Gene description for CLIC4 |
Gene name |
chloride intracellular channel 4 |
Gene symbol |
CLIC4 |
Other names/aliases |
CLIC4L H1 MTCLIC huH1 p64H1 |
Species |
Homo sapiens |
Experiment description of studies that identified CLIC4 in Urine |
1
|
Experiment ID | 13 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
15326289
|
Organism | Homo sapiens |
Experiment description | Identification and proteomic profiling of exosomes in human urine. |
Authors | Pisitkun T, Shen RF, Knepper MA |
Journal name |
PNAS
|
Publication year | 2004 |
Sample | Urine |
Sample name | Urine - Normal |
Isolation/purification methods | Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LCQ DECA XP] Western blotting |
EV-TRACK |
-
|
|
|
2
|
Experiment ID | 63 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
19056867
|
Organism | Homo sapiens |
Experiment description | Large-scale proteomics and phosphoproteomics of urinary exosomes. |
Authors | Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA |
Journal name |
JASN
|
Publication year | 2009 |
Sample | Urine |
Sample name | Urine - Normal |
Isolation/purification methods | Differential centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [LTQ] Western blotting |
EV-TRACK |
-
|
|
|
3
|
Experiment ID | 382 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
18373357
|
Organism | Homo sapiens |
Experiment description | Isolation and identification of potential urinary microparticle biomarkers of bladder cancer. |
Authors | Smalley DM, Sheman NE, Nelson K, Theodorescu D. |
Journal name |
J Proteome Res
|
Publication year | 2008 |
Sample | Urine |
Sample name | Normal donors-Urine |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
4
|
Experiment ID | 383 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
18373357
|
Organism | Homo sapiens |
Experiment description | Isolation and identification of potential urinary microparticle biomarkers of bladder cancer. |
Authors | Smalley DM, Sheman NE, Nelson K, Theodorescu D. |
Journal name |
J Proteome Res
|
Publication year | 2008 |
Sample | Urine |
Sample name | Patients of bladder cancer-Urine |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
5
|
Experiment ID | 390 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Membrane particles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
19158352
|
Organism | Homo sapiens |
Experiment description | Characterization of PKD protein-positive exosome-like vesicles. |
Authors | Hogan MC, Manganelli L, Woollard JR, Masyuk AI, Masyuk TV, Tammachote R, Huang BQ, Leontovich AA, Beito TG, Madden BJ, Charlesworth MC, Torres VE, LaRusso NF, Harris PC, Ward CJ. |
Journal name |
J Am Soc Nephrol
|
Publication year | 2009 |
Sample | Urine |
Sample name | Patients of autosomal recessive polycystic kidney disease-Urine |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
6
|
Experiment ID | 429 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
21595033
|
Organism | Homo sapiens |
Experiment description | Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy. |
Authors | Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC. |
Journal name |
Proteomics
|
Publication year | 2011 |
Sample | Urine |
Sample name | Normal donors-Urine |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV110019: EV-METRIC:44%
|
|
|
7
|
Experiment ID | 430 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
21595033
|
Organism | Homo sapiens |
Experiment description | Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy. |
Authors | Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC. |
Journal name |
Proteomics
|
Publication year | 2011 |
Sample | Urine |
Sample name | Patients of basement membrane nephropathy-Urine |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV110019: EV-METRIC:44%
|
|
|
8
|
Experiment ID | 431 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
21595033
|
Organism | Homo sapiens |
Experiment description | Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy. |
Authors | Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC. |
Journal name |
Proteomics
|
Publication year | 2011 |
Sample | Urine |
Sample name | Patients of early IgA nephropathy-Urine |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV110019: EV-METRIC:44%
|
|
|
9
|
Experiment ID | 437 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Membrane vesicles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
22106071
|
Organism | Homo sapiens |
Experiment description | Proteomic analysis of urine exosomes by multidimensional protein identification technology (MudPIT). |
Authors | Wang Z, Hill S, Luther JM, Hachey DL, Schey KL. |
Journal name |
Proteomics
|
Publication year | 2012 |
Sample | Urine |
Sample name | Normal donors-Urine |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV120168: EV-METRIC:14%
|
|
|
10
|
Experiment ID | 478 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Membrane vesicles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
23082778
|
Organism | Homo sapiens |
Experiment description | Comparative and Targeted Proteomic Analyses of Urinary Microparticles from Bladder Cancer and Hernia Patients. |
Authors | Chen CL, Lai YF, Tang P, Chien KY, Yu JS, Tsai CH, Chen HW, Wu CC, Chung T, Hsu CW, Chen CD, Chang YS, Chang PL, Chen YT. |
Journal name |
J Proteome Res
|
Publication year | 2012 |
Sample | Urine |
Sample name | Patients of bladder cancer-Urine |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV120030: EV-METRIC:33%
|
|
|
11
|
Experiment ID | 479 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Membrane vesicles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
23082778
|
Organism | Homo sapiens |
Experiment description | Comparative and Targeted Proteomic Analyses of Urinary Microparticles from Bladder Cancer and Hernia Patients. |
Authors | Chen CL, Lai YF, Tang P, Chien KY, Yu JS, Tsai CH, Chen HW, Wu CC, Chung T, Hsu CW, Chen CD, Chang YS, Chang PL, Chen YT. |
Journal name |
J Proteome Res
|
Publication year | 2012 |
Sample | Urine |
Sample name | Patients of hernia-Urine |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV120030: EV-METRIC:33%
|
|
|
12
|
Experiment ID | 498 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Membrane vesicles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
23376485
|
Organism | Homo sapiens |
Experiment description | Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. |
Authors | Prunotto M, Farina A, Lane L, Pernin A, Schifferli J, Hochstrasser DF, Lescuyer P, Moll S. |
Journal name |
J Proteomics
|
Publication year | 2013 |
Sample | Urine |
Sample name | Normal-Urine |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130051: EV-METRIC:38%
|
|
|
13
|
Experiment ID | 507 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Nanovesicles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
23511837
|
Organism | Homo sapiens |
Experiment description | Differential protein profiling of renal cell carcinoma urinary exosomes. |
Authors | Raimondo F, Morosi L, Corbetta S, Chinello C, Brambilla P, Della Mina P, Villa A, Albo G, Battaglia C, Bosari S, Magni F, Pitto M. |
Journal name |
Mol Biosyst
|
Publication year | 2013 |
Sample | Urine |
Sample name | Normal-Urine |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130016: EV-METRIC:44%
|
|
|
14
|
Experiment ID | 508 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Nanovesicles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
23511837
|
Organism | Homo sapiens |
Experiment description | Differential protein profiling of renal cell carcinoma urinary exosomes. |
Authors | Raimondo F, Morosi L, Corbetta S, Chinello C, Brambilla P, Della Mina P, Villa A, Albo G, Battaglia C, Bosari S, Magni F, Pitto M. |
Journal name |
Mol Biosyst
|
Publication year | 2013 |
Sample | Urine |
Sample name | Renal cell carcinoma patient-Urine |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130016: EV-METRIC:44%
|
|
|
15
|
Experiment ID | 725 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
25471207
|
Organism | Homo sapiens |
Experiment description | Intraluminal proteome and peptidome of human urinary extracellular vesicles. |
Authors | Liu X, Chinello C, Musante L, Cazzaniga M, Tataruch D, Calzaferri G, James Smith A, De Sio G, Magni F, Zou H, Holthofer H. |
Journal name |
Proteomics Clin Appl.
|
Publication year | 2015 |
Sample | Urine |
Sample name | Normal crude urine- Trypsinized |
Isolation/purification methods | Differential centrifugation Hydrostatic filtration dialysis Ultrafiltration |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV140189: EV-METRIC:25%
|
|
|