Gene description for MMP2
Gene name matrix metallopeptidase 2
Gene symbol MMP2
Other names/aliases CLG4
CLG4A
MMP-2
MMP-II
MONA
TBE-1
Species Homo sapiens
 Experiment description of studies that identified MMP2 in Plasma

1
Experiment ID2850
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 35058437   
OrganismHomo sapiens
Experiment descriptionCirculating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2
AuthorsEl-Shennawy L, Hoffmann AD, Dashzeveg NK, McAndrews KM, Mehl PJ, Cornish D, Yu Z, Tokars VL, Nicolaescu V, Tomatsidou A, Mao C, Felicelli CJ, Tsai CF, Ostiguin C, Jia Y, Li L, Furlong K, Wysocki J, Luo X, Ruivo CF, Batlle D, Hope TJ, Shen Y, Chae YK, Zhang H, LeBleu VS, Shi T, Swaminathan S, Luo Y, Missiakas D, Randall GC, Demonbreun AR, Ison MG, Kalluri R, Fang D, Liu H.
Journal name Nat Commun
Publication year2022
SamplePlasma
Sample nameCSB-012 - COVID-19 patient - convalescent phase
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Mass spectrometry
EV-TRACK -

2
Experiment ID3087
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Immuno-EM
PubMed ID 36631249   
OrganismHomo sapiens
Experiment descriptionS100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos
AuthorsWang X, Huang H, Sze KM, Wang J, Tian L, Lu J, Tsui YM, Ma HT, Lee E, Chen A, Lee J, Wang Y, Yam JWP, Cheung TT, Guan X, Ng IO.
Journal name Gut
Publication year2023
SamplePlasma
Sample nameHepatocellular carcinoma patients
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Immuno-EM
EV-TRACK -

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