Gene description for HUWE1
Gene name	HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1
Gene symbol	HUWE1
Other names/aliases	ARF-BP1 HECTH9 HSPC272 Ib772 LASU1 MRXST MULE URE-B1 UREB1
Species	Homo sapiens
Experiment description of studies that identified HUWE1 in Pancreatic duct epithelial cells
1 Experiment ID 1660 Identified molecule Protein Extracellular vesicle type Exosomes MISEV Small EVs Identification method Mass spectrometry PubMed ID 34108659    Organism Homo sapiens Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Authors Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R. Journal name Nat Cell Biol Publication year 2021 Sample Pancreatic duct epithelial cells Sample name HPDE Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein mRNA Methods used in the study RT-qPCR Western blotting Mass spectrometry Flow cytometry EV-TRACK -
2 Experiment ID 1661 Identified molecule Protein Extracellular vesicle type Exosomes MISEV Small EVs Identification method Mass spectrometry PubMed ID 34108659    Organism Homo sapiens Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker Authors Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R. Journal name Nat Cell Biol Publication year 2021 Sample Pancreatic duct epithelial cells Sample name HPNE Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein mRNA Methods used in the study RT-qPCR Western blotting Mass spectrometry Flow cytometry EV-TRACK -
3 Experiment ID 2676 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35656858    Organism Homo sapiens Experiment description A multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells Authors Hinzman CP, Singh B, Bansal S, Li Y, Iliuk A, Girgis M, Herremans KM, Trevino JG, Singh VK, Banerjee PP, Cheema AK. Journal name J Extracell Vesicles Publication year 2022 Sample Pancreatic duct epithelial cells Sample name hTERT-HPNE Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Lipid Metabolite Methods used in the study Western blotting Mass spectrometry EV-TRACK -
4 Experiment ID 2677 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35656858    Organism Homo sapiens Experiment description A multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells Authors Hinzman CP, Singh B, Bansal S, Li Y, Iliuk A, Girgis M, Herremans KM, Trevino JG, Singh VK, Banerjee PP, Cheema AK. Journal name J Extracell Vesicles Publication year 2022 Sample Pancreatic duct epithelial cells Sample name HPDE-H6c7 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Lipid Metabolite Methods used in the study Western blotting Mass spectrometry EV-TRACK -
5 Experiment ID 2684 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35656858    Organism Homo sapiens Experiment description A multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells Authors Hinzman CP, Singh B, Bansal S, Li Y, Iliuk A, Girgis M, Herremans KM, Trevino JG, Singh VK, Banerjee PP, Cheema AK. Journal name J Extracell Vesicles Publication year 2022 Sample Pancreatic duct epithelial cells Sample name hTERT-HPNE Isolation/purification methods EVtrap Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
6 Experiment ID 2685 Identified molecule Protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 35656858    Organism Homo sapiens Experiment description A multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells Authors Hinzman CP, Singh B, Bansal S, Li Y, Iliuk A, Girgis M, Herremans KM, Trevino JG, Singh VK, Banerjee PP, Cheema AK. Journal name J Extracell Vesicles Publication year 2022 Sample Pancreatic duct epithelial cells Sample name HPDE-H6c7 Isolation/purification methods EVtrap Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -