Gene description for GP1BA
Gene name glycoprotein Ib platelet subunit alpha
Gene symbol GP1BA
Other names/aliases BDPLT1
BDPLT3
BSS
CD42B
CD42b-alpha
DBPLT3
GP1B
GPIbA
GPIbalpha
VWDP
Species Homo sapiens
 Experiment description of studies that identified GP1BA in Plasma

1
Experiment ID218
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
MISEVEVs
Identification method Immunoaffinity
PubMed ID 10694520   
OrganismHomo sapiens
Experiment descriptionElevated levels of shed membrane microparticles with procoagulant potential in the peripheral circulating blood of patients with acute coronary syndromes
AuthorsMallat Z, Benamer H, Hugel B, Benessiano J, Steg PG, Freyssinet JM, Tedgui A
Journal name Circulation
Publication year2000
SamplePlasma
Sample namePlasma - Stable angina
Isolation/purification methodsImmunoaffinity [Annexin-V]
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyImmunoaffinity
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2
Experiment ID219
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
MISEVEVs
Identification method Immunoaffinity
PubMed ID 10694520   
OrganismHomo sapiens
Experiment descriptionElevated levels of shed membrane microparticles with procoagulant potential in the peripheral circulating blood of patients with acute coronary syndromes
AuthorsMallat Z, Benamer H, Hugel B, Benessiano J, Steg PG, Freyssinet JM, Tedgui A
Journal name Circulation
Publication year2000
SamplePlasma
Sample namePlasma - Acute coronary syndromes
Isolation/purification methodsImmunoaffinity [Annexin-V]
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyImmunoaffinity
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3
Experiment ID220
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
MISEVEVs
Identification method Immunoaffinity
PubMed ID 10694520   
OrganismHomo sapiens
Experiment descriptionElevated levels of shed membrane microparticles with procoagulant potential in the peripheral circulating blood of patients with acute coronary syndromes
AuthorsMallat Z, Benamer H, Hugel B, Benessiano J, Steg PG, Freyssinet JM, Tedgui A
Journal name Circulation
Publication year2000
SamplePlasma
Sample namePlasma - Noncoronary heart disease
Isolation/purification methodsImmunoaffinity [Annexin-V]
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyImmunoaffinity
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4
Experiment ID222
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles
MISEVEVs
Identification method FACS
PubMed ID 12514112   
OrganismHomo sapiens
Experiment descriptionIntravascular tissue factor initiates coagulation via circulating microvesicles and platelets
AuthorsMüI, Klocke A, Alex M, Kotzsch M, Luther T, Morgenstern E, Zieseniss S, Zahler S, Preissner K, Engelmann B
Journal name FASEB J
Publication year2003
SamplePlasma
Sample namePlasma - Normal
Isolation/purification methodsDifferential centrifugation
FACS
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyImmunoelectron microscopy
FACS
Western blotting
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5
Experiment ID227
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
MISEVEVs
Identification method Antibody based methods
PubMed ID 2942561   
OrganismHomo sapiens
Experiment descriptionPlatelet surface glycoproteins. Studies on resting and activated platelets and platelet membrane microparticles in normal subjects, and observations in patients during adult respiratory distress syndrome and cardiac surgery
AuthorsGeorge JN, Pickett EB, Saucerman S, McEver RP, Kunicki TJ, Kieffer N, Newman PJ
Journal name J Clin Invest
Publication year1986
SamplePlasma
Sample namePlasma - Normal
Isolation/purification methodsDifferential centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyAntibody based methods
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6
Experiment ID230
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
MISEVEVs
Identification method FACS
PubMed ID 2294986   
OrganismHomo sapiens
Experiment descriptionDirect detection of activated platelets and platelet-derived microparticles in humans
AuthorsAbrams CS, Ellison N, Budzynski AZ, Shattil SJ
Journal name Blood
Publication year1990
SamplePlasma
Sample namePlasma - Cardiopulmonary bypass
Isolation/purification methodsFACS
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyFACS
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7
Experiment ID231
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
MISEVEVs
Identification method FACS
PubMed ID 2294986   
OrganismHomo sapiens
Experiment descriptionDirect detection of activated platelets and platelet-derived microparticles in humans
AuthorsAbrams CS, Ellison N, Budzynski AZ, Shattil SJ
Journal name Blood
Publication year1990
SamplePlasma
Sample namePlasma - Standardized bleeding time
Isolation/purification methodsFACS
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyFACS
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8
Experiment ID296
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
MISEVEVs
Identification method FACS
PubMed ID 12796750   
OrganismHomo sapiens
Experiment descriptionHigh levels of circulating endothelial microparticles in patients with acute coronary syndromes
AuthorsBernal-Mizrachi L, Jy W, Jimenez JJ, Pastor J, Mauro LM, Horstman LL, de Marchena E, Ahn YS
Journal name Am Heart J
Publication year2003
SamplePlasma
Sample namePlasma - Normal
Isolation/purification methodsDifferential centrifugation
FACS
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyFACS
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9
Experiment ID299
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
MISEVEVs
Identification method FACS
PubMed ID 12796750   
OrganismHomo sapiens
Experiment descriptionHigh levels of circulating endothelial microparticles in patients with acute coronary syndromes
AuthorsBernal-Mizrachi L, Jy W, Jimenez JJ, Pastor J, Mauro LM, Horstman LL, de Marchena E, Ahn YS
Journal name Am Heart J
Publication year2003
SamplePlasma
Sample namePlasma - Myocardial infarction
Isolation/purification methodsDifferential centrifugation
FACS
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyFACS
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10
Experiment ID454
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 22669077   
OrganismHomo sapiens
Experiment descriptionThe proteome of erythrocyte-derived microparticles from plasma: new clues for erythrocyte aging and vesiculation.
AuthorsBosman GJ, Lasonder E, Groenen-Döpp YA, Willekens FL, Werre JM.
Journal name J Proteomics
Publication year2012
SamplePlasma
Sample nameNormal-Blood
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
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11
Experiment ID473
Identified moleculeprotein
Extracellular vesicle typeMicroparticles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 23056467   
OrganismHomo sapiens
Experiment descriptionCause or Effect of Arteriogenesis: Compositional Alterations of Microparticles from CAD Patients Undergoing External Counterpulsation Therapy.
AuthorsAl Kaabi A, Traupe T, Stutz M, Buchs N, Heller M.
Journal name PLoS One
Publication year2012
SamplePlasma
Sample namePatients of external counterpulsation therapy-Blood
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
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12
Experiment ID2329
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 32487994   
OrganismHomo sapiens
Experiment descriptionPlasma-derived extracellular vesicles from Plasmodium vivax patients signal spleen fibroblasts via NF-kB facilitating parasite cytoadherence
AuthorsToda H, Diaz-Varela M, Segui-Barber J, Roobsoong W, Baro B, Garcia-Silva S, Galiano A, Gualdrón-López M, Almeida ACG, Brito MAM, de Melo GC, Aparici-Herraiz I, Castro-Cavadía C, Monteiro WM, Borràs E, Sabidó E, Almeida IC, Chojnacki J, Martinez-Picado J, Calvo M, Armengol P, Carmona-Fonseca J, Yasnot MF, Lauzurica R, Marcilla A, Peinado H, Galinski MR, Lacerda MVG, Sattabongkot J, Fernandez-Becerra C, Del Portillo HA.
Journal name Nat Commun
Publication year2020
SamplePlasma
Sample nameHealthy donors
Isolation/purification methodsCentrifugation
Size exclusion chromatography
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Mass spectrometry
Flow cytometry
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13
Experiment ID2330
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 32487994   
OrganismHomo sapiens
Experiment descriptionPlasma-derived extracellular vesicles from Plasmodium vivax patients signal spleen fibroblasts via NF-kB facilitating parasite cytoadherence
AuthorsToda H, Diaz-Varela M, Segui-Barber J, Roobsoong W, Baro B, Garcia-Silva S, Galiano A, Gualdrón-López M, Almeida ACG, Brito MAM, de Melo GC, Aparici-Herraiz I, Castro-Cavadía C, Monteiro WM, Borràs E, Sabidó E, Almeida IC, Chojnacki J, Martinez-Picado J, Calvo M, Armengol P, Carmona-Fonseca J, Yasnot MF, Lauzurica R, Marcilla A, Peinado H, Galinski MR, Lacerda MVG, Sattabongkot J, Fernandez-Becerra C, Del Portillo HA.
Journal name Nat Commun
Publication year2020
SamplePlasma
Sample namePlasmodium vivax (Malaria) patients
Isolation/purification methodsCentrifugation
Size exclusion chromatography
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Mass spectrometry
Flow cytometry
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14
Experiment ID2433
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 29320704   
OrganismHomo sapiens
Experiment descriptionExtracellular Vesicles Provide a Means for Tissue Crosstalk during Exercise
AuthorsWhitham M, Parker BL, Friedrichsen M, Hingst JR, Hjorth M, Hughes WE, Egan CL, Cron L, Watt KI, Kuchel RP, Jayasooriah N, Estevez E, Petzold T, Suter CM, Gregorevic P, Kiens B, Richter EA, James DE, Wojtaszewski JFP, Febbraio MA.
Journal name Cell Metab
Publication year2018
SamplePlasma
Sample namePlasma
Isolation/purification methodsCentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -

15
Experiment ID2434
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 29320704   
OrganismHomo sapiens
Experiment descriptionExtracellular Vesicles Provide a Means for Tissue Crosstalk during Exercise
AuthorsWhitham M, Parker BL, Friedrichsen M, Hingst JR, Hjorth M, Hughes WE, Egan CL, Cron L, Watt KI, Kuchel RP, Jayasooriah N, Estevez E, Petzold T, Suter CM, Gregorevic P, Kiens B, Richter EA, James DE, Wojtaszewski JFP, Febbraio MA.
Journal name Cell Metab
Publication year2018
SamplePlasma
Sample namePlasma
Isolation/purification methodsCentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -

16
Experiment ID2848
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 35058437   
OrganismHomo sapiens
Experiment descriptionCirculating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2
AuthorsEl-Shennawy L, Hoffmann AD, Dashzeveg NK, McAndrews KM, Mehl PJ, Cornish D, Yu Z, Tokars VL, Nicolaescu V, Tomatsidou A, Mao C, Felicelli CJ, Tsai CF, Ostiguin C, Jia Y, Li L, Furlong K, Wysocki J, Luo X, Ruivo CF, Batlle D, Hope TJ, Shen Y, Chae YK, Zhang H, LeBleu VS, Shi T, Swaminathan S, Luo Y, Missiakas D, Randall GC, Demonbreun AR, Ison MG, Kalluri R, Fang D, Liu H.
Journal name Nat Commun
Publication year2022
SamplePlasma
Sample nameNWL-001 - Lung cancer patient
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Mass spectrometry
EV-TRACK -

17
Experiment ID2849
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 35058437   
OrganismHomo sapiens
Experiment descriptionCirculating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2
AuthorsEl-Shennawy L, Hoffmann AD, Dashzeveg NK, McAndrews KM, Mehl PJ, Cornish D, Yu Z, Tokars VL, Nicolaescu V, Tomatsidou A, Mao C, Felicelli CJ, Tsai CF, Ostiguin C, Jia Y, Li L, Furlong K, Wysocki J, Luo X, Ruivo CF, Batlle D, Hope TJ, Shen Y, Chae YK, Zhang H, LeBleu VS, Shi T, Swaminathan S, Luo Y, Missiakas D, Randall GC, Demonbreun AR, Ison MG, Kalluri R, Fang D, Liu H.
Journal name Nat Commun
Publication year2022
SamplePlasma
Sample nameNWL-004 - Lung cancer patient
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -

18
Experiment ID2850
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 35058437   
OrganismHomo sapiens
Experiment descriptionCirculating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2
AuthorsEl-Shennawy L, Hoffmann AD, Dashzeveg NK, McAndrews KM, Mehl PJ, Cornish D, Yu Z, Tokars VL, Nicolaescu V, Tomatsidou A, Mao C, Felicelli CJ, Tsai CF, Ostiguin C, Jia Y, Li L, Furlong K, Wysocki J, Luo X, Ruivo CF, Batlle D, Hope TJ, Shen Y, Chae YK, Zhang H, LeBleu VS, Shi T, Swaminathan S, Luo Y, Missiakas D, Randall GC, Demonbreun AR, Ison MG, Kalluri R, Fang D, Liu H.
Journal name Nat Commun
Publication year2022
SamplePlasma
Sample nameCSB-012 - COVID-19 patient - convalescent phase
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Mass spectrometry
EV-TRACK -

19
Experiment ID2851
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 35058437   
OrganismHomo sapiens
Experiment descriptionCirculating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2
AuthorsEl-Shennawy L, Hoffmann AD, Dashzeveg NK, McAndrews KM, Mehl PJ, Cornish D, Yu Z, Tokars VL, Nicolaescu V, Tomatsidou A, Mao C, Felicelli CJ, Tsai CF, Ostiguin C, Jia Y, Li L, Furlong K, Wysocki J, Luo X, Ruivo CF, Batlle D, Hope TJ, Shen Y, Chae YK, Zhang H, LeBleu VS, Shi T, Swaminathan S, Luo Y, Missiakas D, Randall GC, Demonbreun AR, Ison MG, Kalluri R, Fang D, Liu H.
Journal name Nat Commun
Publication year2022
SamplePlasma
Sample nameCSB-024 - COVID-19 patient - convalescent phase
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
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