Gene description for Tsg101
Gene name tumor susceptibility gene 101
Gene symbol Tsg101
Other names/aliases CC2
Species Mus musculus
 Experiment description of studies that identified Tsg101 in Macrophage

1
Experiment ID523
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Mass spectrometry
PubMed ID 23658846   
OrganismMus musculus
Experiment descriptionImmunomodulatory impact of leishmania-induced macrophage exosomes: a comparative proteomic and functional analysis.
AuthorsHassani K, Olivier M.
Journal name PLoS Negl Trop Dis
Publication year2013
SampleMacrophage
Sample nameLeishmania-infected-Macrophage (J774A.1)
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV130144: EV-METRIC:0%, 33%

2
Experiment ID524
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Mass spectrometry
PubMed ID 23658846   
OrganismMus musculus
Experiment descriptionImmunomodulatory impact of leishmania-induced macrophage exosomes: a comparative proteomic and functional analysis.
AuthorsHassani K, Olivier M.
Journal name PLoS Negl Trop Dis
Publication year2013
SampleMacrophage
Sample nameLPS-treated-Macrophage (J774A.1)
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV130144: EV-METRIC:0%, 33%

3
Experiment ID525
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Mass spectrometry
PubMed ID 23658846   
OrganismMus musculus
Experiment descriptionImmunomodulatory impact of leishmania-induced macrophage exosomes: a comparative proteomic and functional analysis.
AuthorsHassani K, Olivier M.
Journal name PLoS Negl Trop Dis
Publication year2013
SampleMacrophage
Sample nameNormal-Macrophage (J774A.1)
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV130144: EV-METRIC:0%, 33%

4
Experiment ID2143
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36658400   
OrganismMus musculus
Experiment descriptionHumoral regulation of iron metabolism by extracellular vesicles drives antibacterial response
AuthorsKuang H, Dou G, Cheng L, Wang X, Xu H, Liu X, Ding F, Yang X, Liu S, Bao L, Liu H, Liu Y, Li B, Jin Y, Liu S.
Journal name Nat Metab
Publication year2023
SampleMacrophage
Sample nameBMDM - S. typhimurium infected
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

5
Experiment ID2143
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36658400   
OrganismMus musculus
Experiment descriptionHumoral regulation of iron metabolism by extracellular vesicles drives antibacterial response
AuthorsKuang H, Dou G, Cheng L, Wang X, Xu H, Liu X, Ding F, Yang X, Liu S, Bao L, Liu H, Liu Y, Li B, Jin Y, Liu S.
Journal name Nat Metab
Publication year2023
SampleMacrophage
Sample nameBMDM - S. typhimurium infected
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

6
Experiment ID2143
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36658400   
OrganismMus musculus
Experiment descriptionHumoral regulation of iron metabolism by extracellular vesicles drives antibacterial response
AuthorsKuang H, Dou G, Cheng L, Wang X, Xu H, Liu X, Ding F, Yang X, Liu S, Bao L, Liu H, Liu Y, Li B, Jin Y, Liu S.
Journal name Nat Metab
Publication year2023
SampleMacrophage
Sample nameBMDM - S. typhimurium infected
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

7
Experiment ID2143
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36658400   
OrganismMus musculus
Experiment descriptionHumoral regulation of iron metabolism by extracellular vesicles drives antibacterial response
AuthorsKuang H, Dou G, Cheng L, Wang X, Xu H, Liu X, Ding F, Yang X, Liu S, Bao L, Liu H, Liu Y, Li B, Jin Y, Liu S.
Journal name Nat Metab
Publication year2023
SampleMacrophage
Sample nameBMDM - S. typhimurium infected
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

8
Experiment ID2144
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36658400   
OrganismMus musculus
Experiment descriptionHumoral regulation of iron metabolism by extracellular vesicles drives antibacterial response
AuthorsKuang H, Dou G, Cheng L, Wang X, Xu H, Liu X, Ding F, Yang X, Liu S, Bao L, Liu H, Liu Y, Li B, Jin Y, Liu S.
Journal name Nat Metab
Publication year2023
SampleMacrophage
Sample nameBMDM - S. typhimurium infected
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

9
Experiment ID2144
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36658400   
OrganismMus musculus
Experiment descriptionHumoral regulation of iron metabolism by extracellular vesicles drives antibacterial response
AuthorsKuang H, Dou G, Cheng L, Wang X, Xu H, Liu X, Ding F, Yang X, Liu S, Bao L, Liu H, Liu Y, Li B, Jin Y, Liu S.
Journal name Nat Metab
Publication year2023
SampleMacrophage
Sample nameBMDM - S. typhimurium infected
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

10
Experiment ID2144
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36658400   
OrganismMus musculus
Experiment descriptionHumoral regulation of iron metabolism by extracellular vesicles drives antibacterial response
AuthorsKuang H, Dou G, Cheng L, Wang X, Xu H, Liu X, Ding F, Yang X, Liu S, Bao L, Liu H, Liu Y, Li B, Jin Y, Liu S.
Journal name Nat Metab
Publication year2023
SampleMacrophage
Sample nameBMDM - S. typhimurium infected
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

11
Experiment ID2144
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36658400   
OrganismMus musculus
Experiment descriptionHumoral regulation of iron metabolism by extracellular vesicles drives antibacterial response
AuthorsKuang H, Dou G, Cheng L, Wang X, Xu H, Liu X, Ding F, Yang X, Liu S, Bao L, Liu H, Liu Y, Li B, Jin Y, Liu S.
Journal name Nat Metab
Publication year2023
SampleMacrophage
Sample nameBMDM - S. typhimurium infected
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

12
Experiment ID2145
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36658400   
OrganismMus musculus
Experiment descriptionHumoral regulation of iron metabolism by extracellular vesicles drives antibacterial response
AuthorsKuang H, Dou G, Cheng L, Wang X, Xu H, Liu X, Ding F, Yang X, Liu S, Bao L, Liu H, Liu Y, Li B, Jin Y, Liu S.
Journal name Nat Metab
Publication year2023
SampleMacrophage
Sample nameBMDM - S. typhimurium infected
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

13
Experiment ID2145
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36658400   
OrganismMus musculus
Experiment descriptionHumoral regulation of iron metabolism by extracellular vesicles drives antibacterial response
AuthorsKuang H, Dou G, Cheng L, Wang X, Xu H, Liu X, Ding F, Yang X, Liu S, Bao L, Liu H, Liu Y, Li B, Jin Y, Liu S.
Journal name Nat Metab
Publication year2023
SampleMacrophage
Sample nameBMDM - S. typhimurium infected
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

14
Experiment ID2145
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36658400   
OrganismMus musculus
Experiment descriptionHumoral regulation of iron metabolism by extracellular vesicles drives antibacterial response
AuthorsKuang H, Dou G, Cheng L, Wang X, Xu H, Liu X, Ding F, Yang X, Liu S, Bao L, Liu H, Liu Y, Li B, Jin Y, Liu S.
Journal name Nat Metab
Publication year2023
SampleMacrophage
Sample nameBMDM - S. typhimurium infected
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

15
Experiment ID2145
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36658400   
OrganismMus musculus
Experiment descriptionHumoral regulation of iron metabolism by extracellular vesicles drives antibacterial response
AuthorsKuang H, Dou G, Cheng L, Wang X, Xu H, Liu X, Ding F, Yang X, Liu S, Bao L, Liu H, Liu Y, Li B, Jin Y, Liu S.
Journal name Nat Metab
Publication year2023
SampleMacrophage
Sample nameBMDM - S. typhimurium infected
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

16
Experiment ID2146
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36658400   
OrganismMus musculus
Experiment descriptionHumoral regulation of iron metabolism by extracellular vesicles drives antibacterial response
AuthorsKuang H, Dou G, Cheng L, Wang X, Xu H, Liu X, Ding F, Yang X, Liu S, Bao L, Liu H, Liu Y, Li B, Jin Y, Liu S.
Journal name Nat Metab
Publication year2023
SampleMacrophage
Sample nameBMDM - S. typhimurium infected
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

17
Experiment ID2146
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36658400   
OrganismMus musculus
Experiment descriptionHumoral regulation of iron metabolism by extracellular vesicles drives antibacterial response
AuthorsKuang H, Dou G, Cheng L, Wang X, Xu H, Liu X, Ding F, Yang X, Liu S, Bao L, Liu H, Liu Y, Li B, Jin Y, Liu S.
Journal name Nat Metab
Publication year2023
SampleMacrophage
Sample nameBMDM - S. typhimurium infected
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

18
Experiment ID2146
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36658400   
OrganismMus musculus
Experiment descriptionHumoral regulation of iron metabolism by extracellular vesicles drives antibacterial response
AuthorsKuang H, Dou G, Cheng L, Wang X, Xu H, Liu X, Ding F, Yang X, Liu S, Bao L, Liu H, Liu Y, Li B, Jin Y, Liu S.
Journal name Nat Metab
Publication year2023
SampleMacrophage
Sample nameBMDM - S. typhimurium infected
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

19
Experiment ID2146
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 36658400   
OrganismMus musculus
Experiment descriptionHumoral regulation of iron metabolism by extracellular vesicles drives antibacterial response
AuthorsKuang H, Dou G, Cheng L, Wang X, Xu H, Liu X, Ding F, Yang X, Liu S, Bao L, Liu H, Liu Y, Li B, Jin Y, Liu S.
Journal name Nat Metab
Publication year2023
SampleMacrophage
Sample nameBMDM - S. typhimurium infected
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

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