miRNA description for miR-21a-5p
miRNA accession miR-21a-5p
Species Mus musculus
 miR-21a-5p identified in exosomes derived from the following tissue/cell type
Adipocytes [Exosomes] 36640325   
Adipocytes [Exosomes] 36640325   
Colon cancer cells [Microvesicles] 34931471   
Mesenchymal stem cells [Exosomes] 36253358   
Neuroblastoma cells [Extracellular vesicles] 36594832   
Neuroblastoma cells [Extracellular vesicles] 36594832   
Neuroblastoma cells [Extracellular vesicles] 36594832   
Neuroblastoma cells [Extracellular vesicles] 36594832   
Neuroblastoma cells [Extracellular vesicles] 36594832   
Neuroblastoma cells [Extracellular vesicles] 36594832   
Neuroblastoma cells [Extracellular vesicles] 36594832   
Neuroblastoma cells [Extracellular vesicles] 36594832   
Neuroblastoma cells [Extracellular vesicles] 36594832   
Neuroblastoma cells [Extracellular vesicles] 36594832   
Neuroblastoma cells [Extracellular vesicles] 36594832   
Neuroblastoma cells [Extracellular vesicles] 36594832   
Neuroblastoma cells [Extracellular vesicles] 36594832   
Neuroblastoma cells [Extracellular vesicles] 36594832   
Plasma [Microvesicles] 34931471   
Primary cortical neurons [Extracellular vesicles] 36594832   
Primary cortical neurons [Extracellular vesicles] 36594832   
 Experiment description of studies that identified miR-21a-5p in exosomes
1
Experiment ID2332
Identified moleculemiRNA
Identification method Small RNA sequencing
PubMed ID 36640325   
OrganismMus musculus
Experiment descriptionExosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis
AuthorsTang Y, Yang LJ, Liu H, Song YJ, Yang QQ, Liu Y, Qian SW, Tang QQ.
Journal name Cell Rep
Publication year2023
SampleAdipocytes
Sample nameVisceral (gonadal) adipose tissue
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
Small RNA sequencing
RT-qPCR
EV-TRACK -
2
Experiment ID2333
Identified moleculemiRNA
Identification method Small RNA sequencing
PubMed ID 36640325   
OrganismMus musculus
Experiment descriptionExosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis
AuthorsTang Y, Yang LJ, Liu H, Song YJ, Yang QQ, Liu Y, Qian SW, Tang QQ.
Journal name Cell Rep
Publication year2023
SampleAdipocytes
Sample nameVisceral (gonadal) adipose tissue
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
Small RNA sequencing
RT-qPCR
EV-TRACK -
3
Experiment ID3375
Identified moleculemiRNA
Identification method Small RNA sequencing
PubMed ID 34931471   
OrganismMus musculus
Experiment descriptionExtracellular vesicles derived from tumour cells as a trigger of energy crisis in the skeletal muscle
AuthorsPin F, Beltrà M, Garcia-Castillo L, Pardini B, Birolo G, Matullo G, Penna F, Guttridge D, Costelli P.
Journal name J Cachexia Sarcopenia Muscle
Publication year2022
SampleColon cancer cells
Sample nameC26
Molecules identified in the studymiRNA
Methods used in the studySmall RNA sequencing
EV-TRACK -
4
Experiment ID1922
Identified moleculemiRNA
Identification method miRNA sequencing
qPCR
PubMed ID 36253358   
OrganismMus musculus
Experiment descriptionBone marrow mesenchymal stem cell-derived exosomal miR-21a-5p alleviates renal fibrosis by attenuating glycolysis by targeting PFKM
AuthorsXu S, Cheuk YC, Jia Y, Chen T, Chen J, Luo Y, Cao Y, Guo J, Dong L, Zhang Y, Shi Y, Rong R.
Journal name Cell Death Dis
Publication year2022
SampleMesenchymal stem cells
Sample nameBone marrow-derived MSCs
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
miRNA sequencing
qPCR
EV-TRACK -
5
Experiment ID1789
Identified moleculemiRNA
Identification method qPCR
PubMed ID 36594832   
OrganismMus musculus
Experiment descriptionDynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia
AuthorsKorvenlaita N, Gómez-Budia M, Scoyni F, Pistono C, Giudice L, Eamen S, Loppi S, de Sande AH, Huremagic B, Bouvy-Liivrand M, Heinäniemi M, Kaikkonen MU, Cheng L, Hill AF, Kanninen KM, Jenster GW, van Royen ME, Ramiro L, Montaner J, Batkova T, Mikulik R, Giugno R, Jolkkonen J, Korhonen P, Malm T.
Journal name J Extracell Vesicles
Publication year2023
SampleNeuroblastoma cells
Sample nameN2A
Molecules identified in the studymiRNA
Methods used in the studyqPCR
EV-TRACK -
6
Experiment ID1790
Identified moleculemiRNA
Identification method qPCR
PubMed ID 36594832   
OrganismMus musculus
Experiment descriptionDynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia
AuthorsKorvenlaita N, Gómez-Budia M, Scoyni F, Pistono C, Giudice L, Eamen S, Loppi S, de Sande AH, Huremagic B, Bouvy-Liivrand M, Heinäniemi M, Kaikkonen MU, Cheng L, Hill AF, Kanninen KM, Jenster GW, van Royen ME, Ramiro L, Montaner J, Batkova T, Mikulik R, Giugno R, Jolkkonen J, Korhonen P, Malm T.
Journal name J Extracell Vesicles
Publication year2023
SampleNeuroblastoma cells
Sample nameN2A
Molecules identified in the studymiRNA
Methods used in the studyqPCR
EV-TRACK -
7
Experiment ID1791
Identified moleculemiRNA
Identification method qPCR
PubMed ID 36594832   
OrganismMus musculus
Experiment descriptionDynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia
AuthorsKorvenlaita N, Gómez-Budia M, Scoyni F, Pistono C, Giudice L, Eamen S, Loppi S, de Sande AH, Huremagic B, Bouvy-Liivrand M, Heinäniemi M, Kaikkonen MU, Cheng L, Hill AF, Kanninen KM, Jenster GW, van Royen ME, Ramiro L, Montaner J, Batkova T, Mikulik R, Giugno R, Jolkkonen J, Korhonen P, Malm T.
Journal name J Extracell Vesicles
Publication year2023
SampleNeuroblastoma cells
Sample nameN2A
Molecules identified in the studymiRNA
Methods used in the studyqPCR
EV-TRACK -
8
Experiment ID1792
Identified moleculemiRNA
Identification method qPCR
PubMed ID 36594832   
OrganismMus musculus
Experiment descriptionDynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia
AuthorsKorvenlaita N, Gómez-Budia M, Scoyni F, Pistono C, Giudice L, Eamen S, Loppi S, de Sande AH, Huremagic B, Bouvy-Liivrand M, Heinäniemi M, Kaikkonen MU, Cheng L, Hill AF, Kanninen KM, Jenster GW, van Royen ME, Ramiro L, Montaner J, Batkova T, Mikulik R, Giugno R, Jolkkonen J, Korhonen P, Malm T.
Journal name J Extracell Vesicles
Publication year2023
SampleNeuroblastoma cells
Sample nameN2A
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
qPCR
EV-TRACK -
9
Experiment ID1793
Identified moleculemiRNA
Identification method qPCR
PubMed ID 36594832   
OrganismMus musculus
Experiment descriptionDynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia
AuthorsKorvenlaita N, Gómez-Budia M, Scoyni F, Pistono C, Giudice L, Eamen S, Loppi S, de Sande AH, Huremagic B, Bouvy-Liivrand M, Heinäniemi M, Kaikkonen MU, Cheng L, Hill AF, Kanninen KM, Jenster GW, van Royen ME, Ramiro L, Montaner J, Batkova T, Mikulik R, Giugno R, Jolkkonen J, Korhonen P, Malm T.
Journal name J Extracell Vesicles
Publication year2023
SampleNeuroblastoma cells
Sample nameN2A
Molecules identified in the studymiRNA
Methods used in the studyqPCR
EV-TRACK -
10
Experiment ID1794
Identified moleculemiRNA
Identification method qPCR
PubMed ID 36594832   
OrganismMus musculus
Experiment descriptionDynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia
AuthorsKorvenlaita N, Gómez-Budia M, Scoyni F, Pistono C, Giudice L, Eamen S, Loppi S, de Sande AH, Huremagic B, Bouvy-Liivrand M, Heinäniemi M, Kaikkonen MU, Cheng L, Hill AF, Kanninen KM, Jenster GW, van Royen ME, Ramiro L, Montaner J, Batkova T, Mikulik R, Giugno R, Jolkkonen J, Korhonen P, Malm T.
Journal name J Extracell Vesicles
Publication year2023
SampleNeuroblastoma cells
Sample nameN2A
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
qPCR
EV-TRACK -
11
Experiment ID1795
Identified moleculemiRNA
Identification method qPCR
PubMed ID 36594832   
OrganismMus musculus
Experiment descriptionDynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia
AuthorsKorvenlaita N, Gómez-Budia M, Scoyni F, Pistono C, Giudice L, Eamen S, Loppi S, de Sande AH, Huremagic B, Bouvy-Liivrand M, Heinäniemi M, Kaikkonen MU, Cheng L, Hill AF, Kanninen KM, Jenster GW, van Royen ME, Ramiro L, Montaner J, Batkova T, Mikulik R, Giugno R, Jolkkonen J, Korhonen P, Malm T.
Journal name J Extracell Vesicles
Publication year2023
SampleNeuroblastoma cells
Sample nameN2A
Molecules identified in the studymiRNA
Methods used in the studyqPCR
EV-TRACK -
12
Experiment ID1796
Identified moleculemiRNA
Identification method qPCR
PubMed ID 36594832   
OrganismMus musculus
Experiment descriptionDynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia
AuthorsKorvenlaita N, Gómez-Budia M, Scoyni F, Pistono C, Giudice L, Eamen S, Loppi S, de Sande AH, Huremagic B, Bouvy-Liivrand M, Heinäniemi M, Kaikkonen MU, Cheng L, Hill AF, Kanninen KM, Jenster GW, van Royen ME, Ramiro L, Montaner J, Batkova T, Mikulik R, Giugno R, Jolkkonen J, Korhonen P, Malm T.
Journal name J Extracell Vesicles
Publication year2023
SampleNeuroblastoma cells
Sample nameN2A
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
qPCR
EV-TRACK -
13
Experiment ID1797
Identified moleculemiRNA
Identification method qPCR
PubMed ID 36594832   
OrganismMus musculus
Experiment descriptionDynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia
AuthorsKorvenlaita N, Gómez-Budia M, Scoyni F, Pistono C, Giudice L, Eamen S, Loppi S, de Sande AH, Huremagic B, Bouvy-Liivrand M, Heinäniemi M, Kaikkonen MU, Cheng L, Hill AF, Kanninen KM, Jenster GW, van Royen ME, Ramiro L, Montaner J, Batkova T, Mikulik R, Giugno R, Jolkkonen J, Korhonen P, Malm T.
Journal name J Extracell Vesicles
Publication year2023
SampleNeuroblastoma cells
Sample nameN2A
Molecules identified in the studymiRNA
Methods used in the studyqPCR
EV-TRACK -
14
Experiment ID1798
Identified moleculemiRNA
Identification method qPCR
PubMed ID 36594832   
OrganismMus musculus
Experiment descriptionDynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia
AuthorsKorvenlaita N, Gómez-Budia M, Scoyni F, Pistono C, Giudice L, Eamen S, Loppi S, de Sande AH, Huremagic B, Bouvy-Liivrand M, Heinäniemi M, Kaikkonen MU, Cheng L, Hill AF, Kanninen KM, Jenster GW, van Royen ME, Ramiro L, Montaner J, Batkova T, Mikulik R, Giugno R, Jolkkonen J, Korhonen P, Malm T.
Journal name J Extracell Vesicles
Publication year2023
SampleNeuroblastoma cells
Sample nameN2A
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
qPCR
EV-TRACK -
15
Experiment ID1799
Identified moleculemiRNA
Identification method qPCR
PubMed ID 36594832   
OrganismMus musculus
Experiment descriptionDynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia
AuthorsKorvenlaita N, Gómez-Budia M, Scoyni F, Pistono C, Giudice L, Eamen S, Loppi S, de Sande AH, Huremagic B, Bouvy-Liivrand M, Heinäniemi M, Kaikkonen MU, Cheng L, Hill AF, Kanninen KM, Jenster GW, van Royen ME, Ramiro L, Montaner J, Batkova T, Mikulik R, Giugno R, Jolkkonen J, Korhonen P, Malm T.
Journal name J Extracell Vesicles
Publication year2023
SampleNeuroblastoma cells
Sample nameN2A - Fractions 1-4
Molecules identified in the studymiRNA
Methods used in the studyqPCR
EV-TRACK -
16
Experiment ID1800
Identified moleculemiRNA
Identification method qPCR
PubMed ID 36594832   
OrganismMus musculus
Experiment descriptionDynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia
AuthorsKorvenlaita N, Gómez-Budia M, Scoyni F, Pistono C, Giudice L, Eamen S, Loppi S, de Sande AH, Huremagic B, Bouvy-Liivrand M, Heinäniemi M, Kaikkonen MU, Cheng L, Hill AF, Kanninen KM, Jenster GW, van Royen ME, Ramiro L, Montaner J, Batkova T, Mikulik R, Giugno R, Jolkkonen J, Korhonen P, Malm T.
Journal name J Extracell Vesicles
Publication year2023
SampleNeuroblastoma cells
Sample nameN2A - Fractions 1-4
Molecules identified in the studymiRNA
Methods used in the studyqPCR
EV-TRACK -
17
Experiment ID1801
Identified moleculemiRNA
Identification method qPCR
PubMed ID 36594832   
OrganismMus musculus
Experiment descriptionDynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia
AuthorsKorvenlaita N, Gómez-Budia M, Scoyni F, Pistono C, Giudice L, Eamen S, Loppi S, de Sande AH, Huremagic B, Bouvy-Liivrand M, Heinäniemi M, Kaikkonen MU, Cheng L, Hill AF, Kanninen KM, Jenster GW, van Royen ME, Ramiro L, Montaner J, Batkova T, Mikulik R, Giugno R, Jolkkonen J, Korhonen P, Malm T.
Journal name J Extracell Vesicles
Publication year2023
SampleNeuroblastoma cells
Sample nameN2A - Fractions 1-4
Molecules identified in the studymiRNA
Methods used in the studyqPCR
EV-TRACK -
18
Experiment ID1802
Identified moleculemiRNA
Identification method qPCR
PubMed ID 36594832   
OrganismMus musculus
Experiment descriptionDynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia
AuthorsKorvenlaita N, Gómez-Budia M, Scoyni F, Pistono C, Giudice L, Eamen S, Loppi S, de Sande AH, Huremagic B, Bouvy-Liivrand M, Heinäniemi M, Kaikkonen MU, Cheng L, Hill AF, Kanninen KM, Jenster GW, van Royen ME, Ramiro L, Montaner J, Batkova T, Mikulik R, Giugno R, Jolkkonen J, Korhonen P, Malm T.
Journal name J Extracell Vesicles
Publication year2023
SampleNeuroblastoma cells
Sample nameN2A - Fractions 1-4
Molecules identified in the studymiRNA
Methods used in the studyqPCR
EV-TRACK -
19
Experiment ID3374
Identified moleculemiRNA
Identification method Small RNA sequencing
PubMed ID 34931471   
OrganismMus musculus
Experiment descriptionExtracellular vesicles derived from tumour cells as a trigger of energy crisis in the skeletal muscle
AuthorsPin F, Beltrà M, Garcia-Castillo L, Pardini B, Birolo G, Matullo G, Penna F, Guttridge D, Costelli P.
Journal name J Cachexia Sarcopenia Muscle
Publication year2022
SamplePlasma
Sample nameBALB/C - subcutaneously implanted with C26 cells
Molecules identified in the studymiRNA
Methods used in the studySmall RNA sequencing
ddPCR
EV-TRACK -
20
Experiment ID1787
Identified moleculemiRNA
Identification method qPCR
PubMed ID 36594832   
OrganismMus musculus
Experiment descriptionDynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia
AuthorsKorvenlaita N, Gómez-Budia M, Scoyni F, Pistono C, Giudice L, Eamen S, Loppi S, de Sande AH, Huremagic B, Bouvy-Liivrand M, Heinäniemi M, Kaikkonen MU, Cheng L, Hill AF, Kanninen KM, Jenster GW, van Royen ME, Ramiro L, Montaner J, Batkova T, Mikulik R, Giugno R, Jolkkonen J, Korhonen P, Malm T.
Journal name J Extracell Vesicles
Publication year2023
SamplePrimary cortical neurons
Sample nameCXN - C57Bl/6J mice embryos
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
qPCR
EV-TRACK -
21
Experiment ID1788
Identified moleculemiRNA
Identification method qPCR
PubMed ID 36594832   
OrganismMus musculus
Experiment descriptionDynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia
AuthorsKorvenlaita N, Gómez-Budia M, Scoyni F, Pistono C, Giudice L, Eamen S, Loppi S, de Sande AH, Huremagic B, Bouvy-Liivrand M, Heinäniemi M, Kaikkonen MU, Cheng L, Hill AF, Kanninen KM, Jenster GW, van Royen ME, Ramiro L, Montaner J, Batkova T, Mikulik R, Giugno R, Jolkkonen J, Korhonen P, Malm T.
Journal name J Extracell Vesicles
Publication year2023
SamplePrimary cortical neurons
Sample nameCXN - C57Bl/6J mice embryos
Molecules identified in the studymiRNA
Methods used in the studyqPCR
EV-TRACK -