Gene description for A2M
Gene name	alpha-2-macroglobulin
Gene symbol	A2M
Other names/aliases	A2MD CPAMD5 FWP007 S863-7
Species	Homo sapiens
Experiment description of studies that identified A2M in Synovial fluid
1 Experiment ID 62 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 17133577    Organism Mus musculus Experiment description Association of citrullinated proteins with synovial exosomes. Authors Skriner K, Adolph K, Jungblut PR, Burmester GR Journal name AR Publication year 2006 Sample Synovial fluid Sample name Synovial fluid - rheumatoid arthritis Isolation/purification methods Differential centrifugation Sucrose density gradient Flotation density - Molecules identified in the study Protein Methods used in the study Immunoelectron microscopy Mass spectrometry [MALDI TOF] Western blotting EV-TRACK -
2 Experiment ID 61 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 17133577    Organism Mus musculus Experiment description Association of citrullinated proteins with synovial exosomes. Authors Skriner K, Adolph K, Jungblut PR, Burmester GR Journal name AR Publication year 2006 Sample Synovial fluid Sample name Synovial fluid - osteoarthritis and reactive arthritis Isolation/purification methods Differential centrifugation Sucrose density gradient Flotation density - Molecules identified in the study Protein Methods used in the study Immunoelectron microscopy Mass spectrometry [MALDI TOF] Western blotting EV-TRACK -
3 Experiment ID 1009 Identified molecule protein Extracellular vesicle type Microvesicles MISEV EVs Identification method Mass spectrometry PubMed ID 23185418    Organism Homo sapiens Experiment description Improved flow cytometric assessment reveals distinct microvesicle (cell-derived microparticle) signatures in joint diseases. Authors Gyö B, Szabó, TuriáL, Wright M, Herczeg P, Léczi Z, Kittel A, PolgáA, TóK, Déalvi B, ZelenáG, Böz I, Carr B, Nagy G, Véy K, Gay S, Falus A, BuzáEI. Journal name PLoS One. Publication year 2012 Sample Synovial fluid Sample name synovial fluid - patient with osteoarthritis (OA) Isolation/purification methods Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry FACS EV-TRACK EV120104: EV-METRIC:29%
4 Experiment ID 1010 Identified molecule protein Extracellular vesicle type Microvesicles MISEV EVs Identification method Mass spectrometry PubMed ID 23185418    Organism Homo sapiens Experiment description Improved flow cytometric assessment reveals distinct microvesicle (cell-derived microparticle) signatures in joint diseases. Authors Gyö B, Szabó, TuriáL, Wright M, Herczeg P, Léczi Z, Kittel A, PolgáA, TóK, Déalvi B, ZelenáG, Böz I, Carr B, Nagy G, Véy K, Gay S, Falus A, BuzáEI. Journal name PLoS One. Publication year 2012 Sample Synovial fluid Sample name synovial fluid - patient with rheumatoid arthritis (RA) Isolation/purification methods Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry FACS EV-TRACK EV120104: EV-METRIC:29%
5 Experiment ID 1011 Identified molecule protein Extracellular vesicle type Microvesicles MISEV EVs Identification method Mass spectrometry PubMed ID 23185418    Organism Homo sapiens Experiment description Improved flow cytometric assessment reveals distinct microvesicle (cell-derived microparticle) signatures in joint diseases. Authors Gyö B, Szabó, TuriáL, Wright M, Herczeg P, Léczi Z, Kittel A, PolgáA, TóK, Déalvi B, ZelenáG, Böz I, Carr B, Nagy G, Véy K, Gay S, Falus A, BuzáEI. Journal name PLoS One. Publication year 2012 Sample Synovial fluid Sample name synovial fluid - patient with juvenile idiopathic arthritis (JIA) Isolation/purification methods Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry FACS EV-TRACK EV120104: EV-METRIC:29%