Gene description for MRGPRX2
Gene name MAS related GPR family member X2
Gene symbol MRGPRX2
Other names/aliases MGRG3
MRGX2
Species Homo sapiens
 Experiment description of studies that identified MRGPRX2 in Serum

1
Experiment ID1502
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 33953168   
OrganismHomo sapiens
Experiment descriptionMastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation
AuthorsKim DK, Bandara G, Cho YE, Komarow HD, Donahue DR, Karim B, Baek MC, Kim HM, Metcalfe DD, Olivera A.
Journal name Nat Commun
Publication year2021
SampleSerum
Sample nameSystemic mastocytosis patients - Tryptase <110 ng/mL
Isolation/purification methodsExoQuick Kit
Flotation density-
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
qRT-PCR
EV-TRACK -

2
Experiment ID1503
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 33953168   
OrganismHomo sapiens
Experiment descriptionMastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation
AuthorsKim DK, Bandara G, Cho YE, Komarow HD, Donahue DR, Karim B, Baek MC, Kim HM, Metcalfe DD, Olivera A.
Journal name Nat Commun
Publication year2021
SampleSerum
Sample nameSystemic mastocytosis patients - Tryptase >110 ng/mL
Isolation/purification methodsExoQuick Kit
Flotation density-
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
qRT-PCR
EV-TRACK -

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