Gene description for Pdcd6ip
Gene name	programmed cell death 6 interacting protein
Gene symbol	Pdcd6ip
Other names/aliases	Aip1 Alix Eig2 mKIAA1375
Species	Mus musculus
Experiment description of studies that identified Pdcd6ip in Breast cancer cells
1 Experiment ID 737 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 25220352    Organism Mus musculus Experiment description Surface functionalization of exosomes using click chemistry. Authors Smyth T, Petrova K, Payton NM, Persaud I, Redzic JS, Graner MW, Smith-Jones P, Anchordoquy TJ. Journal name Bioconjug Chem Publication year 2014 Sample Breast cancer cells Sample name 4T1 Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density 1.1-1.2 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV140392: EV-METRIC:14%
2 Experiment ID 1051 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry Western blotting PubMed ID 29115712    Organism Mus musculus Experiment description Proteomic Profiling of Exosomes Secreted by Breast Cancer Cells with Varying Metastatic Potential. Authors Gangoda L, Liem M, Ang CS, Keerthikumar S, Adda CG, Parker BS, Mathivanan S. Journal name Proteomics. Publication year 2017 Sample Breast cancer cells Sample name 67NR Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK -
3 Experiment ID 1052 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry Western blotting PubMed ID 29115712    Organism Mus musculus Experiment description Proteomic Profiling of Exosomes Secreted by Breast Cancer Cells with Varying Metastatic Potential. Authors Gangoda L, Liem M, Ang CS, Keerthikumar S, Adda CG, Parker BS, Mathivanan S. Journal name Proteomics. Publication year 2017 Sample Breast cancer cells Sample name 66cl4 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK -
4 Experiment ID 1053 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry Western blotting PubMed ID 29115712    Organism Mus musculus Experiment description Proteomic Profiling of Exosomes Secreted by Breast Cancer Cells with Varying Metastatic Potential. Authors Gangoda L, Liem M, Ang CS, Keerthikumar S, Adda CG, Parker BS, Mathivanan S. Journal name Proteomics. Publication year 2017 Sample Breast cancer cells Sample name 4T1 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK -
5 Experiment ID 1054 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry Western blotting PubMed ID 29115712    Organism Mus musculus Experiment description Proteomic Profiling of Exosomes Secreted by Breast Cancer Cells with Varying Metastatic Potential. Authors Gangoda L, Liem M, Ang CS, Keerthikumar S, Adda CG, Parker BS, Mathivanan S. Journal name Proteomics. Publication year 2017 Sample Breast cancer cells Sample name 4T1.2 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK -
6 Experiment ID 1966 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 35915084    Organism Mus musculus Experiment description Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Authors Xie F, Zhou X, Su P, Li H, Tu Y, Du J, Pan C, Wei X, Zheng M, Jin K, Miao L, Wang C, Meng X, van Dam H, Ten Dijke P, Zhang L, Zhou F. Journal name Nat Commun Publication year 2022 Sample Breast cancer cells Sample name 4T07 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
7 Experiment ID 1967 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 35915084    Organism Mus musculus Experiment description Breast cancer cell-derived extracellular vesicles promote CD8+ T cell exhaustion via TGF-β type II receptor signaling Authors Xie F, Zhou X, Su P, Li H, Tu Y, Du J, Pan C, Wei X, Zheng M, Jin K, Miao L, Wang C, Meng X, van Dam H, Ten Dijke P, Zhang L, Zhou F. Journal name Nat Commun Publication year 2022 Sample Breast cancer cells Sample name 4T1 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectometry Immuno-EM Flow cytometry ELISA EV-TRACK -
8 Experiment ID 2857 Identified molecule protein Extracellular vesicle type Small extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 33579909    Organism Mus musculus Experiment description Sulfisoxazole does not inhibit the secretion of small extracellular vesicles Authors Fonseka P, Chitti SV, Sanwlani R, Mathivanan S. Journal name Nat Commun Publication year 2021 Sample Breast cancer cells Sample name 4T1 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
9 Experiment ID 2858 Identified molecule protein Extracellular vesicle type Small extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 33579909    Organism Mus musculus Experiment description Sulfisoxazole does not inhibit the secretion of small extracellular vesicles Authors Fonseka P, Chitti SV, Sanwlani R, Mathivanan S. Journal name Nat Commun Publication year 2021 Sample Breast cancer cells Sample name 4T1 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
10 Experiment ID 2859 Identified molecule protein Extracellular vesicle type Small extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 33579909    Organism Mus musculus Experiment description Sulfisoxazole does not inhibit the secretion of small extracellular vesicles Authors Fonseka P, Chitti SV, Sanwlani R, Mathivanan S. Journal name Nat Commun Publication year 2021 Sample Breast cancer cells Sample name 4T1 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
11 Experiment ID 2860 Identified molecule protein Extracellular vesicle type Small extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 33579909    Organism Mus musculus Experiment description Sulfisoxazole does not inhibit the secretion of small extracellular vesicles Authors Fonseka P, Chitti SV, Sanwlani R, Mathivanan S. Journal name Nat Commun Publication year 2021 Sample Breast cancer cells Sample name 4T1 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
12 Experiment ID 2861 Identified molecule protein Extracellular vesicle type Small extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 33579909    Organism Mus musculus Experiment description Sulfisoxazole does not inhibit the secretion of small extracellular vesicles Authors Fonseka P, Chitti SV, Sanwlani R, Mathivanan S. Journal name Nat Commun Publication year 2021 Sample Breast cancer cells Sample name 4T1 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -