Gene description for KLK3
Gene name	kallikrein related peptidase 3
Gene symbol	KLK3
Other names/aliases	APS KLK2A1 PSA hK3
Species	Homo sapiens
Experiment description of studies that identified KLK3 in Breast cancer cells
1 Experiment ID 3514 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Thermophoretic aptasensor (TAS) PubMed ID 30948809    Organism Homo sapiens Experiment description Low-cost thermophoretic profiling of extracellular-vesicle surface proteins for the early detection and classification of cancers Authors Liu C, Zhao J, Tian F, Cai L, Zhang W, Feng Q, Chang J, Wan F, Yang Y, Dai B, Cong Y, Ding B, Sun J, Tan W. Journal name Nat Biomed Eng Publication year 2019 Sample Breast cancer cells Sample name MDA-MB-231 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Thermophoretic aptasensor (TAS) EV-TRACK -
2 Experiment ID 3350 Identified molecule protein Extracellular vesicle type Supermeres MISEV EV-like nanoparticles Identification method Mass spectrometry PubMed ID 34887515    Organism Homo sapiens Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Authors Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ. Journal name Nat Cell Biol Publication year 2021 Sample Breast cancer cells Sample name MDA-MB-231 Isolation/purification methods Differential centrifugation Filtration Centrifugal ultrafiltration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry ELISA EV-TRACK -