Gene description for App
Gene name	amyloid beta precursor protein
Gene symbol	App
Other names/aliases	Abeta Abpp Adap Ag Cvap E030013M08Rik betaApp
Species	Mus musculus
Experiment description of studies that identified App in Forebrain neurons
1 Experiment ID 1645 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 29348617    Organism Mus musculus Experiment description Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures Authors Miranda AM, Lasiecka ZM, Xu Y, Neufeld J, Shahriar S, Simoes S, Chan RB, Oliveira TG, Small SA, Di Paolo G. Journal name Nat Commun Publication year 2018 Sample Forebrain neurons Sample name C57BL/6 Pik3c3flox/flox Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Lipid Methods used in the study Western blotting LC-MS EV-TRACK -
2 Experiment ID 1646 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 29348617    Organism Mus musculus Experiment description Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures Authors Miranda AM, Lasiecka ZM, Xu Y, Neufeld J, Shahriar S, Simoes S, Chan RB, Oliveira TG, Small SA, Di Paolo G. Journal name Nat Commun Publication year 2018 Sample Forebrain neurons Sample name C57BL/6 Pik3c3flox/flox crossed with transgenic C57BL/6 CaMKIIα-Cre Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Lipid Methods used in the study Western blotting LC-MS EV-TRACK -