miRNA description for miR-16
miRNA accession miR-16
Species Homo sapiens
 miR-16 identified in exosomes derived from the following tissue/cell type
Adipocytes [Microvesicles] 21435393   
Adipocytes [Microvesicles] 21435393   
Adipocytes [Microvesicles] 21435393   
Breast cancer cells [Exosomes] 20976003   
Breast cancer cells [Exosomes] 20976003   
Breast cancer cells [Exosomes] 20976003   
Breast cancer cells [Exosomes] 20976003   
Breast cancer cells [Exosomes] 20976003   
Breast cancer cells [Extracellular vesicles] 24468161   
Breast cancer cells [Extracellular vesicles] 24468161   
Dendritic cells [Exosomes] 21505438   
Embryonic stem cells [Microvesicles] 19266099   
Epithelial cells [Microvesicles] 20615901   
Epithelial cells [Exosomes] 20615901   
Glioblastoma cells [Microvesicles] 19011622   
Liver stem cells [Microvesicles] 20668554   
Lung cancer cells [Microvesicles] 20615901   
Lung cancer cells [Exosomes] 20615901   
Mesenchymal stem cells [Microvesicles] 20668554   
Serum [Exosomes] 18589210   
Serum [Microvesicles] 21435393   
T cells [Exosomes] 21505438   
 Experiment description of studies that identified miR-16 in exosomes
1
Experiment ID206
Identified moleculemiRNA
Identification method RT-PCR
PubMed ID 21435393   
OrganismRattus norvegicus
Experiment descriptionMicrovesicles released from rat adipocytes and harboring glycosylphosphatidylinositol-anchored proteins transfer RNA stimulating lipid synthesis
AuthorsMüG, Schneider M, Biemer-Daub G, Wied S.
Journal name Cell Signal
Publication year2011
SampleAdipocytes
Sample nameAdipocytes - Large
Molecules identified in the studymRNA
miRNA
Methods used in the studyRT-PCR
EV-TRACK EV110050: EV-METRIC:43%, 29%
2
Experiment ID207
Identified moleculemiRNA
Identification method RT-PCR
PubMed ID 21435393   
OrganismRattus norvegicus
Experiment descriptionMicrovesicles released from rat adipocytes and harboring glycosylphosphatidylinositol-anchored proteins transfer RNA stimulating lipid synthesis
AuthorsMüG, Schneider M, Biemer-Daub G, Wied S.
Journal name Cell Signal
Publication year2011
SampleAdipocytes
Sample nameStromal vascular cells - Differentiated adipocytes
Molecules identified in the studymRNA
miRNA
Methods used in the studyRT-PCR
EV-TRACK EV110050: EV-METRIC:43%, 29%
3
Experiment ID209
Identified moleculemiRNA
Identification method RT-PCR
PubMed ID 21435393   
OrganismRattus norvegicus
Experiment descriptionMicrovesicles released from rat adipocytes and harboring glycosylphosphatidylinositol-anchored proteins transfer RNA stimulating lipid synthesis
AuthorsMüG, Schneider M, Biemer-Daub G, Wied S.
Journal name Cell Signal
Publication year2011
SampleAdipocytes
Sample nameAdipocytes - Small
Molecules identified in the studymRNA
miRNA
Methods used in the studyRT-PCR
EV-TRACK EV110050: EV-METRIC:43%, 29%
4
Experiment ID334
Identified moleculemiRNA
Identification method RT-PCR
PubMed ID 20976003   
OrganismHomo sapiens
Experiment descriptionSelective release of microRNA species from normal and malignant mammary epithelial cells
AuthorsPigati L, Yaddanapudi SC, Iyengar R, Kim DJ, Hearn SA, Danforth D, Hastings ML, Duelli DM
Journal name PLoS One
Publication year2010
SampleBreast cancer cells
Sample nameMDA-MB-231
Molecules identified in the studyProtein
miRNA
Methods used in the studySlot blot
RT-PCR
EV-TRACK -
5
Experiment ID335
Identified moleculemiRNA
Identification method RT-PCR
PubMed ID 20976003   
OrganismHomo sapiens
Experiment descriptionSelective release of microRNA species from normal and malignant mammary epithelial cells
AuthorsPigati L, Yaddanapudi SC, Iyengar R, Kim DJ, Hearn SA, Danforth D, Hastings ML, Duelli DM
Journal name PLoS One
Publication year2010
SampleBreast cancer cells
Sample nameBT-20
Molecules identified in the studyProtein
miRNA
Methods used in the studySlot blot
RT-PCR
EV-TRACK -
6
Experiment ID336
Identified moleculemiRNA
Identification method RT-PCR
PubMed ID 20976003   
OrganismHomo sapiens
Experiment descriptionSelective release of microRNA species from normal and malignant mammary epithelial cells
AuthorsPigati L, Yaddanapudi SC, Iyengar R, Kim DJ, Hearn SA, Danforth D, Hastings ML, Duelli DM
Journal name PLoS One
Publication year2010
SampleBreast cancer cells
Sample nameMCF 10A
Molecules identified in the studyProtein
miRNA
Methods used in the studySlot blot
RT-PCR
EV-TRACK -
7
Experiment ID337
Identified moleculemiRNA
Identification method RT-PCR
PubMed ID 20976003   
OrganismHomo sapiens
Experiment descriptionSelective release of microRNA species from normal and malignant mammary epithelial cells
AuthorsPigati L, Yaddanapudi SC, Iyengar R, Kim DJ, Hearn SA, Danforth D, Hastings ML, Duelli DM
Journal name PLoS One
Publication year2010
SampleBreast cancer cells
Sample nameSK-BR-3
Molecules identified in the studymiRNA
Methods used in the studyRT-PCR
EV-TRACK -
8
Experiment ID333
Identified moleculemiRNA
Identification method Microarray
RT-PCR
PubMed ID 20976003   
OrganismHomo sapiens
Experiment descriptionSelective release of microRNA species from normal and malignant mammary epithelial cells
AuthorsPigati L, Yaddanapudi SC, Iyengar R, Kim DJ, Hearn SA, Danforth D, Hastings ML, Duelli DM
Journal name PLoS One
Publication year2010
SampleBreast cancer cells
Sample nameMCF-7
Molecules identified in the studyProtein
miRNA
Methods used in the studySlot blot
RT-PCR
Microarray
EV-TRACK -
9
Experiment ID1254
Identified moleculemiRNA
Identification method Microarray
PubMed ID 24468161   
OrganismHomo sapiens
Experiment descriptionMolecular characterization of exosome-like vesicles from breast cancer cells.
AuthorsKruger S, Abd Elmageed ZY, Hawke DH, Wör PM, Jansen DA, Abdel-Mageed AB, Alt EU, Izadpanah R.
Journal name BMC Cancer.
Publication year2014
SampleBreast cancer cells
Sample nameMCF7
Molecules identified in the studyProtein
miRNA
Methods used in the studyMass spectrometry
Microarray
RT-PCR
Western blotting
EV-TRACK EV140357: EV-METRIC:22%
10
Experiment ID1255
Identified moleculemiRNA
Identification method Microarray
PubMed ID 24468161   
OrganismHomo sapiens
Experiment descriptionMolecular characterization of exosome-like vesicles from breast cancer cells.
AuthorsKruger S, Abd Elmageed ZY, Hawke DH, Wör PM, Jansen DA, Abdel-Mageed AB, Alt EU, Izadpanah R.
Journal name BMC Cancer.
Publication year2014
SampleBreast cancer cells
Sample nameMDA-MB231
Molecules identified in the studyProtein
miRNA
Methods used in the studyMass spectrometry
Microarray
RT-PCR
Western blotting
EV-TRACK EV140357: EV-METRIC:22%
11
Experiment ID117
Identified moleculemiRNA
Identification method Human miRNA Microarray Kit
PubMed ID 21505438   
OrganismHomo sapiens
Experiment descriptionUnidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells.
AuthorsMittelbrunn M, Gutiéez-Váuez C, Villarroya-Beltri C, Gonzáz S, Sáhez-Cabo F, Gonzáz MÁ Bernad A, Sáhez-Madrid F.
Journal name NATCOM
Publication year2011
SampleDendritic cells
Sample nameDendritic cells
Molecules identified in the studyProtein
miRNA
Methods used in the studyMass spectrometry
Microarray
EV-TRACK EV110049: EV-METRIC:11%
12
Experiment ID317
Identified moleculemiRNA
Identification method RT-PCR
PubMed ID 19266099   
OrganismHomo sapiens
Experiment descriptionTransfer of microRNAs by embryonic stem cell microvesicles
AuthorsYuan A, Farber EL, Rapoport AL, Tejada D, Deniskin R, Akhmedov NB, Farber DB
Journal name PLoS One
Publication year2009
SampleEmbryonic stem cells
Sample nameEmbryonic stem cells
Molecules identified in the studymRNA
miRNA
snRNA
Methods used in the studyRT-PCR
EV-TRACK -
13
Experiment ID320
Identified moleculemiRNA
Identification method RT-PCR
PubMed ID 20615901   
OrganismHomo sapiens
Experiment descriptionExport of microRNAs and microRNA-protective protein by mammalian cells
AuthorsWang K, Zhang S, Weber J, Baxter D, Galas DJ
Journal name Nucleic Acids Res
Publication year2010
SampleEpithelial cells
Sample nameA549
Molecules identified in the studymiRNA
Methods used in the studyRT-PCR
EV-TRACK EV100093: EV-METRIC:0%
14
Experiment ID341
Identified moleculemiRNA
Identification method RT-PCR
PubMed ID 20615901   
OrganismHomo sapiens
Experiment descriptionExport of microRNAs and microRNA-protective protein by mammalian cells
AuthorsWang K, Zhang S, Weber J, Baxter D, Galas DJ
Journal name Nucleic Acids Res
Publication year2010
SampleEpithelial cells
Sample nameA549
Molecules identified in the studymiRNA
Methods used in the studyRT-PCR
EV-TRACK EV100093: EV-METRIC:0%
15
Experiment ID203
Identified moleculemiRNA
Identification method RT-PCR
PubMed ID 19011622   
OrganismHomo sapiens
Experiment descriptionGlioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers
AuthorsSkog J, Wüer T, van Rijn S, Meijer DH, Gainche L, Sena-Esteves M, Curry WT Jr, Carter BS, Krichevsky AM, Breakefield XO
Journal name Nat Cell Biol
Publication year2008
SampleGlioblastoma cells
Sample nameGlioblastoma cells
Molecules identified in the studyProtein
miRNA
mRNA
Methods used in the studyRT-PCR
Antibody array
Microarray
EV-TRACK -
16
Experiment ID182
Identified moleculemiRNA
Identification method RT-PCR
PubMed ID 20668554   
OrganismHomo sapiens
Experiment descriptionMicrovesicles derived from adult human bone marrow and tissue specific mesenchymal stem cells shuttle selected pattern of miRNAs
AuthorsCollino F, Deregibus MC, Bruno S, Sterpone L, Aghemo G, Viltono L, Tetta C, Camussi G.
Journal name PLoS One
Publication year2010
SampleLiver stem cells
Sample nameLiver stem cells - Normal
Molecules identified in the studymiRNA
Methods used in the studyWestern blotting
RT-PCR
Immunogold
Immunoelectron microscopy
EV-TRACK -
17
Experiment ID319
Identified moleculemiRNA
Identification method RT-PCR
PubMed ID 20615901   
OrganismHomo sapiens
Experiment descriptionExport of microRNAs and microRNA-protective protein by mammalian cells
AuthorsWang K, Zhang S, Weber J, Baxter D, Galas DJ
Journal name Nucleic Acids Res
Publication year2010
SampleLung cancer cells
Sample nameHepG2
Molecules identified in the studymiRNA
Methods used in the studyRT-PCR
EV-TRACK EV100093: EV-METRIC:0%
18
Experiment ID340
Identified moleculemiRNA
Identification method RT-PCR
PubMed ID 20615901   
OrganismHomo sapiens
Experiment descriptionExport of microRNAs and microRNA-protective protein by mammalian cells
AuthorsWang K, Zhang S, Weber J, Baxter D, Galas DJ
Journal name Nucleic Acids Res
Publication year2010
SampleLung cancer cells
Sample nameHepG2
Molecules identified in the studymiRNA
Methods used in the studyRT-PCR
EV-TRACK EV100093: EV-METRIC:0%
19
Experiment ID181
Identified moleculemiRNA
Identification method RT-PCR
PubMed ID 20668554   
OrganismHomo sapiens
Experiment descriptionMicrovesicles derived from adult human bone marrow and tissue specific mesenchymal stem cells shuttle selected pattern of miRNAs
AuthorsCollino F, Deregibus MC, Bruno S, Sterpone L, Aghemo G, Viltono L, Tetta C, Camussi G.
Journal name PLoS One
Publication year2010
SampleMesenchymal stem cells
Sample nameMesenchymal stem cells - Normal
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
RT-PCR
Immunogold
Immunoelectron microscopy
EV-TRACK -
20
Experiment ID45
Identified moleculemiRNA
Identification method 467microRNA Array
PubMed ID 18589210   
OrganismHomo sapiens
Experiment descriptionMicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer.
AuthorsTaylor DD, Gercel-Taylor C
Journal name GO
Publication year2008
SampleSerum
Sample nameSerum - Papillary adenocarcinoma of ovary
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
MicroRNA array
EV-TRACK -
21
Experiment ID208
Identified moleculemiRNA
Identification method RT-PCR
PubMed ID 21435393   
OrganismRattus norvegicus
Experiment descriptionMicrovesicles released from rat adipocytes and harboring glycosylphosphatidylinositol-anchored proteins transfer RNA stimulating lipid synthesis
AuthorsMüG, Schneider M, Biemer-Daub G, Wied S.
Journal name Cell Signal
Publication year2011
SampleSerum
Sample nameSerum - Normal
Molecules identified in the studymRNA
miRNA
Methods used in the studyRT-PCR
EV-TRACK EV110050: EV-METRIC:43%, 29%
22
Experiment ID115
Identified moleculemiRNA
Identification method Human miRNA Microarray Kit
PubMed ID 21505438   
OrganismHomo sapiens
Experiment descriptionUnidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells.
AuthorsMittelbrunn M, Gutiéez-Váuez C, Villarroya-Beltri C, Gonzáz S, Sáhez-Cabo F, Gonzáz MÁ Bernad A, Sáhez-Madrid F.
Journal name NATCOM
Publication year2011
SampleT cells
Sample nameJ77
Molecules identified in the studyProtein
miRNA
Methods used in the studyMass spectrometry
Microarray
EV-TRACK EV110049: EV-METRIC:11%