Gene description for Npc1
Gene name NPC intracellular cholesterol transporter 1
Gene symbol Npc1
Other names/aliases A430089E03Rik
D18Ertd139e
D18Ertd723e
lcsd
nmf164
spm
Species Mus musculus
 Experiment description of studies that identified Npc1 in Adipocytes

1
Experiment ID2370
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 36759608   
OrganismHomo sapiens
Experiment descriptionAdipocyte-derived extracellular vesicles increase insulin secretion through transport of insulinotropic protein cargo
AuthorsKulaj K, Harger A, Bauer M, Caliskan ÖS, Gupta TK, Chiang DM, Milbank E, Reber J, Karlas A, Kotzbeck P, Sailer DN, Volta F, Lutter D, Prakash S, Merl-Pham J, Ntziachristos V, Hauner H, Pfaffl MW, Tschöp MH, Müller TD, Hauck SM, Engel BD, Gerdes JM, Pfluger PT, Krahmer N, Stemmer K.
Journal name Nat Commun
Publication year2023
SampleAdipocytes
Sample nameLiposuction patient-derived adipocytes
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Size exclusion chromatography
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
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