Gene description for Itga2b
Gene name	integrin alpha 2b
Gene symbol	Itga2b
Other names/aliases	CD41 CD41B GpIIb alphaIIb
Species	Mus musculus
Experiment description of studies that identified Itga2b in Platelets
1 Experiment ID 1345 Identified molecule protein Extracellular vesicle type Platelet-derived microparticles MISEV EV-like nanoparticles Identification method Flow cytometry PubMed ID 33009394    Organism Mus musculus Experiment description Platelet-derived microparticles enhance megakaryocyte differentiation and platelet generation via miR-1915-3p Authors Qu M, Zou X, Fang F, Wang S, Xu L, Zeng Q, Fan Z, Chen L, Yue W, Xie X, Pei X. Journal name Nat Commun Publication year 2020 Sample Platelets Sample name Platelets derived from peripheral blood - C57BL/6 Isolation/purification methods Differential centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Flow cytometry EV-TRACK -
2 Experiment ID 2538 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Large EVs Identification method Flow cytometry PubMed ID 34293122    Organism Mus musculus Experiment description Platelet EVs contain an active proteasome involved in protein processing for antigen presentation via MHC-I molecules Authors Marcoux G, Laroche A, Hasse S, Bellio M, Mbarik M, Tamagne M, Allaeys I, Zufferey A, Lévesque T, Rebetz J, Karakeussian-Rimbaud A, Turgeon J, Bourgoin SG, Hamzeh-Cognasse H, Cognasse F, Kapur R, Semple JW, Hébert MJ, Pirenne F, Overkleeft HS, Florea BI, Dieude M, Vingert B, Boilard E. Journal name Blood Publication year 2021 Sample Platelets Sample name Platelets collected using 20% acid citrate dextrose Isolation/purification methods Centrifugation Flotation density - Molecules identified in the study Protein Lipid Methods used in the study Flow cytometry EV-TRACK -
3 Experiment ID 2539 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Large EVs Identification method Flow cytometry PubMed ID 34293122    Organism Mus musculus Experiment description Platelet EVs contain an active proteasome involved in protein processing for antigen presentation via MHC-I molecules Authors Marcoux G, Laroche A, Hasse S, Bellio M, Mbarik M, Tamagne M, Allaeys I, Zufferey A, Lévesque T, Rebetz J, Karakeussian-Rimbaud A, Turgeon J, Bourgoin SG, Hamzeh-Cognasse H, Cognasse F, Kapur R, Semple JW, Hébert MJ, Pirenne F, Overkleeft HS, Florea BI, Dieude M, Vingert B, Boilard E. Journal name Blood Publication year 2021 Sample Platelets Sample name Platelets collected using 20% acid citrate dextrose Isolation/purification methods Centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Flow cytometry EV-TRACK -
4 Experiment ID 2540 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Large EVs Identification method Flow cytometry PubMed ID 34293122    Organism Mus musculus Experiment description Platelet EVs contain an active proteasome involved in protein processing for antigen presentation via MHC-I molecules Authors Marcoux G, Laroche A, Hasse S, Bellio M, Mbarik M, Tamagne M, Allaeys I, Zufferey A, Lévesque T, Rebetz J, Karakeussian-Rimbaud A, Turgeon J, Bourgoin SG, Hamzeh-Cognasse H, Cognasse F, Kapur R, Semple JW, Hébert MJ, Pirenne F, Overkleeft HS, Florea BI, Dieude M, Vingert B, Boilard E. Journal name Blood Publication year 2021 Sample Platelets Sample name Platelets collected using citrated tubes Isolation/purification methods Centrifugation Flotation density - Molecules identified in the study Protein Lipid Methods used in the study Flow cytometry EV-TRACK -