Gene description for ITGB4
Gene name	integrin subunit beta 4
Gene symbol	ITGB4
Other names/aliases	CD104 GP150 JEB5A JEB5B
Species	Homo sapiens
Experiment description of studies that identified ITGB4 in Plasma
1 Experiment ID 3308 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method ELISA PubMed ID 32139701    Organism Homo sapiens Experiment description Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation Authors Ji Q, Zhou L, Sui H, Yang L, Wu X, Song Q, Jia R, Li R, Sun J, Wang Z, Liu N, Feng Y, Sun X, Cai G, Feng Y, Cai J, Cao Y, Cai G, Wang Y, Li Q. Journal name Nat Commun Publication year 2020 Sample Plasma Sample name Non-metastatic colorectal cancer patients Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting ELISA EV-TRACK -
2 Experiment ID 3310 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method ELISA PubMed ID 32139701    Organism Homo sapiens Experiment description Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation Authors Ji Q, Zhou L, Sui H, Yang L, Wu X, Song Q, Jia R, Li R, Sun J, Wang Z, Liu N, Feng Y, Sun X, Cai G, Feng Y, Cai J, Cao Y, Cai G, Wang Y, Li Q. Journal name Nat Commun Publication year 2020 Sample Plasma Sample name Colorectal cancer patients with lung metastasis Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study ELISA EV-TRACK -
3 Experiment ID 3311 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method ELISA PubMed ID 32139701    Organism Homo sapiens Experiment description Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation Authors Ji Q, Zhou L, Sui H, Yang L, Wu X, Song Q, Jia R, Li R, Sun J, Wang Z, Liu N, Feng Y, Sun X, Cai G, Feng Y, Cai J, Cao Y, Cai G, Wang Y, Li Q. Journal name Nat Commun Publication year 2020 Sample Plasma Sample name Colorectal cancer patients with liver metastasis Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study ELISA EV-TRACK -