Gene description for HHIP
Gene name	hedgehog interacting protein
Gene symbol	HHIP
Other names/aliases	-
Species	Bos taurus
Experiment description of studies that identified HHIP in Bovine milk
1 Experiment ID 503 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 23459212    Organism Bos taurus Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis. Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD. Journal name J Proteomics Publication year 2013 Sample Bovine milk Sample name Staphylococcus aureus-infected-Milk Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130111: EV-METRIC:43%
2 Experiment ID 2815 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 34168137    Organism Bos taurus Experiment description Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Authors Samuel M, Fonseka P, Sanwlani R, Gangoda L, Chee SH, Keerthikumar S, Spurling A, Chitti SV, Zanker D, Ang CS, Atukorala I, Kang T, Shahi S, Marzan AL, Nedeva C, Vennin C, Lucas MC, Cheng L, Herrmann D, Pathan M, Chisanga D, Warren SC, Zhao K, Abraham N, Anand S, Boukouris S, Adda CG, Jiang L, Shekhar TM, Baschuk N, Hawkins CJ, Johnston AJ, Orian JM, Hoogenraad NJ, Poon IK, Hill AF, Jois M, Timpson P, Parker BS, Mathivanan S. Journal name Nat Commun Publication year 2021 Sample Bovine milk Sample name Raw milk Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein mRNA miRNA tRNA Methods used in the study Western blotting Mass spectrometry Small RNA sequencing EV-TRACK -
3 Experiment ID 2822 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 34168137    Organism Bos taurus Experiment description Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Authors Samuel M, Fonseka P, Sanwlani R, Gangoda L, Chee SH, Keerthikumar S, Spurling A, Chitti SV, Zanker D, Ang CS, Atukorala I, Kang T, Shahi S, Marzan AL, Nedeva C, Vennin C, Lucas MC, Cheng L, Herrmann D, Pathan M, Chisanga D, Warren SC, Zhao K, Abraham N, Anand S, Boukouris S, Adda CG, Jiang L, Shekhar TM, Baschuk N, Hawkins CJ, Johnston AJ, Orian JM, Hoogenraad NJ, Poon IK, Hill AF, Jois M, Timpson P, Parker BS, Mathivanan S. Journal name Nat Commun Publication year 2021 Sample Bovine milk Sample name Commercial milk Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein mRNA miRNA tRNA Methods used in the study Mass spectrometry Small RNA sequencing EV-TRACK -