Gene description for F3
Gene name coagulation factor III, tissue factor
Gene symbol F3
Other names/aliases CD142
TF
TFA
Species Homo sapiens
 Experiment description of studies that identified F3 in Plasma

1
Experiment ID222
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles
MISEVEVs
Identification method Immunoelectron microscopy
FACS
Western blotting
PubMed ID 12514112   
OrganismHomo sapiens
Experiment descriptionIntravascular tissue factor initiates coagulation via circulating microvesicles and platelets
AuthorsMüI, Klocke A, Alex M, Kotzsch M, Luther T, Morgenstern E, Zieseniss S, Zahler S, Preissner K, Engelmann B
Journal name FASEB J
Publication year2003
SamplePlasma
Sample namePlasma - Normal
Isolation/purification methodsDifferential centrifugation
FACS
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyImmunoelectron microscopy
FACS
Western blotting
EV-TRACK -

2
Experiment ID236
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
MISEVEVs
Identification method FACS
PubMed ID 10648405   
OrganismHomo sapiens
Experiment descriptionCellular origin and procoagulant properties of microparticles in meningococcal sepsis
AuthorsNieuwland R, Berckmans RJ, McGregor S, Bö AN, Romijn FP, Westendorp RG, Hack CE, Sturk A
Journal name Blood
Publication year2000
SamplePlasma
Sample namePlasma - Meningococcal sepsis - Nonsurvived
Isolation/purification methodsDifferential centrifugation
FACS
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyFACS
EV-TRACK -

3
Experiment ID247
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles
MISEVEVs
Identification method Western blotting
PubMed ID 15741221   
OrganismHomo sapiens
Experiment descriptionTissue-factor-bearing microvesicles arise from lipid rafts and fuse with activated platelets to initiate coagulation
AuthorsDel Conde I, Shrimpton CN, Thiagarajan P, Ló JA
Journal name Blood
Publication year2005
SamplePlasma
Sample namePlasma - Normal
Isolation/purification methodsDifferential centrifugation
Immunobeads (TF)
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

4
Experiment ID261
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
MISEVEVs
Identification method FACS
PubMed ID 12805058   
OrganismHomo sapiens
Experiment descriptionSickle blood contains tissue factor-positive microparticles derived from endothelial cells and monocytes
AuthorsShet AS, Aras O, Gupta K, Hass MJ, Rausch DJ, Saba N, Koopmeiners L, Key NS, Hebbel RP.
Journal name Blood
Publication year2003
SamplePlasma
Sample namePlasma - Sickle cell patients - Crisis
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
FACS
Flotation density-
Molecules identified in the studyProtein
Lipids
Methods used in the studyFACS
Annexin V-FITC
EV-TRACK -

5
Experiment ID262
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
MISEVEVs
Identification method FACS
PubMed ID 12805058   
OrganismHomo sapiens
Experiment descriptionSickle blood contains tissue factor-positive microparticles derived from endothelial cells and monocytes
AuthorsShet AS, Aras O, Gupta K, Hass MJ, Rausch DJ, Saba N, Koopmeiners L, Key NS, Hebbel RP.
Journal name Blood
Publication year2003
SamplePlasma
Sample namePlasma - Sickle cell patients - Steady state
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
FACS
Flotation density-
Molecules identified in the studyProtein
Lipids
Methods used in the studyFACS
Annexin V-FITC
EV-TRACK -

6
Experiment ID263
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
MISEVEVs
Identification method FACS
PubMed ID 12805058   
OrganismHomo sapiens
Experiment descriptionSickle blood contains tissue factor-positive microparticles derived from endothelial cells and monocytes
AuthorsShet AS, Aras O, Gupta K, Hass MJ, Rausch DJ, Saba N, Koopmeiners L, Key NS, Hebbel RP.
Journal name Blood
Publication year2003
SamplePlasma
Sample namePlasma - Normal
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
FACS
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyFACS
EV-TRACK -

7
Experiment ID286
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
MISEVEVs
Identification method FACS
PubMed ID 12417540   
OrganismHomo sapiens
Experiment descriptionElevated numbers of tissue-factor exposing microparticles correlate with components of the metabolic syndrome in uncomplicated type 2 diabetes mellitus
AuthorsDiamant M, Nieuwland R, Pablo RF, Sturk A, Smit JW, Radder JK
Journal name Circulation
Publication year2002
SamplePlasma
Sample namePlasma - Type 2 diabetes
Isolation/purification methodsDifferential centrifugation
FACS
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyFACS
EV-TRACK -

8
Experiment ID287
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
MISEVEVs
Identification method FACS
PubMed ID 12417540   
OrganismHomo sapiens
Experiment descriptionElevated numbers of tissue-factor exposing microparticles correlate with components of the metabolic syndrome in uncomplicated type 2 diabetes mellitus
AuthorsDiamant M, Nieuwland R, Pablo RF, Sturk A, Smit JW, Radder JK
Journal name Circulation
Publication year2002
SamplePlasma
Sample namePlasma - Normal
Isolation/purification methodsDifferential centrifugation
FACS
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyFACS
EV-TRACK -

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