Gene description for CYTB
Gene name mitochondrially encoded cytochrome b
Gene symbol CYTB
Other names/aliases MTCYB
Species Homo sapiens
 Experiment description of studies that identified CYTB in Breast cancer cells

1
Experiment ID579
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Mass spectrometry [LTQ]
PubMed ID 27894104   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
AuthorsHurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr.
Journal name Oncotarget
Publication year2016
SampleBreast cancer cells
Sample nameMDA-MB-468
Isolation/purification methodsDifferential centrifugation
Polymer-based precipitation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
EV-TRACK -

2
Experiment ID1758
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 35918900   
OrganismHomo sapiens
Experiment descriptionCharacterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL)
AuthorsBauzá-Martinez J, Armony G, Pronker MF, Wu W.
Journal name J Extracell Vesicles
Publication year2022
SampleBreast cancer cells
Sample nameMDA-MB-231
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectometry
Western blotting
EV-TRACK -

3
Experiment ID1760
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 35918900   
OrganismHomo sapiens
Experiment descriptionCharacterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL)
AuthorsBauzá-Martinez J, Armony G, Pronker MF, Wu W.
Journal name J Extracell Vesicles
Publication year2022
SampleBreast cancer cells
Sample nameMDA-MB-231
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectometry
EV-TRACK -

4
Experiment ID3350
Identified moleculeprotein
Extracellular vesicle typeSupermeres
MISEVEV-like nanoparticles
Identification method Mass spectrometry
PubMed ID 34887515   
OrganismHomo sapiens
Experiment descriptionSupermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
AuthorsZhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ.
Journal name Nat Cell Biol
Publication year2021
SampleBreast cancer cells
Sample nameMDA-MB-231
Isolation/purification methodsDifferential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Mass spectrometry
ELISA
EV-TRACK -

<