Gene description for ITGA4
Gene name	integrin subunit alpha 4
Gene symbol	ITGA4
Other names/aliases	CD49D IA4
Species	Homo sapiens
Experiment description of studies that identified ITGA4 in Endothelial cells
1 Experiment ID 309 Identified molecule protein Extracellular vesicle type Microvesicles MISEV EVs Identification method FACS PubMed ID 17536014    Organism Homo sapiens Experiment description Endothelial progenitor cell derived microvesicles activate an angiogenic program in endothelial cells by a horizontal transfer of Mrna Authors Deregibus MC, Cantaluppi V, Calogero R, Lo Iacono M, Tetta C, Biancone L, Bruno S, Bussolati B, Camussi G Journal name Blood Publication year 2007 Sample Endothelial cells Sample name Endothelial cells - Healthy donors Isolation/purification methods Differential centrifugation Ultracentrifugation FACS Flotation density - Molecules identified in the study Protein mRNA Methods used in the study FACS RT-PCR Microarray [Illumina] EV-TRACK -
2 Experiment ID 551 Identified molecule protein Extracellular vesicle type Exosomes/Extracellular vesicles MISEV EVs Identification method Mass spectrometry PubMed ID 24009886    Organism Homo sapiens Experiment description Cellular stress conditions are reflected in the protein and RNA content of endothelial cell-derived exosomes. Authors de Jong OG, Verhaar MC, Chen Y, Vader P, Gremmels H, Posthuma G, Schiffelers RM, Gucek M, van Balkom BW. Journal name J Extracell Vesicles Publication year 2012 Sample Endothelial cells Sample name Stressed (hypoxia, TNF-alpha-induced activation, high glucose and mannose concentrations)-Endothelial cells (HMEC-1) Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV120004: EV-METRIC:67%