miRNA description for miR-21
miRNA accession miR-21
Species Homo sapiens
 miR-21 identified in exosomes derived from the following tissue/cell type
Ascites [Exosomes] 21601258   
Ascites [Exosomes] 21601258   
Breast cancer cells [Exosomes] 20976003   
Breast cancer cells [Exosomes] 20976003   
Breast cancer cells [Exosomes] 20976003   
Breast cancer cells [Exosomes] 20976003   
Breast cancer cells [Exosomes] 20976003   
Bronchoalveolar lavage fluid [Exosomes] 29956871   
Bronchoalveolar lavage fluid [Microvesicles] 29956871   
Bronchoalveolar lavage fluid [Exosomes] 29956871   
Bronchoalveolar lavage fluid [Microvesicles] 29956871   
Dendritic cells [Exosomes] 21505438   
Embryonic stem cells [Microvesicles] 19266099   
Glioblastoma cells [Microvesicles] 19011622   
Liver stem cells [Microvesicles] 20668554   
Malignant pleural effusions [Exosomes] 21601258   
Mesenchymal stem cells [Microvesicles] 20668554   
Plasma [Exosomes] 19289371   
Serum [Exosomes] 18589210   
Serum [Microvesicles] 19011622   
Serum [Microvesicles] 19011622   
T cells [Exosomes] 21505438   
 Experiment description of studies that identified miR-21 in exosomes
1
Experiment ID108
Identified moleculemiRNA
Identification method RT-PCR
PubMed ID 21601258   
OrganismHomo sapiens
Experiment descriptionLoss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage.
AuthorsRupp AK, Rupp C, Keller S, Brase JC, Ehehalt R, Fogel M, Moldenhauer G, Marmé, Sün H, Altevogt P.
Journal name GO
Publication year2011
SampleAscites
Sample nameMalignant ascites - ovarian cancer
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
Immunoelectron microscopy
EV-TRACK EV110020: EV-METRIC:13%, 63%, 50%
2
Experiment ID110
Identified moleculemiRNA
Identification method RT-PCR
PubMed ID 21601258   
OrganismHomo sapiens
Experiment descriptionLoss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage.
AuthorsRupp AK, Rupp C, Keller S, Brase JC, Ehehalt R, Fogel M, Moldenhauer G, Marmé, Sün H, Altevogt P.
Journal name GO
Publication year2011
SampleAscites
Sample nameAscites - liver cirrhosis
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
Immunoelectron microscopy
EV-TRACK EV110020: EV-METRIC:13%, 63%, 50%
3
Experiment ID334
Identified moleculemiRNA
Identification method RT-PCR
PubMed ID 20976003   
OrganismHomo sapiens
Experiment descriptionSelective release of microRNA species from normal and malignant mammary epithelial cells
AuthorsPigati L, Yaddanapudi SC, Iyengar R, Kim DJ, Hearn SA, Danforth D, Hastings ML, Duelli DM
Journal name PLoS One
Publication year2010
SampleBreast cancer cells
Sample nameMDA-MB-231
Molecules identified in the studyProtein
miRNA
Methods used in the studySlot blot
RT-PCR
EV-TRACK -
4
Experiment ID335
Identified moleculemiRNA
Identification method RT-PCR
PubMed ID 20976003   
OrganismHomo sapiens
Experiment descriptionSelective release of microRNA species from normal and malignant mammary epithelial cells
AuthorsPigati L, Yaddanapudi SC, Iyengar R, Kim DJ, Hearn SA, Danforth D, Hastings ML, Duelli DM
Journal name PLoS One
Publication year2010
SampleBreast cancer cells
Sample nameBT-20
Molecules identified in the studyProtein
miRNA
Methods used in the studySlot blot
RT-PCR
EV-TRACK -
5
Experiment ID336
Identified moleculemiRNA
Identification method RT-PCR
PubMed ID 20976003   
OrganismHomo sapiens
Experiment descriptionSelective release of microRNA species from normal and malignant mammary epithelial cells
AuthorsPigati L, Yaddanapudi SC, Iyengar R, Kim DJ, Hearn SA, Danforth D, Hastings ML, Duelli DM
Journal name PLoS One
Publication year2010
SampleBreast cancer cells
Sample nameMCF 10A
Molecules identified in the studyProtein
miRNA
Methods used in the studySlot blot
RT-PCR
EV-TRACK -
6
Experiment ID337
Identified moleculemiRNA
Identification method RT-PCR
PubMed ID 20976003   
OrganismHomo sapiens
Experiment descriptionSelective release of microRNA species from normal and malignant mammary epithelial cells
AuthorsPigati L, Yaddanapudi SC, Iyengar R, Kim DJ, Hearn SA, Danforth D, Hastings ML, Duelli DM
Journal name PLoS One
Publication year2010
SampleBreast cancer cells
Sample nameSK-BR-3
Molecules identified in the studymiRNA
Methods used in the studyRT-PCR
EV-TRACK -
7
Experiment ID333
Identified moleculemiRNA
Identification method Microarray
RT-PCR
PubMed ID 20976003   
OrganismHomo sapiens
Experiment descriptionSelective release of microRNA species from normal and malignant mammary epithelial cells
AuthorsPigati L, Yaddanapudi SC, Iyengar R, Kim DJ, Hearn SA, Danforth D, Hastings ML, Duelli DM
Journal name PLoS One
Publication year2010
SampleBreast cancer cells
Sample nameMCF-7
Molecules identified in the studyProtein
miRNA
Methods used in the studySlot blot
RT-PCR
Microarray
EV-TRACK -
8
Experiment ID665
Identified moleculemiRNA
Identification method RT-PCR
qPCR
PubMed ID 29956871   
OrganismHomo sapiens
Experiment descriptionExpression analysis of extracellular microRNA in bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis
AuthorsKishore A, Navratilova Z, Kolek V, Novosadova E, .é K, du Bois RM, Petrek M.
Journal name Respirology
Publication year2018
SampleBronchoalveolar lavage fluid
Sample nameSarcoidosis patients- CXR.I
Molecules identified in the studymiRNA
Methods used in the studyRT-PCR
qPCR
EV-TRACK -
9
Experiment ID666
Identified moleculemiRNA
Identification method RT-PCR
qPCR
PubMed ID 29956871   
OrganismHomo sapiens
Experiment descriptionExpression analysis of extracellular microRNA in bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis
AuthorsKishore A, Navratilova Z, Kolek V, Novosadova E, .é K, du Bois RM, Petrek M.
Journal name Respirology
Publication year2018
SampleBronchoalveolar lavage fluid
Sample nameSarcoidosis patients- CXR.I
Molecules identified in the studymiRNA
Methods used in the studyRT-PCR
qPCR
EV-TRACK -
10
Experiment ID667
Identified moleculemiRNA
Identification method RT-PCR
qPCR
PubMed ID 29956871   
OrganismHomo sapiens
Experiment descriptionExpression analysis of extracellular microRNA in bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis
AuthorsKishore A, Navratilova Z, Kolek V, Novosadova E, .é K, du Bois RM, Petrek M.
Journal name Respirology
Publication year2018
SampleBronchoalveolar lavage fluid
Sample nameSarcoidosis patients- CXR.II
Molecules identified in the studymiRNA
Methods used in the studyRT-PCR
qPCR
EV-TRACK -
11
Experiment ID668
Identified moleculemiRNA
Identification method RT-PCR
qPCR
PubMed ID 29956871   
OrganismHomo sapiens
Experiment descriptionExpression analysis of extracellular microRNA in bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis
AuthorsKishore A, Navratilova Z, Kolek V, Novosadova E, .é K, du Bois RM, Petrek M.
Journal name Respirology
Publication year2018
SampleBronchoalveolar lavage fluid
Sample nameSarcoidosis patients- CXR.II
Molecules identified in the studymiRNA
Methods used in the studyRT-PCR
qPCR
EV-TRACK -
12
Experiment ID117
Identified moleculemiRNA
Identification method Human miRNA Microarray Kit
PubMed ID 21505438   
OrganismHomo sapiens
Experiment descriptionUnidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells.
AuthorsMittelbrunn M, Gutiéez-Váuez C, Villarroya-Beltri C, Gonzáz S, Sáhez-Cabo F, Gonzáz MÁ Bernad A, Sáhez-Madrid F.
Journal name NATCOM
Publication year2011
SampleDendritic cells
Sample nameDendritic cells
Molecules identified in the studyProtein
miRNA
Methods used in the studyMass spectrometry
Microarray
EV-TRACK EV110049: EV-METRIC:11%
13
Experiment ID317
Identified moleculemiRNA
Identification method RT-PCR
PubMed ID 19266099   
OrganismHomo sapiens
Experiment descriptionTransfer of microRNAs by embryonic stem cell microvesicles
AuthorsYuan A, Farber EL, Rapoport AL, Tejada D, Deniskin R, Akhmedov NB, Farber DB
Journal name PLoS One
Publication year2009
SampleEmbryonic stem cells
Sample nameEmbryonic stem cells
Molecules identified in the studymRNA
miRNA
snRNA
Methods used in the studyRT-PCR
EV-TRACK -
14
Experiment ID203
Identified moleculemiRNA
Identification method RT-PCR
PubMed ID 19011622   
OrganismHomo sapiens
Experiment descriptionGlioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers
AuthorsSkog J, Wüer T, van Rijn S, Meijer DH, Gainche L, Sena-Esteves M, Curry WT Jr, Carter BS, Krichevsky AM, Breakefield XO
Journal name Nat Cell Biol
Publication year2008
SampleGlioblastoma cells
Sample nameGlioblastoma cells
Molecules identified in the studyProtein
miRNA
mRNA
Methods used in the studyRT-PCR
Antibody array
Microarray
EV-TRACK -
15
Experiment ID182
Identified moleculemiRNA
Identification method RT-PCR
PubMed ID 20668554   
OrganismHomo sapiens
Experiment descriptionMicrovesicles derived from adult human bone marrow and tissue specific mesenchymal stem cells shuttle selected pattern of miRNAs
AuthorsCollino F, Deregibus MC, Bruno S, Sterpone L, Aghemo G, Viltono L, Tetta C, Camussi G.
Journal name PLoS One
Publication year2010
SampleLiver stem cells
Sample nameLiver stem cells - Normal
Molecules identified in the studymiRNA
Methods used in the studyWestern blotting
RT-PCR
Immunogold
Immunoelectron microscopy
EV-TRACK -
16
Experiment ID109
Identified moleculemiRNA
Identification method RT-PCR
PubMed ID 21601258   
OrganismHomo sapiens
Experiment descriptionLoss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage.
AuthorsRupp AK, Rupp C, Keller S, Brase JC, Ehehalt R, Fogel M, Moldenhauer G, Marmé, Sün H, Altevogt P.
Journal name GO
Publication year2011
SampleMalignant pleural effusions
Sample namePleural effusions - breast cancer
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
EV-TRACK EV110020: EV-METRIC:13%, 63%, 50%
17
Experiment ID181
Identified moleculemiRNA
Identification method RT-PCR
PubMed ID 20668554   
OrganismHomo sapiens
Experiment descriptionMicrovesicles derived from adult human bone marrow and tissue specific mesenchymal stem cells shuttle selected pattern of miRNAs
AuthorsCollino F, Deregibus MC, Bruno S, Sterpone L, Aghemo G, Viltono L, Tetta C, Camussi G.
Journal name PLoS One
Publication year2010
SampleMesenchymal stem cells
Sample nameMesenchymal stem cells - Normal
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
RT-PCR
Immunogold
Immunoelectron microscopy
EV-TRACK -
18
Experiment ID325
Identified moleculemiRNA
Identification method Microarray
PubMed ID 19289371   
OrganismHomo sapiens
Experiment descriptionExosomal microRNA: a diagnostic marker for lung cancer
AuthorsRabinowits G, Gerç-Taylor C, Day JM, Taylor DD, Kloecker GH
Journal name Clin Lung Cancer
Publication year2009
SamplePlasma
Sample namePlasma - Lung adenocarcinoma patients
Molecules identified in the studymiRNA
Methods used in the studyMicroarray
EV-TRACK -
19
Experiment ID45
Identified moleculemiRNA
Identification method 467microRNA Array
PubMed ID 18589210   
OrganismHomo sapiens
Experiment descriptionMicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer.
AuthorsTaylor DD, Gercel-Taylor C
Journal name GO
Publication year2008
SampleSerum
Sample nameSerum - Papillary adenocarcinoma of ovary
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
MicroRNA array
EV-TRACK -
20
Experiment ID204
Identified moleculemiRNA
Identification method RT-PCR
PubMed ID 19011622   
OrganismHomo sapiens
Experiment descriptionGlioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers
AuthorsSkog J, Wüer T, van Rijn S, Meijer DH, Gainche L, Sena-Esteves M, Curry WT Jr, Carter BS, Krichevsky AM, Breakefield XO
Journal name Nat Cell Biol
Publication year2008
SampleSerum
Sample nameSerum - Normal
Molecules identified in the studymRNA
miRNA
Methods used in the studyRT-PCR
EV-TRACK -
21
Experiment ID205
Identified moleculemiRNA
Identification method RT-PCR
PubMed ID 19011622   
OrganismHomo sapiens
Experiment descriptionGlioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers
AuthorsSkog J, Wüer T, van Rijn S, Meijer DH, Gainche L, Sena-Esteves M, Curry WT Jr, Carter BS, Krichevsky AM, Breakefield XO
Journal name Nat Cell Biol
Publication year2008
SampleSerum
Sample nameSerum - Glioblastoma
Molecules identified in the studymRNA
miRNA
Methods used in the studyRT-PCR
EV-TRACK -
22
Experiment ID115
Identified moleculemiRNA
Identification method Human miRNA Microarray Kit
PubMed ID 21505438   
OrganismHomo sapiens
Experiment descriptionUnidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells.
AuthorsMittelbrunn M, Gutiéez-Váuez C, Villarroya-Beltri C, Gonzáz S, Sáhez-Cabo F, Gonzáz MÁ Bernad A, Sáhez-Madrid F.
Journal name NATCOM
Publication year2011
SampleT cells
Sample nameJ77
Molecules identified in the studyProtein
miRNA
Methods used in the studyMass spectrometry
Microarray
EV-TRACK EV110049: EV-METRIC:11%