Gene description for App
Gene name	amyloid beta precursor protein
Gene symbol	App
Other names/aliases	Abeta Abpp Adap Ag Cvap E030013M08Rik betaApp
Species	Mus musculus
Experiment description of studies that identified App in Neuroblastoma cells
1 Experiment ID 1631 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 29348617    Organism Mus musculus Experiment description Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures Authors Miranda AM, Lasiecka ZM, Xu Y, Neufeld J, Shahriar S, Simoes S, Chan RB, Oliveira TG, Small SA, Di Paolo G. Journal name Nat Commun Publication year 2018 Sample Neuroblastoma cells Sample name N2a Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Lipid Methods used in the study Western blotting LC-MS EV-TRACK -
2 Experiment ID 1632 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 29348617    Organism Mus musculus Experiment description Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures Authors Miranda AM, Lasiecka ZM, Xu Y, Neufeld J, Shahriar S, Simoes S, Chan RB, Oliveira TG, Small SA, Di Paolo G. Journal name Nat Commun Publication year 2018 Sample Neuroblastoma cells Sample name N2a Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Lipid Methods used in the study Western blotting LC-MS EV-TRACK -
3 Experiment ID 1632 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 29348617    Organism Mus musculus Experiment description Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures Authors Miranda AM, Lasiecka ZM, Xu Y, Neufeld J, Shahriar S, Simoes S, Chan RB, Oliveira TG, Small SA, Di Paolo G. Journal name Nat Commun Publication year 2018 Sample Neuroblastoma cells Sample name N2a Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Lipid Methods used in the study Western blotting LC-MS EV-TRACK -
4 Experiment ID 1636 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 29348617    Organism Mus musculus Experiment description Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures Authors Miranda AM, Lasiecka ZM, Xu Y, Neufeld J, Shahriar S, Simoes S, Chan RB, Oliveira TG, Small SA, Di Paolo G. Journal name Nat Commun Publication year 2018 Sample Neuroblastoma cells Sample name N2a - 100K pellet Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
5 Experiment ID 1637 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 29348617    Organism Mus musculus Experiment description Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures Authors Miranda AM, Lasiecka ZM, Xu Y, Neufeld J, Shahriar S, Simoes S, Chan RB, Oliveira TG, Small SA, Di Paolo G. Journal name Nat Commun Publication year 2018 Sample Neuroblastoma cells Sample name N2a Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Lipid Methods used in the study Western blotting LC-MS EV-TRACK -
6 Experiment ID 1647 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 29348617    Organism Mus musculus Experiment description Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures Authors Miranda AM, Lasiecka ZM, Xu Y, Neufeld J, Shahriar S, Simoes S, Chan RB, Oliveira TG, Small SA, Di Paolo G. Journal name Nat Commun Publication year 2018 Sample Neuroblastoma cells Sample name N2a Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
7 Experiment ID 1648 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 29348617    Organism Mus musculus Experiment description Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures Authors Miranda AM, Lasiecka ZM, Xu Y, Neufeld J, Shahriar S, Simoes S, Chan RB, Oliveira TG, Small SA, Di Paolo G. Journal name Nat Commun Publication year 2018 Sample Neuroblastoma cells Sample name N2a Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
8 Experiment ID 1649 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 29348617    Organism Mus musculus Experiment description Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures Authors Miranda AM, Lasiecka ZM, Xu Y, Neufeld J, Shahriar S, Simoes S, Chan RB, Oliveira TG, Small SA, Di Paolo G. Journal name Nat Commun Publication year 2018 Sample Neuroblastoma cells Sample name N2a Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
9 Experiment ID 1650 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 29348617    Organism Mus musculus Experiment description Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures Authors Miranda AM, Lasiecka ZM, Xu Y, Neufeld J, Shahriar S, Simoes S, Chan RB, Oliveira TG, Small SA, Di Paolo G. Journal name Nat Commun Publication year 2018 Sample Neuroblastoma cells Sample name N2a Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
10 Experiment ID 1651 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 29348617    Organism Mus musculus Experiment description Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures Authors Miranda AM, Lasiecka ZM, Xu Y, Neufeld J, Shahriar S, Simoes S, Chan RB, Oliveira TG, Small SA, Di Paolo G. Journal name Nat Commun Publication year 2018 Sample Neuroblastoma cells Sample name N2a Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
11 Experiment ID 1652 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 29348617    Organism Mus musculus Experiment description Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures Authors Miranda AM, Lasiecka ZM, Xu Y, Neufeld J, Shahriar S, Simoes S, Chan RB, Oliveira TG, Small SA, Di Paolo G. Journal name Nat Commun Publication year 2018 Sample Neuroblastoma cells Sample name N2a Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -