Gene description for HLA-DRB5
Gene name	major histocompatibility complex, class II, DR beta 5
Gene symbol	HLA-DRB5
Other names/aliases	DRB5 HLA-DRB5*
Species	Homo sapiens
Experiment description of studies that identified HLA-DRB5 in T cells
1 Experiment ID 18 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method FACS PubMed ID 11907077    Organism Homo sapiens Experiment description TCR activation of human T cells induces the production of exosomes bearing the TCR/CD3/zeta complex. Authors Blanchard N, Lankar D, Faure F, Regnault A, Dumont C, Raposo G, Hivroz C Journal name JIMMU Publication year 2002 Sample T cells Sample name Jurkat T cell blasts Isolation/purification methods Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study FACS EV-TRACK -
2 Experiment ID 245 Identified molecule protein Extracellular vesicle type Microvesicles MISEV EVs Identification method Radioimmunoassay PubMed ID 9126269    Organism Homo sapiens Experiment description Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations Authors Bess JW Jr, Gorelick RJ, Bosche WJ, Henderson LE, Arthur LO Journal name Virology Publication year 1997 Sample T cells Sample name H9 - non infected Isolation/purification methods Differential centrifugation Sucrose density gradient Flotation density 1.08-1.29 g/mL Molecules identified in the study Protein mRNA Methods used in the study Radioimmunoassay EV-TRACK -
3 Experiment ID 252 Identified molecule protein Extracellular vesicle type Microvesicles MISEV EVs Identification method Radioimmunoassay PubMed ID 9126269    Organism Homo sapiens Experiment description Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations Authors Bess JW Jr, Gorelick RJ, Bosche WJ, Henderson LE, Arthur LO Journal name Virology Publication year 1997 Sample T cells Sample name H9 - HIV infected Isolation/purification methods Differential centrifugation Sucrose density gradient Flotation density 1.08-1.29 g/mL Molecules identified in the study Protein Methods used in the study Radioimmunoassay Northern blotting EV-TRACK -
4 Experiment ID 1008 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 23463506    Organism Homo sapiens Experiment description The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes. Authors Perez-Hernandez D, Gutiéez-Váuez C, Jorge I, Ló-MartíS, Ursa A, Sáhez-Madrid F, Váuez J, Yáz-Mó Journal name J Biol Chem. Publication year 2013 Sample T cells Sample name T lymphoblasts Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130110: EV-METRIC:22%