Gene description for IRS1
Gene name	insulin receptor substrate 1
Gene symbol	IRS1
Other names/aliases	HIRS-1
Species	Homo sapiens
Experiment description of studies that identified IRS1 in Plasma
1 Experiment ID 2130 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method ELISA PubMed ID 36515353    Organism Homo sapiens Experiment description Oral nicotinamide riboside raises NAD+ and lowers biomarkers of neurodegenerative pathology in plasma extracellular vesicles enriched for neuronal origin Authors Vreones M, Mustapic M, Moaddel R, Pucha KA, Lovett J, Seals DR, Kapogiannis D, Martens CR. Journal name Aging Cell Publication year 2023 Sample Plasma Sample name Patient-derived neuronal origin EVs (enriched) Isolation/purification methods ExoQuick Kit Centrifugation Flotation density - Molecules identified in the study Metabolite Protein Methods used in the study Mass spectometry Luciferase assay ELISA EV-TRACK -
2 Experiment ID 2131 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method ELISA PubMed ID 36515353    Organism Homo sapiens Experiment description Oral nicotinamide riboside raises NAD+ and lowers biomarkers of neurodegenerative pathology in plasma extracellular vesicles enriched for neuronal origin Authors Vreones M, Mustapic M, Moaddel R, Pucha KA, Lovett J, Seals DR, Kapogiannis D, Martens CR. Journal name Aging Cell Publication year 2023 Sample Plasma Sample name Patient-derived neuronal origin EVs (enriched) Isolation/purification methods ExoQuick Kit Centrifugation Flotation density - Molecules identified in the study Metabolite Protein Methods used in the study Mass spectometry Luciferase assay ELISA EV-TRACK -
3 Experiment ID 2132 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method ELISA PubMed ID 36515353    Organism Homo sapiens Experiment description Oral nicotinamide riboside raises NAD+ and lowers biomarkers of neurodegenerative pathology in plasma extracellular vesicles enriched for neuronal origin Authors Vreones M, Mustapic M, Moaddel R, Pucha KA, Lovett J, Seals DR, Kapogiannis D, Martens CR. Journal name Aging Cell Publication year 2023 Sample Plasma Sample name Patient-derived neuronal origin EVs (enriched) - responders Isolation/purification methods ExoQuick Kit Centrifugation Flotation density - Molecules identified in the study Metabolite Protein Methods used in the study ELISA EV-TRACK -
4 Experiment ID 2133 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method ELISA PubMed ID 36515353    Organism Homo sapiens Experiment description Oral nicotinamide riboside raises NAD+ and lowers biomarkers of neurodegenerative pathology in plasma extracellular vesicles enriched for neuronal origin Authors Vreones M, Mustapic M, Moaddel R, Pucha KA, Lovett J, Seals DR, Kapogiannis D, Martens CR. Journal name Aging Cell Publication year 2023 Sample Plasma Sample name Patient-derived neuronal origin EVs (enriched) - responders Isolation/purification methods ExoQuick Kit Centrifugation Flotation density - Molecules identified in the study Metabolite Protein Methods used in the study ELISA EV-TRACK -