Gene description for HLA-DRA
Gene name major histocompatibility complex, class II, DR alpha
Gene symbol HLA-DRA
Other names/aliases HLA-DRA1
Species Homo sapiens
 Experiment description of studies that identified HLA-DRA in Malignant pleural effusions

1
Experiment ID51
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Western blotting
PubMed ID 14975938   
OrganismHomo sapiens
Experiment descriptionProteomic analysis of exosomes isolated from human malignant pleural effusions.
AuthorsBard MP, Hegmans JP, Hemmes A, Luider TM, Willemsen R, Severijnen LA, van Meerbeeck JP, Burgers SA, Hoogsteden HC, Lambrecht BN
Journal name AJRCMB
Publication year2004
SampleMalignant pleural effusions
Sample namePleural Fluid - Breast cancer
Isolation/purification methodsDifferential centrifugation
Sucrose density gradient
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [MALDI TOF]
Western blotting
EV-TRACK -

2
Experiment ID52
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Western blotting
PubMed ID 14975938   
OrganismHomo sapiens
Experiment descriptionProteomic analysis of exosomes isolated from human malignant pleural effusions.
AuthorsBard MP, Hegmans JP, Hemmes A, Luider TM, Willemsen R, Severijnen LA, van Meerbeeck JP, Burgers SA, Hoogsteden HC, Lambrecht BN
Journal name AJRCMB
Publication year2004
SampleMalignant pleural effusions
Sample namePleural Fluid - Lung cancer
Isolation/purification methodsDifferential centrifugation
Sucrose density gradient
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [MALDI TOF]
Western blotting
EV-TRACK -

3
Experiment ID53
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Western blotting
PubMed ID 14975938   
OrganismHomo sapiens
Experiment descriptionProteomic analysis of exosomes isolated from human malignant pleural effusions.
AuthorsBard MP, Hegmans JP, Hemmes A, Luider TM, Willemsen R, Severijnen LA, van Meerbeeck JP, Burgers SA, Hoogsteden HC, Lambrecht BN
Journal name AJRCMB
Publication year2004
SampleMalignant pleural effusions
Sample namePleural Fluid - Mesothelioma
Isolation/purification methodsDifferential centrifugation
Sucrose density gradient
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [MALDI TOF]
Western blotting
EV-TRACK -

4
Experiment ID54
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Western blotting
PubMed ID 14975938   
OrganismHomo sapiens
Experiment descriptionProteomic analysis of exosomes isolated from human malignant pleural effusions.
AuthorsBard MP, Hegmans JP, Hemmes A, Luider TM, Willemsen R, Severijnen LA, van Meerbeeck JP, Burgers SA, Hoogsteden HC, Lambrecht BN
Journal name AJRCMB
Publication year2004
SampleMalignant pleural effusions
Sample namePleural Fluid - Ovarian adenocarcioma
Isolation/purification methodsDifferential centrifugation
Sucrose density gradient
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

5
Experiment ID109
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Western blotting
PubMed ID 21601258   
OrganismHomo sapiens
Experiment descriptionLoss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage.
AuthorsRupp AK, Rupp C, Keller S, Brase JC, Ehehalt R, Fogel M, Moldenhauer G, Marmé, Sün H, Altevogt P.
Journal name GO
Publication year2011
SampleMalignant pleural effusions
Sample namePleural effusions - breast cancer
Isolation/purification methodsDifferential centrifugation
Sucrose density gradient
Immunobeads (EpCAM)
Flotation density-
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
EV-TRACK EV110020: EV-METRIC:13%, 63%, 50%

6
Experiment ID519
Identified moleculeprotein
Extracellular vesicle typeExosomes/Microvesicles/Ectosomes/Microparticles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 23585444   
OrganismHomo sapiens
Experiment descriptionIdentification and characterization of proteins isolated from microvesicles derived from human lung cancer pleural effusions.
AuthorsPark JO, Choi DY, Choi DS, Kim HJ, Kang JW, Jung JH, Lee JH, Kim J, Freeman MR, Lee KY, Gho YS, Kim KP.
Journal name Proteomics
Publication year2013
SampleMalignant pleural effusions
Sample nameNon-small cell lung cancer patient-Lung cancer pleural effusion
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV130049: EV-METRIC:38%

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