA
|
| Identification method | Small RNA sequencing
|
| PubMed ID |
31762962
|
| Organism | Homo sapiens |
| Experiment description | Small RNA-sequence analysis of plasma-derived extracellular vesicle miRNAs in smokers and patients with chronic obstructive pulmonary disease as circulating biomarkers |
| Authors | Sundar IK, Li D, Rahman I. |
| Journal name |
J Extracell Vesicles
|
| Publication year | 2019 |
| Sample | Plasma |
| Sample name | COPD patients |
| Molecules identified in the study | Protein small RNA |
| Methods used in the study | Western blotting Small RNA sequencing |
| EV-TRACK |
-
|
|
|
| 7
|
| Experiment ID | 115 |
| Identified molecule | miRNA
|
| Identification method | Human miRNA Microarray Kit
|
| PubMed ID |
21505438
|
| Organism | Homo sapiens |
| Experiment description | Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells. |
| Authors | Mittelbrunn M, Gutiéez-Váuez C, Villarroya-Beltri C, Gonzáz S, Sáhez-Cabo F, Gonzáz MÁ Bernad A, Sáhez-Madrid F. |
| Journal name |
NATCOM
|
| Publication year | 2011 |
| Sample | T cells |
| Sample name | J77 |
| Molecules identified in the study | Protein miRNA |
| Methods used in the study | Mass spectrometry Microarray |
| EV-TRACK |
EV110049: EV-METRIC:11%
|
|
|
| 8
|
| Experiment ID | 357 |
| Identified molecule | miRNA
|
| Identification method | RNA deep sequencing
|
| PubMed ID |
24352158
|
| Organism | Homo sapiens |
| Experiment description | Characterization and deep sequencing analysis of exosomal miRNA in human urine |
| Authors | Lesley Cheng, Xin Sun, Bradley M. Coleman, Andrew F. Hill |
| Journal name |
Kidney Int
|
| Publication year | 2014 |
| Sample | Urine |
| Sample name | Urine - Normal |
| Molecules identified in the study | miRNA |
| Methods used in the study | RNA deep sequencing |
| EV-TRACK |
EV140147: EV-METRIC:44%, 0%, 22%
|
|
|