Gene description for GJA3
Gene name gap junction protein alpha 3
Gene symbol GJA3
Other names/aliases -
Species Bos taurus
 Experiment description of studies that identified GJA3 in Bovine milk

1
Experiment ID960
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 26047123   
OrganismBos taurus
Experiment descriptionOral administration of bovine milk derived extracellular vesicles attenuates arthritis in two mouse models.
AuthorsArntz OJ, Pieters BC, Oliveira MC, Broeren MG, Bennink MB, de Vries M, van Lent PL, Koenders MI, van den Berg WB, van der Kraan PM, van de Loo FA.
Journal name Mol Nutr Food Res.
Publication year2015
SampleBovine milk
Sample nameBovine milk
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Filtration
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV150035: EV-METRIC:29%

2
Experiment ID2815
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 34168137   
OrganismBos taurus
Experiment descriptionOral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis
AuthorsSamuel M, Fonseka P, Sanwlani R, Gangoda L, Chee SH, Keerthikumar S, Spurling A, Chitti SV, Zanker D, Ang CS, Atukorala I, Kang T, Shahi S, Marzan AL, Nedeva C, Vennin C, Lucas MC, Cheng L, Herrmann D, Pathan M, Chisanga D, Warren SC, Zhao K, Abraham N, Anand S, Boukouris S, Adda CG, Jiang L, Shekhar TM, Baschuk N, Hawkins CJ, Johnston AJ, Orian JM, Hoogenraad NJ, Poon IK, Hill AF, Jois M, Timpson P, Parker BS, Mathivanan S.
Journal name Nat Commun
Publication year2021
SampleBovine milk
Sample nameRaw milk
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
mRNA
miRNA
tRNA
Methods used in the studyWestern blotting
Mass spectrometry
Small RNA sequencing
EV-TRACK -

3
Experiment ID2822
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 34168137   
OrganismBos taurus
Experiment descriptionOral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis
AuthorsSamuel M, Fonseka P, Sanwlani R, Gangoda L, Chee SH, Keerthikumar S, Spurling A, Chitti SV, Zanker D, Ang CS, Atukorala I, Kang T, Shahi S, Marzan AL, Nedeva C, Vennin C, Lucas MC, Cheng L, Herrmann D, Pathan M, Chisanga D, Warren SC, Zhao K, Abraham N, Anand S, Boukouris S, Adda CG, Jiang L, Shekhar TM, Baschuk N, Hawkins CJ, Johnston AJ, Orian JM, Hoogenraad NJ, Poon IK, Hill AF, Jois M, Timpson P, Parker BS, Mathivanan S.
Journal name Nat Commun
Publication year2021
SampleBovine milk
Sample nameCommercial milk
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
mRNA
miRNA
tRNA
Methods used in the studyMass spectrometry
Small RNA sequencing
EV-TRACK -

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