Gene description for ABCB4
Gene name ATP binding cassette subfamily B member 4
Gene symbol ABCB4
Other names/aliases ABC21
GBD1
ICP3
MDR2
MDR2/3
MDR3
PFIC-3
PGY3
Species Homo sapiens
 Experiment description of studies that identified ABCB4 in Serum

1
Experiment ID971
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Mass spectrometry
PubMed ID 22808001   
OrganismHomo sapiens
Experiment descriptionBiochemical and physical characterisation of urinary nanovesicles following CHAPS treatment.
AuthorsMusante L, Saraswat M, Duriez E, Byrne B, Ravidà, Domon B, Holthofer H.
Journal name PLoS One
Publication year2012
SampleSerum
Sample nameSerum -Tuberculosis patient 1
Isolation/purification methodsFiltration
ExoQuick
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV120006: EV-METRIC:56%

2
Experiment ID965
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Western blotting
PubMed ID 25844599   
OrganismHomo sapiens
Experiment descriptionMolecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
AuthorsKharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, UlléA, Yachnin J, Nilsson S, Panaretakis T.
Journal name Oncotarget
Publication year2015
SampleSerum
Sample namecastration resistant prostate cancer patient - R1
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Density gradient centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK EV150027: EV-METRIC:11%, 56%

3
Experiment ID967
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Western blotting
PubMed ID 25844599   
OrganismHomo sapiens
Experiment descriptionMolecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
AuthorsKharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, UlléA, Yachnin J, Nilsson S, Panaretakis T.
Journal name Oncotarget
Publication year2015
SampleSerum
Sample namecastration resistant prostate cancer patient - R3
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Density gradient centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK EV150027: EV-METRIC:11%, 56%

4
Experiment ID968
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Western blotting
PubMed ID 25844599   
OrganismHomo sapiens
Experiment descriptionMolecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
AuthorsKharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, UlléA, Yachnin J, Nilsson S, Panaretakis T.
Journal name Oncotarget
Publication year2015
SampleSerum
Sample namecastration resistant prostate cancer patient - S4
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Density gradient centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK EV150027: EV-METRIC:11%, 56%

5
Experiment ID969
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Western blotting
PubMed ID 25844599   
OrganismHomo sapiens
Experiment descriptionMolecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
AuthorsKharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, UlléA, Yachnin J, Nilsson S, Panaretakis T.
Journal name Oncotarget
Publication year2015
SampleSerum
Sample namecastration resistant prostate cancer patient - S5
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Density gradient centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK EV150027: EV-METRIC:11%, 56%

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