miRNA description for miR-21 |
| miRNA accession |
miR-21 |
| Species |
Mus musculus |
miR-21 identified in exosomes derived from the following tissue/cell type |
|
Embryonic kidney cells [Extracellular vesicles]
|
34315885
|
|
Embryonic kidney cells [Extracellular vesicles]
|
34315885
|
|
Kidney epithelial cells [Extracellular vesicles]
|
34315885
|
|
Kidney epithelial cells [Extracellular vesicles]
|
34315885
|
|
Mast cells [Exosomes]
|
17486113
|
|
Neuronal cells [Exosomes]
|
22965126
|
|
Neuronal cells [Exosomes]
|
22965126
|
|
Neuronal cells [Exosomes]
|
22965126
|
|
Neuronal cells [Exosomes]
|
22965126
|
|
Neuronal cells [Exosomes]
|
22965126
|
Experiment description of studies that identified miR-21 in exosomes |
| 1
|
| Experiment ID | 2525 |
| Identified molecule | miRNA
|
| Identification method | qRT-PCR
|
| PubMed ID |
34315885
|
| Organism | Mus musculus |
| Experiment description | Extracellular vesicles and exosomes generated from cystic renal epithelial cells promote cyst growth in autosomal dominant polycystic kidney disease |
| Authors | Ding H, Li LX, Harris PC, Yang J, Li X. |
| Journal name |
Nat Commun
|
| Publication year | 2021 |
| Sample | Embryonic kidney cells |
| Sample name | MEK - Pkd1 WT |
| Molecules identified in the study | Protein miRNA |
| Methods used in the study | Western blotting qRT-PCR |
| EV-TRACK |
-
|
|
|
| 2
|
| Experiment ID | 2526 |
| Identified molecule | miRNA
|
| Identification method | qRT-PCR
|
| PubMed ID |
34315885
|
| Organism | Mus musculus |
| Experiment description | Extracellular vesicles and exosomes generated from cystic renal epithelial cells promote cyst growth in autosomal dominant polycystic kidney disease |
| Authors | Ding H, Li LX, Harris PC, Yang J, Li X. |
| Journal name |
Nat Commun
|
| Publication year | 2021 |
| Sample | Embryonic kidney cells |
| Sample name | MEK - Pkd1-null |
| Molecules identified in the study | Protein miRNA |
| Methods used in the study | Western blotting qRT-PCR |
| EV-TRACK |
-
|
|
|
| 3
|
| Experiment ID | 2521 |
| Identified molecule | miRNA
|
| Identification method | qRT-PCR
|
| PubMed ID |
34315885
|
| Organism | Mus musculus |
| Experiment description | Extracellular vesicles and exosomes generated from cystic renal epithelial cells promote cyst growth in autosomal dominant polycystic kidney disease |
| Authors | Ding H, Li LX, Harris PC, Yang J, Li X. |
| Journal name |
Nat Commun
|
| Publication year | 2021 |
| Sample | Kidney epithelial cells |
| Sample name | PN24 - postnatal homozygous Pkd1-null |
| Molecules identified in the study | Protein miRNA |
| Methods used in the study | Western blotting Immuno-EM qRT-PCR |
| EV-TRACK |
-
|
|
|
| 4
|
| Experiment ID | 2522 |
| Identified molecule | miRNA
|
| Identification method | qRT-PCR
|
| PubMed ID |
34315885
|
| Organism | Mus musculus |
| Experiment description | Extracellular vesicles and exosomes generated from cystic renal epithelial cells promote cyst growth in autosomal dominant polycystic kidney disease |
| Authors | Ding H, Li LX, Harris PC, Yang J, Li X. |
| Journal name |
Nat Commun
|
| Publication year | 2021 |
| Sample | Kidney epithelial cells |
| Sample name | PH2 - postnatal heterozygous Pkd1 |
| Molecules identified in the study | Protein miRNA |
| Methods used in the study | Western blotting qRT-PCR |
| EV-TRACK |
-
|
|
|
| 5
|
| Experiment ID | 15 |
| Identified molecule | miRNA
|
| Identification method | miRCURY LNA Array
|
| PubMed ID |
17486113
|
| Organism | Mus musculus Homo sapiens |
| Experiment description | Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. |
| Authors | Valadi H, Ekströ, Bossios A, Sjöand M, Lee JJ, Lotvall JO |
| Journal name |
NCB
|
| Publication year | 2007 |
| Sample | Mast cells |
| Sample name | MC9 Bone marrow-derived mast cells HMC-1 |
| Molecules identified in the study | Protein mRNA miRNA |
| Methods used in the study | Mass spectrometry [MALDI TOF] Western blotting Microarray MicroRNA array [miRCURY LNA Array] |
| EV-TRACK |
-
|
|
|
| 6
|
| Experiment ID | 342 |
| Identified molecule | miRNA
|
| Identification method | RT-PCR
|
| PubMed ID |
22965126
|
| Organism | Mus musculus |
| Experiment description | Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells. |
| Authors | Bellingham SA, Coleman BM, Hill AF |
| Journal name |
Nucleic Acids Res
|
| Publication year | 2012 |
| Sample | Neuronal cells |
| Sample name | GT1-7 - Unifected Rep 1 |
| Molecules identified in the study | miRNA |
| Methods used in the study | RT-PCR Western blotting |
| EV-TRACK |
EV120028: EV-METRIC:22%
|
|
|
| 7
|
| Experiment ID | 343 |
| Identified molecule | miRNA
|
| Identification method | RT-PCR
|
| PubMed ID |
22965126
|
| Organism | Mus musculus |
| Experiment description | Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells. |
| Authors | Bellingham SA, Coleman BM, Hill AF |
| Journal name |
Nucleic Acids Res
|
| Publication year | 2012 |
| Sample | Neuronal cells |
| Sample name | GT1-7 - Unifected Rep 2 |
| Molecules identified in the study | miRNA |
| Methods used in the study | RT-PCR |
| EV-TRACK |
EV120028: EV-METRIC:22%
|
|
|
| 8
|
| Experiment ID | 344 |
| Identified molecule | miRNA
|
| Identification method | RT-PCR
|
| PubMed ID |
22965126
|
| Organism | Mus musculus |
| Experiment description | Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells. |
| Authors | Bellingham SA, Coleman BM, Hill AF |
| Journal name |
Nucleic Acids Res
|
| Publication year | 2012 |
| Sample | Neuronal cells |
| Sample name | GT1-7 - Prion infected Rep 1 |
| Molecules identified in the study | miRNA |
| Methods used in the study | RT-PCR Western blotting |
| EV-TRACK |
EV120028: EV-METRIC:22%
|
|
|
| 9
|
| Experiment ID | 345 |
| Identified molecule | miRNA
|
| Identification method | RT-PCR
|
| PubMed ID |
22965126
|
| Organism | Mus musculus |
| Experiment description | Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells. |
| Authors | Bellingham SA, Coleman BM, Hill AF |
| Journal name |
Nucleic Acids Res
|
| Publication year | 2012 |
| Sample | Neuronal cells |
| Sample name | GT1-7 - Prion infected Rep 2 |
| Molecules identified in the study | miRNA |
| Methods used in the study | RT-PCR |
| EV-TRACK |
EV120028: EV-METRIC:22%
|
|
|
| 10
|
| Experiment ID | 346 |
| Identified molecule | miRNA
|
| Identification method | RNA deep sequencing
|
| PubMed ID |
22965126
|
| Organism | Mus musculus |
| Experiment description | Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells. |
| Authors | Bellingham SA, Coleman BM, Hill AF |
| Journal name |
Nucleic Acids Res
|
| Publication year | 2012 |
| Sample | Neuronal cells |
| Sample name | GT1-7 - Prion infected and uninfected |
| Molecules identified in the study | Protein miRNA |
| Methods used in the study | RNA deep sequencing |
| EV-TRACK |
EV120028: EV-METRIC:22%
|
|
|