Gene description for ALPP
Gene name	alkaline phosphatase, placental
Gene symbol	ALPP
Other names/aliases	ALP ALPI IAP PALP PLAP PLAP-1
Species	Homo sapiens
Experiment description of studies that identified ALPP in Plasma
1 Experiment ID 43 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Western blotting PubMed ID 17076679    Organism Homo sapiens Experiment description Specific isolation of placenta-derived exosomes from the circulation of pregnant women and their immunoregulatory consequences. Authors Sabapatha A, Gercel-Taylor C, Taylor DD Journal name AJRI Publication year 2006 Sample Plasma Sample name Plasma - Pregnant and not-pregnant women Isolation/purification methods Size exclusion chromatography Ultracentrifugation Immunobeads (CD3, CD19, CD56, CD83, PLAP) Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
2 Experiment ID 1079 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method ELISA PubMed ID 25104112    Organism Homo sapiens Experiment description Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. Authors Sarker S, Scholz-Romero K, Perez A, Illanes SE, Mitchell MD, Rice GE, Salomon C. Journal name J Transl Med Publication year 2014 Sample Plasma Sample name Healthy pregnant women (week 6) Isolation/purification methods Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation Flotation density 1.12-1.19 g/mL Molecules identified in the study Protein Methods used in the study ELISA EV-TRACK EV140094: EV-METRIC:56%
3 Experiment ID 1080 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method ELISA PubMed ID 25104112    Organism Homo sapiens Experiment description Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. Authors Sarker S, Scholz-Romero K, Perez A, Illanes SE, Mitchell MD, Rice GE, Salomon C. Journal name J Transl Med Publication year 2014 Sample Plasma Sample name Healthy pregnant women (week 7) Isolation/purification methods Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation Flotation density 1.12-1.19 g/mL Molecules identified in the study Protein Methods used in the study ELISA EV-TRACK EV140094: EV-METRIC:56%
4 Experiment ID 1081 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method ELISA PubMed ID 25104112    Organism Homo sapiens Experiment description Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. Authors Sarker S, Scholz-Romero K, Perez A, Illanes SE, Mitchell MD, Rice GE, Salomon C. Journal name J Transl Med Publication year 2014 Sample Plasma Sample name Healthy pregnant women (week 8) Isolation/purification methods Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation Flotation density 1.12-1.19 g/mL Molecules identified in the study Protein Methods used in the study ELISA EV-TRACK EV140094: EV-METRIC:56%
5 Experiment ID 1082 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method ELISA PubMed ID 25104112    Organism Homo sapiens Experiment description Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. Authors Sarker S, Scholz-Romero K, Perez A, Illanes SE, Mitchell MD, Rice GE, Salomon C. Journal name J Transl Med Publication year 2014 Sample Plasma Sample name Healthy pregnant women (week 9) Isolation/purification methods Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation Flotation density 1.12-1.19 g/mL Molecules identified in the study Protein Methods used in the study ELISA EV-TRACK EV140094: EV-METRIC:56%
6 Experiment ID 1083 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method ELISA PubMed ID 25104112    Organism Homo sapiens Experiment description Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. Authors Sarker S, Scholz-Romero K, Perez A, Illanes SE, Mitchell MD, Rice GE, Salomon C. Journal name J Transl Med Publication year 2014 Sample Plasma Sample name Healthy pregnant women (week 10) Isolation/purification methods Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation Flotation density 1.12-1.19 g/mL Molecules identified in the study Protein Methods used in the study ELISA EV-TRACK EV140094: EV-METRIC:56%
7 Experiment ID 1084 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method ELISA PubMed ID 25104112    Organism Homo sapiens Experiment description Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. Authors Sarker S, Scholz-Romero K, Perez A, Illanes SE, Mitchell MD, Rice GE, Salomon C. Journal name J Transl Med Publication year 2014 Sample Plasma Sample name Healthy pregnant women (week 11) Isolation/purification methods Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation Flotation density 1.12-1.19 g/mL Molecules identified in the study Protein Methods used in the study ELISA EV-TRACK EV140094: EV-METRIC:56%
8 Experiment ID 1085 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method ELISA PubMed ID 25104112    Organism Homo sapiens Experiment description Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy. Authors Sarker S, Scholz-Romero K, Perez A, Illanes SE, Mitchell MD, Rice GE, Salomon C. Journal name J Transl Med Publication year 2014 Sample Plasma Sample name Healthy pregnant women (week 12) Isolation/purification methods Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation Flotation density 1.12-1.19 g/mL Molecules identified in the study Protein Methods used in the study ELISA EV-TRACK EV140094: EV-METRIC:56%