Gene description for Tsg101
Gene name	tumor susceptibility gene 101
Gene symbol	Tsg101
Other names/aliases	CC2
Species	Mus musculus
Experiment description of studies that identified Tsg101 in Lung cancer cells
1 Experiment ID 1912 Identified molecule protein Extracellular vesicle type Exosomes MISEV Small EVs Identification method Western blotting PubMed ID 36270983    Organism Mus musculus Experiment description NLRP6 is required for cancer-derived exosome-modified macrophage M2 polarization and promotes metastasis in small cell lung cancer Authors Rao X, Zhou X, Wang G, Jie X, Xing B, Xu Y, Chen Y, Li J, Zhu K, Wu Z, Wu G, Wu C, Zhou R. Journal name Cell Death Dis Publication year 2022 Sample Lung cancer cells Sample name Small cell lung cancer (SCLC) Isolation/purification methods Centrifugation Exosome Isolation Reagent Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
2 Experiment ID 2890 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Western blotting PubMed ID 28928431    Organism Mus musculus Experiment description Tumor induces muscle wasting in mice through releasing extracellular Hsp70 and Hsp90 Authors Zhang G, Liu Z, Ding H, Zhou Y, Doan HA, Sin KWT, Zhu ZJ, Flores R, Wen Y, Gong X, Liu Q, Li YP. Journal name Nat Commun Publication year 2017 Sample Lung cancer cells Sample name LLC Isolation/purification methods Centrifugal ultrafiltration ExoQuick Kit Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
3 Experiment ID 2891 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Western blotting PubMed ID 28928431    Organism Mus musculus Experiment description Tumor induces muscle wasting in mice through releasing extracellular Hsp70 and Hsp90 Authors Zhang G, Liu Z, Ding H, Zhou Y, Doan HA, Sin KWT, Zhu ZJ, Flores R, Wen Y, Gong X, Liu Q, Li YP. Journal name Nat Commun Publication year 2017 Sample Lung cancer cells Sample name LLC - immunoprecipitation IgG control supernatant Isolation/purification methods Centrifugal ultrafiltration ExoQuick Kit Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
4 Experiment ID 2892 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Western blotting PubMed ID 28928431    Organism Mus musculus Experiment description Tumor induces muscle wasting in mice through releasing extracellular Hsp70 and Hsp90 Authors Zhang G, Liu Z, Ding H, Zhou Y, Doan HA, Sin KWT, Zhu ZJ, Flores R, Wen Y, Gong X, Liu Q, Li YP. Journal name Nat Commun Publication year 2017 Sample Lung cancer cells Sample name LLC - immunoprecipitation of CD9 precipitated pellet Isolation/purification methods Centrifugal ultrafiltration ExoQuick Kit Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
5 Experiment ID 3372 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Western blotting PubMed ID 33510128    Organism Mus musculus Experiment description Extracellular vesicles-released parathyroid hormone-related protein from Lewis lung carcinoma induces lipolysis and adipose tissue browning in cancer cachexia Authors Hu W, Xiong H, Ru Z, Zhao Y, Zhou Y, Xie K, Xiao W, Xiong Z, Wang C, Yuan C, Shi J, Du Q, Zhang X, Yang H. Journal name Cell Death Dis Publication year 2021 Sample Lung cancer cells Sample name LLC Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
6 Experiment ID 3377 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Western blotting PubMed ID 36581870    Organism Mus musculus Experiment description Exosomal IL-8 derived from Lung Cancer and Colon Cancer cells induced adipocyte atrophy via NF-κB signaling pathway Authors Xiong H, Ye J, Xie K, Hu W, Xu N, Yang H. Journal name Lipids Health Dis Publication year 2022 Sample Lung cancer cells Sample name LLC Isolation/purification methods Differential centrifugation Ultracentrifugation Qiagen Exosome Purification Kit Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -