Gene description for PFN1
Gene name	profilin 1
Gene symbol	PFN1
Other names/aliases	ALS18
Species	Homo sapiens
Experiment description of studies that identified PFN1 in Neuroblastoma cells
1 Experiment ID 556 Identified molecule protein Extracellular vesicle type Exosomes/Membrane vesicles MISEV EVs Identification method Mass spectrometry PubMed ID 24069378    Organism Homo sapiens Experiment description Proteome profiling of neuroblastoma-derived exosomes reveal the expression of proteins potentially involved in tumor progression. Authors Marimpietri D, Petretto A, Raffaghello L, Pezzolo A, Gagliani C, Tacchetti C, Mauri P, Melioli G, Pistoia V. Journal name PLoS One Publication year 2013 Sample Neuroblastoma cells Sample name HTLA-230 Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130101: EV-METRIC:38%, 14%
2 Experiment ID 1153 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 22057275    Organism Homo sapiens Experiment description Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease. Authors Saman S, Kim W, Raya M, Visnick Y, Miro S, Saman S, Jackson B, McKee AC, Alvarez VE, Lee NC, Hall GF. Journal name J Biol Chem Publication year 2012 Sample Neuroblastoma cells Sample name M1C cells (inducibly expressing wild-type human tau Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV120107: EV-METRIC:11%, 11%