Gene description for ANXA1
Gene name annexin A1
Gene symbol ANXA1
Other names/aliases ANX1
LPC1
Species Homo sapiens
 Experiment description of studies that identified ANXA1 in Serum

1
Experiment ID1504
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 33953168   
OrganismHomo sapiens
Experiment descriptionMastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation
AuthorsKim DK, Bandara G, Cho YE, Komarow HD, Donahue DR, Karim B, Baek MC, Kim HM, Metcalfe DD, Olivera A.
Journal name Nat Commun
Publication year2021
SampleSerum
Sample nameHealthy volunteers - Pooled
Isolation/purification methodsCentrifugation
Filtration
Iodixanol density gradient centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

2
Experiment ID1505
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 33953168   
OrganismHomo sapiens
Experiment descriptionMastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation
AuthorsKim DK, Bandara G, Cho YE, Komarow HD, Donahue DR, Karim B, Baek MC, Kim HM, Metcalfe DD, Olivera A.
Journal name Nat Commun
Publication year2021
SampleSerum
Sample nameSystemic mastocytosis patients - Tryptase <110 ng/mL - Pooled
Isolation/purification methodsCentrifugation
Filtration
Iodixanol density gradient centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

3
Experiment ID1506
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 33953168   
OrganismHomo sapiens
Experiment descriptionMastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation
AuthorsKim DK, Bandara G, Cho YE, Komarow HD, Donahue DR, Karim B, Baek MC, Kim HM, Metcalfe DD, Olivera A.
Journal name Nat Commun
Publication year2021
SampleSerum
Sample nameSystemic mastocytosis patients - Tryptase >110 ng/mL - Pooled
Isolation/purification methodsCentrifugation
Filtration
Iodixanol density gradient centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

4
Experiment ID1507
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 33953168   
OrganismHomo sapiens
Experiment descriptionMastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation
AuthorsKim DK, Bandara G, Cho YE, Komarow HD, Donahue DR, Karim B, Baek MC, Kim HM, Metcalfe DD, Olivera A.
Journal name Nat Commun
Publication year2021
SampleSerum
Sample nameSystemic mastocytosis patients - Fraction 1
Isolation/purification methodsCentrifugation
Filtration
Iodixanol density gradient centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

5
Experiment ID1508
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 33953168   
OrganismHomo sapiens
Experiment descriptionMastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation
AuthorsKim DK, Bandara G, Cho YE, Komarow HD, Donahue DR, Karim B, Baek MC, Kim HM, Metcalfe DD, Olivera A.
Journal name Nat Commun
Publication year2021
SampleSerum
Sample nameSystemic mastocytosis patients - Fraction 2
Isolation/purification methodsCentrifugation
Filtration
Iodixanol density gradient centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

6
Experiment ID1509
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 33953168   
OrganismHomo sapiens
Experiment descriptionMastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation
AuthorsKim DK, Bandara G, Cho YE, Komarow HD, Donahue DR, Karim B, Baek MC, Kim HM, Metcalfe DD, Olivera A.
Journal name Nat Commun
Publication year2021
SampleSerum
Sample nameSystemic mastocytosis patients - Fraction 3
Isolation/purification methodsCentrifugation
Filtration
Iodixanol density gradient centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

7
Experiment ID1510
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 33953168   
OrganismHomo sapiens
Experiment descriptionMastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation
AuthorsKim DK, Bandara G, Cho YE, Komarow HD, Donahue DR, Karim B, Baek MC, Kim HM, Metcalfe DD, Olivera A.
Journal name Nat Commun
Publication year2021
SampleSerum
Sample nameSystemic mastocytosis patients - Fraction 4
Isolation/purification methodsCentrifugation
Filtration
Iodixanol density gradient centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

8
Experiment ID1511
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 33953168   
OrganismHomo sapiens
Experiment descriptionMastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation
AuthorsKim DK, Bandara G, Cho YE, Komarow HD, Donahue DR, Karim B, Baek MC, Kim HM, Metcalfe DD, Olivera A.
Journal name Nat Commun
Publication year2021
SampleSerum
Sample nameSystemic mastocytosis patients - Fraction 5
Isolation/purification methodsCentrifugation
Filtration
Iodixanol density gradient centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

9
Experiment ID1512
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 33953168   
OrganismHomo sapiens
Experiment descriptionMastocytosis-derived extracellular vesicles deliver miR-23a and miR-30a into pre-osteoblasts and prevent osteoblastogenesis and bone formation
AuthorsKim DK, Bandara G, Cho YE, Komarow HD, Donahue DR, Karim B, Baek MC, Kim HM, Metcalfe DD, Olivera A.
Journal name Nat Commun
Publication year2021
SampleSerum
Sample nameSystemic mastocytosis patients - Fraction 6
Isolation/purification methodsCentrifugation
Filtration
Iodixanol density gradient centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

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