Gene description for FLOT1
Gene name	flotillin 1
Gene symbol	FLOT1
Other names/aliases	-
Species	Homo sapiens
Experiment description of studies that identified FLOT1 in Endothelial cells
1 Experiment ID 265 Identified molecule protein Extracellular vesicle type Microvesicles MISEV EVs Identification method Western blotting PubMed ID 18425114    Organism Homo sapiens Experiment description Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells Authors Al-Nedawi K, Meehan B, Micallef J, Lhotak V, May L, Guha A, Rak J Journal name Nat Cell Biol Publication year 2008 Sample Endothelial cells Sample name HUVECs Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
2 Experiment ID 301 Identified molecule protein Extracellular vesicle type Microvesicles MISEV EVs Identification method Western blotting PubMed ID 19234131    Organism Homo sapiens Experiment description Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR Authors Al-Nedawi K, Meehan B, Kerbel RS, Allison AC, Rak J Journal name Proc Natl Acad Sci U S A Publication year 2009 Sample Endothelial cells Sample name HUVECs Isolation/purification methods Differential centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
3 Experiment ID 385 Identified molecule protein Extracellular vesicle type Microparticles MISEV EVs Identification method Mass spectrometry PubMed ID 18563738    Organism Homo sapiens Experiment description Comparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles. Authors Peterson DB, Sander T, Kaul S, Wakim BT, Halligan B, Twigger S, Pritchard KA Jr, Oldham KT, Ou JS. Journal name Proteomics Publication year 2008 Sample Endothelial cells Sample name Endothelial cells (HUVEC) Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
4 Experiment ID 386 Identified molecule protein Extracellular vesicle type Microparticles MISEV EVs Identification method Mass spectrometry PubMed ID 18563738    Organism Homo sapiens Experiment description Comparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles. Authors Peterson DB, Sander T, Kaul S, Wakim BT, Halligan B, Twigger S, Pritchard KA Jr, Oldham KT, Ou JS. Journal name Proteomics Publication year 2008 Sample Endothelial cells Sample name Treated by PAI-1-Endothelial cell (HUVEC) Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
5 Experiment ID 387 Identified molecule protein Extracellular vesicle type Microparticles MISEV EVs Identification method Mass spectrometry PubMed ID 18563738    Organism Homo sapiens Experiment description Comparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles. Authors Peterson DB, Sander T, Kaul S, Wakim BT, Halligan B, Twigger S, Pritchard KA Jr, Oldham KT, Ou JS. Journal name Proteomics Publication year 2008 Sample Endothelial cells Sample name Treated by TNF-alpha-Endothelial cells (HUVEC) Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK -
6 Experiment ID 551 Identified molecule protein Extracellular vesicle type Exosomes/Extracellular vesicles MISEV EVs Identification method Mass spectrometry PubMed ID 24009886    Organism Homo sapiens Experiment description Cellular stress conditions are reflected in the protein and RNA content of endothelial cell-derived exosomes. Authors de Jong OG, Verhaar MC, Chen Y, Vader P, Gremmels H, Posthuma G, Schiffelers RM, Gucek M, van Balkom BW. Journal name J Extracell Vesicles Publication year 2012 Sample Endothelial cells Sample name Stressed (hypoxia, TNF-alpha-induced activation, high glucose and mannose concentrations)-Endothelial cells (HMEC-1) Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV120004: EV-METRIC:67%