Gene description for KRT10 |
Gene name |
keratin 10 |
Gene symbol |
KRT10 |
Other names/aliases |
BCIE BIE CK10 EHK EHK2 IHL K10 KPP |
Species |
Homo sapiens |
Experiment description of studies that identified KRT10 in Urine |
1
|
Experiment ID | 180 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
MISEV | EVs |
Identification method | Mass spectrometry [MALDI TOF]
|
PubMed ID |
20686450
|
Organism | Homo sapiens |
Experiment description | Comparison of three methods for isolation of urinary microvesicles to identify biomarkers of nephrotic syndrome |
Authors | Rood IM, Deegens JK, Merchant ML, Tamboer WP, Wilkey DW, Wetzels JF, Klein JB |
Journal name |
Kidney Int
|
Publication year | 2010 |
Sample | Urine |
Sample name | Urine - SEC |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Size exclusion chromatography Filtration |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting Mass spectrometry [MALDI TOF] |
EV-TRACK |
EV100026: EV-METRIC:33%, 25%, 44%
|
|
|
2
|
Experiment ID | 382 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
18373357
|
Organism | Homo sapiens |
Experiment description | Isolation and identification of potential urinary microparticle biomarkers of bladder cancer. |
Authors | Smalley DM, Sheman NE, Nelson K, Theodorescu D. |
Journal name |
J Proteome Res
|
Publication year | 2008 |
Sample | Urine |
Sample name | Normal donors-Urine |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
3
|
Experiment ID | 383 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
18373357
|
Organism | Homo sapiens |
Experiment description | Isolation and identification of potential urinary microparticle biomarkers of bladder cancer. |
Authors | Smalley DM, Sheman NE, Nelson K, Theodorescu D. |
Journal name |
J Proteome Res
|
Publication year | 2008 |
Sample | Urine |
Sample name | Patients of bladder cancer-Urine |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
4
|
Experiment ID | 429 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
21595033
|
Organism | Homo sapiens |
Experiment description | Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy. |
Authors | Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC. |
Journal name |
Proteomics
|
Publication year | 2011 |
Sample | Urine |
Sample name | Normal donors-Urine |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV110019: EV-METRIC:44%
|
|
|
5
|
Experiment ID | 430 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
21595033
|
Organism | Homo sapiens |
Experiment description | Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy. |
Authors | Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC. |
Journal name |
Proteomics
|
Publication year | 2011 |
Sample | Urine |
Sample name | Patients of basement membrane nephropathy-Urine |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV110019: EV-METRIC:44%
|
|
|
6
|
Experiment ID | 431 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
21595033
|
Organism | Homo sapiens |
Experiment description | Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy. |
Authors | Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC. |
Journal name |
Proteomics
|
Publication year | 2011 |
Sample | Urine |
Sample name | Patients of early IgA nephropathy-Urine |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV110019: EV-METRIC:44%
|
|
|
7
|
Experiment ID | 437 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Membrane vesicles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
22106071
|
Organism | Homo sapiens |
Experiment description | Proteomic analysis of urine exosomes by multidimensional protein identification technology (MudPIT). |
Authors | Wang Z, Hill S, Luther JM, Hachey DL, Schey KL. |
Journal name |
Proteomics
|
Publication year | 2012 |
Sample | Urine |
Sample name | Normal donors-Urine |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV120168: EV-METRIC:14%
|
|
|
8
|
Experiment ID | 498 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Membrane vesicles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
23376485
|
Organism | Homo sapiens |
Experiment description | Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. |
Authors | Prunotto M, Farina A, Lane L, Pernin A, Schifferli J, Hochstrasser DF, Lescuyer P, Moll S. |
Journal name |
J Proteomics
|
Publication year | 2013 |
Sample | Urine |
Sample name | Normal-Urine |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130051: EV-METRIC:38%
|
|
|
9
|
Experiment ID | 512 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Microvesicles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
23533145
|
Organism | Homo sapiens |
Experiment description | In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. |
Authors | Principe S, Jones EE, Kim Y, Sinha A, Nyalwidhe JO, Brooks J, Semmes OJ, Troyer DA, Lance RS, Kislinger T, Drake RR. |
Journal name |
Proteomics
|
Publication year | 2013 |
Sample | Urine |
Sample name | Low-grade prostate cancer patient-Expressed prostatic secretions in urine |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130224: EV-METRIC:14%
|
|
|
10
|
Experiment ID | 513 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Microvesicles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
23533145
|
Organism | Homo sapiens |
Experiment description | In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. |
Authors | Principe S, Jones EE, Kim Y, Sinha A, Nyalwidhe JO, Brooks J, Semmes OJ, Troyer DA, Lance RS, Kislinger T, Drake RR. |
Journal name |
Proteomics
|
Publication year | 2013 |
Sample | Urine |
Sample name | Normal-Expressed prostatic secretions in urine |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV130224: EV-METRIC:14%
|
|
|
11
|
Experiment ID | 725 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
25471207
|
Organism | Homo sapiens |
Experiment description | Intraluminal proteome and peptidome of human urinary extracellular vesicles. |
Authors | Liu X, Chinello C, Musante L, Cazzaniga M, Tataruch D, Calzaferri G, James Smith A, De Sio G, Magni F, Zou H, Holthofer H. |
Journal name |
Proteomics Clin Appl.
|
Publication year | 2015 |
Sample | Urine |
Sample name | Normal crude urine- Trypsinized |
Isolation/purification methods | Differential centrifugation Hydrostatic filtration dialysis Ultrafiltration |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV140189: EV-METRIC:25%
|
|
|
12
|
Experiment ID | 751 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
29988836
|
Organism | Homo sapiens |
Experiment description | Ultrafiltration and size exclusion chromatography combined with asymmetrical-flow field-flow fractionation for the isolation and characterisation of extracellular vesicles from urine |
Authors | Oeyen E, Van Mol K, Baggerman G, Willems H, Boonen K, Rolfo C, Pauwels P, Jacobs A, Schildermans K, Cho WC, Mertens I. |
Journal name |
J Extracell Vesicles
|
Publication year | 2018 |
Sample | Urine |
Sample name | Urine - Fraction 8 and 9 pooled |
Isolation/purification methods | Filtration Size exclusion chromatography |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV170025: EV-METRIC:62%
|
|
|
13
|
Experiment ID | 1027 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
24211404
|
Organism | Homo sapiens |
Experiment description | Diabetic nephropathy induces changes in the proteome of human urinary exosomes as revealed by label-free comparative analysis. |
Authors | Zubiri I, Posada-Ayala M, Sanz-Maroto A, Calvo E, Martin-Lorenzo M, Gonzalez-Calero L, de la Cuesta F, Lopez JA, Fernandez-Fernandez B, Ortiz A, Vivanco F, Alvarez-Llamas G. |
Journal name |
J Proteomics.
|
Publication year | 2014 |
Sample | Urine |
Sample name | Urine - Diabetic nephropathy (DN) patients |
Isolation/purification methods | Ultracentrifugation ExoQuick |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV140245: EV-METRIC:22%, 25%, 22%
|
|
|