Gene description for MAPK14
Gene name mitogen-activated protein kinase 14
Gene symbol MAPK14
Other names/aliases CSBP
CSBP1
CSBP2
CSPB1
EXIP
Mxi2
PRKM14
PRKM15
RK
SAPK2A
p38
p38ALPHA
Species Homo sapiens
 Experiment description of studies that identified MAPK14 in Plasma

1
Experiment ID2848
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 35058437   
OrganismHomo sapiens
Experiment descriptionCirculating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2
AuthorsEl-Shennawy L, Hoffmann AD, Dashzeveg NK, McAndrews KM, Mehl PJ, Cornish D, Yu Z, Tokars VL, Nicolaescu V, Tomatsidou A, Mao C, Felicelli CJ, Tsai CF, Ostiguin C, Jia Y, Li L, Furlong K, Wysocki J, Luo X, Ruivo CF, Batlle D, Hope TJ, Shen Y, Chae YK, Zhang H, LeBleu VS, Shi T, Swaminathan S, Luo Y, Missiakas D, Randall GC, Demonbreun AR, Ison MG, Kalluri R, Fang D, Liu H.
Journal name Nat Commun
Publication year2022
SamplePlasma
Sample nameNWL-001 - Lung cancer patient
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Mass spectrometry
EV-TRACK -

2
Experiment ID2130
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method ELISA
PubMed ID 36515353   
OrganismHomo sapiens
Experiment descriptionOral nicotinamide riboside raises NAD+ and lowers biomarkers of neurodegenerative pathology in plasma extracellular vesicles enriched for neuronal origin
AuthorsVreones M, Mustapic M, Moaddel R, Pucha KA, Lovett J, Seals DR, Kapogiannis D, Martens CR.
Journal name Aging Cell
Publication year2023
SamplePlasma
Sample namePatient-derived neuronal origin EVs (enriched)
Isolation/purification methodsExoQuick Kit
Centrifugation
Flotation density-
Molecules identified in the studyMetabolite
Protein
Methods used in the studyMass spectometry
Luciferase assay
ELISA
EV-TRACK -

3
Experiment ID2131
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method ELISA
PubMed ID 36515353   
OrganismHomo sapiens
Experiment descriptionOral nicotinamide riboside raises NAD+ and lowers biomarkers of neurodegenerative pathology in plasma extracellular vesicles enriched for neuronal origin
AuthorsVreones M, Mustapic M, Moaddel R, Pucha KA, Lovett J, Seals DR, Kapogiannis D, Martens CR.
Journal name Aging Cell
Publication year2023
SamplePlasma
Sample namePatient-derived neuronal origin EVs (enriched)
Isolation/purification methodsExoQuick Kit
Centrifugation
Flotation density-
Molecules identified in the studyMetabolite
Protein
Methods used in the studyMass spectometry
Luciferase assay
ELISA
EV-TRACK -

4
Experiment ID2132
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method ELISA
PubMed ID 36515353   
OrganismHomo sapiens
Experiment descriptionOral nicotinamide riboside raises NAD+ and lowers biomarkers of neurodegenerative pathology in plasma extracellular vesicles enriched for neuronal origin
AuthorsVreones M, Mustapic M, Moaddel R, Pucha KA, Lovett J, Seals DR, Kapogiannis D, Martens CR.
Journal name Aging Cell
Publication year2023
SamplePlasma
Sample namePatient-derived neuronal origin EVs (enriched) - responders
Isolation/purification methodsExoQuick Kit
Centrifugation
Flotation density-
Molecules identified in the studyMetabolite
Protein
Methods used in the studyELISA
EV-TRACK -

5
Experiment ID2133
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method ELISA
PubMed ID 36515353   
OrganismHomo sapiens
Experiment descriptionOral nicotinamide riboside raises NAD+ and lowers biomarkers of neurodegenerative pathology in plasma extracellular vesicles enriched for neuronal origin
AuthorsVreones M, Mustapic M, Moaddel R, Pucha KA, Lovett J, Seals DR, Kapogiannis D, Martens CR.
Journal name Aging Cell
Publication year2023
SamplePlasma
Sample namePatient-derived neuronal origin EVs (enriched) - responders
Isolation/purification methodsExoQuick Kit
Centrifugation
Flotation density-
Molecules identified in the studyMetabolite
Protein
Methods used in the studyELISA
EV-TRACK -

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