Gene description for ANXA2
Gene name annexin A2
Gene symbol ANXA2
Other names/aliases ANX2
ANX2L4
CAL1H
HEL-S-270
LIP2
LPC2
LPC2D
P36
PAP-IV
Species Homo sapiens
 Experiment description of studies that identified ANXA2 in Osteoblasts

1
Experiment ID733
Identified moleculeprotein
Extracellular vesicle typeMatrix vesicles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 25359493   
OrganismHomo sapiens
Experiment descriptionProteomic signatures of extracellular vesicles secreted by nonmineralizing and mineralizing human osteoblasts and stimulation of tumor cell growth.
AuthorsMorhayim J, van de Peppel J, Demmers JA, Kocer G, Nigg AL, van Driel M, Chiba H, van Leeuwen JP.
Journal name FASEB J
Publication year2015
SampleOsteoblasts
Sample nameMOB's- dexamethasone treated
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV140255: EV-METRIC:33%

2
Experiment ID734
Identified moleculeprotein
Extracellular vesicle typeMatrix vesicles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 25359493   
OrganismHomo sapiens
Experiment descriptionProteomic signatures of extracellular vesicles secreted by nonmineralizing and mineralizing human osteoblasts and stimulation of tumor cell growth.
AuthorsMorhayim J, van de Peppel J, Demmers JA, Kocer G, Nigg AL, van Driel M, Chiba H, van Leeuwen JP.
Journal name FASEB J
Publication year2015
SampleOsteoblasts
Sample nameNMOB's- non-dexamethasone-treated
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV140255: EV-METRIC:33%

3
Experiment ID727
Identified moleculeprotein
Extracellular vesicle typeMatrix vesicles
MISEVEVs
Identification method Western blotting
PubMed ID 25359493   
OrganismHomo sapiens
Experiment descriptionProteomic signatures of extracellular vesicles secreted by nonmineralizing and mineralizing human osteoblasts and stimulation of tumor cell growth.
AuthorsMorhayim J, van de Peppel J, Demmers JA, Kocer G, Nigg AL, van Driel M, Chiba H, van Leeuwen JP.
Journal name FASEB J
Publication year2015
SampleOsteoblasts
Sample nameMOB's- dexamethasone treated (day 5)
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK EV140255: EV-METRIC:33%

4
Experiment ID728
Identified moleculeprotein
Extracellular vesicle typeMatrix vesicles
MISEVEVs
Identification method Western blotting
PubMed ID 25359493   
OrganismHomo sapiens
Experiment descriptionProteomic signatures of extracellular vesicles secreted by nonmineralizing and mineralizing human osteoblasts and stimulation of tumor cell growth.
AuthorsMorhayim J, van de Peppel J, Demmers JA, Kocer G, Nigg AL, van Driel M, Chiba H, van Leeuwen JP.
Journal name FASEB J
Publication year2015
SampleOsteoblasts
Sample nameMOB's- dexamethasone-treated (day 12)
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK EV140255: EV-METRIC:33%

5
Experiment ID729
Identified moleculeprotein
Extracellular vesicle typeMatrix vesicles
MISEVEVs
Identification method Western blotting
PubMed ID 25359493   
OrganismHomo sapiens
Experiment descriptionProteomic signatures of extracellular vesicles secreted by nonmineralizing and mineralizing human osteoblasts and stimulation of tumor cell growth.
AuthorsMorhayim J, van de Peppel J, Demmers JA, Kocer G, Nigg AL, van Driel M, Chiba H, van Leeuwen JP.
Journal name FASEB J
Publication year2015
SampleOsteoblasts
Sample nameMOB's- dexamethasone-treated (day 19)
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK EV140255: EV-METRIC:33%

6
Experiment ID730
Identified moleculeprotein
Extracellular vesicle typeMatrix vesicles
MISEVEVs
Identification method Western blotting
PubMed ID 25359493   
OrganismHomo sapiens
Experiment descriptionProteomic signatures of extracellular vesicles secreted by nonmineralizing and mineralizing human osteoblasts and stimulation of tumor cell growth.
AuthorsMorhayim J, van de Peppel J, Demmers JA, Kocer G, Nigg AL, van Driel M, Chiba H, van Leeuwen JP.
Journal name FASEB J
Publication year2015
SampleOsteoblasts
Sample nameNMOB's- non-dexamethasone-treated (day 5)
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK EV140255: EV-METRIC:33%

7
Experiment ID731
Identified moleculeprotein
Extracellular vesicle typeMatrix vesicles
MISEVEVs
Identification method Western blotting
PubMed ID 25359493   
OrganismHomo sapiens
Experiment descriptionProteomic signatures of extracellular vesicles secreted by nonmineralizing and mineralizing human osteoblasts and stimulation of tumor cell growth.
AuthorsMorhayim J, van de Peppel J, Demmers JA, Kocer G, Nigg AL, van Driel M, Chiba H, van Leeuwen JP.
Journal name FASEB J
Publication year2015
SampleOsteoblasts
Sample nameNMOB's- non-dexamethasone-treated (day 12)
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK EV140255: EV-METRIC:33%

8
Experiment ID732
Identified moleculeprotein
Extracellular vesicle typeMatrix vesicles
MISEVEVs
Identification method Western blotting
PubMed ID 25359493   
OrganismHomo sapiens
Experiment descriptionProteomic signatures of extracellular vesicles secreted by nonmineralizing and mineralizing human osteoblasts and stimulation of tumor cell growth.
AuthorsMorhayim J, van de Peppel J, Demmers JA, Kocer G, Nigg AL, van Driel M, Chiba H, van Leeuwen JP.
Journal name FASEB J
Publication year2015
SampleOsteoblasts
Sample nameNMOB's- non-dexamethasone-treated (day 19)
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK EV140255: EV-METRIC:33%

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