Gene description for Uch
Gene name	Ubiquitin carboxy-terminal hydrolase
Gene symbol	Uch
Other names/aliases	CG4265 DmelCG4265 P35122 UBL UCH UCH-D UCH-D19 UCH-L1 UCHL1 Uch-D Uchl Uchl1 cg4265 dUCH dUch uch uch-D
Species	Drosophila melanogaster
Experiment description of studies that identified Uch in Drosophila S2 cells
1 Experiment ID 471 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 23035643    Organism Drosophila melanogaster Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes. Authors Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP. Journal name Traffic Publication year 2012 Sample Drosophila S2 cells Sample name Normal-Drosophila S2 tub-Wg Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130023: EV-METRIC:33%, 56%
2 Experiment ID 1278 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 22437826    Organism Drosophila melanogaster Experiment description Mechanism of evenness interrupted (Evi)-exosome release at synaptic boutons. Authors Koles K, Nunnari J, Korkut C, Barria R, Brewer C, Li Y, Leszyk J, Zhang B, Budnik V. Journal name J Biol Chem Publication year 2012 Sample Drosophila S2 cells Sample name S2 cells Isolation/purification methods Ultracentrifugation Density gradient centrifugation Flotation density 1.15-1.19 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV120033: EV-METRIC:33%