Gene description for Itih4
Gene name inter alpha-trypsin inhibitor, heavy chain 4
Gene symbol Itih4
Other names/aliases ITI-HC4
Itih-4
PK-120
Species Mus musculus
 Experiment description of studies that identified Itih4 in Plasma

1
Experiment ID3511
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 31068461   
OrganismHomo sapiens
Experiment descriptionExtracellular vesicle fibrinogen induces encephalitogenic CD8+ T cells in a mouse model of multiple sclerosis
AuthorsWillis CM, Nicaise AM, Menoret A, Ryu JK, Mendiola AS, Jellison ER, Givogri MI, Han DK, Bongarzone ER, Akassoglou K, Vella AT, Crocker SJ.
Journal name Proc Natl Acad Sci U S A
Publication year2019
SamplePlasma
Sample nameHealthy donors
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Mass spectrometry
EV-TRACK -

2
Experiment ID3512
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 31068461   
OrganismHomo sapiens
Experiment descriptionExtracellular vesicle fibrinogen induces encephalitogenic CD8+ T cells in a mouse model of multiple sclerosis
AuthorsWillis CM, Nicaise AM, Menoret A, Ryu JK, Mendiola AS, Jellison ER, Givogri MI, Han DK, Bongarzone ER, Akassoglou K, Vella AT, Crocker SJ.
Journal name Proc Natl Acad Sci U S A
Publication year2019
SamplePlasma
Sample nameRelapsing-remitting multiple sclerosis patients
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Mass spectrometry
EV-TRACK -

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