Gene description for RAPGEF2
Gene name	Rap guanine nucleotide exchange factor 2
Gene symbol	RAPGEF2
Other names/aliases	PDZ-GEF1 RA-GEF-1 nRap GEP
Species	Bos taurus
Experiment description of studies that identified RAPGEF2 in Bovine milk
1 Experiment ID 439 Identified molecule protein Extracellular vesicle type Exosomes/Membrane vesicles MISEV EVs Identification method Mass spectrometry PubMed ID 22129587    Organism Bos taurus Experiment description Bovine milk exosome proteome. Authors Reinhardt TA, Lippolis JD, Nonnecke BJ, Sacco RE. Journal name J Proteomics Publication year 2012 Sample Bovine milk Sample name Normal cow-Milk Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV120041: EV-METRIC:56%
2 Experiment ID 503 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 23459212    Organism Bos taurus Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis. Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD. Journal name J Proteomics Publication year 2013 Sample Bovine milk Sample name Staphylococcus aureus-infected-Milk Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130111: EV-METRIC:43%
3 Experiment ID 1047 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 28725021    Organism Bos taurus Experiment description Bovine milk-derived exosomes from colostrum are enriched with proteins implicated in immune response and growth. Authors Samuel M, Chisanga D, Liem M, Keerthikumar S, Anand S, Ang CS, Adda CG, Versteegen E, Jois M, Mathivanan S. Journal name Sci Rep. Publication year 2017 Sample Bovine milk Sample name Bovine milk - colostrum 48 h Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density 1.08.1.24 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK -
4 Experiment ID 1048 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 28725021    Organism Bos taurus Experiment description Bovine milk-derived exosomes from colostrum are enriched with proteins implicated in immune response and growth. Authors Samuel M, Chisanga D, Liem M, Keerthikumar S, Anand S, Ang CS, Adda CG, Versteegen E, Jois M, Mathivanan S. Journal name Sci Rep. Publication year 2017 Sample Bovine milk Sample name Bovine milk - mature milk Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density 1.08.1.24 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK -