Gene description for ERBB2
Gene name	erb-b2 receptor tyrosine kinase 2
Gene symbol	ERBB2
Other names/aliases	CD340 HER-2 HER-2/neu HER2 MLN 19 MLN-19 NEU NGL TKR1 VSCN2 c-ERB-2 c-ERB2 p185(erbB2)
Species	Homo sapiens
Experiment description of studies that identified ERBB2 in Ascites
1 Experiment ID 56 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Western blotting PubMed ID 12147373    Organism Homo sapiens Experiment description Malignant effusions and immunogenic tumour-derived exosomes. Authors Andre F, Schartz NE, Movassagh M, Flament C, Pautier P, Morice P, Pomel C, Lhomme C, Escudier B, Le Chevalier T, Tursz T, Amigorena S, Raposo G, Angevin E, Zitvogel L Journal name LANCET Publication year 2002 Sample Ascites Sample name Malignant ascites Isolation/purification methods Differential centrifugation Sucrose density gradient Flotation density 1.14-1.18 g/mL Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
2 Experiment ID 238 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Dot blot PubMed ID 21293856    Organism Homo sapiens Experiment description Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC Authors Battke C, Ruiss R, Welsch U, Wimberger P, Lang S, Jochum S, Zeidler R Journal name Cancer Immunol Immunother Publication year 2011 Sample Ascites Sample name Malignant ascites - Ovarian cancer Isolation/purification methods Differential centrifugation Filtration Ultrafiltration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.17 g/mL Molecules identified in the study Protein Methods used in the study Dot blot EV-TRACK EV110080: EV-METRIC:14%, 14%, 38%