Gene description for P4HB
Gene name prolyl 4-hydroxylase subunit beta
Gene symbol P4HB
Other names/aliases CLCRP1
DSI
ERBA2L
GIT
P4Hbeta
PDI
PDIA1
PHDB
PO4DB
PO4HB
PROHB
Species Homo sapiens
 Experiment description of studies that identified P4HB in Liver cancer cells

1
Experiment ID2476
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 34401050   
OrganismHomo sapiens
Experiment descriptionTPI1-reduced extracellular vesicles mediated by Rab20 downregulation promotes aerobic glycolysis to drive hepatocarcinogenesis
AuthorsLiu BHM, Tey SK, Mao X, Ma APY, Yeung CLS, Wong SWK, Ng TH, Xu Y, Yao Y, Fung EYM, Tan KV, Khong PL, Ho DW, Ng IO, Tang AHN, Cai SH, Yun JP, Yam JWP.
Journal name J Extracell Vesicles
Publication year2021
SampleLiver cancer cells
Sample nameMHCC97L
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Immuno-EM
Mass spectrometry
EV-TRACK -

2
Experiment ID2477
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 34401050   
OrganismHomo sapiens
Experiment descriptionTPI1-reduced extracellular vesicles mediated by Rab20 downregulation promotes aerobic glycolysis to drive hepatocarcinogenesis
AuthorsLiu BHM, Tey SK, Mao X, Ma APY, Yeung CLS, Wong SWK, Ng TH, Xu Y, Yao Y, Fung EYM, Tan KV, Khong PL, Ho DW, Ng IO, Tang AHN, Cai SH, Yun JP, Yam JWP.
Journal name J Extracell Vesicles
Publication year2021
SampleLiver cancer cells
Sample nameMHCC97L
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Immuno-EM
Mass spectrometry
EV-TRACK -

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