Gene description for IGFBP3
Gene name insulin like growth factor binding protein 3
Gene symbol IGFBP3
Other names/aliases BP-53
IBP3
Species Homo sapiens
 Experiment description of studies that identified IGFBP3 in Fibroblasts

1
Experiment ID3038
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Western blotting
PubMed ID 33893753   
OrganismHomo sapiens
Experiment descriptionLabel-free quantitative proteomic analysis of extracellular vesicles released from fibroblasts derived from patients with spinal muscular atrophy
AuthorsRoberto J, Poulin KL, Parks RJ, Vacratsis PO.
Journal name Proteomics
Publication year2021
SampleFibroblasts
Sample nameGM03813 - SMA type 2
Isolation/purification methodsCentrifugation
Polyethylene glycol-based precipitation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

2
Experiment ID3039
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Western blotting
PubMed ID 33893753   
OrganismHomo sapiens
Experiment descriptionLabel-free quantitative proteomic analysis of extracellular vesicles released from fibroblasts derived from patients with spinal muscular atrophy
AuthorsRoberto J, Poulin KL, Parks RJ, Vacratsis PO.
Journal name Proteomics
Publication year2021
SampleFibroblasts
Sample nameGM03814 - Normal
Isolation/purification methodsCentrifugation
Polyethylene glycol-based precipitation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

3
Experiment ID3040
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Western blotting
PubMed ID 33893753   
OrganismHomo sapiens
Experiment descriptionLabel-free quantitative proteomic analysis of extracellular vesicles released from fibroblasts derived from patients with spinal muscular atrophy
AuthorsRoberto J, Poulin KL, Parks RJ, Vacratsis PO.
Journal name Proteomics
Publication year2021
SampleFibroblasts
Sample nameAG08498 - Normal
Isolation/purification methodsCentrifugation
Polyethylene glycol-based precipitation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

4
Experiment ID3041
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Western blotting
PubMed ID 33893753   
OrganismHomo sapiens
Experiment descriptionLabel-free quantitative proteomic analysis of extracellular vesicles released from fibroblasts derived from patients with spinal muscular atrophy
AuthorsRoberto J, Poulin KL, Parks RJ, Vacratsis PO.
Journal name Proteomics
Publication year2021
SampleFibroblasts
Sample nameAG07095 - Normal
Isolation/purification methodsCentrifugation
Polyethylene glycol-based precipitation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

5
Experiment ID3042
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Western blotting
PubMed ID 33893753   
OrganismHomo sapiens
Experiment descriptionLabel-free quantitative proteomic analysis of extracellular vesicles released from fibroblasts derived from patients with spinal muscular atrophy
AuthorsRoberto J, Poulin KL, Parks RJ, Vacratsis PO.
Journal name Proteomics
Publication year2021
SampleFibroblasts
Sample nameGM05565 - Normal
Isolation/purification methodsCentrifugation
Polyethylene glycol-based precipitation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

6
Experiment ID3043
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Western blotting
PubMed ID 33893753   
OrganismHomo sapiens
Experiment descriptionLabel-free quantitative proteomic analysis of extracellular vesicles released from fibroblasts derived from patients with spinal muscular atrophy
AuthorsRoberto J, Poulin KL, Parks RJ, Vacratsis PO.
Journal name Proteomics
Publication year2021
SampleFibroblasts
Sample nameGM00232 - SMA type 1
Isolation/purification methodsCentrifugation
Polyethylene glycol-based precipitation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

7
Experiment ID3044
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Western blotting
PubMed ID 33893753   
OrganismHomo sapiens
Experiment descriptionLabel-free quantitative proteomic analysis of extracellular vesicles released from fibroblasts derived from patients with spinal muscular atrophy
AuthorsRoberto J, Poulin KL, Parks RJ, Vacratsis PO.
Journal name Proteomics
Publication year2021
SampleFibroblasts
Sample nameGM22592 - SMA type 2
Isolation/purification methodsCentrifugation
Polyethylene glycol-based precipitation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

8
Experiment ID3036
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 33893753   
OrganismHomo sapiens
Experiment descriptionLabel-free quantitative proteomic analysis of extracellular vesicles released from fibroblasts derived from patients with spinal muscular atrophy
AuthorsRoberto J, Poulin KL, Parks RJ, Vacratsis PO.
Journal name Proteomics
Publication year2021
SampleFibroblasts
Sample nameGM03813 - SMA type 2
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -

9
Experiment ID3037
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 33893753   
OrganismHomo sapiens
Experiment descriptionLabel-free quantitative proteomic analysis of extracellular vesicles released from fibroblasts derived from patients with spinal muscular atrophy
AuthorsRoberto J, Poulin KL, Parks RJ, Vacratsis PO.
Journal name Proteomics
Publication year2021
SampleFibroblasts
Sample nameGM03814 - Normal
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -

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